Receptor
PDB id Resolution Class Description Source Keywords
2C04 1.15 Å NON-ENZYME: SIGNAL_HORMONE GMPPCP COMPLEX OF SRP GTPASE FFH NG DOMAIN AT ULTRA-HIGH RESOLUTION THERMUS AQUATICUS GMPPNP GTP-BINDING RNA-BINDING SIGNALING PROTEIN SRP SRNUCLEOTIDE-BINDING SIGNAL PROTEIN
Ref.: NUCLEOTIDE-BINDING FLEXIBILITY IN ULTRAHIGH-RESOLUTION STRUCTURES OF THE SRP GTPASE FFH ACTA CRYSTALLOGR.,SECT.D V. 64 1043 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CA A:1299;
A:1300;
Part of Protein;
Part of Protein;
none;
none;
submit data
40.078 Ca [Ca+2...
GCP A:1298;
B:1297;
Valid;
Valid;
none;
none;
submit data
521.208 C11 H18 N5 O13 P3 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2C04 1.15 Å NON-ENZYME: SIGNAL_HORMONE GMPPCP COMPLEX OF SRP GTPASE FFH NG DOMAIN AT ULTRA-HIGH RESOLUTION THERMUS AQUATICUS GMPPNP GTP-BINDING RNA-BINDING SIGNALING PROTEIN SRP SRNUCLEOTIDE-BINDING SIGNAL PROTEIN
Ref.: NUCLEOTIDE-BINDING FLEXIBILITY IN ULTRAHIGH-RESOLUTION STRUCTURES OF THE SRP GTPASE FFH ACTA CRYSTALLOGR.,SECT.D V. 64 1043 2008
Members (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 263 families.
1 1O87 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2NG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1NG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 2C03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1JPJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 2C04 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
7 1JPN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 196 families.
1 1O87 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2NG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1NG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 2C03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1JPJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 2C04 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
7 1JPN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 171 families.
1 1O87 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 2NG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1NG1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 2C03 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1JPJ - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 2C04 - GCP C11 H18 N5 O13 P3 c1nc2c(n1[....
7 1JPN - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
8 5L3V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GCP; Similar ligands found: 136
No: Ligand ECFP6 Tc MDL keys Tc
1 GCP 1 1
2 GP3 0.8375 0.948718
3 GDP 0.82716 0.973684
4 GNH 0.817073 0.961039
5 GP2 0.804878 0.987013
6 GTP 0.797619 0.973684
7 G1R 0.788235 0.961039
8 GSP 0.77907 0.925
9 GNP 0.77907 0.948718
10 5GP 0.765432 0.960526
11 G 0.765432 0.960526
12 G2P 0.758621 0.987013
13 GMV 0.755814 0.948718
14 G2R 0.736264 0.961538
15 Y9Z 0.715789 0.903614
16 GDP MG 0.704545 0.9
17 GAV 0.703297 0.936709
18 G3A 0.701031 0.948718
19 GDC 0.697917 0.936709
20 GDD 0.697917 0.936709
21 GKE 0.697917 0.936709
22 GDP BEF 0.696629 0.878049
23 ALF 5GP 0.696629 0.86747
24 G5P 0.693878 0.948718
25 GPG 0.691489 0.936709
26 GDR 0.690722 0.936709
27 GTG 0.690722 0.91358
28 GFB 0.690722 0.936709
29 GDP AF3 0.688172 0.86747
30 YGP 0.6875 0.879518
31 GCP G 0.684783 0.935897
32 6CK 0.683673 0.91358
33 GTP MG 0.673913 0.9
34 BEF GDP 0.673913 0.86747
35 GKD 0.67 0.936709
36 JB2 0.67 0.936709
37 GDX 0.663366 0.948718
38 GPD 0.663366 0.925926
39 GDP ALF 0.652632 0.86747
40 JB3 0.632075 0.925
41 GMP 0.62963 0.857143
42 NGD 0.626168 0.936709
43 G G 0.616162 0.911392
