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Receptor
PDB id Resolution Class Description Source Keywords
2GN4 1.9 Å EC: 4.2.1.- CRYSTAL STRUCTURE OF UDP-GLCNAC INVERTING 4,6-DEHYDRATASE IN WITH NADPH AND UDP-GLCNAC HELICOBACTER PYLORI ROSSMANN FOLD TYK TRIAD SDR ENZYME DEHYDRATASE UDP-GLCNNADPH LYASE
Ref.: STRUCTURAL STUDIES OF FLAA1 FROM HELICOBACTER PYLOR THE MECHANISM FOR INVERTING 4,6-DEHYDRATASE ACTIVIT J.BIOL.CHEM. V. 281 24489 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MES B:336;
B:337;
Invalid;
Invalid;
none;
none;
submit data
195.237 C6 H13 N O4 S C1COC...
NDP A:334;
B:334;
Valid;
Valid;
none;
none;
submit data
745.421 C21 H30 N7 O17 P3 c1nc(...
UD1 A:335;
B:335;
Valid;
Valid;
none;
none;
submit data
607.354 C17 H27 N3 O17 P2 CC(=O...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2GN4 1.9 Å EC: 4.2.1.- CRYSTAL STRUCTURE OF UDP-GLCNAC INVERTING 4,6-DEHYDRATASE IN WITH NADPH AND UDP-GLCNAC HELICOBACTER PYLORI ROSSMANN FOLD TYK TRIAD SDR ENZYME DEHYDRATASE UDP-GLCNNADPH LYASE
Ref.: STRUCTURAL STUDIES OF FLAA1 FROM HELICOBACTER PYLOR THE MECHANISM FOR INVERTING 4,6-DEHYDRATASE ACTIVIT J.BIOL.CHEM. V. 281 24489 2006
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2GN4 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
2 2GN8 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2GN4 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
2 2GN8 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 2GN4 - NDP C21 H30 N7 O17 P3 c1nc(c2c(n....
2 2GN8 - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
3 3W1V - UDZ C17 H27 N6 O16 P2 CC(=O)N[C@....
4 3VVC - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
5 4G5H - NAP C21 H28 N7 O17 P3 c1cc(c[n+]....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NDP; Similar ligands found: 172
No: Ligand ECFP6 Tc MDL keys Tc
1 NDP 1 1
2 0WD 0.827273 1
3 NAI 0.803738 0.986842
4 NMN AMP PO4 0.794643 0.948052
5 NPW 0.692308 0.962025
6 NZQ 0.686441 0.987013
7 1DG 0.68 1
8 DG1 0.68 1
9 A2R 0.650943 0.909091
10 A22 0.64486 0.934211
11 TXP 0.644628 0.924051
12 ATR 0.640777 0.894737
13 NA7 0.636364 0.886076
14 XNP 0.620968 0.949367
15 AP0 0.598361 0.948718
16 A2P 0.598039 0.881579
17 NJP 0.574803 0.923077
18 25L 0.550847 0.934211
19 ODP 0.550388 0.936709
20 NAX 0.544 0.949367
21 25A 0.53913 0.921053
22 80F 0.537879 0.914634
23 2AM 0.529412 0.87013
24 6V0 0.519685 0.974026
25 NAP 0.514493 0.922078
26 7L1 0.507143 0.763441
27 EAD 0.507143 0.949367
28 A2D 0.504673 0.921053
29 TXE 0.503876 0.935897
30 NA0 0.496454 0.910256
31 TXD 0.496124 0.911392
32 SAP 0.495575 0.875
33 AGS 0.495575 0.875
34 P1H 0.493056 0.925926
35 CO7 0.489796 0.791209
36 TAP 0.489362 0.864198
37 PAP 0.482456 0.907895
38 BA3 0.481818 0.921053
39 NAJ PZO 0.478261 0.924051
40 ATP 0.477876 0.921053
41 HEJ 0.477876 0.921053
42 B4P 0.477477 0.921053
43 AP5 0.477477 0.921053
44 ADP 0.477477 0.921053
45 OAD 0.47541 0.897436
46 AR6 0.473684 0.896104
47 AQP 0.473684 0.921053
48 5FA 0.473684 0.921053
49 APR 0.473684 0.896104
50 AN2 0.473214 0.909091
51 3OD 0.467742 0.897436
52 50T 0.464912 0.884615
53 NAJ PYZ 0.464789 0.879518
54 9X8 0.463415 0.851852
55 PO4 PO4 A A A A PO4 0.463415 0.857143
56 V3L 0.461538 0.896104
57 2A5 0.46087 0.85
58 AT4 0.460177 0.886076
59 A1R 0.459016 0.841463
60 4AD 0.459016 0.875
61 ADQ 0.459016 0.897436
62 OVE 0.458716 0.8375
63 OMR 0.458647 0.813953
64 PPS 0.457627 0.811765
65 AD9 0.456897 0.897436
66 CA0 0.45614 0.897436
67 M33 0.45614 0.884615
68 ADJ 0.455882 0.879518
69 A3P 0.455357 0.894737
70 ACP 0.452174 0.897436
