Receptor
PDB id Resolution Class Description Source Keywords
2CTC 1.4 Å EC: 3.4.17.1 THE HIGH RESOLUTION CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE BOS TAURUS HYDROLASE(C-TERMINAL PEPTIDASE)
Ref.: HIGH-RESOLUTION STRUCTURE OF THE COMPLEX BETWEEN CARBOXYPEPTIDASE A AND L-PHENYL LACTATE. ACTA CRYSTALLOGR.,SECT.D V. 49 534 1993
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
HFA A:309;
 Valid;
 none;
 Ki = 0.13 mM
166.174 C9 H10 O3 c1ccc...
ZN A:308;
 Part of Protein;
 none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
7CPA 2 Å EC: 3.4.17.1 COMPARISON OF THE STRUCTURES OF THREE CARBOXYPEPTIDASE A- PHOSPHONATE COMPLEXES DETERMINED BY X-RAY CRYSTALLOGRAPHY BOS TAURUS HYDROLASE(C-TERMINAL PEPTIDASE)
Ref.: COMPARISON OF THE STRUCTURES OF THREE CARBOXYPEPTIDASE A-PHOSPHONATE COMPLEXES DETERMINED BY X-RAY CRYSTALLOGRAPHY. BIOCHEMISTRY V. 30 8171 1991
Members (14)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3CPA - GLY TYR n/a n/a
2 1F57 Ki = 2.3 uM DCY C3 H7 N O2 S C([C@H](C(....
3 1CPS Ki = 0.22 uM CPM C11 H16 N2 O2 S CS(=N)(=N)....
4 2CTC Ki = 0.13 mM HFA C9 H10 O3 c1ccc(cc1)....
5 2RFH Ki = 0.15 uM 23N C10 H11 N O4 c1ccc(cc1)....
6 1HDQ Ki = 1.5 uM INF C10 H12 N2 O4 c1ccc(cc1)....
7 1IY7 Ki = 0.64 uM CXA C9 H12 N2 O4 S c1ccc(cc1)....
8 3FX6 Ki = 0.16 uM BPX C12 H15 N O6 c1ccc(cc1)....
9 8CPA Ki = 710 pM AGF C21 H25 N2 O8 P C[C@@H](C(....
10 1HEE Ki = 4.6 uM LHY C10 H12 N2 O4 c1ccc(cc1)....
11 1HDU Ki = 19 uM ING C10 H12 N2 O3 c1ccc(cc1)....
12 7CPA Ki = 11 fM FVF C30 H35 N2 O8 P CC(C)[C@H]....
13 6CPA Ki = 3 pM ZAF C22 H27 N2 O8 P C[C@@H](C(....
14 1CBX Ki = 0.45 uM BZS C11 H12 O4 c1ccc(cc1)....
70% Homology Family (17)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3CPA - GLY TYR n/a n/a
2 1F57 Ki = 2.3 uM DCY C3 H7 N O2 S C([C@H](C(....
3 1CPS Ki = 0.22 uM CPM C11 H16 N2 O2 S CS(=N)(=N)....
4 2CTC Ki = 0.13 mM HFA C9 H10 O3 c1ccc(cc1)....
5 2RFH Ki = 0.15 uM 23N C10 H11 N O4 c1ccc(cc1)....
6 1HDQ Ki = 1.5 uM INF C10 H12 N2 O4 c1ccc(cc1)....
7 1IY7 Ki = 0.64 uM CXA C9 H12 N2 O4 S c1ccc(cc1)....
8 3FX6 Ki = 0.16 uM BPX C12 H15 N O6 c1ccc(cc1)....
9 8CPA Ki = 710 pM AGF C21 H25 N2 O8 P C[C@@H](C(....
10 1HEE Ki = 4.6 uM LHY C10 H12 N2 O4 c1ccc(cc1)....
11 1HDU Ki = 19 uM ING C10 H12 N2 O3 c1ccc(cc1)....
12 7CPA Ki = 11 fM FVF C30 H35 N2 O8 P CC(C)[C@H]....
13 6CPA Ki = 3 pM ZAF C22 H27 N2 O8 P C[C@@H](C(....