44 G3D 0.610526 0.960526
45 2MD 0.609091 0.870588
46 G4P 0.597938 0.960526
47 U2G 0.59633 0.91358
48 FEG 0.59633 0.880952
49 GDP 7MG 0.596154 0.888889
50 CAG 0.59292 0.860465
51 MGD 0.59292 0.870588
52 ZGP 0.590909 0.870588
53 0O2 0.59 0.960526
54 CG2 0.585586 0.91358
55 PGD 0.57265 0.902439
56 MD1 0.57265 0.892857
57 3GP 0.566667 0.922078
58 TPG 0.563025 0.842697
59 DBG 0.563025 0.925
60 FE9 0.550847 0.760417
61 ACP 0.548387 0.922078
62 GH3 0.54 0.973684
63 I2C FE2 CMO CMO 0.533898 0.791209
64 2GP 0.532609 0.935065
65 G4M 0.53125 0.860465
66 U A G G 0.529915 0.911392
67 GPX 0.529412 0.922078
68 DGI 0.525773 0.924051
69 G A A A 0.521368 0.9
70 IDP 0.520833 0.947368
71 DGT 0.52 0.924051
72 P1G 0.510417 0.873418
73 G1G 0.504132 0.902439
74 BGO 0.5 0.901235
75 G1R G1R 0.5 0.901235
76 PGD O 0.496 0.831461
77 ACQ 0.494949 0.922078
78 G G U 0.491071 0.911392
79 P2G 0.489583 0.860759
80 GGM 0.487395 0.879518
81 MGP 0.485149 0.936709
82 6G0 0.480392 0.936709
83 DG 0.479167 0.911392
84 DGP 0.479167 0.911392
85 GPC 0.47541 0.858824
86 G C 0.475 0.878049
87 4TC 0.470085 0.876543
88 IMP 0.46875 0.934211
89 GTA 0.464912 0.91358
90 G2Q 0.453704 0.961538
91 A2D 0.452632 0.871795
92 G G G C 0.452381 0.890244
93 G7M 0.44898 0.924051
94 APC G U 0.448 0.8875
95 U G A 0.445255 0.86747
96 SGP 0.444444 0.807229
97 BA3 0.443299 0.871795
98 G G G RPC 0.439024 0.853659
99 B4P 0.438776 0.871795
100 ADP 0.438776 0.896104
101 AP5 0.438776 0.871795
102 A G C C 0.4375 0.888889
103 ANP 0.436893 0.873418
104 G C C C 0.435115 0.901235
105 AN2 0.434343 0.884615
106 M33 0.43 0.860759
107 A12 0.428571 0.910256
108 AP2 0.428571 0.910256
109 A G U 0.427536 0.86747
110 PCG 0.427184 0.909091
111 35G 0.427184 0.909091
112 C2E 0.427184 0.897436
113 ATP 0.425743 0.896104
114 5GP 5GP 0.423077 0.860759
115 G U34 0.422764 0.86747
116 APR 0.421569 0.871795
117 AQP 0.421569 0.896104
118 AR6 0.421569 0.871795
119 5FA 0.421569 0.896104
120 SAP 0.417476 0.851852
121 AGS 0.417476 0.851852
122 AD9 0.417476 0.873418
123 UP5 0.416667 0.851852
124 CA0 0.415842 0.873418
125 ATF 0.415094 0.8625
126 A1R 0.409091 0.841463
127 01G 0.408696 0.880952
128 APC 0.407767 0.910256
129 DG DG 0.40708 0.86747
130 A4P 0.406504 0.848837
131 UCG 0.406015 0.888889
132 7DD 0.405941 0.883117
133 93A 0.405941 0.813953
134 6AD 0.40566 0.821429
135 ADX 0.401961 0.790698
136 AGO 0.401575 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2C04; Ligand: GCP; Similar sites found: 552
This union binding pocket(no: 1) in the query (biounit: 2c04.bio2) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2Y8E GNP 0.0001382 0.48909 None
2 1U0J ADP 0.0003417 0.42271 None
3 3KDU NKS 0.03195 0.40366 None
4 3COB ADP 0.00002715 0.43689 1.3468
5 2NCD ADP 0.00009953 0.43184 1.3468
6 1W5T ANP 0.00348 0.41889 1.3468
7 1W5T ADP 0.003636 0.41407 1.3468
8 2G77 GDP 0.0001074 0.48077 1.51515
9 2BME GNP 0.00006288 0.50451 1.6129
10 5MZN ADP 0.0008632 0.47279 1.6835
11 4FRZ ADP 0.00008333 0.43249 1.6835
12 3K7M FAD 0.01429 0.4254 1.6835
13 4TMZ GSP 0.00008072 0.49551 1.73913
14 2J0V GDP 0.0002039 0.45208 1.88679
15 1UKZ ADP 0.005275 0.42745 1.97044
16 5M04 GDP 0.000002417 0.50782 2.0202
17 2XXP DSL 0.02441 0.42139 2.0202
18 1XP8 AGS 0.0007525 0.41273 2.0202
19 2FAH GDP 0.00728 0.4009 2.0202
20 3DKP ADP 0.00004234 0.46753 2.04082
21 1S7N COA 0.0008968 0.4449 2.1978
22 2QZ4 ADP 0.002558 0.41123 2.29008
23 1TQ4 GDP 0.000005589 0.54222 2.3569
24 1KK1 GNP 0.000004501 0.49824 2.3569
25 5JBE MAL 0.002291 0.4707 2.3569
26 1Z6T ADP 0.001138 0.43608 2.3569
27 2QEN ADP 0.002039 0.42503 2.3569
