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Receptor
PDB id Resolution Class Description Source Keywords
2FYD 2 Å EC: 2.4.1.22 CATALYTIC DOMAIN OF BOVINE BETA 1, 4-GALACTOSYLTRANSFERASE IN COMPLEX WITH ALPHA-LACTALBUMIN, GLUCOSE, MN, AND UDP-N- A CETYLGALACTOSAMINE MUS MUSCULUS LACTOSE SYTHASE CATALYTIC INTERMEDIATE TRANSFERASE
Ref.: STRUCTURAL SNAPSHOTS OF BETA-1,4-GALACTOSYLTRANSFERASE-I ALONG THE KINETIC PATHWAY. J.MOL.BIOL. V. 357 1619 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BGC B:403;
D:530;
Valid;
Valid;
none;
none;
submit data
180.156 C6 H12 O6 C([C@...
CA A:124;
C:526;
Part of Protein;
Part of Protein;
none;
none;
submit data
40.078 Ca [Ca+2...
MES A:805;
C:806;
Invalid;
Invalid;
none;
none;
submit data
195.237 C6 H13 N O4 S C1COC...
MN B:405;
D:527;
Part of Protein;
Part of Protein;
none;
none;
submit data
54.938 Mn [Mn+2...
NGA B:404;
D:529;
Valid;
Valid;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
PG4 A:850;
C:851;
Invalid;
Invalid;
none;
none;
submit data
194.226 C8 H18 O5 C(COC...
UDP B:406;
D:528;
Valid;
Valid;
none;
none;
submit data
404.161 C9 H14 N2 O12 P2 C1=CN...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
1YRO 1.9 Å EC: 2.4.1.22 CRYSTAL STRUCTURE OF BETA14,-GALACTOSYLTRANSFERASE MUTANT AR COMPLEX WITH ALPHA-LACTALBUMIN IN THE PRESENCE OF UDP-GALACM N MUS MUSCULUS ARG228LYS MUTATION; UDP-GAL COMPLEX TRANSFERASE ACTIVATOR- TRANSFERASE COMPLEX
Ref.: MUTATION OF ARGININE 228 TO LYSINE ENHANCES THE GLUCOSYLTRANSFERASE ACTIVITY OF BOVINE BETA-1,4-GALACTOSYLTRANSFERASE I BIOCHEMISTRY V. 44 3202 2005
Members (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 1NHE - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
2 1YRO - GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
3 1NF5 - BGC C6 H12 O6 C([C@@H]1[....
4 1O23 - GUD C15 H24 N2 O17 P2 C1=CN(C(=O....
5 2FYC - GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
6 1PZY - NAG C8 H15 N O6 CC(=O)N[C@....
7 1NMM - NAG C8 H15 N O6 CC(=O)N[C@....
8 1NWG - BGN C10 H19 N O6 CCCC(=O)N[....
9 2FYD - NGA C8 H15 N O6 CC(=O)N[C@....
10 1NKH - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
11 1OQM - UD2 C17 H27 N3 O17 P2 CC(=O)N[C@....
12 1NQI - NAG C8 H15 N O6 CC(=O)N[C@....
70% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1NHE - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
2 1YRO - GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
3 1NF5 - BGC C6 H12 O6 C([C@@H]1[....
4 1O23 - GUD C15 H24 N2 O17 P2 C1=CN(C(=O....
5 2FYC - GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
6 1PZY - NAG C8 H15 N O6 CC(=O)N[C@....
7 1NMM - NAG C8 H15 N O6 CC(=O)N[C@....
8 1NWG - BGN C10 H19 N O6 CCCC(=O)N[....
9 2FYD - NGA C8 H15 N O6 CC(=O)N[C@....
10 1NKH - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
11 1OQM - UD2 C17 H27 N3 O17 P2 CC(=O)N[C@....
12 1NQI - NAG C8 H15 N O6 CC(=O)N[C@....
50% Homology Family (12)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 1NHE - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
2 1YRO - GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
3 1NF5 - BGC C6 H12 O6 C([C@@H]1[....
4 1O23 - GUD C15 H24 N2 O17 P2 C1=CN(C(=O....
5 2FYC - GDU C15 H24 N2 O17 P2 C1=CN(C(=O....
6 1PZY - NAG C8 H15 N O6 CC(=O)N[C@....
7 1NMM - NAG C8 H15 N O6 CC(=O)N[C@....
8 1NWG - BGN C10 H19 N O6 CCCC(=O)N[....
9 2FYD - NGA C8 H15 N O6 CC(=O)N[C@....
10 1NKH - UDP C9 H14 N2 O12 P2 C1=CN(C(=O....
11 1OQM - UD2 C17 H27 N3 O17 P2 CC(=O)N[C@....
