Receptor
PDB id Resolution Class Description Source Keywords
2EFC 2.09 Å NON-ENZYME: OTHER ARA7-GDP/ATVPS9A ARABIDOPSIS THALIANA GEF GTPASE VPS9 RAB5 NUCLEOTIDE TRANSPORT PROTEIN
Ref.: GDP-BOUND AND NUCLEOTIDE-FREE INTERMEDIATES OF THE NUCLEOTIDE EXCHANGE IN THE RAB5/VPS9 SYSTEM J.BIOL.CHEM. V. 285 36689 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP B:1200;
D:2200;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2EFE 2.08 Å NON-ENZYME: OTHER ARA7-GDPNH2/ATVPS9A ARABIDOPSIS THALIANA GEF GTPASE VPS9 RAB5 NUCLEOTIDE TRANSPORT PROTEIN
Ref.: GDP-BOUND AND NUCLEOTIDE-FREE INTERMEDIATES OF THE NUCLEOTIDE EXCHANGE IN THE RAB5/VPS9 SYSTEM J.BIOL.CHEM. V. 285 36689 2010
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 2EFE - GNH C10 H16 N6 O10 P2 c1nc2c(n1[....
2 4G01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 2EFH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 2EFE - GNH C10 H16 N6 O10 P2 c1nc2c(n1[....
2 4G01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 2EFH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 2EFE - GNH C10 H16 N6 O10 P2 c1nc2c(n1[....
2 4G01 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 2EFC - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 2EFH - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2EFE; Ligand: GNH; Similar sites found: 375
This union binding pocket(no: 1) in the query (biounit: 2efe.bio2) has 19 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4WOP CTP 0.001829 0.4093 1.77778
2 4AG5 ADP 0.000001207 0.62248 1.87266
3 2QG6 NMN 0.005174 0.42488 2.20994
4 1CR1 TTP 0.0006047 0.45714 2.62172
5 2C9O ADP 0.0001449 0.45141 2.62172
6 4KBF AMP 0.0003671 0.42981 2.62172
7 2B8T THM 0.002784 0.42908 2.69058
8 5I34 GDP 0.00002489 0.52484 2.76243
9 1G3M PCQ 0.0178 0.41132 2.76243
10 2PL3 ADP 0.00005737 0.5219 3.31492
11 2ZR9 DTP 0.00006266 0.51291 3.31492
12 1SQ5 ADP 0.00004677 0.51212 3.31492
13 3BOS CDP 0.0001382 0.45442 3.31492
14 2B8W ALF 5GP 0.002365 0.43587 3.31492
15 3BFV ADP 0.000005689 0.5625 3.37079
16 3FWY ADP 0.000008336 0.53566 3.37079
17 3DC4 ADP 0.00001174 0.47309 3.37079
18 2JLR ANP 0.0003106 0.46317 3.37079
19 2WHX ADP 0.00001107 0.46238 3.37079
20 1YXM ADE 0.01729 0.41907 3.37079
21 5GVR LMR 0.00004794 0.5501 3.4188
22 1YRB GDP 0.0000000004745 0.72067 3.43511
23 5LB3 ADP 0.00008428 0.51374 3.74532
24 4ZNL BEF ADP 0.0004824 0.46507 3.74532
25 2FAH GDP 0.001136 0.43823 3.74532
26 2C77 GNP 0.00000004658 0.64273 3.8674