71 ENP 0.451613 0.85
72 UP5 0.451128 0.948052
73 SRP 0.45 0.8625
74 ANP 0.449153 0.897436
75 ACQ 0.449153 0.897436
76 PRX 0.448276 0.82716
77 A3R 0.447154 0.841463
78 5AL 0.445378 0.884615
79 7D4 0.443478 0.8375
80 ADX 0.443478 0.811765
81 6YZ 0.438017 0.897436
82 A 0.436364 0.894737
83 AMP 0.436364 0.894737
84 4TC 0.433824 0.924051
85 7D3 0.433628 0.8375
86 DCA 0.433566 0.788889
87 ETB 0.433566 0.797753
88 BIS 0.433071 0.864198
89 1ZZ 0.433071 0.802326
90 00A 0.432 0.864198
91 ATF 0.429752 0.886076
92 DQV 0.428571 0.934211
93 0T1 0.427586 0.788889
94 5SV 0.427419 0.788235
95 8QN 0.427419 0.884615
96 3AM 0.427273 0.857143
97 N01 0.426573 0.884615
98 PR8 0.425197 0.811765
99 LAD 0.425197 0.821429
100 WAQ 0.425197 0.841463
101 DTP 0.425 0.8375
102 AMO 0.424 0.886076
103 PAJ 0.424 0.843373
104 APC 0.423729 0.886076
105 UPA 0.423358 0.935897
106 48N 0.422222 0.853659
107 FYA 0.421875 0.860759
108 PTJ 0.421875 0.853659
109 CNA 0.421429 0.910256
110 PUA 0.42069 0.9125
111 DND 0.419118 0.910256
112 NXX 0.419118 0.910256
113 AV2 0.418033 0.848101
114 COA 0.417808 0.788889
115 3UK 0.417323 0.897436
116 OOB 0.416 0.909091
117 IVC 0.415584 0.78022
118 DAT 0.415254 0.8375
119 NDO 0.414966 0.897436
120 139 0.414286 0.901235
121 B5V 0.414062 0.886076
122 T99 0.413223 0.886076
123 TAT 0.413223 0.886076
124 3AT 0.413223 0.896104
125 YLB 0.413043 0.784091
126 62F 0.4125 0.823529
127 ABM 0.412281 0.848101
128 B5M 0.412214 0.875
129 YAP 0.412214 0.875
130 YLP 0.411765 0.784091
131 NB8 0.410853 0.853659
132 ME8 0.410853 0.802326
133 SON 0.410256 0.886076
134 DLL 0.409449 0.909091
135 AHX 0.409449 0.853659
136 CAO 0.409396 0.763441
137 30N 0.409396 0.72449
138 AMX 0.409396 0.797753
139 COS 0.409396 0.771739
140 7D5 0.409091 0.8125
141 4UW 0.408759 0.9125
142 F2R 0.408451 0.825581
143 APX 0.407692 0.841463
144 SRA 0.40708 0.85
145 CMX 0.406667 0.788889
146 SCO 0.406667 0.788889
147 TYM 0.405797 0.886076
148 COD 0.405594 0.777778
149 CA6 0.405229 0.70297
150 OXK 0.405229 0.771739
151 AP2 0.405172 0.886076
152 A12 0.405172 0.886076
153 9SN 0.40458 0.853659
154 LAQ 0.404412 0.802326
155 T5A 0.404255 0.914634
156 FAM 0.403974 0.771739
157 ACO 0.403974 0.763441
158 FCX 0.403974 0.763441
159 VO4 ADP 0.403226 0.860759
160 ADP VO4 0.403226 0.860759
161 YLC 0.402878 0.823529
162 1VU 0.402597 0.763441
163 B5Y 0.401515 0.875
164 FA5 0.401515 0.886076
165 HAX 0.401316 0.771739
166 AR6 AR6 0.4 0.871795
167 CAJ 0.4 0.771739
168 AFH 0.4 0.843373
169 APU 0.4 0.923077
170 A U 0.4 0.898734
171 TXA 0.4 0.886076
172 4UU 0.4 0.948052
Ligand no: 2; Ligand: UD1; Similar ligands found: 79
No: Ligand ECFP6 Tc MDL keys Tc
1 UD2 1 1
2 UD1 1 1
3 UDZ 0.8 0.893333
4 HP7 0.793814 0.985294
5 EPZ 0.75 0.985507
6 EPU 0.742857 0.971429
7 EEB 0.742857 0.971429
8 F5P 0.742574 0.957143
9 UD4 0.742574 0.957143
10 F5G 0.742574 0.971014
11 UFM 0.73913 0.985294
12 GUD 0.73913 0.985294
13 UPG 0.73913 0.985294
14 GDU 0.73913 0.985294
15 UD7 0.722772 0.971014
16 MJZ 0.715686 0.957143
17 U2F 0.697917 0.930556
18 UPF 0.697917 0.930556
19 UMA 0.690265 0.985507
20 UDM 0.683168 0.957143
21 UFG 0.663265 0.930556
22 12V 0.660377 0.943662
23 HWU 0.660377 0.943662
24 U22 0.655462 0.85
25 U20 0.655462 0.871795
26 U21 0.655462 0.871795
27 UGB 0.65 0.970588
28 UGA 0.65 0.970588
29 USQ 0.633663 0.835443
30 UDX 0.63 0.956522
31 UAD 0.63 0.956522
32 UDP 0.622222 0.927536
33 UTP 0.619565 0.927536
34 UAG 0.617188 0.931507
35 660 0.6 0.942857
36 URM 0.6 0.942857
37 G3N 0.596154 0.929577
38 UPU 0.587629 0.955882
39 4RA 0.584615 0.87013
40 UNP 0.583333 0.901408