28 1J3I NDP 0.02577 0.40231 2.5
29 1J3I WRA 0.02691 0.40231 2.5
30 1H65 GDP 0.0001071 0.48787 2.59259
31 1Z06 GNP 0.00008068 0.49761 2.6455
32 3DEF GDP 0.00003613 0.4945 2.67176
33 1XKV ATP 0.000003952 0.52508 2.6936
34 2RCN GDP 0.000002788 0.51586 2.6936
35 1ZCB GDP 0.00005978 0.50549 2.6936
36 4B47 GDP 0.000005905 0.49465 2.6936
37 4NCN GTP 0.0001079 0.48988 2.6936
38 1OS1 PYR 0.0002004 0.48882 2.6936
39 1OS1 ATP 0.0001843 0.48882 2.6936
40 1G7S GDP 0.00003821 0.48127 2.6936
41 1P72 ADP 0.000623 0.46918 2.6936
42 3ZFD ANP 0.000347 0.44697 2.6936
43 1G6O ADP 0.0003327 0.44677 2.6936
44 4ZG4 VO4 ADP 0.001225 0.44279 2.6936
45 3LRE ADP 0.00001911 0.42758 2.6936
46 3KJS NAP 0.005607 0.42234 2.6936
47 1BG2 ADP 0.00005029 0.41453 2.6936
48 2YHW BM3 0.009582 0.4129 2.6936
49 5WRI A3P 0.007028 0.40717 2.6936
50 5WRJ A3P 0.008831 0.40605 2.6936
51 3KJS DQ1 0.02267 0.40591 2.6936
52 1PN0 FAD 0.02976 0.40518 2.6936
53 1PN0 IPH 0.03084 0.40518 2.6936
54 2X7I CIT 0.002614 0.40129 2.6936
55 1Q20 PLO 0.01945 0.40098 2.6936
56 1KY3 GDP 0.00002358 0.5027 2.74725
57 4U5X GNP 0.0004685 0.45517 2.80899
58 3AB3 GDP 0.00004555 0.50202 2.84553
59 2FFQ GSP 0.00006411 0.50608 2.92398
60 3CX8 GSP 0.0000347 0.52197 2.95567
61 3T1O GDP 0.00002178 0.49648 3.0303
62 5FG3 GDP 0.00002216 0.47828 3.0303
63 2DPY ADP 0.00004415 0.45289 3.0303
64 4IHQ ADP 0.00006313 0.45222 3.0303
65 1E2K TMC 0.002964 0.44616 3.0303
66 1RRC ADP 0.00001293 0.43828 3.0303
67 1IN4 ADP 0.001676 0.43087 3.0303
68 2Z7I 742 0.03184 0.41493 3.0303
69 3REF GDP 0.0004707 0.45934 3.09278
70 3H86 AP5 0.0004121 0.48035 3.125
71 1A4R GNH 0.0003138 0.46047 3.14136
72 1A4R GDP 0.0004227 0.45713 3.14136
73 3R96 ACO 0.002654 0.4462 3.19149
74 3R96 AMP 0.002654 0.4462 3.19149
75 1U70 NDP 0.01945 0.41177 3.22581
76 1U70 MTX 0.01945 0.41177 3.22581
77 5I34 GDP 0.00000008959 0.57921 3.367
78 1SVK ALF GDP 0.00003942 0.52124 3.367
79 2OM2 GDP 0.00003617 0.50644 3.367
80 3WYA GDP 0.00001425 0.49032 3.367
81 3WY9 GDP 0.00001967 0.47876 3.367
82 5LB3 ADP 0.0007897 0.4686 3.367
83 4KBF AMP 0.00002139 0.46565 3.367
84 4ITR GDP 0.0004321 0.45671 3.367
85 5VGR GDP 0.003893 0.41278 3.367
86 5GJC ATP 0.001878 0.40152 3.367
87 2FJU GSP 0.0005814 0.45321 3.37079
88 1P9B GDP 0.000001763 0.55853 3.39367
89 3A1S GDP 0.00005098 0.47709 3.48837
90 1G6H ADP 0.000005037 0.43892 3.50195
91 3PQC GDP 0.0004322 0.44307 3.58974
92 3Q72 GNP 0.00001153 0.48467 3.61446
93 4R98 GNH 0.00004691 0.46887 3.69004
94 1D5C GDP 0.0000663 0.48989 3.7037
95 1K6M AGS 0.000795 0.45117 3.7037
96 1B0U ATP 0.0006495 0.43951 3.7037
97 3DC4 ADP 0.0001278 0.43481 3.7037
98 2CE7 ADP 0.0007953 0.43336 3.7037
99 2C9O ADP 0.002867 0.42261 3.7037
100 2JLR ANP 0.002543 0.41554 3.7037
101 3ICR FAD 0.01479 0.41194 3.7037
102 1G41 ADP 0.002655 0.41116 3.7037
103 3ICS FAD 0.02122 0.40543 3.7037
104 3NTD FAD 0.02138 0.40528 3.7037
105 3NT6 FAD 0.02201 0.40467 3.7037
106 3NTA FAD 0.02316 0.40361 3.7037
107 2WIC GNP 0.000008181 0.50434 3.74532
108 4YMU ATP 0.0001569 0.50309 3.75
109 1YZN GNP 0.00005707 0.50837 3.78378
110 2W2X GSP 0.0006568 0.45087 3.78378
111 4WZ6 ATP 0.0002234 0.50669 3.7931
112 5UWP GNP 0.00003312 0.52102 3.79747
113 5UWR GNP 0.000035 0.51799 3.79747
114 5UWT GNP 0.0000391 0.51581 3.79747
115 5UWI GNP 0.00004364 0.51365 3.79747
116 5UWO GNP 0.00002951 0.45015 3.79747
117 5UWQ GNP 0.0000394 0.44679 3.79747
118 5UWU GNP 0.00004028 0.44546 3.79747
119 5DHF GNP 0.00003719 0.44528 3.79747
120 5DIF GNP 0.00003851 0.44525 3.79747
121 5UWH GNP 0.00003626 0.4452 3.79747
