Receptor
PDB id Resolution Class Description Source Keywords
2HF9 1.9 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF HYPB FROM METHANOCALDOCOCCUS JANNASCHII IN THE TRIPHOSPHATE FORM METHANOCALDOCOCCUS JANNASCHII ALPHA AND BETA PROTEIN P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE HYDROLASE METAL BINDING PROTEIN
Ref.: STRUCTURAL INSIGHTS INTO HYPB, A GTP-BINDING PROTEIN THAT REGULATES METAL BINDING. J.BIOL.CHEM. V. 281 27492 2006
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GSP A:300;
B:300;
Valid;
Valid;
none;
none;
Kd = 3.4 uM
539.246 C10 H16 N5 O13 P3 S c1nc2...
MG A:301;
B:301;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
ZN A:302;
B:302;
Part of Protein;
Part of Protein;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2HF9 1.9 Å EC: 7.-.-.- CRYSTAL STRUCTURE OF HYPB FROM METHANOCALDOCOCCUS JANNASCHII IN THE TRIPHOSPHATE FORM METHANOCALDOCOCCUS JANNASCHII ALPHA AND BETA PROTEIN P-LOOP CONTAINING NUCLEOSIDE TRIPHOSPHATE HYDROLASE HYDROLASE METAL BINDING PROTEIN
Ref.: STRUCTURAL INSIGHTS INTO HYPB, A GTP-BINDING PROTEIN THAT REGULATES METAL BINDING. J.BIOL.CHEM. V. 281 27492 2006
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 2HF8 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
2 2HF9 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 217 families.
1 2HF8 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
2 2HF9 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 2HF8 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
2 2HF9 Kd = 3.4 uM GSP C10 H16 N5 O13 P3 S c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GSP; Similar ligands found: 132
No: Ligand ECFP6 Tc MDL keys Tc
1 GSP 1 1
2 GP3 0.897436 0.925
3 GTP 0.853659 0.948718
4 GNH 0.829268 0.936709
5 GDP 0.817073 0.948718
6 G1R 0.8 0.936709
7 GCP 0.77907 0.925
8 GNP 0.770115 0.925
9 GMV 0.767442 0.925
10 5GP 0.756098 0.935897
11 G 0.756098 0.935897
12 G2R 0.747253 0.91358
13 GKE 0.744681 0.91358
14 GDD 0.744681 0.91358
15 GDC 0.744681 0.91358
16 GPG 0.73913 0.91358
17 GTG 0.736842 0.891566
18 G3A 0.729167 0.925
19 G5P 0.721649 0.925
20 GDR 0.71875 0.91358
21 GFB 0.71875 0.91358
22 GAV 0.714286 0.987179
23 GP2 0.712644 0.91358
24 6CK 0.71134 0.891566
25 Y9Z 0.708333 0.860465
26 JB2 0.69697 0.91358
27 GKD 0.69697 0.91358
28 GDP MG 0.696629 0.878049
29 G2P 0.692308 0.91358
30 GDX 0.69 0.925
31 GPD 0.69 0.880952
32 GDP BEF 0.688889 0.857143
33 GCP G 0.677419 0.888889
34 ALF 5GP 0.67033 0.847059
35 0O2 0.666667 0.935897
36 GTP MG 0.666667 0.878049
37 BEF GDP 0.666667 0.847059
38 YGP 0.663265 0.858824
39 JB3 0.657143 0.902439
40 GDP ALF 0.645833 0.847059
41 GDP AF3 0.645833 0.847059
42 G G 0.642857 0.888889
43 GMP 0.641975 0.835443
44 G3D 0.638298 0.935897
45 NGD 0.635514 0.91358
46 2MD 0.633027 0.894118
47 CAG 0.630631 0.840909
48 G4P 0.625 0.935897
49 U2G 0.62037 0.891566
50 FEG 0.62037 0.83908
51 MGD 0.616071 0.894118
52 ZGP 0.614679 0.872093
53 CG2 0.609091 0.891566
54 TPG 0.598291 0.804348
55 3GP 0.595506 0.898734
56 GDP 7MG 0.590476 0.86747
57 GH3 0.581633 0.924051
58 MD1 0.581197 0.894118
59 PGD 0.581197 0.926829
60 2GP 0.577778 0.911392
61 DGT 0.561224 0.878049
62 DBG 0.558333 0.902439
63 G1G 0.550847 0.880952
64 SAP 0.547368 0.924051
65 AGS 0.547368 0.924051
66 FE9 0.546219 0.8
67 G4M 0.539062 0.840909
68 U A G G 0.538462 0.888889
69 G A A A 0.529915 0.878049
70 MGP 0.525253 0.91358
71 GPX 0.524272 0.898734
72 BGO 0.521739 0.879518
73 DGI 0.520408 0.878049