12 1NQI - NAG C8 H15 N O6 CC(=O)N[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BGC; Similar ligands found: 142
No: Ligand ECFP6 Tc MDL keys Tc
1 WOO 1 1
2 GLC 1 1
3 BGC 1 1
4 ALL 1 1
5 BMA 1 1
6 GXL 1 1
7 GIV 1 1
8 GAL 1 1
9 MAN 1 1
10 GLA 1 1
11 Z6J 0.653846 0.866667
12 32O 0.653846 0.866667
13 RIB 0.653846 0.866667
14 FUB 0.653846 0.866667
15 AHR 0.653846 0.866667
16 MLB 0.511628 0.848485
17 GLC GLC 0.511628 0.848485
18 BGC GLC 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 BMA GLA 0.511628 0.848485
23 GLA BGC 0.511628 0.848485
24 MAN MAN 0.511628 0.848485
25 GLA GLC 0.511628 0.848485
26 BMA MAN 0.511628 0.848485
27 GAL GLC 0.511628 0.848485
28 GAL GAL 0.511628 0.848485
29 LAK 0.511628 0.848485
30 GLC BGC 0.511628 0.848485
31 YDR 0.5 0.8
32 GLC GLC GLC GLC BGC 0.488889 0.848485
33 GLC GLC GLC 0.488889 0.848485
34 MAN MAN MAN 0.488889 0.848485
35 BMA MAN MAN 0.488889 0.848485
36 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
37 EMZ 0.472222 0.794118
38 BG6 0.461538 0.675
39 BGP 0.461538 0.675
40 G6P 0.461538 0.675
41 M6P 0.461538 0.675
42 M6D 0.461538 0.675
43 A6P 0.461538 0.675
44 GAF 0.457143 0.875
45 SHG 0.457143 0.875
46 2FG 0.457143 0.875
47 G2F 0.457143 0.875
48 2H5 0.457143 0.875
49 GCS 0.457143 0.777778
50 1GN 0.457143 0.777778
51 X6X 0.457143 0.777778
52 PA1 0.457143 0.777778
53 95Z 0.457143 0.777778
54 G3F 0.457143 0.875
55 NGR 0.454545 0.848485
56 MAL 0.454545 0.848485
57 MAN GLC 0.454545 0.848485
58 GAL BGC 0.454545 0.848485
59 GLA GLA 0.454545 0.848485
60 BGC BMA 0.454545 0.848485
61 M3M 0.454545 0.848485
62 GLA GAL 0.454545 0.848485
63 MAB 0.454545 0.848485
64 GLC GAL 0.454545 0.848485
65 B2G 0.454545 0.848485
66 LBT 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 LAT 0.454545 0.848485
69 BGC GAL 0.454545 0.848485
70 CBI 0.454545 0.848485
71 CBK 0.454545 0.848485
72 N9S 0.454545 0.848485
73 LB2 0.454545 0.848485
74 3MG 0.444444 0.875
75 TCB 0.444444 0.8
76 GLC SGC 0.444444 0.8
77 YIO 0.441176 0.870968
78 2GS 0.432432 0.875
79 2M4 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 MAN BMA BMA 0.416667 0.848485
84 BMA MAN BMA 0.416667 0.848485
85 CTR 0.416667 0.848485
86 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
87 GLA GAL BGC 0.416667 0.848485
88 CE5 0.416667 0.848485
89 MLR 0.416667 0.848485
90 CE6 0.416667 0.848485
91 MT7 0.416667 0.848485
92 BMA BMA BMA 0.416667 0.848485
93 GLC BGC BGC BGC BGC 0.416667 0.848485
94 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
95 BGC BGC BGC BGC BGC 0.416667 0.848485
96 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
97 BGC GLC GLC 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 MAN BMA BMA BMA BMA 0.416667 0.848485
100 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
101 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