122 5UWW GNP 0.00004395 0.44339 3.79747
123 5UWJ GNP 0.00006191 0.43926 3.79747
124 5DI9 GNP 0.00004298 0.4369 3.79747
125 5UWS GNP 0.00004565 0.4366 3.79747
126 1NF3 GNP 0.0006973 0.40837 3.90625
127 4KM2 ATR 0.02411 0.40181 3.91061
128 4KM2 TOP 0.02525 0.40181 3.91061
129 1RYH GNP 0.000238 0.45526 3.94089
130 4YDS ATP 0.0007619 0.47553 3.94737
131 4M9Q GNP 0.000008029 0.53781 3.96476
132 2CHG ANP 0.002526 0.42098 3.9823
133 4ZNL BEF ADP 0.0002761 0.44459 4.0146
134 4P32 ADP 0.001763 0.43387 4.01606
135 1DAK DPU 0.002979 0.44817 4.01786
136 1F6B GDP 0.000001004 0.54054 4.0404
137 2I4I AMP 0.000008087 0.52971 4.0404
138 1AZT GSP 0.00006452 0.50966 4.0404
139 2ZPA ADP 0.0001141 0.48207 4.0404
140 2BIF SIN 0.001588 0.46228 4.0404
141 2BIF ANP 0.0009409 0.46228 4.0404
142 1YTM ATP 0.0004144 0.4597 4.0404
143 4XGU ADP 0.000428 0.45459 4.0404
144 4R43 GDP 0.001266 0.45303 4.0404
145 1F9V ADP 0.00002053 0.45096 4.0404
146 5HR5 ADP 0.0007272 0.44456 4.0404
147 5KSZ GCP 0.001252 0.44324 4.0404
148 2OBM ADP 0.00005055 0.4262 4.0404
149 3NHB ADP 0.00009143 0.42485 4.0404
150 4IOK ADP 0.006304 0.41721 4.0404
151 1SQ5 ADP 0.001376 0.4169 4.0404
152 4IOK XPO 0.005778 0.41434 4.0404
153 2Y65 ADP 0.000147 0.41306 4.0404
154 4HSE ADP 0.002317 0.40616 4.0404
155 1D2N ANP 0.001228 0.43887 4.04412
156 2V2V V12 0.0126 0.41819 4.05904
157 3GJ3 GDP 0.000008279 0.49988 4.0724
158 3GJ8 GDP 0.00001348 0.49876 4.0724
159 3GJ5 GDP 0.00001581 0.49623 4.0724
160 3GJ0 GDP 0.00001245 0.49114 4.0724
161 3GJ4 GDP 0.0000161 0.4844 4.0724
162 5L2J 70E 0.04517 0.40659 4.08163
163 1W4R TTP 0.01343 0.4022 4.10256
164 4PX9 ADP 0.00001826 0.47255 4.10959
165 1R2Q GNP 0.00003631 0.52955 4.11765
166 1IBR GNP 0.00004794 0.5118 4.16667
167 4NE2 SH2 0.005994 0.42838 4.19162
168 4NE2 ADP 0.005349 0.42838 4.19162
169 4TMK T5A 0.005701 0.42588 4.22535
170 1M7G ADX 0.0009763 0.45871 4.2654
171 1M7G AV2 0.00005657 0.45678 4.2654
172 1M7G ADP 0.002593 0.43631 4.2654
173 3EC1 GDP 0.000004262 0.51825 4.3771
174 1DAR GDP 0.000003866 0.51057 4.3771
175 1TAD GDP 0.00007238 0.50738 4.3771
176 2XTZ GSP 0.0000547 0.50724 4.3771
177 1FQK GDP 0.0000576 0.50205 4.3771
178 2B8W ALF 5GP 0.003789 0.42258 4.3771
179 1TAD ALF 0.00007238 0.42252 4.3771
180 1T5C ADP 0.00005738 0.4132 4.3771
181 4GBM A3P 0.00662 0.41004 4.3771
182 1NY5 ADP 0.006056 0.40439 4.3771
183 3RC3 ANP 0.001004 0.40206 4.3771
184 1AKY AP5 0.01248 0.41443 4.54545
185 3BOS CDP 0.002322 0.40127 4.54545
186 3RG9 NDP 0.01735 0.40659 4.58333
187 3RG9 WRA 0.02007 0.40659 4.58333
188 1VHT BA3 0.0005221 0.43916 4.58716
189 1QF5 GDP 0.00002311 0.55745 4.7138
190 1WDT GTP 0.000008551 0.53143 4.7138
191 4LYA ATP 0.0002894 0.47783 4.7138
192 1QF5 RPL 0.01035 0.45556 4.7138
193 4PFO ADP 0.0008496 0.45352 4.7138
194 3QKT ANP 0.001344 0.4428 4.7138
195 2FSH ANP 0.001063 0.40936 4.7138
196 4RZ3 ADP 0.0001568 0.4736 4.74576
197 2X77 GDP 0.000007426 0.50938 4.7619
198 5KUT GDP 0.00006267 0.47261 4.7619
199 1VG8 GNP 0.00002648 0.52348 4.83092
200 1VG0 GDP 0.00001357 0.51294 4.83092
201 2F3R G5P 0.004082 0.43136 4.83092
202 4LY9 1YY 0.02914 0.40715 4.86656
203 4LY9 S6P 0.02714 0.40715 4.86656
204 4WOP CTP 0.0004749 0.43959 4.88889
205 2ZEJ GDP 0.000005428 0.55466 4.8913
206 3B5J 12D 0.0001612 0.42901 4.93827
207 2EFE GNH 0.000007452 0.5238 4.97238
208 4NON GDP 0.00004528 0.51484 5
209 1YZG GDP 0.000001161 0.53783 5.02793
210 2KIN ADP 0.00005033 0.41437 5.04202
211 4PPF FLC 0.000001795 0.62072 5.05051
212 4P4T GDP 0.000003846 0.54665 5.05051
213 2ZR9 DTP 0.00008562 0.45308 5.05051