74 6G0 0.52 0.91358
75 I2C FE2 CMO CMO 0.516667 0.774194
76 IDP 0.515464 0.923077
77 GGM 0.508475 0.858824
78 G1R G1R 0.508065 0.879518
79 PGD O 0.504 0.875
80 G G U 0.5 0.888889
81 GTA 0.486726 0.891566
82 P2G 0.484536 0.839506
83 GPC 0.483607 0.83908
84 G C 0.483333 0.857143
85 P1G 0.474747 0.829268
86 DG 0.474227 0.865854
87 DGP 0.474227 0.865854
88 BA3 0.46875 0.85
89 AP5 0.463918 0.85
90 B4P 0.463918 0.85
91 IMP 0.463918 0.910256
92 G2Q 0.462963 0.91358
93 G G G RPC 0.459016 0.833333
94 APC G U 0.456 0.843373
95 U G A 0.452555 0.847059
96 ATP 0.45 0.873418
97 G G G C 0.448819 0.869048
98 A2D 0.447917 0.85
99 5FA 0.445545 0.873418
100 AQP 0.445545 0.873418
101 A G C C 0.445312 0.86747
102 G7M 0.444444 0.901235
103 G U34 0.442623 0.847059
104 01G 0.442478 0.860465
105 ITT 0.44 0.825
106 SGP 0.44 0.876543
107 G C C C 0.431818 0.879518
108 AN2 0.43 0.8625
109 DG DG 0.428571 0.825581
110 A4P 0.42623 0.829545
111 UCG 0.424242 0.86747
112 C2E 0.423077 0.875
113 PCG 0.423077 0.886076
114 35G 0.423077 0.886076
115 MGO 0.420561 0.823529
116 ADP 0.42 0.873418
117 ANP 0.419048 0.851852
118 5GP 5GP 0.419048 0.839506
119 ADQ 0.418182 0.829268
120 APR 0.417476 0.85
121 AR6 0.417476 0.85
122 7DT 0.417476 0.860759
123 A G U 0.414286 0.847059
124 AD9 0.413462 0.851852
125 UP5 0.413223 0.831325
126 A22 0.412844 0.8625
127 25L 0.412281 0.8625
128 M33 0.411765 0.839506
129 JBT 0.410405 0.783505
130 ACP 0.407767 0.851852
131 ACQ 0.40566 0.851852
132 A1R 0.405405 0.8
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2HF9; Ligand: GSP; Similar sites found: 534
This union binding pocket(no: 1) in the query (biounit: 2hf9.bio2) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1R4A GNP 0.00000008743 0.63063 None
2 1VG8 GNP 0.0000001625 0.6237 None
3 1VG1 GDP 0.00000002168 0.60698 None
4 3AQ4 GDP 0.00000002965 0.59956 None
5 1EK0 GNP 0.000001547 0.57705 None
6 4WOP CTP 0.00001808 0.51741 0.888889
7 2OFW ADX 0.001349 0.43907 0.961538
8 2QG6 NMN 0.00002294 0.52828 1.00503
9 2PEZ DAT 0.0001272 0.50112 1.11732
10 4TMK T5A 0.002512 0.44244 1.40845
11 5KSP GDP 0.000002176 0.59289 1.57895
12 1ION ADP 0.00001662 0.49874 1.76991
13 1KY3 GDP 0.000000628 0.56888 2.1978
14 1FZQ GDP 0.000000182 0.56116 2.20994
15 3DZD ADP 0.00009898 0.47518 2.21239
16 2IXE ATP 0.0005635 0.45587 2.21239
17 2VVG ADP 0.000002681 0.44757 2.21239
18 1XP8 AGS 0.001439 0.40176 2.21239
19 5EE5 GTP 0.0000007307 0.53298 2.34742
20 1M7G ADX 0.00006253 0.51374 2.36967
21 1M7G ADP 0.0001024 0.50049 2.36967
22 1M7G AV2 0.00000299 0.49698 2.36967
23 3QXC ATP 0.0000188 0.53022 2.47934
24 1VG0 GDP 0.00000005203 0.61429 2.65487
25 1VG9 GDP 0.00000001951 0.60887 2.65487
26 2WKQ GTP 0.0000009571 0.52668 2.65487
27 3BOS CDP 0.00004349 0.46399 2.65487
28 4IOK ADP 0.0008979 0.45579 2.65487
29 4IOK XPO 0.0007794 0.45342 2.65487
30 1D2N ANP 0.000683 0.45012 2.65487
31 1XCL SAH 0.002949 0.43921 2.65487
32 3DKP ADP 0.0002751 0.43729 2.65487
33 4WEI GLC GAL 0.01475 0.42975 2.65487
34 2ZR9 DTP 0.0006112 0.42316 2.65487
35 5I0H ADP BEF 0.0005916 0.41594 2.65487
36 4KBF AMP 0.0009395 0.4115 2.65487
37 2Z9I GLY ALA THR VAL 0.01644 0.40718 2.65487
38 3TBK ANP 0.001372 0.4018 2.65487
39 3SBD GNP 0.00002388 0.4924 2.6738
40 1Y63 ADP 0.000006938 0.49457 2.71739
41 2QQ0 TMP 0.00373 0.43317 2.71739
42 2QQ0 ANP 0.003756 0.43303 2.71739
43 2QQ0 THM 0.003283 0.43303 2.71739
44 4TTQ ATP 0.00001661 0.48175 2.7907
45 1Z0A GDP 0.00000001604 0.62508 2.87356
