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Receptor
PDB id Resolution Class Description Source Keywords
2FLI 1.8 Å EC: 5.1.3.- THE CRYSTAL STRUCTURE OF D-RIBULOSE 5-PHOSPHATE 3-EPIMERASE FROM STREPTOCOCUS PYOGENES COMPLEXED WITH D-XYLITOL 5- P HOSPHATE STREPTOCOCCUS PYOGENES D-RIBULOSE 5-PHOSPHATE 3-EPIMERASE (BETA/ALPHA)8-BARREL D-XYLITOL 5-PHOSPHATE ISOMERASE
Ref.: D-RIBULOSE 5-PHOSPHATE 3-EPIMERASE: FUNCTIONAL AND STRUCTURAL RELATIONSHIPS TO MEMBERS OF THE RIBULOSE-PHOSPHATE BINDING (BETA/ALPHA)(8)-BARREL SUPERFAMILY(,). BIOCHEMISTRY V. 45 2493 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DX5 A:1901;
B:1902;
C:1903;
D:1904;
E:1905;
F:1906;
G:1911;
H:1912;
I:1913;
J:1914;
K:1915;
L:1916;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
232.126 C5 H13 O8 P C([C@...
ZN A:1981;
B:1982;
C:1983;
D:1984;
E:1985;
F:1986;
G:1991;
H:1992;
I:1993;
J:1994;
K:1995;
L:1996;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2FLI 1.8 Å EC: 5.1.3.- THE CRYSTAL STRUCTURE OF D-RIBULOSE 5-PHOSPHATE 3-EPIMERASE FROM STREPTOCOCUS PYOGENES COMPLEXED WITH D-XYLITOL 5- P HOSPHATE STREPTOCOCCUS PYOGENES D-RIBULOSE 5-PHOSPHATE 3-EPIMERASE (BETA/ALPHA)8-BARREL D-XYLITOL 5-PHOSPHATE ISOMERASE
Ref.: D-RIBULOSE 5-PHOSPHATE 3-EPIMERASE: FUNCTIONAL AND STRUCTURAL RELATIONSHIPS TO MEMBERS OF THE RIBULOSE-PHOSPHATE BINDING (BETA/ALPHA)(8)-BARREL SUPERFAMILY(,). BIOCHEMISTRY V. 45 2493 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 2FLI - DX5 C5 H13 O8 P C([C@@H]([....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 7 families.
1 2FLI - DX5 C5 H13 O8 P C([C@@H]([....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3OVQ - 5RP C5 H11 O8 P C([C@H]([C....
2 3OVR - 5SP C5 H11 O8 P C([C@H]([C....
3 2FLI - DX5 C5 H13 O8 P C([C@@H]([....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DX5; Similar ligands found: 49
No: Ligand ECFP6 Tc MDL keys Tc
1 DX5 1 1
2 LXP 1 1
3 A5P 1 1
4 FQ8 0.794118 0.971429
5 S6P 0.71875 0.970588
6 M2P 0.666667 0.914286
7 GOS 0.666667 0.914286
8 DG6 0.628571 0.971429
9 LX1 0.588235 0.861111
10 M6R 0.552632 0.785714
11 AGP 0.552632 0.785714
12 HG3 0.548387 0.828571
13 R5P 0.540541 0.861111
14 TX4 0.540541 0.659574
15 R52 0.540541 0.861111
16 PA5 0.526316 0.837838
17 R10 0.526316 0.837838
18 G6Q 0.512821 0.861111
19 52L 0.511628 0.680851
20 F6R 0.5 0.916667
21 6PG 0.5 0.837838
22 LG6 0.5 0.837838
23 TG6 0.5 0.916667
24 1GP 0.484848 0.911765
25 G3P 0.484848 0.911765
