Receptor
PDB id Resolution Class Description Source Keywords
2C5B 2.4 Å EC: 2.5.1.63 X-RAY CRYSTAL STRUCTURE OF 5'-FLUORODEOXYADENOSINE SYNTHASE FROM STREPTOMYCES CATTLEYA COMPLEXED WITH 2'DEOXY-5'DEOXY- F LUOROADENOSINE. STREPTOMYCES CATTLEYA TRANSFERASE FLUORINASE 5-prime -FLUORODEOXYADENOSINE SYNTHASE FLA INHIBITOR AZA STREPTOMYCES CATTLEYA SAM ANALOGUE
Ref.: SUBSTRATE SPECIFICITY IN ENZYMATIC FLUORINATION. THE FLUORINASE FROM STREPTOMYCES CATTLEYA ACCEPTS 2'-DEOXYADENOSINE SUBSTRATES. ORG.BIOMOL.CHEM. V. 4 1458 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
5F1 A:500;
B:500;
C:500;
 Valid;
Valid;
Valid;
 none;
none;
none;
 submit data
253.233 C10 H12 F N5 O2 c1nc(...
MET A:600;
B:600;
C:600;
 Valid;
Valid;
Valid;
 none;
none;
none;
 submit data
149.211 C5 H11 N O2 S CSCC[...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2V7T 2.15 Å EC: 2.5.1.63 X-RAY CRYSTAL STRUCTURE OF 5'-FLUORODEOXYADENOSINE SYNTHASE MUTANT COMPLEXED WITH S-ADENOSYL-L-HOMOCYSTEINE AND CHLORID STREPTOMYCES CATTLEYA TRANSFERASE MECHANISM OF FLUORINATION BIOSYNTHETIC PROTEIN
Ref.: MECHANISM OF ENZYMATIC FLUORINATION IN STREPTOMYCES CATTLEYA. J. AM. CHEM. SOC. V. 129 14597 2007
Members (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2V7T Ka = 30200000 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 2CC2 - 5AD C10 H13 N5 O3 C[C@@H]1[C....
3 2CBX - CC5 C9 H11 N5 O3 c1nc(c2c(n....
4 2V7V Ka = 4550000 M^-1 5FD C10 H14 F N5 O3 [H]/N=C/1C....
5 2V7W - 5FD C10 H14 F N5 O3 [H]/N=C/1C....
6 2V7X Ka = 59000 M^-1 MET C5 H11 N O2 S CSCC[C@@H]....
7 5FIU Ka = 2710000 M^-1 Y3J C10 H11 F2 N5 O3 c1nc(c2c(n....
8 2V7U Ka = 800000 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
9 1RQP - SAM C15 H22 N6 O5 S C[S@@+](CC....
10 2C2W - 5CD C10 H12 Cl N5 O3 c1nc(c2c(n....
11 2C5B - MET C5 H11 N O2 S CSCC[C@@H]....
70% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2V7T Ka = 30200000 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 2CC2 - 5AD C10 H13 N5 O3 C[C@@H]1[C....
3 2CBX - CC5 C9 H11 N5 O3 c1nc(c2c(n....
4 2V7V Ka = 4550000 M^-1 5FD C10 H14 F N5 O3 [H]/N=C/1C....
5 2V7W - 5FD C10 H14 F N5 O3 [H]/N=C/1C....
6 2V7X Ka = 59000 M^-1 MET C5 H11 N O2 S CSCC[C@@H]....
7 5FIU Ka = 2710000 M^-1 Y3J C10 H11 F2 N5 O3 c1nc(c2c(n....
8 2V7U Ka = 800000 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
9 1RQP - SAM C15 H22 N6 O5 S C[S@@+](CC....
10 2C2W - 5CD C10 H12 Cl N5 O3 c1nc(c2c(n....
11 2C5B - MET C5 H11 N O2 S CSCC[C@@H]....
12 5B6I - MET C5 H11 N O2 S CSCC[C@@H]....
50% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 223 families.
1 2Q6K - ADN C10 H13 N5 O4 c1nc(c2c(n....
2 6RYZ - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 2Q6O - SAM C15 H22 N6 O5 S C[S@@+](CC....
4 6RZ2 - 5CD C10 H12 Cl N5 O3 c1nc(c2c(n....
5 7CCG - 5CD C10 H12 Cl N5 O3 c1nc(c2c(n....
6 2V7T Ka = 30200000 M^-1 SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 2CC2 - 5AD C10 H13 N5 O3 C[C@@H]1[C....
8 2CBX - CC5 C9 H11 N5 O3 c1nc(c2c(n....
9 2V7V Ka = 4550000 M^-1 5FD C10 H14 F N5 O3 [H]/N=C/1C....
10 2V7W - 5FD C10 H14 F N5 O3 [H]/N=C/1C....
11 2V7X Ka = 59000 M^-1 MET C5 H11 N O2 S CSCC[C@@H]....
12 5FIU Ka = 2710000 M^-1 Y3J C10 H11 F2 N5 O3 c1nc(c2c(n....
13 2V7U Ka = 800000 M^-1 SAM C15 H22 N6 O5 S C[S@@+](CC....
14 1RQP - SAM C15 H22 N6 O5 S C[S@@+](CC....
15 2C2W - 5CD C10 H12 Cl N5 O3 c1nc(c2c(n....
16 2C5B - MET C5 H11 N O2 S CSCC[C@@H]....