14 1CBX Ki = 0.45 uM BZS C11 H12 O4 c1ccc(cc1)....
15 1PCA - VAL C5 H11 N O2 CC(C)[C@@H....
16 2PCU - PHE ASN ARG PRO VAL n/a n/a
17 2V77 Ki = 8.7 uM PAY C12 H18 O8 C[C@@H](C[....
50% Homology Family (47)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 223 families.
1 1NSA - BEN C7 H8 N2 [H]/N=C(c1....
2 4UIB ic50 = 0.001 uM GWX C26 H46 N4 O4 C[C@@]12CC....
3 2PIZ ic50 = 170 nM 606 C19 H24 N3 O4 P [H]/N=C(/N....
4 5LRG - 73N DLY VAL 73O MAA PHE n/a n/a
5 1ZG7 - P20 C10 H12 Cl N3 O2 S c1cc(c(cc1....
6 2PJ4 ic50 = 13 nM 414 C24 H31 N4 O7 P [H]/N=C(/N....
7 2PJ8 ic50 = 18 nM 17A C26 H31 N2 O6 P S CC(C)[C@H]....
8 4UIA ic50 = 0.19 uM FH9 C21 H40 N4 O4 CC(C)CCNC(....
9 2PJ9 ic50 = 12 nM 281 C20 H25 N4 O6 P S2 CC(C)[C@H]....
10 1ZG9 - L06 C7 H15 N3 O2 S C(C[C@@H](....
11 2JEW Ki = 206 nM 720 C12 H21 N3 O2 CCCn1cc(nc....
12 2PJ5 ic50 = 15 nM 11B C23 H31 N4 O7 P [H]/N=C(/N....
13 3WC5 - DDK C8 H17 N O2 Se C(CC[C@@H]....
14 2PJC ic50 = 1.9 nM 343 C30 H36 N5 O9 P [H]/N=C(/N....
15 2PJA ic50 = 2.2 nM 33Z C31 H38 N5 O7 P [H]/N=C(/N....
16 1ZG8 - L98 C10 H13 N3 O2 S c1cc(cc(c1....
17 3WC7 - EF1 C21 H35 N2 O5 P CC(C)[C@H]....
18 2PJ2 ic50 = 12 nM 864 C22 H29 N2 O6 P CC(C)[C@H]....
19 5LRK - 73N DLY IIL 73O MAA PHE n/a n/a
20 2PJ3 ic50 = 6.6 nM 86A C22 H29 N4 O6 P [H]/N=C(/N....
21 2PIY ic50 = 20 nM 528 C23 H33 N2 O6 P S CC(C)[C@H]....
22 2PJ0 ic50 = 8.1 nM 922 C21 H27 N4 O7 P [H]/N=C(/N....
23 3WAB - DDW C8 H17 N O2 S C(CC[C@@H]....
24 2PJB ic50 = 19 nM 983 C31 H40 N3 O8 P S CC(C)[C@H]....
25 2PJ1 ic50 = 9.7 nM 578 C21 H27 N2 O7 P CC(C)[C@H]....
26 5LRJ - 73P DLY VAL 73O MAA PHE n/a n/a
27 2PJ6 ic50 = 49 nM 059 C22 H31 N2 O6 P S CC(C)[C@H]....
28 5ZEQ - 9B3 C9 H11 Cl N2 O2 Se c1c(cnc(c1....
29 2PJ7 ic50 = 17 nM 235 C20 H27 N2 O6 P S CC(C)[C@H]....
30 3CPA - GLY TYR n/a n/a
31 1F57 Ki = 2.3 uM DCY C3 H7 N O2 S C([C@H](C(....
32 1CPS Ki = 0.22 uM CPM C11 H16 N2 O2 S CS(=N)(=N)....
33 2CTC Ki = 0.13 mM HFA C9 H10 O3 c1ccc(cc1)....
34 2RFH Ki = 0.15 uM 23N C10 H11 N O4 c1ccc(cc1)....
35 1HDQ Ki = 1.5 uM INF C10 H12 N2 O4 c1ccc(cc1)....
36 1IY7 Ki = 0.64 uM CXA C9 H12 N2 O4 S c1ccc(cc1)....