102 MAN BMA BMA BMA BMA BMA 0.416667 0.848485
103 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 CTT 0.416667 0.848485
107 GLA GAL GLC 0.416667 0.848485
108 MTT 0.416667 0.848485
109 GLC BGC BGC BGC 0.416667 0.848485
110 GLC GLC BGC 0.416667 0.848485
111 CEY 0.416667 0.848485
112 B4G 0.416667 0.848485
113 CE8 0.416667 0.848485
114 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
115 GAL FUC 0.416667 0.848485
116 DXI 0.416667 0.848485
117 GLC BGC GLC 0.416667 0.848485
118 CT3 0.416667 0.848485
119 GAL GAL GAL 0.416667 0.848485
120 GLC GLC GLC GLC GLC 0.416667 0.848485
121 BGC BGC BGC BGC 0.416667 0.848485
122 BGC BGC BGC 0.416667 0.848485
123 BGC BGC GLC 0.416667 0.848485
124 CEX 0.416667 0.848485
125 GLC GAL GAL 0.416667 0.848485
126 BGC GLC GLC GLC GLC 0.416667 0.848485
127 GLC BGC BGC 0.416667 0.848485
128 GS1 GLC GS1 0.408163 0.8
129 SGC SGC BGC 0.408163 0.8
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 TRE 0.405405 0.848485
135 NDG 0.404762 0.7
136 NGA 0.404762 0.7
137 NAG 0.404762 0.7
138 HSQ 0.404762 0.7
139 A2G 0.404762 0.7
140 BM3 0.404762 0.7
141 FUB AHR AHR 0.4 0.764706
142 AHR AHR AHR AHR AHR AHR 0.4 0.764706
Ligand no: 2; Ligand: NGA; Similar ligands found: 105
No: Ligand ECFP6 Tc MDL keys Tc
1 NGA 1 1
2 NAG 1 1
3 A2G 1 1
4 BM3 1 1
5 HSQ 1 1
6 NDG 1 1
7 BGN 0.638298 0.888889
8 SIZ 0.630435 0.906977
9 YX1 0.625 0.65
10 STZ 0.612245 0.65
11 4QY 0.591837 0.735849
12 BMX 0.591837 0.735849
13 16G 0.591837 0.735849
14 9C1 0.58 0.886364
15 SNG 0.5625 0.866667
16 NGS 0.54902 0.661017
17 NDG NAG 0.54386 0.833333
18 CBS 0.54386 0.833333
19 NAG GDL 0.54386 0.833333
20 CBS CBS 0.54386 0.833333
21 ASG 0.538462 0.661017
22 BG8 0.537037 0.906977
23 MAG 0.530612 0.909091
24 2F8 0.530612 0.909091
25 NDG GAL 0.517857 0.888889
26 NLC 0.517857 0.888889
27 GAL NDG 0.517857 0.888889
28 NAG A2G 0.517241 0.833333
29 4V5 0.517241 0.829787
30 NAG NGA 0.517241 0.833333
31 4UZ 0.508475 0.808511
32 NAG NAG NAG NAG NDG 0.508197 0.816327
33 NDG NAG NAG NAG 0.508197 0.816327
34 NAG NAG NDG 0.508197 0.816327
35 NAG NAG NDG NAG 0.508197 0.816327
36 CTO 0.508197 0.816327
37 NDG NAG NAG NDG 0.508197 0.816327
38 NAG NAG NAG NDG 0.508197 0.816327
39 NDG NAG NAG 0.508197 0.816327
40 NAG NAG NAG NAG NAG 0.508197 0.816327
41 NAG NAG NAG NAG NAG NAG 0.508197 0.816327
42 NAG NAG NAG NAG NAG NAG NAG NAG 0.508197 0.816327
43 MQG 0.5 0.698113
44 NBG 0.5 0.951219
45 GAL NGA 0.491228 0.888889
46 A2G GAL 0.491228 0.888889
47 GAL A2G 0.491228 0.888889
48 AMU 0.490909 0.930233
49 NG1 0.490566 0.754717
50 GN1 0.490566 0.754717
51 NAG GAL 0.474576 0.888889
52 GAL NAG 0.474576 0.888889
53 NAG FUC 0.474576 0.866667
54 NAG GAL NAG 0.455882 0.833333
55 3YW 0.448276 0.930233
56 GLA GAL NAG 0.446154 0.888889
57 MAN BMA NAG 0.446154 0.888889
58 NGA GAL 0.428571 0.869565
59 FUC GAL NAG 0.426471 0.869565