27 2C78 GNP 0.00000002003 0.58686 3.8674
28 4H1V GNP 0.0000003623 0.5792 3.8674
29 3H86 AP5 0.0001725 0.5032 3.8674
30 1XMV ADP 0.0000895 0.47195 3.8674
31 1NN5 ANP 0.0006963 0.4701 3.8674
32 3DKP ADP 0.00009607 0.46068 3.8674
33 3DZD ADP 0.0004054 0.45805 3.8674
34 1NN5 2DT 0.03943 0.41192 3.8674
35 1T8U UAP SGN IDS SGN 0.01854 0.41144 3.8674
36 1XX6 ADP 0.001532 0.40955 3.8674
37 1T8U A3P 0.00684 0.40954 3.8674
38 2RGX AP5 0.001049 0.47425 3.8835
39 1OE0 TTP 0.006839 0.41777 3.91304
40 2CHG ANP 0.0003918 0.45001 3.9823
41 4RD0 GDP 0.000000007034 0.68309 4.11985
42 1YQT ADP 0.00000821 0.46562 4.11985
43 4FCW ADP 0.001237 0.42615 4.11985
44 4LJ9 ACP 0.002403 0.40684 4.11985
45 5L3W GDP 0.000002728 0.54573 4.41989
46 1G41 ADP 0.0001815 0.47899 4.41989
47 4R2I ANP 0.0005847 0.47896 4.41989
48 1JJV ATP 0.000007407 0.47554 4.41989
49 1U0J ADP 0.0003745 0.42866 4.41989
50 4GOX A3P 0.0005651 0.41853 4.41989
51 2GWH A3P 0.003545 0.40943 4.41989
52 5MEX SZZ 0.02133 0.4065 4.41989
53 5MEX PAP 0.008661 0.40306 4.41989
54 3IIJ ADP 0.00001164 0.49703 4.44444
55 1XP8 AGS 0.00005471 0.46495 4.49438
56 1FNN ADP 0.0001002 0.4648 4.49438
57 2I4I AMP 0.003429 0.41023 4.49438
58 1ION ADP 0.00003206 0.49884 4.52675
59 4QRH 0O2 0.007226 0.40846 4.7619
60 5WRJ A3P 0.002231 0.43703 4.86891
61 4LPS GDP 0.0000001268 0.63128 4.95868
62 1JI0 ATP 0.00000984 0.56798 4.97238
63 4PX9 ADP 0.00003268 0.53383 4.97238
64 2C04 GCP 0.000007452 0.5238 4.97238
65 1IWE IMP 0.0007557 0.51659 4.97238
66 3VX3 ADP 0.00001365 0.50175 4.97238
67 2Y65 ADP 0.00000359 0.46737 4.97238
68 1BG2 ADP 0.000001222 0.46688 4.97238
69 4TMK T5A 0.007014 0.4253 4.97238
70 1NST A3P 0.004809 0.41256 4.97238
71 1Z6T ADP 0.0002664 0.45649 5.07614
72 1T5C ADP 0.000002329 0.45696 5.24345
73 4IHQ ADP 0.0001233 0.44652 5.24345
74 3MWL 8OX 0.01799 0.40409 5.31401
75 3A1S GDP 0.00000004584 0.6518 5.42636
76 3KTA AP5 0.0004094 0.45786 5.49451
77 1GXU 2HP 0.0007085 0.45483 5.49451
78 3UIE ANP 0.00003277 0.49735 5.5
79 4DCT GDP 0.0000000006581 0.73736 5.52486
80 1JJ7 ADP 0.0000007671 0.64729 5.52486
81 2WIC GNP 0.0000005841 0.60049 5.52486
82 1FP6 ADP 0.00002306 0.51318 5.52486
83 5TSH ANP 0.00002674 0.48234 5.52486
84 3FB4 AP5 0.0007246 0.4798 5.52486
85 2IXE ATP 0.0005059 0.46271 5.52486
86 4IOK ADP 0.00127 0.45329 5.52486
87 5TSH ADP 0.00003134 0.45202 5.52486
88 4IOK XPO 0.001249 0.44859 5.52486
89 2D2F ADP 0.00002257 0.41712 5.52486
90 2Z5F A3P 0.005058 0.41547 5.52486
91 2PEZ DAT 0.000151 0.50294 5.58659