46 1G16 GDP 0.0000004434 0.59364 2.94118
47 2NCD ADP 0.00000845 0.57989 3.09735
48 1D2E GDP 0.000000487 0.57367 3.09735
49 1G7S GDP 0.0000002171 0.56809 3.09735
50 5KSZ GCP 0.00001524 0.54513 3.09735
51 3Q9L ATP 0.00005315 0.49407 3.09735
52 2BEK ATP 0.0003427 0.48811 3.09735
53 2CHG ANP 0.0002038 0.46863 3.09735
54 4PJ3 ANP 0.000538 0.4672 3.09735
55 2OZE AGS 0.0003749 0.45941 3.09735
56 1OYY AGS 0.000107 0.45353 3.09735
57 4QOS ADP 0.0002471 0.45223 3.09735
58 4IHQ ADP 0.0002237 0.43195 3.09735
59 4V03 ADP 0.00006654 0.42286 3.09735
60 1OIX GDP 0.000001442 0.54118 3.14136
61 3GJ0 GDP 0.00000007312 0.57814 3.16742
62 3GJ3 GDP 0.00000008514 0.57576 3.16742
63 3CH5 GDP 0.00000006787 0.58924 3.24074
64 4YLG GDP 0.0000007098 0.50983 3.46821
65 2HV8 GTP 0.0000001947 0.61764 3.48837
66 2FJU GSP 0.000001241 0.57106 3.53982
67 2ZFI ADP 0.00001119 0.55141 3.53982
68 4PPF FLC 0.00006424 0.54122 3.53982
69 5FTB ANP 0.0000471 0.52204 3.53982
70 1CR1 TTP 0.0001936 0.47428 3.53982
71 3VX3 ADP 0.000242 0.46776 3.53982
72 3EZ2 ADP 0.00009673 0.44048 3.53982
73 2PZE ATP 0.00001079 0.43987 3.53982
74 5FHD ADP ALF 0.001825 0.43073 3.53982
75 1WMA AB3 0.008861 0.42831 3.53982
76 1G6H ADP 0.00001314 0.42614 3.53982
77 4NU0 AP5 0.0004017 0.48486 3.68664
78 2BCG GDP 0.0000002068 0.60232 3.8835
79 2JAQ DCP 0.004534 0.4174 3.90244
80 3E5H GNP 0.000001024 0.58513 3.93258
81 1WA5 GTP 0.00000004794 0.65736 3.9823
82 2C77 GNP 0.00000002083 0.64939 3.9823
83 2C78 GNP 0.00000004218 0.63899 3.9823
84 1SKQ GDP 0.000000004235 0.60392 3.9823
85 1MKY GDP 0.00000003065 0.58814 3.9823
86 3ZS9 ADP ALF 0.00001613 0.53323 3.9823
87 4ZKD GDP 0.000007562 0.51454 3.9823
88 1IWE IMP 0.0007805 0.51128 3.9823
89 3ZFD ANP 0.00002221 0.49423 3.9823
90 5FG3 GDP 0.000000122 0.49327 3.9823
91 2CE7 ADP 0.00002644 0.49095 3.9823
92 2Q2Y ADP 0.0003698 0.48905 3.9823
93 2Q2Y MKR 0.0003732 0.48763 3.9823
94 4LYA ATP 0.0007311 0.47103 3.9823
95 4XVU ATP 0.0002129 0.46239 3.9823
96 1L2T ATP 0.0005095 0.4617 3.9823
97 1RRC ADP 0.000006953 0.44953 3.9823
98 4XTR ATP 0.0001658 0.4483 3.9823
99 2WOJ ADP ALF 0.0002343 0.44607 3.9823
100 1E2K TMC 0.003944 0.44027 3.9823
101 3QVV A3P 0.003265 0.43962 3.9823
102 3QKT ANP 0.002044 0.43462 3.9823
103 1JJ7 ADP 0.000005826 0.4329 3.9823
104 4XTR ADP 0.0001789 0.42903 3.9823
105 3B7G ANP 0.0007159 0.4285 3.9823
106 4IEE AGS 0.0005431 0.4219 3.9823
107 3QVV 3QV 0.01488 0.41472 3.9823
108 2AWN ADP 0.000007522 0.41405 3.9823
109 1Z08 GNP 0.0000005253 0.59309 4.11765
110 3TMK T5A 0.0001445 0.49365 4.16667
111 1KAO GDP 0.0000002235 0.59762 4.19162
112 5BQ5 ADP BEF 0.0001418 0.49948 4.2328
113 1KSH GDP 0.0000002037 0.60569 4.30108
114 1YZN GNP 0.0000002325 0.61665 4.32432
115 1GWN GTP 0.0000005417 0.58695 4.39024
116 2BVN GNP 0.00000006948 0.60994 4.42478
117 1D8T GDP 0.00000005441 0.57998 4.42478
118 1QF5 GDP 0.0001344 0.52027 4.42478
119 4YMU ATP 0.0002596 0.50504 4.42478
120 1P9B GDP 0.00006713 0.48966 4.42478
121 5LB3 ADP 0.0006712 0.48413 4.42478
122 2QEN ADP 0.0003036 0.46109 4.42478
123 1G41 ADP 0.0001694 0.45966 4.42478
124 4GBM A3P 0.0009437 0.44785 4.42478
125 5I34 GDP 0.00001292 0.44141 4.42478
126 2ZPT A3P 0.02615 0.41166 4.42478
127 3IUY AMP 0.003262 0.40113 4.42478
128 1Z0F GDP 0.00000001418 0.61692 4.46927
129 1X1R GDP 0.0000001759 0.62214 4.49438
130 3UIE ANP 0.00008867 0.4696 4.5
131 4D0G GTP 0.0000006753 0.53462 4.57143
132 4M7V RAR 0.01791 0.41351 4.57143
133 3TNF GNP 0.00000008842 0.63815 4.5977