37 3FX6 Ki = 0.16 uM BPX C12 H15 N O6 c1ccc(cc1)....
38 8CPA Ki = 710 pM AGF C21 H25 N2 O8 P C[C@@H](C(....
39 1HEE Ki = 4.6 uM LHY C10 H12 N2 O4 c1ccc(cc1)....
40 1HDU Ki = 19 uM ING C10 H12 N2 O3 c1ccc(cc1)....
41 7CPA Ki = 11 fM FVF C30 H35 N2 O8 P CC(C)[C@H]....
42 6CPA Ki = 3 pM ZAF C22 H27 N2 O8 P C[C@@H](C(....
43 1CBX Ki = 0.45 uM BZS C11 H12 O4 c1ccc(cc1)....
44 1PCA - VAL C5 H11 N O2 CC(C)[C@@H....
45 4P10 - 2B8 C14 H23 N3 O2 CCCn1cnc2c....
46 2PCU - PHE ASN ARG PRO VAL n/a n/a
47 2V77 Ki = 8.7 uM PAY C12 H18 O8 C[C@@H](C[....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: HFA; Similar ligands found: 7
No: Ligand ECFP6 Tc MDL keys Tc
1 HF2 1 1
2 HFA 1 1
3 34H 0.552632 0.826087
4 BZS 0.512195 0.727273
5 PAC 0.432432 0.684211
6 PPY 0.410256 0.8
7 HCI 0.4 0.65
Similar Ligands (3D)
Ligand no: 1; Ligand: HFA; Similar ligands found: 836
No: Ligand Similarity coefficient
1 PHE 1.0000
2 NFA 0.9930
3 4LV 0.9925
4 AOT 0.9850
5 HIS 0.9811
6 4LW 0.9803
7 SHI 0.9780
8 S2P 0.9762
9 DPN 0.9710
10 BNL 0.9708
11 TYR 0.9702
12 DYT 0.9701
13 56D 0.9688
14 4ZD 0.9679
15 B3U 0.9670
16 DTY 0.9670
17 0A9 0.9662
18 ISA 0.9660
19 K7M 0.9658
20 TIH 0.9642
21 B40 0.9640
22 PFF 0.9637
23 M74 0.9636
24 HIC 0.9630
25 3CR 0.9629
26 4BF 0.9622
27 ENO 0.9616
28 M6H 0.9615
29 PO6 0.9612
30 BRH 0.9611
31 TYC 0.9609
32 33S 0.9601
33 LVD 0.9589
34 EN1 0.9588
35 HHI 0.9576
36 PCS 0.9570
37 CXP 0.9559
38 DHI 0.9556
39 TCA 0.9551
40 PHI 0.9550
41 MMS 0.9525
42 3QM 0.9517
43 AMQ 0.9517
44 P80 0.9513
45 HJH 0.9509
46 CLT 0.9504
47 XIZ 0.9488
48 TYE 0.9484
49 YOF 0.9480
50 DAH 0.9474
51 PBA 0.9463
52 R2P 0.9456
53 P58 0.9444
54 HNK 0.9434
55 FHC 0.9431
56 P7Y 0.9425
57 RQD 0.9425
58 NCT 0.9423
59 DIR 0.9422
60 PTU 0.9413
61 QUS 0.9413
62 1L5 0.9404
63 RLG 0.9400
64 PPT 0.9391
65 4XF 0.9389
66 PBN 0.9388
67 PRA 0.9387
68 UN1 0.9386
69 173 0.9384
70 APG 0.9383
71 PH3 0.9383
72 GLN 0.9380
73 R9J 0.9378
74 N4B 0.9378
75 2UB 0.9374
76 IYR 0.9373
77 URO 0.9372
78 2HC 0.9371
79 FK8 0.9369
80 HX4 0.9364
81 MSR 0.9363
82 R9M 0.9362
83 HC4 0.9356
84 J0Z 0.9352
85 3VW 0.9347
86 PMF 0.9345
87 Q04 0.9341
88 E0O 0.9341
89 S0W 0.9336
90 HSO 0.9335
91 3H2 0.9333
92 LT1 0.9333
93 7VP 0.9329
94 DXG 0.9328
95 ARG 0.9326
96 F06 0.9317
97 9RH 0.9312
98 3YP 0.9312
