Receptor
PDB id Resolution Class Description Source Keywords
2D7C 1.75 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF HUMAN RAB11 IN COMPLEX WITH FIP3 RAB- BINDING DOMAIN HOMO SAPIENS GTP-ASE COILED-COIL PROTEIN TRANSPORT
Ref.: STRUCTURAL BASIS FOR RAB11-DEPENDENT MEMBRANE RECRUITMENT OF A FAMILY OF RAB11-INTERACTING PROTEIN 3 (FIP3)/ARFOPHILIN-1. PROC.NATL.ACAD.SCI.USA V. 103 15416 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GTP A:1001;
B:1101;
Valid;
Valid;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MES A:1;
Invalid;
none;
submit data
195.237 C6 H13 N O4 S C1COC...
MG A:1002;
B:1102;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2D7C 1.75 Å EC: 3.-.-.- CRYSTAL STRUCTURE OF HUMAN RAB11 IN COMPLEX WITH FIP3 RAB- BINDING DOMAIN HOMO SAPIENS GTP-ASE COILED-COIL PROTEIN TRANSPORT
Ref.: STRUCTURAL BASIS FOR RAB11-DEPENDENT MEMBRANE RECRUITMENT OF A FAMILY OF RAB11-INTERACTING PROTEIN 3 (FIP3)/ARFOPHILIN-1. PROC.NATL.ACAD.SCI.USA V. 103 15416 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 218 families.
1 2D7C - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 176 families.
1 2D7C - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 143 families.
1 2HV8 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
2 2D7C - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2D7C; Ligand: GTP; Similar sites found: 449
This union binding pocket(no: 1) in the query (biounit: 2d7c.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1Y63 ADP 0.000009018 0.57078 None
2 3IIJ ADP 0.000009857 0.56887 None
3 5AOG IAC 0.0184 0.44937 None
4 1ION ADP 0.00006987 0.42659 None
5 3H86 AP5 0.00209 0.42624 None
6 2O66 FLC 0.01528 0.42139 None
7 2DT9 THR 0.02558 0.40377 None
8 3DC4 ADP 0.0000008116 0.64205 0.598802
9 1V8K ANP 0.0000002845 0.64493 1.79641
10 1NU4 MLA 0.04373 0.40336 2.06186
11 3U6B GDP 0.0000000001078 0.82827 2.39521
12 4J0Q GDP 0.0000000001926 0.81551 2.39521
13 3WY9 GDP 0.0000000002224 0.81235 2.39521
14 5JBQ GDP 0.0000000003109 0.79124 2.39521
15 4G5G GDP 0.0000000003726 0.78735 2.39521
16 3U6K GDP 0.0000000004589 0.78288 2.39521
17 3WYA GDP 0.0000000006252 0.77625 2.39521
18 2BVN GNP 0.000000000371 0.75112 2.39521
19 2HCJ GDP 0.00000000008353 0.56967 2.39521
20 1D8T GDP 0.000000000321 0.56835 2.39521
21 5LB3 ADP 0.00003954 0.54643 2.39521
22 4R43 GDP 0.00006497 0.52841 2.39521
23 3BER AMP 0.003696 0.44167 2.39521
24 1APZ ASP 0.0145 0.42083 2.46914
25 1U0J ADP 0.0007522 0.48163 2.99401
26 5K5Z ANP 0.00008905 0.47374 2.99401
27 1NJF AGS 0.0002351 0.43795 2.99401
28 4Y4V DAL 0.008807 0.4329 2.99401
