Receptor
PDB id Resolution Class Description Source Keywords
2FSH 2 Å EC: 7.-.-.- COMPLEX SECA:AMP-PNP FROM ESCHERICHIA COLI ESCHERICHIA COLI ATPASE DNA-RNA HELICASE PROTEIN TRANSLOCATION SECA PROTEIN TRANSPORT
Ref.: STRUCTURE OF DIMERIC SECA, THE ESCHERICHIA COLI PREPROTEIN TRANSLOCASE MOTOR. J.MOL.BIOL. V. 366 1545 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:900;
B:901;
Valid;
Valid;
none;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2FSH 2 Å EC: 7.-.-.- COMPLEX SECA:AMP-PNP FROM ESCHERICHIA COLI ESCHERICHIA COLI ATPASE DNA-RNA HELICASE PROTEIN TRANSLOCATION SECA PROTEIN TRANSPORT
Ref.: STRUCTURE OF DIMERIC SECA, THE ESCHERICHIA COLI PREPROTEIN TRANSLOCASE MOTOR. J.MOL.BIOL. V. 366 1545 2007
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 2FSG - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2FSH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
3 2FSI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 217 families.
1 2FSG - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2FSH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
3 2FSI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 4YS0 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 2FSG - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 2FSH - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
4 2FSI - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2FSH; Ligand: ANP; Similar sites found: 355
This union binding pocket(no: 1) in the query (biounit: 2fsh.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2ZJ5 ADP 0.00007867 0.51606 1.11111
2 2CE7 ADP 0.000488 0.47395 1.2605
3 1XKV ATP 0.00004653 0.47414 1.51229
4 5I34 GDP 0.002996 0.43326 1.5873
5 1QHG ATP 0.000003328 0.51029 1.65746
6 2OBM ADP 0.001316 0.45739 1.72911
7 1R0X ATP 0.003057 0.42756 1.74825
8 4IHQ ADP 0.004759 0.41841 1.75439
9 4LYA ATP 0.0008647 0.43687 1.78891
10 3TBK ANP 0.000000008201 0.70494 1.8018
11 5MZN ADP 0.00000712 0.56148 1.86916
12 1JWY ADP 0.001314 0.42576 1.87573
13 1JWY GDP 0.001843 0.40926 1.87573
14 5CK5 GDP 0.0000909 0.50009 1.89873
15 1G7S GDP 0.00413 0.40524 2.0202
16 1YQT ADP 0.0007293 0.46812 2.04461
17 3B8I OXL 0.02058 0.40521 2.09059
18 1ZUA NAP 0.02755 0.42821 2.2082
19 1ZUA TOL 0.02755 0.42821 2.2082
20 5M04 GDP 0.001475 0.4426 2.22222
21 5L3W GDP 0.00005724 0.51913 2.28758
22 1SKQ GDP 0.002716 0.43 2.29885
23 3WYA GDP 0.001881 0.42815 2.30415
24 1K6M AGS 0.0004101 0.40306 2.31481
25 1CR1 TTP 0.002836 0.44533 2.36486
26 2NCD ADP 0.0001168 0.50688 2.38095
27 2GK6 ADP 0.000005581 0.56664 2.40385