17 5B6I - MET C5 H11 N O2 S CSCC[C@@H]....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 5F1; Similar ligands found: 77
No: Ligand ECFP6 Tc MDL keys Tc
1 5F1 1 1
2 3D1 0.789474 0.892308
3 3L1 0.789474 0.892308
4 D5M 0.661765 0.816901
5 DA 0.661765 0.816901
6 AS 0.652174 0.773333
7 DAT 0.6 0.794521
8 DTP 0.56962 0.794521
9 DZ4 0.5625 0.773333
10 101 0.555556 0.767123
11 KF5 0.523077 0.71875
12 3AD 0.522388 0.846154
13 103 0.520548 0.702703
14 MDR 0.507246 0.833333
15 XYA 0.5 0.80597
16 ADN 0.5 0.80597
17 RAB 0.5 0.80597
18 NOC 0.492537 0.746269
19 2FD 0.486111 0.882353
20 5N5 0.485294 0.80597
21 7D7 0.484848 0.80303
22 CC5 0.484848 0.830769
23 A4D 0.478261 0.80597
24 5CD 0.478261 0.846154
25 CL9 0.472222 0.855072
26 5AD 0.469697 0.78125
27 MTA 0.465753 0.782609
28 Y3J 0.463768 0.8125
29 EP4 0.458333 0.760563
30 NWW 0.457143 0.769231
31 3DH 0.453333 0.782609
32 ZDA 0.452381 0.684211
33 M2T 0.452055 0.739726
34 DTA 0.452055 0.797101
35 DDS 0.44186 0.743243
36 ZAS 0.441558 0.774648
37 CPA 0.436893 0.725
38 OVE 0.435897 0.701299
39 2AM 0.434211 0.72973
40 AFX 0.430556 0.704225
41 ARJ 0.430556 0.757576
42 N5O 0.43038 0.797101
43 DSH 0.43038 0.828571
44 NEC 0.43038 0.753623
45 3AM 0.428571 0.716216
46 CUU 0.428571 0.733333
47 DOI 0.426829 0.743243
48 6MA 0.426829 0.780822
49 KL2 0.426667 0.702703
50 ABM 0.425 0.710526
51 45A 0.425 0.710526
52 LMS 0.423077 0.642857
53 A 0.423077 0.72973
54 AMP 0.423077 0.72973
55 A7D 0.421687 0.811594
56 7D5 0.421053 0.72
57 N5A 0.419753 0.794118
58 AMP MG 0.417722 0.739726
59 SRA 0.417722 0.692308
60 6RE 0.417722 0.767123
61 AOC 0.4125 0.782609
62 A3G 0.4125 0.811594
63 2VA 0.411765 0.760563
64 QQX 0.410256 0.675325
65 5AS 0.409639 0.625
66 3AT 0.409091 0.733333
67 J7C 0.407407 0.777778
68 A3N 0.407407 0.771429
69 A2D 0.407407 0.710526
70 ACK 0.405063 0.722222
71 QQY 0.405063 0.684211
72 SP1 0.405063 0.688312
73 RP1 0.405063 0.688312
74 A3S 0.404762 0.823529
75 S4M 0.402439 0.753247
76 GJV 0.402439 0.756757
77 ADX 0.4 0.642857
Ligand no: 2; Ligand: MET; Similar ligands found: 33
No: Ligand ECFP6 Tc MDL keys Tc
1 MED 1 1
2 MET 1 1
3 DBB 0.518519 0.655172
4 ABA 0.518519 0.655172
5 2FM 0.514286 0.666667
6 MF3 0.5 0.647059
7 NVA 0.5 0.758621
8 B3M 0.472222 0.8125
9 HSE 0.466667 0.617647
10 DAB 0.466667 0.636364
11 MHO 0.457143 0.717949
12 SME 0.457143 0.717949
13 HCS 0.451613 0.733333
14 API 0.451613 0.606061
15 CDT 0.447368 0.756757
16 2MM 0.444444 0.657143
17 NLE 0.441176 0.766667
18 ONL 0.441176 0.71875
19 UN1 0.428571 0.606061
20 11C 0.428571 0.606061
21 MSE 0.428571 0.9
22 GLU 0.424242 0.625
23 GGL 0.424242 0.625
24 DGL 0.424242 0.625
25 CBH 0.418605 0.685714
26 ORN 0.411765 0.65625
27 AME 0.410256 0.771429
28 FME 0.410256 0.84375
29 LEU 0.40625 0.666667
30 CYS 0.4 0.666667
31 DCY 0.4 0.666667
32 C2N 0.4 0.633333
33 JM6 0.4 0.7
Similar Ligands (3D)
Ligand no: 1; Ligand: 5F1; Similar ligands found: 463
No: Ligand Similarity coefficient
1 5FD 0.9782
2 GNG 0.9759
3 1DA 0.9702
4 AD3 0.9689
5 HPR 0.9653
6 NOS 0.9622
7 PRH 0.9587
8 UA2 0.9571
9 IMH 0.9567
10 5UD 0.9533
11 FMC 0.9511
12 SCT 0.9493
13 GMP 0.9469
14 TMC 0.9454
15 TBN 0.9454
16 2FA 0.9442
17 MTI 0.9424
18 8OX 0.9421
19 5ID 0.9420
20 CFE 0.9419
21 833 0.9413
22 IMG 0.9411
23 DBM 0.9408
24 3BH 0.9386
25 MTM 0.9385
26 FMB 0.9380
27 MTP 0.9359
28 6MD 0.9357
29 RPP 0.9352
30 2JX 0.9350
31 DCZ 0.9349
32 PUR 0.9345
33 CTN 0.9337
34 C4E 0.9320