92 2DPY ADP 0.00009236 0.51918 5.61798
93 1G8S MET 0.01832 0.40617 5.65217
94 2ZE7 DST 0.01394 0.40338 5.92885
95 2ZE7 AMP 0.01297 0.40338 5.92885
96 1BO4 COA 0.007029 0.41526 5.95238
97 2XT3 ADP 0.0000006021 0.64477 5.99251
98 2W58 ADP 0.000003188 0.61071 6.07735
99 2OFW ADX 0.0001628 0.50991 6.07735
100 1R6B ADP 0.0003268 0.44878 6.07735
101 2J5V PCA 0.03779 0.40724 6.07735
102 1M7G ADX 0.0002695 0.48952 6.16114
103 1M7G AV2 0.0000108 0.48952 6.16114
104 1M7G ADP 0.0004404 0.47634 6.16114
105 1TQ4 GDP 0.000000002514 0.63557 6.36704
106 4PFO ADP 0.0002482 0.48268 6.36704
107 2BIF ANP 0.0008859 0.46801 6.36704
108 2BIF SIN 0.001482 0.46801 6.36704
109 2D7D ADP 0.0008414 0.42462 6.36704
110 4P32 ADP 0.0003498 0.46998 6.4257
111 2QN6 GDP 0.0000000005886 0.76558 6.45161
112 1F9V ADP 0.000001533 0.49274 6.62824
113 5FG3 GDP 0.00000000008833 0.68476 6.62983
114 3WXM GTP 0.00000009582 0.63997 6.62983
115 4P4T GDP 0.0000001572 0.58175 6.62983
116 2ZFI ADP 0.000002946 0.57611 6.62983
117 4NON GDP 0.00000002527 0.52832 6.62983
118 1IN4 ADP 0.0001076 0.48861 6.62983
119 3B7G ANP 0.0001905 0.4838 6.62983
120 3QKT ANP 0.0002465 0.48092 6.62983
121 5MZN ADP 0.0009116 0.46928 6.62983
122 1UJ2 ADP 0.0007248 0.46296 6.62983
123 4KFU ACP 0.0000133 0.46092 6.62983
124 1UJ2 C5P 0.0009581 0.45735 6.62983
125 2VF7 ADP 0.0001886 0.4571 6.62983
126 1SVI GDP 0.0000000002443 0.66707 6.66667
127 1JWY GDP 0.0000003413 0.59419 6.74157
128 1V8K ANP 0.00001387 0.54407 6.74157
129 1JWY ADP 0.00007788 0.50184 6.74157
130 1GHE ACO 0.0122 0.4031 6.77966
131 1OFH ADP 0.0003532 0.45433 6.89655
132 1K6M AGS 0.0005385 0.41183 7.11611
133 1WMA AB3 0.02693 0.40793 7.11611
134 1D8T GDP 0.000000000198 0.68747 7.18232
135 2BVN GNP 0.000000007789 0.66687 7.18232
136 1SVK ALF GDP 0.0000003508 0.62328 7.18232
137 1TAD GDP 0.0000004122 0.61781 7.18232
138 1BH2 GSP 0.000001039 0.59905 7.18232
139 1Y3A GDP 0.0000008083 0.59227 7.18232
140 2Q2Y ADP 0.0002941 0.49876 7.18232
141 2Q2Y MKR 0.000298 0.49723 7.18232
142 1CS4 GSP 0.0000005511 0.49614 7.18232
143 1AZT GSP 0.0000003284 0.49383 7.18232
144 1TAD ALF 0.0000004122 0.49368 7.18232
145 2ZPA ADP 0.00008323 0.49362 7.18232
146 2ODE ALF GDP 0.0000003804 0.48924 7.18232
147 1OS1 ATP 0.0003606 0.4804 7.18232
148 1S3G AP5 0.000705 0.48037 7.18232
149 1OS1 PYR 0.000457 0.47718 7.18232
150 5X40 ACP 0.0002779 0.47656 7.18232
151 4MKG AP5 0.0009341 0.47446 7.18232
152 1UKZ ADP 0.0009322 0.46696 7.18232
