Receptor
PDB id Resolution Class Description Source Keywords
2BVN 2.3 Å EC: 3.6.1.48 E. COLI EF-TU:GDPNP IN COMPLEX WITH THE ANTIBIOTIC ENACYLOXIN IIA ESCHERICHIA COLI TRANSLATION ELONGATION FACTOR GTPASE ANTIBIOTIC GTP- BINDING PHOSPHORYLATION
Ref.: ENACYLOXIN IIA PINPOINTS A BINDING POCKET OF ELONGATION FACTOR TU FOR DEVELOPMENT OF NOVEL ANTIBIOTICS. J.BIOL.CHEM. V. 281 2893 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ENX A:1396;
B:1396;
Valid;
Valid;
none;
none;
submit data
702.616 C33 H45 Cl2 N O11 CC/C=...
GNP A:1394;
B:1394;
Valid;
Valid;
none;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
MG A:1395;
B:1395;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2BVN 2.3 Å EC: 3.6.1.48 E. COLI EF-TU:GDPNP IN COMPLEX WITH THE ANTIBIOTIC ENACYLOXIN IIA ESCHERICHIA COLI TRANSLATION ELONGATION FACTOR GTPASE ANTIBIOTIC GTP- BINDING PHOSPHORYLATION
Ref.: ENACYLOXIN IIA PINPOINTS A BINDING POCKET OF ELONGATION FACTOR TU FOR DEVELOPMENT OF NOVEL ANTIBIOTICS. J.BIOL.CHEM. V. 281 2893 2006
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
3 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1D2E Kd = 1 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 4H9G - 14J C5 H3 Br O3 c1cc(oc1C(....
6 4LBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 4LC0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 1EXM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 2C78 - PUL C47 H66 O13 C[C@@H]1[C....
10 1EFT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4LBV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 4LBW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 1HA3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 4J0Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1D2E Kd = 1 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1DG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2BVN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 4H9G - 14J C5 H3 Br O3 c1cc(oc1C(....
6 4LBZ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
7 4LC0 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 1EXM - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
9 2C78 - PUL C47 H66 O13 C[C@@H]1[C....
10 1EFT - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
11 4LBV - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
12 4LBW - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
13 1HA3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 4J0Q - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 1SKQ - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 1JNY - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 3WYA - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ENX; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 ENX 1 1
Ligand no: 2; Ligand: GNP; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 GDP 0.839506 0.973684
3 GP3 0.82716 0.948718
4 GTP 0.809524 0.973684
5 GNH 0.807229 0.986842
6 G1R 0.77907 0.961039
7 GCP 0.77907 0.948718
8 GSP 0.770115 0.925
9 5GP 0.756098 0.960526
10 G 0.756098 0.960526
11 G2R 0.747253 0.936709
12 GMV 0.747126 0.948718
13 GAV 0.714286 0.936709
14 GP2 0.712644 0.936709
15 G2P 0.711111 0.936709
16 Y9Z 0.708333 0.880952
17 GDP MG 0.696629 0.9
18 GDD 0.690722 0.936709
19 GDC 0.690722 0.936709
20 GKE 0.690722 0.936709
21 GDP BEF 0.688889 0.878049
22 G5P 0.686869 0.948718
23 GPG 0.684211 0.936709
24 GTG 0.683673 0.91358
25 GFB 0.683673 0.936709
26 GDR 0.683673 0.936709
27 JB2 0.68 0.936709
28 GKD 0.68 0.936709
29 G3A 0.676768 0.948718
30 6CK 0.676768 0.91358
31 GDX 0.673267 0.948718
32 ALF 5GP 0.67033 0.86747
33 GTP MG 0.666667 0.9
34 BEF GDP 0.666667 0.86747
35 YGP 0.663265 0.879518
36 GCP G 0.659574 0.911392
37 GPD 0.656863 0.902439
38 GDP AF3 0.645833 0.86747
39 GDP ALF 0.645833 0.86747
40 JB3 0.641509 0.925
41 DBG 0.640351 0.974359