29 1NJF ADP 0.0001779 0.43022 2.99401
30 3H4S ADP 0.0000003481 0.42972 2.99401
31 4FRZ ADP 0.000001468 0.42901 2.99401
32 3FYH ADP 0.002234 0.41667 2.99401
33 4Z7X 3CX 0.04306 0.40339 2.99401
34 1XP8 AGS 0.0003274 0.49993 3.00546
35 1SQL GUN 0.02424 0.4079 3.42466
36 2W58 ADP 0.0000008272 0.66776 3.59281
37 2ZFI ADP 0.0000007441 0.62431 3.59281
38 1SQ5 ADP 0.00006186 0.52277 3.59281
39 5FTB ANP 0.0002047 0.49197 3.59281
40 5FHD ADP ALF 0.0003568 0.46139 3.59281
41 2ZTS ADP 0.0006769 0.45356 3.59281
42 2VVG ADP 0.00000009248 0.43044 3.59281
43 1BG2 ADP 0.0000003057 0.41791 3.59281
44 1JS8 MAN MAN BMA 0.02012 0.41236 3.59281
45 2C78 GNP 0.0000000002501 0.71799 4.19162
46 2XT3 ADP 0.0000002157 0.68886 4.19162
47 4LPS GDP 0.00000003252 0.68093 4.19162
48 2C77 GNP 0.0000000001905 0.65538 4.19162
49 4V03 ADP 0.00001327 0.54797 4.19162
50 4WOP CTP 0.00008022 0.48942 4.19162
51 1F9V ADP 0.000001226 0.42998 4.19162
52 4WEI GLC GAL 0.01283 0.41861 4.19162
53 1BO4 COA 0.01461 0.41206 4.19162
54 1OXV ANP 0.0000258 0.40746 4.19162
55 2F5X ASP 0.0268 0.40682 4.19162
56 2ZWS PLM 0.03305 0.4009 4.19162
57 3FWY ADP 0.000008336 0.54407 4.79042
58 4ZNL BEF ADP 0.0001644 0.5023 4.79042
59 4C25 13P 0.009069 0.42677 4.79042
60 3FB4 AP5 0.00297 0.42569 4.79042
61 2WZF BGC 0.01425 0.423 4.79042
62 3QF7 ANP 0.002802 0.41703 4.79042
63 5X40 ACP 0.001136 0.41544 4.79042
64 5WRI A3P 0.005178 0.40785 4.79042
65 4EBZ NAG NAG NAG NAG 0.02511 0.40419 4.79042
66 2OFE NAG 0.03168 0.40332 4.92958
67 4PC3 GDP 0.00000001952 0.67181 5.38922
68 1JJ7 ADP 0.000002302 0.6422 5.38922
69 3BFV ADP 0.00002713 0.54714 5.38922
70 4D81 ADP 0.0001664 0.49068 5.38922
71 2GK6 ADP 0.00125 0.47632 5.38922
72 4U60 SIA GAL NGA 0.003535 0.45584 5.38922
73 4U60 SIA 0.004306 0.45101 5.38922
74 1W5T ADP 0.003665 0.42487 5.38922
75 1W5T ANP 0.002598 0.42409 5.38922
76 4P32 ADP 0.002627 0.42037 5.38922
77 1DNP MHF 0.03236 0.41355 5.38922
78 4K7O EKZ 0.02532 0.40989 5.38922
79 4U60 SIA GAL BGC NGA GAL 0.02562 0.40374 5.38922
80 1T5C ADP 0.0000009578 0.65734 5.98802
81 2NCD ADP 0.000001636 0.63389 5.98802
82 3B5J 12D 0.00006656 0.54255 5.98802
83 5I0H ADP BEF 0.0000003532 0.53388 5.98802
84 4RZ3 ADP 0.00002664 0.52132 5.98802
85 5J1J ANP 0.00002778 0.49915 5.98802
86 1NY5 ADP 0.0003329 0.47187 5.98802
87 1CR1 TTP 0.0003454 0.42415 5.98802
88 5H56 ADP 0.00208 0.42093 5.98802
89 5H56 TYD 0.00208 0.42093 5.98802
90 4GBM A3P 0.003233 0.41326 5.98802
91 3QXC ATP 0.001872 0.41127 5.98802
92 5XQL C2E 0.02416 0.40525 5.98802
93 4CP8 MLI 0.03121 0.4041 5.98802
94 2PEL LBT 0.03331 0.40184 5.98802
