Receptor
PDB id Resolution Class Description Source Keywords
2GCO 1.4 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE HUMAN RHOC-GPPNHP COMPLEX HOMO SAPIENS GTP-BINDING PROTEIN GTPASESIGNALING PROTEIN SIGNALING PRO
Ref.: X-RAY CRYSTAL STRUCTURES REVEAL TWO ACTIVATED STATE RHOC. BIOCHEMISTRY V. 46 6547 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GNP A:1001;
B:1003;
Valid;
Valid;
none;
none;
submit data
522.196 C10 H17 N6 O13 P3 c1nc2...
MG A:1002;
B:1004;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2GCO 1.4 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE HUMAN RHOC-GPPNHP COMPLEX HOMO SAPIENS GTP-BINDING PROTEIN GTPASESIGNALING PROTEIN SIGNALING PRO
Ref.: X-RAY CRYSTAL STRUCTURES REVEAL TWO ACTIVATED STATE RHOC. BIOCHEMISTRY V. 46 6547 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 2GCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 4XSG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
2 3LXR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3LWN - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 3LW8 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 2GCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 1CXZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
7 4D0N - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 171 families.
1 1HE1 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4XSG - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
3 2GCO - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
4 1CXZ - GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
5 4YC7 - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
6 4D0N - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GNP; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 GNP 1 1
2 GDP 0.839506 0.973684
3 GP3 0.82716 0.948718
4 GTP 0.809524 0.973684
5 GNH 0.807229 0.986842
6 G1R 0.77907 0.961039
7 GCP 0.77907 0.948718
8 GSP 0.770115 0.925
9 5GP 0.756098 0.960526
10 G 0.756098 0.960526
11 G2R 0.747253 0.936709
12 GMV 0.747126 0.948718
13 GAV 0.714286 0.936709
14 GP2 0.712644 0.936709
15 G2P 0.711111 0.936709
16 Y9Z 0.708333 0.880952
17 GDP MG 0.696629 0.9
18 GDD 0.690722 0.936709
19 GDC 0.690722 0.936709
20 GKE 0.690722 0.936709
21 GDP BEF 0.688889 0.878049
22 G5P 0.686869 0.948718
23 GPG 0.684211 0.936709
24 GTG 0.683673 0.91358
25 GFB 0.683673 0.936709
26 GDR 0.683673 0.936709
27 JB2 0.68 0.936709
28 GKD 0.68 0.936709
29 G3A 0.676768 0.948718
30 6CK 0.676768 0.91358
31 GDX 0.673267 0.948718
32 ALF 5GP 0.67033 0.86747
33 GTP MG 0.666667 0.9
34 BEF GDP 0.666667 0.86747
35 YGP 0.663265 0.879518
36 GCP G 0.659574 0.911392
37 GPD 0.656863 0.902439
38 GDP AF3 0.645833 0.86747
39 GDP ALF 0.645833 0.86747
40 JB3 0.641509 0.925
41 DBG 0.640351 0.974359
42 G3D 0.638298 0.960526
43 G4P 0.625 0.960526
44 GMP 0.621951 0.857143
45 NGD 0.62037 0.936709
46 GGM 0.618182 0.925926
47 0O2 0.616162 0.960526
48 G G 0.61 0.911392
49 2MD 0.603604 0.870588