99 HL4 0.9306
100 7Q1 0.9300
101 AKG 0.9298
102 Z70 0.9297
103 1BN 0.9297
104 SNU 0.9293
105 F90 0.9285
106 TB8 0.9285
107 4TB 0.9280
108 7OD 0.9270
109 N9J 0.9270
110 0BP 0.9268
111 B85 0.9267
112 M3H 0.9267
113 HWD 0.9265
114 QMP 0.9265
115 YZM 0.9263
116 SYC 0.9263
117 GCO 0.9262
118 MES 0.9262
119 SMN 0.9261
120 Q03 0.9261
121 PIM 0.9259
122 ESX 0.9257
123 3PG 0.9256
124 BNF 0.9255
125 6FZ 0.9251
126 HNL 0.9248
127 11C 0.9248
128 HHH 0.9247
129 GT4 0.9246
130 GLR 0.9243
131 GVG 0.9242
132 I4B 0.9241
133 9B3 0.9241
134 DHC 0.9241
135 Y4L 0.9237
136 CPZ 0.9237
137 2D8 0.9236
138 HPP 0.9234
139 3LR 0.9234
140 ICB 0.9233
141 M5E 0.9230
142 4PN 0.9229
143 C53 0.9228
144 8OZ 0.9226
145 AHN 0.9224
146 AHC 0.9220
147 JF6 0.9217
148 XDK 0.9216
149 M45 0.9216
150 4SX 0.9215
151 7QS 0.9210
152 C82 0.9209
153 Q02 0.9207
154 7R4 0.9205
155 BZ2 0.9205
156 F4E 0.9205
157 7MK 0.9204
158 FTV 0.9203
159 EQW 0.9203
160 DE5 0.9203
161 JRB 0.9202
162 HNH 0.9200
163 F9P 0.9197
164 LY0 0.9197
165 HPS 0.9196
166 TOH 0.9191
167 LSQ 0.9189
168 HXY 0.9185
169 FBM 0.9183
170 KDG 0.9183
171 EVF 0.9181
172 36E 0.9181
173 BPW 0.9180
174 A09 0.9180
175 0NX 0.9176
176 9RW 0.9174
177 LGT 0.9173
178 TZM 0.9172
179 RMN 0.9172
180 QH3 0.9171
181 BPY 0.9166
182 RUY 0.9164
183 S7A 0.9163
184 RJY 0.9162
185 2FM 0.9161
186 Q06 0.9161
187 JZA 0.9160
188 MF3 0.9159
189 L13 0.9158
190 SAN 0.9157
191 9YT 0.9157
192 ESP 0.9155
193 PIY 0.9151
194 TYL 0.9150
195 264 0.9150
196 BTM 0.9149
197 GNW 0.9149
198 8U3 0.9148
199 CFI 0.9148
200 GRO 0.9147
201 268 0.9146
202 QY9 0.9146
203 IPO 0.9143
204 C1M 0.9139
205 J9N 0.9138
206 KYN 0.9137
207 4WL 0.9136
208 7UZ 0.9136
209 SAF 0.9136
210 CS2 0.9136
211 LLH 0.9135
212 XRS 0.9134
213 92G 0.9134
214 6ZX 0.9133
215 LFC 0.9133
216 GLU 0.9132
217 4P5 0.9128
218 KTJ 0.9124
219 ONL 0.9124
220 IWT 0.9124
221 R20 0.9123
222 A5E 0.9123
223 CXH 0.9120
224 EKZ 0.9119
225 4J8 0.9117
226 OGA 0.9115
227 3QO 0.9115
228 1PS 0.9111
229 Q9Z 0.9110
230 CWD 0.9110
231 O45 0.9106
232 1Z6 0.9106
233 NNH 0.9106
234 1SA 0.9106
235 X0V 0.9103
236 LNR 0.9103
237 PHU 0.9102
238 CLU 0.9102
239 5WZ 0.9101
240 3BU 0.9101
241 263 0.9101
242 ALE 0.9098
243 FWD 0.9097
244 0A1 0.9096
245 2LT 0.9096
246 OOG 0.9094
247 D3G 0.9092
248 NYL 0.9092
249 HG3 0.9088
