Receptor
PDB id Resolution Class Description Source Keywords
2HCJ 2.12 Å NON-ENZYME: TRANSCRIPT_TRANSLATE "TRYPSIN-MODIFIED ELONGATION FACTOR TU IN COMPLEX WITH TETRACYCLINE" ESCHERICHIA COLI TRYPSIN-MODIFIED EF-TU GTPASE CENTER COMPLEX WITH TETRACYCLINE TRANSLATION
Ref.: MOLECULAR COMPLEMENTARITY BETWEEN TETRACYCLINE AND THE GTPASE ACTIVE SITE OF ELONGATION FACTOR TU. ACTA CRYSTALLOGR.,SECT.D V. 62 1392 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:999;
Valid;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
GLV B:1004;
Valid;
none;
submit data
74.035 C2 H2 O3 C(=O)...
MG A:998;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
NA B:1001;
B:1002;
B:1003;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
submit data
22.99 Na [Na+]
SO4 A:1005;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
TAC B:888;
Valid;
none;
submit data
444.435 C22 H24 N2 O8 C[C@]...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2HCJ 2.12 Å NON-ENZYME: TRANSCRIPT_TRANSLATE "TRYPSIN-MODIFIED ELONGATION FACTOR TU IN COMPLEX WITH TETRACYCLINE" ESCHERICHIA COLI TRYPSIN-MODIFIED EF-TU GTPASE CENTER COMPLEX WITH TETRACYCLINE TRANSLATION
Ref.: MOLECULAR COMPLEMENTARITY BETWEEN TETRACYCLINE AND THE GTPASE ACTIVE SITE OF ELONGATION FACTOR TU. ACTA CRYSTALLOGR.,SECT.D V. 62 1392 2006
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 257 families.
1 2HCJ - GLV C2 H2 O3 C(=O)C(=O)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 2HCJ - GLV C2 H2 O3 C(=O)C(=O)....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 185 families.
1 2HCJ - GLV C2 H2 O3 C(=O)C(=O)....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Ligand no: 2; Ligand: GLV; Similar ligands found: 5
No: Ligand ECFP6 Tc MDL keys Tc
1 GLV 1 1
2 FUM 0.5 0.666667
3 MAE 0.5 0.666667
4 OXD 0.416667 0.75
5 CCU 0.411765 0.666667
Ligand no: 3; Ligand: TAC; Similar ligands found: 6
No: Ligand ECFP6 Tc MDL keys Tc
1 TAC 1 1
2 CTC 0.644444 0.934426
3 I7T 0.5 0.918033
4 MIY 0.5 0.965517
5 DXT 0.427184 0.929825
6 ATC 0.422018 0.848485
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2HCJ; Ligand: GDP; Similar sites found: 467
This union binding pocket(no: 1) in the query (biounit: 2hcj.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1D5C GDP 0.00000000002441 0.68127 None
2 1EK0 GNP 0.000000000655 0.54509 None
3 4B9E FAH 0.01548 0.40776 1.3289
4 1YTM ATP 0.00002398 0.44667 1.49254
5 2WKQ GTP 0.000000005082 0.54557 1.50602
6 4FCW ADP 0.0001131 0.47351 1.60772
7 3LRE ADP 0.0000003424 0.64957 1.79104
8 3ZS9 ADP ALF 0.0000122 0.42019 1.79104
9 2WOJ ADP ALF 0.00001589 0.41779 1.79104
10 4YS0 ADP 0.0009173 0.41066 1.79104
11 1P9B GDP 0.000004016 0.49728 1.80995
12 4ZNL BEF ADP 0.00001623 0.54253 1.82482
13 1NST A3P 0.001151 0.40361 1.84615
14 1TAD ALF 0.0000000008108 0.5197 1.85185
