Receptor
PDB id Resolution Class Description Source Keywords
2CJW 2.1 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE SMALL GTPASE GEM (GEMDNDCAM) IN COMPLEX TO MG.GDP HOMO SAPIENS G-PROTEIN NUCLEOTIDE-BINDING GTP-BINDING SMALL GTPASE CONFORMATIONAL CHANGE CYSTEINE-MODIFIED G-PROTEIN HYDROLASE
Ref.: BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF THE GEM GTPASE. J.BIOL.CHEM. V. 282 1905 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:999;
B:999;
Valid;
Valid;
none;
none;
Kd = 2.5 uM
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:1000;
B:1000;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2CJW 2.1 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE SMALL GTPASE GEM (GEMDNDCAM) IN COMPLEX TO MG.GDP HOMO SAPIENS G-PROTEIN NUCLEOTIDE-BINDING GTP-BINDING SMALL GTPASE CONFORMATIONAL CHANGE CYSTEINE-MODIFIED G-PROTEIN HYDROLASE
Ref.: BIOCHEMICAL AND STRUCTURAL CHARACTERIZATION OF THE GEM GTPASE. J.BIOL.CHEM. V. 282 1905 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 2CJW Kd = 2.5 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 2CJW Kd = 2.5 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 1GUA Kd = 40 nM GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
2 3KUC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1C1Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
4 2CJW Kd = 2.5 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 4KVG - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
6 2A9K - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
7 1WQ1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 3KUD - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 5XCO - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
10 1NVU - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
11 4URZ Kd = 3 mM VJP C11 H14 N2 O3 S c1cc(ccc1N....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2CJW; Ligand: GDP; Similar sites found: 541
This union binding pocket(no: 1) in the query (biounit: 2cjw.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3H86 AP5 0.00005536 0.54585 None
2 3DKP ADP 0.00008455 0.49793 None
3 3B7G ANP 0.0001765 0.47167 None
4 2B8T THM 0.004138 0.43416 None
5 2B4D COA 0.01069 0.41228 None
6 1GHE ACO 0.01958 0.40425 None
7 4KVX ACO 0.02426 0.40247 None
8 1U0J ADP 0.000229 0.46836 1.04167
9 1OE0 TTP 0.001819 0.45854 1.04167
10 2I4I AMP 0.008853 0.4125 1.04167
11 4PPF FLC 0.0000006137 0.64448 1.5625
12 2Q2Y MKR 0.00006874 0.5468 1.5625
13 2Q2Y ADP 0.00007297 0.5468 1.5625
14 4KBF AMP 0.001172 0.43807 1.5625
15 1Q20 A3P 0.01125 0.42698 1.5625
16 1Q20 PLO 0.01125 0.42698 1.5625
17 1S7N COA 0.008558 0.41698 1.64835
18 4NCN GTP 0.0000000001237 0.80423 2.08333
19 3DEF GDP 0.00000002268 0.6767 2.08333
20 4TMZ GSP 0.0000000001754 0.60087 2.08333
21 1Y63 ADP 0.000001073 0.58633 2.17391
22 2RCN GDP 0.0000000000009065 0.86938 2.60417
23 1D2N ANP 0.001303 0.45666 2.60417
24 5MEX PAP 0.00761 0.41761 2.60417
25 5MEX SZZ 0.03074 0.40875 2.60417
26 1KNR FAD 0.03708 0.40818 2.60417
27 3L9W GSH 0.0301 0.40159 2.60417
28 1BG2 ADP 0.0000001695 0.53184 3.125