60 GAL NAG FUC 0.426471 0.869565
61 DR2 0.426471 0.869565
62 NAG GAL FUC 0.426471 0.869565
63 NDG GAL FUC 0.426471 0.869565
64 FUC GAL NDG 0.426471 0.869565
65 FUL GAL NAG 0.426471 0.869565
66 G6S NAG 0.426471 0.645161
67 TNR 0.42623 0.833333
68 GYU 0.42623 0.740741
69 GAL NGA A2G 0.424242 0.833333
70 NAG BDP 0.421875 0.851064
71 NAG MBG 0.419355 0.851064
72 NGA GAL BGC 0.41791 0.888889
73 NAG NDG 0.415385 0.784314
74 NAG NAG 0.415385 0.784314
75 AZC 0.415094 0.795918
76 SN5 SN5 0.412698 0.705882
77 A2G MBG 0.412698 0.851064
78 MBG A2G 0.412698 0.851064
79 HS2 0.411765 0.8125
80 5AX 0.411765 0.866667
81 NAG MAN BMA 0.411765 0.888889
82 6ZC 0.409091 0.655738
83 LEC 0.409091 0.655738
84 TCG 0.408451 0.689655
85 GAL BGC NAG GAL 0.408451 0.888889
86 NAG MAN 0.40625 0.851064
87 WOO 0.404762 0.7
88 MAN 0.404762 0.7
89 GAL 0.404762 0.7
90 BGC 0.404762 0.7
91 BMA 0.404762 0.7
92 GLA 0.404762 0.7
93 ALL 0.404762 0.7
94 GLC 0.404762 0.7
95 GXL 0.404762 0.7
96 GIV 0.404762 0.7
97 NAG AMU 0.402778 0.8
98 NAG MUB 0.402778 0.8
99 NAG A2G GAL 0.402778 0.833333
100 A2G GAL FUC 0.4 0.869565
101 FUC GLA A2G 0.4 0.869565
102 DR3 0.4 0.869565
103 A2G GLA FUC 0.4 0.869565
104 NGA GAL FUC 0.4 0.869565
105 FUC GAL A2G 0.4 0.869565
Ligand no: 3; Ligand: UDP; Similar ligands found: 117
No: Ligand ECFP6 Tc MDL keys Tc
1 UDP 1 1
2 UTP 0.892308 1
3 UNP 0.8 0.970149
4 U5P 0.78125 0.984615
5 U 0.78125 0.984615
6 UPU 0.72973 0.940298
7 2KH 0.722222 0.970149
8 44P 0.720588 0.955882
9 UFM 0.717949 0.941176
10 GDU 0.717949 0.941176
11 URM 0.717949 0.927536
12 660 0.717949 0.927536
13 UPG 0.717949 0.941176
14 GUD 0.717949 0.941176
15 UDP UDP 0.714286 0.939394
16 UPP 0.705128 0.941176
17 UDH 0.705128 0.864865
18 U2F 0.691358 0.888889
19 UFG 0.691358 0.888889
20 UPF 0.691358 0.888889
21 UAD 0.670732 0.941176
22 UDX 0.670732 0.941176
23 3UC 0.658824 0.888889
24 USQ 0.654762 0.820513
25 UGB 0.654762 0.955224
26 UGA 0.654762 0.955224
27 G3N 0.647059 0.914286
28 UDM 0.636364 0.914286
29 URI 0.625 0.863636
30 UD1 0.622222 0.927536
31 UD2 0.622222 0.927536
32 Y6W 0.607143 0.888889
33 CDP 0.605263 0.942029
34 HP7 0.591398 0.941176
35 UD7 0.591398 0.927536
36 MJZ 0.585106 0.914286
37 IUG 0.583333 0.810127
38 F5G 0.578947 0.927536
39 12V 0.578947 0.901408
40 HWU 0.578947 0.901408
41 F5P 0.578947 0.914286
42 UD4 0.578947 0.914286
43 CJB 0.573529 0.820895
44 UDZ 0.571429 0.853333
45 DUD 0.571429 0.913043
46 UP5 0.571429 0.853333
47 U U 0.563218 0.955224
48 EPZ 0.56 0.914286
49 5GW 0.559524 0.942029
50 EPU 0.554455 0.901408
51 EEB 0.554455 0.901408
52 U3P 0.547945 0.939394
53 UA3 0.547945 0.939394
54 4TC 0.544554 0.831169
55 HF4 0.54321 0.942029
56 CTP 0.54321 0.942029
57 CSQ 0.531915 0.851351
58 CSV 0.531915 0.851351
59 DUT 0.52439 0.913043
60 4GW 0.516484 0.915493
61 UMA 0.513761 0.914286