41 3UC 0.575472 0.930556
42 UML 0.564286 0.871795
43 IUG 0.561404 0.825
44 U5P 0.555556 0.913043
45 U 0.555556 0.913043
46 UD0 0.552239 0.858974
47 UPP 0.543689 0.928571
48 UDH 0.543689 0.855263
49 2KH 0.530612 0.901408
50 44P 0.521277 0.888889
51 C5G 0.518519 0.930556
52 UDP UDP 0.505155 0.898551
53 Y6W 0.504673 0.90411
54 2QR 0.485075 0.860759
55 2GW 0.482759 0.943662
56 URI 0.477273 0.852941
57 UP5 0.47541 0.844156
58 PMP UD1 0.467626 0.848101
59 1GW 0.467213 0.905405
60 CJB 0.461538 0.838235
61 UAG API 0.457516 0.87013
62 4TC 0.456 0.822785
63 CSV 0.452991 0.866667
64 CSQ 0.452991 0.866667
65 U3P 0.447917 0.898551
66 UA3 0.447917 0.898551
67 U U 0.446429 0.914286
68 NG1 0.444444 0.753623
69 GN1 0.444444 0.753623
70 C30 0.433628 0.696203
71 PUP 0.429825 0.875
72 CXY 0.422414 0.90411
73 A U 0.418605 0.820513
74 U2P 0.418367 0.913043
75 UMA FGA LYS DAL DAL 0.414634 0.8375
76 U1S 0.409091 0.789474
77 FN5 0.40458 0.883117
78 DAU 0.403361 0.905405
79 G U 0.401515 0.780488
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2GN4; Ligand: NDP; Similar sites found with APoc: 870
This union binding pocket(no: 1) in the query (biounit: 2gn4.bio1) has 92 residues
No: Leader PDB Ligand Sequence Similarity
1 5JE8 NAD 0.993378
2 5YJF 8WO 1.05634
3 2I3G NAP 1.16279
4 3LST SAH 1.45349
5 3GFB NAD 1.45349
6 4RQU NAD 1.45349
7 3DMH SAM 1.45349
8 1E3I CXF 1.45349
9 4N49 SAM 1.45349
10 1TI7 NAP 1.45349
11 3G5S FAD 1.45349
12 3DMH GMP 1.45349
13 1Q19 SSC 1.45349
14 1KOL NAD 1.45349
15 4Z0H NAD 1.49701
16 5MW4 5JU 1.49701
17 1I36 NAP 1.51515
18 3A28 NAD 1.55039
19 1FK8 NAD 1.55642
20 3LKZ SFG 1.55763
21 1GV0 NAD 1.6129
22 2BD0 NAP 1.63934
23 4Y9D NAI 1.63934
24 5N6C NAD 1.66667
25 4ONQ SFG 1.74419
26 1X7D NAD 1.74419
27 1VJT NAD 1.74419
28 2O4C NAD 1.74419
29 1X7D ORN 1.74419
30 2DPM SAM 1.76056
31 5FUB SAH 1.78042
32 1RJD SAM 1.79641
33 3I53 SAH 1.80723
34 2Q7V FAD 1.84615
35 1G60 SAM 1.92308
36 5A96 GTP 2.00803
37 4Q9N NAI 2.01342
38 5Y8L HUI 2.0339
39 5Y8L NAD 2.0339
40 1F8G NAD 2.03488
41 5ZI2 NAD 2.03488
42 5ZI2 ADP 2.03488
43 1SAY PYR 2.03488
44 5Z20 NAI 2.03488
45 2VHW NAI 2.03488
46 5THY SAH 2.03488
47 5NMX FAD 2.03488
48 2NAD NAD 2.03488
49 3FPF MTA 2.03488
50 3FPF TNA 2.03488
51 5THZ SAH 2.03488
52 6AIN FAD 2.03488
53 3GMB FAD 2.03488
54 3O7W SAM 2.04082
55 4M37 SAH 2.04082
56 2AOT SAH 2.05479
57 1DSS NAD 2.1021
58 1GAD NAD 2.12121
59 1V35 NAI 2.12766
60 1I9G SAM 2.14286
61 5M58 SAH 2.17391
62 1DRV A3D 2.1978
63 6ECU SAH 2.21519
64 6ECW SAH 2.22222
65 5ULP KB1 2.23881
66 5E8J SAH 2.24359
67 5E9W SAH 2.24359
68 3VYW SAM 2.27273
69 2V6G NAP 2.32558
70 2X6T NAP 2.32558
71 5MLR NAP 2.32558
72 5MLR GRQ 2.32558
73 1SQF SAM 2.32558
74 1X87 NAD 2.32558
75 4KIB SAH 2.32558
76 4R5M NAP 2.32558
77 1BW9 NAD 2.32558
78 3L9W GSH 2.32558
79 3L9W AMP 2.32558
80 4DPL NAP 2.32558
81 2GCG NDP 2.32558
82 2X6T ADP BMA 2.32558
83 1C1X NAD 2.32558
84 1BXG NAD 2.32558
85 4R5M 4NO 2.32558
86 5DN9 NAD 2.32558
87 3PT9 SAH 2.32558
88 4USQ FAD 2.32558
89 3MCT SAH 2.3569
90 3B20 NAD 2.35988
91 3B1J NAD 2.35988
92 4ZA2 NAD 2.37154
93 4M73 SAH 2.37389
94 4M73 M72 2.37389
95 4B7X NAP 2.38095
96 2CFC NAD 2.4
97 5NUF NAD 2.40964
98 9LDB NAD 2.40964
99 5NUE NAD 2.40964
100 9LDT NAD 2.40964
101 1KPG SAH 2.43902
102 1WG8 SAM 2.45614
103 4YMH SAH 2.5
104 2HNK SAH 2.51046
105 2HK9 ATR 2.54545
106 2HK9 NAP 2.54545
107 3VC1 SAH 2.5641
108 2Q0L NAP 2.57235
109 3A27 SAM 2.57353
110 6EL3 NAP 2.61628
111 1FP2 SAH 2.61628
112 2IZ1 ATR 2.61628
113 4ZGS NAD 2.61628
114 5DNK SAH 2.61628
115 1U1I NAD 2.61628
116 4DMG SAM 2.61628