28 3TK1 GDP 0.0003811 0.47709 2.42424
29 1VKJ A3P 0.004994 0.4331 2.45614
30 1PUJ GNP 0.001406 0.40945 2.48227
31 4P4T GDP 0.001119 0.40646 2.5
32 2VVG ADP 0.00002717 0.54672 2.57143
33 4GID 0GH 0.03796 0.41909 2.57732
34 1SQ5 ADP 0.0002216 0.45991 2.5974
35 4ZKD GDP 0.003048 0.45241 2.60521
36 5GOE GDP 0.0004493 0.43674 2.60664
37 2XT3 ADP 0.00003853 0.53788 2.61628
38 4W93 3L9 0.01741 0.42134 2.62097
39 2I4I AMP 0.0009101 0.41683 2.63789
40 5M7P ADP 0.0007614 0.47161 2.64317
41 5BQ5 ADP BEF 0.002866 0.408 2.6455
42 4LC1 GDP 0.0005036 0.45323 2.67062
43 3COB ADP 0.00007434 0.52183 2.71003
44 4YMU ATP 0.0008846 0.45315 2.72727
45 4AG5 ADP 0.0001916 0.49727 2.80612
46 3FWY ADP 0.001144 0.40771 2.86624
47 3IO3 ADP 0.0008423 0.40589 2.87356
48 4RD0 GDP 0.002782 0.44764 2.89157
49 2WHX ADP 0.00032 0.48554 2.91262
50 1XP8 AGS 0.007039 0.41032 2.93083
51 2IS6 ADP 0.00007413 0.49219 2.94118
52 4LJ9 ACP 0.001738 0.43057 2.94985
53 4KBF AMP 0.00007546 0.50392 3.0137
54 4WZA ADP 0.0041 0.47681 3.06513
55 4WZA ACP 0.0041 0.47681 3.06513
56 4XGU ADP 0.0002124 0.43607 3.06604
57 1GOJ ADP 0.00001936 0.55679 3.09859
58 3MD0 GDP 0.0005369 0.46346 3.09859
59 5I0H ADP BEF 0.001028 0.46725 3.10391
60 5IRN ADP 0.0003264 0.48501 3.13253
61 1F9V ADP 0.0001 0.47404 3.17003
62 5UQW GDP 0.001236 0.46896 3.1746
63 5FJJ MAN 0.02411 0.41801 3.20665
64 4ZG4 VO4 ADP 0.0007339 0.47851 3.27225
65 4B47 GDP 0.001858 0.43784 3.30579
66 3BOS CDP 0.002617 0.42185 3.30579
67 1FNN ADP 0.0007614 0.40393 3.3419
68 4LX0 BEF GDP 0.0008568 0.48047 3.38983
69 4QDI ATP 0.003725 0.42869 3.38983
70 4BQS K2Q 0.0001001 0.54107 3.40909
71 4BQS ADP 0.0001813 0.47321 3.40909
72 2AWN ADP 0.00001991 0.56345 3.41207
73 3EWA ANP 0.001974 0.43939 3.41615
74 4PX9 ADP 0.0000123 0.54134 3.42466
75 1KO8 6PG 0.0004017 0.48534 3.42857
76 5HCN GCP 0.000481 0.44553 3.44828
77 2FAH GDP 0.002267 0.40534 3.45395
78 4IEE AGS 0.009078 0.40505 3.46939
79 5XDR ADP 0.0007179 0.43507 3.47826
80 5LTJ ADP 0.0002335 0.48672 3.5014
81 5WDR GNP 0.00355 0.44904 3.50877
82 2IYL GDP 0.00002213 0.51485 3.52113
83 5FG3 GDP 0.002514 0.4316 3.5313
84 1CLU DBG 0.001592 0.48508 3.61446
85 5FTB ANP 0.0002347 0.44937 3.69515
86 5FHD ADP ALF 0.0005038 0.41035 3.69515
87 4A4Z ANP 0.000002576 0.55638 3.75147
88 3VMF GTP 0.003252 0.44939 3.75335
89 4KFU ACP 0.000413 0.48071 3.77358
90 1M7G AV2 0.0002536 0.47892 3.79147
91 1M7G ADP 0.00384 0.45027 3.79147
92 4QRH 0O2 0.0008632 0.47102 3.80952
93 3DEF GDP 0.0006282 0.4238 3.81679
94 1OYY AGS 0.00007946 0.4918 3.82409
95 3A4M ADP 0.0004031 0.4759 3.84615