26 P6T 0.47619 0.888889
27 2FP 0.47619 0.888889
28 P6F 0.47619 0.888889
29 I22 0.47619 0.916667
30 PAN 0.47619 0.632653
31 E4P 0.472222 0.805556
32 KD0 0.465116 0.837838
33 9C2 0.465116 0.62
34 5SP 0.45 0.944444
35 5RP 0.45 0.944444
36 HMS 0.45 0.944444
37 DEZ 0.447368 0.837838
38 DER 0.447368 0.837838
39 H4P 0.444444 0.767442
40 DXP 0.435897 0.763158
41 1NT 0.428571 0.837838
42 RB0 0.428571 0.647059
43 XYL 0.428571 0.647059
44 4TP 0.425 0.704545
45 LRY 0.416667 0.673913
46 PAI 0.408163 0.711111
47 RES 0.404762 0.632653
48 XBP 0.404762 0.888889
49 RUB 0.404762 0.888889
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 282
This union binding pocket(no: 1) in the query (biounit: 2fli.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1GXU 2HP None
2 3LLZ GAL NGA None
3 2W47 UNF None
4 2BS5 BGC GAL FUC None
5 1OFS SUC None
6 1ZEI CRS None
7 6BKL EU7 None
8 2BQP GLC None
9 1FIW PBZ 0.909091
10 4OCT AKG 1.36364
11 1YXM ADE 1.36364
12 4BI7 PGA 1.81818
13 2VEG PMM 1.81818
14 2D24 XYS XYS 1.81818
15 3AI3 SOE 1.81818
16 1OVD ORO 2.27273
17 1OVD FMN 2.27273
18 4ORM ORO 2.27273
19 4ORM FMN 2.27273
20 4ORM 2V6 2.27273
21 1TV5 FMN 2.27273
22 4IP7 FLC 2.27273
23 2YPI PGA 2.27273
24 4YMZ 13P 2.27273
25 5FYR INS 2.27273
26 2HJR CIT 2.27273
27 2Q8Z NUP 2.72727
28 1TRD PGH 2.72727
29 4AF0 IMP 2.72727
30 3TAO PGH 2.72727
31 3GLC R5P 2.72727
32 1TB3 FMN 2.72727
33 3K0T BGC 2.7972
34 2VQ5 HBA 2.98507
35 1SW0 PGA 3.18182
36 4Z87 5GP 3.18182
37 2Q3O FMN 3.18182
38 5EO8 TFU 3.18182
39 4Z0G 5GP 3.18182
40 5CSS G3P 3.18182
41 1Z4O GL1 3.18182
42 5EYW PGA 3.18182
43 4K37 SAM 3.18182
44 4CCN OGA 3.18182
45 5VSM MET 3.18182
46 2RJH DCS 3.18182
47 2BTM PGA 3.18182
48 3LXI CAM 3.18182
49 1YNQ NDP 3.18182
50 4XP7 FNR 3.18182
51 6BVE PGA 3.18182
52 1RBL CAP 3.18182
53 1NB9 ADP 3.40136
54 1NB9 RBF 3.40136
55 5YRM BGC GLC 3.52113
56 5YRJ BGC GLC 3.52113
57 2OEM 1AE 3.63636
58 3VKC FPQ 3.63636
59 1SR9 KIV 3.63636
60 3UWV 2PG 3.63636
61 3JQQ A2P 3.63636
62 4QDF 30Q 3.63636
63 1LYX PGA 3.63636
64 1PS9 FMN 3.63636
65 4JIQ 1L5 3.63636
66 4JIQ FMN 3.63636
67 2X0K PPV 3.63636
68 1W3T 3GR 3.63636
69 1VHN FMN 3.63636
70 2R14 FMN 3.63636
71 2R14 TXD 3.63636
72 2Q3R FMN 3.63636
73 2PZE ATP 3.63636
74 1ZTH ADP 3.63636
75 3O94 NCA 3.79147
76 3AXK NDP 3.87597
77 4DOO DAO 3.90244
78 1UI0 URA 3.90244
79 1WDD CAP 3.90625
80 6FOF LAT 4.08163
81 1CX9 NHP 4.09091
82 2Y88 2ER 4.09091
83 4NAE 1GP 4.09091
84 2Z6I FMN 4.09091
