Receptor
PDB id Resolution Class Description Source Keywords
2C5L 1.9 Å EC: 3.6.5.2 STRUCTURE OF PLC EPSILON RAS ASSOCIATION DOMAIN WITH HRAS HOMO SAPIENS SIGNALING PROTEIN/COMPLEX RAS UBIQUITIN SUPERFOLD ONCOGENE GTP-BINDING NUCLEOTIDE- BINDING SIGNALING PROTEIN DISEASE MUTATION LIPOPROTEIN PALMITATE PRENYLATION PROTO-ONCOGENE
Ref.: STRUCTURAL AND MECHANISTIC INSIGHTS INTO RAS ASSOCIATION DOMAINS OF PHOSPHOLIPASE C EPSILON MOL.CELL V. 21 495 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:1169;
A:1170;
B:1169;
C:3240;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
GTP A:1167;
B:1167;
Valid;
Valid;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG A:1168;
B:1168;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2C5L 1.9 Å EC: 3.6.5.2 STRUCTURE OF PLC EPSILON RAS ASSOCIATION DOMAIN WITH HRAS HOMO SAPIENS SIGNALING PROTEIN/COMPLEX RAS UBIQUITIN SUPERFOLD ONCOGENE GTP-BINDING NUCLEOTIDE- BINDING SIGNALING PROTEIN DISEASE MUTATION LIPOPROTEIN PALMITATE PRENYLATION PROTO-ONCOGENE
Ref.: STRUCTURAL AND MECHANISTIC INSIGHTS INTO RAS ASSOCIATION DOMAINS OF PHOSPHOLIPASE C EPSILON MOL.CELL V. 21 495 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 2C5L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 14 families.
1 2C5L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 10 families.
1 2C5L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2C5L; Ligand: GTP; Similar sites found: 415
This union binding pocket(no: 1) in the query (biounit: 2c5l.bio2) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1GXU 2HP 0.0003165 0.49656 None
2 2YY8 MTA 0.009536 0.41862 None
3 1PTR PRB 0.04416 0.4001 None
4 2VOH CIT 0.01989 0.40082 1.91083
5 3N5C GDP 0.000000002689 0.74785 2.5641
6 4KAX GTP 0.00000000003543 0.68088 2.5641
7 4KJU 1RH 0.01012 0.43325 2.5641
8 3IIJ ADP 0.00002578 0.41436 2.5641
9 1R18 SAH 0.006408 0.4024 2.89017
10 1TE2 PGA 0.03703 0.40165 3.4188
11 1TQ4 GDP 0.0000000585 0.6277 3.46821
12 3EZ2 ADP 0.000153 0.51853 3.46821
13 2ZTS ADP 0.0009837 0.44809 3.46821
14 5L3W GDP 0.00001811 0.44193 4.04624
15 3BER AMP 0.01256 0.41679 4.04624
16 4E3Q PMP 0.02171 0.40489 4.04624
17 1BO4 COA 0.02652 0.40053 4.16667
18 2X77 GDP 0.0000000005397 0.76984 4.2735
19 1NJF AGS 0.0001445 0.438 4.2735
20 1NJF ADP 0.0001622 0.42446 4.2735
21 2Q37 3AL 0.03299 0.40468 4.2735
22 1ZVX FIN 0.007623 0.40136 4.29448
23 1UPT GTP 0.00000000001385 0.69348 4.62428
24 1G6O ADP 0.0001506 0.50012 4.62428
25 1IWE IMP 0.0007391 0.48564 4.62428
26 3B7G ANP 0.0008428 0.46976 4.62428
27 3DC4 ADP 0.000001079 0.43672 4.62428
28 1L2T ATP 0.0008385 0.43574 4.62428
29 5FTB ANP 0.0001505 0.50014 5.12821
30 5FHD ADP ALF 0.0003712 0.46244 5.12821
31 3H86 AP5 0.001124 0.4342 5.12821
32 2J5V PCA 0.03086 0.42534 5.12821