95 5MVR ADP 0.00004058 0.5385 6.17284
96 4RD0 GDP 0.00000000008717 0.73739 6.58683
97 2XTZ GSP 0.0000000001883 0.69659 6.58683
98 4R98 GNH 0.0000001683 0.6562 6.58683
99 1JI0 ATP 0.00003096 0.55983 6.58683
100 4QM7 GTP 0.00003227 0.54342 6.58683
101 3T34 GDP 0.000005039 0.52996 6.58683
102 3UIE ANP 0.00003429 0.52853 6.58683
103 2OBM ADP 0.0002271 0.52509 6.58683
104 4LYA ATP 0.00006352 0.52221 6.58683
105 3BOS CDP 0.0001662 0.50825 6.58683
106 3ZS9 ADP ALF 0.0000462 0.4736 6.58683
107 2WOJ ADP ALF 0.00004912 0.47257 6.58683
108 3FVQ ATP 0.0002216 0.47033 6.58683
109 4R2I ANP 0.002336 0.46219 6.58683
110 5M7P ADP 0.0006285 0.45498 6.58683
111 5E5U MLI 0.01178 0.44107 6.58683
112 2OFW ADX 0.00131 0.43961 6.58683
113 1L2T ATP 0.0006387 0.43885 6.58683
114 2PEZ DAT 0.001093 0.43523 6.58683
115 1KO8 6PG 0.0003678 0.41685 6.58683
116 5CKS 52L 0.01813 0.40359 6.58683
117 2IL4 COA 0.007868 0.41344 6.79612
118 1YRB GDP 0.0000000006648 0.73944 7.14286
119 2WHX ADP 0.00003267 0.56573 7.14286
120 5GVR LMR 0.0001241 0.53787 7.14286
121 2JLR ANP 0.0001662 0.49071 7.14286
122 1D2N ANP 0.0008774 0.44449 7.14286
123 1T3D CYS 0.009531 0.42517 7.14286
124 1X6V ADP 0.00116 0.40849 7.14286
125 3EWA ANP 0.00006654 0.40777 7.14286
126 2RCN GDP 0.00000000002265 0.84744 7.18563
127 4NCN GTP 0.00000000006058 0.73444 7.18563
128 1GOJ ADP 0.00000006556 0.72407 7.18563
129 4TMZ GSP 0.0000000003856 0.70103 7.18563
130 1SVK ALF GDP 0.000000001728 0.66925 7.18563
131 3CX8 GSP 0.0000000002882 0.65191 7.18563
132 2HF9 GSP 0.00000005481 0.64246 7.18563
133 1AZT GSP 0.000000001062 0.63158 7.18563
134 2ODE ALF GDP 0.000000001358 0.62758 7.18563
135 1BH2 GSP 0.000000001694 0.62391 7.18563
136 1FQJ GDP 0.00000005672 0.61095 7.18563
137 1ZCB GDP 0.00000007405 0.59277 7.18563
138 3AB3 GDP 0.00000001321 0.59066 7.18563
139 1Y3A GDP 0.0000002396 0.58494 7.18563
140 1FQJ ALF 0.00002103 0.57323 7.18563
141 2OM2 GDP 0.000001066 0.57057 7.18563
142 4YMU ATP 0.00003379 0.54989 7.18563
143 1G3Q ADP 0.00003194 0.53662 7.18563
144 4XTR ADP 0.00006101 0.4997 7.18563
145 1XMV ADP 0.000195 0.49872 7.18563
146 4QOS ADP 0.0002543 0.48752 7.18563
147 4XVU ATP 0.00006383 0.48413 7.18563
148 4XTR ATP 0.00006401 0.48408 7.18563
149 1LVG ADP 0.0000008937 0.43979 7.18563
150 3QKT ANP 0.001061 0.42987 7.18563
151 3BP1 GUN 0.02089 0.41364 7.18563
152 4FUA PGH 0.02113 0.41226 7.18563
153 1FNZ A2G 0.02595 0.41138 7.18563
154 4DCT GDP 0.0000000001427 0.79465 7.78443
155 1G6H ADP 0.000003588 0.63095 7.78443
156 3DEF GDP 0.000001471 0.58531 7.78443
157 4P4T GDP 0.0000007958 0.5829 7.78443