62 U4S 0.513158 0.753425
63 U2P 0.506667 0.954545
64 U2S 0.5 0.767123
65 U3S 0.5 0.753425
66 PUP 0.48913 0.913043
67 U21 0.486957 0.810127
68 U20 0.486957 0.810127
69 U22 0.486957 0.790123
70 DKX 0.486486 0.746479
71 U1S 0.482759 0.75
72 A U 0.481132 0.805195
73 2QR 0.478632 0.822785
74 5FU 0.474359 0.914286
75 G U 0.472222 0.7875
76 8OD 0.47191 0.851351
77 C5G 0.468085 0.888889
78 7XL 0.465909 0.888889
79 U U U U 0.461538 0.940298
80 UMF 0.461538 0.857143
81 G8D 0.460674 0.855263
82 UTP U U U 0.456522 0.895522
83 2TU 0.452055 0.774648
84 4RA 0.451613 0.855263
85 C2G 0.450549 0.901408
86 DU 0.45 0.898551
87 UMP 0.45 0.898551
88 C 0.45 0.927536
89 CAR 0.45 0.927536
90 C5P 0.45 0.927536
91 UAG 0.448 0.864865
92 CDC 0.446809 0.777778
93 5BU 0.444444 0.914286
94 UD0 0.444444 0.844156
95 N3E 0.440476 0.733333
96 UC5 0.440476 0.9
97 UUA 0.438356 0.772727
98 DUP 0.431818 0.887324
99 2GW 0.431373 0.901408
100 M7G 0.430108 0.780488
101 CNU 0.428571 0.927536
102 CDM 0.427083 0.842105
103 H6Y 0.425532 0.851351
104 16B 0.421687 0.888889
105 S5P 0.419753 0.915493
106 8GT 0.419355 0.855263
107 CXY 0.418367 0.888889
108 UPA 0.418182 0.842105
109 U2G 0.410714 0.822785
110 U A A U 0.409836 0.842105
111 UML 0.408759 0.810127
112 UP6 0.407407 0.871429
113 M7M 0.40625 0.771084
114 1GW 0.40367 0.864865
115 BMP 0.402439 0.970149
116 APU 0.401786 0.828947
117 PMP UD1 0.401575 0.7875
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 1YRO; Ligand: GDU; Similar sites found with APoc: 98
This union binding pocket(no: 1) in the query (biounit: 1yro.bio1) has 37 residues
No: Leader PDB Ligand Sequence Similarity
1 4K10 NI9 2.0979
2 6AIC AMP 2.33645
3 3FIU POP 2.81124
4 2J5S KTA 3.25203
5 2GDJ ANP 3.25203
6 1B3X XYP XYP XYP 3.84615
7 1R6N 434 4.06504
8 1H7F C5P 4.08163
9 3U2U UDP 4.18251
10 2V5K OXM 4.1958
11 5VCM UDP 4.54545
12 4B5W PYR 4.6875
13 4Z7X 3CX 4.87805
14 3A8H TAY 4.87805
15 1ZGS XMM 4.87805
16 4L4J NAG NAG BMA MAN NAG 4.87805
17 4MIX UD1 4.87805
18 5H62 UDP 4.87805
19 2CBZ ATP 5.06329
20 4PYA 2X3 5.59006
21 1W0J ADP 5.59441
22 5TZJ UD1 5.69106
23 3V91 UPG 5.69106
24 1GA8 UPF 5.69106
25 6BSW UDP 5.69106
26 1JI0 ATP 5.69106
27 5ZXD ATP 5.69106
28 2D7I UDP 5.94406
29 2D7I NGA 5.94406
30 4DW4 U5P 5.98802
31 1IUP ALQ 6.38298
32 2J0B UDP 6.42857
33 4WZ6 ATP 6.50407
34 3ITJ CIT 6.50407
35 3ZF8 GDP 6.50407
36 4LIK CIT 6.50407
37 4IKZ AFS 6.64336
38 1R0X ATP 6.64336
39 4FRZ ADP 6.64336
40 2VWT PYR 6.74157
41 5AJP UDP 6.99301
42 5NDF UDP 6.99301
43 5NDF LU2 6.99301
44 3CU0 UDP 7.31707
45 4AG5 ADP 7.31707
46 2XZ9 PYR 7.31707
47 1J6W MET 7.31707
48 1O7Q GAL NAG 7.34266
49 2BVL UDP 7.34266
50 2BVL GLC 7.34266
51 1O7Q UDP 7.34266
52 5J3R GSH 7.38916
53 1T5C ADP 7.69231
54 1XPJ TLA 7.93651
55 4WBD CIT 8.04196
56 5E5U MLI 8.13008
57 5FJJ MAN 8.13008
58 4KFU ACP 8.13008
59 6H0B UDP 8.13008