50 CAG 0.60177 0.904762
51 U2G 0.590909 0.91358
52 FEG 0.590909 0.858824
53 GDP 7MG 0.590476 0.888889
54 MGD 0.587719 0.870588
55 ZGP 0.585586 0.848837
56 CG2 0.580357 0.91358
57 ANP 0.568421 0.922078
58 PGD 0.567797 0.902439
59 MD1 0.567797 0.870588
60 3GP 0.56044 0.922078
61 TPG 0.558333 0.822222
62 GH3 0.55 0.948052
63 FE9 0.546219 0.778947
64 GPX 0.539216 0.922078
65 G4M 0.539062 0.860465
66 DGI 0.536082 0.9
67 BGO 0.535088 0.901235
68 IDP 0.53125 0.947368
69 DGT 0.53 0.9
70 2GP 0.526882 0.935065
71 G1R G1R 0.520325 0.901235
72 I2C FE2 CMO CMO 0.516667 0.811111
73 U A G G 0.512605 0.911392
74 AGO 0.504202 0.91358
75 G A A A 0.504202 0.9
76 P2G 0.5 0.860759
77 G1G 0.5 0.902439
78 MGP 0.49505 0.936709
79 PGD O 0.492063 0.831461
80 6G0 0.490196 0.936709
81 P1G 0.489796 0.85
82 DGP 0.474227 0.8875
83 DG 0.474227 0.8875
84 G G U 0.473684 0.911392
85 IMP 0.463918 0.934211
86 G2Q 0.462963 0.936709
87 GPC 0.459677 0.858824
88 G C 0.459016 0.878049
89 GTA 0.448276 0.91358
90 G7M 0.444444 0.924051
91 MAP 0.439252 0.898734
92 G G G RPC 0.435484 0.853659
93 B4P 0.434343 0.871795
94 AP5 0.434343 0.871795
95 ADP 0.434343 0.896104
96 A2D 0.43299 0.871795
97 U G A 0.431655 0.86747
98 G G G C 0.426357 0.890244
99 SGP 0.425743 0.807229
100 AU1 0.425743 0.922078
101 BA3 0.424242 0.871795
102 35G 0.423077 0.909091
103 PCG 0.423077 0.909091
104 A G C C 0.423077 0.888889
105 C2E 0.423077 0.897436
106 APC G U 0.421875 0.864198
107 ATP 0.421569 0.896104
108 ACQ 0.419048 0.873418
109 5GP 5GP 0.419048 0.860759
110 AQP 0.417476 0.896104
111 5FA 0.417476 0.896104
112 01G 0.417391 0.880952
113 UNP 0.415842 0.810127
114 AN2 0.415842 0.909091
115 6AD 0.415094 0.821429
116 ITT 0.411765 0.846154
117 M33 0.411765 0.860759
118 G C C C 0.410448 0.901235
119 G U34 0.408 0.86747
120 ACP 0.407767 0.873418
121 APR 0.403846 0.871795
122 AR6 0.403846 0.871795
123 DG DG 0.403509 0.845238
124 A4P 0.403226 0.848837
125 UCG 0.402985 0.888889
126 AD9 0.4 0.873418
127 SAP 0.4 0.851852
128 AGS 0.4 0.851852
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2GCO; Ligand: GNP; Similar sites found: 436
This union binding pocket(no: 1) in the query (biounit: 2gco.bio2) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5MZN ADP 0.001714 0.45775 1.49254
2 4WEI GLC GAL 0.01154 0.42091 1.49254
3 3R7F CP 0.01123 0.41946 1.49254
4 3MD0 GDP 0.00000002043 0.69403 1.99005
5 1F9V ADP 0.000003228 0.4708 1.99005
6 4RZ3 ADP 0.0008753 0.44105 1.99005
7 1VHT BA3 0.001402 0.441 1.99005
8 2XT3 ADP 0.000001236 0.63072 2.48756
9 1D2E GDP 0.00000006675 0.6291 2.48756
10 3LRE ADP 0.000002372 0.61807 2.48756
11 4PPF FLC 0.000004898 0.60364 2.48756
12 2ZR9 DTP 0.000153 0.497 2.48756
13 2BEK ATP 0.0002057 0.44288 2.48756
14 4IHQ ADP 0.0001068 0.43837 2.48756
15 4P32 ADP 0.001405 0.40798 2.48756
16 3ZS9 ADP ALF 0.00003608 0.44226 2.54237
17 2WOJ ADP ALF 0.00004003 0.4409 2.54237
18 3TK1 GDP 0.00000004054 0.69127 2.98507