214 5LTJ ADP 0.0002452 0.44545 5.05051
215 2OZE AGS 0.001019 0.44035 5.05051
216 5IRR GSP 0.0003134 0.43893 5.05051
217 2AWN ADP 0.000001108 0.43791 5.05051
218 2ZFI ADP 0.0004412 0.43114 5.05051
219 4GOX A3P 0.004767 0.41642 5.05051
220 3FVQ ATP 0.005318 0.41075 5.05051
221 3DZD ADP 0.006263 0.40013 5.05051
222 4DKX GDP 0.00001171 0.49382 5.09259
223 3GJ7 GDP 0.00001324 0.49192 5.10204
224 5GVR LMR 0.0000004173 0.41321 5.12821
225 3NKV GNP 0.0001306 0.49019 5.14286
226 4KFU ACP 0.00001282 0.45993 5.18868
227 3DOE GTP 0.00001453 0.52875 5.20833
228 1R0X ATP 0.001555 0.40275 5.24476
229 1M2O GNP 0.00001667 0.5305 5.26316
230 1W7J ADP BEF 0.001819 0.4272 5.29801
231 3Q85 GNP 0.000008887 0.49493 5.32544
232 1CS4 GSP 0.00004615 0.51446 5.33333
233 3SBD GNP 0.001106 0.40297 5.34759
234 1KSH GDP 0.00001625 0.52176 5.37634
235 3CPJ GDP 0.00005352 0.48808 5.38117
236 3GJX GTP 0.00005276 0.50992 5.38721
237 5IRN ADP 0.0005745 0.44318 5.38721
238 4YS0 ADP 0.0009783 0.43894 5.38721
239 1V8K ANP 0.0004403 0.4314 5.38721
240 3W5J GDP 0.00001382 0.44567 5.39216
241 1VG9 GDP 0.000004318 0.51818 5.40541
242 1VG1 GDP 0.000008897 0.50564 5.40541
243 1GOT GDP 0.00006052 0.49888 5.47945
244 2QG6 NMN 0.009492 0.40909 5.52764
245 5MVR ADP 0.0005 0.42717 5.55556
246 1UJ2 ADP 0.006486 0.41518 5.55556
247 1UJ2 C5P 0.00716 0.41323 5.55556
248 2ZTS ADP 0.001448 0.43367 5.57769
249 3E5H GNP 0.00003081 0.51847 5.61798
250 3B7G ANP 0.00004185 0.4762 5.65217
251 1IWE IMP 0.00008011 0.56287 5.72391
252 4OHY ANP 0.002518 0.43056 5.72391
253 2GMV UN8 0.0002679 0.41547 5.72391
254 2CJW GDP 0.00000236 0.52063 5.72917
255 1JJV ATP 0.00003304 0.44523 5.82524
256 3T12 GDP ALF 0.00003657 0.50859 5.88235
257 1YZQ GNP 0.0001017 0.49701 5.88235
258 1T8U UAP SGN IDS SGN 0.009059 0.42309 5.88235
259 4KVG GTP 0.00009099 0.49727 5.95238
260 1Y63 ADP 0.0000295 0.47652 5.97826
261 2QTV GNP 0.00001699 0.52796 5.98802
262 4NU0 AP5 0.006867 0.4267 5.99078
263 3VX3 ADP 0.000134 0.47901 6.04839
264 4YC7 GNP 0.0005621 0.45592 6.06061
265 5K5Z ANP 0.0004417 0.41862 6.06061
266 2IS6 ADP 0.0009879 0.41745 6.06061
267 2D7D ADP 0.001163 0.41098 6.06061
268 3T5G GDP 0.00004499 0.48486 6.07735
269 3EEL 53T 0.02339 0.40525 6.1674
270 1QF9 C5P 0.0086 0.421 6.18557
271 2BEK ATP 0.001693 0.45541 6.22568
272 5KSP GDP 0.0004784 0.46764 6.31579
273 2HT6 GDP 0.00000283 0.50856 6.32184
274 1ZD9 GDP 0.000007015 0.5352 6.38298
275 1IHU ADP 0.0000138 0.52974 6.39731
276 1IHU AF3 0.00001744 0.52286 6.39731
277 1X6V ADP 0.0001359 0.49487 6.39731
278 3VMF GTP 0.0001284 0.49053 6.39731
279 1YQT ADP 0.00004755 0.4399 6.39731
280 3EWA ANP 0.0004817 0.42838 6.39731
281 4YSX FAD 0.0103 0.42239 6.41026
282 4QOS ADP 0.001361 0.42128 6.41509
283 1ZJ6 G3D 0.000002056 0.52914 6.41711
284 4V0K GDP 0.000006314 0.54725 6.50888
285 1YVD GNP 0.00003185 0.51783 6.50888
286 3AQ4 GDP 0.0000009936 0.54112 6.52174
287 4HDQ GNP 0.0001229 0.49327 6.58683
288 4HDO GNP 0.0001312 0.492 6.58683
289 2IXE ATP 0.002907 0.42422 6.64207
290 3H4S ADP 0.00005099 0.42952 6.66667
291 2YOH WMJ 0.005202 0.42773 6.66667
292 3KJI ADP 0.000008657 0.5198 6.69291
293 2VB6 ADP BEF 0.0004842 0.46079 6.71141
294 4RD0 GDP 0.00007042 0.49596 6.73401
295 2QN6 GDP 0.000008708 0.48964 6.73401
296 1GOJ ADP 0.0000255 0.4234 6.73401
297 4PJ3 ANP 0.004339 0.41455 6.73401
298 5IFS ADP 0.001602 0.41948 6.75105
299 2CBZ ATP 0.00006446 0.40677 6.75105
300 1S8F GDP 0.0000746 0.50497 6.77966
301 3PCR GTP 0.000005319 0.54822 6.79012
302 4PC3 GDP 0.00001182 0.52891 6.85279