35 GA2 0.9318
36 5NB 0.9314
37 8HG 0.9314
38 DCF 0.9310
39 4CN 0.9309
40 FTU 0.9303
41 EKH 0.9295
42 9DI 0.9293
43 BMC 0.9289
44 CDY 0.9281
45 BZM 0.9278
46 MZR 0.9264
47 ZYV 0.9259
48 1Q4 0.9254
49 26A 0.9237
50 H7S 0.9234
51 6CR 0.9233
52 MG7 0.9226
53 FM1 0.9220
54 AVX 0.9218
55 9UL 0.9218
56 5I5 0.9214
57 TAL 0.9214
58 X2M 0.9209
59 4UO 0.9207
60 4G2 0.9205
61 TRP 0.9205
62 NAL 0.9203
63 PE2 0.9200
64 92O 0.9183
65 RFZ 0.9166
66 THU 0.9163
67 EXG 0.9157
68 MTH 0.9153
69 XYP XDN 0.9147
70 XDL XYP 0.9147
71 NXB 0.9144
72 XDN XYP 0.9144
73 XIL 0.9142
74 XYP XYP 0.9142
75 XTS 0.9139
76 FM2 0.9139
77 2P3 0.9136
78 ACE TRP 0.9133
79 4GU 0.9132
80 EAT 0.9123
81 0XR 0.9120
82 CTE 0.9114
83 3Q0 0.9113
84 DTE 0.9111
85 AC2 0.9109
86 P2L 0.9108
87 3RP 0.9107
88 3D8 0.9105
89 0SY 0.9099
90 A4V 0.9099
91 MCF 0.9091
92 B5A 0.9089
93 DBS 0.9077
94 NWQ 0.9075
95 2QU 0.9074
96 TO1 0.9073
97 HO4 0.9069
98 XYP XYS 0.9067
99 0OK 0.9064
100 DIH 0.9059
101 KWB 0.9058
102 DTR 0.9053
103 22L 0.9047
104 TR7 0.9047
105 0GA 0.9042
106 XYS XYP 0.9041
107 NEO 0.9040
108 8DA 0.9037
109 ITW 0.9034
110 XYP XIF 0.9033
111 XIF XYP 0.9033
112 WCU 0.9026
113 EXR 0.9024
114 H4B 0.9019
115 FCW 0.9018
116 NEU 0.9013
117 F40 0.9013
118 QME 0.9008
119 OUA 0.8998
120 BIO 0.8985
121 ETV 0.8981
122 HBI 0.8980
123 JMQ 0.8979
124 Z8B 0.8976
125 13A 0.8975
126 B2L 0.8972
127 I2E 0.8970
128 OLU 0.8969
129 M5H 0.8969
130 KP2 0.8969
131 TIA 0.8968
132 6ZW 0.8966
133 5E4 0.8964
134 II4 0.8963
135 M01 0.8958
136 AOJ 0.8958
137 MBY 0.8955
138 28A 0.8954
139 5E5 0.8951
140 XYS AZI XYS 0.8951
141 ZIQ 0.8949
142 3IL 0.8948
143 DXK 0.8946
144 ZRK 0.8945
145 4AB 0.8936
146 EMU 0.8934
147 MPU 0.8933
148 2J5 0.8932
149 HVE 0.8932
150 9FG 0.8931
151 H75 0.8929
152 RVD 0.8928
153 XYS XYS 0.8927
154 ZEZ 0.8926
155 ZYW 0.8924
156 RVB 0.8924
157 9E3 0.8922
158 2GQ 0.8921
159 M02 0.8921
160 7EH 0.8920
161 NE1 0.8920
162 3IP 0.8919
163 H2B 0.8919
164 0FR 0.8919
165 2L2 0.8918
166 5V7 0.8918
167 EXX 0.8913
168 C2M 0.8912
169 NIY 0.8911
170 Q5M 0.8911
171 16Z 0.8907
172 NQ7 0.8905
173 BC3 0.8903
174 JGB 0.8896
175 2L1 0.8896
176 3SU 0.8894
177 C0H 0.8893
178 CMP 0.8891
179 RVE 0.8887
180 XCG 0.8885
181 B41 0.8885
182 ZSP 0.8884
183 AGV 0.8882
184 RNK 0.8881
185 EV2 0.8873
186 14Z 0.8871
187 9CE 0.8870
188 363 0.8870
189 C4F 0.8868
190 092 0.8865
191 X48 0.8865
192 XYP AHR 0.8861
193 NPX 0.8854
194 IOS 0.8853
195 MXD 0.8853
196 4K2 0.8853
197 G14 0.8851
198 1SF 0.8851
199 7G1 0.8850
200 S0G 0.8848
201 EXL 0.8847
202 848 0.8844
203 CUH 0.8841
204 6J3 0.8839
205 DAH 0.8839
206 6QT 0.8837
207 0J4 0.8836
208 7CI 0.8835
209 JA3 0.8834
210 2UD 0.8833
211 4FF 0.8833
212 IM5 0.8829
213 ZEB 0.8828
214 BBY 0.8826
215 YF3 0.8826
216 88R 0.8826
217 1A5 0.8825
218 JSX 0.8824
219 G30 0.8822
220 2GD 0.8822
221 FY8 0.8822
222 7ZL 0.8822
223 Q4G 0.8821
224 FT6 0.8820
225 STZ 0.8814
226 L3L 0.8814
227 RE4 0.8813
228 VBC 0.8810
229 Q2S 0.8810
230 BB4 0.8810
231 1XS 0.8807
232 25F 0.8807
233 3AK 0.8806
234 96Z 0.8805
235 TDI 0.8804
236 22T 0.8802
237 DS8 0.8800
238 4OG 0.8800
239 PLP 0.8799
240 3WK 0.8797
241 NNR 0.8797
242 7AP 0.8797
243 LL1 0.8796
244 FWD 0.8795
245 CMU 0.8794
246 VCE 0.8794
247 5SJ 0.8793
248 3TC 0.8791
249 JYK 0.8789
250 6J5 0.8787
251 JYW 0.8786
252 LVY 0.8785
253 3WN 0.8784
254 3WO 0.8784
255 GXG 0.8784
256 78U 0.8784
257 G6P 0.8781
258 VJJ 0.8779
259 JOB 0.8778
260 JOV 0.8778
261 RBV 0.8777