19 1T5C ADP 0.0000007606 0.64958 2.98507
20 4LC1 GDP 0.00000012 0.64574 2.98507
21 1TQ4 GDP 0.0000003612 0.56238 2.98507
22 3E70 GDP 0.00004846 0.5141 2.98507
23 3BFV ADP 0.000144 0.49826 2.98507
24 4ZNL BEF ADP 0.0001347 0.49335 2.98507
25 4V03 ADP 0.0002172 0.47795 2.98507
26 2OZE AGS 0.0001086 0.47141 2.98507
27 2VVG ADP 0.0000003886 0.46774 2.98507
28 4D81 ADP 0.0003609 0.46272 2.98507
29 5X40 ACP 0.001234 0.44265 2.98507
30 2CHG ANP 0.0008342 0.44196 2.98507
31 5K5Z ANP 0.00009729 0.44165 2.98507
32 1IN4 ADP 0.0007291 0.43569 2.98507
33 1DNP MHF 0.009243 0.4281 2.98507
34 2C9O ADP 0.0008028 0.42558 2.98507
35 3L6C MLI 0.01003 0.4238 2.98507
36 1G6O ADP 0.0002023 0.47936 3.0303
37 1SVI GDP 0.000000001455 0.75042 3.07692
38 1V8K ANP 0.000003897 0.57334 3.48259
39 5I0H ADP BEF 0.000002711 0.55609 3.48259
40 1JJV ATP 0.00007377 0.53195 3.48259
41 1YQT ADP 0.0000974 0.52665 3.48259
42 4E03 ADP 0.00007211 0.50603 3.48259
43 3FKQ ATP 0.00006232 0.49106 3.48259
44 2GDJ ANP 0.0002179 0.48965 3.48259
45 5G41 AP5 0.003675 0.44676 3.48259
46 3EWA ANP 0.0001178 0.44375 3.48259
47 1UKZ ADP 0.003058 0.43847 3.48259
48 4QRH 0O2 0.00217 0.42795 3.48259
49 1D2N ANP 0.001726 0.41345 3.48259
50 3UIE ANP 0.00004978 0.50714 3.5
51 5H4I 7HQ 0.01298 0.40207 3.77358
52 3KTA AP5 0.0006337 0.45182 3.84615
53 2C77 GNP 0.0000000002813 0.73188 3.9801
54 2WIC GNP 0.00000001783 0.67455 3.9801
55 2FH5 GTP 0.0000000006316 0.67231 3.9801
56 2C78 GNP 0.0000000004004 0.66367 3.9801
57 2W58 ADP 0.000001432 0.63889 3.9801
58 5L3V GDP 0.00004007 0.51144 3.9801
59 4ZG4 VO4 ADP 0.00000268 0.50302 3.9801
60 1H65 GDP 0.000009899 0.4938 3.9801
61 5LTJ ADP 0.0001521 0.49089 3.9801
62 3Q9L ATP 0.00007826 0.48675 3.9801
63 1G3Q ADP 0.0003206 0.47576 3.9801
64 5FTB ANP 0.0002499 0.47517 3.9801
65 1ION ADP 0.0002666 0.47389 3.9801
66 2FAH GDP 0.0002339 0.47112 3.9801
67 5LTJ BEF 0.002035 0.46623 3.9801
68 3P4X ADP 0.00004677 0.45603 3.9801
69 3VX3 ADP 0.0004359 0.44626 3.9801
70 5FHD ADP ALF 0.0003225 0.44121 3.9801
71 3ZQ6 ADP ALF 0.00004375 0.43932 3.9801
72 3BER AMP 0.01124 0.40752 3.9801
73 4GLL NAD 0.01635 0.40451 3.9801
74 1LVG ADP 0.00002 0.45188 4.0404
75 2BVN GNP 0.0000000002871 0.73457 4.47761
76 3U6B GDP 0.000000005253 0.72302 4.47761
77 3U6K GDP 0.00000001074 0.69594 4.47761
78 5JBQ GDP 0.00000001445 0.68977 4.47761
79 4G5G GDP 0.00000001524 0.68866 4.47761
80 3A1S GDP 0.0000001523 0.63102 4.47761
81 4PC3 GDP 0.000000289 0.60074 4.47761
82 1D8T GDP 0.00000001711 0.59618 4.47761
83 4P3Y GDP 0.00000001039 0.59165 4.47761
84 2NCD ADP 0.000005401 0.59097 4.47761
85 4ZKD GDP 0.000000001762 0.58768 4.47761
86 2OG2 MLI 0.0001162 0.52967 4.47761
87 3B9Q MLI 0.0002499 0.50942 4.47761
88 3BOS CDP 0.00008545 0.50912 4.47761
89 5L3W GDP 0.00005299 0.5059 4.47761
90 1R6B ADP 0.0002322 0.48231 4.47761
91 2KIN ADP 0.0000002642 0.47128 4.47761
92 5L3S GNP 0.00001665 0.4674 4.47761
93 5XDR ADP 0.0007377 0.45884 4.47761
94 2ZPA ADP 0.0005527 0.45202 4.47761
