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Receptor
PDB id Resolution Class Description Source Keywords
2HW1 2.1 Å EC: 2.7.1.3 CRYSTAL STRUCTURE OF HUMAN KETOHEXOKINASE COMPLEXED TO DIFFE MOLECULES HOMO SAPIENS FRUCTOSE KINASE TRANSFERASE
Ref.: STRUCTURES OF ALTERNATIVELY SPLICED ISOFORMS OF HUM KETOHEXOKINASE. ACTA CRYSTALLOGR.,SECT.D V. 65 201 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:301;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
FRU A:601;
Valid;
none;
submit data
180.156 C6 H12 O6 C([C@...
GOL A:501;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
SO4 A:401;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2HW1 2.1 Å EC: 2.7.1.3 CRYSTAL STRUCTURE OF HUMAN KETOHEXOKINASE COMPLEXED TO DIFFE MOLECULES HOMO SAPIENS FRUCTOSE KINASE TRANSFERASE
Ref.: STRUCTURES OF ALTERNATIVELY SPLICED ISOFORMS OF HUM KETOHEXOKINASE. ACTA CRYSTALLOGR.,SECT.D V. 65 201 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2HW1 - FRU C6 H12 O6 C([C@@H]1[....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2HW1 - FRU C6 H12 O6 C([C@@H]1[....
2 3NBW - TR4 C11 H10 N4 S CSc1c(c(n(....
3 5WBM Kd = 20 uM A4G C13 H18 N4 O Cc1c[nH]c2....
4 5WBO Kd = 62 uM A1Y C12 H15 N3 O Cc1cc(nc(c....
5 5WBQ ic50 = 1.48 uM A3J C16 H17 F3 N4 O CCc1cc2c([....
6 3NBV - FRU C6 H12 O6 C([C@@H]1[....
7 5WBZ ic50 = 0.34 uM A4J C16 H19 F3 N4 O3 C[C@@]1(CC....
8 3NC2 - QUZ C8 H6 N2 c1ccc2c(c1....
9 3NC9 ic50 = 330 nM TR3 C20 H22 N4 O S CSc1c2ccc(....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2HW1 - FRU C6 H12 O6 C([C@@H]1[....
2 3NBW - TR4 C11 H10 N4 S CSc1c(c(n(....
3 5WBM Kd = 20 uM A4G C13 H18 N4 O Cc1c[nH]c2....
4 5WBO Kd = 62 uM A1Y C12 H15 N3 O Cc1cc(nc(c....
5 5WBQ ic50 = 1.48 uM A3J C16 H17 F3 N4 O CCc1cc2c([....
6 3NBV - FRU C6 H12 O6 C([C@@H]1[....
7 5WBZ ic50 = 0.34 uM A4J C16 H19 F3 N4 O3 C[C@@]1(CC....
8 3NC2 - QUZ C8 H6 N2 c1ccc2c(c1....
9 3NC9 ic50 = 330 nM TR3 C20 H22 N4 O S CSc1c2ccc(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 373
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 AP5 0.802632 0.945205
5 ADP 0.802632 0.972222
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 HEJ 0.772152 0.972222
9 ATP 0.772152 0.972222
10 AT4 0.769231 0.933333
11 AN2 0.769231 0.986111
12 5FA 0.7625 0.972222
13 AQP 0.7625 0.972222
14 M33 0.759494 0.932432
15 MAP 0.752941 0.972973
16 ACP 0.75 0.945946
17 AR6 0.740741 0.945205
18 APR 0.740741 0.945205
19 ACQ 0.73494 0.945946
20 AD9 0.731707 0.945946
21 SAP 0.731707 0.921053
22 AGS 0.731707 0.921053
23 A 0.723684 0.944444
24 AMP 0.723684 0.944444
25 ATF 0.717647 0.933333
26 ADX 0.716049 0.851852
27 CA0 0.716049 0.92
28 6YZ 0.709302 0.945946
29 50T 0.707317 0.932432
30 PRX 0.698795 0.87013
31 ABM 0.696203 0.893333
32 AP2 0.679012 0.933333
33 A12 0.679012 0.933333
34 APC 0.678571 0.933333
35 T99 0.674419 0.933333
36 TAT 0.674419 0.933333
37 A22 0.674157 0.958904
38 SRA 0.670886 0.894737
39 SRP 0.670455 0.883117
40 5AL 0.666667 0.906667
41 A1R 0.659341 0.884615
42 ADQ 0.659341 0.92
43 A3R 0.659341 0.884615
44 3OD 0.648936 0.92
45 BIS 0.648936 0.909091
46 5SV 0.648352 0.82716
47 9X8 0.645161 0.896104
48 OAD 0.645161 0.92
49 25L 0.642105 0.958904
50 AMO 0.641304 0.907895
51 G5P 0.636364 0.897436
52 DLL 0.634409 0.906667
53 AHX 0.634409 0.897436
54 00A 0.634409 0.860759
55 ADV 0.632184 0.907895
56 RBY 0.632184 0.907895
57 ADP PO3 0.632184 0.917808
58 NB8 0.631579 0.897436
59 25A 0.630435 0.945205
60 OOB 0.630435 0.906667
61 8QN 0.630435 0.906667
62 G3A 0.626263 0.897436