96 1GWN GTP 0.003008 0.44406 3.90244
97 3B7G ANP 0.000005954 0.52913 3.91304
98 4U5X GNP 0.00141 0.40484 3.93258
99 2JLR ANP 0.0008284 0.41589 3.99113
100 2D2F ADP 0.004336 0.42813 4
101 5KSZ GCP 0.00104 0.42518 4.00943
102 2HT6 GDP 0.001047 0.44967 4.02299
103 1LVG ADP 0.0002692 0.48446 4.0404
104 4R98 GNH 0.002648 0.43327 4.05904
105 3U6B GDP 0.001431 0.44323 4.06091
106 5JBQ GDP 0.001741 0.44199 4.06091
107 3U6K GDP 0.002161 0.42554 4.06091
108 4G5G GDP 0.002156 0.42541 4.06091
109 3AB3 GDP 0.007708 0.4237 4.06504
110 1D8T GDP 0.002513 0.42251 4.07125
111 2BVN GNP 0.002409 0.40287 4.07125
112 4PTN PYR 0.005503 0.43573 4.08163
113 1R6B ADP 0.0008264 0.43811 4.08971
114 5H56 TYD 0.001195 0.47781 4.10256
115 5H56 ADP 0.001195 0.47781 4.10256
116 1DAR GDP 0.001484 0.43396 4.10317
117 3Q72 GNP 0.00207 0.4356 4.21687
118 4GOJ GNP 0.002322 0.45156 4.2328
119 3ZFD ANP 0.0004122 0.47751 4.2735
120 2OFW ADX 0.0007784 0.49817 4.32692
121 4LH7 1X8 0.00716 0.42676 4.33437
122 3AQ4 GDP 0.0009107 0.43303 4.34783
123 4E03 ADP 0.00269 0.41694 4.36893
124 4RZ3 ADP 0.002895 0.44085 4.40678
125 3W5J GDP 0.0008768 0.46473 4.41176
126 1FZQ GDP 0.001729 0.42937 4.41989
127 1FP6 ADP 0.0009425 0.41861 4.49827
128 3WXM GTP 0.007291 0.43159 4.52128
129 4PPF FLC 0.0001959 0.5098 4.57143
130 1JI0 ATP 0.003333 0.43108 4.58333
131 4D81 ADP 0.0001637 0.49966 4.59364
132 4DKX GDP 0.002527 0.42211 4.62963
133 2XAU ADP 0.000132 0.45517 4.65718
134 5V22 SAH 0.006828 0.42446 4.7138
135 2C04 GCP 0.001063 0.40936 4.7138
136 2J0V GDP 0.002468 0.43733 4.71698
137 1G41 ADP 0.0001652 0.45717 4.72973
138 2WJG GDP 0.001823 0.42913 4.78723
139 3BP1 GUN 0.01634 0.40427 4.82759
140 1VG0 GDP 0.0007083 0.46857 4.83092
141 1RE0 GDP 0.001537 0.44176 4.87805
142 1RYH GNP 0.002403 0.40794 4.92611
143 1B0U ATP 0.001488 0.40544 4.96183
144 3SFV GDP 0.0003826 0.48859 4.97238
145 2PEZ DAT 0.000577 0.49708 5.02793
146 2PEZ GGZ 0.000577 0.49708 5.02793
147 2RCN GDP 0.001007 0.43988 5.02793
148 1J99 AND 0.0308 0.4083 5.11945
149 2ZE7 DST 0.005377 0.43984 5.13834
150 2ZE7 AMP 0.007285 0.4316 5.13834
151 5E95 GDP 0.001115 0.4049 5.15464
152 1T5C ADP 0.00007558 0.52235 5.15759
153 1I4D GDP 0.00306 0.42754 5.20833
154 4HSE ADP 0.0006395 0.44274 5.28967
155 3RAB GNP 0.002736 0.4532 5.32544
156 4D0N GDP 0.001335 0.44752 5.36193
157 1MH1 GNP 0.001458 0.46872 5.37634
158 3CPJ GDP 0.0003767 0.4296 5.38117
159 4NON GDP 0.00158 0.43121 5.38462
160 3W9F I3P 0.01631 0.42071 5.39273
161 1VG9 GDP 0.0005511 0.46873 5.40541
162 1VG1 GDP 0.0005334 0.44155 5.40541