33 1V0O INR 0.007632 0.41197 5.12821
34 1G6H ADP 0.000005506 0.6212 5.20231
35 5K5Z ANP 0.00009372 0.45673 5.20231
36 4U60 SIA GAL NGA 0.02765 0.40405 5.20231
37 3QXC ATP 0.003711 0.40339 5.20231
38 4GBM A3P 0.004455 0.40902 5.26316
39 2OBM ADP 0.0004077 0.51021 5.78035
40 2B8W ALF 5GP 0.000006622 0.50034 5.78035
41 3ZS9 ADP ALF 0.00004842 0.47786 5.78035
42 2WOJ ADP ALF 0.00007364 0.47066 5.78035
43 1W7J ADP BEF 0.00001629 0.53304 5.96026
44 2A5F GTP 0.0000000001354 0.67914 5.98291
45 1VHT BA3 0.0004952 0.47564 5.98291
46 2BEK ATP 0.0001698 0.47268 5.98291
47 1YTM ATP 0.000315 0.46554 5.98291
48 4Q1A UDP 0.00785 0.45182 5.98291
49 4Q1A 2XZ 0.00785 0.45182 5.98291
50 4GOX A3P 0.00213 0.42243 5.98291
51 5I34 GDP 0.00007659 0.41492 5.98291
52 1T8U UAP SGN IDS SGN 0.007276 0.40652 5.98291
53 5H68 AGS 0.00108 0.40243 5.98291
54 1HTW ADP 0.00005857 0.41338 6.32911
55 5KUT GDP 0.00000000112 0.55483 6.34921
56 4WZ6 ATP 0.00002109 0.57795 6.35838
57 2DPY ADP 0.0001689 0.52339 6.35838
58 4R43 GDP 0.000453 0.48851 6.35838
59 4QOS ADP 0.0007883 0.46608 6.35838
60 2NZ5 226 0.006384 0.43476 6.35838
61 3RC3 ANP 0.00843 0.42988 6.35838
62 2ZPA ADP 0.000262 0.41629 6.35838
63 1QF9 C5P 0.006742 0.40468 6.35838
64 1QF9 ALF 0.006742 0.40468 6.35838
65 1QF9 ADP 0.006742 0.40468 6.35838
66 3WYA GDP 0.0000000006933 0.77707 6.45161
67 1G8S MET 0.009969 0.43259 6.52174
68 4WOP CTP 0.0000354 0.4539 6.66667
69 3U6B GDP 0.000000000122 0.82875 6.83761
70 2BVN GNP 0.00000000001616 0.81721 6.83761
71 4G5G GDP 0.0000000005313 0.7828 6.83761
72 3U6K GDP 0.0000000008172 0.77352 6.83761
73 3NHB ADP 0.00002896 0.57029 6.83761
74 2HCJ GDP 0.0000000001161 0.55473 6.83761
75 5JBQ GDP 0.0000000004124 0.55371 6.83761
76 1D8T GDP 0.0000000004062 0.55358 6.83761
77 5BQ5 ADP BEF 0.0001064 0.50727 6.83761
78 3ZQ6 ADP ALF 0.00004201 0.48029 6.83761
79 1B0U ATP 0.001679 0.44605 6.83761
80 3IO3 ADP 0.000169 0.42576 6.83761
81 2OZE AGS 0.0002443 0.41937 6.83761
82 3H4S ADP 0.000003062 0.40345 6.83761
83 4FRZ ADP 0.000008951 0.40247 6.83761
84 5TSH ANP 0.00007076 0.40119 6.83761
85 3CNL GNP 0.000000002419 0.76277 6.93642
86 1GOJ ADP 0.0000005612 0.67223 6.93642
87 3ZFD ANP 0.0000001284 0.51008 6.93642
88 1M7G ADX 0.001136 0.42989 6.93642
89 2X7I CIT 0.007627 0.42759 6.93642
90 3BFX A3P 0.002927 0.42707 6.93642
91 1M7G ADP 0.001481 0.42231 6.93642
92 1M7G AV2 0.00001449 0.41498 6.93642
93 1TAD ALF 0.000000001926 0.65723 7.51445
94 1TAD GDP 0.000000001926 0.65723 7.51445
95 4H1V GNP 0.000004976 0.55637 7.51445
96 1LVG ADP 0.000003245 0.42148 7.51445
97 1IN4 ADP 0.0004822 0.4066 7.51445
98 2ZFI ADP 0.00001265 0.56562 7.69231
99 3T34 GDP 0.00001866 0.5084 7.69231
100 5I0H ADP BEF 0.000001109 0.50824 7.69231
101 2C9O ADP 0.00006203 0.49621 7.69231