85 4EWN 0VR 4.09091
86 1GVF PGH 4.09091
87 5AHN IMP 4.09091
88 1OX5 1PR 4.09091
89 4IGH FMN 4.09091
90 4IGH ORO 4.09091
91 4IGH 1EA 4.09091
92 5AHM IMP 4.09091
93 1UJP CIT 4.09091
94 1GPJ CIT 4.09091
95 2ZRU FMN 4.09091
96 3ZGJ RMN 4.09091
97 2RDT 2RD 4.09091
98 2RDT FMN 4.09091
99 5DRB 5FJ 4.09091
100 1P4V GLY 4.09091
101 5LXB 7A9 4.09091
102 1Q6O LG6 4.16667
103 6D5V FVY 4.19162
104 1WQ1 AF3 4.21687
105 4DD8 BAT 4.32692
106 1KBJ FMN 4.54545
107 1G51 AMP 4.54545
108 4CW5 FMN 4.54545
109 1KC7 PPR 4.54545
110 2PNC CLU 4.54545
111 4TO8 FLC 4.54545
112 6BU0 IHP 4.58015
113 5CIC 51R 4.62963
114 2X1L ADN 4.77099
115 1VKF CIT 4.78723
116 3B0P FMN 5
117 3C3N FMN 5
118 2V63 CAP 5
119 1MO9 KPC 5
120 1MO9 FAD 5
121 2VDH CAP 5
122 2V6A CAP 5
123 2V68 CAP 5
124 2V67 CAP 5
125 1UZH CAP 5
126 4JGX PLM 5.42636
127 1PVN MZP 5.45455
128 1OFD FMN 5.45455
129 1OFD AKG 5.45455
130 3KRU FMN 5.45455
131 1GTE FMN 5.45455
132 1GTE IUR 5.45455
133 4YJK URA 5.45455
134 3W9Z FMN 5.45455
135 1AL8 DHP 5.45455
136 1AL8 FMN 5.45455
137 5VJE GOS 5.45455
138 5N9Z CAP 5.7554
139 4WCX MET 5.90909
140 3GAY P6T 5.90909
141 1ZQ5 E04 5.90909
142 1ZQ5 NAP 5.90909
143 1FQJ ALF 5.90909
144 4KCT PYR 5.90909
145 1TZJ A3B 5.90909
146 3HDY FAD 5.90909
147 4RJD TFP 6.06061
148 1C3M MAN MAN 6.12245
149 1UUO FMN 6.36364
150 1UUO BRF 6.36364
151 1UUO ORO 6.36364
152 5WS9 ATP 6.36364
153 1AJ8 CIT 6.36364
154 5WS9 OXL 6.36364
155 5GLT BGC GAL NAG GAL 6.69014
156 1UZD CAP 6.71642
157 5B09 4MX 6.73077
158 2QIE 8CS 6.75676
159 2GJN NIS 6.81818
160 2GJN FMN 6.81818
161 1QDS PGA 6.81818
162 4HKP TKW 6.81818
163 4HKP 16B 6.81818
164 5CAD PCA 6.81818
165 1OYB HBA 6.81818
166 4A3U FMN 6.81818
167 4YZC STU 6.81818
168 1OYB FMN 6.81818
169 1IR2 CAP 7.14286
170 1ONI BEZ 7.24638
171 3QH2 3NM 7.27273
172 4Q4K FMN 7.27273
173 1Y7P RIP 7.27273
174 2F5X ASP 7.27273
175 3HQ9 OXL 7.27273
176 1UTJ ABN 7.27273
177 1ZGS XMM 7.27273
178 2GN3 MMA 7.27273
179 5XEG AKG 7.27273
180 5NUE NAD 7.27273
181 2GN3 MAN 7.27273
182 4NS0 PIO 7.5188
183 3MJY IJZ 7.72727
184 6BKA FMN 7.72727
185 3MI2 PFU 7.72727
186 3MJY FMN 7.72727
187 2FJK 13P 7.72727
188 1FDJ 13P 7.72727
189 3HF3 FMN 7.73639
190 4JX1 CAH 7.9646
191 3EXS 5RP 8.18182
192 4TQK NAG 8.18182
193 4M5P FMN 8.18182
194 4JCA CIT 8.18182
195 1PZ1 NAP 8.18182
196 3BW2 FMN 8.63636
197 2QCD U5P 8.63636
198 2F6U CIT 8.63636
199 1NJJ ORX 8.63636
200 3KDN CAP 8.63636
201 3DUV KDO 8.63636
202 6EK3 OUL 9.09091