15 1TAD GDP 0.0000000008108 0.5197 1.85185
16 2F9L GDP 0.00000000007709 0.59862 2.01005
17 2G77 GDP 0.000000000005231 0.703 2.08955
18 5HR5 ADP 0.00004104 0.53172 2.08955
19 5LB3 ADP 0.00009967 0.49819 2.08955
20 2G77 AF3 0.005842 0.42425 2.08955
21 3QF7 ANP 0.000166 0.42219 2.08955
22 5HR5 FLC 0.02128 0.41561 2.08955
23 1OIV GDP 0.00000000006938 0.83797 2.09424
24 1OIX GDP 0.0000000001029 0.8293 2.09424
25 3SBD GNP 0.000000007685 0.51816 2.13904
26 1MH1 GNP 0.000000003473 0.5161 2.15054
27 1G4U GDP 0.000000004274 0.58805 2.17391
28 5MEX SZZ 0.008697 0.44165 2.17391
29 5MEX PAP 0.003071 0.44165 2.17391
30 5K5Z ANP 0.0002131 0.50746 2.2293
31 4LHW GNP 0.0000000003384 0.55383 2.29885
32 4KFU ACP 0.000001673 0.59983 2.35849
33 4R2I ANP 0.000896 0.45896 2.38095
34 4ZG4 VO4 ADP 0.00008157 0.5264 2.38806
35 2D7C GTP 0.00000000008353 0.56967 2.39521
36 1R0X ATP 0.0001315 0.49248 2.44755
37 3ZQ6 ADP ALF 0.000007961 0.42336 2.46914
38 4LPS GDP 0.000000005722 0.6519 2.47934
39 5BQ5 ADP BEF 0.00008965 0.46368 2.6455
40 4P4T GDP 0.00000001908 0.56863 2.68657
41 2ZFI ADP 0.000009791 0.52917 2.68657
42 1CR1 TTP 0.00003737 0.53879 2.7027
43 5J1J ANP 0.000006412 0.44712 2.80702
44 3QXC ATP 0.00002871 0.40891 2.89256
45 2FFQ GSP 0.00000000009946 0.55818 2.92398
46 1YZQ GNP 0.00000000005047 0.56393 2.94118
47 3NHB ADP 0.00001246 0.55709 2.94118
48 1GOJ ADP 0.0000001263 0.67433 2.98507
49 4PPF FLC 0.000002198 0.60096 2.98507
50 5KSZ GCP 0.00000005782 0.59564 2.98507
51 3MJH GTP 0.00000000002905 0.5801 2.98507
52 2ZR9 DTP 0.00003758 0.50302 2.98507
53 1R2Q GNP 0.00000000008287 0.49204 2.98507
54 4DKX GDP 0.000000000003281 0.81858 3.24074
55 2XTZ GSP 0.0000000002609 0.56379 3.28358
56 2QTV GNP 0.000000005616 0.54201 3.28358
57 3TNF GNP 0.0000000001568 0.53869 3.28358
58 1G41 ADP 0.00003872 0.47848 3.28358
59 2C9O ADP 0.00004538 0.43529 3.28358
60 2OZE AGS 0.0002486 0.41821 3.3557
61 1JJV ATP 0.00001528 0.5516 3.39806
62 5X40 ACP 0.000243 0.50261 3.42466
63 3B7G ANP 0.0004841 0.44573 3.47826
64 3UIE ANP 0.00001654 0.49184 3.5
65 1G6H ADP 0.000002391 0.60631 3.50195
66 4GOX A3P 0.00006437 0.4177 3.51438
67 1GOT GDP 0.000000001887 0.58039 3.58209
68 5I0H ADP BEF 0.00008487 0.52109 3.58209
69 4XGU ADP 0.00002152 0.4669 3.58209
70 5VGR GDP 0.00004214 0.45506 3.58209
71 2FNA ADP 0.000005914 0.45243 3.58209
72 5G41 AP5 0.0007259 0.50649 3.58744
73 1KAO GDP 0.0000000001387 0.65406 3.59281
74 3Q72 GNP 0.0000000000364 0.80387 3.61446
75 5UQW GDP 0.00000000006207 0.83703 3.7037
76 4D0N GDP 0.0000000008099 0.71231 3.78378
77 4WZ6 ATP 0.00001181 0.5583 3.7931
78 1TU3 GNP 0.00000000002433 0.58227 3.79747
79 3AQ4 GDP 0.000000000008515 0.77134 3.80435
80 1KMQ GNP 0.000000006894 0.54177 3.80435
81 1JJ7 ADP 0.00000106 0.62769 3.84615
82 1VKJ A3P 0.002919 0.44471 3.85965