42 G3D 0.638298 0.960526
43 G4P 0.625 0.960526
44 GMP 0.621951 0.857143
45 NGD 0.62037 0.936709
46 GGM 0.618182 0.925926
47 0O2 0.616162 0.960526
48 G G 0.61 0.911392
49 2MD 0.603604 0.870588
50 CAG 0.60177 0.904762
51 U2G 0.590909 0.91358
52 FEG 0.590909 0.858824
53 GDP 7MG 0.590476 0.888889
54 MGD 0.587719 0.870588
55 ZGP 0.585586 0.848837
56 CG2 0.580357 0.91358
57 ANP 0.568421 0.922078
58 PGD 0.567797 0.902439
59 MD1 0.567797 0.870588
60 3GP 0.56044 0.922078
61 TPG 0.558333 0.822222
62 GH3 0.55 0.948052
63 FE9 0.546219 0.778947
64 GPX 0.539216 0.922078
65 G4M 0.539062 0.860465
66 DGI 0.536082 0.9
67 BGO 0.535088 0.901235
68 IDP 0.53125 0.947368
69 DGT 0.53 0.9
70 2GP 0.526882 0.935065
71 G1R G1R 0.520325 0.901235
72 I2C FE2 CMO CMO 0.516667 0.811111
73 U A G G 0.512605 0.911392
74 AGO 0.504202 0.91358
75 G A A A 0.504202 0.9
76 P2G 0.5 0.860759
77 G1G 0.5 0.902439
78 MGP 0.49505 0.936709
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 DGP 0.474227 0.8875
83 DG 0.474227 0.8875
84 G G U 0.473684 0.911392
85 IMP 0.463918 0.934211
86 G2Q 0.462963 0.936709
87 GPC 0.459677 0.858824
88 G C 0.459016 0.878049
89 GTA 0.448276 0.91358
90 G7M 0.444444 0.924051
91 MAP 0.439252 0.898734
92 G G G RPC 0.435484 0.853659
93 B4P 0.434343 0.871795
94 AP5 0.434343 0.871795
95 ADP 0.434343 0.896104
96 A2D 0.43299 0.871795
97 U G A 0.431655 0.86747
98 G G G C 0.426357 0.890244
99 SGP 0.425743 0.807229
100 AU1 0.425743 0.922078
101 BA3 0.424242 0.871795
102 35G 0.423077 0.909091
103 PCG 0.423077 0.909091
104 A G C C 0.423077 0.888889
105 C2E 0.423077 0.897436
106 APC G U 0.421875 0.864198
107 ATP 0.421569 0.896104
108 ACQ 0.419048 0.873418
109 5GP 5GP 0.419048 0.860759
110 AQP 0.417476 0.896104
111 5FA 0.417476 0.896104
112 01G 0.417391 0.880952
113 UNP 0.415842 0.810127
114 AN2 0.415842 0.909091
115 6AD 0.415094 0.821429
116 ITT 0.411765 0.846154
117 M33 0.411765 0.860759
118 G C C C 0.410448 0.901235
119 G U34 0.408 0.86747
120 ACP 0.407767 0.873418
121 APR 0.403846 0.871795
122 AR6 0.403846 0.871795
123 DG DG 0.403509 0.845238
124 A4P 0.403226 0.848837
125 UCG 0.402985 0.888889
126 AD9 0.4 0.873418
127 SAP 0.4 0.851852
128 AGS 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2BVN; Ligand: ENX; Similar sites found: 6
This union binding pocket(no: 1) in the query (biounit: 2bvn.bio2) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1J78 OLA 0.005762 0.45164 2.29008
2 3TDC 0EU 0.005079 0.47778 2.54453
3 4UCC ZKW 0.03649 0.40447 2.57511
4 5LFV SIA GAL NAG 0.02206 0.40562 3.15457
5 1OFL NGK GCD 0.0219 0.40798 5.08906
6 5OCA 9QZ 0.00179 0.49367 8.29493
Pocket No.: 2; Query (leader) PDB : 2BVN; Ligand: GNP; Similar sites found: 561
This union binding pocket(no: 2) in the query (biounit: 2bvn.bio2) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1EK0 GNP 0.00000000003897 0.79621 None
2 1D5C GDP 0.000000001553 0.70189 1.23457
3 1YTM ATP 0.0001288 0.45221 1.27226
4 2WKQ GTP 0.000000004069 0.60119 1.50602
5 1V8K ANP 0.00001135 0.49803 1.52672
6 5TSH ANP 0.00008358 0.46247 1.52672
7 5XDR ADP 0.002816 0.42947 1.52672
8 5TSH ADP 0.0003779 0.4174 1.52672
9 4FCW ADP 0.0003258 0.44961 1.60772
10 1Z0F GDP 0.00000000009012 0.71743 1.67598
11 2GWH A3P 0.004558 0.41359 1.67785
12 3ZS9 ADP ALF 0.000004273 0.56618 1.69492
13 2WOJ ADP ALF 0.000006798 0.45842 1.69492
14 2G77 GDP 0.0000000004849 0.6986 1.78117
15 2G77 AF3 0.0000653 0.53211 1.78117
16 5LB3 ADP 0.0002656 0.48939 1.78117
17 5HR5 ADP 0.0005946 0.45306 1.78117
18 2XAU ADP 0.002621 0.41624 1.78117
19 1P9B GDP 0.00002393 0.51525 1.80995
20 4ZNL BEF ADP 0.0000515 0.51018 1.82482
21 1TAD GDP 0.0000000002376 0.76911 1.85185
22 1TAD ALF 0.0000000002376 0.58492 1.85185
23 1U0J ADP 0.002409 0.40126 1.87266
24 5L3W GDP 0.00001531 0.51317 1.96078
25 2F9L GDP 0.00000000238 0.70773 2.01005