29 1UJ2 ADP 0.00008562 0.52442 3.125
30 1UJ2 C5P 0.0001178 0.51754 3.125
31 2PL3 ADP 0.0001267 0.49647 3.125
32 2GDJ ANP 0.0001128 0.49208 3.125
33 5FTB ANP 0.00008226 0.47377 3.125
34 5FHD ADP ALF 0.00003679 0.44306 3.125
35 4M0R 644 0.0258 0.41825 3.125
36 3FYH ADP 0.00006803 0.41002 3.125
37 1Q0S SAH 0.01925 0.40609 3.125
38 3BFX A3P 0.001431 0.40195 3.125
39 3BOS CDP 0.00005871 0.50531 3.30579
40 1B0U ATP 0.00004176 0.5213 3.43511
41 5H56 ADP 0.000007982 0.58156 3.64583
42 5H56 TYD 0.000007982 0.58156 3.64583
43 1F9V ADP 0.00000049 0.55409 3.64583
44 3TMK T5A 0.00005228 0.53879 3.64583
45 4PX9 ADP 0.00001344 0.52349 3.64583
46 1SQ5 ADP 0.00001404 0.51903 3.64583
47 4FCW ADP 0.00004347 0.51459 3.64583
48 4IHQ ADP 0.00002655 0.51083 3.64583
49 2WHX ADP 0.000009554 0.50157 3.64583
50 4ZNL BEF ADP 0.00008508 0.5009 3.64583
51 3T34 GDP 0.000001485 0.48834 3.64583
52 3TBK ANP 0.00009206 0.47656 3.64583
53 2FNA ADP 0.000003027 0.47145 3.64583
54 1NST A3P 0.001645 0.44759 3.64583
55 2GK6 ADP 0.0006177 0.44121 3.64583
56 4A4Z ANP 0.001658 0.43767 3.64583
57 3VM7 GLC 0.01041 0.41197 3.64583
58 1XX6 ADP 0.0006849 0.45558 3.66492
59 4HUT ATP 0.0104 0.42498 3.66492
60 3R96 AMP 0.02465 0.41375 3.7234
61 3R96 ACO 0.02465 0.41375 3.7234
62 1QF9 ADP 0.0002252 0.51759 4.12371
63 1QF9 ALF 0.0002252 0.51759 4.12371
64 1QF9 C5P 0.0002252 0.51759 4.12371
65 2NCD ADP 0.0000006347 0.62566 4.16667
66 5J1J ANP 0.000002046 0.59776 4.16667
67 2ZPA ADP 0.0000238 0.53835 4.16667
68 4XGU ADP 0.00002233 0.53704 4.16667
69 5K5Z ANP 0.00004699 0.5333 4.16667
70 1RRC ADP 0.0000009732 0.52146 4.16667
71 2PZE ATP 0.000001015 0.52091 4.16667
72 2FAH GDP 0.00005309 0.51633 4.16667
73 4WZ6 ATP 0.000005123 0.5127 4.16667
74 4IEE AGS 0.0002179 0.48521 4.16667
75 4IOK ADP 0.0006863 0.48123 4.16667
76 4IOK XPO 0.0006258 0.47799 4.16667
77 5TIV A3P 0.009213 0.44091 4.16667
78 5EP2 AZU 0.009256 0.41533 4.16667
79 4ITM ATP 0.01669 0.40919 4.16667
80 1VJ7 GPX 0.01333 0.40191 4.16667
81 2ZTS ADP 0.00004521 0.44899 4.38247
82 3TK1 GDP 0.0000000000201 0.76202 4.6875
83 4ZKD GDP 0.00000000153 0.76001 4.6875
84 2W58 ADP 0.0000001563 0.6777 4.6875
85 2HF9 GSP 0.000000004428 0.61922 4.6875
86 4H1V GNP 0.0000001408 0.56949 4.6875
87 3UIE ANP 0.000005484 0.56013 4.6875
88 5I34 GDP 0.000005437 0.55699 4.6875
89 5I0H ADP BEF 0.00001884 0.5458 4.6875
90 5TSH ANP 0.000008758 0.54382 4.6875
91 1CR1 TTP 0.00002336 0.54128 4.6875
92 4PFO ADP 0.00003685 0.54058 4.6875
93 1T5C ADP 0.0000003215 0.52184 4.6875
94 2ZR9 DTP 0.00002665 0.5213 4.6875
95 4R43 GDP 0.00003115 0.51814 4.6875
96 5TSH ADP 0.000008495 0.50564 4.6875
97 2GMV UN8 0.0008256 0.47722 4.6875
98 1NHX PEP 0.002261 0.47281 4.6875
99 2GMV PEP 0.001193 0.47232 4.6875
100 1NHX FTB 0.003056 0.46697 4.6875
101 5WRJ A3P 0.001209 0.46393 4.6875
102 5WRI A3P 0.001241 0.45966 4.6875
103 2C9O ADP 0.00001614 0.45931 4.6875
104 1YTM ATP 0.00002939 0.45498 4.6875
105 5VGR GDP 0.0000859 0.45157 4.6875
106 2J5V PCA 0.03435 0.40528 4.6875
107 5J1S ATP 0.0001212 0.51307 4.87805
108 1XEX ATP 0.00007066 0.40336 4.94506