117 1X14 NAD 2.61628
118 5YF1 SFG 2.61628
119 2XVF FAD 2.61628
120 1XHC FAD 2.61628
121 5YU3 PRO 2.61628
122 5YU3 NAD 2.61628
123 3TKA SAM 2.61628
124 2RGJ FAD 2.61628
125 1I8T FAD 2.61628
126 5YF1 8V0 2.61628
127 4IWN GEK 2.62009
128 5CG1 NAD BBN 2.62295
129 5A1T NAI 2.6393
130 5A1T OXM 2.6393
131 5Z2F NAP 2.64151
132 3A25 SAM 2.65781
133 1RPN NDP 2.68657
134 6FDF SAH 2.69461
135 4JK3 NAD 2.7027
136 4J4H 1J1 2.7027
137 4J4H NAI 2.7027
138 1J0X NAD 2.71084
139 5U5G NAP 2.71186
140 1CER NAD 2.71903
141 2HJR APR 2.7439
142 2CVQ NDP 2.75229
143 5JGL SAM 2.76817
144 3SJ7 NDP 2.77778
145 3EWP APR 2.82486
146 5GWT NAD 2.8777
147 5GWT SIN 2.8777
148 5X20 NAD 2.88462
149 3VPH NAD 2.90323
150 3VPH OXM 2.90323
151 3ICT ADP 2.90698
152 3ICS ADP 2.90698
153 3OJO NAD 2.90698
154 3I6I NDP 2.90698
155 1H9A NAP 2.90698
156 4KRG SAH 2.90698
157 4XQC NAD 2.90698
158 1EBF NAD 2.90698
159 5MQ6 NDP 2.90698
160 3VSE SAH 2.90698
161 2B5W NAP 2.90698
162 4XQC 13D 2.90698
163 1U2Z SAH 2.90698
164 2D2I NAP 2.90698
165 5EEH SAH 2.90698
166 1O0S NAI 2.90698
167 1P31 EPU 2.90698
168 1HKU NAD 2.90698
169 5EJ2 NAD 2.92208
170 1O6Z NAD 2.9703
171 5AHO TLA 2.97619
172 1JG3 ADN 2.97872
173 3G2O SAM 3.01003
174 5GM1 SAH 3.0303
175 3GRU AMP 3.05085
176 1NNU NAD 3.05677
177 1NNU TCT 3.05677
178 1U7T NAD 3.06513
179 1U7T TDT 3.06513
180 1QG6 TCL 3.06513
181 1QG6 NAD 3.06513
182 3U31 NAD 3.10345
183 5UAV NDP 3.10559
184 5UAV TFB 3.10559
185 3P2E SAH 3.11111
186 5WUW NAP 3.13589
187 1L1E SAH 3.13589
188 3CH6 NAP 3.14685
189 3CH6 311 3.14685
190 2WSB NAD 3.14961
191 3HVJ 705 3.16742
192 5MSO NAP 3.19767
193 5DF1 58X 3.19767
194 5DF1 NAP 3.19767
195 3BAZ NAP 3.19767
196 2VYN NAD 3.19767
197 1Y8Q ATP 3.19767
198 1PZG A3D 3.19767
199 4RSL FAD 3.19767
200 5KVS NAP 3.19767
201 5GSN FAD 3.19767
202 4W6Z 8ID 3.19767
203 2QA1 FAD 3.19767
204 1M2W NAD 3.19767
205 1V8B NAD 3.19767
206 5EOW FAD 3.19767
207 4D7E FAD 3.19767
208 6A3J NAI 3.19767
209 5W7M SAH 3.20513
210 4PVD NDP 3.21637
211 4URF NAD 3.22581
212 5U5N NAD 3.22581
213 4FC7 NAP 3.2491
214 4FC7 COA 3.2491
215 2AG5 NAD 3.25203
216 2PXX SAH 3.25581
217 3QV1 NAD 3.2641
218 2P41 SAH 3.27869
219 1IM8 SAI 3.27869
220 4BVA NDP 3.28358
221 4BVA T3 3.28358
222 3B9Q MLI 3.31126
223 6A0S HSE 3.31325
224 6A0S NDP 3.31325
225 6GAS FAD 3.32326
226 1EJ0 SAM 3.33333
227 1PNO NAP 3.33333
228 2PV7 NAD 3.3557
229 3T7S SAM 3.35821
230 5L53 NAP 3.39506
231 2DTX BMA 3.40909
232 1GZ6 NAI 3.44828
233 1LTH NAD 3.44828
234 2CDU ADP 3.48837
235 1YS4 NAP 3.48837
236 1DJN ADP 3.48837
237 5JAQ NAI 3.48837
238 5WP5 SAH 3.48837
239 5X62 SAH 3.48837
240 5LOG SAH 3.48837
241 1H2B NAJ 3.48837
242 4JBI NDP 3.48837
243 2FK8 SAM 3.48837
244 4XYB NDP 3.48837
245 3AB1 FAD 3.48837
246 4REP FAD 3.48837
247 5J7X FAD 3.48837
248 2CDU FAD 3.48837
249 3GGO ENO 3.50318
250 3GGO NAI 3.50318
251 3GU3 SAH 3.52113
252 5KOK SAH 3.52645
253 5A04 BGC 3.53982
254 5A04 NDP 3.53982
255 4OM8 NAD 3.55987
256 1RM4 NDP 3.56083
257 6C4N NAP 3.56347
258 2YX1 SFG 3.57143
259 4PLG NAI 3.59281
260 4PLG OXM 3.59281
261 2EWM NAD 3.61446
262 1ZGA SAH 3.64146
263 1B8U NAD 3.64742
264 1B8U OAA 3.64742
265 1KYQ NAD 3.64964
266 3A4T SFG 3.64964
267 2YVJ NAI 3.66972
268 1P77 ATR 3.67647
269 1HDR NAD 3.68852
270 5EIN NAP 3.7037
271 1UAY ADN 3.71901
272 3GDH SAH 3.73444
273 1F06 NDP 3.75
274 5L4S 6KX 3.77907
275 5L4S NAP 3.77907
276 1VKO NAD 3.77907
277 3H9E NAD 3.77907
278 4KRI SAH 3.77907
279 3H2B SAH 3.77907
280 3S5W FAD 3.77907
281 5NA1 FAD 3.77907
282 4UCI SAM 3.77907
283 5JJR SAH 3.77907
284 3S5W NAP 3.77907