102 4YS0 ADP 0.0009794 0.45243 7.69231
103 1S3G AP5 0.003449 0.42004 7.69231
104 2Z49 AMG 0.02115 0.41533 7.69231
105 2Z48 NGA 0.03671 0.4103 7.69231
106 1O8B ABF 0.02344 0.40712 7.69231
107 3EF0 ALF 0.03056 0.40682 7.69231
108 1CS4 GSP 0.0000000003899 0.66683 8.09249
109 3LRE ADP 0.0000007938 0.6638 8.09249
110 1AZT GSP 0.0000000002865 0.66018 8.09249
111 5IRR GSP 0.00000001423 0.64635 8.09249
112 1G7C 5GP 0.0000005228 0.63429 8.09249
113 2RCN GDP 0.00000000005277 0.57729 8.09249
114 4CVN ADP 0.00002382 0.5678 8.09249
115 4P3Y GDP 0.0000000001955 0.55034 8.09249
116 4IDN GNP 0.00004372 0.49778 8.09249
117 2BIF ANP 0.001453 0.42834 8.09249
118 2BIF SIN 0.002597 0.42834 8.09249
119 1K6M AGS 0.00207 0.42294 8.09249
120 4PU6 ASP 0.02731 0.40778 8.39695
121 5EE5 GTP 0.000000000001973 0.72406 8.54701
122 3PCR GTP 0.0000000004476 0.70142 8.54701
123 2XT3 ADP 0.000002327 0.63405 8.54701
124 5M04 GDP 0.000000001357 0.53386 8.54701
125 2GK6 ADP 0.001577 0.47273 8.54701
126 1ION ADP 0.0001299 0.41242 8.54701
127 3VMF GTP 0.00000000006835 0.69918 8.67052
128 3WXM GTP 0.00000000009858 0.69315 8.67052
129 1D2E GDP 0.00000001605 0.67846 8.67052
130 4IOK ADP 0.001907 0.4164 8.67052
131 4IOK XPO 0.001285 0.41386 8.67052
132 3COB ADP 0.000001982 0.40773 8.67052
133 2IL4 COA 0.01593 0.40068 8.73786
134 4LC1 GDP 0.00000000431 0.73769 9.24856
135 2HF9 GSP 0.00000004229 0.65018 9.24856
136 2NCD ADP 0.00001131 0.59082 9.24856
137 4PC3 GDP 0.00000003074 0.5374 9.24856
138 1W5T ANP 0.0004699 0.45799 9.24856
139 1W5T ADP 0.0008229 0.45586 9.24856
140 3R7F CP 0.01386 0.42569 9.24856
141 4WEI GLC GAL 0.01916 0.41609 9.24856
142 2GWH A3P 0.007023 0.41361 9.24856
143 2HXW FLC 0.0227 0.41202 9.24856
144 2OAT PFM 0.01382 0.40022 9.24856
145 2C78 GNP 0.00000000002579 0.76315 9.40171
146 2C77 GNP 0.00000000004932 0.66362 9.40171
147 1V8K ANP 0.0000001619 0.65955 9.40171
148 1JI0 ATP 0.00003504 0.55905 9.40171
149 3Q9L ATP 0.00002823 0.52222 9.40171
150 1G3Q ADP 0.00007656 0.52024 9.40171
151 1FP6 ADP 0.00004251 0.51999 9.40171
152 2VB6 ADP BEF 0.00006048 0.45769 9.40171
153 3FWY ADP 0.00001181 0.4572 9.40171
154 4PFO ADP 0.0001724 0.45122 9.40171
155 2OFW ADX 0.001436 0.43476 9.40171
156 4V03 ADP 0.00003632 0.42786 9.40171
157 2PEZ GGZ 0.001474 0.42672 9.40171
158 2PEZ DAT 0.001474 0.42672 9.40171
159 3FB4 AP5 0.00329 0.4209 9.40171
160 2FAH GDP 0.0002294 0.41313 9.40171
161 1X6V ADP 0.001561 0.40844 9.40171
162 4D81 ADP 0.0002106 0.4076 9.40171
163 4ME6 ADP 0.02982 0.40685 9.40171
164 3DOE GTP 0.00000000006981 0.68023 9.69697
165 1WDT GTP 0.000000004258 0.68604 9.82659
166 2CBZ ATP 0.0000007449 0.67431 9.82659
167 1D2N ANP 0.002831 0.42407 9.82659
168 4NZ6 DGL 0.03055 0.40715 9.82659
169 1F9V ADP 0.000008024 0.40381 9.82659