109 1NRJ GTP 0.000000001361 0.74641 5.06329
110 5FG3 GDP 0.00000000000834 0.80086 5.20833
111 1KK1 GNP 0.0000000001307 0.74889 5.20833
112 1GOJ ADP 0.0000000344 0.70781 5.20833
113 3FWY ADP 0.0000003184 0.62544 5.20833
114 4AG5 ADP 0.000001433 0.60841 5.20833
115 3B9Q MLI 0.000004922 0.58682 5.20833
116 2WOJ ADP ALF 0.000007061 0.57819 5.20833
117 4D81 ADP 0.000007405 0.55705 5.20833
118 3FB4 AP5 0.00009551 0.54076 5.20833
119 4ZG4 VO4 ADP 0.00003149 0.53966 5.20833
120 4MKG AP5 0.000121 0.53543 5.20833
121 5X40 ACP 0.0000441 0.5325 5.20833
122 4KFU ACP 0.000002246 0.52873 5.20833
123 2RGX AP5 0.0001832 0.52858 5.20833
124 5G41 AP5 0.0002235 0.52752 5.20833
125 3EZ2 ADP 0.00002931 0.5269 5.20833
126 2BIF SIN 0.0002147 0.52618 5.20833
127 2BIF ANP 0.0001259 0.52618 5.20833
128 5LTJ ADP 0.00002466 0.52616 5.20833
129 5HR5 ADP 0.00004464 0.52262 5.20833
130 1W5T ANP 0.00007533 0.51664 5.20833
131 2XAU ADP 0.00004728 0.51589 5.20833
132 5XDR ADP 0.00006017 0.50796 5.20833
133 2JLR ANP 0.0000996 0.50333 5.20833
134 4JLV ADP 0.0000417 0.50235 5.20833
135 1W5T ADP 0.0001701 0.49479 5.20833
136 4LJ9 ACP 0.0001017 0.49419 5.20833
137 1W7J ADP BEF 0.00002239 0.47156 5.20833
138 1FNN ADP 0.0000204 0.46445 5.20833
139 4QRH 0O2 0.0012 0.45839 5.20833
140 3HU3 AGS 0.04147 0.44384 5.20833
141 4R2I ANP 0.0009066 0.43949 5.20833
142 1OYY AGS 0.00166 0.43764 5.20833
143 3ZS9 ADP ALF 0.000006383 0.43612 5.20833
144 2OG2 MLI 0.000002719 0.43346 5.20833
145 2Z5F A3P 0.004058 0.43273 5.20833
146 1G3M A3P 0.01417 0.42726 5.20833
147 1G3M PCQ 0.01417 0.42726 5.20833
148 3EVF GTA 0.01969 0.42175 5.20833
149 3IUY AMP 0.004399 0.41789 5.20833
150 5HR5 FLC 0.01969 0.41339 5.20833
151 1J99 AND 0.02178 0.41229 5.20833
152 3MD0 GDP 0.0000000000255 0.77901 5.72917
153 1SKQ GDP 0.0000000003623 0.72914 5.72917
154 1G7C 5GP 0.00000006625 0.64269 5.72917
155 5L3W GDP 0.0000002226 0.62593 5.72917
156 2QZ4 ADP 0.000005548 0.55989 5.72917
157 1S3G AP5 0.00008479 0.54343 5.72917
158 3DC4 ADP 0.000002499 0.53899 5.72917
159 2C04 GCP 0.00000236 0.52063 5.72917
160 3DZD ADP 0.00007918 0.50807 5.72917
161 2IS6 ADP 0.00005281 0.50745 5.72917
162 1G6O ADP 0.00002771 0.49139 5.72917
163 2B8W ALF 5GP 0.0003414 0.49094 5.72917
164 3Q9L ATP 0.00002584 0.47258 5.72917
165 5MZN ADP 0.0006183 0.44287 5.72917
166 1T8U A3P 0.0091 0.41569 5.72917
167 1T8U UAP SGN IDS SGN 0.02608 0.41442 5.72917
168 2RDT FMN 0.01574 0.41188 5.72917
169 2RDT 2RD 0.02107 0.41188 5.72917
170 2XWL CTP 0.01114 0.4077 5.72917
171 5HCN GCP 0.00000000005555 0.79134 6.25
172 1AZT GSP 0.0000000007961 0.77981 6.25
173 1M7G ADX 0.00001092 0.57656 6.25
174 1M7G AV2 0.000000867 0.57656 6.25
175 5IRN ADP 0.000003391 0.5732 6.25
176 4NON GDP 0.00000000008011 0.56452 6.25
177 3COB ADP 0.00000009828 0.56157 6.25
178 1M7G ADP 0.00001878 0.56103 6.25
179 4LYA ATP 0.00000524 0.55774 6.25
180 1WDT GTP 0.0000001933 0.54274 6.25
181 4P32 ADP 0.00003596 0.53457 6.25
182 2CHG ANP 0.00002904 0.53157 6.25
183 2XTN GTP 0.00000005157 0.5298 6.25
184 4U00 ADP 0.000000249 0.52362 6.25
185 4OI4 ATP 0.0003394 0.48912 6.25
186 2QG6 NMN 0.0006969 0.48089 6.25