163 2WJH GDP 0.0007977 0.46099 5.42169
164 2WJH FLC 0.003316 0.43353 5.42169
165 2Q2Y MKR 0.001641 0.48105 5.44959
166 2Q2Y ADP 0.001724 0.48105 5.44959
167 2CBZ ATP 0.0003032 0.48981 5.48523
168 3NHB ADP 0.0003528 0.4842 5.55556
169 3N5C GDP 0.001823 0.42882 5.55556
170 1NJF ADP 0.0004247 0.48414 5.6
171 1NJF AGS 0.001422 0.46221 5.6
172 1KK1 GNP 0.004144 0.42127 5.60976
173 1NY5 ADP 0.0000915 0.44742 5.68475
174 5K5Z ANP 0.001394 0.46631 5.73248
175 1G6O ADP 0.00115 0.41836 5.75758
176 4J0Q GDP 0.002267 0.43373 5.77367
177 4WOP CTP 0.0001872 0.50401 5.77778
178 1OW3 GDP 0.003866 0.43467 5.78512
179 5KSP GDP 0.00115 0.42994 5.78947
180 4DCT GDP 0.001069 0.42995 5.92105
181 1OXV ANP 0.0007944 0.45537 5.94901
182 4PFO ADP 0.000903 0.4776 5.96447
183 1Y63 ADP 0.0006771 0.44728 5.97826
184 4MKF AP5 0.005267 0.45634 5.99078
185 3UIE ANP 0.000261 0.44556 6
186 5HR5 ADP 0.0006088 0.47416 6.02637
187 5HR5 FLC 0.01263 0.42745 6.02637
188 5VGR GDP 0.001337 0.4047 6.03248
189 5HPY GDP 0.004659 0.43068 6.03448
190 3IUY AMP 0.0004203 0.45866 6.14035
191 2C9O ADP 0.0005766 0.40287 6.14035
192 2A5J GDP 0.0005907 0.43106 6.28272
193 5LB3 ADP 0.0000004092 0.61152 6.29213
194 1V8K ANP 0.0008513 0.44322 6.34146
195 4ITM ATP 0.02123 0.40792 6.34921
196 1U0J ADP 0.007846 0.40807 6.36704
197 2OG2 MLI 0.0001282 0.49665 6.40669
198 2ZPA ADP 0.00004953 0.53027 6.40835
199 5E5U MLI 0.01037 0.42538 6.43939
200 4PJ3 ANP 0.000001066 0.53546 6.44783
201 4BAS GNP 0.00123 0.46535 6.53266
202 1W7J ADP BEF 0.0003804 0.42072 6.62252
203 2CHG ANP 0.001746 0.40528 6.63717
204 1OFH ADP 0.0001961 0.45495 6.77419
205 1JBW ACQ 0.02439 0.41251 6.7757
206 1S8F GDP 0.0008451 0.42624 6.77966
207 5MVR ADP 0.001091 0.45172 6.79012
208 2DPY ADP 0.0007791 0.46192 6.84932
209 2Y65 ADP 0.0001824 0.45068 6.84932
210 2ZR9 DTP 0.003646 0.41425 6.87679
211 3R96 ACO 0.04175 0.40537 6.91489
212 3DKP ADP 0.000005497 0.54287 6.93878
213 3FKQ ATP 0.000885 0.4131 6.97051
214 5JCZ GDP 0.0007012 0.40448 7.0529
215 4XVU ATP 0.002148 0.45508 7.06215
216 4XTR ATP 0.00248 0.45195 7.06215
217 4XTR ADP 0.002028 0.45057 7.06215
218 3DZD ADP 0.0001532 0.44607 7.06522
219 3T1O GDP 0.003685 0.4313 7.07071
220 4Q1A UDP 0.03239 0.45569 7.14286
221 4Q1A 2XZ 0.03239 0.45569 7.14286
222 5IFS ADP 0.0007758 0.46418 7.173
223 5G41 AP5 0.006385 0.45573 7.17489
224 4R43 GDP 0.0009104 0.44305 7.1885
225 3GJ4 GDP 0.0007259 0.4462 7.23982
226 3GJ0 GDP 0.0008922 0.44215 7.23982
227 3GJ3 GDP 0.0009809 0.4405 7.23982
228 3GJ5 GDP 0.0009946 0.43032 7.23982
229 1Z6T ADP 0.0001107 0.44648 7.2758