250 TT4 0.9087
251 GWM 0.9087
252 TZF 0.9086
253 MNN 0.9084
254 BP3 0.9084
255 4ZA 0.9084
256 61M 0.9082
257 S8V 0.9080
258 LYS 0.9080
259 13P 0.9080
260 2C2 0.9079
261 HGA 0.9077
262 AEG 0.9077
263 DZA 0.9076
264 6NT 0.9075
265 KTA 0.9074
266 HQJ 0.9074
267 DGL 0.9073
268 IAR 0.9073
269 DAR 0.9073
270 P81 0.9073
271 IWD 0.9073
272 CH9 0.9073
273 SD4 0.9068
274 4HP 0.9066
275 49F 0.9065
276 46P 0.9065
277 CK2 0.9064
278 BWD 0.9064
279 X48 0.9062
280 3PF 0.9062
281 DGN 0.9059
282 IC9 0.9058
283 2HG 0.9057
284 BHO 0.9057
285 7BC 0.9053
286 AMS 0.9052
287 E79 0.9052
288 IVL 0.9052
289 GZ2 0.9051
290 1X4 0.9049
291 A29 0.9049
292 SYM 0.9047
293 RP3 0.9046
294 GAE 0.9046
295 BP7 0.9043
296 1A7 0.9040
297 2B4 0.9040
298 TSU 0.9040
299 CFA 0.9037
300 92K 0.9037
301 MPV 0.9037
302 258 0.9036
303 LL2 0.9035
304 23J 0.9035
305 M4T 0.9034
306 50C 0.9033
307 S3C 0.9033
308 FCR 0.9032
309 3HP 0.9031
310 URS 0.9026
311 IFP 0.9025
312 36M 0.9022
313 CCU 0.9021
314 EQA 0.9020
315 S2G 0.9020
316 6TZ 0.9020
317 XCG 0.9018
318 6J5 0.9017
319 M72 0.9016
320 GPF 0.9016
321 I1E 0.9015
322 1WC 0.9014
323 FZM 0.9014
324 YIE 0.9011
325 1DJ 0.9011
326 RAT 0.9007
327 2ZM 0.9004
328 GJZ 0.9003
329 TZP 0.9003
330 3C4 0.9003
331 K80 0.9002
332 2IT 0.9001
333 SEP 0.9001
334 SB7 0.9000
335 B2Y 0.8998
336 PF1 0.8998
337 DC5 0.8997
338 0OC 0.8996
339 3GZ 0.8995
340 9W5 0.8995
341 HJ8 0.8993
342 5LA 0.8992
343 36Y 0.8991
344 ALA ALA 0.8990
345 NIZ 0.8990
346 9ZE 0.8990
347 MEQ 0.8989
348 GO2 0.8988
349 ISZ 0.8987
350 TMG 0.8986
351 BZE 0.8983
352 TPA 0.8982
353 5NI 0.8982
354 DHY 0.8981
355 4VY 0.8980
356 HDL 0.8980
357 DLY 0.8979
358 0HN 0.8979
359 269 0.8978
360 2F6 0.8976
361 OTR 0.8975
362 GGL 0.8975
363 8GL 0.8974
364 N2Y 0.8974
365 BY5 0.8974
366 1VK 0.8971
367 XYH 0.8970
368 ESI 0.8969
369 DEW 0.8968
370 TRP 0.8968
371 5DL 0.8967
372 L5V 0.8967
373 SOJ 0.8967
374 L22 0.8967
375 R9S 0.8965
376 4FP 0.8964
377 1F1 0.8963
378 1SV 0.8963
379 DHB 0.8962
380 6HO 0.8962
381 AVI 0.8962
382 RNT 0.8962
383 MXN 0.8961
384 9ON 0.8960
385 TOM 0.8960
386 4NB 0.8959
387 HA5 0.8957
388 N2Z 0.8956
389 YPN 0.8956
390 C0H 0.8953
391 1XA 0.8953
392 SQ4 0.8952
393 MPK 0.8951
394 EDR 0.8951
395 4CF 0.8951
396 MXD 0.8951
397 3NY 0.8948
398 OSE 0.8947
399 DI6 0.8945
400 F16 0.8944