83 1MR3 G3D 0.000000000019 0.75697 3.8674
84 5GOE GDP 0.00000000001219 0.73451 3.8806
85 3WYF GTP 0.0000000007473 0.52644 3.8806
86 4PX9 ADP 0.0001575 0.48875 3.8806
87 2OBM ADP 0.0004772 0.48077 3.8806
88 1TX4 ALF GDP 0.00000001047 0.53766 3.9548
89 2Q2Y MKR 0.0004308 0.54118 4.08719
90 1VHT BA3 0.0001387 0.45808 4.12844
91 3Q85 GNP 0.000000000001158 0.83796 4.14201
92 2GDJ ANP 0.00009351 0.48536 4.16667
93 5E5U MLI 0.005788 0.41338 4.16667
94 3ZFD ANP 0.00001405 0.49347 4.1791
95 4HSE ADP 0.00003049 0.49176 4.1791
96 3X1Z GNP 0.0000000005165 0.79983 4.19162
97 4HDO GNP 0.000000000523 0.53864 4.19162
98 5HCN GCP 0.000000000671 0.69529 4.21456
99 1O3Y GTP 0.00000000008889 0.59895 4.21687
100 1J2J GTP 0.0000000003543 0.58129 4.21687
101 2X77 GDP 0.000000000168 0.71927 4.2328
102 4GOJ GNP 0.000000000003419 0.65375 4.2328
103 5IRC GDP 0.00000001807 0.68903 4.30108
104 3RWO GDP 0.00000000006238 0.57334 4.32432
105 5L3V GDP 0.0000002511 0.56953 4.34783
106 1RYH GNP 0.0000000004671 0.67468 4.4335
107 1Z06 GNP 0.00000000003353 0.59388 4.47761
108 2GCN GDP 0.000000002788 0.5641 4.47761
109 4U00 ADP 0.000003022 0.5027 4.5082
110 4QM7 GTP 0.00004577 0.49921 4.67836
111 2XTN GTP 0.0000007164 0.48304 4.70085
112 1Z08 GNP 0.0000000003832 0.57814 4.70588
113 4YC7 GNP 0.000000003194 0.74434 4.77612
114 2AWN ADP 0.0000006752 0.63944 4.77612
115 2J59 GTP 0.00000000008981 0.59804 4.77612
116 1JWY GDP 0.00000002509 0.5951 4.77612
117 2FJU GSP 0.000000003367 0.57749 4.77612
118 3IIJ ADP 0.000007215 0.53546 4.77612
119 1JWY ADP 0.00003165 0.49115 4.77612
120 1J99 AND 0.007322 0.44103 4.77816
121 1GUA GNP 0.0000000003473 0.54098 4.79042
122 2PZE ATP 0.00000418 0.58837 4.80349
123 1VG0 GDP 0.00000000002374 0.83369 4.83092
124 1VG8 GNP 0.00000000008749 0.55824 4.83092
125 3JVH HHV 0.0153 0.42428 4.91803
126 1KY3 GDP 0.0000000001413 0.67232 4.94506
127 2GCO GNP 0.000000002833 0.60952 4.97512
128 1JI0 ATP 0.0003368 0.47971 5
129 5H67 ATP 0.003407 0.43056 5
130 4LJ9 ACP 0.0002144 0.47089 5.07463
131 4KBF AMP 0.003179 0.42675 5.07463
132 3KJI ADP 0.00000866 0.49515 5.11811
133 1KO8 6PG 0.0001561 0.42781 5.14286
134 2D2F ADP 0.00009455 0.52018 5.2
135 4R3L COA 0.04471 0.40563 5.20231
136 5KSP GDP 0.000000009954 0.64313 5.26316
137 4YDS ATP 0.00001406 0.54705 5.26316
138 5KUT GDP 0.000000001358 0.73909 5.29101
139 4DSU GDP 0.00000000009113 0.55556 5.29101
140 3BD9 A3P 0.004767 0.40244 5.35714
141 4ZI2 GNP 0.000000000003035 0.65516 5.37313
142 1VG9 GDP 0.00000000001806 0.82953 5.40541
143 1VG1 GDP 0.000000000004536 0.78114 5.40541
144 4A4Z ANP 0.001006 0.44188 5.40541
145 2XAU ADP 0.0003088 0.44176 5.40541
146 2CBZ ATP 0.0000006618 0.63777 5.48523
147 1XTQ GDP 0.00000000005718 0.60035 5.64972
148 3REF GDP 0.000000004652 0.55572 5.6701
149 3N5C GDP 0.000000000008372 0.80141 5.67164