26 3IO3 ADP 0.00004816 0.50428 2.01149
27 1JWY GDP 0.0000002601 0.59941 2.03562
28 5KSZ GCP 0.0000004082 0.59899 2.03562
29 5IRN ADP 0.0001063 0.4838 2.03562
30 1JWY ADP 0.0001227 0.46276 2.03562
31 5VGR GDP 0.0003712 0.45071 2.03562
32 1XKV ATP 0.0006355 0.44424 2.03562
33 1OIX GDP 0.000000000536 0.74375 2.09424
34 1OIV GDP 0.000000001346 0.72533 2.09424
35 1G6O ADP 0.0002897 0.46978 2.12121
36 1MH1 GNP 0.0000000003191 0.59959 2.15054
37 1G4U GDP 0.0000001108 0.62259 2.17391
38 5MEX SZZ 0.02333 0.40461 2.17391
39 5MEX PAP 0.009911 0.40042 2.17391
40 2B8T THM 0.01086 0.40218 2.24215
41 4LX0 BEF GDP 0.00000000003671 0.80072 2.25989
42 3DEF GDP 0.00001189 0.52591 2.29008
43 2DPY ADP 0.0004912 0.48276 2.29008
44 2VVG ADP 0.0000006582 0.47322 2.29008
45 1K6M AGS 0.001112 0.44909 2.29008
46 4A4Z ANP 0.001142 0.4213 2.29008
47 1VHT BA3 0.0002781 0.45885 2.29358
48 5HCN GCP 0.000000002858 0.70775 2.29885
49 4LHW GNP 0.0000000005259 0.60528 2.29885
50 4R2I ANP 0.003751 0.43842 2.38095
51 2D7C GTP 0.000000000371 0.75112 2.39521
52 1E2K TMC 0.001599 0.46314 2.41692
53 3DZD ADP 0.001032 0.44007 2.44565
54 1R0X ATP 0.00008172 0.45127 2.44755
55 2ZFI ADP 0.00001118 0.54853 2.45902
56 3ZQ6 ADP ALF 0.00000283 0.57447 2.46914
57 4LPS GDP 0.0000000324 0.61273 2.47934
58 4P4T GDP 0.0000004936 0.55995 2.5
59 3FVQ ATP 0.0006694 0.45514 2.50696
60 1IHU AF3 0.00002632 0.52096 2.54453
61 1IHU ADP 0.00002956 0.52096 2.54453
62 4IOK ADP 0.0004288 0.47523 2.54453
63 4IOK XPO 0.000328 0.47523 2.54453
64 4HSE ADP 0.000153 0.45906 2.54453
65 1OYY AGS 0.001852 0.41338 2.54453
66 5K5Z ANP 0.0001385 0.43085 2.54777
67 5KSP GDP 0.00000009859 0.63636 2.63158
68 3R7F CP 0.01466 0.41148 2.63158
69 5BQ5 ADP BEF 0.0004403 0.46154 2.6455
70 1CR1 TTP 0.0002088 0.47797 2.7027
71 1F2U ATP 0.002554 0.43761 2.7027
72 3TMK T5A 0.0007452 0.46567 2.77778
73 2Y8E GNP 0.0000000000597 0.63597 2.7933
74 2QTV GNP 0.0000000005581 0.73977 2.79898
75 2C9O ADP 0.0003532 0.46768 2.79898
76 1G41 ADP 0.0002944 0.4571 2.79898
77 1F5N GNP 0.0000178 0.44647 2.79898
78 2VF7 ADP 0.000753 0.43219 2.79898
79 5J1J ANP 0.000008507 0.47713 2.80702
80 4TMK T5A 0.009 0.42015 2.8169
81 4BQS ADP 0.00007926 0.50805 2.84091
82 4PPF FLC 0.000008738 0.57437 2.85714
83 2ZR9 DTP 0.0001939 0.4493 2.86533
84 4WEI GLC GAL 0.004518 0.4406 2.88809
85 3QXC ATP 0.00007721 0.50799 2.89256
86 1SVM ATP 0.0011 0.4784 2.91777
87 2FFQ GSP 0.00000000001762 0.81547 2.92398
88 1R2Q GNP 0.00000000001732 0.83649 2.94118
89 1YZQ GNP 0.00000000001864 0.81434 2.94118
90 3QKT ANP 0.001757 0.44179 2.94985
91 3MJH GTP 0.000000000005018 0.83723 2.97619
92 1ZUI SKM 0.0001544 0.50694 2.97619
93 1RRC ADP 0.00002396 0.43831 2.99003
94 3Q72 GNP 0.00000000006823 0.68677 3.01205
95 1OE0 TTP 0.005781 0.42116 3.04348
96 1GOT GDP 0.00000002104 0.66149 3.05344
97 5I0H ADP BEF 0.000005342 0.5498 3.05344
98 5MZN ADP 0.001297 0.46159 3.05344
99 3EZ2 ADP 0.0002679 0.43377 3.05344
100 4IHQ ADP 0.000343 0.43113 3.05344
101 4YS0 ADP 0.00271 0.41444 3.05344
102 1GOJ ADP 0.0000005247 0.65281 3.09859
103 2XTZ GSP 0.00000000006361 0.78641 3.10734
104 3ZFD ANP 0.00001196 0.51668 3.1339
105 3CPJ GDP 0.000000006326 0.67087 3.13901
106 3VX3 ADP 0.0006288 0.45422 3.22581
107 4DKX GDP 0.00000000004752 0.80421 3.24074
108 2FH5 GTP 0.00000000005764 0.77391 3.24324
109 1P72 ADP 0.00164 0.45396 3.29341
110 4KFU ACP 0.000006651 0.47519 3.30189
111 1QF5 GDP 0.00001868 0.56812 3.30789
112 4LYA ATP 0.00004492 0.51293 3.30789
113 4PFO ADP 0.0001432 0.49369 3.30789
114 1QF5 RPL 0.003313 0.48562 3.30789
115 4XGU ADP 0.00006339 0.48327 3.30789
116 4PJ3 ANP 0.002506 0.423 3.30789
117 4O48 ASP 0.01473 0.41146 3.31325
118 2B8W ALF 5GP 0.00002046 0.53049 3.35366
119 2OZE AGS 0.0006255 0.45433 3.3557
120 2FNA ADP 0.0000846 0.44859 3.36134
121 1JJV ATP 0.00001162 0.46717 3.39806