170 5IFS ADP 0.0002019 0.40145 9.82659
171 1F5N GNP 0.00001172 0.50218 10.2564
172 3KTA AP5 0.0004851 0.47104 10.2564
173 4A4Z ANP 0.004215 0.4404 10.2564
174 4OI4 ATP 0.001371 0.43043 10.2564
175 4MKG AP5 0.002 0.4299 10.2564
176 4MKF AP5 0.003417 0.42127 10.2564
177 1SKQ GDP 0.000000006947 0.73946 10.4046
178 3TK1 GDP 0.0000000005924 0.52571 10.4046
179 5VGR GDP 0.0004198 0.46911 10.4046
180 1OYY AGS 0.002975 0.44793 10.4046
181 1P4V GLY 0.02474 0.41065 10.4046
182 2WIC GNP 0.00000002396 0.69003 10.9827
183 4R98 GNH 0.000001187 0.46876 10.9827
184 2IYL GDP 0.000009013 0.57293 11.1111
185 2OG2 MLI 0.0001067 0.53376 11.1111
186 1KK8 BEF ADP 0.00002166 0.52743 11.1111
187 3MD0 GDP 0.000000001611 0.52723 11.1111
188 3B9Q MLI 0.0001843 0.52675 11.1111
189 1B7T ADP 0.00007133 0.51549 11.1111
190 1QAN SAH 0.0008247 0.43965 11.1111
191 3VM7 GLC 0.01078 0.4383 11.1111
192 2RGX AP5 0.003704 0.42083 11.1111
193 2QZ4 ADP 0.00007765 0.41401 11.1111
194 3UIE ANP 0.00008929 0.41314 11.1111
195 1OS1 PYR 0.002788 0.41277 11.1111
196 1OS1 ATP 0.002887 0.41073 11.1111
197 5MVR ADP 0.00005552 0.40591 11.1111
198 5HR5 ADP 0.0003813 0.4052 11.1111
199 1ZUI SKM 0.0003219 0.45776 11.3095
200 2WJG GDP 0.00000001598 0.70945 11.5607
201 5N69 ADP 0.0000298 0.43488 11.5607
202 1XEX ATP 0.003916 0.40531 11.5607
203 2W58 ADP 0.0000004125 0.69176 11.9658
204 1KSH GDP 0.00000000001627 0.68 11.9658
205 5HCN GCP 0.0000000005583 0.56708 11.9658
206 1G41 ADP 0.00009746 0.50907 11.9658
207 3A4M ADP 0.00001451 0.40681 11.9658
208 5H56 ADP 0.0041 0.40604 11.9658
209 5H56 TYD 0.0041 0.40604 11.9658
210 2VVG ADP 0.0000006825 0.40582 11.9658
211 2CE7 ADP 0.000192 0.40116 11.9658
212 2WJH GDP 0.00000001581 0.53311 12.0482
213 2WJH FLC 0.000002008 0.47171 12.0482
214 4NON GDP 0.0000002592 0.55757 12.1387
215 3FKQ ATP 0.00003517 0.5179 12.1387
216 2XTZ GSP 0.0000000001113 0.69231 12.7168
217 4ZKD GDP 0.0000000001832 0.69203 12.7168
218 1JJ7 ADP 0.000004232 0.62937 12.7168
219 4YDS ATP 0.0000302 0.56242 12.7168
220 1SVK ALF GDP 0.000000000791 0.67538 12.8205
221 2OM2 GDP 0.000001194 0.57077 12.8205
222 1Y3A GDP 0.0000002864 0.54818 12.8205
223 3EC1 GDP 0.000000008373 0.53209 12.8205
224 4XGU ADP 0.0004038 0.46987 12.8205
225 5J1J ANP 0.00005866 0.45853 12.8205
226 2UVO NDG 0.02314 0.42325 12.8205
227 3QKT ANP 0.001164 0.41395 12.8205
228 1F2U ATP 0.002319 0.41147 12.8205
229 5GJC ATP 0.00004539 0.40672 12.8205
230 1BH2 GSP 0.0000000009603 0.6693 13.0159
231 1FQK ALF 0.00000005076 0.72454 13.2308
232 1FQJ ALF 0.00000004423 0.71882 13.2308
233 1FQJ GDP 0.00000004511 0.61772 13.2308
234 1FQK GDP 0.0000001141 0.60088 13.2308
235 1Y63 ADP 0.00003702 0.54248 13.2948
236 2C04 GCP 0.0001851 0.48522 13.2948
237 4MDB RLT 0.01284 0.43355 13.2948