187 4TMK T5A 0.003971 0.45002 6.25
188 2BEK ATP 0.00008462 0.42841 6.25
189 1AQU A3P 0.004518 0.42654 6.25
190 5K04 COA 0.007459 0.42336 6.25
191 3WQT ANP 0.01166 0.41217 6.25
192 1HTW ADP 0.000002478 0.57301 6.32911
193 3KTA AP5 0.00003635 0.47457 6.35838
194 4QM7 GTP 0.0000163 0.53124 6.43275
195 5NUL FMN 0.00565 0.42188 6.52174
196 1YZG GDP 0.000000000009566 0.82721 6.70391
197 3WYA GDP 0.000000000002919 0.84571 6.77083
198 3WY9 GDP 0.00000000001096 0.83449 6.77083
199 4B47 GDP 0.000000000002247 0.82566 6.77083
200 1PUJ GNP 0.0000000001345 0.7827 6.77083
201 5CK5 GDP 0.00000000002644 0.77939 6.77083
202 2C77 GNP 0.0000000009012 0.75508 6.77083
203 2XTZ GSP 0.000000002682 0.745 6.77083
204 1G7S GDP 0.0000000001062 0.74488 6.77083
205 1DAR GDP 0.0000000006155 0.73739 6.77083
206 5GOE GDP 0.0000000002279 0.70731 6.77083
207 1G6H ADP 0.00000012 0.68448 6.77083
208 2C78 GNP 0.0000000003031 0.61077 6.77083
209 1LVG ADP 0.0000001959 0.58748 6.77083
210 1JI0 ATP 0.000002624 0.58651 6.77083
211 2QEN ADP 0.000005771 0.56517 6.77083
212 2VVG ADP 0.00000003982 0.55429 6.77083
213 1W0J ADP 0.000009153 0.55267 6.77083
214 2CE7 ADP 0.00001305 0.54232 6.77083
215 4MKF AP5 0.0001117 0.53851 6.77083
216 4HSE ADP 0.000006976 0.53201 6.77083
217 1R6B ADP 0.00001926 0.53119 6.77083
218 1OXV ANP 0.000009161 0.52903 6.77083
219 1W0J ADP BEF 0.0000684 0.51627 6.77083
220 5L3R GCP 0.00000007001 0.51311 6.77083
221 4QOS ADP 0.00005114 0.48157 6.77083
222 1ZK7 FAD 0.04904 0.43015 6.77083
223 5GLN XYS 0.01107 0.41652 6.77083
224 1VKJ A3P 0.009314 0.4152 6.77083
225 2O0J ADP 0.004426 0.40826 6.77083
226 1TB3 FMN 0.03146 0.4018 6.77083
227 5MVR ADP 0.000006212 0.55077 6.79012
228 4CVN ADP 0.0000007774 0.61249 6.80628
229 4BQS ADP 0.000003704 0.56124 6.81818
230 4BQS K2Q 0.00003448 0.55787 6.81818
231 3IO3 ADP 0.000003832 0.57656 6.89655
232 5EE5 GTP 0.000000000006414 0.86321 7.01754
233 1ZUI SKM 0.00004278 0.55308 7.14286
234 3IIJ ADP 0.000001393 0.58103 7.22222
235 3CNL GNP 0.0000000002367 0.73575 7.29167
236 1JWY GDP 0.00000003648 0.66689 7.29167
237 3VX3 ADP 0.000005893 0.56756 7.29167
238 2OFW ADX 0.0000287 0.56638 7.29167
239 1UKZ ADP 0.00008242 0.53551 7.29167
240 1JWY ADP 0.00002259 0.52794 7.29167
241 4YMU ATP 0.00001056 0.52653 7.29167
242 1NY5 ADP 0.00006208 0.51576 7.29167
243 2F3R G5P 0.004732 0.44488 7.29167
244 3V2U ATP 0.006027 0.42619 7.29167
245 5MZI FAD 0.03794 0.41945 7.29167
246 5MZI FYK 0.03894 0.41945 7.29167
247 2VB6 ADP BEF 0.00002885 0.54152 7.38255
248 1KO8 6PG 0.00003363 0.53112 7.42857
249 5H67 ATP 0.001728 0.43948 7.44681
250 1GXU 2HP 0.00007017 0.5049 7.69231
251 1MR3 G3D 0.000000000001722 0.86218 7.73481
252 2IL4 COA 0.002193 0.40495 7.76699
253 2FH5 GTP 0.00000000002561 0.82999 7.8125
254 1ZCB GDP 0.000000001664 0.75525 7.8125
255 1IHU AF3 0.0000005258 0.62393 7.8125
256 1IHU ADP 0.0000005975 0.62393 7.8125
257 4WZA ACP 0.000006282 0.62378 7.8125
258 4WZA ADP 0.000006282 0.62378 7.8125
259 1FQJ GDP 0.0000000007998 0.58789 7.8125
260 4V03 ADP 0.000001661 0.58466 7.8125
261 1FQK GDP 0.000000003117 0.57229 7.8125