262 MIL 0.8775
263 HA6 0.8775
264 0ON 0.8774
265 1FL 0.8772
266 EYY 0.8770
267 W23 0.8769
268 GW3 0.8767
269 4L2 0.8767
270 109 0.8766
271 7L4 0.8765
272 YE7 0.8763
273 S1D 0.8760
274 DFL 0.8760
275 3Y7 0.8759
276 69K 0.8759
277 15Q 0.8758
278 5WN 0.8757
279 9FH 0.8757
280 IOP 0.8754
281 P4L 0.8753
282 GZV 0.8752
283 92G 0.8752
284 1KN 0.8750
285 GFE 0.8749
286 KYN 0.8748
287 BNY 0.8746
288 S7D 0.8745
289 CJZ 0.8744
290 2KU 0.8741
291 LR2 0.8741
292 FUB FUB 0.8740
293 LU2 0.8740
294 5NN 0.8738
295 5AV 0.8736
296 7FZ 0.8736
297 4Z9 0.8735
298 1YO 0.8733
299 AP6 0.8731
300 TCC 0.8731
301 0UL 0.8730
302 ZEA 0.8730
303 6U5 0.8730
304 JO5 0.8729
305 EF2 0.8729
306 ZMG 0.8728
307 D64 0.8727
308 MMS 0.8726
309 TCL 0.8726
310 C09 0.8725
311 Z17 0.8725
312 TMG 0.8725
313 6BK 0.8725
314 2D2 0.8720
315 TIZ 0.8720
316 OA4 0.8720
317 42R 0.8720
318 AWE 0.8719
319 0J2 0.8719
320 ZIP 0.8716
321 FYR 0.8716
322 MFR 0.8716
323 M0N 0.8716
324 BHS 0.8715
325 ID8 0.8714
326 EZN 0.8713
327 TVZ 0.8712
328 ELH 0.8711
329 AMR 0.8710
330 PMP 0.8709
331 3QI 0.8708
332 8D6 0.8706
333 9KZ 0.8705
334 B52 0.8704
335 3IB 0.8704
336 68B 0.8703
337 4NR 0.8702
338 AHR FUB 0.8701
339 NAR 0.8700
340 IAC 0.8700
341 1QV 0.8699
342 CQW 0.8698
343 YOF 0.8697
344 X04 0.8697
345 3WJ 0.8696
346 Q9T 0.8695
347 YIH 0.8694
348 AGI 0.8694
349 IXG 0.8694
350 CWD 0.8693
351 XEV 0.8691
352 5O5 0.8690
353 BPY 0.8689
354 51Y 0.8688
355 A7K 0.8688
356 B21 0.8687
357 NPS 0.8687
358 1KX 0.8685
359 Z21 0.8684
360 LOX XYP 0.8683
361 AV4 0.8682
362 VUP 0.8681
363 TGW 0.8681
364 ZRL 0.8681
365 57D 0.8677
366 78P 0.8675
367 H35 0.8672
368 A4G 0.8672
369 7G0 0.8670
370 AJ4 0.8669
371 5P7 0.8669
372 DHC 0.8668
373 6EL 0.8668
374 DNB 0.8667
375 9JT 0.8666
376 5BX 0.8665
377 CBE 0.8665
378 5S9 0.8664
379 Z15 0.8664
380 C1Y 0.8664
381 D87 0.8663
382 LTN 0.8661
383 PMM 0.8661
384 HLP 0.8657
385 Y70 0.8655
386 6TX 0.8654
387 SGV 0.8654
388 IMK 0.8652
389 9BF 0.8652
390 3VW 0.8650
391 14N 0.8645
392 RVC 0.8640
393 Y0V 0.8639
394 ZZA 0.8638
395 3GX 0.8636
396 IM4 0.8636
397 159 0.8634
398 11X 0.8634
399 5B2 0.8633
400 A45 0.8633
401 MUK 0.8633
402 N1E 0.8633
403 26C 0.8632
404 GJB 0.8632
405 IQW 0.8631
406 PLR 0.8631
407 PZ8 0.8629
408 75G 0.8627
409 RKY 0.8626
410 X29 0.8625
411 47V 0.8624
412 CUQ 0.8622
413 6C9 0.8619
414 Z57 0.8619
415 0OO 0.8619
416 AVA 0.8618
417 X0T 0.8616
418 4AU 0.8615
419 YIP 0.8612
420 7CH 0.8609
421 9PP 0.8608
422 XYP XIM 0.8608
423 F5C 0.8608
424 TH1 0.8607
425 SJK 0.8604
426 2LT 0.8603
427 2JM 0.8599
428 TQ3 0.8599
429 LZ5 0.8598
430 WDW 0.8596
431 F63 0.8594
432 HHV 0.8593
433 FER 0.8588
434 OUG 0.8585
435 MYT 0.8584
436 PQS 0.8581
437 M77 0.8581
438 KCH 0.8579
439 MQU 0.8576
440 LVP 0.8575
441 FB4 0.8572
442 VPU 0.8568
443 4AF 0.8567
444 JY2 0.8564
445 RSV 0.8561
446 A73 0.8560
447 1V1 0.8557
448 54E 0.8550
449 FMQ 0.8550
450 8M5 0.8550
451 H52 0.8545
452 T1N 0.8544
453 TSR 0.8541
454 F02 0.8536
455 QKU 0.8535
456 L21 0.8533
457 6HP 0.8532
458 0X2 0.8532
459 A4N 0.8532
460 DCN 0.8530
461 9F8 0.8528
462 KMP 0.8519
463 5R9 0.8511
Ligand no: 2; Ligand: MET; Similar ligands found: 868
No: Ligand Similarity coefficient
1 AKG 1.0000
2 2CO 0.9906
3 KMT 0.9826
4 MPJ 0.9772
5 LYN 0.9729
6 ONH 0.9693
7 LYS 0.9645
8 DLY 0.9610
9 9ON 0.9607
10 OGA 0.9594
11 CSS 0.9592
12 S2G 0.9571
13 7C3 0.9555
14 2IT 0.9546
15 GLN 0.9528
16 SLZ 0.9527
17 ASP 0.9523
18 HTX 0.9512
19 KQY 0.9511