122 3FYH ADP 0.001147 0.45028 3.41615
123 4PX9 ADP 0.0005361 0.47449 3.42466
124 5X40 ACP 0.001593 0.44196 3.42466
125 1T5C ADP 0.000001071 0.46568 3.4384
126 3B7G ANP 0.001372 0.42261 3.47826
127 3UIE ANP 0.0001011 0.47672 3.5
128 4GOX A3P 0.0006464 0.45984 3.51438
129 2ZE7 AMP 0.01098 0.40674 3.55731
130 2ZE7 DST 0.01181 0.40674 3.55731
131 1W0J ADP 0.00003257 0.50653 3.56234
132 1W0J ADP BEF 0.0004939 0.45893 3.56234
133 2ZPA ADP 0.001283 0.44033 3.56234
134 2CK3 ANP 0.0005056 0.43533 3.56234
135 2CK3 ADP 0.0005471 0.4113 3.56234
136 3TBK ANP 0.001207 0.40598 3.56234
137 5G41 AP5 0.001556 0.46902 3.58744
138 5H56 TYD 0.0006536 0.46989 3.58974
139 5H56 ADP 0.0006536 0.46989 3.58974
140 1KAO GDP 0.000000006447 0.67434 3.59281
141 3H86 AP5 0.0005749 0.4783 3.64583
142 3LRE ADP 0.000002188 0.4591 3.66197
143 4XTR ADP 0.0000408 0.48046 3.68664
144 4XTR ATP 0.00001974 0.46572 3.68664
145 4XVU ATP 0.00002241 0.464 3.68664
146 1S3G AP5 0.001693 0.46194 3.68664
147 2Z5F A3P 0.0035 0.42271 3.69128
148 5UQW GDP 0.0000000002718 0.75409 3.7037
149 4GBM A3P 0.002756 0.43109 3.71517
150 4JLV ADP 0.0001055 0.44945 3.71747
151 2ZPT A3P 0.03004 0.41165 3.72881
152 3WYF GTP 0.0000000003835 0.75652 3.78151
153 4D0N GDP 0.000000005205 0.63181 3.78378
154 4WZ6 ATP 0.00001884 0.56117 3.7931
155 1TU3 GNP 0.000000000003131 0.84667 3.79747
156 1KMQ GNP 0.0000000008564 0.72798 3.80435
157 1Z06 GNP 0.00000000000792 0.82451 3.81679
158 2BCG GDP 0.000000003184 0.69173 3.81679
159 3FKQ ATP 0.0000511 0.48724 3.81679
160 2BIF SIN 0.001366 0.46974 3.81679
161 2BIF ANP 0.0008146 0.46974 3.81679
162 5IFS ADP 0.0003015 0.45633 3.81679
163 1R6B ADP 0.0002105 0.45562 3.81679
164 1JJ7 ADP 0.000005463 0.44386 3.84615
165 5GVR LMR 0.004031 0.43537 3.84615
166 1FNN ADP 0.001192 0.42159 3.85604
167 1MR3 G3D 0.000000000221 0.70349 3.8674
168 5M04 GDP 0.00000000001187 0.71715 3.88889
169 4XOI GTP 0.000000002005 0.7143 3.88889
170 1G8S MET 0.01579 0.40847 3.91304
171 1TX4 ALF GDP 0.0000000008031 0.62703 3.9548
172 3ZIA ADP 0.00006982 0.49187 3.95683
173 3ZIA ATP 0.00002855 0.49106 3.95683
174 2EW1 GNP 0.00000000001875 0.80369 3.9801
175 2ZTS ADP 0.0006883 0.42945 3.98406
176 4D0G GTP 0.0000000002291 0.75057 4
177 2QG6 NMN 0.0004059 0.47634 4.0201
178 3SBD GNP 0.0000000004959 0.60645 4.07125
179 2FAH GDP 0.0001013 0.48472 4.07125
180 3DC4 ADP 0.0000118 0.47795 4.07125
181 2AWN ADP 0.000004719 0.43219 4.07125
182 2FSH ANP 0.002409 0.40287 4.07125
183 4AG5 ADP 0.00005622 0.53527 4.08163
184 2Q2Y ADP 0.0002858 0.49936 4.08719
185 2Q2Y MKR 0.0003297 0.49512 4.08719
186 3QF7 ANP 0.001174 0.44206 4.10959
187 1ION ADP 0.00007184 0.4831 4.11523
188 3BOS CDP 0.00003706 0.47451 4.13223
189 3Q85 GNP 0.000000000009736 0.73662 4.14201
190 3TNF GNP 0.00000000002573 0.81109 4.16667
191 2GDJ ANP 0.0001526 0.45086 4.16667
192 5E5U MLI 0.006632 0.41 4.16667
193 1L3I SAH 0.01606 0.40052 4.16667
194 4HDO GNP 0.00000000007847 0.78545 4.19162
195 3X1Z GNP 0.00000000006136 0.60941 4.19162
196 4YC7 GNP 0.000000002267 0.7054 4.19948
197 2J59 GTP 0.00000000002475 0.79819 4.21687
198 1O3Y GTP 0.00000000004412 0.78674 4.21687
199 1J2J GTP 0.00000000008458 0.66214 4.21687
200 1G3Q ADP 0.0000218 0.4959 4.21941
201 4GOJ GNP 0.0000000000007213 0.86408 4.2328
202 2X77 GDP 0.000000001695 0.66913 4.2328
203 2J0V GDP 0.00000001678 0.62479 4.24528
204 3QBT GNP 0.00000000001705 0.65317 4.28571
205 5WRJ A3P 0.0049 0.42134 4.29043
206 5IRC GDP 0.0000002802 0.58651 4.30108
207 3RWO GDP 0.000000002393 0.71381 4.32432
208 4ZG4 VO4 ADP 0.00001466 0.46996 4.3257
209 3AQ4 GDP 0.00000000006441 0.72462 4.34783
210 5L3V GDP 0.000002667 0.56205 4.34783
211 5L3S GNP 0.0000006196 0.51048 4.36242
212 5L3S G 0.01943 0.40623 4.36242
213 2HF9 GSP 0.00000006948 0.60994 4.42478
214 2CHG ANP 0.0004196 0.45981 4.42478