203 5I8F ML1 9.09091
204 4A22 TD4 9.09091
205 2P3V SRT 9.09091
206 1EIX BMQ 9.09091
207 5EXK MET 9.09091
208 2NVA PL2 9.09091
209 1P0Z FLC 9.16031
210 1LRH NLA 9.20245
211 2TPS TPS 9.54545
212 4YRD 3IT 9.54545
213 1WB4 SXX 9.54545
214 2VD9 IN5 9.54545
215 4UTW RFW 9.60699
216 4UTU LRY 9.60699
217 5XFV FMN 10
218 4WZH FMN 10
219 1ICP FMN 10
220 3N9R TD3 10
221 3C56 PH4 10
222 3ATY FMN 10
223 5A5W GUO 10.4545
224 1TUF AZ1 10.4545
225 5GVH FMN 10.9091
226 3U6W KIV 10.9091
227 2OO0 PLP 10.9091
228 5OCS FMN 10.9091
229 1VYP TNF 10.9091
230 1VYP FMN 10.9091
231 2Z6J FMN 11.3636
232 1LBF 137 11.3636
233 4V15 PLP 11.3636
234 1UDY FAD 11.3636
235 1UDY CS8 11.3636
236 2HYR BGC GLC 11.4754
237 2GUC MAN 11.4754
238 2GUD MAN 11.4754
239 1L5Y BEF 11.6129
240 2BDG PBZ 11.6592
241 5TPV TYD 11.7647
242 2PLK P3D 11.8182
243 5LXT GTP 11.8182
244 4QNW FMN 11.8182
245 1ME8 RVP 12.2727
246 4I9A NCN 12.2727
247 5AHO TLA 12.2727
248 4JEJ 1GP 12.7273
249 1DQX BMP 12.7273
250 1KBI PYR 12.7273
251 1KBI FMN 12.7273
252 5J5R IMP 13.1818
253 5J5R 6G1 13.1818
254 2HSA FMN 13.1818
255 2BLE 5GP 13.1818
256 4ZX2 4TE 13.1818
257 2FFC U5P 13.6364
258 3OIX FMN 13.6364
259 4QCK ASD 14.5455
260 5TCI MLI 15
261 1F76 FMN 15
262 2FKA BEF 15.5039
263 5GJO PLP 15.9091
264 1JCM 137 15.9091
265 2XRH NIO 16
266 1QO8 FAD 16.3636
267 1Z44 FMN 16.8182
268 1Z42 FMN 16.8182
269 1Z48 FMN 16.8182
270 4LUT DCS 16.8182
271 1Z41 FMN 16.8182
272 2C6Q NDP 17.7273
273 2C6Q IMP 17.7273
274 1EP2 ORO 19.5455
275 1EP2 FMN 19.5455
276 5TQZ GLC 20
277 4IXH IMP 20.4545
278 4RYV ZEA 21.9355
279 1M5W DXP 23.6364
280 1DBT U5P 23.6364
281 1X1Z BMP 31.3636
282 1LOR BMP 31.3636
Pocket No.: 2; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 44
This union binding pocket(no: 2) in the query (biounit: 2fli.bio2) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 3NW7 LGV 2.72727
2 6AM8 TRP 2.72727
3 5T96 79J 3.18182
4 5VSM 5AD 3.18182
5 4CCK OGA 3.18182
6 3HQP OXL 3.63636
7 3RNM FAD 3.63636
8 5NE2 DGL 4.09091
9 2AOU CQA 4.09091
10 4WVW SLT 4.16667
11 5V6F MAN BMA MAN 4.34783
12 3VV1 GAL FUC 4.375
13 6F5W KG1 4.54545
14 1UA4 GLC 4.54545
15 1UA4 BGC 4.54545
16 3KVY URA 5
17 5C9P FUC 5
18 5EYP GTP 5.32544
19 3RYC GTP 5.59441
20 5OYA CAP 5.7554
21 1LES GLC FRU 5.76923
22 5NCB JZ3 5.90909
23 5YJS SAL 5.90909
24 5O0J GLC 5.90909
25 3HDY GDU 5.90909
26 4D4U FUC NDG GAL FUC 6.36364
27 5KBF CMP 6.36364
28 5OO5 UUA 6.45161
29 1UKG MMA 7.27273
30 4TXE 38F 7.27273