401 2JJ 0.8944
402 7C3 0.8944
403 L99 0.8943
404 NFM 0.8939
405 FB2 0.8939
406 KPA 0.8934
407 5OO 0.8934
408 A3M 0.8934
409 5QY 0.8933
410 GB5 0.8932
411 4BY 0.8932
412 J6W 0.8932
413 9FL 0.8931
414 HPV 0.8931
415 XQI 0.8930
416 IZC 0.8929
417 GUA 0.8929
418 OHP 0.8926
419 EXD 0.8925
420 52C 0.8925
421 FEH 0.8924
422 4NC 0.8922
423 4Z3 0.8922
424 PHB 0.8921
425 GGB 0.8921
426 J4K 0.8921
427 GLO 0.8919
428 PMB 0.8919
429 DAL DAL 0.8918
430 1M2 0.8916
431 0JD 0.8915
432 ICO 0.8915
433 ENV 0.8915
434 K6H 0.8913
435 XRX 0.8913
436 FF3 0.8910
437 SDD 0.8910
438 FUD 0.8909
439 PJW 0.8909
440 7UC 0.8909
441 PEP 0.8907
442 XIY 0.8907
443 RNS 0.8904
444 AL0 0.8903
445 E4P 0.8903
446 CK1 0.8902
447 505 0.8902
448 AAN 0.8900
449 IAC 0.8898
450 SOR 0.8897
451 MTL 0.8896
452 SPA 0.8896
453 6NI 0.8895
454 MHO 0.8895
455 5XB 0.8894
456 GPJ 0.8894
457 KJU 0.8893
458 9PL 0.8892
459 YIP 0.8891
460 DE3 0.8889
461 6J9 0.8888
462 SLS 0.8886
463 DEZ 0.8886
464 4FH 0.8885
465 HSX 0.8885
466 SPV 0.8885
467 MP5 0.8885
468 MUC 0.8884
469 NVU 0.8884
470 G3H 0.8883
471 G3P 0.8883
472 QBS 0.8882
473 DTR 0.8882
474 T2D 0.8880
475 ZGL 0.8880
476 N3W 0.8880
477 TAG 0.8880
478 AAS 0.8880
479 152 0.8879
480 ERZ 0.8878
481 EYV 0.8875
482 791 0.8875
483 JAW 0.8875
484 LT2 0.8875
485 363 0.8873
486 F4K 0.8872
487 15N 0.8871
488 97T 0.8870
489 XCZ 0.8869
490 RNO 0.8868
491 FF2 0.8868
492 ASC 0.8865
493 K34 0.8864
494 3ZB 0.8862
495 HMS 0.8861
496 MAJ 0.8860
497 12T 0.8860
498 FAN 0.8859
499 KMH 0.8859
500 AVJ 0.8859
501 PEA 0.8858
502 BZQ 0.8858
503 2FT 0.8856
504 54F 0.8852
505 J9Q 0.8851
506 GZ3 0.8848
507 A9P 0.8848
508 ODK 0.8847
509 E3X 0.8846
510 S0F 0.8846
511 0HO 0.8846
512 2FX 0.8845
513 FPL 0.8844
514 B09 0.8844
515 LDP 0.8844
516 TSR 0.8842
517 LTT 0.8842
518 AMH 0.8842
519 TPO 0.8840
520 HX8 0.8839
521 M3P 0.8837
522 KMY 0.8837
523 FOC 0.8836
524 C5A 0.8835
525 PUE 0.8834
526 3HG 0.8834
527 4V2 0.8833
528 DS0 0.8832
529 ABF 0.8831
530 LNO 0.8831
531 LQ2 0.8826
532 J9T 0.8826
533 SSC 0.8826
534 SNO 0.8824
535 PGH 0.8824
536 650 0.8823
537 RP5 0.8823
538 3SL 0.8823
539 MAH 0.8822
540 M2K 0.8821
541 S7J 0.8820
542 HDH 0.8819
543 5RN 0.8819
544 CCE 0.8818
545 LTN 0.8817
546 API 0.8817
547 FBS 0.8816
548 E1P 0.8815
549 5VL 0.8815
550 GVY 0.8815