95 1FNN ADP 0.0004153 0.4461 4.47761
96 2FNA ADP 0.0005255 0.42517 4.47761
97 5L3S G 0.01383 0.41694 4.47761
98 1K6M AGS 0.000613 0.41567 4.47761
99 1XX6 ADP 0.0005504 0.41653 4.71204
100 1U0J ADP 0.0009391 0.4649 4.86891
101 1SKQ GDP 0.00000002572 0.68911 4.97512
102 4M9Q GNP 0.000000001843 0.63974 4.97512
103 1G7S GDP 0.000000171 0.62867 4.97512
104 2HCJ GDP 0.000000002833 0.60952 4.97512
105 4NON GDP 0.00000001834 0.5415 4.97512
106 3ZFD ANP 0.000002575 0.53216 4.97512
107 4YMU ATP 0.00005559 0.52524 4.97512
108 2IYL GDP 0.00004188 0.52395 4.97512
109 4HSE ADP 0.00003591 0.52018 4.97512
110 3EZ2 ADP 0.00008676 0.51574 4.97512
111 2DPY ADP 0.000135 0.51347 4.97512
112 1SQ5 ADP 0.00007113 0.50631 4.97512
113 4KFU ACP 0.000004944 0.46749 4.97512
114 4XGU ADP 0.0004568 0.45336 4.97512
115 1IHU AF3 0.0001516 0.44642 4.97512
116 5VGR GDP 0.0007847 0.44312 4.97512
117 1IHU ADP 0.0001631 0.4373 4.97512
118 5M7P ADP 0.0008535 0.43278 4.97512
119 2XAU ADP 0.0008673 0.42755 4.97512
120 4OI4 ATP 0.000723 0.4128 4.97512
121 2J5V PCA 0.04025 0.40211 4.97512
122 4BQS ADP 0.00009549 0.50681 5.11364
123 2XTN GTP 0.00001583 0.47799 5.12821
124 1W7J ADP BEF 0.0002564 0.46429 5.29801
125 3CNL GNP 0.00000009498 0.66124 5.47264
126 4R98 GNH 0.0000004027 0.62055 5.47264
127 3B5J 12D 0.00003592 0.5425 5.47264
128 2QEN ADP 0.00009722 0.48265 5.47264
129 5HR5 ADP 0.0003989 0.45593 5.47264
130 4MKG AP5 0.002513 0.44956 5.47264
131 1OE0 TTP 0.007959 0.41114 5.47264
132 1W5T ANP 0.002144 0.40912 5.47264
133 1W5T ADP 0.004816 0.40874 5.47264
134 1XPJ TLA 0.02274 0.4172 5.55556
135 1APZ ASP 0.01944 0.40431 5.67376
136 1DCP HBI 0.02655 0.40833 5.76923
137 4CVN ADP 0.00001203 0.56647 5.83942
138 5IRR GSP 0.00000004144 0.58529 5.97015
139 2WHX ADP 0.00003407 0.5509 5.97015
140 2BIF ANP 0.0004133 0.47888 5.97015
141 2BIF SIN 0.0007145 0.47888 5.97015
142 2VF7 ADP 0.0007876 0.45752 5.97015
143 2CE7 ADP 0.0001703 0.45617 5.97015
144 3DKP ADP 0.001143 0.45516 5.97015
145 1RRC ADP 0.00001404 0.43148 5.97015
146 3BFX A3P 0.005346 0.40096 5.97015
147 5H56 ADP 0.001004 0.45668 6.15385
148 5H56 TYD 0.001004 0.45668 6.15385
149 3W5J GDP 0.000002248 0.61788 6.46766
150 1WDT GTP 0.000000131 0.59362 6.46766
151 1JI0 ATP 0.00004141 0.53938 6.46766
152 4PFO ADP 0.0001087 0.49378 6.46766
153 1G41 ADP 0.0002655 0.47398 6.46766
154 2JLR ANP 0.000277 0.46785 6.46766
155 1NJF AGS 0.0005269 0.45716 6.46766
156 1NJF ADP 0.0005331 0.45271 6.46766
157 1OFH ADP 0.0002985 0.44679 6.46766
158 2IXE ATP 0.0006121 0.42245 6.46766
159 4A4Z ANP 0.006337 0.41948 6.46766
160 4YS0 ADP 0.003379 0.41546 6.46766
161 3CV2 OXL 0.02816 0.40528 6.46766
162 1BO4 COA 0.009002 0.41215 6.54762
163 2ZFI ADP 0.00000495 0.56837 6.55738
164 3IIJ ADP 0.00004369 0.52307 6.66667
165 5MVR ADP 0.00004805 0.52109 6.79012
166 3DC4 ADP 0.000002969 0.59715 6.96517
167 1TAD GDP 0.000000007939 0.55199 6.96517
168 1TAD ALF 0.000000007939 0.55199 6.96517