20 SKJ 0.9499
21 ACA 0.9485
22 HL5 0.9482
23 69O 0.9480
24 DAV 0.9461
25 SHV 0.9458
26 NWH 0.9450
27 LMR 0.9448
28 9X7 0.9448
29 MLT 0.9446
30 6XA 0.9425
31 6NA 0.9424
32 ILE 0.9417
33 AL0 0.9416
34 2HG 0.9410
35 N6C 0.9404
36 HPN 0.9394
37 VAH 0.9387
38 PEL 0.9385
39 ASN 0.9383
40 MPH 0.9372
41 DHR 0.9370
42 LT1 0.9353
43 MD0 0.9345
44 258 0.9342
45 N4B 0.9338
46 NLP 0.9337
47 CXF 0.9326
48 264 0.9324
49 AG2 0.9324
50 8SZ 0.9321
51 49F 0.9320
52 THE 0.9320
53 URQ 0.9318
54 1KA 0.9317
55 5XA 0.9315
56 VKC 0.9314
57 268 0.9314
58 OAA 0.9312
59 UGC 0.9306
60 COI 0.9305
61 CEE 0.9305
62 TLA 0.9303
63 16D 0.9303
64 SGL 0.9302
65 FP1 0.9301
66 SHO 0.9294
67 CUW 0.9292
68 9YL 0.9289
69 OCT 0.9289
70 BNF 0.9289
71 NYL 0.9288
72 PG0 0.9287
73 YRL 0.9285
74 PRA 0.9284
75 BHH 0.9281
76 DGN 0.9279
77 SKG 0.9272
78 TZE 0.9272
79 FAN 0.9271
80 TAR 0.9268
81 2FT 0.9267
82 SD4 0.9264
83 98J 0.9263
84 I38 0.9260
85 GUA 0.9258
86 ITN 0.9253
87 3OL 0.9252
88 3OM 0.9252
89 717 0.9249
90 ZBT 0.9245
91 4JM 0.9245
92 HSM 0.9241
93 ZGL 0.9237
94 GOJ 0.9235
95 0VT 0.9231
96 PEA 0.9228
97 PG3 0.9228
98 O45 0.9222
99 2EH 0.9221
100 DIR 0.9219
101 SRT 0.9215
102 8GL 0.9215
103 HGA 0.9215
104 HE4 0.9215
105 JZ7 0.9213
106 40E 0.9209
107 Z82 0.9209
108 261 0.9205
109 GLY ALA 0.9197
110 PNZ 0.9195
111 CRN 0.9193
112 7OD 0.9190
113 I1E 0.9188
114 MSL 0.9187
115 9YT 0.9186
116 AEF 0.9184
117 DYA 0.9184
118 2RH 0.9184
119 NMH 0.9184
120 GLY GLY 0.9183
121 NTU 0.9182
122 DE5 0.9181
123 4SD 0.9176
124 AHB 0.9173
125 HY1 0.9171
126 DAL DAL 0.9170
127 HC4 0.9170
128 NIZ 0.9170
129 PAC 0.9169
130 1SP 0.9166
131 BSX 0.9165
132 ISZ 0.9162
133 JYD 0.9161
134 JFJ 0.9157
135 PHB 0.9154
136 AJ3 0.9153
137 MLE 0.9152
138 VAL 0.9150
139 FBM 0.9150
140 51F 0.9149
141 GJZ 0.9147
142 FQI 0.9146
143 BHL 0.9144
144 271 0.9143
145 HZP 0.9139
146 NPO 0.9137
147 SEP 0.9135
148 1DU 0.9134
149 SYM 0.9134
150 M3P 0.9134
151 TZL 0.9131
152 NF3 0.9130
153 LER 0.9128
154 2BG 0.9127
155 A8C 0.9126
156 LEA 0.9124
157 2AS 0.9123
158 XYL 0.9122
159 FEH 0.9121
160 MXN 0.9121
161 5XC 0.9115
162 PAB 0.9115
163 LDP 0.9113
164 RBL 0.9112
165 S8V 0.9111
166 HYA 0.9110
167 4FA 0.9108
168 JZ4 0.9108
169 4MA 0.9108
170 2LP 0.9107
171 AMH 0.9107
172 RBJ 0.9106
173 URP 0.9105
174 UY7 0.9103
175 MHN 0.9102
176 LNO 0.9101
177 PEP 0.9098
178 YIV 0.9097
179 IXW 0.9097
180 R67 0.9096
181 FOC 0.9094
182 TEO 0.9091
183 3PG 0.9088
184 M4T 0.9088
185 PHU 0.9086
186 PBZ 0.9083
187 URO 0.9080
188 4XR 0.9080
189 ALO 0.9079
190 54D 0.9077
191 AC6 0.9076
192 3SS 0.9076
193 HPV 0.9075
194 SIN 0.9075
195 G3P 0.9075
196 9J3 0.9074
197 DPF 0.9074
198 BHO 0.9073
199 XBT 0.9073
200 RUJ 0.9071
201 Q07 0.9071
202 RB5 0.9071
203 BZ3 0.9071
204 HBA 0.9069
205 SYN 0.9068
206 ABU 0.9068
207 2PG 0.9068
208 PRY 0.9067
209 CFI 0.9065
210 1DJ 0.9064
211 XUL 0.9063
212 PEQ 0.9062
213 HSO 0.9061
214 BPW 0.9059
215 GZ3 0.9059
216 MNN 0.9058
217 QY9 0.9057
218 MZW 0.9057
219 MLZ 0.9054
220 NXA 0.9053
221 XLS 0.9051
222 MRY 0.9050
223 5OB 0.9050
224 KDG 0.9049
225 OPE 0.9048
226 KMH 0.9047
227 SSB 0.9046
228 AMC 0.9046
229 FUM 0.9045
230 OSE 0.9044
231 DHB 0.9042
232 R2B 0.9042
233 PZI 0.9041
234 3LR 0.9040
235 HL4 0.9039
236 TPA 0.9038
237 XM0 0.9038
238 DGJ 0.9037
239 7BC 0.9036
240 BEZ 0.9036
241 HDH 0.9034
242 DAS 0.9032
243 BEN 0.9032
244 NSD 0.9031
245 6JN 0.9030
246 0V5 0.9028
247 H95 0.9028
248 OKG 0.9025
249 SPV 0.9024
250 OEG 0.9023