158 4E03 ADP 0.00004391 0.52995 7.78443
159 4UOX PLP 0.01883 0.4028 7.78443
160 4CVN ADP 0.000004299 0.6044 8.37696
161 4HI0 GDP 0.0000004834 0.58542 8.38323
162 4YDS ATP 0.00001583 0.57498 8.38323
163 4P3Y GDP 0.0000000001264 0.56583 8.38323
164 4NON GDP 0.0000001055 0.56484 8.38323
165 1G41 ADP 0.00007588 0.51228 8.38323
166 5VGR GDP 0.0002438 0.47797 8.38323
167 2FNA ADP 0.000287 0.46114 8.38323
168 1K4M CIT 0.04006 0.41335 8.38323
169 2WJH GDP 0.000000001111 0.57241 8.43373
170 2WJH FLC 0.0000002364 0.50558 8.43373
171 5IRN ADP 0.00006547 0.50935 8.98204
172 2Y65 ADP 0.0000009865 0.41991 8.98204
173 1HTW ADP 0.00003686 0.42616 9.49367
174 5XDR ADP 0.0002282 0.49543 9.52381
175 4IDN GNP 0.00008585 0.48336 9.52381
176 3KJI ADP 0.00002152 0.45167 9.52381
177 4A4Z ANP 0.002759 0.44795 9.52381
178 3IO3 ADP 0.00007001 0.44511 9.52381
179 5I34 GDP 0.00003315 0.53584 9.58084
180 3ZFD ANP 0.00000004117 0.5292 9.58084
181 1FP6 ADP 0.0000424 0.51805 9.58084
182 2VB6 ADP BEF 0.00001238 0.51374 9.58084
183 2C04 GCP 0.00006577 0.50362 9.58084
184 4IOK ADP 0.003073 0.41109 9.58084
185 4IOK XPO 0.002682 0.40626 9.58084
186 2DPY ADP 0.00003871 0.55479 10.1796
187 2VF7 ADP 0.0003716 0.48521 10.1796
188 2BIF SIN 0.002637 0.43103 10.1796
189 2BIF ANP 0.001491 0.43103 10.1796
190 4GOX A3P 0.001306 0.42964 10.1796
191 3GFS FMN 0.009626 0.41306 10.1796
192 4ZG4 VO4 ADP 0.000000759 0.56413 10.7784
193 4PX9 ADP 0.000054 0.53958 10.7784
194 3Q9L ATP 0.00005923 0.50568 10.7784
195 2ZJ5 ADP 0.0143 0.42305 10.7784
196 2I4I AMP 0.009725 0.4057 10.7784
197 3A1S GDP 0.0000003263 0.63263 11.3772
198 5J1S ATP 0.001322 0.42596 11.3821
199 3NHB ADP 0.00001129 0.58996 11.9048
200 3TBK ANP 0.0002151 0.51607 11.9048
201 4XGU ADP 0.0001975 0.48209 11.9048
202 4MKF AP5 0.003538 0.42352 11.9048
203 1VHT BA3 0.0008305 0.4633 11.976
204 5H67 ATP 0.002812 0.44279 11.976
205 2GWH A3P 0.008541 0.40825 11.976
206 2ZPA ADP 0.0003232 0.41879 12.5749
207 1NRJ GTP 0.000000000603 0.711 12.844
208 5CK5 GDP 0.0000000009327 0.78081 13.1737
209 1M2O GNP 0.00000000171 0.65825 13.1737
210 2QTV GNP 0.000000002428 0.64412 13.1737
211 2PL3 ADP 0.0001243 0.52123 13.1737
212 2Z5F A3P 0.006857 0.40582 13.1737
213 2WIC GNP 0.00000000625 0.71547 13.7725
214 1JJV ATP 0.0000441 0.55689 13.7725
215 3TK1 GDP 0.0000000004333 0.81217 14.2857
216 5IRR GSP 0.000000004827 0.6635 14.2857
217 4ZKD GDP 0.0000000007771 0.65789 14.2857
218 3B9Q MLI 0.00004035 0.55044 14.2857
219 2OG2 MLI 0.00002659 0.54708 14.2857
220 4HSE ADP 0.00003686 0.53361 14.2857
221 5LTJ BEF 0.0002691 0.52913 14.2857