134 4LHW GNP 0.0000001017 0.63035 4.5977
135 1ZIN AP5 0.0004737 0.48395 4.60829
136 2CJW GDP 0.000000004428 0.61922 4.6875
137 3H86 AP5 0.005327 0.42847 4.6875
138 3Q72 GNP 0.0000000006741 0.63825 4.81928
139 3CX8 GSP 0.00000004082 0.6559 4.86726
140 1ZCB GDP 0.00000006481 0.63918 4.86726
141 3AB3 GDP 0.00000005867 0.62954 4.86726
142 3CNL GNP 0.000000006462 0.59608 4.86726
143 3VMF GTP 0.0000008696 0.58833 4.86726
144 1WDT GTP 0.0000005193 0.56861 4.86726
145 4NE2 ADP 0.00009729 0.50958 4.86726
146 4NE2 SH2 0.0001122 0.50958 4.86726
147 1V8K ANP 0.000003524 0.50605 4.86726
148 5MZN ADP 0.0006857 0.48988 4.86726
149 1YTM ATP 0.0001423 0.48019 4.86726
150 1SQ5 ADP 0.00003892 0.47675 4.86726
151 1NJF AGS 0.0001957 0.47625 4.86726
152 4R43 GDP 0.0009674 0.47045 4.86726
153 1OS1 ATP 0.0005712 0.46636 4.86726
154 1OS1 PYR 0.000708 0.46365 4.86726
155 3RLF ANP 0.0006443 0.45525 4.86726
156 2IS6 ADP 0.0001153 0.4523 4.86726
157 1NJF ADP 0.0005491 0.45214 4.86726
158 4OHY ANP 0.0008778 0.4511 4.86726
159 1SVM ATP 0.003812 0.44784 4.86726
160 1BG2 ADP 0.000002319 0.4475 4.86726
161 5IFS ADP 0.00003211 0.43644 4.86726
162 1M7B GTP 0.0000005398 0.55608 4.8913
163 3N5C GDP 0.000000008971 0.69968 4.93827
164 3ZQ6 ADP ALF 0.00001203 0.539 4.93827
165 1MR3 G3D 0.000000127 0.57657 4.97238
166 3IIJ ADP 0.000006117 0.4993 5
167 2F9L GDP 0.0000001014 0.62497 5.02513
168 4BAS GNP 0.0000001851 0.61048 5.02513
169 1S3G AP5 0.0002211 0.49964 5.06912
170 1W4R TTP 0.00671 0.41597 5.12821
171 4OI4 ATP 0.0002745 0.47179 5.21739
172 1OIV GDP 0.000001087 0.54609 5.2356
173 5KUT GDP 0.0000002131 0.5086 5.29101
174 1SVK ALF GDP 0.00000002091 0.67162 5.30973
175 1BH2 GSP 0.00000004355 0.65461 5.30973
176 1TAD GDP 0.00000006038 0.64813 5.30973
177 1AZT GSP 0.00000009668 0.63878 5.30973
178 2OM2 GDP 0.00000003764 0.63805 5.30973
179 1Y3A GDP 0.0000001335 0.61964 5.30973
180 1FQJ GDP 0.000000263 0.6065 5.30973
181 1FQK GDP 0.0000003841 0.59916 5.30973
182 1DAR GDP 0.0000000227 0.59379 5.30973
183 1JWY GDP 0.0000004032 0.57645 5.30973
184 4DCT GDP 0.0000002676 0.56498 5.30973
185 4WZ6 ATP 0.00003639 0.5624 5.30973
186 1TAD ALF 0.000001347 0.5148 5.30973
187 5IRR GSP 0.00002825 0.50383 5.30973
188 5M04 GDP 0.0000001803 0.48841 5.30973
189 2B8W ALF 5GP 0.0002939 0.47243 5.30973
190 1K6M AGS 0.0002667 0.47235 5.30973
191 1F5N GNP 0.0005327 0.46442 5.30973
192 3H4S ADP 0.00000438 0.45335 5.30973
193 1JWY ADP 0.0001375 0.45264 5.30973
194 4FRZ ADP 0.00001685 0.45178 5.30973
195 3B5J 12D 0.00007104 0.43897 5.30973
196 1B0U ATP 0.001157 0.42928 5.30973
197 4A4Z ANP 0.0008877 0.41997 5.30973
198 2Z5F A3P 0.004369 0.41452 5.30973
199 5IRN ADP 0.0002958 0.40982 5.30973
200 4X1Z FUC GAL NDG 0.03398 0.40882 5.30973
201 1CS4 GSP 0.000000038 0.65485 5.33333
202 5N69 ADP 0.00009909 0.50106 5.52764
203 4MKF AP5 0.0002364 0.4995 5.52995
204 5JCZ GDP 0.00000177 0.56757 5.58659
205 4G5G GDP 0.00000003991 0.58408 5.75221
206 4P3Y GDP 0.00000001931 0.58328 5.75221
207 3U6B GDP 0.00000002093 0.58275 5.75221
208 3U6K GDP 0.00000004879 0.5823 5.75221
209 3MD0 GDP 0.00000002594 0.57958 5.75221
210 4RD0 GDP 0.0000006618 0.53469 5.75221
211 4XGU ADP 0.0000539 0.50752 5.75221
212 5JBQ GDP 0.00000008363 0.50471 5.75221
213 3KJI ADP 0.0001014 0.4748 5.75221
214 1FP6 ADP 0.0002548 0.4578 5.75221
215 2ZTS ADP 0.0005472 0.45221 5.75221
216 4GOX A3P 0.0009379 0.44797 5.75221
217 4HSE ADP 0.0001827 0.44725 5.75221