60 2PZE ATP 8.73362
61 2VL8 CTS 8.74126
62 2VL8 UDP 8.74126
63 1Q19 SSC 8.94309
64 4PPF FLC 8.94309
65 2J5V PCA 8.94309
66 6FXR UDP 8.94309
67 4PQG NAG 8.94309
68 3T5M AMP 9.44056
69 5A96 GTP 9.7561
70 3VMG 9CA 9.7561
71 1LL2 UPG 10.1399
72 3L6R MLI 10.5691
73 2VHJ ADP 10.5691
74 3K4Q IHS 10.5691
75 5LUN ARG 10.5691
76 4WNP 3RJ 11.1498
77 2VAR AMP 11.3821
78 4NTX AMR 11.3821
79 3KPE TM3 11.7647
80 1P7T PYR 12.1951
81 5HV7 RBL 12.1951
82 1D8C GLV 12.5874
83 5URY PAM 13.0137
84 3CBG FER 13.3621
85 2VMG MBG 13.3758
86 4OWK NGA 13.8211
87 1YID ATP 14.6341
88 1JJV ATP 15.0485
89 2WZG UPG 15.4472
90 1T0S BML 17.4419
91 4B1L FRU 18.6992
92 6E8I PTR 20.3252
93 2APC UDM 21.9512
94 2V7Q ATP 24
95 2VOH CIT 26.9231
96 1OMZ UD2 30.0813
97 2FFU UDP 38.4615
98 4IRP UDP 43.4263
Pocket No.: 2; Query (leader) PDB : 1YRO; Ligand: UDP; Similar sites found with APoc: 213
This union binding pocket(no: 2) in the query (biounit: 1yro.bio1) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 4WG0 CHD None
2 5OO5 UUA None
3 5J1J ANP 1.05263
4 3O9Z NAD 1.3986
5 3O9Z AKG 1.3986
6 2WBP ZZU 1.74825
7 2WBP SIN 1.74825
8 4GID 0GH 2.0979
9 4ZRB COA 2.18978
10 4IVN BMX 2.43902
11 6GBV FMN 2.73973
12 2O4J VD4 2.7972
13 5Y80 IRE 2.7972
14 4R4U COA 3.14685
15 4JNA FAD 3.25203
16 3Q60 ATP 3.25203
17 1IOW ADP 3.25203
18 1IOW PHY 3.25203
19 5DMZ ADP 3.25203
20 4CQE CQE 3.25203
21 5DEY 59T 3.4965
22 1PA9 CSN 3.52113
23 4JEM C5P 3.52941
24 2IU8 PLM 3.84615
25 6B3V ANP 4.06504
26 6B3V 7DQ 4.06504
27 3G5S FAD 4.06504
28 3QJ4 FAD 4.06504
29 1TV5 ORO 4.06504
30 5W4W 9WG 4.06504
31 3GF4 FAD 4.06504
32 4KBA 1QM 4.06504
33 2II3 CAO 4.06504
34 2WET FAD 4.06504
35 6C6O ENG 4.06504
36 4EHU ANP 4.06504
37 4CZG QH3 4.06504
38 4CZG ADP 4.06504
39 2Q09 DI6 4.06504
40 2YCH ATP 4.1958
41 1V1A KDG 4.1958
42 6FBZ MGP 4.5
43 2YAB AMP 4.54545
44 3CGB FAD 4.54545
45 4R57 ACO 4.54545
46 4A59 AMP 4.87805
47 4WVO 3UZ 4.87805
48 1F76 ORO 4.87805
49 2WQN ADP 4.87805
50 3ZYR ASN NAG NAG BMA MAN MAN NAG NAG 4.87805
51 5OBU ANP 4.87805
52 4L4J NAG NAG BMA MAN NAG 4.87805
53 2E2P ADP 4.87805
54 5GP0 GPP 4.87805
55 4MDH NAD 4.87805
56 1W0O DAN 4.8951
57 4X9M FAD 4.8951
58 3WHB DCC 5.15464
59 3D91 REM 5.24476
60 4C12 UML 5.24476
61 4C12 ADP 5.24476
62 1GR0 NAD 5.24476
63 3CH6 NAP 5.59441
64 3CH6 311 5.59441
65 5EOB 5QQ 5.69106
66 5U7W ADE 5.69106
67 5O3N 4LU 5.69106
68 2IXB NAD 5.69106
69 2IXB A2G 5.69106
70 1E8C UAG API 5.69106
71 5DBX ANP 5.69106
72 5TIV A3P 5.69106
73 1LUA NAP 5.69106
74 4BGB ADP 5.69106
75 5MJA 7O3 5.69106
76 2NXW TPP 5.69106
77 3ETG NDP 5.94406
78 3ETG GLU 5.94406
79 4RHP PEF 5.95745
80 4CSV STI 6.18182
81 5OBY ANP 6.29371
82 5J6A P46 6.29371
83 6GQM F8H 6.29371
84 3WQT ANP 6.50407
85 4A2A ATP 6.50407
86 4YZC STU 6.50407
87 4EUE NAI 6.50407
88 4A2B AGS 6.50407
89 4REL KMP 6.50407
90 3WBD SIA SIA SIA SIA SIA SIA SIA 6.50407