238 2IXE ATP 0.0004896 0.41868 13.2948
239 2QEN ADP 0.0001997 0.41641 13.2948
240 2ODE ALF GDP 0.0000000006772 0.67535 13.6752
241 1SQ5 ADP 0.0001142 0.51183 13.6752
242 3FVQ ATP 0.0001719 0.47697 13.6752
243 1OFH ADP 0.0000886 0.41313 13.6752
244 1R6B ADP 0.00008807 0.41027 13.6752
245 1R4A GNP 0.00000000004261 0.69711 13.7255
246 3PQC GDP 0.00000002203 0.68167 13.8728
247 5L3R GCP 0.000002602 0.53855 13.8728
248 4LYA ATP 0.00007219 0.52148 13.8728
249 2PL3 ADP 0.0004857 0.49302 13.8728
250 5J1S ATP 0.001469 0.41101 13.8728
251 2GDJ ANP 0.0001159 0.51789 14.4509
252 1IHU AF3 0.0001226 0.47869 14.4509
253 1IHU ADP 0.0001566 0.46981 14.4509
254 3FYH ADP 0.003568 0.40994 14.4509
255 1JWY GDP 0.000001616 0.58574 14.5299
256 1JWY ADP 0.0000212 0.54726 14.5299
257 3E70 GDP 0.00001111 0.44256 14.5299
258 4TMZ GSP 0.00000000000438 0.78537 15.0289
259 4NCN GTP 0.000000000003006 0.72724 15.0289
260 3CX8 GSP 0.0000000003972 0.65515 15.0289
261 3AB3 GDP 0.00000002564 0.57094 15.0289
262 1ZCB GDP 0.0000001989 0.56612 15.0289
263 1MKY GDP 0.0000000001311 0.56528 15.0289
264 3ZIA ADP 0.0001681 0.41229 15.0289
265 4UOX PUT 0.008971 0.41229 15.0289
266 4UOX PLP 0.01396 0.41057 15.0289
267 3ZIA ATP 0.00008098 0.40854 15.0289
268 3BFV ADP 0.0000502 0.53592 15.3846
269 5G41 AP5 0.004776 0.4191 15.3846
270 2AWN ADP 0.0000006988 0.68319 15.6069
271 2CHG ANP 0.0002399 0.48012 15.6069
272 3RLF ANP 0.0003065 0.45762 15.6069
273 4IEE AGS 0.0003399 0.5009 16.2393
274 5XDR ADP 0.0009989 0.46619 16.2393
275 2FNA ADP 0.0002674 0.46427 16.2393
276 4RLQ 3SK 0.02365 0.41108 16.2393
277 2JLR ANP 0.0002252 0.40749 16.2393
278 1PUJ GNP 0.0000000008911 0.58268 16.763
279 5X40 ACP 0.0009271 0.41264 16.763
280 5GOE GDP 0.00000002179 0.68189 17.094
281 4AG5 ADP 0.00002089 0.57701 17.094
282 3B5J 12D 0.00006216 0.54605 17.094
283 1QF5 RPL 0.006053 0.4463 17.094
284 3QF7 ANP 0.001537 0.42459 17.341
285 1GOT GDP 0.0000002476 0.54259 17.8082
286 5CK5 GDP 0.000000000344 0.54771 17.9191
287 4ZG4 VO4 ADP 0.000002477 0.50938 17.9487
288 4XTR ATP 0.0001197 0.44784 17.9487
289 4XVU ATP 0.0001278 0.44682 17.9487
290 4XTR ADP 0.0001132 0.43222 17.9487
291 1QHH ATP 0.01045 0.41668 17.9487
292 1GP2 GDP 0.0000007006 0.56795 18.3099
293 4P4T GDP 0.000004161 0.5534 18.4971
294 4BQS ADP 0.0001514 0.51213 18.4971
295 4BQS K2Q 0.006349 0.40462 18.4971
296 4RD0 GDP 0.000000000006232 0.70487 18.8034
297 4WZA ADP 0.00005947 0.5132 18.8034
298 4WZA ACP 0.00005957 0.51317 18.8034
299 1FNN ADP 0.0002513 0.47439 18.8034
300 1Z6T ADP 0.0003286 0.47393 18.8034
301 1P9B GDP 0.0003865 0.47073 18.8034
302 1P9B HDA 0.01478 0.42367 18.8034
303 1LOB MMA 0.04138 0.40018 18.8034
304 4PPF FLC 0.000009999 0.60051 19.0751
305 5L3S GNP 0.000008263 0.49623 19.0751