218 1IN4 ADP 0.0009535 0.44163 5.75221
219 4E03 ADP 0.00006618 0.46917 5.82524
220 3RAB GNP 0.000000392 0.60394 5.91716
221 3Q85 GNP 0.0000000285 0.59078 5.91716
222 1F2U ATP 0.003066 0.42996 6.04027
223 3GJX GTP 0.00000003986 0.65134 6.19469
224 2QTV GNP 0.00000003373 0.64919 6.19469
225 4PC3 GDP 0.0000001663 0.62893 6.19469
226 3PCR GTP 0.0000001121 0.5605 6.19469
227 4YDS ATP 0.00004931 0.54932 6.19469
228 2ODE ALF GDP 0.000001352 0.54902 6.19469
229 2CK3 ADP 0.0002593 0.47289 6.19469
230 1XKV ATP 0.0001188 0.46518 6.19469
231 2V7Q ADP 0.00003885 0.46402 6.19469
232 3A4M ADP 0.00001624 0.46145 6.19469
233 2CK3 ANP 0.0003691 0.45971 6.19469
234 1W0J ADP BEF 0.0003921 0.45856 6.19469
235 3COB ADP 0.000004657 0.45616 6.19469
236 1W0J ADP 0.0003005 0.4546 6.19469
237 2V7Q ATP 0.0002198 0.45346 6.19469
238 2XT3 ADP 0.000005871 0.45305 6.19469
239 1T5C ADP 0.000004685 0.44028 6.19469
240 4P32 ADP 0.001764 0.43386 6.19469
241 4AG5 ADP 0.00005493 0.43265 6.19469
242 1NRJ GTP 0.00000001012 0.66323 6.32911
243 4DSU GDP 0.0000001939 0.62022 6.34921
244 2GJ8 ALF GDP 0.00002503 0.48435 6.39535
245 3QBT GNP 0.0000001511 0.53677 6.42857
246 1NN5 ANP 0.0001584 0.49513 6.51163
247 4M9Q GNP 0.0000001779 0.61124 6.63717
248 1WF3 GNP 0.0000005488 0.59975 6.63717
249 5GOE GDP 0.000001385 0.59421 6.63717
250 3DEF GDP 0.00002178 0.50352 6.63717
251 2GDJ ANP 0.00003684 0.46668 6.63717
252 1W5T ANP 0.0004603 0.45769 6.63717
253 3FYH ADP 0.0006757 0.4562 6.63717
254 1W5T ADP 0.000541 0.45016 6.63717
255 2BIF SIN 0.00288 0.44989 6.63717
256 2BIF ANP 0.001738 0.44989 6.63717
257 5VGR GDP 0.001551 0.44173 6.63717
258 1XMV ADP 0.0003212 0.43937 6.63717
259 4RLQ 3SK 0.02287 0.41045 6.63717
260 2YOH WMJ 0.00005804 0.41149 6.66667
261 1DS6 GDP 0.0000001388 0.56375 6.77083
262 1KO8 6PG 0.0001312 0.47942 6.85714
263 5UQW GDP 0.000002236 0.52736 6.87831
264 2EW1 GNP 0.0000002036 0.61146 6.96517
265 1MH1 GNP 0.000005705 0.50921 6.98925
266 1G4U GDP 0.00000161 0.56323 7.06522
267 1PUJ GNP 0.00000003089 0.62397 7.07965
268 4TMZ GSP 0.0000001212 0.62151 7.07965
269 4NCN GTP 0.0000001933 0.61246 7.07965
270 1IHU ADP 0.00007298 0.49746 7.07965
271 1IHU AF3 0.0001712 0.47884 7.07965
272 3FVQ ATP 0.0004366 0.4587 7.07965
273 4JLV ADP 0.00009175 0.44187 7.07965
274 4PFO ADP 0.003183 0.40735 7.07965
275 2VB6 ADP BEF 0.00227 0.40432 7.07965
276 5E95 GDP 0.0000006418 0.59428 7.14286
277 1XEX ATP 0.0003799 0.46928 7.14286
278 2D7C GTP 0.00000005481 0.64246 7.18563
279 3REF GDP 0.0000008972 0.58006 7.2165
280 1WQ1 GDP 0.0000002597 0.60674 7.22892
281 1CLU DBG 0.000004358 0.54863 7.22892
282 1XX6 ADP 0.000996 0.40871 7.32984
283 1VHT BA3 0.0000994 0.46824 7.33945
284 1HE1 GDP 0.000002698 0.52692 7.40741
285 1HE1 AF3 0.01553 0.40928 7.40741
286 2WJG GDP 0.00000001433 0.68994 7.44681
287 5JCP GDP ALF 0.0000002863 0.61009 7.52212
288 1R0X ATP 0.00001675 0.46727 7.52212
289 2ZE7 DST 0.0005814 0.4627 7.52212
290 1G6O ADP 0.0001499 0.45966 7.52212
291 3LRE ADP 0.000008636 0.43661 7.52212
292 5K5Z ANP 0.0014 0.42494 7.52212
293 2ZE7 AMP 0.004118 0.42258 7.52212
294 2FNA ADP 0.0008635 0.42008 7.52212
295 1QHG ATP 0.005679 0.40147 7.52212
296 1QHH ATP 0.003063 0.4009 7.52212
297 4KFU ACP 0.00003675 0.44836 7.54717
298 5DI3 GNP 0.0000007051 0.57175 7.56757
299 1YVD GNP 0.0000001706 0.62023 7.69231
300 1QF9 C5P 0.00009957 0.51202 7.73196
301 1YZG GDP 0.00000003601 0.59705 7.82123
302 2UZI GTP 0.00000007513 0.63628 7.83133
303 1E96 GTP 0.000001669 0.57557 7.88177