153 1B0U ATP 0.0002582 0.46673 7.18232
154 1RRC ADP 0.000005734 0.45706 7.18232
155 4A4Z ANP 0.001807 0.4434 7.18232
156 3EC1 GDP 0.000000003786 0.65352 7.49064
157 2NCD ADP 0.000004189 0.59312 7.49064
158 4HSE ADP 0.00007017 0.50394 7.49064
159 3P4X ADP 0.00002338 0.47604 7.49064
160 3RC3 ANP 0.005183 0.42631 7.49064
161 5L3R GCP 0.000004249 0.4845 7.50853
162 1LVG ADP 0.0000006551 0.5208 7.57576
163 3F81 STT 0.01624 0.40247 7.65027
164 3NHB ADP 0.000002138 0.60934 7.73481
165 1H65 GDP 0.0000015 0.57742 7.73481
166 3ZQ6 ADP ALF 0.00008338 0.50645 7.73481
167 1W0J ADP 0.00006378 0.49361 7.73481
168 4MKF AP5 0.001018 0.47379 7.73481
169 1W0J ADP BEF 0.001083 0.44364 7.73481
170 4IDN GNP 0.0009116 0.41214 7.73481
171 1ZUI SKM 0.0003262 0.49141 7.7381
172 2RCN GDP 0.00000000004349 0.71498 7.86517
173 1WF3 GNP 0.00000006054 0.65177 7.86517
174 2QEN ADP 0.00007687 0.49266 7.86517
175 2GJ8 ALF GDP 0.000000007956 0.55333 8.13953
176 2OG2 MLI 0.0000007242 0.64662 8.2397
177 3B9Q MLI 0.000002352 0.61747 8.2397
178 1AQU A3P 0.004198 0.41519 8.2397
179 1QF9 C5P 0.004873 0.4364 8.24742
180 2AWN ADP 0.000000107 0.70455 8.28729
181 3TK1 GDP 0.0000000001945 0.6521 8.28729
182 3MD0 GDP 0.000000003288 0.62694 8.28729
183 2IYL GDP 0.000001243 0.59394 8.4507
184 3E70 GDP 0.0000003428 0.57234 8.53659
185 1PUJ GNP 0.0000001146 0.61517 8.61423
186 4CVN ADP 0.00001356 0.56099 8.75912
187 1F2U ATP 0.0004073 0.47455 8.78378
188 2HCJ GDP 0.0000000001207 0.67876 8.83978
189 1KK1 GNP 0.000000002458 0.63413 8.83978
190 5H56 TYD 0.000208 0.49321 8.83978
191 5H56 ADP 0.000208 0.49321 8.83978
192 2FSH ANP 0.0008539 0.41466 8.83978
193 4TQK NAG 0.0122 0.41445 8.83978
194 1L2T ATP 0.0007118 0.40169 8.83978
195 5HR5 ADP 0.0004527 0.44648 8.98876
196 1D2N ANP 0.001742 0.40965 8.98876
197 2KIN ADP 0.000001031 0.46717 9
198 1NJF ADP 0.0000514 0.50301 9.2
199 1NJF AGS 0.0001018 0.4943 9.2
200 1GOJ ADP 0.0000001213 0.68797 9.3633
201 5L3V GDP 0.0000006397 0.59015 9.3633
202 5L3S GNP 0.000004132 0.48523 9.3633
203 4LC1 GDP 0.000000006382 0.70292 9.39227
204 1DAR GDP 0.000000005727 0.6349 9.39227
205 5I0H ADP BEF 0.0001575 0.4835 9.39227
206 3BFX A3P 0.002085 0.41173 9.39227
207 1KO8 6PG 0.0001386 0.48368 9.71429
208 1D2E GDP 0.0000000166 0.65231 9.73783
209 3FYH ADP 0.0004733 0.4081 9.73783
210 4OI4 ATP 0.001014 0.40472 9.73783
211 2GDJ ANP 0.0001468 0.4953 9.84848
212 5HCN GCP 0.0000000003691 0.74902 9.94475
213 4YMU ATP 0.00001785 0.54666 9.94475
214 2CE7 ADP 0.0001281 0.4723 9.94475