150 2A5F GTP 0.00000000009426 0.58504 5.67164
151 3LXR GDP 0.000000001035 0.66091 5.72917
152 5XCO GDP 0.00000000003223 0.8272 5.84795
153 1BO4 COA 0.003641 0.4146 5.95238
154 2ZEJ GDP 0.0000000005034 0.53837 5.97015
155 2O0J ADP 0.008366 0.41151 5.97015
156 4MKF AP5 0.0003484 0.51907 5.99078
157 3FWY ADP 0.0000004819 0.5232 6.05096
158 3DKP ADP 0.0003806 0.45969 6.12245
159 3IUY AMP 0.006146 0.40003 6.14035
160 5JCZ GDP 0.0000000002511 0.62468 6.26866
161 2NCD ADP 0.000002536 0.59139 6.26866
162 4R43 GDP 0.00001531 0.52239 6.26866
163 4IDN GNP 0.00005956 0.42322 6.26866
164 1M2O GNP 0.000000001454 0.54243 6.31579
165 4YLG GDP 0.00000000001588 0.84683 6.35838
166 4K81 GTP 0.0000000005542 0.53074 6.43275
167 5E95 GDP 0.0000000001103 0.65787 6.54762
168 5KDO GDP 0.000000001831 0.59492 6.56716
169 1GP2 GDP 0.000000001338 0.57108 6.56716
170 1SVK ALF GDP 0.0000000008335 0.51043 6.56716
171 1BH2 GSP 0.000000003985 0.50654 6.56716
172 2CE7 ADP 0.00002632 0.4822 6.56716
173 5MZN ADP 0.0005918 0.46776 6.56716
174 3RC3 ANP 0.002874 0.42884 6.56716
175 3BFX A3P 0.0005855 0.40992 6.56716
176 1GXU 2HP 0.00169 0.42954 6.59341
177 1CLU DBG 0.0000000007416 0.82241 6.62651
178 3KUD GDP 0.00000000008784 0.62406 6.62651
179 1WQ1 GDP 0.0000000001888 0.584 6.62651
180 1NVU GTP 0.000000000258 0.54481 6.62651
181 1NVV GNP 0.0000000002663 0.54441 6.62651
182 3DDC GNP 0.0000000002844 0.54386 6.62651
183 4WOP CTP 0.0004814 0.40338 6.66667
184 2C5L GTP 0.0000000001161 0.55473 6.83761
185 1S9D GDP 0.00000000001206 0.76558 6.89655
186 5O2T GSP 0.0000000001425 0.55276 6.95187
187 2GJ8 ALF GDP 0.000000000009048 0.58272 6.97674
188 2XT3 ADP 0.0000005697 0.63173 7.16418
189 5I34 GDP 0.000001626 0.5907 7.16418
190 3T34 GDP 0.0000004154 0.4919 7.16418
191 4XFR CIT 0.01095 0.40804 7.16418
192 1FZQ GDP 0.0000000000009556 0.84295 7.18232
193 1WF3 GNP 0.0000000001186 0.55539 7.30897
194 5SZH GNP 0.00000000008837 0.83588 7.38916
195 3RLF ANP 0.0001371 0.40159 7.43243
196 3MD0 GDP 0.000000000004507 0.84695 7.46269
197 4LC1 GDP 0.00000000003303 0.77366 7.46269
198 1OXV ANP 0.00003628 0.51903 7.46269
199 1FP6 ADP 0.000003254 0.50497 7.46269
200 1Z6T ADP 0.00007147 0.44261 7.46269
201 1ZJ6 G3D 0.000000000001827 0.79828 7.48663
202 4QRH 0O2 0.004082 0.43746 7.61905
203 3NC9 TR3 0.04647 0.40472 7.66773
204 1YVD GNP 0.0000000001445 0.56484 7.69231
205 2W2X GSP 0.000000001314 0.59086 7.76119
206 1OW3 GDP 0.000000002881 0.73584 7.77202
207 2HV8 GTP 0.0000000001505 0.5645 7.8125
208 1B0U ATP 0.0001257 0.44448 8.01527
209 3AB3 GDP 0.0000000001849 0.80242 8.0597
210 1F9V ADP 0.000002661 0.5902 8.0597
211 4KVG GTP 0.0000000001929 0.56209 8.0597
212 1ZCB GDP 0.0000000005538 0.55961 8.0597
213 3CX8 GSP 0.0000000006293 0.52601 8.0597
214 2C04 GCP 0.00001042 0.48798 8.0597