222 5L3R GCP 0.000003963 0.52885 14.2857
223 5LTJ ADP 0.000058 0.52412 14.2857
224 1H65 GDP 0.00001504 0.51543 14.2857
225 4IEE AGS 0.0007288 0.48232 14.2857
226 1FNN ADP 0.0004498 0.4614 14.2857
227 1K6M AGS 0.0006185 0.44313 14.2857
228 4MKG AP5 0.003388 0.42326 14.2857
229 5G41 AP5 0.005275 0.42003 14.2857
230 2XAU ADP 0.000264 0.40311 14.2857
231 5M04 GDP 0.000000002559 0.75861 14.3713
232 4BAS GNP 0.000000001902 0.62979 14.3713
233 1M7G ADX 0.0005897 0.44482 14.3713
234 1M7G ADP 0.0007739 0.43693 14.3713
235 1M7G AV2 0.000004515 0.43391 14.3713
236 4PPF FLC 0.000005817 0.61369 14.9701
237 2ZR9 DTP 0.0001418 0.51167 14.9701
238 1GXU 2HP 0.00005024 0.54036 15.3846
239 1XEX ATP 0.003774 0.40439 15.5689
240 1G7C 5GP 0.000000205 0.65196 16.1677
241 1TQ4 GDP 0.00000004937 0.62827 16.6667
242 3EZ2 ADP 0.00009111 0.52807 16.6667
243 5BQ5 ADP BEF 0.0001214 0.50265 16.6667
244 1F5N GNP 0.00002508 0.48389 16.6667
245 1IHU AF3 0.00008618 0.48329 16.6667
246 1IHU ADP 0.0001097 0.47435 16.6667
247 3DZD ADP 0.0003791 0.4742 16.6667
248 2BEK ATP 0.0001973 0.46804 16.6667
249 1B0U ATP 0.0005301 0.46749 16.6667
250 1YTM ATP 0.0002606 0.46729 16.6667
251 1OYY AGS 0.001126 0.4672 16.6667
252 3COB ADP 0.0000002001 0.43677 16.6667
253 3P4X ADP 0.00001502 0.42297 16.6667
254 2KIN ADP 0.0000003579 0.41616 17
255 2WJG GDP 0.000000001555 0.7567 17.3653
256 2QZ4 ADP 0.00008756 0.50935 17.3653
257 1SKQ GDP 0.000000002185 0.76209 17.9641
258 2CBZ ATP 0.0000006691 0.67191 17.9641
259 1OFH ADP 0.0001078 0.42044 17.9641
260 1D2E GDP 0.00000001134 0.68268 18.5629
261 1F2U ATP 0.00165 0.41309 18.9189
262 2QN6 GDP 0.0000000001514 0.8208 19.0476
263 4B47 GDP 0.00000000026 0.80891 19.0476
264 1G7S GDP 0.000000004939 0.72041 19.0476
265 3LRE ADP 0.0000002946 0.68566 19.0476
266 3WXM GTP 0.000000001846 0.65692 19.0476
267 3DKP ADP 0.0001761 0.50702 19.0476
268 2FAH GDP 0.00008435 0.50428 19.0476
269 1XKV ATP 0.0001647 0.49641 19.0476
270 5HR5 ADP 0.0003101 0.47326 19.0476
271 1IN4 ADP 0.0003215 0.46784 19.0476
272 4YS0 ADP 0.0008996 0.4524 19.0476
273 1OS1 ATP 0.002015 0.40003 19.0476
274 5TSH ADP 0.0000116 0.58855 19.1617
275 1PUJ GNP 0.000000002876 0.57943 19.1617
276 5TSH ANP 0.00001579 0.55875 19.1617
277 5HCN GCP 0.000000003024 0.73068 19.7605
278 4BQS ADP 0.00006093 0.52979 19.7605
279 4OHY ANP 0.0002232 0.45747 19.7605
280 1W7J ADP BEF 0.000004272 0.55716 19.8675
281 1UJ2 C5P 0.002792 0.40379 20.9581
282 1UJ2 ADP 0.003415 0.40034 20.9581
283 2FH5 GTP 0.000000000002813 0.81181 21.4286
284 4H1V GNP 0.00000232 0.56912 21.4286
285 5GJC ATP 0.00004126 0.53815 21.4286