215 3A4M ADP 0.000002344 0.49794 10
216 3QF7 ANP 0.0001823 0.47834 10
217 3KJI ADP 0.00001974 0.51616 10.2362
218 2XAU ADP 0.00003277 0.49742 10.4869
219 2XTZ GSP 0.0000001176 0.63587 10.4972
220 2VVG ADP 0.0000001673 0.49303 10.4972
221 1G6O ADP 0.00008911 0.49299 10.4972
222 1P9B GDP 0.00008473 0.47858 10.4972
223 4D81 ADP 0.0003222 0.46246 10.4972
224 4ZG4 VO4 ADP 0.0001672 0.43046 10.4972
225 1W5T ANP 0.001044 0.41739 10.4972
226 1W5T ADP 0.002359 0.41687 10.4972
227 1G3Q ADP 0.00001934 0.52992 10.5485
228 3PQC GDP 0.00000004253 0.6435 10.7692
229 4PJ3 ANP 0.003085 0.419 10.8614
230 1B7T ADP 0.0001464 0.48321 10.8974
231 1G6H ADP 0.0000009022 0.64363 11.0497
232 4WZA ADP 0.000136 0.53393 11.0497
233 4WZA ACP 0.0001411 0.53313 11.0497
234 3BER AMP 0.001121 0.45328 11.0497
235 4ITM ATP 0.005065 0.42228 11.1111
236 2WJG GDP 0.00000008811 0.64865 11.1702
237 4M6T SAM 0.02166 0.40367 11.4754
238 3B5J 12D 0.00002391 0.54863 11.5226
239 1FQK GDP 0.0000004408 0.5335 11.5646
240 3AB3 GDP 0.0000002527 0.6096 11.6022
241 4R43 GDP 0.0002751 0.48232 11.6022
242 1IHU AF3 0.00002312 0.47244 11.6022
243 4U00 ADP 0.0000006518 0.46967 11.6022
244 1IHU ADP 0.00002598 0.4621 11.6022
245 4YS0 ADP 0.0007915 0.43686 11.6022
246 2BEK ATP 0.001031 0.41179 11.6022
247 1W7J ADP BEF 0.00008975 0.47602 11.6105
248 1X6V ADP 0.0001933 0.4004 11.6105
249 1FQJ GDP 0.0000002494 0.54126 11.9048
250 3IUY AMP 0.001617 0.41461 12.1547
251 1KK8 BEF ADP 0.00009618 0.47484 12.2302
252 2B4D COA 0.01092 0.40033 12.2807
253 4IEE AGS 0.0003834 0.4816 12.3596
254 3VM7 GLC 0.009901 0.42237 12.3596
255 2F3R G5P 0.007096 0.42383 12.5604
256 2WJH GDP 0.0000003049 0.57929 12.6506
257 2WJH FLC 0.00002377 0.50582 12.6506
258 5BQ5 ADP BEF 0.00006106 0.50043 12.6984
259 1SKQ GDP 0.000000007835 0.71067 12.7072
260 2XTN GTP 0.00000139 0.51206 12.7072
261 3CX8 GSP 0.0000002654 0.49702 12.7072
262 5GJC ATP 0.0001419 0.49601 12.7341
263 4GBM A3P 0.0009107 0.40965 12.7341
264 3BD9 A3P 0.008945 0.4061 12.7341
265 2HF9 GSP 0.00000007873 0.60667 12.8319
266 2V7Q ATP 0.00005834 0.50132 13.0137
267 2V7Q ADP 0.0003298 0.47857 13.0137
268 2CK3 ANP 0.0008814 0.42765 13.0137
269 2CK3 ADP 0.0009202 0.40644 13.0137
270 1NY5 ADP 0.0002491 0.4699 13.1086
271 2IS6 ADP 0.0002089 0.44727 13.2597
272 1YTM ATP 0.0003815 0.4357 13.2597
273 3TBK ANP 0.0002864 0.42428 13.2597
274 5CK5 GDP 0.0000000007472 0.65502 13.8122
275 3DEF GDP 0.0000008206 0.57732 13.8122