304 3WYA GDP 0.00000001432 0.60156 7.9646
305 3WXM GTP 0.0000006787 0.59318 7.9646
306 3WY9 GDP 0.00000002489 0.58286 7.9646
307 5L3V GDP 0.000007588 0.5594 7.9646
308 1G7C 5GP 0.0000007457 0.53668 7.9646
309 4KVA GTP 0.00005177 0.52955 7.9646
310 1UJ2 C5P 0.00006269 0.50652 7.9646
311 1UJ2 ADP 0.00008228 0.50117 7.9646
312 2DPY ADP 0.000252 0.49979 7.9646
313 4CVN ADP 0.00006575 0.44113 7.9646
314 4RZ3 ADP 0.0006235 0.40662 7.9646
315 1ZD9 GDP 0.000000005103 0.67283 7.97872
316 1DAK DPU 0.00001739 0.55477 8.03571
317 3GJ8 GDP 0.00000009562 0.64047 8.1448
318 3GJ5 GDP 0.0000001089 0.58192 8.1448
319 4QM7 GTP 0.00003132 0.47174 8.18713
320 1JJV ATP 0.000003734 0.47424 8.25243
321 4KAX GTP 0.00000005458 0.63402 8.28402
322 3FKQ ATP 0.0001254 0.47782 8.31099
323 1ZUI SKM 0.0001843 0.49807 8.33333
324 2XTZ GSP 0.00000004211 0.64762 8.40708
325 1G3Q ADP 0.000008422 0.50079 8.40708
326 1OE0 TTP 0.0003812 0.47101 8.40708
327 2JLR ANP 0.0003934 0.44947 8.40708
328 1P72 ADP 0.002641 0.44013 8.40708
329 2WHX ADP 0.00006594 0.4289 8.40708
330 1G3M PCQ 0.01126 0.41757 8.40708
331 5E58 CPZ 0.0219 0.41178 8.40708
332 1M2O GNP 0.00000009098 0.63253 8.42105
333 1O3Y GTP 0.00000001456 0.66259 8.43373
334 2J59 GTP 0.00000002291 0.6538 8.43373
335 1J2J GTP 0.00000002895 0.64927 8.43373
336 2GCO GNP 0.0000001431 0.60607 8.45771
337 2GCN GDP 0.0000007592 0.58328 8.45771
338 3CPJ GDP 0.00000007225 0.6086 8.52018
339 5G41 AP5 0.0006613 0.45888 8.52018
340 5H67 ATP 0.003072 0.44094 8.54271
341 2RGX AP5 0.0001723 0.50725 8.73786
342 4MKG AP5 0.0002088 0.50083 8.75576
343 1OW3 GDP 0.000002098 0.49452 8.80829
344 1IBR GNP 0.0000000502 0.64681 8.84956
345 2G77 GDP 0.00000007213 0.61903 8.84956
346 1YRB GDP 0.0000001062 0.60177 8.84956
347 4LX0 BEF GDP 0.000001794 0.53967 8.84956
348 3IO3 ADP 0.0000181 0.51715 8.84956
349 4ZG4 VO4 ADP 0.0004824 0.43013 8.84956
350 1UKZ ADP 0.0005521 0.47304 8.86699
351 2W2X GSP 0.0000002599 0.60102 8.87097
352 1LFD GNP 0.0000001606 0.62141 8.98204
353 3LXR GDP 0.0000002509 0.61194 9.18919
354 4D0N GDP 0.00000003525 0.58788 9.18919
355 5HPY GDP 0.000002977 0.48975 9.18919
356 3BC1 GNP 0.000000251 0.61267 9.23077
357 1SVI GDP 0.00000007932 0.56465 9.23077
358 1KMQ GNP 0.0000003872 0.599 9.23913
359 2C5L GTP 0.00000004229 0.65018 9.24856
360 3KTA AP5 0.0002294 0.4593 9.24856
361 3FB4 AP5 0.0002832 0.49454 9.25926
362 3WYG GTP 0.0000000192 0.66834 9.29204
363 3WYF GTP 0.00000002434 0.66365 9.29204
364 3M1I GTP 0.00000002203 0.66302 9.29204
365 4HAT GNP 0.00000003883 0.65442 9.29204
366 2WIC GNP 0.000000001936 0.64679 9.29204
367 4NON GDP 0.0000002687 0.61618 9.29204
368 4J0Q GDP 0.000000004782 0.60176 9.29204
369 4GOJ GNP 0.0000003394 0.59879 9.29204
370 3T34 GDP 0.000001683 0.57052 9.29204
371 5UWT GNP 0.0000004063 0.56563 9.29204
372 5UWI GNP 0.000000447 0.56395 9.29204
373 5UWP GNP 0.0000005443 0.56284 9.29204
374 5UWR GNP 0.0000005011 0.56196 9.29204
375 5UWH GNP 0.000000362 0.55522 9.29204
376 5UWU GNP 0.0000004246 0.55259 9.29204
377 5UWJ GNP 0.0000004336 0.55223 9.29204
378 5DIF GNP 0.0000004831 0.55038 9.29204
379 5UWO GNP 0.0000005019 0.54979 9.29204
380 5DHF GNP 0.0000005135 0.54944 9.29204
381 5UWQ GNP 0.0000005176 0.54931 9.29204
382 5UWW GNP 0.0000005307 0.54889 9.29204
383 5DI9 GNP 0.0000005037 0.54052 9.29204
384 5UWS GNP 0.000000534 0.5396 9.29204
385 1FNN ADP 0.0001058 0.48351 9.29204
386 4R98 GNH 0.000001474 0.47406 9.29204