286 3ZIA ATP 0.00007554 0.51858 21.4286
287 2V7Q ATP 0.00006295 0.5161 21.4286
288 2V7Q ADP 0.0001313 0.51332 21.4286
289 2IS6 ADP 0.0001325 0.51311 21.4286
290 3ZIA ADP 0.0001709 0.49015 21.4286
291 1P9B GDP 0.0001978 0.48206 21.4286
292 2CK3 ANP 0.0006375 0.45471 21.4286
293 2CK3 ADP 0.000971 0.43499 21.4286
294 3BFX A3P 0.002757 0.42662 21.4286
295 1W0J ADP 0.00009949 0.42527 21.4286
296 1W0J ADP BEF 0.0005657 0.41196 21.4286
297 2CE7 ADP 0.0001862 0.40747 21.4286
298 1T8U A3P 0.007765 0.40347 21.4286
299 5EE5 GTP 0.000000000005355 0.78874 21.5569
300 1UPT GTP 0.00000000006963 0.74152 21.5569
301 4WZA ACP 0.00009247 0.50885 21.5569
302 4WZA ADP 0.00009792 0.50774 21.5569
303 2PZE ATP 0.000003531 0.40142 21.5569
304 1KK1 GNP 0.000000001008 0.7791 22.1557
305 1ZJ6 G3D 0.000000001324 0.74799 22.1557
306 2AWN ADP 0.0000001444 0.71985 22.1557
307 1F6B GDP 0.0000000184 0.69286 22.1557
308 3E70 GDP 0.000004557 0.5774 22.1557
309 1R0X ATP 0.0001623 0.40068 22.1557
310 3AQ4 GDP 0.000000002526 0.73445 22.7545
311 3A4M ADP 0.000004787 0.60198 22.7545
312 5N69 ADP 0.00001501 0.53883 23.8095
313 3FKQ ATP 0.00003058 0.51862 23.8095
314 2VOH CIT 0.00289 0.45966 23.8095
315 2X7I CIT 0.003801 0.44107 23.8095
316 5IFS ADP 0.000225 0.40659 23.8095
317 4WZ6 ATP 0.00002166 0.57468 23.9521
318 1MR3 G3D 0.000000001803 0.56326 24.5509
319 3RLF ANP 0.0002491 0.45955 24.5509
320 2IYL GDP 0.00000253 0.59805 25.3521
321 2X77 GDP 0.000000001396 0.74687 25.3968
322 5GOE GDP 0.000000002844 0.72086 26.1905
323 3VMF GTP 0.000000001007 0.66746 26.1905
324 5L3V GDP 0.000002395 0.58301 26.1905
325 1Z6T ADP 0.0001822 0.48367 26.1905
326 5MZN ADP 0.0009919 0.48155 26.1905
327 2CHG ANP 0.0003345 0.47178 26.1905
328 4PJ3 ANP 0.002097 0.43996 26.1905
329 4OI4 ATP 0.001991 0.42202 26.1905
330 4KVA GTP 0.00002609 0.4124 26.1905
331 4U00 ADP 0.000001821 0.64682 26.3473
332 3CNL GNP 0.000000002377 0.76023 26.9461
333 4LJ9 ACP 0.00035 0.49227 28.5714
334 1D8C GLV 0.0266 0.41488 28.5714
335 1P7T PYR 0.03237 0.41219 28.5714
336 4FCW ADP 0.0001821 0.41155 28.5714
337 3KTA AP5 0.0002809 0.48021 29.3413
338 5DI3 GNP 0.000000000013 0.77241 29.9401
339 4M9Q GNP 0.00000000003618 0.75357 29.9401
340 5L3W GDP 0.00001032 0.5531 30.9524
341 5L3S GNP 0.00001576 0.50441 30.9524
342 2C9O ADP 0.0001445 0.47837 30.9524
343 2Q2Y ADP 0.0002431 0.47174 30.9524
344 2Q2Y MKR 0.0002542 0.46967 30.9524
345 5L3S G 0.03993 0.40081 30.9524
346 5KUT GDP 0.00000001015 0.53681 31.1377
347 1ZD9 GDP 0.0000000001487 0.74749 31.7365
348 3DOE GTP 0.00000000004565 0.73955 31.7365
349 1KSH GDP 0.00000000001461 0.69562 31.7365