251 OK7 0.9022
252 KOJ 0.9021
253 5FX 0.9020
254 THR 0.9020
255 9X6 0.9019
256 4MV 0.9017
257 WTZ 0.9016
258 ALA ALA 0.9016
259 AE3 0.9016
260 O8Y 0.9013
261 7UC 0.9013
262 MEQ 0.9011
263 PBN 0.9010
264 7A8 0.9010
265 259 0.9010
266 AKB 0.9007
267 LDU 0.9007
268 XRG 0.9006
269 DZA 0.9006
270 FK8 0.9005
271 HX3 0.9005
272 T9G 0.9002
273 QDK 0.9002
274 HP6 0.9000
275 DQY 0.9000
276 PO6 0.8998
277 K6V 0.8997
278 4NM 0.8997
279 IFL 0.8996
280 NOJ 0.8996
281 HE2 0.8995
282 E5X 0.8995
283 13P 0.8992
284 URS 0.8989
285 PBC 0.8988
286 BPN 0.8986
287 AHR 0.8986
288 ROR 0.8986
289 NMG 0.8985
290 FBJ 0.8985
291 1Y6 0.8984
292 PGA 0.8984
293 A20 0.8984
294 TYL 0.8983
295 PPR 0.8982
296 I4B 0.8981
297 IHG 0.8980
298 MAE 0.8979
299 DMJ 0.8979
300 3MV 0.8979
301 QFH 0.8978
302 HBD 0.8978
303 ANN 0.8977
304 4HP 0.8976
305 DTU 0.8976
306 SR1 0.8976
307 650 0.8975
308 J0Z 0.8975
309 YPN 0.8974
310 DMV 0.8974
311 NCA 0.8974
312 SHA 0.8973
313 14J 0.8972
314 I2M 0.8970
315 ABN 0.8969
316 DCL 0.8969
317 1AB 0.8968
318 F9P 0.8967
319 MUC 0.8967
320 3H2 0.8967
321 OOG 0.8966
322 MNM 0.8965
323 2A9 0.8965
324 23B 0.8964
325 4VP 0.8964
326 J9T 0.8963
327 1SH 0.8961
328 3HP 0.8960
329 RNT 0.8959
330 PYJ 0.8959
331 7N0 0.8958
332 1LN 0.8956
333 IOM 0.8955
334 TCA 0.8955
335 IMR 0.8955
336 263 0.8953
337 3HG 0.8953
338 NIO 0.8953
339 XIZ 0.8952
340 DE2 0.8949
341 SER 0.8949
342 5XB 0.8948
343 R1X 0.8947
344 FBA 0.8947
345 BAM 0.8947
346 NBZ 0.8946
347 173 0.8946
348 CIZ 0.8946
349 BR9 0.8946
350 PYF 0.8946
351 AHN 0.8943
352 9CL 0.8943
353 ZZ3 0.8940
354 CXP 0.8940
355 TIH 0.8940
356 JB8 0.8936
357 UNU 0.8936
358 FW5 0.8935
359 KIV 0.8935
360 PZM 0.8934
361 H8N 0.8933
362 SSN 0.8933
363 1PT 0.8932
364 EDG 0.8930
365 CMS 0.8929
366 NTN 0.8928
367 6PC 0.8927
368 PBA 0.8926
369 MR1 0.8925
370 LNR 0.8924
371 4JL 0.8923
372 DHS 0.8922
373 TMH 0.8922
374 7WG 0.8921
375 42J 0.8920
376 HX2 0.8920
377 OEM 0.8918
378 OTR 0.8918
379 4JJ 0.8917
380 0L1 0.8917
381 Q9Z 0.8917
382 BP9 0.8916
383 MWJ 0.8915
384 JND 0.8915
385 2PC 0.8913
386 JDN 0.8913
387 PCA 0.8913
388 1CO 0.8913
389 2DR 0.8911
390 OCA 0.8910
391 23W 0.8908
392 YCP 0.8908
393 SHF 0.8907
394 9TY 0.8906
395 EHM 0.8906
396 NK2 0.8905
397 8EW 0.8904
398 RJY 0.8903
399 HIO 0.8903
400 174 0.8903
401 6NT 0.8902
402 826 0.8901
403 XIY 0.8899
404 RSO 0.8898
405 8WT 0.8898
406 GZL 0.8896
407 DTL 0.8895
408 HG3 0.8894
409 1M2 0.8893
410 IZC 0.8892
411 278 0.8890
412 C2B 0.8890
413 GP9 0.8889
414 JZ2 0.8889
415 G4D 0.8889
416 HY3 0.8888
417 HDA 0.8888
418 RAT 0.8888
419 F9Y 0.8887
420 5JC 0.8886
421 Y8I 0.8886
422 VGL 0.8885
423 B40 0.8884
424 TEG 0.8879
425 PGH 0.8879
426 TP5 0.8879
427 AEG 0.8877
428 MZG 0.8877
429 3SL 0.8875
430 27Y 0.8875
431 HBX 0.8875
432 ABI 0.8875
433 KTA 0.8875
434 PZA 0.8874
435 NOY 0.8874
436 RIB 0.8874
437 IF7 0.8873
438 DXX 0.8872
439 IQ0 0.8872
440 DHY 0.8871
441 269 0.8871
442 0HN 0.8871
443 HCI 0.8871
444 SS2 0.8870
445 LTL 0.8869
446 INO 0.8869
447 SMB 0.8868
448 EV0 0.8868
449 XSP 0.8868
450 APY 0.8867
451 2HO 0.8867
452 CCU 0.8866
453 MZT 0.8865
454 PAF 0.8863
455 BUB 0.8863
456 1SA 0.8861
457 B2J 0.8861
458 4NC 0.8860
459 4P5 0.8860
460 DPJ 0.8858
461 449 0.8858
462 2KT 0.8856
463 8EZ 0.8856
464 P72 0.8856
465 93K 0.8855
466 AC5 0.8854
467 PHE 0.8854
468 PSJ 0.8853
469 NBE 0.8853
470 CHB 0.8852
471 M6W 0.8851
472 HYP 0.8849
473 3A9 0.8849
474 PKU 0.8849
475 M58 0.8849