215 1RYH GNP 0.0000000003915 0.7098 4.4335
216 1HE1 GDP 0.0000001205 0.57033 4.44444
217 1HE1 AF3 0.0004977 0.48247 4.44444
218 2GCO GNP 0.0000000002871 0.73457 4.47761
219 2GCN GDP 0.000000008156 0.68017 4.47761
220 4U00 ADP 0.00002228 0.42828 4.5082
221 3NHB ADP 0.00006419 0.43753 4.57516
222 4ZI2 GNP 0.0000000000004464 0.75856 4.58015
223 1XMV ADP 0.0001146 0.46465 4.58015
224 1OS1 PYR 0.0009972 0.46128 4.58015
225 1OS1 ATP 0.0009922 0.45986 4.58015
226 5LTJ ADP 0.0003796 0.44395 4.58015
227 4NON GDP 0.000000006188 0.70035 4.61538
228 3Q9L ATP 0.00001549 0.52367 4.61538
229 4FRZ ADP 0.00001314 0.46218 4.66321
230 4V03 ADP 0.00005052 0.4892 4.66926
231 1Q20 PLO 0.009748 0.41849 4.68227
232 1Z08 GNP 0.0000000007324 0.73108 4.70588
233 1J99 AND 0.01638 0.40773 4.77816
234 2PZE ATP 0.000008929 0.44997 4.80349
235 1VG8 GNP 0.00000000002316 0.80999 4.83092
236 1VG0 GDP 0.000000002066 0.69238 4.83092
237 3N5C GDP 0.00000000002204 0.82009 4.83461
238 2A5F GTP 0.00000000003165 0.79692 4.83461
239 1NY5 ADP 0.001186 0.43968 4.83461
240 4XFR CIT 0.01323 0.41232 4.83461
241 3COB ADP 0.000002261 0.47308 4.87805
242 2JAQ DCP 0.008479 0.40876 4.87805
243 1DAK DPU 0.0000527 0.53753 4.91071
244 2IYL GDP 0.000004468 0.51899 4.92958
245 1KY3 GDP 0.000000004163 0.67891 4.94506
246 2W58 ADP 0.000006737 0.44118 4.9505
247 1RE0 GDP 0.000000000008875 0.71871 4.97738
248 5H67 ATP 0.01121 0.40153 5
249 4LJ9 ACP 0.0005486 0.43261 5.01475
250 2FJU GSP 0.0000000002978 0.74173 5.05618
251 4M9Q GNP 0.000000000002632 0.83858 5.08906
252 2ZEJ GDP 0.00000001218 0.68401 5.08906
253 1W5T ANP 0.0007549 0.45279 5.08906
254 1W5T ADP 0.002404 0.426 5.08906
255 3FB4 AP5 0.001264 0.46808 5.09259
256 4TTQ ATP 0.00006073 0.47255 5.11628
257 3KJI ADP 0.0001124 0.48271 5.11811
258 1KO8 6PG 0.001126 0.44286 5.14286
259 1H65 GDP 0.00002625 0.52101 5.18518
260 4YDS ATP 0.00003518 0.54021 5.26316
261 4DSU GDP 0.000000000355 0.7551 5.29101
262 5KUT GDP 0.00000002367 0.6186 5.29101
263 5JCZ GDP 0.00000001471 0.61926 5.34351
264 2NCD ADP 0.000009997 0.57419 5.34351
265 4R43 GDP 0.00008225 0.50728 5.34351
266 5FTB ANP 0.0001802 0.47912 5.34351
267 4IDN GNP 0.00007795 0.45139 5.34351
268 4D81 ADP 0.0006249 0.44973 5.34351
269 5FHD ADP ALF 0.0003833 0.43134 5.34351
270 4AF0 IMP 0.01262 0.40084 5.34351
271 1IN4 ADP 0.0005426 0.4571 5.38922
272 1VG1 GDP 0.000000000103 0.71516 5.40541
273 1VG9 GDP 0.0000000005124 0.68878 5.40541
274 1UKZ ADP 0.002048 0.45073 5.41872
275 1XP8 AGS 0.0001819 0.44165 5.46448
276 4XSH GSP 0.0000000005542 0.67994 5.47945
277 2CBZ ATP 0.0000008548 0.64806 5.48523
278 4MKG AP5 0.0007917 0.47794 5.52995
279 1L2T ATP 0.0007839 0.45788 5.53191
280 3T1O GDP 0.0000000008683 0.69544 5.55556
281 5MVR ADP 0.000009432 0.5005 5.55556
282 1UJ2 C5P 0.0001669 0.49249 5.55556
283 1UJ2 ADP 0.0002235 0.48662 5.55556
284 1WF3 GNP 0.00000000005392 0.79299 5.59796
285 1SVK ALF GDP 0.0000000007748 0.74785 5.59796
286 5KDO GDP 0.00000001906 0.60296 5.59796
287 1GP2 GDP 0.00000002282 0.57369 5.59796
288 3BFX A3P 0.001551 0.43663 5.59796
289 3PCR GTP 0.0000000001174 0.65823 5.60224
290 3E5H GNP 0.0000000003099 0.75472 5.61798
291 1XTQ GDP 0.00000000009014 0.77258 5.64972
292 3REF GDP 0.000000001998 0.70789 5.6701
293 1YRB GDP 0.0000000005762 0.71694 5.72519
294 3LXR GDP 0.00000002447 0.65439 5.72917
295 2RGX AP5 0.002223 0.45836 5.82524
296 2BEK ATP 0.0007998 0.47532 5.83658
297 5IRR GSP 0.0000006658 0.532 5.84416
298 5XCO GDP 0.000000002838 0.68628 5.84795
299 2IXE ATP 0.0006722 0.45711 5.85242
300 5M7P ADP 0.0006101 0.45481 5.85242
301 1G3M PCQ 0.008589 0.4267 5.85242
302 1IWE IMP 0.00004802 0.58023 5.9081
303 2BME GNP 0.00000000001543 0.81475 5.91398
304 1YZN GNP 0.0000000000334 0.80262 5.94595
305 1Y63 ADP 0.00001394 0.49448 5.97826