276 1VHT BA3 0.0000909 0.4926 13.8122
277 1QHH ATP 0.004562 0.41973 13.913
278 4QM7 GTP 0.00002856 0.47888 14.0351
279 4XTR ADP 0.00004786 0.48021 14.1243
280 4XTR ATP 0.0000567 0.45367 14.1243
281 4XVU ATP 0.00006181 0.45258 14.1243
282 3ZS9 ADP ALF 0.00007555 0.42984 14.1243
283 2WOJ ADP ALF 0.00007442 0.42902 14.1243
284 1XKV ATP 0.0000385 0.49401 14.3646
285 5N69 ADP 0.0001593 0.47601 14.6067
286 5M04 GDP 0.0000000004908 0.76944 14.9171
287 2VB6 ADP BEF 0.000192 0.42844 14.9171
288 3FVQ ATP 0.0004926 0.42842 14.9171
289 4FRZ ADP 0.000002174 0.48778 15.4696
290 3H4S ADP 0.000001084 0.48328 15.4696
291 4R98 GNH 0.000003505 0.57251 15.4982
292 4HI0 GDP 0.0000001505 0.57034 15.5779
293 1G7C 5GP 0.00000007824 0.65111 15.9574
294 3COB ADP 0.000000577 0.49293 16.0221
295 2WZF BGC 0.007279 0.42654 16.0221
296 2GK6 ADP 0.0004438 0.48497 16.4794
297 2OM2 GDP 0.0000006046 0.54761 16.6667
298 4BQS ADP 0.0000179 0.53881 17.0455
299 3ZFD ANP 0.00008013 0.48082 17.1271
300 5KDO GDP 0.000001077 0.53898 17.5676
301 1GOT GDP 0.0000005814 0.59609 17.8082
302 1GP2 GDP 0.0000006185 0.52766 18.3099
303 2ZPT A3P 0.02519 0.41554 19.1011
304 4B47 GDP 0.00000000008851 0.80578 19.337
305 1OYY AGS 0.008079 0.41238 19.337
306 3RLF ANP 0.0005015 0.41409 19.8895
307 5KSP GDP 0.00000007254 0.64254 20.442
308 5KSZ GCP 0.0000004826 0.5957 20.442
309 3W5J GDP 0.00001033 0.56838 20.9945
310 3ZIA ADP 0.000158 0.47617 21.547
311 3ZIA ATP 0.00008203 0.47387 21.547
312 4NCN GTP 0.000000005261 0.69202 22.0994
313 5KUT GDP 0.000000001971 0.66436 22.0994
314 4QOS ADP 0.0001938 0.47769 22.0994
315 1YZG GDP 0.000000002216 0.66283 22.905
316 1NRJ GTP 0.00000004386 0.64391 23.8532
317 2QTV GNP 0.00000004793 0.65109 23.9521
318 1ZJ6 G3D 0.000000002255 0.71253 24.8619
319 1MKY GDP 0.000000000234 0.68587 24.8619
320 1M2O GNP 0.00000003619 0.65945 24.8619
321 4TTQ ATP 0.0001201 0.45848 26.0465
322 1FZQ GDP 0.0000000003349 0.67943 27.0718
323 1OXV ANP 0.00001689 0.47758 27.6243
324 4HUT ATP 0.00741 0.42036 27.6243
325 4M9Q GNP 0.00000000265 0.6197 28.7293
326 2QZ4 ADP 0.0001136 0.47489 28.7293
327 1KSH GDP 0.0000000008369 0.72148 29.2818
328 1UPT GTP 0.000000006302 0.68525 30.4094
329 4BAS GNP 0.0000002865 0.61004 31.1558
330 4V0K GDP 0.00000002662 0.55674 32.5444
331 1R4A GNP 0.000000001272 0.72337 32.7273
332 1J2J GTP 0.00000001295 0.58353 33.7349
333 1O3Y GTP 0.00000002415 0.57516 33.7349
334 2FH5 GTP 0.00000000008274 0.69235 34.2541
335 1S9D GDP 0.000000002245 0.71261 34.7561