303 4G5G GDP 0.000009675 0.49551 6.85279
304 5JBQ GDP 0.000009842 0.49503 6.85279
305 4P3Y GDP 0.000006457 0.49462 6.85279
306 3U6K GDP 0.00001559 0.48822 6.85279
307 3U6B GDP 0.00001029 0.48751 6.85279
308 2A5F GTP 0.00001091 0.5366 6.85714
309 2BVN GNP 0.00001903 0.50683 6.87023
310 1D8T GDP 0.000006992 0.50051 6.87023
311 1NRJ GTP 0.000007165 0.53746 6.88073
312 5HCN GCP 0.000005417 0.55856 6.89655
313 3Q9L ATP 0.000286 0.46222 6.92308
314 4YLG GDP 0.000005856 0.53582 6.93642
315 3TMK T5A 0.00418 0.42681 6.94444
316 1NN5 ANP 0.00506 0.42573 6.97674
317 1UPT GTP 0.000003427 0.55423 7.01754
318 5EE5 GTP 0.000005108 0.54653 7.04225
319 4KAX GTP 0.000007628 0.5388 7.10059
320 1FQJ GDP 0.00005768 0.50203 7.14286
321 1O3Y GTP 0.000006453 0.54448 7.22892
322 2J59 GTP 0.00001057 0.53491 7.22892
323 2RGX AP5 0.0112 0.42064 7.28155
324 1S9D GDP 0.000001819 0.53083 7.31707
325 1RE0 GDP 0.000001373 0.51749 7.31707
326 4BQS K2Q 0.0001494 0.50234 7.38636
327 4BQS ADP 0.0001494 0.50234 7.38636
328 3N5C GDP 0.000001733 0.52261 7.40741
329 5KDO GDP 0.00003888 0.48071 7.40741
330 4XTR ATP 0.0003353 0.46791 7.40741
331 4XTR ADP 0.0003087 0.46312 7.40741
332 2FNA ADP 0.002582 0.42651 7.40741
333 4XVU ATP 0.0004529 0.42546 7.40741
334 2WOJ ADP ALF 0.0001852 0.42411 7.40741
335 2GK6 ADP 0.0004318 0.41858 7.40741
336 4JLV ADP 0.00009078 0.44378 7.43494
337 4QM7 GTP 0.0001474 0.44283 7.60234
338 5H56 TYD 0.0004221 0.47396 7.69231
339 5H56 ADP 0.0004221 0.47396 7.69231
340 2XAU ADP 0.0001492 0.45949 7.74411
341 5N69 ADP 0.002822 0.42289 7.74411
342 3P4X ADP 0.00001411 0.47715 7.74818
343 1N62 MCN 0.01237 0.4146 7.83133
344 3KV8 FAH 0.04168 0.40482 7.91367
345 2F9L GDP 0.00005854 0.50174 8.0402
346 2HCJ GDP 0.00001042 0.48798 8.0597
347 5GOE GDP 0.000008902 0.54124 8.08081
348 1MKY GDP 0.000006406 0.50379 8.08081
349 3WXM GTP 0.00006537 0.50374 8.08081
350 5FTB ANP 0.0015 0.43966 8.08081
351 5FHD ADP ALF 0.001654 0.41486 8.08081
352 3TBK ANP 0.0009557 0.40149 8.08081
353 3BFV ADP 0.000003475 0.57573 8.11808
354 1Z83 AP5 0.005637 0.4261 8.16327
355 3IUY AMP 0.0000303 0.47269 8.33333
356 1OIX GDP 0.00003764 0.51456 8.37696
357 1OIV GDP 0.0001235 0.49128 8.37696
358 1JWY GDP 0.000003787 0.53562 8.41751
359 3T34 GDP 0.00002124 0.52139 8.41751
360 2WKQ GTP 0.001074 0.44534 8.41751
361 2VVG ADP 0.00003484 0.41997 8.41751
362 1JWY ADP 0.00196 0.40901 8.41751
363 2PL3 ADP 0.00004898 0.45733 8.47458
364 4D81 ADP 0.002612 0.4153 8.48057
365 4BAS GNP 0.000009709 0.53415 8.54271
366 5DI3 GNP 0.000008816 0.49935 8.64865
367 3TK1 GDP 0.000001939 0.50869 8.75421
368 1SKQ GDP 0.000004961 0.49651 8.75421
369 4AG5 ADP 0.000003576 0.47626 8.75421
370 1W0J ADP 0.0003634 0.45306 8.75421
371 4KVA GTP 0.00306 0.44551 8.75421
372 5I0H ADP BEF 0.001327 0.43739 8.75421
373 1SVM ATP 0.008823 0.43016 8.75421
374 2CK3 ADP 0.003544 0.42218 8.75421
375 1W0J ADP BEF 0.00566 0.40766 8.75421
376 2CK3 ANP 0.006123 0.40616 8.75421
377 5JCZ GDP 0.0000609 0.48262 8.93855
378 2EW1 GNP 0.00007829 0.4961 8.95522
379 4LX0 BEF GDP 0.00006902 0.50463 9.03955
380 2WJG GDP 0.00001398 0.48985 9.04255
381 2C78 GNP 0.00001723 0.52309 9.09091
382 2C77 GNP 0.00005381 0.49882 9.09091
383 4IEE AGS 0.0002726 0.42667 9.09091
384 3RLF ANP 0.005381 0.41407 9.09091
385 1JI0 ATP 0.00009695 0.43381 9.16667
386 2D2F ADP 0.00002389 0.40792 9.2
387 4C4P GNP 0.00009853 0.49763 9.24856
388 2HV8 GTP 0.0001055 0.49437 9.30233
389 1F2U ATP 0.001397 0.44544 9.39597
390 1D2E GDP 0.00004659 0.49053 9.42761
391 3V2U ATP 0.008298 0.40396 9.42761
392 1DR1 NAP 0.02039 0.40529 9.52381