169 5N69 ADP 0.0001377 0.48138 6.96517
170 5I34 GDP 0.0008396 0.45622 6.96517
171 4IDN GNP 0.0001578 0.44575 6.96517
172 3FVQ ATP 0.0005797 0.43084 6.96517
173 2ZJ5 ADP 0.006877 0.43041 6.96517
174 4QM7 GTP 0.0001099 0.50389 7.01754
175 2PEZ DAT 0.000486 0.47417 7.26257
176 2WJG GDP 0.00000001443 0.68979 7.44681
177 2QN6 GDP 0.000000002254 0.74108 7.46269
178 3VMF GTP 0.000000002587 0.70225 7.46269
179 4RD0 GDP 0.0000000002538 0.67105 7.46269
180 2CBZ ATP 0.0000006686 0.65951 7.46269
181 3IO3 ADP 0.000153 0.47648 7.46269
182 4QOS ADP 0.0003358 0.46932 7.46269
183 2Y65 ADP 0.000001654 0.46646 7.46269
184 2GK6 ADP 0.001709 0.45781 7.46269
185 3KJI ADP 0.0006879 0.43984 7.46269
186 1P9B GDP 0.00389 0.41279 7.46269
187 4KVA GTP 0.000002493 0.40618 7.46269
188 4H1V GNP 0.000005851 0.53583 7.9602
189 5GJC ATP 0.00004529 0.52232 7.9602
190 3ZIA ATP 0.0000358 0.52024 7.9602
191 3ZIA ADP 0.00009252 0.48907 7.9602
192 5IFS ADP 0.0002861 0.44703 7.9602
193 1OXV ANP 0.00005636 0.4445 7.9602
194 3RC3 ANP 0.006141 0.42477 7.9602
195 4XVU ATP 0.0001162 0.44462 8.26087
196 3EC1 GDP 0.0000002706 0.56413 8.40108
197 2HF9 GSP 0.0000001431 0.60607 8.45771
198 1G6H ADP 0.000005746 0.60531 8.45771
199 4AG5 ADP 0.00002824 0.55446 8.45771
200 2V7Q ADP 0.00005341 0.51889 8.45771
201 2V7Q ATP 0.00003625 0.51342 8.45771
202 2PL3 ADP 0.0003552 0.48566 8.45771
203 1M7G ADX 0.000263 0.48498 8.45771
204 1W0J ADP 0.00006498 0.48195 8.45771
205 1M7G ADP 0.0002644 0.48166 8.45771
206 1M7G AV2 0.0000158 0.46746 8.45771
207 1W0J ADP BEF 0.0003041 0.4634 8.45771
208 1XKV ATP 0.0006602 0.45592 8.45771
209 2CK3 ANP 0.0003114 0.45138 8.45771
210 1YTM ATP 0.0003046 0.44445 8.45771
211 2CK3 ADP 0.0002818 0.42903 8.45771
212 4U00 ADP 0.000007074 0.60092 8.95522
213 4WZA ACP 0.00001071 0.58337 8.95522
214 4WZA ADP 0.00001071 0.58337 8.95522
215 5LB3 ADP 0.00007571 0.51865 8.95522
216 1FP6 ADP 0.00008888 0.48985 8.95522
217 1Z6T ADP 0.0001529 0.47408 8.95522
218 3DZD ADP 0.000574 0.45374 8.95522
219 2WJH GDP 0.00000001339 0.61743 9.03614
220 2WJH FLC 0.000002376 0.53477 9.03614
221 3DEF GDP 0.000006931 0.53923 9.16031
222 4PX9 ADP 0.0004534 0.48045 9.45274
223 3B7G ANP 0.0004024 0.47115 9.45274
224 1BG2 ADP 0.000000336 0.46863 9.45274
225 3FB4 AP5 0.003083 0.44535 9.45274
226 1DAR GDP 0.0000001181 0.64607 9.95025
227 5GVR LMR 0.0003657 0.49485 9.95025
228 3T34 GDP 0.00005556 0.45897 9.95025
229 2ZE7 DST 0.009799 0.40703 9.95025
230 2ZE7 AMP 0.009207 0.40677 9.95025
231 2ZTS ADP 0.001051 0.42855 10.3586
232 3WY9 GDP 0.000000004481 0.72641 10.4478
233 3WXM GTP 0.000000001645 0.71111 10.4478
234 3WYA GDP 0.000000007144 0.70441 10.4478
235 4LPS GDP 0.00000003153 0.66298 10.4478
236 3FWY ADP 0.00007125 0.48853 10.4478
237 1OYY AGS 0.00116 0.45485 10.4478
238 2PZE ATP 0.000006549 0.44034 10.4478
239 1R0X ATP 0.000262 0.42475 10.4478
240 4XTR ADP 0.0001579 0.46385 10.8108
241 4XTR ATP 0.000108 0.44568 10.8108