215 1RE0 GDP 0.000000000004343 0.84771 8.10811
216 4XOI GTP 0.000000009904 0.72595 8.10811
217 3PCR GTP 0.00000000008302 0.60014 8.10811
218 4FRZ ADP 0.000002265 0.59416 8.10811
219 2IYL GDP 0.0000006069 0.58596 8.10811
220 4XTR ATP 0.00001096 0.57014 8.10811
221 4XTR ADP 0.000007727 0.57014 8.10811
222 4XVU ATP 0.00001482 0.56358 8.10811
223 3H4S ADP 0.0000005663 0.54978 8.10811
224 3E5H GNP 0.0000000007961 0.54711 8.10811
225 1XKV ATP 0.00007564 0.46709 8.10811
226 2FSH ANP 0.001719 0.43944 8.10811
227 2V3V MGD 0.03667 0.43078 8.10811
228 1OYY AGS 0.004675 0.41157 8.10811
229 1QFY FAD 0.04983 0.40026 8.10811
230 3TKL GTP 0.0000000000683 0.58338 8.16327
231 1FQK GDP 0.000000001984 0.56763 8.16327
232 1GWN GTP 0.000000003282 0.57904 8.29268
233 1I4D GDP 0.0000000009698 0.73618 8.33333
234 1DS6 GDP 0.0000000004307 0.72479 8.33333
235 2RCN GDP 0.00000000001977 0.78404 8.35821
236 3COB ADP 0.0000003394 0.64381 8.35821
237 1XPJ TLA 0.04602 0.40262 8.35821
238 1E96 GTP 0.000000007507 0.51892 8.37438
239 4C4P GNP 0.00000000007125 0.84064 8.41121
240 1PUJ GNP 0.000000000007531 0.7206 8.51064
241 2OFW ADX 0.00008535 0.54891 8.65385
242 2EFE GNH 0.0000000001207 0.67876 8.83978
243 3SFV GDP 0.0000000000867 0.62504 8.83978
244 3A4M ADP 0.000004474 0.57133 8.84615
245 3DOE GTP 0.000000000002861 0.63853 8.85417
246 3M1I GTP 0.0000000004942 0.5402 8.90052
247 1YZG GDP 0.000000000002323 0.79463 8.93855
248 1LVG ADP 0.0000007771 0.60845 9.09091
249 1R4A GNP 0.00000000004588 0.59171 9.09091
250 1HE1 GDP 0.000000002664 0.57991 9.09091
251 4GDX GLU 0.004985 0.42959 9.23077
252 1M7B GTP 0.000000001486 0.5889 9.23913
253 2IS6 ADP 0.00006283 0.49259 9.25373
254 3BFV ADP 0.000006605 0.53823 9.5941
255 5JCP GDP ALF 0.000000004166 0.60437 9.7852
256 4DID GDP 0.000000001821 0.67409 9.84456
257 2QEN ADP 0.000007217 0.47985 9.85075
258 3IO3 ADP 0.00001042 0.47126 9.85075
259 5EE5 GTP 0.0000000000654 0.82869 9.85915
260 3KTA AP5 0.00007487 0.4515 9.89011
261 2WMO GTP 0.000000002011 0.64962 10
262 1NJF ADP 0.00001636 0.46037 10
263 1NJF AGS 0.00001983 0.4408 10
264 4BAS GNP 0.0000000008174 0.58344 10.0503
265 1SQ5 ADP 0.000005842 0.52244 10.0649
266 1NF3 GNP 0.000000009451 0.5156 10.2564
267 5HPY GDP 0.000000001978 0.74386 10.3448
268 3GJ0 GDP 0.0000000000215 0.78311 10.4072
269 4DCT GDP 0.000000000002016 0.79657 10.4478
270 1S8F GDP 0.00000000008117 0.54573 10.4478
271 2NGR GDP 0.000000001265 0.67994 10.4712
272 1A4R GNH 0.000000001181 0.62352 10.4712
273 1A4R GDP 0.000000001059 0.60773 10.4712
274 1GRN GDP 0.000000002949 0.60767 10.4712
275 4ITR GDP 0.000000006371 0.58218 10.4712
276 2UZI GTP 0.0000000001539 0.56371 10.5769
277 5BXQ GDP 0.00000000001384 0.8351 10.6481
278 1IBR GNP 0.0000000006285 0.53834 10.6481
279 4AG5 ADP 0.00001235 0.55705 10.8108