285 4A0S NAP 3.77907
286 4PIO SAH 3.77907
287 1Q0H FOM 3.77907
288 4NEC SAH 3.78788
289 1ZEM NAD 3.81679
290 1E3W NAD 3.83142
291 1E6W NAD 3.84615
292 1NVM NAD 3.84615
293 4L8V NAP 3.85757
294 1ZQ9 SAM 3.85965
295 1RP0 AHZ 3.87324
296 4MDH NAD 3.89222
297 5MDH NAD 3.9039
298 2G5C NAD 3.91459
299 1XKQ NDP 3.92857
300 2F1K NAP 3.94265
301 5N5D SAM 3.9823
302 1N2X SAM 3.98671
303 1JA9 NDP 4.0146
304 5E72 SAM 4.04624
305 5T9E NAP 4.05904
306 4EUE NAI 4.06977
307 4A6D SAM 4.06977
308 1PJS NAD 4.06977
309 1E5Q NDP 4.06977
310 3LCC SAH 4.06977
311 3TKY SAH 4.06977
312 5MGZ SAH 4.06977
313 1OBB NAD 4.06977
314 1P0F NAP 4.06977
315 3ULK NDP 4.06977
316 3IHG FAD 4.06977
317 1TB4 PEJ 4.06977
318 3CGB FAD 4.06977
319 4LWP SAH 4.07609
320 6C5B SAH 4.10557
321 3MQ2 SAH 4.12844
322 4XUC SAM 4.12844
323 4XUC 43G 4.12844
324 4OSP NAP 4.18251
325 2ZFU SAH 4.18605
326 4D3F NAP 4.19355
327 1HYH NAD 4.20712
328 1G0N PHH 4.24028
329 1G0N NDP 4.24028
330 5XVH NAP 4.24837
331 3WBF NAP 4.2623
332 3WBF API 4.2623
333 5WQP NAP 4.2735
334 5WQP NCA 4.2735
335 2IXB NAD 4.27928
336 2IXB A2G 4.27928
337 5FTW SAH 4.29688
338 2NXE SAM 4.33071
339 5XNC MTA 4.36047
340 5Z21 NAI 4.36047
341 5F8F SFG 4.36047
342 1W62 PYC 4.36047
343 6GKV SAH 4.36047
344 4C4A SAH 4.36047
345 2A92 NAI 4.36137
346 3EGI ADP 4.36893
347 5J60 FAD 4.375
348 1R18 SAH 4.40529
349 1XSE NDP 4.40678
350 3L4S NAD 4.46429
351 3L4S 3PG 4.46429
352 2WD7 NAP 4.47761
353 2VZ0 D64 4.47761
354 2VZ0 NAP 4.47761
355 3O9Z AKG 4.48718
356 3KB6 NAD 4.49102
357 2JHP SAH 4.50311
358 1QAN SAH 4.5082
359 3OIG NAD 4.51128
360 2XVM SAH 4.52261
361 2AG8 NAP 4.56274
362 5E1M SAH 4.56432
363 5FA5 MTA 4.63215
364 3WMX NAD 4.65116
365 3A06 NDP 4.65116
366 1XDS SAM 4.65116
367 1QZZ SAM 4.65116
368 5CAE COA 4.65116
369 1OMO NAD 4.65116
370 3A06 FOM 4.65116
371 4OHU 2TK 4.65116
372 4OHU NAD 4.65116
373 3EVG SAH 4.65116
374 6B3A SAM 4.65116
375 5CAE SIN 4.65116
376 6F9Q NAD 4.77941
377 5W7K SAH 4.80769
378 3QWI NAP 4.81482
379 3QWI CUE 4.81482
380 2GLX NDP 4.81928
381 1WY7 SAH 4.83092
382 4RDH AMP 4.86111
383 4RDI ATP 4.86111
384 3GWZ SAH 4.94186
385 3CIF NAD 4.94186
386 3GXO SAH 4.94186
387 2EFJ SAH 4.94186
388 5JWC FAD 4.94186
389 1CDO NAD 4.94186
390 3CIF G3H 4.94186
391 2DKH FAD 4.94186
392 3NJ4 NAD 4.94186
393 1YKF NAP 4.94186
394 4X60 SFG 4.94186
395 4JDR FAD 4.94186
396 2AE2 NAP 5
397 2AE2 PTO 5
398 1RJW ETF 5.01475
399 3WV8 ATP 5.04587
400 3OJF NDP 5.05837
401 3OJF IMJ 5.05837
402 4D79 ATP 5.07246
403 1V6A TRE 5.12048
404 4IDC 1XX 5.12048
405 4IDC NDP 5.12048
406 3O26 NDP 5.14469
407 3CBG SAH 5.17241
408 1FWV SGA MAG FUC 5.22388
409 5D4V SAH 5.22388
410 3ICC NAP 5.23256
411 6C4T NA7 5.23256
412 1MUU NAD 5.23256
413 1KJ8 GAR 5.23256
414 4AZW SAM 5.23256
415 5ERG SAM 5.23256
416 1UWK URO 5.23256
417 1UWK NAD 5.23256
418 5EES NAP 5.26316
419 3U4C NDP 5.33808
420 4GKV NAD 5.35714
421 2EG5 SAH 5.37634
422 4YAC NAI 5.38721
423 4O1M NAD 5.39683
424 1J49 NAD 5.40541
425 5AYV NAP 5.50162
426 1ZBQ NAD 5.50459
427 1MV8 NAD 5.52326
428 5H81 NAP 5.52326
429 5LD5 NAD 5.52326
430 2B4R AES 5.52326
431 5X2N ALA 5.52326
432 2B4R NAD 5.52326
433 4K5S FAD 5.52326
434 2HMT NAI 5.55556
435 5YEC ATP 5.58824
436 5L4L NAP 5.59211
437 5L4L 7OX 5.59211
438 3QOX SAH 5.6338
439 4E13 NAD 5.65371
440 4KOA NDP 5.70571
441 6BII NAP 5.70571
442 2BKA NDP 5.78512
443 5OJL TXP 5.81395
444 1LVL NAD 5.81395
445 1UP7 NAD 5.81395
446 5HJM MTA 5.81395
447 1D1T NAD 5.81395
448 3P9C SAH 5.81395
449 4MP8 NAD 5.8997
450 4MP8 MLI 5.8997
451 5AOV NAP 5.95238
452 1XCL SAH 5.95745
453 4PNE SAH 5.96026
454 2DBZ NAP 5.98802
