Receptor
PDB id Resolution Class Description Source Keywords
2FPU 1.8 Å EC: 3.1.3.15 CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF E.COLI HISB- C WITH HISTIDINOL ESCHERICHIA COLI HISTIDINOL PHOSPHATE PHOSPHATASE HISB BIFUNCTIONAL ENZYME.STRUCTURAL GENOMICS BACTERIAL STRUCTURE GENOMICS MONTREALBACTERIAL STRUCTURAL GENOMICS INITIATIVE BSGI HYDROLASE
Ref.: STRUCTURAL SNAPSHOTS OF ESCHERICHIA COLI HISTIDINOL PHOSPHATE PHOSPHATASE ALONG THE REACTION PATHWAY. J.BIOL.CHEM. V. 281 37930 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:502;
B:501;
B:503;
B:504;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
35.453 Cl [Cl-]
HSO B:509;
Valid;
none;
submit data
142.179 C6 H12 N3 O c1c([...
MG A:507;
B:508;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ZN A:506;
B:505;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2FPU 1.8 Å EC: 3.1.3.15 CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF E.COLI HISB- C WITH HISTIDINOL ESCHERICHIA COLI HISTIDINOL PHOSPHATE PHOSPHATASE HISB BIFUNCTIONAL ENZYME.STRUCTURAL GENOMICS BACTERIAL STRUCTURE GENOMICS MONTREALBACTERIAL STRUCTURAL GENOMICS INITIATIVE BSGI HYDROLASE
Ref.: STRUCTURAL SNAPSHOTS OF ESCHERICHIA COLI HISTIDINOL PHOSPHATE PHOSPHATASE ALONG THE REACTION PATHWAY. J.BIOL.CHEM. V. 281 37930 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2FPU - HSO C6 H12 N3 O c1c([nH+]c....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2FPU - HSO C6 H12 N3 O c1c([nH+]c....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2FPU - HSO C6 H12 N3 O c1c([nH+]c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: HSO; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 HSO 1 1
2 HIS 0.52381 0.846154
3 DHI 0.52381 0.846154
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2FPU; Ligand: HSO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2fpu.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2FPU; Ligand: HSO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2fpu.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2FPU; Ligand: HSO; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2fpu.bio2) has 11 residues
No: Leader PDB Ligand Sequence Similarity
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