306 2ZR9 DTP 0.0003242 0.49572 19.0751
307 5L3V GDP 0.000005678 0.45686 19.0751
308 2W83 GTP 0.00000000009321 0.72989 19.4805
309 4HI0 GDP 0.0000003613 0.59334 19.6532
310 1KK1 GNP 0.000000001693 0.53041 19.6581
311 5IRN ADP 0.0001593 0.41218 19.6581
312 4LPS GDP 0.0000000626 0.66982 20.2312
313 4J0Q GDP 0.0000000005934 0.79381 20.5128
314 2XTN GTP 0.0000008499 0.56445 20.5128
315 1H65 GDP 0.00001032 0.48114 20.8092
316 4E03 ADP 0.00003447 0.42617 21.3675
317 3WY9 GDP 0.0000000002486 0.81303 21.875
318 1CR1 TTP 0.0006535 0.40859 21.9653
319 4OHY ANP 0.00007281 0.47925 22.2222
320 2Q2Y ADP 0.00103 0.44191 22.2222
321 2Q2Y MKR 0.001156 0.43866 22.2222
322 4RZ3 ADP 0.0001424 0.42547 23.0769
323 3W5J GDP 0.0000008284 0.65261 24.2775
324 2V7Q ADP 0.00002735 0.54901 24.2775
325 2V7Q ATP 0.00009891 0.50877 24.2775
326 2CK3 ANP 0.0002304 0.47606 24.2775
327 2CK3 ADP 0.0003861 0.45343 24.2775
328 1W0J ADP BEF 0.0002578 0.41736 24.2775
329 1W0J ADP 0.0001497 0.41495 24.2775
330 2FH5 GTP 0.000000000003759 0.80989 24.8555
331 3VX3 ADP 0.0002481 0.47464 24.8555
332 3DZD ADP 0.0006278 0.46585 24.8555
333 3KJI ADP 0.000112 0.42227 26.5896
334 4B47 GDP 0.0000000001015 0.83282 27.1676
335 4HSE ADP 0.00004173 0.53301 28.2051
336 1YRB GDP 0.0000000002497 0.76218 28.3237
337 1G7S GDP 0.000000003764 0.72897 28.9017
338 1S9D GDP 0.00000001018 0.70805 31.2139
339 1RE0 GDP 0.0000000009745 0.53507 31.2139
340 4DCT GDP 0.0000000002516 0.7859 31.7919
341 3AQ4 GDP 0.0000000049 0.72342 31.7919
342 1WF3 GNP 0.0000000009533 0.66373 31.7919
343 1NRJ GTP 0.0000000004479 0.63273 32.2785
344 1ZD9 GDP 0.000000000006581 0.81073 32.3699
345 4YLG GDP 0.00000000494 0.5703 32.3699
346 1YZG GDP 0.000000004745 0.53989 32.3699
347 1ZJ6 G3D 0.000000003982 0.72779 32.948
348 2QN6 GDP 0.0000000002554 0.81243 33.3333
349 1J2J GTP 0.00000000002563 0.75331 33.7349
350 2J59 GTP 0.00000000006442 0.73659 33.7349
351 1O3Y GTP 0.0000000001065 0.72747 33.7349
352 1SVI GDP 0.0000000003382 0.54345 35.2601
353 5KSZ GCP 0.00000006948 0.51918 36.4162
354 1DAR GDP 0.00000002755 0.51353 36.4162
355 5KSP GDP 0.00000005611 0.50915 36.4162
356 2QTV GNP 0.000000001233 0.64334 38.1503
357 2ZEJ GDP 0.000001459 0.53794 38.1503
358 4GOJ GNP 0.00000000001426 0.69391 38.7283
359 4ZI2 GNP 0.0000000000156 0.69244 38.7283
360 1FZQ GDP 0.0000000008852 0.5484 38.7283
361 5KDO GDP 0.0000006626 0.58189 39.1892
362 1M2O GNP 0.00000000124 0.65109 39.3064
363 1F6B GDP 0.00000003044 0.51874 39.8844
364 5DI3 GNP 0.0000000000979 0.73847 40.4624
365 2GJ8 ALF GDP 0.0000000005658 0.67268 40.4624
366 4V0K GDP 0.0000005456 0.56636 40.8284
367 5FG3 GDP 0.00000000007229 0.56149 42.1965
368 1MR3 G3D 0.000000003357 0.54538 42.1965
369 3A1S GDP 0.00000007777 0.66526 43.3526