455 5OVL NAP 6
456 3GCZ SAM 6.02837
457 1HYE NAP 6.07029
458 2EV9 NAP 6.08365
459 2EV9 SKM 6.08365
460 3ABI NAD 6.10465
461 1V59 NAD 6.10465
462 5MPT SAH 6.10465
463 2GVC FAD 6.10465
464 3TWO NDP 6.10465
465 2GV8 FAD 6.10465
466 1VQW FAD 6.10465
467 5KVA SAM 6.11511
468 1G55 SAH 6.12245
469 1MXH DHF 6.15942
470 1MXH NAP 6.15942
471 2DT5 NAD 6.16114
472 5OCM NAP 6.18557
473 3K5I AIR 6.20347
474 4NBW NAD 6.22568
475 4YAG NAI 6.22837
476 5XWV NDP 6.25
477 5XWV 8H6 6.25
478 1LUA NAP 6.27178
479 5Y77 FAD 6.34249
480 4E5N NAD 6.36364
481 2NU8 COA 6.39535
482 4CJX NAP 6.39535
483 2BRY FAD 6.39535
484 4TXI FAD 6.39535
485 5KMS FAD 6.39535
486 1YB5 NAP 6.39535
487 4USR FAD 6.39535
488 3G89 SAM 6.4257
489 1LSS NAD 6.42857
490 2UYQ SAM 6.45161
491 3WLE NAD 6.45161
492 3O03 NAP 6.52921
493 1NFQ NAI 6.53846
494 2XYQ SAH 6.55738
495 1Z82 NDP 6.56716
496 4NBT NAD 6.66667
497 1VI2 NAD 6.66667
498 4HXY NDP 6.68605
499 3V1U NAD 6.68605
500 4K26 NDP 6.68605
501 4K26 SFF 6.68605
502 1PL6 NAD 6.68605
503 3SSO SAH 6.68605
504 1GR0 NAD 6.68605
505 1PL6 572 6.68605
506 5FI3 NAP 6.68605
507 3ORF NAD 6.77291
508 1UXG NAD 6.79612
509 1UXG FUM 6.79612
510 1YQD NAP 6.8306
511 6ECT SAM 6.85358
512 4XB2 NDP 6.86567
513 4XB2 HSE 6.86567
514 5EPO NAP 6.87023
515 1NPD NAD 6.94444
516 6AA8 NAD 6.95364
517 1Q7B NAP 6.96721
518 3TLJ SAH 6.97051
519 4PIV NDP 6.97674
520 1E6E FAD 6.97674
521 5OVK NDP 7.03125
522 1P1C SAH 7.03518
523 4YSX FAD 7.05128
524 3ITJ CIT 7.10059
525 6A6A DAL 7.11111
526 2BGM NAJ 7.19424
527 2DC1 NAD 7.20339
528 1U8X NAD 7.20339
529 2OOR NAD 7.26744
530 1NM5 NAD 7.26744
531 1GZ4 ATP 7.26744
532 1L7E NAI 7.26744
533 5GZ6 NDP 7.26744
534 2ZXI FAD 7.26744
535 5GZ6 7C3 7.26744
536 2OOR TXP 7.26744
537 1LDN NAD 7.27848
538 1GEE NAD 7.27969
539 1UZN NAP 7.28745
540 1KPH SAH 7.31707
541 2FR1 NDP 7.40741
542 1D7O TCL 7.40741
543 1D7O NAD 7.40741
544 2GDZ NAD 7.49064
545 1Y1P NMN AMP PO4 7.55814
546 1WDK NAD 7.55814
547 1NYT NAP 7.55814
548 2JJQ SAH 7.55814
549 1R37 NAD 7.55814
550 3X0D SAH 7.55814
551 4XZ3 COA 7.55814
552 1RM0 NAI 7.55814
553 1RM0 D6P 7.55814
554 5GT9 NAP 7.60456
555 3FPZ AHZ 7.66871
556 5B4T NAD 7.69231
557 5B4T 3HR 7.69231
558 5ZZ6 ADP 7.69231
559 5ZZ6 NAD 7.69231
560 5T9F TYR 7.74908
561 5T9F NAP 7.74908
562 2Y6Q FAD 7.84884
563 3H5N ATP 7.84884
564 4OOE NDP 7.84884
565 6C8R SAH 7.84884
566 4OOE FOM 7.84884
567 5VN0 NAI 7.84884
568 1KEV NDP 7.84884
569 5CUQ NSC 7.86517
570 3SJU NDP 7.8853
571 2RH4 EMO 7.94224
572 1XHL NDP 8.08081
573 6CEP NAD 8.08383
574 6CEP OXM 8.08383
575 5K4W NAI 8.09969
576 5K4W THR 8.09969
577 2VDV SAM 8.13008
578 1F8F NAD 8.13953
579 3KLJ FAD 8.13953
580 1TPY SAH 8.13953
581 1DLJ NAI 8.13953
582 5TC4 NAD 8.22785
583 1YJQ NAP 8.25082
584 1GUZ NAD 8.3871
585 5UR0 NAD 8.43023
586 6D6Y SAH 8.43023
587 1SC6 NAD 8.43023
588 2GSD NAD 8.43023
589 4YCA NDP 8.5034
590 5X9D 80F 8.55263
591 5Z2L NDP 8.57143
592 4J7U NAP 8.68056
593 4J7U YTZ 8.68056
594 1J5P NAD 8.69565
595 3FRH SAH 8.69565
596 5DX1 SFG 8.72093
597 5DWQ SFG 8.72093
598 5DX8 SFG 8.72093
599 5DXA SFG 8.72093
600 5DX0 SFG 8.72093
601 4KWI NAP 8.74525
602 4KWI 1TJ 8.74525
603 5L95 AMP 8.75
604 3JWH SAH 8.75576
605 4Z7X 3CX 8.82353
606 1L3I SAH 8.85417
607 1CF2 NAP 8.90208
608 1W73 NAP 8.9404
609 1W8D NAP 8.9404
610 1W6U NAP 8.9404
611 1W6U HXC 8.9404
612 5KKA 6V0 8.97436
613 1FP1 SAH 9.01163
614 2DKN NAI 9.01961
615 1XTP SAI 9.05512
616 5IN4 6CK 9.06593
617 5IN4 GDP 9.06593
618 5IN4 NAP 9.06593
619 3OA2 NAD 9.1195
620 5BSZ SAH 9.2
621 4ITU NAI 9.29368
622 4ITU 1HS 9.29368
623 1KYZ SAH 9.30233