280 1YQT ADP 0.00001625 0.5513 10.8108
281 1XP8 AGS 0.00004581 0.51422 10.8108
282 5IRR GSP 0.000001822 0.47968 10.8108
283 4OI4 ATP 0.00008254 0.40876 10.8108
284 4WEI GLC GAL 0.0234 0.40131 10.8108
285 2FH5 GTP 0.0000000000664 0.63162 11.0448
286 4H1V GNP 0.0000002849 0.54384 11.1111
287 5H56 ADP 0.00006803 0.54189 11.2821
288 5H56 TYD 0.00006803 0.54189 11.2821
289 1UAD GNP 0.0000000002306 0.5562 11.4286
290 2HT6 GDP 0.000000000002707 0.85747 11.6418
291 2CJW GDP 0.000000000007567 0.80258 11.6418
292 1M7G AV2 0.000001004 0.59301 11.8483
293 1M7G ADP 0.00001609 0.57225 11.8483
294 1U8Z GDP 0.0000000001629 0.58657 11.9048
295 2A5J GDP 0.00000000001315 0.73503 12.0419
296 3CNL GNP 0.0000000002029 0.76844 12.2137
297 1WA5 GTP 0.0000000008622 0.49703 13.0682
298 1Z2A GDP 0.0000000001868 0.58785 13.0952
299 1CS4 GSP 0.0000000008683 0.53215 13.1343
300 1AZT GSP 0.0000000003338 0.52966 13.1343
301 5GJC ATP 0.00007496 0.50738 13.1343
302 1Z0A GDP 0.00000000001373 0.73467 13.2184
303 1W7J ADP BEF 0.00006074 0.44494 13.245
304 1SVI GDP 0.00000000004354 0.80018 13.3333
305 3W5J GDP 0.00000001325 0.70866 13.4328
306 2A9K GDP 0.00000000008911 0.66047 13.4529
307 3CPJ GDP 0.0000000001013 0.67931 13.5135
308 2Y8E GNP 0.0000000001017 0.57033 13.5135
309 3QBT GNP 0.0000000001085 0.56679 13.5135
310 3DC4 ADP 0.00001707 0.54294 13.5135
311 4BQS K2Q 0.0001359 0.53413 13.5135
312 4BQS ADP 0.00001275 0.52377 13.5135
313 4E03 ADP 0.00002638 0.50028 13.5135
314 3EZ2 ADP 0.0001739 0.4867 13.5135
315 3FKQ ATP 0.000008217 0.48406 13.5135
316 2FAH GDP 0.00001698 0.48372 13.5135
317 2GK6 ADP 0.001668 0.44577 13.5135
318 4P32 ADP 0.000155 0.4068 13.5135
319 3T5G GDP 0.00000000002047 0.83201 13.8158
320 1KSH GDP 0.000000000003425 0.67136 13.8158
321 5TB5 GDP 0.00000000001831 0.83436 14
322 5TAR GDP 0.00000000002715 0.6987 14.1892
323 1XX6 ADP 0.0002298 0.46659 14.6597
324 5UFQ GNP 0.00000000009888 0.83018 14.7541
325 1G16 GDP 0.0000000009079 0.57683 15.2941
326 2ODE ALF GDP 0.0000000008602 0.79131 15.6028
327 4YMU ATP 0.00006856 0.5059 15.8333
328 1ZC3 GNP 0.0000000002182 0.54598 15.9292
329 1F6B GDP 0.00000000005846 0.73871 16.1616
330 4ZKD GDP 0.00000000006388 0.84305 16.2162
331 4LX0 BEF GDP 0.0000000001294 0.82745 16.2162
332 3GJX GTP 0.000000001369 0.77534 16.2162
333 2VVG ADP 0.0000001264 0.67445 16.2162
334 4M9Q GNP 0.000000000006773 0.64473 16.2162
335 5DI3 GNP 0.000000000008839 0.64203 16.2162
336 2HF9 GSP 0.00000002292 0.58148 16.2162
337 3DEF GDP 0.0000007275 0.53365 16.2162
338 5LTJ ADP 0.00008993 0.50669 16.2162
339 1H65 GDP 0.000002131 0.47423 16.2162
340 1B7T ADP 0.00006858 0.46556 16.2162
341 1KK8 BEF ADP 0.00004627 0.44946 16.2162
342 1FNN ADP 0.0001546 0.42661 16.2162
343 5HGZ ACO 0.01414 0.41694 16.2162
344 4PJ3 ANP 0.001254 0.4123 16.2162