31 3WQD PLP 999 7.72727
32 1W8S FBP 8.18182
33 1I7E IBS 9.09091
34 2NLI LAC 9.09091
35 2NLI FMN 9.09091
36 1BWV CAP 9.42029
37 4PB2 5UD 10
38 3OID TCL 10.8527
39 2CBO TH2 11.3043
40 5O4J PJL 12.4088
41 5O4J SAH 12.4088
42 1L7N ALF 15.6398
43 1IGW PYR 19.5455
44 4CNK MEU 23.1818
Pocket No.: 3; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 51
This union binding pocket(no: 3) in the query (biounit: 2fli.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 4BHL ARG 1.36364
2 2HFU MEV 2.27273
3 2GOU FMN 2.72727
4 1BC5 ACE ASN TRP GLU THR PHE 2.72727
5 3ROE THM 3.18182
6 4YSW URC 3.18182
7 2YGM GLA NAG GAL FUC 3.18182
8 5YRL GLC GLC 3.52113
9 5YRG BGC GLC 3.52113
10 5YRI GLC GLC 3.52113
11 2H8Z 8CM 4.09091
12 2H8Z FMN 4.09091
13 3IP6 PRO 4.54545
14 1ZOS MTM 4.54545
15 6FP4 E1T 4.54545
16 6FP4 FAD 4.54545
17 3QFA FAD 4.54545
18 4B6C B5U 4.59184
19 1TVP CBI 5
20 6GNO XDI 5.18518
21 2ZQO NGA 5.38462
22 3ESS 18N 5.45455
23 5N6C TLA 5.45455
24 6F6D AKG 5.45455
25 2G50 PYR 5.45455
26 1FQK ALF 5.90909
27 5KEW 6SB 6.25
28 4N7C AEF 6.25
29 4M00 SUC 6.36364
30 2FMD MAN MAN 6.36364
31 3GD4 FAD 6.81818
32 1J6X MET 6.81818
33 1O5Q PYR 7.27273
34 1FDJ 2FP 7.72727
35 1QPR PPC 8.63636
36 5K8S CMP 9.45946
37 3R7F CP 9.54545
38 1EYE PMM 9.54545
39 4YSX FAD 10
40 4ZNO SUC 10.9091
41 1IS3 LAT 11.1111
42 2HYQ MAN MAN 11.4754
43 2NU5 NAG 11.4754
44 2NUO BGC 11.4754
45 5ITZ GTP 11.811
46 2XMY CDK 11.8182
47 4PTN GXV 11.8182
48 4JLS 3ZE 14.4737
49 1EX7 5GP 18.2796
50 4JWX 1N4 18.6364
51 3FIU POP 21.8182
Pocket No.: 4; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 39
This union binding pocket(no: 4) in the query (biounit: 2fli.bio2) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 2P7Q GG6 None
2 1B4B ARG 1.40845
3 2OFD NGA 1.40845
4 1RM8 BAT 2.36686
5 3GD8 GOL 2.72727
6 4CCO OGA 3.18182
7 5D6T NGA 3.18182
8 4Y3O OGA 3.18182
9 3L6C MLI 3.18182
10 4Y9J UCC 3.63636
11 1JJ7 ADP 3.63636
12 4Y9J FAD 3.63636
13 3O84 HTJ 3.63636
14 3SSO SAH 4.09091
15 5F90 GLA GAL BGC 5VQ 5.12821
16 5G5G MCN 5.90909
17 3S6X SIA GAL BGC 6.36364
18 4YKG NAD 6.81818
19 1G6H ADP 7.27273
20 1ZFJ IMP 7.72727
21 4OKE AMP 8.33333
22 5WBF LAC 9.54545
23 2OQ5 BEN 10
24 3FC4 EDO 10
25 1DJX I3P 10
26 5N0L ILE 10.6918
27 3WIR BGC 10.9091
28 6ARJ BW4 11.3636
29 6ARJ SAH 11.3636
30 3AJ6 NGA 12.2727
31 3W8X FTK 12.7273
32 3W8X FAD 12.7273
33 3OCP CMP 13.6691
34 4LAE NAP 13.7725
35 4LAE 1VM 13.7725
36 5Y6Q MCN 16.0494
37 3OQJ 3CX 16.8182