306 2QQ0 THM 0.0007359 0.46747 5.97826
307 2QQ0 ANP 0.0008496 0.46747 5.97826
308 2QQ0 TMP 0.0009249 0.46573 5.97826
309 4MKF AP5 0.001179 0.47069 5.99078
310 1BH2 GSP 0.000000002189 0.72406 6.03175
311 3FWY ADP 0.000007263 0.53833 6.05096
312 1TQ4 GDP 0.00000003136 0.59238 6.05327
313 2C5A NAD 0.0411 0.40539 6.0686
314 5GOE GDP 0.0000000004023 0.73524 6.10687
315 4WZA ACP 0.00000247 0.62202 6.10687
316 4WZA ADP 0.00000247 0.62202 6.10687
317 5I34 GDP 0.000007117 0.51758 6.10687
318 3T34 GDP 0.000004798 0.48999 6.10687
319 3DKP ADP 0.0005441 0.43133 6.12245
320 4U5X GNP 0.0000000002365 0.74238 6.17978
321 1M2O GNP 0.0000000002418 0.75968 6.31579
322 2PL3 ADP 0.0003862 0.42981 6.35593
323 4YLG GDP 0.0000000005052 0.69824 6.35838
324 1FP6 ADP 0.00004044 0.50237 6.36132
325 1X6V ADP 0.000192 0.49318 6.36132
326 1Z6T ADP 0.0005838 0.44129 6.36132
327 4IEE AGS 0.00273 0.43993 6.36132
328 4K81 GTP 0.0000000002061 0.76907 6.43275
329 4QM7 GTP 0.0001872 0.4481 6.43275
330 4V0K GDP 0.000000002211 0.71235 6.50888
331 5E95 GDP 0.000000006353 0.65207 6.54762
332 1GXU 2HP 0.00297 0.43827 6.59341
333 1NVV GNP 0.00000000003735 0.80037 6.62651
334 3DDC GNP 0.00000000005317 0.79327 6.62651
335 1NVU GTP 0.00000000008625 0.78354 6.62651
336 3KUD GDP 0.000000005273 0.68541 6.62651
337 1WQ1 GDP 0.00000001239 0.67504 6.62651
338 1CLU DBG 0.0000000002514 0.48343 6.62651
339 1WQ1 AF3 0.0001099 0.42379 6.62651
340 1JI0 ATP 0.00007441 0.52389 6.66667
341 3H4S ADP 0.000002804 0.46829 6.66667
342 4WOP CTP 0.0001608 0.44882 6.66667
343 2VB6 ADP BEF 0.0006295 0.46036 6.71141
344 2C5L GTP 0.00000000001616 0.81721 6.83761
345 2Y65 ADP 0.000001158 0.48142 6.84932
346 3CX8 GSP 0.0000000001796 0.77478 6.87023
347 3AB3 GDP 0.000000002632 0.69903 6.87023
348 1ZCB GDP 0.000000009965 0.68526 6.87023
349 1RJ9 GCP 0.000003249 0.59789 6.87023
350 2C04 GCP 0.00001903 0.50683 6.87023
351 1F9V ADP 0.00001637 0.45996 6.87023
352 1S9D GDP 0.0000000001172 0.77215 6.89655
353 5O2T GSP 0.00000000002182 0.6355 6.95187
354 4OI4 ATP 0.0001354 0.49081 6.95652
355 2GJ8 ALF GDP 0.000000000005034 0.6532 6.97674
356 2XT3 ADP 0.000003443 0.46789 6.97674
357 3MD0 GDP 0.00000000002587 0.69927 7.04225
358 1OXV ANP 0.00007644 0.45299 7.08215
359 2RCN GDP 0.0000000002236 0.68534 7.12468
360 4QOS ADP 0.0006546 0.45373 7.12468
361 3P4X ADP 0.0001809 0.44286 7.12468
362 1FZQ GDP 0.000000000005952 0.74801 7.18232
363 2EFE GNH 0.000000007789 0.66687 7.18232
364 4OHY ANP 0.00004674 0.44718 7.37913
365 5SZH GNP 0.00000000001145 0.82414 7.38916
366 4LC1 GDP 0.0000000005387 0.75402 7.4184
367 3RLF ANP 0.0007034 0.45816 7.43243
368 1ZJ6 G3D 0.00000000001927 0.74561 7.48663
369 2D7D ADP 0.002466 0.4079 7.5
370 2W2X GSP 0.0000000003447 0.73886 7.56757
371 2V7Q ATP 0.00002131 0.50583 7.57576
372 2V7Q ADP 0.0001318 0.45318 7.57576
373 1HTW ADP 0.00002465 0.49432 7.59494
374 3E70 GDP 0.000004867 0.52575 7.62195
375 1YVD GNP 0.00000000001843 0.8112 7.69231
376 1OW3 GDP 0.00000006676 0.6291 7.77202
377 2HV8 GTP 0.0000000005463 0.74337 7.8125
378 3TK1 GDP 0.0000000000399 0.67367 7.87879
379 2IS6 ADP 0.0002798 0.44054 7.88804
380 3B9Q MLI 0.00002918 0.55172 7.94702
381 1BG2 ADP 0.0000002421 0.48399 8
382 1B0U ATP 0.001659 0.43095 8.01527
383 1AQU A3P 0.003756 0.41735 8.08081
384 1YQT ADP 0.0001159 0.42988 8.14249
385 3TKL GTP 0.000000000008537 0.82301 8.16327
386 1FQK GDP 0.00000001937 0.6662 8.16327
387 1FQK ALF 0.00008928 0.42119 8.16327
388 5L3R GCP 0.0000001391 0.53348 8.19113
389 1GWN GTP 0.000000002863 0.69738 8.29268
390 1DS6 GDP 0.000000006703 0.62797 8.33333
391 1I4D GDP 0.000000007239 0.61363 8.33333
392 1E96 GTP 0.00000000139 0.72468 8.37438
393 3M1I GTP 0.0000000001663 0.77034 8.37696
394 2KIN ADP 0.0000004944 0.47546 8.40336
395 4C4P GNP 0.0000000001141 0.77792 8.41121
396 1PUJ GNP 0.00000000003564 0.77044 8.51064