624 2VUT NAD 9.30233
625 1KYZ FER 9.30233
626 2YYY NAP 9.32945
627 2PT9 S4M 9.34579
628 4CQM NAP 9.42623
629 2CUL FAD 9.48276
630 4RF2 NAP 9.55882
631 1Z6Z NAP 9.57447
632 2Q28 ADP 9.59302
633 1K3T BRZ 9.59302
634 1DJL NAP 9.66184
635 1WP4 NDP 9.68858
636 2CVZ NDP 9.68858
637 3JQA NAP 9.72222
638 3BMO NAP 9.72222
639 5JDI NAP 9.72222
640 3BMQ NAP 9.72222
641 3JQ8 NAP 9.72222
642 4CM8 NAP 9.72222
643 3JQB NAP 9.72222
644 3JQF NAP 9.72222
645 4CM4 NAP 9.72222
646 4CLO NAP 9.72222
647 3JQ9 NAP 9.72222
648 3JQG NAP 9.72222
649 5JDC NAP 9.72222
650 5JCJ NAP 9.72222
651 4CLR NAP 9.72222
652 5K6A NAP 9.72222
653 3JQ7 NAP 9.72222
654 4CM9 NAP 9.72222
655 4CMI NAP 9.72222
656 4CME NAP 9.72222
657 3BMN NAP 9.72222
658 5JDI 6JO 9.72222
659 5FFF 5XC 9.72763
660 5FFF NAP 9.72763
661 2VT3 ATP 9.76744
662 5ZW3 SAH 9.77778
663 1HDC CBO 9.84252
664 1NV8 MEQ 9.85915
665 1NV8 SAM 9.85915
666 2DFV NAD 9.88372
667 1F3L SAH 9.96885
668 6BQ6 TER 9.96979
669 4POO SAM 10
670 1OAA OAA 10.0386
671 1IY8 NAD 10.1124
672 1JQ3 AAT 10.1351
673 3FGZ BEF 10.1562
674 3WQQ IB3 10.1744
675 3WQQ NDP 10.1744
676 1EDO NAP 10.2459
677 3H8V ATP 10.274
678 5FEU NAP 10.3093
679 3FUU ADN 10.3321
680 1A5Z NAD 10.3448
681 3OID NDP 10.4651
682 2B4Q NAP 10.5072
683 2O07 MTA 10.5263
684 3B1F NAD 10.6897
685 5OJI NAP 10.7692
686 5OJI ISN 10.7692
687 3K1X DBX 10.7692
688 2ZIF SAM 10.7744
689 2JL1 NAP 10.8014
690 5G4L NDP 10.8392
691 1D4O NAP 10.8696
692 2PD4 DCN 10.9091
693 2PD4 NAD 10.9091
694 5O4J PJL 10.9489
695 5O4J SAH 10.9489
696 5O4J 9KH 10.9489
697 3C3Y SAH 10.9705
698 4J1Q NDP 11.0465
699 5WP4 SAH 11.0465
700 5F5N NAD 11.0727
701 3H4V DVP 11.1111
702 3H4V NAP 11.1111
703 1HDG NAD 11.1446
704 3VZS NAP 11.284
705 3VZS CAA 11.284
706 2EXX NAP 11.4379
707 1VE3 SAM 11.4537
708 1T26 NAI 11.4907
709 1T26 GBD 11.4907
710 1X1T NAD 11.5385
711 1ZK4 AC0 11.5538
712 1ZK4 NAP 11.5538
713 1SOW NAD 11.5854
714 2GZ3 NAP 11.6279
715 6GAR FAD 11.6279
716 5N2I NAP 11.6379
717 6DUB SAH 11.7117
718 1ZH8 NAP 11.7647
719 1VM6 NAD 11.8421
720 5X68 FAD 11.9186
721 5A9A UTP 11.9342
722 1AE1 NAP 12.0879
723 1I2B UPG 12.1287
724 1I2B NAD 12.1287
725 1I2B USQ 12.1287
726 4FZV SAM 12.1339
727 3C1O NAP 12.1495
728 3V1Y NAD 12.1662
729 1C3V NDP 12.2449
730 5FA8 SAM 12.4224
731 1YXM ADE 12.5413
732 3BXO SAM 12.5523
733 2WYV NAD 12.6437
734 5I7S NAD 12.6812
735 5I7S E9P 12.6812
736 6C4M NAP 12.7907
737 1O94 ADP 12.8788
738 1LDM NAD 13.0699
739 5DOZ NDP 13.0814
740 5ZEC NAP 13.1579
741 1DL5 SAH 13.3721
742 1QMG APX 13.3721
743 1LLU NAD 13.4503
744 4II2 ATP 13.4969
745 5O42 BGC 13.5036
746 5O42 NAD 13.5036
747 5O42 9JW 13.5036
748 4OBW SAM 13.6187
749 1GQ2 NAP 13.6628
750 2QZZ NAP 13.8365
751 2QZZ EMF 13.8365
752 2ZAT NAP 13.8462
753 3AFN NAP 13.9535
754 4UP3 NDP 14.0127
755 2PK3 A2R 14.0187
756 2PK3 GDD 14.0187
757 2Q1S NAI 14.2442
758 1N7G NDP 14.2442
759 1N7G GDR 14.2442
760 3HB5 NAP 14.3731
761 1H5Q NAP 14.717
762 1O5I NAD 14.8594
763 1EK6 NAI 15.2299
764 1EK6 UPG 15.2299
765 4FN4 NAD 15.3543
766 1KEW NAD 15.407
767 1KEW TYD 15.407
768 1XG5 NAP 15.4122
769 1NVT NAP 15.6794
770 1JAY NAP 16.0377
771 3DUW SAH 16.1435
772 1A27 NAP 16.263
773 1I1N SAH 16.3717
774 1GEG NAD 16.4062
775 3NUG NAD 16.5992
776 4GLL NAD 16.6172
777 2C29 NAP 16.6172
778 2C29 DQH 16.6172
779 1WMA NDP 16.6667
780 1WMA AB3 16.6667
781 4D42 NAP 16.6667
782 4D42 W0I 16.6667
783 4R1S NAP 17.2107
784 1BXK NAD 17.4419
785 1RKX NAD 17.7326
786 1OC2 TDX 17.7326
787 1OC2 NAD 17.7326
788 1E7S NAP 17.757
789 4PLT NAI 17.8248
790 4PLT OXM 17.8248
791 5YSS NAD 17.9688
792 2Q2V NAD 18.0392