350 2A5F GTP 0.0000000006037 0.68448 31.7365
351 3PCR GTP 0.0000000002955 0.70584 32.0988
352 1S9D GDP 0.000000007052 0.71295 32.3171
353 1RE0 GDP 0.0000000009837 0.54566 32.3171
354 4KAX GTP 0.00000000002764 0.6982 32.3353
355 1O3Y GTP 0.0000000001309 0.72053 32.5301
356 2J59 GTP 0.0000000001385 0.71951 32.5301
357 1J2J GTP 0.0000000001686 0.71596 32.5301
358 3N5C GDP 0.000000001158 0.76303 32.716
359 2W83 GTP 0.00000000007431 0.73075 32.7273
360 1FZQ GDP 0.0000000008514 0.76962 32.9341
361 4ZI2 GNP 0.00000000005151 0.74707 32.9341
362 4GOJ GNP 0.00000000003667 0.69372 32.9341
363 1YZG GDP 0.0000000009852 0.56912 32.9341
364 1WDT GTP 0.00000001413 0.66018 33.3333
365 4TTQ ATP 0.0001022 0.51868 33.3333
366 4PFO ADP 0.00008928 0.46949 33.3333
367 4V0K GDP 0.000000245 0.57813 33.5329
368 5KDO GDP 0.000001019 0.57142 33.7838
369 3T12 GDP ALF 0.000000003541 0.6692 34.7305
370 3T1O GDP 0.00000005134 0.53031 34.7305
371 5FG3 GDP 0.000000000259 0.55885 35.7143
372 3RC3 ANP 0.01293 0.41893 35.7143
373 4PU6 ASP 0.01689 0.41737 35.7143
374 2WMO GTP 0.0000000001046 0.78846 36.5269
375 4DID GDP 0.000000001204 0.74996 36.5269
376 4YC7 GNP 0.00000000005795 0.68769 36.5269
377 3W5J GDP 0.0000002003 0.68668 36.5269
378 4ITR GDP 0.00000001652 0.57416 36.5269
379 5KSP GDP 0.0000001028 0.65682 37.1257
380 5KSZ GCP 0.0000005261 0.61402 37.1257
381 1CS4 GSP 0.0000000008214 0.64677 38.0952
382 3PQC GDP 0.00000005345 0.66082 39.521
383 1R4A GNP 0.0000000000501 0.72855 40
384 1KK8 BEF ADP 0.000002273 0.56952 40.4762
385 1B7T ADP 0.00001145 0.55099 40.4762
386 3CV2 OXL 0.01609 0.42765 40.4762
387 2ZEJ GDP 0.0000003524 0.55525 41.9162
388 4YLG GDP 0.000000003003 0.69933 42.515
389 3B7G ANP 0.0001806 0.50033 42.8571
390 3Q85 GNP 0.00000000001581 0.85516 44.9102
391 1MKY GDP 0.00000000008053 0.58308 46.1078
392 3GJ7 GDP 0.00000000045 0.7833 47.3054
393 3GJ4 GDP 0.0000000004756 0.78212 47.3054
394 3GJ8 GDP 0.0000000007806 0.75905 47.3054
395 3GJ5 GDP 0.0000000009349 0.75527 47.3054
396 2W2X GSP 0.00000000006489 0.67476 47.3054
397 1XTQ GDP 0.0000000003391 0.66902 47.3054
398 3T5G GDP 0.0000000001951 0.60359 47.3054
399 1DS6 GDP 0.0000000001708 0.58023 47.3054
400 1DAR GDP 0.000000008006 0.72154 47.619
401 3ZQ6 ADP ALF 0.00004164 0.48473 47.619
402 2OZE AGS 0.000203 0.47666 47.619
403 1I4D GDP 0.0000000002953 0.80611 47.9042
404 5UWT GNP 0.000000000001074 0.79002 47.9042
405 5UWQ GNP 0.0000000000008393 0.77362 47.9042
406 5UWW GNP 0.000000000000876 0.77289 47.9042
407 5UWJ GNP 0.000000000000917 0.77213 47.9042
408 5UWU GNP 0.0000000000009267 0.77195 47.9042