397 4HI0 GDP 0.0000001556 0.56804 8.54271
398 3NKV GNP 0.00000000006842 0.78495 8.57143
399 2OFW ADX 0.0001762 0.50826 8.65385
400 1Z0K GTP 0.00000000001773 0.8048 8.72093
401 1T8U UAP SGN IDS SGN 0.002995 0.44994 8.82353
402 1T8U A3P 0.008283 0.40578 8.82353
403 3SFV GDP 0.000000007233 0.67922 8.83978
404 3A4M ADP 0.000007868 0.47923 8.84615
405 1S8F GDP 0.0000000002685 0.76372 8.90585
406 4DCT GDP 0.00000000006446 0.72441 8.90585
407 1YZG GDP 0.00000000002153 0.74405 8.93855
408 3NC9 TR3 0.02547 0.40469 8.94569
409 2XTN GTP 0.000008104 0.5466 8.97436
410 3B5J 12D 0.0001098 0.4408 9.0535
411 1R4A GNP 0.00000000002385 0.80255 9.09091
412 1LVG ADP 0.000001872 0.50395 9.09091
413 4GDX GLU 0.004683 0.44189 9.23077
414 4P32 ADP 0.001377 0.44296 9.23695
415 1M7B GTP 0.000000001554 0.6454 9.23913
416 4NE2 ADP 0.0003495 0.4886 9.28144
417 4NE2 SH2 0.0003982 0.4886 9.28144
418 2QEN ADP 0.00004851 0.50157 9.42857
419 3IIJ ADP 0.0000311 0.48073 9.44444
420 2PEZ DAT 0.0001147 0.50859 9.49721
421 3BFV ADP 0.000009824 0.55121 9.5941
422 1B7T ADP 0.0004426 0.44863 9.61539
423 1KK8 BEF ADP 0.0005613 0.45417 9.74026
424 4BFW ZVW 0.001126 0.47052 9.74843
425 1OFH ADP 0.0001943 0.46445 9.77011
426 5JCP GDP ALF 0.000000000268 0.71114 9.7852
427 4DID GDP 0.00000004522 0.60893 9.84456
428 5EE5 GTP 0.00000000001214 0.80845 9.85915
429 3KTA AP5 0.0007035 0.44745 9.89011
430 2WMO GTP 0.0000000001428 0.7285 10
431 1NJF AGS 0.00008667 0.49748 10
432 1NJF ADP 0.000235 0.4734 10
433 4BAS GNP 0.000000000182 0.7551 10.0503
434 1SQ5 ADP 0.00003763 0.48505 10.0649
435 5CK5 GDP 0.00000000342 0.6287 10.1266
436 4E03 ADP 0.00006377 0.47859 10.1942
437 1NF3 GNP 0.000000001394 0.59257 10.2564
438 1D2N ANP 0.0009546 0.44819 10.2941
439 1QF9 C5P 0.001131 0.46686 10.3093
440 5HPY GDP 0.00000007784 0.62612 10.3448
441 3GJ8 GDP 0.0000000001061 0.77416 10.4072
442 3GJ0 GDP 0.0000000002401 0.77072 10.4072
443 3GJ5 GDP 0.0000000001371 0.71274 10.4072
444 3GJ3 GDP 0.0000000001577 0.69265 10.4072
445 3GJ4 GDP 0.0000000002356 0.68599 10.4072
446 2CJW GDP 0.00000000006555 0.7055 10.4167
447 1ZIN AP5 0.001417 0.46569 10.4326
448 1A4R GDP 0.000000001106 0.71233 10.4712
449 1A4R GNH 0.000000002205 0.69511 10.4712
450 2NGR GDP 0.00000001975 0.62271 10.4712
451 1GRN GDP 0.00000015 0.61342 10.4712
452 4ITR GDP 0.0000002872 0.60404 10.4712
453 1GRN AF3 0.0003039 0.42959 10.4712
454 2NGR AF3 0.0003413 0.42814 10.4712
455 2UZI GTP 0.00000000006367 0.78639 10.5769
456 1IBR GNP 0.0000000002249 0.76427 10.6481
457 5BXQ GDP 0.0000000001862 0.7069 10.6481
458 2A9K GDP 0.000000005318 0.67807 10.6952
459 5N69 ADP 0.0003116 0.46311 11.0553
460 4H1V GNP 0.00000429 0.54852 11.1111
461 4RZ3 ADP 0.0003203 0.46503 11.1864
462 5GJC ATP 0.00007263 0.50986 11.1959
463 3GJ7 GDP 0.0000000002096 0.68808 11.2245
464 5DI3 GNP 0.00000000002084 0.69863 11.3514
465 5J1S ATP 0.0002811 0.41757 11.3821
466 1UAD GNP 0.0000000001942 0.76407 11.4286
467 1ZC3 GNP 0.0000000002295 0.76387 11.4286
468 2QZ4 ADP 0.0001916 0.46508 11.4504
469 3T12 GDP ALF 0.00000000008209 0.67898 11.7647
470 1M7G ADX 0.00003911 0.529 11.8483
471 1M7G AV2 0.00000212 0.51407 11.8483
472 1M7G ADP 0.00008515 0.50968 11.8483
473 1U8Z GDP 0.0000000002153 0.75534 11.9048
474 3GJX GTP 0.0000000003607 0.75478 12.037
475 2A5J GDP 0.000000000584 0.7279 12.0419
476 3CNL GNP 0.0000000002895 0.66412 12.2137
477 2CE7 ADP 0.0002626 0.45865 12.2137
478 2WIC GNP 0.0000000002234 0.75914 12.3596
479 1AZT GSP 0.0000000001292 0.78146 12.7226
480 1CS4 GSP 0.0000000001475 0.60388 12.7226
481 1G6H ADP 0.00001395 0.43352 12.8405
482 4HAT GNP 0.0000000001623 0.77389 12.8571
483 1WA5 GTP 0.0000000002515 0.77348 13.0682
484 1Z2A GDP 0.000000007471 0.58862 13.0952
485 1Z0A GDP 0.0000000002873 0.71377 13.2184
486 1W7J ADP BEF 0.0005704 0.44195 13.245