262 1IN4 ADP 0.000008927 0.55887 7.8125
263 1FP6 ADP 0.0000008143 0.54392 7.8125
264 5IRR GSP 0.00000003591 0.5433 7.8125
265 1V8K ANP 0.00001192 0.53759 7.8125
266 5IFS ADP 0.00001741 0.5364 7.8125
267 1YQT ADP 0.000001527 0.53217 7.8125
268 1OS1 PYR 0.0001017 0.52606 7.8125
269 1OS1 ATP 0.00009393 0.52606 7.8125
270 5M7P ADP 0.00008418 0.51193 7.8125
271 4IDN GNP 0.0001253 0.50816 7.8125
272 2FSH ANP 0.0003923 0.4584 7.8125
273 2PEZ DAT 0.00001534 0.57088 7.82123
274 2PEZ GGZ 0.00001534 0.57088 7.82123
275 1ZJ6 G3D 0.00000000001034 0.78997 8.02139
276 1TAD ALF 0.000000001267 0.76972 8.33333
277 1TAD GDP 0.000000001267 0.76972 8.33333
278 4LC1 GDP 0.0000000003628 0.74809 8.33333
279 3E70 GDP 0.00000009262 0.64004 8.33333
280 4RZ3 ADP 0.000003155 0.57774 8.33333
281 1NJF ADP 0.000004044 0.57544 8.33333
282 1NJF AGS 0.000007467 0.56781 8.33333
283 1XKV ATP 0.00001894 0.53467 8.33333
284 3FKQ ATP 0.000004123 0.50522 8.33333
285 2ZPT A3P 0.03532 0.41786 8.33333
286 3RC3 ANP 0.003768 0.41418 8.33333
287 2X7I CIT 0.006849 0.4089 8.33333
288 1F6B GDP 0.0000000001989 0.76532 8.85417
289 1IWE IMP 0.0001419 0.57299 8.85417
290 2ZFI ADP 0.000006045 0.55132 8.85417
291 5N69 ADP 0.00001888 0.53771 8.85417
292 4WOP CTP 0.0002269 0.49344 8.85417
293 1Z6T ADP 0.00001843 0.4755 8.85417
294 4W6Z 8ID 0.0466 0.42375 8.85417
295 4GOX A3P 0.00008603 0.41992 8.85417
296 1L2T ATP 0.0000931 0.40575 8.85417
297 1BO4 COA 0.004314 0.41828 8.92857
298 4M7V RAR 0.04905 0.4042 9.14286
299 4M7V NAP 0.0324 0.4023 9.14286
300 1SVK ALF GDP 0.00000000109 0.77566 9.375
301 1BH2 GSP 0.000000002853 0.75207 9.375
302 1Y3A GDP 0.000000001883 0.74635 9.375
303 2CBZ ATP 0.000000137 0.67666 9.375
304 2IYL GDP 0.00000006394 0.64341 9.375
305 2OM2 GDP 0.00000000185 0.60634 9.375
306 1G41 ADP 0.000009832 0.54814 9.375
307 1OFH ADP 0.00002286 0.53081 9.375
308 2OZE AGS 0.00003998 0.5275 9.375
309 5GJC ATP 0.00005663 0.50604 9.375
310 2VF7 ADP 0.00007668 0.50302 9.375
311 3FVQ ATP 0.00004781 0.43961 9.375
312 3MGB PAP 0.007049 0.42108 9.375
313 3BER AMP 0.004179 0.41893 9.375
314 3LRE ADP 0.00000009846 0.68406 9.89583
315 5L3S GNP 0.0000001021 0.66425 9.89583
316 5L3V GDP 0.00000003775 0.66237 9.89583
317 3ZQ6 ADP ALF 0.000001038 0.61951 9.89583
318 2Y65 ADP 0.0000005172 0.53458 9.89583
319 1X6V ADP 0.00002088 0.40884 9.89583
320 3U6B GDP 0.00000000000756 0.8422 10.4167
321 1D8T GDP 0.00000000001987 0.80688 10.4167
322 5JBQ GDP 0.00000000002653 0.80104 10.4167
323 4P3Y GDP 0.000000000008269 0.80086 10.4167
324 4G5G GDP 0.00000000002999 0.79855 10.4167
325 3U6K GDP 0.00000000005284 0.78709 10.4167
326 4PC3 GDP 0.0000000003525 0.76279 10.4167
327 2BVN GNP 0.00000000006555 0.7055 10.4167
328 4HI0 GDP 0.0000000003991 0.62403 10.4167
329 2XT3 ADP 0.0000001173 0.55848 10.4167
330 5LB3 ADP 0.00005977 0.49604 10.4167
331 1R0X ATP 0.0001271 0.48009 10.4167
332 2ZE7 DST 0.003925 0.44194 10.4167
333 2ZE7 AMP 0.003648 0.44194 10.4167
334 2D2F ADP 0.00003266 0.43923 10.4167
335 5ULP KB1 0.01489 0.41165 10.4167
336 4KVA GTP 0.0000003829 0.40939 10.4167