370 1M7B GTP 0.0000000000004227 0.85114 43.9306
371 1GWN GTP 0.0000000000005255 0.73178 43.9306
372 3REF GDP 0.0000000003253 0.71625 46.2428
373 3GJX GTP 0.00000000000001354 0.85518 46.8208
374 3RAB GNP 0.00000000000001821 0.83742 46.8208
375 3GJ4 GDP 0.0000000001033 0.8181 46.8208
376 3GJ7 GDP 0.0000000001355 0.81225 46.8208
377 3GJ8 GDP 0.0000000001088 0.80354 46.8208
378 3GJ5 GDP 0.0000000001306 0.5851 46.8208
379 5UWP GNP 0.000000000000004441 0.87855 47.3988
380 5UWQ GNP 0.000000000000003553 0.87807 47.3988
381 5UWI GNP 0.000000000000003775 0.87689 47.3988
382 5UWJ GNP 0.000000000000003886 0.87652 47.3988
383 4HAT GNP 0.000000000000005107 0.87589 47.3988
384 5UWR GNP 0.000000000000004108 0.87578 47.3988
385 5DHF GNP 0.000000000000004108 0.87567 47.3988
386 5DI9 GNP 0.000000000000005329 0.87526 47.3988
387 5UWO GNP 0.000000000000004441 0.87419 47.3988
388 5UWW GNP 0.000000000000004663 0.87343 47.3988
389 5UWT GNP 0.000000000000004774 0.87328 47.3988
390 5UWS GNP 0.000000000000005995 0.87326 47.3988
391 5UWU GNP 0.000000000000004885 0.8729 47.3988
392 5UWH GNP 0.00000000000000544 0.87093 47.3988
393 1IBR GNP 0.000000000000006106 0.86897 47.3988
394 3GJ0 GDP 0.0000000001243 0.81411 47.3988
395 1NF3 GNP 0.0000000000002383 0.79422 47.3988
396 1WA5 GTP 0.00000000000001388 0.78529 47.3988
397 5BXQ GDP 0.0000000000876 0.58886 47.3988
398 3CH5 GDP 0.0000000002109 0.57972 47.3988
399 3GJ3 GDP 0.0000000001823 0.56636 47.3988
400 3M1I GTP 0.000000000000007661 0.86487 47.9769
401 3WYF GTP 0.00000000000001621 0.85604 47.9769
402 3WYG GTP 0.00000000000004119 0.81814 47.9769
403 2WMO GTP 0.000000000005979 0.85051 48.5549
404 1GRN GDP 0.00000000002372 0.79747 48.5549
405 4DID GDP 0.0000000005743 0.76853 48.5549
406 1GRN AF3 0.0000001103 0.68967 48.5549
407 2NGR GDP 0.000000000004839 0.62254 48.5549
408 4ITR GDP 0.00000001399 0.56444 48.5549
409 2NGR AF3 0.000000008897 0.49379 48.5549
410 1D5C GDP 0.00000000002066 0.64688 48.7654
411 1A4R GDP 0.00000000002743 0.65817 49.1329
412 1A4R GNH 0.00000000002266 0.64981 49.1329
413 1Z0J GTP 0.00000000000001699 0.85137 49.4118
414 3E5H GNP 0.000000000001103 0.76924 49.711
415 4YC7 GNP 0.0000000000001645 0.76121 49.711
Pocket No.: 2; Query (leader) PDB : 2C5L; Ligand: GTP; Similar sites found: 9
This union binding pocket(no: 2) in the query (biounit: 2c5l.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1YXM ADE 0.04125 0.40688 5.12821
2 4U60 SIA 0.01171 0.42228 5.20231
3 4U60 SIA GAL BGC NGA GAL 0.03036 0.40133 5.20231
4 3MBI HSX 0.03047 0.40124 6.83761
5 1D8C SOR 0.04256 0.40215 11.9658
6 5KGS 6SR 0.008941 0.40754 12.7168
7 1YBH P22 0.02479 0.40199 15.6069
8 1LES GLC FRU 0.02884 0.41185 19.6581
9 4TTQ ATP 0.0001203 0.40001 20.5128
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