387 2ZPA ADP 0.0007114 0.44721 9.29204
388 1YQT ADP 0.0000943 0.42299 9.29204
389 3NHB ADP 0.0001363 0.41789 9.29204
390 1CXZ GSP 0.0000001482 0.61476 9.34066
391 4K81 GTP 0.0000002325 0.61905 9.35672
392 4XSH GSP 0.0000006857 0.58575 9.49721
393 4HDQ GNP 0.0000001437 0.62612 9.58084
394 4HDO GNP 0.0000001476 0.62559 9.58084
395 3X1Z GNP 0.000001734 0.52032 9.58084
396 1F6B GDP 0.0000000341 0.59847 9.59596
397 1TX4 ALF GDP 0.0000003561 0.60063 9.60452
398 3TKL GTP 0.0000001026 0.62752 9.69388
399 1JI0 ATP 0.00004366 0.44645 9.73451
400 4IDN GNP 0.001267 0.43381 9.73451
401 2D7D ADP 0.001093 0.41612 9.73451
402 4KVG GTP 0.00000009261 0.63219 10.119
403 2CBZ ATP 0.0000006492 0.65587 10.177
404 3A1S GDP 0.000001971 0.53199 10.177
405 5CK5 GDP 0.00000001755 0.51716 10.177
406 3FWY ADP 0.0001217 0.4784 10.177
407 4PX9 ADP 0.0009344 0.47685 10.177
408 1OXV ANP 0.00009683 0.442 10.177
409 5XDR ADP 0.004747 0.43181 10.177
410 2BME GNP 0.00000009014 0.63272 10.2151
411 4BQS ADP 0.00001646 0.54338 10.2273
412 2FH5 GTP 0.00000003206 0.64113 10.2703
413 3NKV GNP 0.00000007558 0.63617 10.2857
414 1RYH GNP 0.0000001289 0.58856 10.3448
415 1RE0 GDP 0.00000001429 0.58689 10.4072
416 2A5J GDP 0.00000003692 0.61045 10.4712
417 3SFV GDP 0.0000001681 0.60938 10.4972
418 1GOJ ADP 0.000001863 0.62221 10.6195
419 4P4T GDP 0.000001874 0.56034 10.6195
420 1W7J ADP BEF 0.0001932 0.46965 10.6195
421 1R6B ADP 0.0001845 0.45142 10.6195
422 4FCW ADP 0.0002266 0.44766 10.6195
423 1F9V ADP 0.00002543 0.44597 10.6195
424 1XTQ GDP 0.0000006412 0.58923 10.7345
425 3W5J GDP 0.0000001455 0.50513 10.7843
426 2WJH GDP 0.0000000125 0.61903 10.8434
427 2WJH FLC 0.000001143 0.54985 10.8434
428 2A5F GTP 0.00000002925 0.65197 10.8571
429 3ZIA ATP 0.0001289 0.45592 10.8696
430 3ZIA ADP 0.0003778 0.45038 10.8696
431 1B7T ADP 0.0006404 0.43429 10.8974
432 1OFH ADP 0.00005684 0.47772 10.9195
433 5IRC GDP 0.000002069 0.47663 10.9453
434 1Z0K GTP 0.00000009054 0.62717 11.0465
435 4XOI GTP 0.000005054 0.51335 11.0619
436 5J1J ANP 0.00006102 0.48494 11.0619
437 1Z6T ADP 0.000399 0.45592 11.0619
438 3T12 GDP ALF 0.0000000111 0.66471 11.1111
439 3T1O GDP 0.0000000102 0.62951 11.1111
440 2A9K GDP 0.00000008513 0.61589 11.2299
441 2C9O ADP 0.0002025 0.47342 11.5044
442 3DOE GTP 0.00000002429 0.65266 11.5152
443 1LVG ADP 0.000002496 0.48938 11.6162
444 1Z0J GTP 0.0000001942 0.62019 11.8644
445 4DID GDP 0.0000002444 0.56586 11.9469
446 2QZ4 ADP 0.0000182 0.49822 11.9469
447 1X6V ADP 0.0002888 0.4799 11.9469
448 4BFW ZVW 0.001197 0.46485 11.9469
449 2ZEJ GDP 0.000003997 0.56068 11.9565
450 1UAD GNP 0.00000004769 0.64518 12
451 1ZC3 GNP 0.0000000969 0.63387 12
452 4ZI2 GNP 0.000004693 0.53686 12.0301
453 1Z06 GNP 0.0000001803 0.61653 12.1693
454 1KK8 BEF ADP 0.0008658 0.44125 12.2302
455 3DDC GNP 0.0000001914 0.62047 12.2699
456 2RCN GDP 0.0000000006244 0.64877 12.3894
457 4B47 GDP 0.000000007468 0.59756 12.3894
458 3RWO GDP 0.00000009208 0.6323 12.4324
459 1U8Z GDP 0.00000008388 0.62865 12.5
460 2J0V GDP 0.000000149 0.57384 12.7358
461 2VOH CIT 0.002656 0.46546 12.7389
462 2EFE GNH 0.00000007873 0.60667 12.8319
463 3EC1 GDP 0.000001481 0.53697 12.8319
464 2FAH GDP 0.0003986 0.45004 12.8319
465 4D81 ADP 0.00006276 0.43455 12.8319
466 2PL3 ADP 0.000342 0.42624 12.8319
467 3T5G GDP 0.0000001653 0.58375 13.2597
468 1NVV GNP 0.000000156 0.6245 13.2743
469 1NVU GTP 0.0000002158 0.61811 13.2743
470 4LC1 GDP 0.000001353 0.52888 13.2743