487 2ORV 4TA 0.007308 0.41492 13.2479
488 1SVI GDP 0.0000000003201 0.66219 13.3333
489 4QRH 0O2 0.002236 0.4315 13.3333
490 4NCN GTP 0.000000000001599 0.85247 13.486
491 2HT6 GDP 0.000000000005157 0.72645 13.486
492 1WDT GTP 0.000000007267 0.63438 13.486
493 3T5G GDP 0.0000000009033 0.69303 13.8158
494 5TB5 GDP 0.000000000584 0.70067 14
495 5TAR GDP 0.000000001558 0.69781 14.1892
496 1XX6 ADP 0.0008159 0.42005 14.6597
497 5UFQ GNP 0.0000000000271 0.64297 14.7541
498 3RAB GNP 0.0000000000251 0.80501 14.7929
499 1G16 GDP 0.000000009262 0.67766 15.2941
500 4TMZ GSP 0.000000000001952 0.84851 15.3623
501 5UWP GNP 0.0000000001688 0.7731 15.3846
502 5UWR GNP 0.0000000001613 0.77096 15.3846
503 5UWI GNP 0.0000000001745 0.76938 15.3846
504 5UWT GNP 0.0000000001782 0.76896 15.3846
505 5UWQ GNP 0.000000000159 0.61202 15.3846
506 5UWJ GNP 0.000000000173 0.61098 15.3846
507 5UWH GNP 0.000000000178 0.61067 15.3846
508 5UWW GNP 0.0000000001867 0.61029 15.3846
509 5UWO GNP 0.0000000001864 0.61021 15.3846
510 5UWU GNP 0.0000000001874 0.61012 15.3846
511 5DI9 GNP 0.0000000002215 0.59608 15.3846
512 5UWS GNP 0.0000000002434 0.5953 15.3846
513 1G7S GDP 0.000000000003078 0.84553 15.5216
514 4ZKD GDP 0.00000000001846 0.81454 15.5216
515 1DAR GDP 0.00000000002545 0.72389 15.5216
516 3EC1 GDP 0.000000000223 0.70234 15.5216
517 2ODE ALF GDP 0.0000000004416 0.75654 15.6028
518 4YMU ATP 0.0001523 0.50119 15.8333
519 1W4R TTP 0.001327 0.4524 15.8974
520 4B47 GDP 0.0000000000007502 0.75935 15.978
521 1F6B GDP 0.00000000022 0.70399 16.1616
522 2JLR ANP 0.0005085 0.45369 16.285
523 2WHX ADP 0.00003141 0.4471 16.285
524 1UPT GTP 0.00000000009986 0.76693 16.6667
525 2OM2 GDP 0.00000001025 0.61265 16.6667
526 3A1S GDP 0.00000012 0.59551 17.0543
527 3EWA ANP 0.0001696 0.44909 17.3913
528 1CXZ GSP 0.0000000002171 0.75163 17.4419
529 3W5J GDP 0.00000001453 0.54774 17.5573
530 1KSH GDP 0.00000000000623 0.8175 18.2796
531 1NRJ GTP 0.0000000005396 0.73008 18.3486
532 3WYG GTP 0.0000000004344 0.75401 18.4211
533 3BC1 GNP 0.00000000004292 0.79428 18.4615
534 1NN5 ANP 0.0002687 0.48959 18.6047
535 5WDR GNP 0.0000000001219 0.77659 18.7134
536 4CVN ADP 0.00001963 0.46777 18.8482
537 4KVG GTP 0.00000000007749 0.78246 19.0476
538 1MKY GDP 0.000000000003045 0.75556 19.5929
539 1ZD9 GDP 0.000000007416 0.6323 19.6809
540 4R98 GNH 0.00000001229 0.62138 19.9262
541 1GUA GNP 0.00000000008196 0.61797 21.5569
542 1LFD GNP 0.00000000002383 0.80606 21.8391
543 1Z0J GTP 0.00000000003136 0.80389 22.0339
544 2W83 GTP 0.00000000002087 0.80157 22.0779
545 3DOE GTP 0.00000000000172 0.85102 23.4375
546 1X1R GDP 0.000000001588 0.72498 23.5955
547 4KAX GTP 0.00000000001026 0.81177 25.4658
548 2WJG GDP 0.00000000009087 0.79081 26.0638
549 3PQC GDP 0.00000004562 0.62056 26.1538
550 3CH5 GDP 0.0000000001356 0.71284 28.8462
551 2WJH GDP 0.0000000001104 0.71759 29.5181
552 2WJH FLC 0.0000002197 0.59218 29.5181
553 5FG3 GDP 0.000000000001018 0.75372 29.771
554 4HDQ GNP 0.0000000003274 0.75673 30.7692
555 1FQJ GDP 0.000000008966 0.58633 30.9524
556 1FQJ ALF 0.000009961 0.5744 30.9524
557 5DIF GNP 0.0000000001345 0.61404 31.5789
558 4RD0 GDP 0.0000000000000232 0.93184 35.8779
559 2QN6 GDP 0.0000000000001831 0.78116 36.1323
560 2VOH CIT 0.01033 0.42684 42.3077
561 1KK1 GNP 0.0000000000001463 0.78263 42.4936
562 1Y3A GDP 0.00000001972 0.66584 50
Pocket No.: 3; Query (leader) PDB : 2BVN; Ligand: GNP; Similar sites found: 1
This union binding pocket(no: 3) in the query (biounit: 2bvn.bio1) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4M7V RAR 0.02119 0.41311 1.71429
Pocket No.: 4; Query (leader) PDB : 2BVN; Ligand: ENX; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2bvn.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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