345 1MKY GDP 0.000000000000164 0.87509 16.4179
346 2OM2 GDP 0.0000000008457 0.60427 16.6667
347 1UPT GTP 0.0000000002932 0.59287 16.6667
348 4RZ3 ADP 0.00003101 0.5377 17.2881
349 3EWA ANP 0.00005018 0.49675 17.3913
350 3PQC GDP 0.000000001943 0.65192 17.4359
351 1CXZ GSP 0.000000004162 0.56319 17.4419
352 3EC1 GDP 0.00000000001686 0.75948 18.209
353 3WYG GTP 0.000000001031 0.52415 18.4211
354 3BC1 GNP 0.000000000149 0.56538 18.4615
355 5WDR GNP 0.0000000003479 0.80561 18.7134
356 4CVN ADP 0.000006485 0.56346 18.8482
357 4D0G GTP 0.00000000002104 0.85329 18.9189
358 1Z0F GDP 0.000000000005885 0.77665 18.9189
359 5CK5 GDP 0.000000001288 0.73032 18.9189
360 1T5C ADP 0.0000002011 0.66632 18.9189
361 2BCG GDP 0.00000000003947 0.65439 18.9189
362 1Z0K GTP 0.00000000008009 0.59738 18.9189
363 3RAB GNP 0.0000000000212 0.58471 18.9189
364 1RRC ADP 0.000006493 0.57806 18.9189
365 1NRJ GTP 0.0000000109 0.5723 18.9189
366 2BME GNP 0.0000000001396 0.56468 18.9189
367 1YZN GNP 0.0000000001666 0.55106 18.9189
368 1XMV ADP 0.00001786 0.50108 18.9189
369 1QF5 RPL 0.004478 0.49618 18.9189
370 1G6O ADP 0.0000429 0.47276 18.9189
371 5XDR ADP 0.0003993 0.44702 18.9189
372 2JLR ANP 0.0001412 0.44332 19.1045
373 1ZD9 GDP 0.0000000002388 0.63133 19.6809
374 2IXE ATP 0.0001143 0.40898 20.2952
375 5L3S GNP 0.0000005727 0.63709 21.6216
376 5L3W GDP 0.0000009709 0.60506 21.6216
377 4XSH GSP 0.000000002926 0.59182 21.6216
378 2OG2 MLI 0.00001167 0.58744 21.6216
379 3B9Q MLI 0.00001275 0.57096 21.6216
380 2KIN ADP 0.00000008154 0.56056 21.6216
381 5IRN ADP 0.000009289 0.56052 21.6216
382 1HTW ADP 0.000004788 0.52833 21.6216
383 1V8K ANP 0.0000141 0.52201 21.6216
384 2DPY ADP 0.00009884 0.5057 21.6216
385 2QZ4 ADP 0.00003204 0.48148 21.6216
386 5L3R GCP 0.0000006047 0.47587 21.6216
387 3TBK ANP 0.0007575 0.46252 21.6216
388 2D7D ADP 0.001248 0.43729 21.6216
389 2ZTS ADP 0.00008607 0.42977 21.6216
390 2ZJ5 ADP 0.01561 0.40148 21.6216
391 3NKV GNP 0.0000000001168 0.56491 21.7143
392 1LFD GNP 0.0000000001704 0.56038 21.8391
393 1Z0J GTP 0.0000000001326 0.5525 22.0339
394 2W83 GTP 0.00000000006508 0.60264 22.0779
395 1X1R GDP 0.0000000004116 0.53894 24.1573
396 3T1O GDP 0.0000000001016 0.70511 24.3243
397 2J0V GDP 0.000000000595 0.6916 24.3243
398 1BG2 ADP 0.00000006627 0.6913 24.3243
399 3T12 GDP ALF 0.0000000001622 0.60571 24.3243
400 4U5X GNP 0.000000003181 0.58839 24.3243
401 5MVR ADP 0.000003606 0.57045 24.3243
402 2Y65 ADP 0.0000002665 0.56329 24.3243
403 4D81 ADP 0.00003966 0.52973 24.3243
404 3P4X ADP 0.00006603 0.50668 24.3243
405 2PL3 ADP 0.0004304 0.46801 24.3243
406 2VF7 ADP 0.0001423 0.46501 24.3243
407 3FVQ ATP 0.0001744 0.41322 24.3243
408 1K6M AGS 0.00007237 0.41191 24.3243
409 4KAX GTP 0.0000000000297 0.62607 25.4658
410 2W58 ADP 0.000003473 0.59674 27.027