476 4M4 0.8848
477 EUG 0.8848
478 CHH 0.8848
479 MEV 0.8848
480 MLA 0.8846
481 G3H 0.8845
482 9TW 0.8845
483 QMP 0.8844
484 1F1 0.8844
485 JLZ 0.8843
486 B24 0.8842
487 5HY 0.8840
488 OHG 0.8840
489 COM 0.8839
490 P9P 0.8838
491 J9N 0.8838
492 QSC 0.8837
493 3QM 0.8836
494 BNS 0.8836
495 ODV 0.8836
496 SVJ 0.8834
497 JZ5 0.8834
498 FHB 0.8834
499 4ZA 0.8833
500 Z6J 0.8832
501 OC9 0.8829
502 FCN 0.8828
503 069 0.8828
504 192 0.8828
505 FPI 0.8827
506 LFC 0.8826
507 F06 0.8825
508 2ZM 0.8825
509 2AL 0.8824
510 F4E 0.8824
511 5AC 0.8822
512 4WL 0.8820
513 NNO 0.8820
514 XYD 0.8820
515 MRZ 0.8819
516 HIS 0.8819
517 SYG 0.8819
518 LLQ 0.8819
519 HHI 0.8818
520 X1S 0.8818
521 282 0.8818
522 3NY 0.8817
523 4A3 0.8816
524 AT3 0.8815
525 3OC 0.8814
526 IP8 0.8813
527 PY7 0.8813
528 2XX 0.8813
529 PLU 0.8812
530 K34 0.8812
531 32O 0.8812
532 4LR 0.8812
533 53C 0.8811
534 K6H 0.8810
535 FUD 0.8809
536 ETM 0.8809
537 8X3 0.8808
538 MLI 0.8808
539 HUI 0.8808
540 SPD 0.8808
541 GIF 0.8806
542 MCT 0.8806
543 KPL 0.8805
544 1MR 0.8804
545 4CL 0.8803
546 9SE 0.8800
547 AX3 0.8800
548 PRO 0.8800
549 2HU 0.8799
550 SMN 0.8799
551 IFM 0.8798
552 RNS 0.8797
553 SNE 0.8796
554 129 0.8796
555 V55 0.8796
556 3HM 0.8795
557 ICN 0.8795
558 NM2 0.8795
559 NM3 0.8795
560 M45 0.8794
561 OHP 0.8794
562 IHB 0.8794
563 34V 0.8794
564 PAH 0.8793
565 QBM 0.8793
566 4CS 0.8793
567 SC2 0.8792
568 BUA 0.8792
569 HGQ 0.8792
570 TYE 0.8791
571 6NI 0.8791
572 3YP 0.8790
573 1GP 0.8789
574 3PP 0.8789
575 DHI 0.8789
576 JZ3 0.8789
577 PYD 0.8788
578 5NI 0.8788
579 RMN 0.8785
580 L99 0.8784
581 DSN 0.8784
582 8ZE 0.8784
583 DHK 0.8783
584 92K 0.8781
585 ICF 0.8781
586 3S5 0.8781
587 UYA 0.8780
588 EFS 0.8780
589 P2D 0.8780
590 BML 0.8780
591 9SB 0.8779
592 GPJ 0.8778
593 GPF 0.8778
594 SOL 0.8777
595 XX2 0.8776
596 ORO 0.8775
597 QSB 0.8772
598 2HC 0.8772
599 CCD 0.8772
600 AOS 0.8771
601 SHI 0.8771
602 FRU 0.8771
603 FPK 0.8770
604 SS1 0.8767
605 R9S 0.8766
606 CYX 0.8766
607 45L 0.8765
608 XBZ 0.8765
609 P7Y 0.8764
610 4CH 0.8763
611 DEE 0.8763
612 ACH 0.8763
613 EOU 0.8763
614 0HO 0.8762
615 PRS 0.8761
616 S76 0.8761
617 MT2 0.8761
618 OXZ 0.8759
619 41K 0.8758
620 AAE 0.8757
621 ASC 0.8756
622 3MB 0.8755
623 60P 0.8754
624 AS3 0.8754
625 SOR 0.8754
626 RTK 0.8754
627 GLO 0.8753
628 PRI 0.8753
629 GAB 0.8753
630 OVM 0.8752
631 TFB 0.8752
632 B85 0.8750
633 RIP 0.8750
634 TIU 0.8749
635 VPR 0.8748
636 S2P 0.8748
637 7MU 0.8748
638 GRO 0.8746
639 2D8 0.8746
640 H76 0.8745
641 3XX 0.8745
642 3AL 0.8744
643 GG6 0.8743
644 ABV 0.8743
645 MYJ 0.8742
646 AC0 0.8740
647 OVP 0.8740
648 AGK 0.8739
649 2FG 0.8738
650 3ZQ 0.8738
651 GLL 0.8738
652 N2I 0.8737
653 8NY 0.8737
654 GLA 0.8736
655 FSG 0.8736
656 1P8 0.8736
657 TPO 0.8735
658 URF 0.8734
659 A5E 0.8733
660 64K 0.8733
661 TAG 0.8731
662 TNE 0.8731
663 3PY 0.8731
664 HT4 0.8729
665 PDC 0.8729
666 ES2 0.8727
667 AMS 0.8727
668 H7Y 0.8726
669 1P3 0.8725
670 2AC 0.8725
671 97T 0.8724
672 ICP 0.8724
673 LYL 0.8724
674 RUU 0.8724
675 LUQ 0.8723
676 3AB 0.8723
677 PUT 0.8722
678 11S 0.8721
679 3V4 0.8721
680 KG7 0.8719
681 C2A 0.8719
682 PD2 0.8718
683 PCT 0.8718
684 DFU 0.8718
685 GAL 0.8716
686 IVA 0.8715
687 SAN 0.8715
688 BVC 0.8715
689 HVQ 0.8715
690 2A7 0.8714
691 O7U 0.8714
692 RSF 0.8714
693 ARB 0.8713
694 JZ1 0.8712
695 BXO 0.8712
696 ES9 0.8712
697 3C4 0.8711
698 TYR 0.8711
699 FLA 0.8710
700 3HB 0.8710
701 9RW 0.8709