230 1MKY GDP 0.000765 0.44557 7.28929
231 4U00 ADP 0.0001073 0.44377 7.37705
232 5BXQ GDP 0.0008829 0.45886 7.40741
233 3GJX GTP 0.004907 0.44187 7.40741
234 1Z0A GDP 0.0003472 0.44218 7.47126
235 5L3R GCP 0.0000729 0.41518 7.50853
236 1G3Q ADP 0.004236 0.41063 7.59494
237 3B9Q MLI 0.0002135 0.50352 7.61589
238 3E70 GDP 0.00001671 0.50645 7.62195
239 1YTM ATP 0.0006475 0.40527 7.70677
240 3A1S GDP 0.003393 0.40895 7.75194
241 1DS6 GDP 0.001883 0.4274 7.77778
242 2CJW GDP 0.0003923 0.4584 7.8125
243 3EC1 GDP 0.002731 0.41269 7.85908
244 1BG2 ADP 0.0001279 0.44276 8
245 2G77 GDP 0.001006 0.41043 8.08081
246 2HCJ GDP 0.001719 0.43944 8.10811
247 5X40 ACP 0.001636 0.46102 8.21918
248 3IIJ ADP 0.0006264 0.44931 8.33333
249 1S9D GDP 0.0007356 0.43657 8.37438
250 1Z0F GDP 0.0005766 0.44216 8.37989
251 2QZ4 ADP 0.0004055 0.44053 8.39695
252 5KUT GDP 0.0004385 0.47352 8.46561
253 3EZ2 ADP 0.007956 0.40778 8.54271
254 1F6B GDP 0.002055 0.41716 8.58586
255 4YLG GDP 0.001447 0.45567 8.67052
256 4D0G GTP 0.001751 0.45768 8.69565
257 1JJV ATP 0.000129 0.5045 8.73786
258 2ZFI ADP 0.0003742 0.45963 8.74317
259 1YRB GDP 0.0003599 0.43048 8.77863
260 2EFE GNH 0.0008539 0.41466 8.83978
261 5IRC GDP 0.005043 0.42467 8.95522
262 2X77 GDP 0.001915 0.42202 8.99471
263 5L3V GDP 0.00001702 0.49403 9.0301
264 5L3S GNP 0.0000588 0.53566 9.0604
265 3CNL GNP 0.006376 0.41236 9.16031
266 3GJ7 GDP 0.0009661 0.44068 9.18367
267 4V03 ADP 0.006423 0.41956 9.33852
268 3Q85 GNP 0.0004534 0.45559 9.46746
269 4FRZ ADP 0.00009593 0.51209 9.58549
270 3H4S ADP 0.00006462 0.46878 9.58549
271 2UZI GTP 0.002364 0.45642 9.61539
272 4YDS ATP 0.001083 0.45494 9.64912
273 5EP2 AZU 0.0002456 0.49816 9.76562
274 3LRE ADP 0.00001822 0.55967 9.85915
275 1W0J ADP 0.001682 0.45022 9.92647
276 1W0J ADP BEF 0.003167 0.44099 9.92647
277 1OIV GDP 0.0007417 0.48194 9.94764
278 1OIX GDP 0.000855 0.47881 9.94764
279 3NOJ PYR 0.01675 0.41095 10.084
280 5WRI A3P 0.01851 0.40636 10.3125
281 1ZX5 LFR 0.0002846 0.50501 10.3333
282 5SZH GNP 0.0009493 0.47821 10.3448
283 2ODE ALF GDP 0.008523 0.43247 10.6383
284 3X1Z GNP 0.005027 0.44283 10.7784
285 5WRJ A3P 0.01159 0.41982 10.8911
286 4PC3 GDP 0.0008605 0.42372 10.9929
287 2KIN ADP 0.0001078 0.44517 11
288 1KSH GDP 0.002869 0.44508 11.1842
289 3T5G GDP 0.002475 0.43971 11.1842
290 5UWU GNP 0.002461 0.45714 11.1888
291 5UWP GNP 0.0027 0.45664 11.1888
292 5DI9 GNP 0.002966 0.45455 11.1888
293 1SVI GDP 0.0004725 0.46609 11.2821
294 4QOS ADP 0.0004681 0.43706 11.3208
295 2EW1 GNP 0.001013 0.47147 11.4428