337 4J0Q GDP 0.00000000002152 0.82046 10.9375
338 1D2E GDP 0.0000000002189 0.77264 10.9375
339 2AWN ADP 0.00000001641 0.74482 10.9375
340 1GOT GDP 0.000000002906 0.73386 10.9375
341 4LPS GDP 0.0000000008009 0.70678 10.9375
342 1TQ4 GDP 0.00000000004213 0.65467 10.9375
343 1GP2 GDP 0.000000002494 0.57559 10.9375
344 3A4M ADP 0.0000005252 0.57028 10.9375
345 4E03 ADP 0.00001019 0.54419 10.9375
346 3RLF ANP 0.0000481 0.53065 10.9375
347 1CS4 GSP 0.00000001222 0.50975 10.9375
348 1QHG ATP 0.003261 0.43118 10.9375
349 3VMF GTP 0.000000001065 0.76483 11.4583
350 1SVI GDP 0.00000000007723 0.7589 11.4583
351 3WXM GTP 0.000000001888 0.75254 11.4583
352 4YDS ATP 0.000005758 0.56972 11.4583
353 2DPY ADP 0.00002419 0.53905 11.4583
354 2KIN ADP 0.0000001614 0.53199 11.4583
355 2HCJ GDP 0.000000000007567 0.80258 11.6418
356 4KAX GTP 0.0000000001108 0.80295 11.8343
357 3BFV ADP 0.000002419 0.56987 11.9792
358 3QKT ANP 0.00004206 0.53567 11.9792
359 2W83 GTP 0.0000000001572 0.60505 12.1212
360 1P9B GDP 0.00001632 0.54355 12.5
361 1T3D CYS 0.00609 0.42145 12.5
362 3ZIA ADP 0.00001856 0.53806 12.6984
363 3ZIA ATP 0.00001852 0.532 12.6984
364 1B7T ADP 0.00003288 0.49017 12.8205
365 2V7Q ATP 0.000005596 0.55971 13.0137
366 2V7Q ADP 0.00004857 0.50915 13.0137
367 2CK3 ANP 0.00008362 0.44477 13.0137
368 2CK3 ADP 0.00007945 0.42022 13.0137
369 5M04 GDP 0.00000000000786 0.80266 13.0208
370 1M2O GNP 0.00000000192 0.75217 13.1579
371 1O3Y GTP 0.0000000001205 0.80479 13.253
372 1J2J GTP 0.0000000001003 0.60791 13.253
373 2J59 GTP 0.000000000194 0.60175 13.253
374 1QF5 GDP 0.00005349 0.56464 13.5417
375 1QF5 RPL 0.001763 0.51445 13.5417
376 3P4X ADP 0.000005116 0.54235 14.0436
377 3EC1 GDP 0.0000000001363 0.77304 14.0625
378 1H65 GDP 0.00000007662 0.66466 14.0625
379 2GJ8 ALF GDP 0.0000000004375 0.55361 14.5349
380 3KJI ADP 0.000001729 0.58712 14.5833
381 3B5J 12D 0.000009203 0.5597 14.5833
382 2QTV GNP 0.0000000008719 0.76598 14.9701
383 1UPT GTP 0.00000000007175 0.81214 15
384 1KK8 BEF ADP 0.00002159 0.47262 15.1079
385 4V0K GDP 0.00000000003069 0.6112 15.3846
386 1F2U ATP 0.00009214 0.52284 15.4362
387 1NN5 ANP 0.00003344 0.55206 15.625
388 3ZFD ANP 0.0000319 0.52397 15.625
389 1ION ADP 0.000009504 0.54883 16.1458
390 4YS0 ADP 0.0003344 0.4312 16.6667
391 3AQ4 GDP 0.000000000002988 0.81322 16.8478
392 4XTR ADP 0.00000369 0.57735 17.1875
393 4XTR ATP 0.000005345 0.57735 17.1875
394 4XVU ATP 0.000006275 0.57394 17.1875
395 1JJV ATP 0.00001201 0.50414 17.7083
396 1S9D GDP 0.000000000003833 0.80871 18.2927
397 1RE0 GDP 0.000000000008164 0.8013 18.2927
398 4RD0 GDP 0.00000000007809 0.81035 18.75
399 2QN6 GDP 0.00000000001969 0.78498 18.75
400 3EWA ANP 0.00002702 0.52102 18.75
401 4Q1A 2XZ 0.0004379 0.56169 19.2708
402 4Q1A UDP 0.0004379 0.56169 19.2708
403 2D7D ADP 0.0002518 0.47583 20
404 2X77 GDP 0.00000000003127 0.76828 20.1058
405 2OBM ADP 0.00008785 0.52084 20.3125
406 1JJ7 ADP 0.00000008857 0.69237 20.8333
407 3PCR GTP 0.0000000002566 0.59862 20.9877
408 2IXE ATP 0.00004264 0.53096 21.875
409 4TTQ ATP 0.00004104 0.51256 22.3958
410 1K6M AGS 0.00006881 0.52304 23.4375