551 4JQ 0.8814
552 HY1 0.8812
553 DCZ 0.8812
554 XDE 0.8812
555 BEZ 0.8810
556 C2Y 0.8810
557 0F9 0.8810
558 1GP 0.8810
559 PSJ 0.8810
560 ZZ2 0.8810
561 795 0.8809
562 LPK 0.8809
563 0OL 0.8809
564 OKG 0.8808
565 DXP 0.8808
566 TZL 0.8807
567 K97 0.8807
568 4FA 0.8807
569 6M4 0.8806
570 6Q3 0.8803
571 PPR 0.8803
572 M1Z 0.8803
573 4JT 0.8799
574 2QC 0.8799
575 2BX 0.8798
576 ABI 0.8797
577 QIV 0.8796
578 0QW 0.8795
579 CUW 0.8795
580 SOL 0.8794
581 069 0.8794
582 8XL 0.8793
583 3A9 0.8791
584 F52 0.8791
585 G14 0.8789
586 PC 0.8788
587 PZI 0.8788
588 DER 0.8788
589 THU 0.8787
590 SV4 0.8787
591 5OB 0.8787
592 ZEC 0.8786
593 BQ2 0.8786
594 YRL 0.8785
595 XXP 0.8784
596 B41 0.8782
597 HL5 0.8782
598 11X 0.8782
599 AG2 0.8781
600 AEF 0.8781
601 0VT 0.8780
602 6KT 0.8780
603 2BG 0.8780
604 UNJ 0.8778
605 FBF 0.8778
606 AX3 0.8776
607 L14 0.8775
608 4RW 0.8775
609 SLY 0.8775
610 S24 0.8774
611 SBK 0.8772
612 TLM 0.8771
613 3IL 0.8771
614 I2E 0.8770
615 8EW 0.8768
616 W29 0.8765
617 JB8 0.8764
618 OMD 0.8764
619 IOS 0.8764
620 XBT 0.8764
621 PJL 0.8764
622 6L6 0.8763
623 OEG 0.8761
624 E1T 0.8759
625 CIR 0.8755
626 4BL 0.8752
627 TU0 0.8752
628 XI7 0.8751
629 OIA 0.8751
630 FA1 0.8751
631 ILO 0.8751
632 M5H 0.8751
633 80G 0.8750
634 9GB 0.8749
635 ORN 0.8748
636 9SE 0.8748
637 DDU 0.8747
638 HQ9 0.8746
639 JDN 0.8746
640 FMQ 0.8745
641 SME 0.8745
642 4OG 0.8745
643 BCU 0.8745
644 X11 0.8745
645 PEQ 0.8744
646 271 0.8743
647 GRF 0.8741
648 SSB 0.8740
649 BHH 0.8740
650 8WO 0.8739
651 FBV 0.8739
652 ONH 0.8739
653 MJ5 0.8738
654 EOU 0.8737
655 URP 0.8737
656 PEL 0.8735
657 PAU 0.8734
658 PLU 0.8734
659 3VX 0.8732
660 4NG 0.8730
661 XXG 0.8727
662 7MU 0.8726
663 CHH 0.8726
664 KTW 0.8726
665 ZZA 0.8724
666 2AL 0.8724
667 GZL 0.8723
668 UA5 0.8723
669 2CL 0.8721
670 LPB 0.8721
671 4Z9 0.8720
672 9BF 0.8720
673 AOS 0.8716
674 AT3 0.8716
675 AC6 0.8715
676 5RO 0.8714
677 CEE 0.8714
678 ZZU 0.8713
679 GLY GLY 0.8710
680 DNB 0.8709
681 1Z8 0.8708
682 IP8 0.8706
683 JAH 0.8706
684 1FD 0.8703
685 7N0 0.8702
686 5GU 0.8701
687 XUL 0.8700
688 MR1 0.8700
689 5XC 0.8700
690 FBW 0.8699
691 2HU 0.8699
692 GVM 0.8699
693 HBU 0.8698
694 8ZE 0.8698
695 GP9 0.8697
696 K5W 0.8695
697 ONR 0.8695
698 M3E 0.8694
699 CXF 0.8694
700 MQB 0.8693
701 D48 0.8693