702 0OC 0.8709
703 IT2 0.8709
704 D1X 0.8708
705 PSE 0.8705
706 OVV 0.8705
707 TB6 0.8703
708 149 0.8702
709 BAE 0.8702
710 DMG 0.8701
711 NK1 0.8699
712 273 0.8697
713 P81 0.8694
714 SKM 0.8694
715 2RA 0.8693
716 4J8 0.8693
717 IOL 0.8691
718 QOS 0.8690
719 IDH 0.8690
720 8OZ 0.8690
721 E4P 0.8690
722 MAN 0.8688
723 R8A 0.8687
724 4DX 0.8687
725 2MH 0.8686
726 CCE 0.8686
727 R2P 0.8685
728 T6C 0.8684
729 ES6 0.8683
730 23A 0.8682
731 2BX 0.8682
732 VNJ 0.8681
733 0R0 0.8681
734 DYT 0.8681
735 DTT 0.8680
736 TH7 0.8680
737 WBU 0.8679
738 RM1 0.8678
739 OW4 0.8675
740 ESP 0.8674
741 AEH 0.8673
742 POA 0.8673
743 1A7 0.8669
744 GDE 0.8669
745 4XV 0.8668
746 SYC 0.8668
747 24B 0.8667
748 KP6 0.8666
749 2FY 0.8666
750 MTL 0.8664
751 3BZ 0.8663
752 4HO 0.8661
753 FOM 0.8660
754 AX7 0.8660
755 TDR 0.8660
756 BZ2 0.8658
757 TBP 0.8657
758 1MC 0.8656
759 ZZT 0.8655
760 HPP 0.8655
761 IP0 0.8652
762 AZF 0.8651
763 S24 0.8651
764 5MH 0.8650
765 MZ0 0.8650
766 X6X 0.8648
767 2YU 0.8648
768 0MK 0.8646
769 AAS 0.8645
770 FUB 0.8643
771 XCZ 0.8643
772 CP 0.8642
773 DGY 0.8640
774 PMF 0.8640
775 J9Q 0.8640
776 G2H 0.8638
777 VNL 0.8637
778 MTG 0.8637
779 HDL 0.8637
780 DFB 0.8637
781 HPS 0.8635
782 4TB 0.8635
783 GYE 0.8634
784 7VD 0.8634
785 NVI 0.8634
786 3NT 0.8633
787 FPY 0.8633
788 MPD 0.8632
789 286 0.8631
790 PTO 0.8630
791 HMH 0.8630
792 IPU 0.8629
793 DBH 0.8626
794 6FZ 0.8625
795 MAK 0.8624
796 ARG 0.8623
797 152 0.8622
798 MAH 0.8622
799 ESX 0.8621
800 PPY 0.8620
801 P92 0.8620
802 NSP 0.8620
803 I3A 0.8620
804 N9J 0.8619
805 4SX 0.8619
806 PRZ 0.8619
807 NK 0.8619
808 R9M 0.8616
809 FBS 0.8615
810 A3B 0.8615
811 APG 0.8615
812 4XS 0.8614
813 43M 0.8613
814 TAU 0.8613
815 MSR 0.8612
816 P80 0.8611
817 2MP 0.8610
818 5MB 0.8608
819 HIU 0.8600
820 DOR 0.8599
821 PIY 0.8599
822 03W 0.8599
823 8GC 0.8596
824 EKZ 0.8596
825 4HS 0.8596
826 FUC 0.8596
827 FUF 0.8594
828 GAF 0.8594
829 ABE 0.8592
830 G8M 0.8592
831 A09 0.8591
832 CHT 0.8590
833 34A 0.8590
834 4JU 0.8588
835 284 0.8586
836 4JN 0.8585
837 JAW 0.8584
838 ZXD 0.8581
839 GLC 0.8581
840 8WO 0.8581
841 TM7 0.8580
842 MLM 0.8580
843 5NU 0.8579
844 2EZ 0.8575
845 2D0 0.8575
846 911 0.8575
847 BGC 0.8573
848 B3U 0.8571
849 4ZE 0.8570
850 OXC 0.8569
851 TSS 0.8568
852 SAT 0.8568
853 MPV 0.8566
854 TFU 0.8565
855 XQG 0.8565
856 HMU 0.8564
857 FBW 0.8560
858 PEZ 0.8559
859 PBE 0.8558
860 7MH 0.8555
861 61M 0.8550
862 54G 0.8544
863 CWM 0.8544
864 PC 0.8541
865 S0H 0.8533
866 ILO 0.8531
867 MS9 0.8527
868 XYS 0.8513
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2V7T; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2v7t.bio1) has 86 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2V7T; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2v7t.bio1) has 86 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2V7T; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2v7t.bio1) has 86 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2V7T; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2v7t.bio1) has 86 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 2V7T; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 2v7t.bio1) has 86 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 2V7T; Ligand: SAH; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 2v7t.bio1) has 86 residues
No: Leader PDB Ligand Sequence Similarity
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