409 5UWO GNP 0.0000000000009776 0.77113 47.9042
410 5UWI GNP 0.000000000001021 0.7704 47.9042
411 5UWR GNP 0.000000000001042 0.77001 47.9042
412 5DIF GNP 0.000000000001064 0.7697 47.9042
413 5UWH GNP 0.000000000001336 0.76595 47.9042
414 5DHF GNP 0.000000000001571 0.76327 47.9042
415 4HAT GNP 0.0000000000008935 0.75651 47.9042
416 5UWP GNP 0.000000000001111 0.75302 47.9042
417 3CH5 GDP 0.000000001267 0.74891 47.9042
418 5DI9 GNP 0.000000000001623 0.74701 47.9042
419 5UWS GNP 0.000000000001784 0.74567 47.9042
420 5UQW GDP 0.00000000003305 0.73592 47.9042
421 1HE1 GDP 0.000000007671 0.66324 47.9042
422 2FJU GSP 0.0000000001528 0.66142 47.9042
423 3GJ3 GDP 0.0000000004853 0.56896 47.9042
424 1HE1 AF3 0.00002861 0.56161 47.9042
425 5WDR GNP 0.000000000001176 0.76809 47.9532
426 1X1R GDP 0.0000000001457 0.6869 48.3146
427 3GJX GTP 0.000000000004235 0.76605 48.503
428 1E96 GTP 0.00000000001609 0.73933 48.503
429 5JCP GDP ALF 0.0000000004392 0.73697 48.503
430 3SBD GNP 0.00000000001865 0.73677 48.503
431 4XSH GSP 0.0000000003108 0.73335 48.503
432 5HPY GDP 0.0000000006104 0.73052 48.503
433 2WKQ GTP 0.0000000001012 0.72518 48.503
434 1MH1 GNP 0.00000000001723 0.7226 48.503
435 1WA5 GTP 0.000000000004978 0.68935 48.503
436 1G4U GDP 0.00000001984 0.65367 48.503
437 1G4U AF3 0.000254 0.51169 48.503
438 5TB5 GDP 0.00000000003081 0.81347 48.6486
439 5TAR GDP 0.00000000008566 0.78045 48.6486
440 3Q72 GNP 0.000000000003405 0.60434 48.7952
441 3M1I GTP 0.00000000000227 0.77695 49.1018
442 3WYF GTP 0.000000000003211 0.7743 49.1018
443 3WYG GTP 0.000000000002239 0.74215 49.1018
444 4XOI GTP 0.00000000004584 0.73012 49.1018
445 3LXR GDP 0.000000002094 0.72713 49.1018
446 1RYH GNP 0.00000000002246 0.63663 49.1018
447 4D0N GDP 0.0000000002935 0.56698 49.1018
448 2GCO GNP 0.0000000001814 0.63269 49.7006
449 2GCN GDP 0.000000003828 0.6173 49.7006
Pocket No.: 2; Query (leader) PDB : 2D7C; Ligand: GTP; Similar sites found: 14
This union binding pocket(no: 2) in the query (biounit: 2d7c.bio2) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4CS9 AMP 0.04257 0.40434 None
2 5CLO NS8 0.03209 0.40055 None
3 1V3S ATP 0.009917 0.40034 1.72414
4 4Z2S NDG 0.01923 0.41704 4.22535
5 4Z2S NAG 0.01923 0.41704 4.22535
6 2OFD NGA 0.02504 0.41136 4.92958
7 3KL3 GCU 0.02653 0.42009 5.98802
8 1ITU CIL 0.02982 0.40172 5.98802
9 3W9F I3P 0.04817 0.4043 6.58683
10 4TQK NAG 0.02033 0.41671 7.78443
11 4ME6 ADP 0.03077 0.40684 10.7784
12 3R7F CP 0.03146 0.40629 10.7784
13 1Y2W NAG 0.02564 0.41036 11.2676
14 5FJJ MAN 0.007044 0.41426 13.1737
Feedback