38 1DTL BEP 22.9814
39 3QDV A2G 26.5734
Pocket No.: 5; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 51
This union binding pocket(no: 5) in the query (biounit: 2fli.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1V1A KDG 2.27273
2 1V1A ADP 2.27273
3 4JGT PYR 2.27273
4 1S8G DAO 2.47934
5 3GM5 CIT 2.51572
6 4COQ SAN 2.72727
7 3P4X ADP 2.72727
8 1K3A ACP 2.72727
9 2F9W PAU 2.72727
10 2IBN I1N 2.72727
11 1MFA GLA MMA ABE 3.14961
12 4K39 SAM 3.18182
13 4Y4V DAL 3.18182
14 4BWL MN9 3.63636
15 1SDW IYT 3.63636
16 1OGD RIP 3.81679
17 4IF4 BEF 3.84615
18 5GZK BGC 4.09091
19 4K91 SIN 4.09091
20 4M26 AKG 4.09091
21 3QMN A3P 4.65116
22 2UVO NAG 4.67836
23 3BEO UDP 5
24 5MU6 MYA 5
25 5MU6 KFK 5
26 6CQF F97 5
27 2JK0 ASP 5.45455
28 5O9W AKG 5.90909
29 1C1X HFA 6.36364
30 5TFZ 7BC 6.36364
31 1BW9 PPY 6.36364
32 5ENZ UDP 6.36364
33 2ZUX RAM 6.36364
34 3VHH VHH 6.50407
35 6BND OPE 6.81818
36 3P3N AKG 7.27273
37 1SJD NPG 7.27273
38 1H2K OGA 7.27273
39 4B7E OGA 7.27273
40 2XUM OGA 7.27273
41 6B74 BEN 7.72727
42 4UP4 GAL NAG 8.18182
43 1WPQ 13P 8.63636
44 5X8G S0N 9.09091
45 1IR1 CAP 10.5691
46 2O66 FLC 11.1111
47 1U1J MET 15.9091
48 5JSP DQY 15.9091
49 3FGZ BEF 16.4062
50 1VBH PEP 22.7273
51 3UB7 ACM 23.2044
Pocket No.: 6; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 27
This union binding pocket(no: 6) in the query (biounit: 2fli.bio2) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1WUW TSU None
2 2AJ4 GLA 2.72727
3 4PU6 ASP 3.05344
4 4K38 SAM 3.18182
5 5JY4 ISC 3.18182
6 6G47 SIA 3.34928
7 4AZC NGW 3.63636
8 3VY6 BGC BGC 4.25532
9 5W0N UPU 4.54545
10 5KAX RHQ 4.81928
11 5NDB 8TW 5.2
12 3MPB FRU 5.90909
13 1PIE GLA 6.81818
14 5JWP AKG 7.27273
15 1H2M OGA 7.27273
16 6HDT BTN 7.5188
17 5V3D FCN 7.58621
18 3EW2 BTN 8.14815
19 5X7Q GLC GLC 8.18182
20 3GDN FAD 8.18182
21 3GDN HBX 8.18182
22 5XNC N4P 8.63636
23 3P7I P7I 9.09091
24 3MAN BMA BMA MAN 9.09091
25 2GOO NDG 13.1579
26 2WHL MAN BMA BMA 14.0909
27 4Z1D PEP 15
Pocket No.: 7; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 15
This union binding pocket(no: 7) in the query (biounit: 2fli.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 1UGY GLA BGC None
2 5CGE 51F 3.18182
3 5A89 ADP 3.20513
4 5A89 FMN 3.20513
5 6CI9 F3V 3.63636
6 2UVO NDG 4.67836
7 5NUF NAD 7.27273
8 4XZ3 ACP 7.27273
9 3K8D KDO 7.72727
10 2VD9 EPC 9.54545
11 3UN3 G16 10.4545
12 3ZIA ADP 12.2727
13 4OHB 5HM 12.6316
14 2GNK ATP 13.3929
15 2OOR NAD 15.4545