471 5WDR GNP 0.000002226 0.5359 13.4503
472 2XTN GTP 0.00001751 0.52513 13.7168
473 5SZH GNP 0.000001397 0.54404 13.7255
474 1Z83 AP5 0.00007962 0.51211 13.7755
475 1S9D GDP 0.0000000239 0.60465 13.7931
476 1NF3 GNP 0.00001834 0.49699 13.8462
477 2QN6 GDP 0.00000001115 0.59328 13.9785
478 1A4R GDP 0.0000008892 0.57454 14.1361
479 1A4R GNH 0.000001443 0.56233 14.1361
480 4ITR GDP 0.000001705 0.56214 14.1361
481 2NGR GDP 0.0000003511 0.55883 14.1361
482 1GRN GDP 0.000002463 0.55221 14.1361
483 2WMO GTP 0.0000001447 0.58681 14.2105
484 2W83 GTP 0.00000001949 0.65693 14.2857
485 3PQC GDP 0.000003017 0.53238 14.359
486 2IYL GDP 0.000003655 0.50786 14.4366
487 1KK1 GNP 0.00000000662 0.6002 14.6018
488 4H1V GNP 0.00000448 0.54089 14.6018
489 1S8F GDP 0.00000005966 0.64593 14.6893
490 3EWA ANP 0.00008045 0.45494 14.9068
491 4YC7 GNP 0.000004973 0.50211 14.9171
492 4LJ9 ACP 0.0009496 0.41577 15.0442
493 3TK1 GDP 0.0000003234 0.53082 15.4867
494 1R2Q GNP 0.000000435 0.61915 15.8824
495 5H56 TYD 0.0009617 0.43462 15.8974
496 5H56 ADP 0.0009617 0.43462 15.8974
497 1ZJ6 G3D 0.00000003194 0.59935 16.0428
498 3MJH GTP 0.0000001672 0.62061 16.0714
499 2HCJ GDP 0.00000002292 0.58148 16.2162
500 1RJ9 GCP 0.00006511 0.52866 16.3717
501 2C04 GCP 0.0000186 0.51394 16.3717
502 2GK6 ADP 0.0001202 0.4311 16.3717
503 5BXQ GDP 0.00000006908 0.51939 16.5354
504 1I4D GDP 0.00000009912 0.55766 16.9643
505 5HCN GCP 0.0000003655 0.63025 17.6991
506 1Z2A GDP 0.00000001897 0.58571 17.8571
507 3GJ4 GDP 0.00000005195 0.58199 18.1818
508 2HT6 GDP 0.000000002385 0.6157 18.3908
509 5E5U MLI 0.009344 0.42303 18.5841
510 5MVR ADP 0.00004093 0.42045 19.1358
511 2Y65 ADP 0.000008681 0.44722 19.469
512 5KDO GDP 0.000000197 0.60228 20.2703
513 4WZA ACP 0.0001542 0.5259 20.354
514 4WZA ADP 0.0001781 0.5228 20.354
515 1GOT GDP 0.00000007282 0.62846 20.5479
516 1NY5 ADP 0.0004802 0.45241 21.2389
517 3GJ7 GDP 0.00000008208 0.57698 21.4286
518 1HTW ADP 0.00002938 0.4821 22.1519
519 5L3R GCP 0.00002725 0.49471 23.0089
520 1GUA GNP 0.0000001276 0.62846 23.9521
521 4U5X GNP 0.0000001214 0.61246 24.7191
522 3E70 GDP 0.000004191 0.51645 26.9911
523 3KUD GDP 0.0000001028 0.6188 27.1605
524 3QF7 ANP 0.001571 0.43211 28
525 4DKX GDP 0.00000001378 0.60179 28.7611
526 2XAU ADP 0.002802 0.40705 28.7611
527 4C4P GNP 0.000000122 0.62933 28.972
528 5L3S GNP 0.00004982 0.47446 30.0885
529 5L3W GDP 0.00004552 0.43782 30.0885
530 2X77 GDP 0.00000006201 0.59164 32.8042
531 1GP2 GDP 0.00000008352 0.62873 33.8028
532 2Y8E GNP 0.0000001754 0.61968 35.7542
533 2FFQ GSP 0.000000244 0.6157 38.5965
534 1YZQ GNP 0.0000002407 0.61596 42.3529
Pocket No.: 2; Query (leader) PDB : 2HF9; Ligand: GSP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2hf9.bio2) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2HF9; Ligand: GSP; Similar sites found: 8
This union binding pocket(no: 3) in the query (biounit: 2hf9.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2PEZ GGZ 0.0002103 0.41981 1.11732
2 5X40 ACP 0.001177 0.41603 2.65487
3 5J1S ATP 0.0004749 0.4441 3.09735
4 5EP2 AZU 0.002298 0.4021 3.53982
5 3MBI HSX 0.02812 0.40166 3.9823
6 5M7P ADP 0.0001131 0.43898 4.86726
7 1G8S MET 0.02899 0.40663 6.19469
8 5HR5 ADP 0.0008116 0.40176 12.3894
Pocket No.: 4; Query (leader) PDB : 2HF9; Ligand: GSP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2hf9.bio1) has 26 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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