336 1RE0 GDP 0.0000000003536 0.66344 34.7561
337 1F6B GDP 0.00000002657 0.61979 35.9116
338 2A5F GTP 0.00000003299 0.65853 36
339 2ZEJ GDP 0.00000005565 0.65347 37.5691
340 1GWN GTP 0.00000002078 0.65855 38.1215
341 1M7B GTP 0.00000001399 0.60849 38.1215
342 4WZ6 ATP 0.00001432 0.56595 38.674
343 1G7S GDP 0.00000000168 0.71847 39.2265
344 1ZD9 GDP 0.0000000009081 0.67168 40.884
345 1MR3 G3D 0.000000000637 0.68478 41.4365
346 3REF GDP 0.00000002023 0.58607 41.9889
347 2WKQ GTP 0.000000003776 0.60104 43.0939
348 4DID GDP 0.0000000009122 0.73077 43.6464
349 2NGR GDP 0.000000000385 0.69407 43.6464
350 1GRN GDP 0.000000001253 0.68212 43.6464
351 4ITR GDP 0.0000000074 0.67531 43.6464
352 3T1O GDP 0.0000003834 0.58257 43.6464
353 1E96 GTP 0.000000006128 0.5703 43.6464
354 3T12 GDP ALF 0.0000005602 0.53642 43.6464
355 1I4D GDP 0.00000000005598 0.81549 44.1989
356 1A4R GDP 0.0000000022 0.69893 44.1989
357 1A4R GNH 0.000000003864 0.68425 44.1989
358 3SBD GNP 0.000000002951 0.5813 44.1989
359 1G4U GDP 0.000000007046 0.6346 44.7514
360 1MH1 GNP 0.000000005912 0.55903 44.7514
361 2FJU GSP 0.000000003346 0.69433 44.9438
362 3T5G GDP 0.00000000002243 0.76184 45.3039
363 1RYH GNP 0.00000000144 0.68513 45.3039
364 1HE1 GDP 0.000000001979 0.64038 45.4545
365 1NF3 GNP 0.00000003 0.54929 45.8564
366 1XTQ GDP 0.0000000002175 0.75514 46.3277
367 2J0V GDP 0.00000000009722 0.71759 46.4088
368 1DS6 GDP 0.00000000005628 0.71046 46.4088
369 2W2X GSP 0.000000003098 0.69583 48.0663
370 3Q85 GNP 0.00000000002561 0.72279 48.5207
371 1KMQ GNP 0.00000001636 0.66954 48.6188
372 4U5X GNP 0.00000000875 0.67204 48.8764
373 1OW3 GDP 0.000000004405 0.68172 49.1713
374 5HPY GDP 0.000000005996 0.67575 49.1713
375 2G77 GDP 0.0000000003638 0.70565 49.7238
Pocket No.: 2; Query (leader) PDB : 2EFE; Ligand: GNH; Similar sites found: 13
This union binding pocket(no: 2) in the query (biounit: 2efe.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5AHO TLA 0.004325 0.43045 2.76243
2 5CDH TLA 0.04364 0.40208 3.8674
3 4NMC FAD 0.02136 0.40134 4.41989
4 1VBO MAN MAN MAN 0.02961 0.40175 4.69799
5 5WRI A3P 0.003468 0.40139 4.86891
6 1X9I G6Q 0.002588 0.43544 5.24345
7 3QXC ATP 0.0009448 0.40129 6.07735
8 3E9I XAH 0.01387 0.40104 8.61423
9 4ADC PLP 0.01152 0.40487 12.7072
10 4TO8 FLC 0.01163 0.41683 13.8122
11 4Q4K FMN 0.01038 0.40261 15.4696
12 1HE1 AF3 0.02929 0.40058 45.4545
13 2G77 AF3 0.02342 0.40598 49.7238
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