411 1R4A GNP 0.000000000002068 0.89507 23.5294
412 4YLG GDP 0.000000000001902 0.87562 24.8555
413 5DI3 GNP 0.00000000003806 0.63714 25.5208
414 4M9Q GNP 0.00000000006872 0.62944 25.5208
415 4BAS GNP 0.0000000006873 0.76435 26.0417
416 3A1S GDP 0.000000003103 0.68393 27.5194
417 3DOE GTP 0.00000000005579 0.82115 27.6042
418 1ZD9 GDP 0.00000000004732 0.66895 27.6596
419 5KUT GDP 0.00000000006679 0.78758 28.0423
420 1WF3 GNP 0.0000000006433 0.77868 28.125
421 1KSH GDP 0.00000000001551 0.84054 28.4946
422 2ZEJ GDP 0.0000000001883 0.80515 29.3478
423 3T1O GDP 0.0000000007061 0.74408 30.2083
424 3T12 GDP ALF 0.0000000008566 0.5991 30.2083
425 1FZQ GDP 0.00000000001438 0.81343 30.9392
426 2WIC GNP 0.0000000007445 0.7089 31.25
427 5KSZ GCP 0.000000256 0.62306 31.25
428 5KSP GDP 0.00000005866 0.64936 31.5789
429 1VHT BA3 0.0001805 0.48838 31.7708
430 4R98 GNH 0.000000005249 0.69401 32.8125
431 2A5F GTP 0.00000000005575 0.82471 33.1429
432 1G3Q ADP 0.000003622 0.54627 33.3333
433 4ZI2 GNP 0.00000000004859 0.82039 33.6842
434 4GOJ GNP 0.00000000003652 0.82642 33.8624
435 3N5C GDP 0.00000000003737 0.7941 34.5679
436 2G77 GDP 0.000000000005569 0.72128 35.4167
437 2G77 AF3 0.01112 0.4127 35.4167
438 1Z06 GNP 0.00000000001473 0.85314 35.9788
439 3E5H GNP 0.0000000002823 0.79331 37.0787
440 1GWN GTP 0.000000005287 0.71786 38.0208
441 3REF GDP 0.000000002521 0.57987 38.5417
442 4DID GDP 0.0000000005724 0.74377 39.0625
443 2WMO GTP 0.0000000007682 0.74235 39.4737
444 1NF3 GNP 0.000000009212 0.71853 39.5833
445 1M7B GTP 0.000000001942 0.59919 39.6739
446 1A4R GDP 0.0000000009026 0.75134 39.7906
447 2NGR GDP 0.0000000005629 0.74411 39.7906
448 4ITR GDP 0.00000000142 0.74186 39.7906
449 1A4R GNH 0.00000000144 0.73772 39.7906
450 1GRN GDP 0.000000001525 0.73653 39.7906
451 2EW1 GNP 0.000000000008389 0.86143 40.1042
452 5JCP GDP ALF 0.000000002277 0.62923 40.1042
453 2W2X GSP 0.000000001661 0.74221 41.0811
454 3W5J GDP 0.00000007665 0.57231 41.1458
455 1KMQ GNP 0.000000004288 0.72886 41.3043
456 1Z0F GDP 0.0000000000006797 0.88114 41.3408
457 5IRC GDP 0.00000001228 0.68542 41.3979
458 4D0N GDP 0.0000000001964 0.76052 41.6216
459 5HPY GDP 0.000000001378 0.73865 41.6216
460 3LXR GDP 0.000000000431 0.69527 41.6216
461 2WKQ GTP 0.000000002179 0.57004 41.6667
462 4YC7 GNP 0.000000002868 0.73414 41.9889
463 2WJG GDP 0.00000000005692 0.78558 42.0213
464 4XOI GTP 0.000000007068 0.72129 42.2222
465 1CXZ GSP 0.000000005236 0.72141 42.3077
466 1OW3 GDP 0.000000001947 0.73146 42.7083
467 2WJH GDP 0.0000000008833 0.73492 42.7711
468 2WJH FLC 0.00000007249 0.64897 42.7711
469 4XSH GSP 0.000000001883 0.73595 43.0168
470 1VG8 GNP 0.000000000002112 0.90192 43.2292
471 1VG0 GDP 0.0000000000006009 0.89456 43.2292
472 3BC1 GNP 0.000000000004088 0.88417 43.2292
473 3GJX GTP 0.0000000001198 0.81491 43.2292
474 4D0G GTP 0.000000000004184 0.87225 43.4286
475 1TX4 ALF GDP 0.000000007964 0.55615 43.5028
476 5BXQ GDP 0.000000000003787 0.84611 43.75
477 5UWP GNP 0.00000000003279 0.84602 43.75
478 5UWW GNP 0.00000000003018 0.84461 43.75