393 2D7C GTP 0.00006577 0.50362 9.58084
394 2OFW ADX 0.00004359 0.53172 9.61539
395 4MKF AP5 0.009568 0.42295 9.67742
396 3QF7 ANP 0.002146 0.42617 9.76431
397 2VF7 ADP 0.0008686 0.42475 9.76431
398 2NGR GDP 0.0004791 0.43598 9.82906
399 2ODE ALF GDP 0.00003869 0.51981 9.92908
400 1FP6 ADP 0.0001327 0.4698 10.0346
401 5TSH ANP 0.00006506 0.46054 10.101
402 5TSH ADP 0.00002785 0.44511 10.101
403 2WHX ADP 0.0003602 0.40799 10.101
404 4MKG AP5 0.01186 0.4175 10.1382
405 2WJH GDP 0.00001694 0.49593 10.241
406 2WJH FLC 0.0001243 0.46528 10.241
407 3BC1 GNP 0.00005857 0.50589 10.2564
408 3RWO GDP 0.00007548 0.50093 10.2703
409 1KO8 6PG 0.0007657 0.44581 10.2857
410 2WMO GTP 0.0002099 0.45664 10.5263
411 2V7Q ATP 0.0002128 0.45754 10.6061
412 2PEZ DAT 0.0001504 0.49775 10.6145
413 5X40 ACP 0.002073 0.43258 10.6164
414 3CNL GNP 0.000004094 0.49864 10.687
415 4ZKD GDP 0.00001927 0.52973 10.7744
416 3WYF GTP 0.00003301 0.52109 10.7744
417 4HAT GNP 0.00003856 0.51802 10.7744
418 3WYG GTP 0.00004118 0.51672 10.7744
419 1NJF AGS 0.0008368 0.44825 10.8
420 1NJF ADP 0.0007189 0.44701 10.8
421 4DID GDP 0.0001729 0.45422 10.8808
422 2PZE ATP 0.00005325 0.42394 10.917
423 4ZI2 GNP 0.00001355 0.49103 11.0526
424 4GOJ GNP 0.00001025 0.53311 11.1111
425 3EZ2 ADP 0.0003506 0.42623 11.1111
426 1GRN GDP 0.001228 0.43464 11.33
427 4R2I ANP 0.00001586 0.56041 11.4286
428 2Q2Y ADP 0.004364 0.43818 11.4478
429 2Q2Y MKR 0.004159 0.4381 11.4478
430 2QV7 ADP 0.00387 0.40848 11.4478
431 3HRD MCN 0.01793 0.40485 11.4478
432 2XTN GTP 0.00001848 0.52409 11.5385
433 5BQ5 ADP BEF 0.001114 0.44556 11.6402
434 4V03 ADP 0.0000779 0.47219 11.6732
435 3IO3 ADP 0.0003123 0.46289 11.7816
436 3FWY ADP 0.0001943 0.46954 11.7845
437 1L2T ATP 0.003765 0.42271 11.9149
438 5G41 AP5 0.006348 0.43531 12.1076
439 4J0Q GDP 0.000002785 0.50613 12.1212
440 1LVG ADP 0.00002664 0.45634 12.1212
441 5UQW GDP 0.00008569 0.49644 12.1693
442 3A4M ADP 0.00002612 0.45762 12.3077
443 1GUA GNP 0.00009492 0.49836 12.3457
444 1S3G AP5 0.003465 0.44294 12.4424
445 1ZIN AP5 0.005703 0.43265 12.4424
446 4BFW ZVW 0.01562 0.41179 12.4579
447 3FB4 AP5 0.005228 0.43445 12.5
448 3FKQ ATP 0.001029 0.43798 12.8686
449 2W83 GTP 0.00001038 0.53527 12.987
450 1JJ7 ADP 0.000005565 0.43901 13.0769
451 3SFV GDP 0.0001194 0.48355 13.1313
452 2C5L GTP 0.0001851 0.48522 13.2948
453 1SVI GDP 0.00004879 0.46717 13.3333
454 5XCO GDP 0.00008341 0.48228 13.4503
455 5O2T GSP 0.000116 0.43282 13.6095
456 5J1J ANP 0.0001551 0.44273 13.6842
457 5E95 GDP 0.0001699 0.47208 13.6905
458 3X1Z GNP 0.0001425 0.42453 13.7725
459 4LC1 GDP 0.000004641 0.50808 13.8047
460 1G7C 5GP 0.000005078 0.50543 13.8298
461 5UFQ GNP 0.00002599 0.5218 13.8554
462 1CLU DBG 0.0002007 0.50409 13.8554
463 2UZI GTP 0.00007161 0.50196 13.8554
464 1WQ1 GDP 0.0001757 0.48043 13.8554
465 3DDC GNP 0.0002517 0.47917 13.8554
466 3KUD GDP 0.0001925 0.4744 13.8554
467 3FYH ADP 0.002375 0.4317 14.1414
468 1XMV ADP 0.0005497 0.43131 14.1414
469 1OXV ANP 0.0003824 0.42025 14.1414
470 3RAB GNP 0.0001488 0.48764 14.2012
471 1WA5 GTP 0.00009238 0.50593 14.4781
472 5JCP GDP ALF 0.0008519 0.44156 14.4781
473 5SZH GNP 0.00007627 0.50267 14.7783
474 4H1V GNP 0.000003396 0.54613 15.1515
475 3TKL GTP 0.00006386 0.50217 15.3061
476 4E03 ADP 0.000003602 0.5176 15.534
477 1YRB GDP 0.000002452 0.54423 15.6489
478 1R4A GNP 0.000006255 0.54744 15.6863
479 2GJ8 ALF GDP 0.00007019 0.4394 15.6977
480 4DCT GDP 0.00009312 0.467 15.8249
481 3ZIA ADP 0.0005752 0.44446 15.873
482 3ZIA ATP 0.000514 0.43527 15.873