411 5IFS ADP 0.00004701 0.52328 27.027
412 1G3Q ADP 0.000006673 0.52278 27.027
413 4JLV ADP 0.0001183 0.49465 27.027
414 1R6B ADP 0.0000489 0.48669 27.027
415 1IHU AF3 0.000002092 0.46897 27.027
416 5FTB ANP 0.0000801 0.46344 27.027
417 1IHU ADP 0.000002354 0.45819 27.027
418 3VX3 ADP 0.00009183 0.439 27.027
419 2ZPA ADP 0.0001193 0.42992 27.027
420 5FHD ADP ALF 0.00007627 0.4236 27.027
421 5J1S ATP 0.00009243 0.40601 27.027
422 3CH5 GDP 0.00000000001837 0.75725 28.8462
423 3TK1 GDP 0.000000000004858 0.8625 29.7297
424 2EW1 GNP 0.0000000001482 0.59104 29.7297
425 4V0K GDP 0.00000000008299 0.58681 29.7297
426 1Y63 ADP 0.000003425 0.55024 29.7297
427 5TSH ANP 0.00002135 0.53348 29.7297
428 4PFO ADP 0.00009202 0.52785 29.7297
429 2VB6 ADP BEF 0.00009875 0.52223 29.7297
430 3B5J 12D 0.00005053 0.51993 29.7297
431 4TTQ ATP 0.00003302 0.50832 29.7297
432 1ION ADP 0.0000206 0.49021 29.7297
433 5TSH ADP 0.00005055 0.4887 29.7297
434 5N69 ADP 0.00005817 0.45687 29.7297
435 4HDQ GNP 0.000000001199 0.5312 30.7692
436 1FQJ GDP 0.0000000007355 0.57689 30.9524
437 3A1S GDP 0.0000000373 0.62395 32.4324
438 3E70 GDP 0.0000006076 0.56978 32.4324
439 1WDT GTP 0.00000007166 0.54689 32.4324
440 4NON GDP 0.0000000005578 0.52924 32.4324
441 5M7P ADP 0.00007646 0.52095 32.4324
442 4IHQ ADP 0.0001058 0.49696 32.4324
443 5WRJ A3P 0.0007007 0.48139 32.4324
444 5WRI A3P 0.0007697 0.47553 32.4324
445 2WJG GDP 0.00000000000888 0.80073 35.1351
446 2WJH GDP 0.00000000003419 0.74836 35.1351
447 1YRB GDP 0.00000000001415 0.71051 35.1351
448 1TQ4 GDP 0.0000000007723 0.59672 35.1351
449 2WJH FLC 0.0000001227 0.58219 35.1351
450 4LYA ATP 0.000004061 0.53154 35.1351
451 3ZIA ATP 0.000005887 0.52417 35.1351
452 3ZIA ADP 0.000006116 0.4964 35.1351
453 5M04 GDP 0.00000000000525 0.8438 37.8378
454 4R98 GNH 0.0000000009911 0.74086 37.8378
455 2WIC GNP 0.0000000002935 0.709 37.8378
456 4TMZ GSP 0.00000000002505 0.6133 37.8378
457 1W0J ADP 0.000002675 0.58693 37.8378
458 2V7Q ATP 0.000002461 0.52593 37.8378
459 1W0J ADP BEF 0.0001205 0.51118 37.8378
460 2V7Q ADP 0.00009285 0.48566 37.8378
461 1OFH ADP 0.00006173 0.47106 37.8378
462 2CK3 ANP 0.0001419 0.42645 37.8378
463 2CK3 ADP 0.0001636 0.4013 37.8378
464 2WHX ADP 0.00001825 0.54897 40.5405
465 3Q9L ATP 0.0001086 0.44047 40.5405
466 4V03 ADP 0.000006769 0.56413 43.2432
467 4HI0 GDP 0.00000001803 0.56305 43.2432
468 1Y3A GDP 0.000000001487 0.57032 50
Pocket No.: 2; Query (leader) PDB : 2HCJ; Ligand: GLV; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2hcj.bio1) has 2 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2HCJ; Ligand: TAC; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2hcj.bio1) has 5 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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