296 4TMK T5A 0.00039 0.50736 11.7371
297 3KJI ADP 0.001376 0.45448 11.811
298 2D7D ADP 0.000000006432 0.67273 12.5
299 2GDJ ANP 0.004239 0.41221 12.5
300 3ZIA ATP 0.0008121 0.43931 12.6984
301 3ZIA ADP 0.001873 0.41226 12.6984
302 2WIC GNP 0.001398 0.42653 12.7341
303 3PQC GDP 0.0009697 0.42491 12.8205
304 3LXR GDP 0.002068 0.40944 13.0208
305 4TTQ ATP 0.001176 0.43878 13.0233
306 1MR3 G3D 0.000409 0.44699 13.2597
307 2FFQ GSP 0.008101 0.43076 13.4503
308 5GRF ADP 0.009332 0.42905 13.5593
309 4HI0 GDP 0.000247 0.4153 13.5678
310 4CVN ADP 0.0001202 0.50156 13.6126
311 1G6H ADP 0.002958 0.43841 13.6187
312 1ZJ6 G3D 0.00185 0.4202 13.9037
313 1YZG GDP 0.0009642 0.43165 13.9665
314 3R5J ACE ALA ASP VAL ALA ASA 0.02287 0.40007 14.2857
315 3M1I GTP 0.002763 0.45458 14.6597
316 1XX6 ADP 0.005786 0.42282 15.1832
317 2PL3 ADP 0.000002077 0.57801 15.2542
318 1RRC ADP 0.0001843 0.44984 15.2824
319 3Q9L ATP 0.00285 0.41465 15.3846
320 2BCG GDP 0.000692 0.40387 15.534
321 4DID GDP 0.002608 0.41246 15.544
322 5N69 ADP 0.0005626 0.42507 15.5779
323 2NGR GDP 0.002643 0.41276 15.7068
324 2WMO GTP 0.001421 0.41895 15.7895
325 4YC7 GNP 0.004772 0.4359 16.0221
326 2A9K GDP 0.002057 0.44816 16.0428
327 2VB6 ADP BEF 0.0008635 0.47496 16.1074
328 1JJ7 ADP 0.0001715 0.50831 16.5385
329 3AB4 THR 0.007465 0.4091 16.8539
330 4FCW ADP 0.0008667 0.43603 17.3633
331 1B7T ADP 0.001188 0.41836 17.9487
332 1KY3 GDP 0.0004377 0.42638 18.1319
333 1KK8 BEF ADP 0.0006674 0.41132 18.1818
334 3GJ8 GDP 0.0009999 0.43029 18.4783
335 5UWR GNP 0.002578 0.45611 18.5185
336 3B5J 12D 0.001144 0.45377 18.5185
337 4WZ6 ATP 0.0005516 0.47369 18.6207
338 5EE5 GTP 0.0008692 0.47289 19.883
339 1HTW ADP 0.0008325 0.46009 20.2532
340 4P3Y GDP 0.001679 0.43993 21.4286
341 3WY9 GDP 0.003607 0.42414 21.875
342 4QM7 GTP 0.0002219 0.46879 22.2222
343 4C4P GNP 0.0008341 0.48107 22.4299
344 3BER AMP 0.001097 0.44033 22.49
345 4XOI GTP 0.006665 0.43199 22.963
346 2HV8 GTP 0.0007929 0.48046 23.4375
347 2PZE ATP 0.0002277 0.4967 24.4541
348 1VHT BA3 0.0002185 0.44764 28.4404
349 1QHH ATP 0.00000281 0.53925 32.1739
350 3CH5 GDP 0.001156 0.42773 34.6154
351 5UWT GNP 0.002408 0.45762 39.1304
352 2V7Q ADP 0.002346 0.42623 40
353 2V7Q ATP 0.001128 0.42092 40
354 2QN6 GDP 0.001889 0.4375 44.086
355 5UWI GNP 0.002547 0.45638 44.4444
Pocket No.: 2; Query (leader) PDB : 2FSH; Ligand: ANP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2fsh.bio1) has 14 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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