242 5GOE GDP 0.0000003152 0.60742 10.9453
243 4LYA ATP 0.00004393 0.51609 10.9453
244 4R43 GDP 0.0001516 0.4972 10.9453
245 2Q2Y ADP 0.0002631 0.49607 10.9453
246 2Q2Y MKR 0.0002801 0.49352 10.9453
247 4IEE AGS 0.0008532 0.46695 10.9453
248 4Y4V DAL 0.004587 0.43505 10.9453
249 5E5U MLI 0.00508 0.431 11.0553
250 1G7C 5GP 0.000001328 0.59573 11.4428
251 1JWY GDP 0.000004216 0.54886 11.4428
252 1JWY ADP 0.00009508 0.50042 11.4428
253 1B0U ATP 0.001191 0.43961 11.4428
254 4J0Q GDP 0.0000000114 0.70648 11.9403
255 4YDS ATP 0.00001885 0.55663 11.9403
256 2IS6 ADP 0.0001837 0.49319 11.9403
257 2B8W ALF 5GP 0.00001316 0.4704 11.9403
258 3COB ADP 0.000002286 0.46264 11.9403
259 1F5N GNP 0.00001053 0.45758 11.9403
260 1NY5 ADP 0.0005516 0.44979 11.9403
261 2X7I CIT 0.004056 0.42879 11.9403
262 2ZPT A3P 0.04241 0.40117 11.9403
263 4MKF AP5 0.003071 0.44649 11.9816
264 2OBM ADP 0.0002993 0.50441 12.4378
265 5L3R GCP 0.000004509 0.49067 12.4378
266 1B7T ADP 0.0003398 0.46908 12.4378
267 1KK8 BEF ADP 0.0003739 0.45715 12.4378
268 4WOP CTP 0.00003753 0.48072 12.4444
269 2AWN ADP 0.0000008821 0.65603 12.9353
270 4WZ6 ATP 0.00002585 0.55738 12.9353
271 3RLF ANP 0.0006098 0.41517 12.9353
272 4R2I ANP 0.0009837 0.46993 13.4328
273 3TBK ANP 0.001075 0.46797 13.4328
274 4FCW ADP 0.0009082 0.42296 13.4328
275 5CK5 GDP 0.00000006212 0.6703 13.9303
276 2D2F ADP 0.000327 0.50443 13.9303
277 1KO8 6PG 0.001126 0.43847 14.2857
278 5TSH ADP 0.00006838 0.53344 14.4279
279 5TSH ANP 0.00003797 0.52599 14.4279
280 1WF3 GNP 0.000000006125 0.6882 14.9254
281 5M04 GDP 0.00000009652 0.66089 14.9254
282 2XTZ GSP 0.00000000377 0.59258 14.9254
283 1CR1 TTP 0.0004561 0.45786 14.9254
284 1ZCB GDP 0.000003556 0.56076 15.4229
285 2RCN GDP 0.000000001954 0.73138 15.9204
286 1KK1 GNP 0.0000000293 0.68634 15.9204
287 4OHY ANP 0.00004634 0.45334 16.4179
288 3A4M ADP 0.00001155 0.56738 16.5385
289 5J1J ANP 0.00007979 0.44976 16.9154
290 3ITJ CIT 0.01885 0.40956 16.9154
291 1PUJ GNP 0.000000003896 0.66133 17.4129
292 1NRJ GTP 0.0000000636 0.59443 17.4312
293 2VB6 ADP BEF 0.0003566 0.42433 17.4497
294 1GXU 2HP 0.0002704 0.48965 17.5824
295 1HTW ADP 0.00002836 0.47992 18.3544
296 2OFW ADX 0.0005677 0.47902 18.9055
297 1SVK ALF GDP 0.00000001338 0.68052 19.403
298 1JJ7 ADP 0.000003547 0.619 19.403
299 1BH2 GSP 0.00000003187 0.53349 19.403
300 2OM2 GDP 0.000004252 0.52091 19.403
301 1Y3A GDP 0.00000472 0.50081 19.403
302 1GP2 GDP 0.000006238 0.49702 19.403
303 2C04 GCP 0.0005859 0.44865 19.403
304 1CS4 GSP 0.000000006014 0.56514 19.9005
305 1AZT GSP 0.000000004046 0.55951 19.9005
306 4LJ9 ACP 0.002758 0.43683 20.398
307 1GOJ ADP 0.000000402 0.66339 20.8955
308 4NCN GTP 0.0000000001517 0.66314 20.8955
309 4TMZ GSP 0.0000000001558 0.66293 20.8955
310 4HI0 GDP 0.000004434 0.52016 20.8955
311 5H67 ATP 0.006263 0.41539 21.25
312 1ZJ6 G3D 0.00000006547 0.64815 22.4599
313 2VOH CIT 0.005463 0.43349 23.0769
314 4BAS GNP 0.00000001284 0.66191 23.1156