91 2RHQ GAX 6.50407
92 5GZ9 ANP 6.50407
93 2GQS ADP 6.50407
94 3KDU NKS 6.50407
95 2Y6O 1N1 6.50407
96 3KJS NAP 6.50407
97 4MWV BCZ 6.50407
98 3FG2 FAD 6.50407
99 2GQR ADP 6.50407
100 2XZI KDM 6.64336
101 2NPX FAD 6.64336
102 5T79 NDP 6.99301
103 5EOU ATP 7.31707
104 5JFS 6K0 7.31707
105 4TWP AXI 7.31707
106 2FR3 REA 7.31707
107 1A59 COA 7.31707
108 3I0O ADP 7.31707
109 3NJQ NJQ 7.31707
110 5A65 TPP 7.31707
111 3WXL ADP 7.31707
112 5VC5 96M 7.34266
113 6D6L FY4 7.64706
114 6APL C5P 7.69231
115 2OO8 RAJ 7.69231
116 4M20 COA 7.87402
117 1PG4 PRX 8.13008
118 1PG4 COA 8.13008
119 3IGO ANP 8.13008
120 4LNU GTP 8.13008
121 3HKW IX6 8.39161
122 4OH4 ANP 8.39161
123 3R1V AZB 8.66142
124 2YJ0 420 8.69565
125 2JDR L20 8.74126
126 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 8.74126
127 3E7O 35F 8.74126
128 3PP0 03Q 8.94309
129 3NTA FAD 8.94309
130 5X68 FAD 8.94309
131 6F97 FAD 8.94309
132 1Q19 APC 8.94309
133 5D63 FUC GAL GLA 8.94309
134 6F9Q NAD 8.94309
135 4ZW9 GLC 8.94309
136 4ZW9 BGC 8.94309
137 3VSV XYP 8.94309
138 5LY3 ADP 8.94309
139 4A62 ANP 9.44056
140 3L2B B4P 9.7561
141 6GNA FAD 9.7561
142 2B9W FAD 9.7561
143 4S15 4D8 9.7561
144 2Y6Q FAD 9.7561
145 5QIN J2V 9.7561
146 2ZGY GDP 9.79021
147 5MT9 SRO 10
148 1Q8Y ADP 10.1399
149 4CBU ATP 10.2362
150 5ITZ GTP 10.2362
151 1EU1 MGD 10.5691
152 3UIM ANP 10.5691
153 3OA2 NAD 10.5691
154 1XCL SAH 10.6383
155 6GH1 ARG LEU PRO ALA LYS ALA PRO LEU LEU 10.9489
156 3AAQ ARU 11.3821
157 5IH1 GDP 11.3821
158 5IH1 6BQ 11.3821
159 2ZB3 NDP 11.3821
160 6COJ F8G 11.3821
161 1MOQ GLP 11.3821
162 5DXT 5H5 11.3821
163 1OZH HE3 11.3821
164 3TIC ZMR 11.3821
165 4BR5 ANP 12.1951
166 5HV7 RBL 12.1951
167 1M13 HYF 12.1951
168 4JNE ATP 12.1951
169 4B9Q ATP 12.1951
170 3QKT ANP 12.1951
171 4BCM T7Z 12.1951
172 4MO2 FAD 12.1951
173 5ZM4 9FU 12.1951
174 2F9L GDP 12.1951
175 4CJX NAP 13.0081
176 1PS9 FAD 13.0081
177 5B48 TDN 13.0081
178 5EXW 7DT 13.2867
179 6EOF ADP 13.6364
180 4AMV F6R 13.6364
181 6ASY ATP 13.6364
182 6E08 NAP 13.8211
183 3D9F FAD 13.8211
184 3D9F N6C 13.8211
185 2C0U FAD NBT 13.8211
186 2R5T ANP 13.8211
187 2VBF TPP 14.6341
188 3EWK FAD 14.6341
189 1ZPD DPX 15.035
190 1F2U ATP 15.4362
191 4KVL PLM 15.4472
192 6BHQ NAG NAG FUL BMA MAN MAN NAG GAL 15.4472
193 6CGZ HL6 15.4472
194 6C7Y ADP 16.2393
195 3OZ2 OZ2 16.2602
196 4FE2 ADP 16.2602
197 6GWR FEW 16.2602
198 3VGL ANP 17.8862
199 1TQP ATP 17.8862
200 4P7X YCP 18.6992
201 4P7X AKG 18.6992
202 3SUD SUE 19.7044
203 1NRL SRL 20
204 2NVA PL2 23.5772
205 2ZSH GA3 24.3902
206 5NTW 98N 30
207 5K2M ADP 30.0813
208 1F9V ADP 30.8943
209 5NI5 8YB 33.3333
210 1N4H REA 33.3333
211 3EBL GA4 34.9594
212 6ESN BWE 41.6667
213 2P54 735 41.6667
Pocket No.: 3; Query (leader) PDB : 1YRO; Ligand: UDP; Similar sites found with APoc: 80