Pocket No.: 8; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 6
This union binding pocket(no: 8) in the query (biounit: 2fli.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 2Q4W FAD 2.72727
2 5DEQ ARA 2.72727
3 4DC2 ADE 3.63636
4 3RGA LSB 4.09091
5 2VHA GLU 4.52962
6 1LVL FAD 13.1818
Pocket No.: 9; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 28
This union binding pocket(no: 9) in the query (biounit: 2fli.bio1) has 21 residues
No: Leader PDB Ligand Sequence Similarity
1 1XXA ARG None
2 4CUB GAL NAG 1.63934
3 3HPY MCT 1.81818
4 1P1C SAH 2.51256
5 2VZ6 FEF 2.72727
6 1GPM CIT 2.72727
7 1VGR COA 3.18182
8 4TMC HBA 3.63636
9 4PLT OXM 3.63636
10 4PLT NAI 3.63636
11 4WZA ACP 4.09091
12 4WZA ADP 4.09091
13 6D5L FW7 4.19162
14 4AT0 FAD 4.54545
15 5E9G GLV 4.54545
16 4JNA FAD 5
17 3HDY FDA 5.90909
18 6DEF GCP 5.90909
19 3D9F FAD 5.90909
20 3D9F N6C 5.90909
21 4YKG FAD 6.81818
22 2GNB MAN 7.27273
23 1GV0 NAD 7.27273
24 4AZP A9M 7.97101
25 3AB1 FAD 8.18182
26 3E8T UQ8 8.63636
27 4LNU GTP 9.46746
28 5E9W SAH 21.8182
Pocket No.: 10; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 1
This union binding pocket(no: 10) in the query (biounit: 2fli.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 3WUC GLC GAL 3.64964
Pocket No.: 11; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 27
This union binding pocket(no: 11) in the query (biounit: 2fli.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
1 3BZ3 YAM 1.81818
2 1UXG FUM 2.27273
3 1UXG NAD 2.27273
4 4NZ6 DGL 2.27273
5 5DQY BEZ 2.85714
6 3LZW NAP 3.18182
7 4TWL ASC 3.18182
8 3LZW FAD 3.18182
9 4TMC FMN 3.63636
10 4UTG ANP 4.91329
11 2C91 NAP 5
12 5U8U FAD 5
13 4N02 FNR 5
14 1GK8 CAP 5
15 3AYI HCI 5
16 3AYI FAD 5
17 2Y5S 78H 5.45455
18 2GZ3 NAP 5.45455
19 1GPE FAD 5.45455
20 3UBM COA 6.36364
21 4WOP CTP 6.36364
22 5YB7 FAD 6.81818
23 4REP FAD 10
24 5AE2 FAD 10
25 4WXG 2BO 10
26 4KBA 1QM 10
27 5EXW 7DT 18.1818
Pocket No.: 12; Query (leader) PDB : 2FLI; Ligand: DX5; Similar sites found with APoc: 11
This union binding pocket(no: 12) in the query (biounit: 2fli.bio1) has 22 residues
No: Leader PDB Ligand Sequence Similarity
1 4ZGR NGA GAL 2.27273
2 2QJT AMP 2.27273
3 6H8S FSZ 2.27273
4 6G47 SIA SIA 3.34928
5 5YRF GLC GLC 3.52113
6 2VNO GAL GAL FUC 3.88889
7 4LCQ URQ 5
8 6HKE MLT 5.90909
9 4MBY BGC SIA GAL 7.27273
10 1VBO MAN MAN MAN 10.7383
11 1I7Q BEZ 15.0259
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