315 4TTQ ATP 0.0002144 0.48998 23.7209
316 1MR3 G3D 0.0000002133 0.56801 24.3094
317 2X77 GDP 0.000000008249 0.69019 24.3386
318 5KUT GDP 0.00000001047 0.61768 24.3386
319 3AQ4 GDP 0.0000001513 0.63116 25
320 5EE5 GTP 0.0000000005155 0.65996 25.731
321 3DOE GTP 0.0000000006771 0.64171 25.8706
322 5IRN ADP 0.0001281 0.48277 25.8706
323 1F6B GDP 0.0000009909 0.59302 26.2626
324 5KSZ GCP 0.0000000167 0.66562 26.3682
325 2D7D ADP 0.002516 0.4004 27.5
326 1J2J GTP 0.0000000005669 0.64357 27.8607
327 2J59 GTP 0.000000001172 0.63185 27.8607
328 1O3Y GTP 0.000000002706 0.62073 27.8607
329 5KSP GDP 0.000000007135 0.69313 27.8947
330 1KSH GDP 0.0000000007531 0.71301 27.957
331 1UPT GTP 0.00000000159 0.64065 28.3333
332 5HCN GCP 0.00000003192 0.66273 28.3582
333 1S9D GDP 0.0000004325 0.60985 28.3582
334 1RE0 GDP 0.00000005764 0.56729 28.3582
335 1GOT GDP 0.000006138 0.50462 28.3582
336 3H86 AP5 0.001797 0.45051 28.6458
337 5FG3 GDP 0.000000003502 0.60895 28.8557
338 2A5F GTP 0.000000001947 0.6123 29.7143
339 2QTV GNP 0.000000009536 0.6738 29.9401
340 1FQJ ALF 0.0000004096 0.65062 30.3483
341 1FQK ALF 0.000002122 0.62305 30.3483
342 1FQJ GDP 0.000001918 0.51448 30.3483
343 1FQK GDP 0.000006269 0.4969 30.3483
344 2GJ8 ALF GDP 0.000000005733 0.57066 30.814
345 3GJX GTP 0.000000000027 0.79492 31.3433
346 4KAX GTP 0.000000001642 0.70155 31.3609
347 3PCR GTP 0.000000005976 0.60861 31.4815
348 3M1I GTP 0.00000000002637 0.79539 31.8408
349 3WYF GTP 0.00000000004657 0.78737 31.8408
350 5BXQ GDP 0.000000002697 0.71287 31.8408
351 3CH5 GDP 0.00000000596 0.69678 31.8408
352 1IBR GNP 0.0000000000166 0.65571 31.8408
353 4HAT GNP 0.00000000001452 0.64324 31.8408
354 3N5C GDP 0.00000007139 0.65653 32.0988
355 2W83 GTP 0.000000001483 0.6293 32.1212
356 4YLG GDP 0.0000001378 0.60677 32.948
357 1R4A GNP 0.000000003543 0.60037 33.3333
358 3GJ4 GDP 0.00000000317 0.72131 33.8308
359 3GJ7 GDP 0.000000003484 0.71935 33.8308
360 3GJ8 GDP 0.000000002601 0.7136 33.8308
361 3GJ5 GDP 0.000000003012 0.71063 33.8308
362 2QZ4 ADP 0.0001201 0.48969 33.8308
363 2ZEJ GDP 0.000001442 0.49232 34.2391
364 3GJ0 GDP 0.000000004449 0.71426 34.3284
365 3GJ3 GDP 0.000000005845 0.6166 34.3284
366 3WYG GTP 0.00000000005933 0.62647 35.1648
367 4B47 GDP 0.000000007961 0.71414 35.3234
368 1Y63 ADP 0.00009696 0.50649 35.3234
369 4V0K GDP 0.0000006408 0.52076 35.503
370 1M2O GNP 0.000000003282 0.69758 36.3158
371 2G77 GDP 0.000000001246 0.69584 36.3636
372 1WA5 GTP 0.00000000002165 0.60316 36.3636
373 2G77 AF3 0.000004167 0.59832 36.3636
374 5UWT GNP 0.00000000001518 0.80626 36.8159
375 5DIF GNP 0.00000000000897 0.66327 36.8159
376 5UWU GNP 0.000000000009642 0.66169 36.8159
377 5UWI GNP 0.00000000001118 0.6604 36.8159
378 5UWJ GNP 0.00000000001148 0.6597 36.8159
379 5UWW GNP 0.00000000001289 0.65822 36.8159
380 5UWR GNP 0.00000000001354 0.65764 36.8159
381 5UWQ GNP 0.00000000001456 0.65689 36.8159