This union binding pocket(no: 3) in the query (biounit: 1yro.bio2) has 10 residues
No: Leader PDB Ligand Sequence Similarity
1 6CHP F0Y 2.48447
2 4JAL SAH 2.99401
3 3EKK GS2 3.14685
4 4BFM ANP 3.25203
5 4N9I PCG 3.33333
6 3EM0 CHD 3.62319
7 2J83 BAT 4.06504
8 3WQM B29 4.06504
9 3VHE 42Q 4.06504
10 4MZU TDR 4.1958
11 5L92 C0R 4.1958
12 4MZU COA 4.1958
13 2UYT ADP 4.1958
14 2UYT LRH 4.1958
15 3MQG ACO 4.6875
16 3MQG UDP 4.6875
17 3MQG UDP UDP 4.6875
18 5NII FAD 4.87805
19 3ZYR NAG NAG BMA MAN MAN NAG NAG 4.87805
20 3TDH AMP 5.02793
21 4OYA 1VE 5.69106
22 3PVW QRX 5.69106
23 3C1X CKK 5.69106
24 2QCS ANP 5.69106
25 4ZAC 4LU 5.69106
26 2QWO ADP 5.69106
27 4B1V ATP 5.69106
28 5YPU ATP 5.69106
29 5NWI TYR PHE SER SEP ASN 5.72519
30 1P7L SAM 6.50407
31 1P7L PPK 6.50407
32 1P7L ANP 6.50407
33 1P7L MET 6.50407
34 2UZH IPE 6.50407
35 2A40 ATP 6.50407
36 1USR DAN 6.50407
37 2A42 ATP 6.50407
38 1I00 D16 6.50407
39 1I00 UMP 6.50407
40 2WCV FUC 6.50407
41 3GL0 HXX 6.50407
42 2A3Z ATP 6.50407
43 4PKG ATP 6.98925
44 2HVW DDN 7.06522
45 1DMR PGD 7.31707
46 5LGD PLM 7.31707
47 5LI1 ANP 7.31707
48 1NVM NAD 7.31707
49 5LI9 ACP 7.31707
50 8CAT NDP 7.34266
51 5A6N U7E 7.42049
52 5LU5 M7P 7.61421
53 5EW9 5VC 8.13008
54 6A0S HSE 8.13008
55 6A0S NDP 8.13008
56 1KXP ATP 8.94309
57 3SJH ATP 9.25926
58 3SJH LAR 9.25926
59 3EWC MCF 9.79021
60 4KP7 1UQ 10.5691
61 5AR0 GB8 10.5691
62 2WU6 DKI 10.8392
63 5C1M CLR 11.2
64 1YZN GNP 11.3821
65 1WN3 HXC 11.7647
66 6ACS CIT 12.1951
67 4MO2 FDA 12.1951
68 5H3A D16 13.0081
69 5H3A UMP 13.0081
70 5V3Y 5V8 13.0081
71 6CI9 NAP 13.0081
72 5MZI FAD 14.6341
73 5MZI FYK 14.6341
74 4OIV XX9 14.6341
75 3VPC ADP 14.6341
76 5AE9 OKO 15.4472
77 4FHD EEM 15.4472
78 4FHD 0TT 15.4472
79 4LRJ ANP 21.1382
80 3UG4 AHR 25.2033
Pocket No.: 4; Query (leader) PDB : 1YRO; Ligand: GDU; Similar sites found with APoc: 41
This union binding pocket(no: 4) in the query (biounit: 1yro.bio2) has 38 residues
No: Leader PDB Ligand Sequence Similarity
1 2D2F ADP 2.43902
2 5LQ8 GB 2.48227
3 1HPG BOC ALA ALA PRO GLU 3.25203
4 3K8D KDO 4.06504
5 5WS9 ATP 4.1958
6 1OXV ANP 4.54545
7 5XQL C2E 4.87805
8 4YRD 3IT 4.87805
9 3CV2 OXL 4.87805
10 2OVW CBI 5.69106
11 4G7A AZM 5.69106
12 4X5S AZM 5.69106
13 3W21 AKG 5.69106
14 2FSH ANP 5.69106
15 5O6Y 5YA 5.69106
16 1V84 UDP 5.92885
17 4U00 ADP 6.55738
18 4LYA ATP 6.64336
19 4L80 OXL 6.99301
20 1LAN LEU 7.31707
21 2VVG ADP 7.31707
22 1KKR 2AS 7.31707
23 4DE3 DN8 8.13008
24 1G6H ADP 8.13008
25 3A4M ADP 8.13008
26 1JJ7 ADP 8.94309
27 1IZC PYR 8.94309
28 1KC7 PPR 9.7561
29 5Z49 RUB 9.7561
30 3IUY AMP 9.7561
31 1GXU 2HP 10.989
32 1YQT ADP 11.1888
33 3T3Z 9PL 11.5385
34 2KIN ADP 12.1951
35 5UFC DR2 12.1951
36 2AWN ADP 12.5874
37 4TX6 38B 13.0081
38 4KVL PLM 15.4472
39 4COQ SAN 16.2602
40 3B9Q MLI 18.6992
41 2OG2 MLI 18.6992
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