483 2GDJ ANP 0.001058 0.41927 15.9091
484 4CVN ADP 0.0001271 0.43685 16.0584
485 2A5J GDP 0.00003291 0.49036 16.2304
486 2HF9 GSP 0.0000186 0.51394 16.3717
487 1TU3 GNP 0.00008374 0.4989 16.4557
488 1HTW ADP 0.0005058 0.4344 16.4557
489 1XEX ATP 0.001495 0.44245 16.4835
490 3KTA AP5 0.001053 0.43221 16.4835
491 3UIE ANP 0.00006795 0.47491 16.5
492 4LPS GDP 0.00003158 0.48192 16.5289
493 1B7T ADP 0.002939 0.40856 16.6667
494 1NST A3P 0.00192 0.42617 16.835
495 2QQ0 ANP 0.006488 0.42202 16.8478
496 2QQ0 TMP 0.006689 0.4214 16.8478
497 2QQ0 THM 0.007081 0.41767 16.8478
498 1KK8 BEF ADP 0.0003819 0.45675 16.8831
499 5WDR GNP 0.0001288 0.49235 16.9591
500 4WZA ADP 0.0002323 0.51708 17.1717
501 4WZA ACP 0.0003812 0.5064 17.1717
502 1NVV GNP 0.000184 0.48533 17.1717
503 1NVU GTP 0.0002298 0.48096 17.1717
504 3BER AMP 0.00001563 0.4843 17.2691
505 1KMQ GNP 0.001011 0.4465 17.3913
506 4XOI GTP 0.001052 0.44758 17.7778
507 1Z0A GDP 0.00003568 0.48891 17.8161
508 2W58 ADP 0.00001741 0.42537 17.8218
509 5BXQ GDP 0.000006403 0.51143 18.1102
510 4TTQ ATP 0.0003703 0.43313 18.1395
511 1GP2 GDP 0.0000382 0.51001 18.3099
512 1WF3 GNP 0.00002998 0.52104 19.1919
513 2GCN GDP 0.0007607 0.45009 19.403
514 2GCO GNP 0.0005859 0.44865 19.403
515 3IIJ ADP 0.00002532 0.47736 19.4444
516 3ZQ6 ADP ALF 0.0002288 0.48105 20.0617
517 1Z0K GTP 0.00005906 0.50157 20.2899
518 4U00 ADP 0.000002328 0.44507 21.3115
519 1CR1 TTP 0.00447 0.41408 21.6216
520 4DSU GDP 0.00008239 0.50115 21.6931
521 5TAR GDP 0.00006957 0.49459 22.1622
522 5TB5 GDP 0.00006296 0.47953 22.1622
523 1OW3 GDP 0.002441 0.42163 22.2798
524 3QXC ATP 0.009053 0.4086 22.314
525 4D0G GTP 0.00005787 0.49974 23.1884
526 2XT3 ADP 0.00001845 0.44074 23.2323
527 4D0N GDP 0.00009967 0.45665 23.2432
528 3LXR GDP 0.000309 0.45023 23.2432
529 5HPY GDP 0.001067 0.4373 23.2432
530 1EK0 GNP 0.0001644 0.48568 23.5294
531 2A9K GDP 0.00009922 0.48226 23.5294
532 1CXZ GSP 0.0006668 0.45263 23.6264
533 3ZS9 ADP ALF 0.0002031 0.4834 23.6842
534 4XSH GSP 0.0006806 0.43915 24.0223
535 4OI4 ATP 0.009905 0.4022 24.2424
536 1TX4 ALF GDP 0.002104 0.4323 24.2938
537 1J2J GTP 0.0000127 0.53136 24.4444
538 5XDR ADP 0.0001573 0.49021 24.5791
539 1Z0F GDP 0.00003909 0.4812 24.581
540 4HI0 GDP 0.00001976 0.51802 24.6231
541 1UAD GNP 0.0001545 0.4869 25.1429
542 3MD0 GDP 0.00000154 0.51538 25.2525
543 3MJH GTP 0.00009307 0.49683 26.7857
544 1ZUI SKM 0.001141 0.46101 26.7857
545 1Z08 GNP 0.00006267 0.50042 27.0588
546 3TNF GNP 0.00003416 0.52041 27.5862
547 3QBT GNP 0.00006977 0.50247 27.5862
548 4LHW GNP 0.00009905 0.49561 27.5862
549 1LFD GNP 0.0001296 0.49035 32.1839
550 1Z2A GDP 0.00004889 0.50523 33.3333
551 1Z0J GTP 0.00003186 0.51984 33.8983
552 2BCG GDP 0.00005756 0.49511 35.9223
Pocket No.: 2; Query (leader) PDB : 2C04; Ligand: GCP; Similar sites found: 15
This union binding pocket(no: 2) in the query (biounit: 2c04.bio1) has 22 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2FZH DH1 0.02104 0.40252 0.970874
2 4IDN GNP 0.004521 0.40114 1.6835
3 4WEI GLC GAL 0.006324 0.43156 2.16606
4 1Q9I TEO 0.03408 0.40315 3.0303
5 1Q9I FAD 0.03408 0.40315 3.0303
6 2R4J FAD 0.03105 0.40241 4.0404
7 2R4J 13P 0.03105 0.40241 4.0404
8 1QO8 FAD 0.01036 0.41772 4.3771
9 5E5U MLI 0.0114 0.42128 4.52261
10 1KNR FAD 0.01698 0.40594 4.7138
11 2JAQ DCP 0.005546 0.40656 6.34146
12 2ZE7 DST 0.005935 0.41007 7.90514
13 2PEZ GGZ 0.0001215 0.41171 10.6145
14 4GDX GLU 0.0207 0.40664 12.3077
15 4QRH 0O2 0.003446 0.41178 13.8095
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