382 5DHF GNP 0.00000000001496 0.65637 36.8159
383 5UWH GNP 0.00000000001613 0.65558 36.8159
384 5UWP GNP 0.00000000001173 0.64621 36.8159
385 5DI9 GNP 0.00000000001497 0.64269 36.8159
386 5UWS GNP 0.00000000002072 0.63904 36.8159
387 3E5H GNP 0.000000001522 0.60423 38.764
388 3BC1 GNP 0.00000000005413 0.64978 38.9744
389 1Z06 GNP 0.000000000009967 0.69338 39.6825
390 2BCG GDP 0.000000001461 0.67393 39.801
391 1YZG GDP 0.0000001035 0.58086 40.2235
392 3CPJ GDP 0.000000009576 0.64509 40.2985
393 3T12 GDP ALF 0.000000002406 0.63718 40.2985
394 3T1O GDP 0.0000002676 0.5751 40.2985
395 1ZD9 GDP 0.00000004165 0.61424 41.791
396 4ZI2 GNP 0.0000000005099 0.66029 42.1053
397 3Q72 GNP 0.0000000001696 0.65118 42.1687
398 1VG8 GNP 0.00000000003873 0.78783 42.2886
399 1VG0 GDP 0.000000001602 0.67758 42.2886
400 4GOJ GNP 0.000000000876 0.71366 42.328
401 5DI3 GNP 0.000000008064 0.61607 42.7027
402 5SZH GNP 0.000000000003737 0.67411 42.7861
403 2BME GNP 0.000000000001279 0.85131 43.5484
404 2F9L GDP 0.000000002297 0.61894 43.7186
405 3TKL GTP 0.000000000003493 0.70674 43.8776
406 1OIX GDP 0.0000000001523 0.63543 43.9791
407 1FZQ GDP 0.00000003728 0.67005 44.1989
408 4DKX GDP 0.0000000001273 0.78819 44.2786
409 1OIV GDP 0.0000000018 0.70935 44.5026
410 3SFV GDP 0.000000007081 0.67007 44.7514
411 5UWO GNP 0.00000000001421 0.65753 45
412 1VG9 GDP 0.0000000003468 0.67646 45.9459
413 1VG1 GDP 0.0000000009056 0.66008 45.9459
414 2A9K GDP 0.0000000006438 0.70833 45.9893
415 1X1R GDP 0.0000000001546 0.62121 46.0674
416 1Z0F GDP 0.0000000001011 0.7795 46.3687
417 4D0G GTP 0.0000000001468 0.68083 46.8571
418 1YZN GNP 0.00000000001268 0.65823 47.027
419 4DSU GDP 0.0000000001304 0.62345 47.0899
420 1S8F GDP 0.000000000006955 0.6561 47.4576
421 5JCZ GDP 0.00000001733 0.62854 47.486
422 1Z0K GTP 0.000000000002564 0.72848 47.6744
423 1TU3 GNP 0.000000000001599 0.70054 47.9532
424 4LX0 BEF GDP 0.000000000006685 0.82239 48.0226
425 3MJH GTP 0.000000000001382 0.70249 48.2143
426 1R2Q GNP 0.000000000003165 0.59134 48.2353
427 1YVD GNP 0.00000000001727 0.66877 48.5207
428 3NKV GNP 0.00000000000781 0.67615 48.5714
429 5TB5 GDP 0.00000000007716 0.77214 48.6486
430 5TAR GDP 0.0000000002027 0.7413 48.6486
431 2HV8 GTP 0.0000000002403 0.74878 48.8372
432 4C4P GNP 0.00000000003535 0.78962 49.1329
433 1ZC3 GNP 0.00000000004469 0.78501 49.1429
434 2D7C GTP 0.0000000001814 0.63269 49.7006
435 1UAD GNP 0.000000000006474 0.67913 49.7143
436 1XTQ GDP 0.0000000002256 0.74335 49.7175
Pocket No.: 2; Query (leader) PDB : 2GCO; Ligand: GNP; Similar sites found: 6
This union binding pocket(no: 2) in the query (biounit: 2gco.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3IUY AMP 0.001828 0.40279 None
2 1QXA GLY GLY GLY 0.02679 0.4015 5.47264
3 2WZF BGC 0.007921 0.42805 7.46269
4 4O48 ASP 0.02676 0.40096 7.46269
5 1L2T ATP 0.001388 0.40097 9.95025
6 3QKT ANP 0.001502 0.40067 9.95025
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