793 1ORR NAD 18.314
794 1ORR CDP 18.314
795 1SNY NAP 18.3521
796 1BDB NAD 18.7726
797 4NBU NAI 18.8
798 5Z75 NAD 19.2661
799 1EZ4 NAD 19.4969
800 3ZV6 NAD 19.573
801 3ZV6 4HB 19.573
802 5BW4 SAM 19.8502
803 5Y1G NAD 20.122
804 5Y1G AKB 20.122
805 3A4V PYR 20.1893
806 3A4V NAD 20.1893
807 5O98 NAP 20.1893
808 1N5D NDP 20.4861
809 3RFV NAI 20.5993
810 3RFV 15L 20.5993
811 4QTU SAM 20.7407
812 3MB5 SAM 20.7843
813 1EQ2 NAP 20.9677
814 1EQ2 ADQ 20.9677
815 5OOH NAP 22.3301
816 5OOH 9ZZ 22.3301
817 2PZM NAD 22.4242
818 2PZM UDP 22.4242
819 5BSH PRO 22.7437
820 2YY7 NAD 22.7564
821 1UDB UFG 23.0769
822 1UDB NAD 23.0769
823 3RJ5 NAD 23.622
824 2Q1W NAD 23.7237
825 1WVG APR 23.8372
826 1WVG CXY 23.8372
827 2PWY SAH 24.031
828 1Z45 NAD 24.1279
829 1Z45 UPG 24.1279
830 1SB8 NAD 24.1477
831 1SB8 UD2 24.1477
832 1VL0 NAI 24.3151
833 3LU1 NAD 24.4186
834 1GY8 NAD 24.4186
835 3LU1 UD2 24.4186
836 1GY8 UDP 24.4186
837 4U7W NDP 25.2907
838 4O0L NDP 25.4545
839 1VL8 NAP 25.8427
840 2C5A NAD 25.8721
841 2C5A GDC 25.8721
842 6F5Z SAH 26.2295
843 3AY6 NAI 26.3941
844 3AY6 BGC 26.3941
845 4QED NAP 26.6129
846 1PR9 NAP 26.6393
847 3D3W NAP 26.6393
848 2JAH NDP 26.7206
849 3TN7 NJP 26.8482
850 2JAP NDP 27.1255
851 4GQB 0XU 27.2727
852 5T2U NAP 27.4194
853 3RKR NAP 27.4809
854 5THQ NDP 27.5735
855 3WXB NDP 30.8244
856 1R6D DAU 30.8605
857 1R6D NAD 30.8605
858 4ZRN NAD 32.6923
859 4ZRN UPG 32.6923
860 6DNT NAD 33.1395
861 6DNT EPZ 33.1395
862 6CI9 NAP 34.3629
863 6CI9 F3V 34.3629
864 2Q46 NAP 34.7826
865 3GEG NAD 36.4372
866 3KO8 NAD 37.1795
867 6BWL NAD 39.939
868 6BWL UDP 39.939
869 5BJX NAD 44.186
870 5BJX UDP 44.186
Pocket No.: 2; Query (leader) PDB : 2GN4; Ligand: NDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2gn4.bio1) has 92 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2GN4; Ligand: NDP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2gn4.bio1) has 92 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2GN4; Ligand: UD1; Similar sites found with APoc: 852
This union binding pocket(no: 4) in the query (biounit: 2gn4.bio1) has 95 residues
No: Leader PDB Ligand Sequence Similarity
1 5JE8 NAD 0.993378
2 2I3G NAP 1.16279
3 3GFB NAD 1.45349
4 4RQU NAD 1.45349
5 3LST SAH 1.45349
6 1TI7 NAP 1.45349
7 1E3I CXF 1.45349
8 4N49 SAM 1.45349
9 3G5S FAD 1.45349
10 3DMH SAM 1.45349
11 3DMH GMP 1.45349
12 1KOL NAD 1.45349
13 4Z0H NAD 1.49701
14 5MW4 5JU 1.49701
15 1I36 NAP 1.51515
16 3A28 NAD 1.55039
17 1FK8 NAD 1.55642
18 1GV0 NAD 1.6129
19 2BD0 NAP 1.63934
20 4Y9D NAI 1.63934
21 5N6C NAD 1.66667
22 1X7D NAD 1.74419
23 4ONQ SFG 1.74419
24 1VJT NAD 1.74419
25 2O4C NAD 1.74419
26 1X7D ORN 1.74419
27 5FUB SAH 1.78042
28 3I53 SAH 1.80723
29 1G60 SAM 1.92308
30 5A96 GTP 2.00803
31 4Q9N NAI 2.01342
32 5Y8L NAD 2.0339
33 5Y8L HUI 2.0339
34 1F8G NAD 2.03488
35 5ZI2 NAD 2.03488
36 5ZI2 ADP 2.03488
37 1SAY PYR 2.03488
38 5Z20 NAI 2.03488
39 4TR9 38D 2.03488
40 2VHW NAI 2.03488
41 5NMX FAD 2.03488
42 6AIN FAD 2.03488
43 2NAD NAD 2.03488
44 3GMB FAD 2.03488
45 3AXB FAD 2.03488
46 3O7W SAM 2.04082
47 4M37 SAH 2.04082
48 1DSS NAD 2.1021
49 1GAD NAD 2.12121
50 1V35 NAI 2.12766
51 1I9G SAM 2.14286
52 5M58 SAH 2.17391
53 1DRV A3D 2.1978
54 6ECU SAH 2.21519
55 6ECW SAH 2.22222
56 5ULP KB1 2.23881
57 3VYW SAM 2.27273
58 2X6T NAP 2.32558
59 2V6G NAP 2.32558
60 5MLR NAP 2.32558
61 5MLR GRQ 2.32558
62 1SQF SAM 2.32558
63 1X87 NAD 2.32558
64 4KIB SAH 2.32558
65 2X6T ADP BMA 2.32558
66 1BW9 NAD 2.32558
67 3L9W GSH 2.32558
68 3L9W AMP 2.32558
69 2GCG NDP 2.32558
70 4R5M NAP 2.32558
71 1C1X NAD 2.32558