702 7O4 0.8692
703 SWX 0.8691
704 STT 0.8689
705 L06 0.8689
706 7ZL 0.8689
707 2O6 0.8689
708 S0E 0.8687
709 2LY 0.8687
710 3TC 0.8686
711 41K 0.8685
712 ACH 0.8685
713 BZJ 0.8683
714 14W 0.8682
715 MZT 0.8682
716 0V5 0.8681
717 LR5 0.8679
718 DUR 0.8679
719 PQT 0.8677
720 0W1 0.8676
721 KPC 0.8673
722 FOM 0.8672
723 BCK 0.8671
724 H4E 0.8670
725 PGA 0.8670
726 H42 0.8670
727 IOP 0.8669
728 9FH 0.8667
729 BZ3 0.8666
730 JVN 0.8666
731 JF2 0.8666
732 DHM 0.8665
733 MWP 0.8664
734 B4O 0.8664
735 3AE 0.8664
736 AFS 0.8664
737 PLP 0.8664
738 T03 0.8663
739 40F 0.8663
740 X0U 0.8662
741 DHS 0.8659
742 GBN 0.8659
743 B1J 0.8659
744 YTX 0.8658
745 TR7 0.8656
746 CCD 0.8654
747 92P 0.8653
748 9CA 0.8652
749 XLS 0.8651
750 DHK 0.8651
751 M6W 0.8650
752 GOJ 0.8650
753 4TU 0.8647
754 LJ3 0.8646
755 JPQ 0.8644
756 DTE 0.8644
757 I3A 0.8643
758 1KN 0.8642
759 NHG 0.8641
760 L5E 0.8640
761 LMR 0.8640
762 COU 0.8639
763 091 0.8639
764 G3E 0.8639
765 OCH 0.8638
766 FER 0.8636
767 OA1 0.8636
768 TSS 0.8636
769 6HX 0.8632
770 4LR 0.8631
771 SKM 0.8630
772 9R5 0.8629
773 DHZ 0.8629
774 SDF 0.8627
775 HIO 0.8625
776 N6C 0.8623
777 RBJ 0.8622
778 2PG 0.8622
779 42J 0.8621
780 I3E 0.8619
781 OAA 0.8619
782 N1E 0.8615
783 DHR 0.8615
784 CTS 0.8615
785 BVA 0.8614
786 N91 0.8610
787 0FK 0.8609
788 F69 0.8609
789 DBX 0.8609
790 KLS 0.8608
791 A5P 0.8607
792 129 0.8606
793 1IT 0.8605
794 4AF 0.8604
795 NM3 0.8604
796 5GT 0.8603
797 HNM 0.8603
798 SKF 0.8600
799 N2I 0.8599
800 ZIQ 0.8598
801 BNS 0.8597
802 JZ7 0.8595
803 VXX 0.8594
804 EGR 0.8591
805 3R4 0.8590
806 N7I 0.8588
807 51R 0.8586
808 MT2 0.8585
809 1YO 0.8584
810 E7Z 0.8581
811 54E 0.8579
812 6DP 0.8574
813 3S5 0.8574
814 A7Q 0.8572
815 ZBT 0.8572
816 49O 0.8570
817 EYJ 0.8568
818 SE2 0.8563
819 XK0 0.8561
820 4NS 0.8560
821 5O5 0.8559
822 E5X 0.8556
823 YIH 0.8555
824 HPT 0.8555
825 CYX 0.8554
826 4NZ 0.8553
827 A9O 0.8550
828 64Z 0.8549
829 SWA 0.8545
830 XYL 0.8544
831 SG3 0.8544
832 AN3 0.8540
833 4I8 0.8533
834 ASN 0.8532
835 SKJ 0.8531
836 RVE 0.8511
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 7CPA; Ligand: FVF; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 7cpa.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
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