479 5DIF GNP 0.00000000003093 0.84408 43.75
480 5UWU GNP 0.00000000003178 0.8435 43.75
481 5UWI GNP 0.00000000003229 0.84315 43.75
482 5UWS GNP 0.00000000003789 0.8429 43.75
483 4HAT GNP 0.00000000003805 0.84281 43.75
484 5UWR GNP 0.00000000003395 0.84207 43.75
485 5DHF GNP 0.00000000003464 0.84164 43.75
486 3WYF GTP 0.00000000004179 0.84078 43.75
487 5UWT GNP 0.00000000003683 0.84032 43.75
488 3M1I GTP 0.00000000003955 0.83878 43.75
489 5DI9 GNP 0.00000000004758 0.83797 43.75
490 3GJ0 GDP 0.000000000006155 0.83061 43.75
491 3CH5 GDP 0.000000000009137 0.82814 43.75
492 3GJ3 GDP 0.000000000009126 0.82264 43.75
493 1DS6 GDP 0.00000000009092 0.7761 43.75
494 5UWQ GNP 0.0000000000273 0.58374 43.75
495 5UWJ GNP 0.0000000000283 0.58339 43.75
496 5UWO GNP 0.00000000003114 0.58233 43.75
497 5UWH GNP 0.00000000003284 0.5818 43.75
498 1IBR GNP 0.00000000005901 0.57656 43.75
499 3SBD GNP 0.000000004498 0.73391 43.8503
500 3GJ5 GDP 0.000000000008455 0.82973 44.2708
501 3GJ7 GDP 0.000000000008383 0.82436 44.2708
502 3GJ4 GDP 0.000000000008837 0.82329 44.2708
503 3GJ8 GDP 0.000000000006989 0.79676 44.2708
504 1RYH GNP 0.0000000001972 0.77028 44.2708
505 1OIX GDP 0.000000000006567 0.874 44.5026
506 1MH1 GNP 0.000000001587 0.75922 44.6237
507 1E96 GTP 0.000000003901 0.73697 44.7917
508 3TKL GTP 0.000000000004758 0.63074 44.7917
509 1VG1 GDP 0.0000000000001898 0.90715 44.8649
510 1VG9 GDP 0.0000000000003529 0.8945 44.8649
511 1OIV GDP 0.00000000000609 0.87562 45.0262
512 2A5J GDP 0.0000000000008238 0.80503 45.0262
513 1Z2A GDP 0.0000000000546 0.61784 45.2381
514 5SZH GNP 0.000000000003385 0.89176 45.3125
515 2BCG GDP 0.000000000003 0.70957 45.3125
516 1Z0K GTP 0.00000000001525 0.63312 45.3488
517 1YZN GNP 0.00000000000788 0.59689 45.4054
518 1G4U GDP 0.000000001866 0.61553 45.6522
519 3CPJ GDP 0.000000000003865 0.85608 45.8333
520 1I4D GDP 0.000000000114 0.75078 45.8333
521 1Z0J GTP 0.00000000001279 0.59435 45.8824
522 3RAB GNP 0.00000000001349 0.85855 46.1538
523 3WYG GTP 0.00000000006971 0.8297 46.1538
524 2BME GNP 0.00000000002348 0.84667 46.2366
525 2F9L GDP 0.00000000001207 0.63662 46.3542
526 1HE1 GDP 0.000000001312 0.60396 46.5909
527 1HE1 AF3 0.0116 0.41182 46.5909
528 2FJU GSP 0.000000001262 0.74799 46.6292
529 1YVD GNP 0.00000000001036 0.60999 47.3373
530 1XTQ GDP 0.00000000008864 0.81131 47.4576
531 5JCZ GDP 0.00000000001331 0.68347 47.486
532 3SFV GDP 0.000000000003448 0.87217 47.5138
533 1Z08 GNP 0.00000000004166 0.61972 47.6471
534 1WA5 GTP 0.00000000008656 0.52921 47.7273
535 1S8F GDP 0.000000000009843 0.87207 48.0226
536 1Z0A GDP 0.000000000001133 0.87624 48.2759
537 4DKX GDP 0.0000000000004445 0.88381 48.4375
538 4LX0 BEF GDP 0.000000000006963 0.87622 48.5876
539 2HV8 GTP 0.000000000009329 0.86647 49.4186
540 4C4P GNP 0.000000000006649 0.87721 49.711
541 3NKV GNP 0.000000000006806 0.87323 49.7143
542 1G16 GDP 0.00000000002779 0.83221 50
Pocket No.: 2; Query (leader) PDB : 2CJW; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2cjw.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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