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 TXA 0.614583 0.907895
67 1ZZ 0.614583 0.819277
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 9ZD 0.612903 0.909091
71 9ZA 0.612903 0.909091
72 3UK 0.610526 0.894737
73 SON 0.604651 0.907895
74 ADP ALF 0.604396 0.848101
75 ALF ADP 0.604396 0.848101
76 PR8 0.604167 0.829268
77 B5V 0.604167 0.883117
78 WAQ 0.604167 0.860759
79 4UV 0.6 0.871795
80 GAP 0.6 0.87013
81 PTJ 0.597938 0.873418
82 FYA 0.597938 0.881579
83 VO4 ADP 0.597826 0.906667
84 ADP VO4 0.597826 0.906667
85 LMS 0.597561 0.829268
86 UP5 0.596154 0.896104
87 FA5 0.59596 0.883117
88 YAP 0.59596 0.871795
89 PAP 0.595506 0.958333
90 A4P 0.59434 0.823529
91 XAH 0.59 0.841463
92 4UU 0.588235 0.871795
93 AFH 0.588235 0.8625
94 9SN 0.585859 0.85
95 2A5 0.58427 0.894737
96 T5A 0.583333 0.821429
97 DQV 0.582524 0.932432
98 NAI 0.580952 0.884615
99 B5M 0.58 0.871795
100 B5Y 0.58 0.871795
101 ITT 0.579545 0.917808
102 ATR 0.577778 0.944444
103 OMR 0.575472 0.831325
104 5AS 0.574713 0.781609
105 YLP 0.571429 0.8
106 48N 0.571429 0.873418
107 AP0 0.570093 0.873418
108 4TC 0.570093 0.873418
109 7D3 0.569767 0.881579
110 ADJ 0.568807 0.831325
111 GNP 0.568421 0.922078
112 9GM 0.568421 0.922078
113 DAL AMP 0.568421 0.881579
114 6V0 0.566038 0.873418
115 TXD 0.566038 0.884615
116 DND 0.566038 0.907895
117 NAX 0.566038 0.851852
118 4UW 0.566038 0.839506
119 NXX 0.566038 0.907895
120 XYA 0.565789 0.821918
121 RAB 0.565789 0.821918
122 ADN 0.565789 0.821918
123 AOC 0.564706 0.8
124 7D4 0.561798 0.881579
125 ADP BMA 0.561224 0.894737
126 TXE 0.560748 0.884615
127 TYM 0.560748 0.883117
128 GA7 0.557692 0.883117
129 YLC 0.555556 0.819277
130 YLB 0.555556 0.8
131 139 0.554545 0.851852
132 5N5 0.551282 0.797297
133 JB6 0.55 0.860759
134 LAQ 0.54717 0.819277
135 F2R 0.544643 0.843373
136 MYR AMP 0.544554 0.797619
137 5CD 0.544304 0.783784
138 A4D 0.544304 0.797297
139 80F 0.54386 0.821429
140 7MD 0.542857 0.864198
141 6AD 0.542553 0.886076
142 A2R 0.541667 0.958904
143 UPA 0.541284 0.884615
144 YLA 0.540541 0.8
145 A A 0.54 0.918919
146 BTX 0.539823 0.821429
147 COD 0.539823 0.793103
148 HFD 0.537634 0.921053
149 G5A 0.537634 0.781609
150 3DH 0.535714 0.753247
151 AYB 0.535714 0.790698
152 CNA 0.535714 0.907895
153 BT5 0.535088 0.811765
154 ATP A A A 0.533981 0.905405
155 IOT 0.531532 0.811765
156 MTA 0.53012 0.753247
157 3AM 0.529412 0.90411
158 A3P 0.52809 0.944444
159 PPS 0.526316 0.851852
160 NAD 0.526316 0.906667
161 EP4 0.52439 0.734177
162 7D5 0.52381 0.855263
163 AMP DBH 0.52381 0.87013
164 J7C 0.522727 0.75
165 A5A 0.520833 0.809524
166 EAD 0.520661 0.851852
167 TSB 0.520408 0.821429
168 AHZ 0.518519 0.797619
169 DTA 0.518072 0.766234
170 M2T 0.518072 0.716049
171 A3D 0.517241 0.894737
172 6RE 0.517241 0.740741
173 YLY 0.516949 0.790698
174 SSA 0.515464 0.802326
175 NA7 0.514852 0.933333
176 ARG AMP 0.514019 0.809524
177 AR6 AR6 0.514019 0.893333
178 7MC 0.513514 0.843373
179 A2P 0.511111 0.930556
180 52H 0.510204 0.781609
181 VMS 0.510204 0.790698
182 54H 0.510204 0.790698
183 TYR AMP 0.509434 0.848101
184 TAD 0.509259 0.8625
185 NAQ 0.508333 0.85
186 A3N 0.505618 0.766234
187 AV2 0.505155 0.893333
188 53H 0.50505 0.781609
189 5CA 0.50505 0.802326
190 8X1 0.50505 0.755556
191 ARU 0.504951 0.839506
192 ZID 0.504132 0.894737
193 P1H 0.504 0.831325
194 NAE 0.5 0.871795
195 3AT 0.5 0.945205
196 AVV 0.5 0.873418
197 P5A 0.495146 0.747253
198 NSS 0.49505 0.802326
199 LSS 0.49505 0.764045
200 DSZ 0.49505 0.802326
201 N0B 0.491803 0.8
202 AF3 ADP 3PG 0.491071 0.817073
203 NVA LMS 0.490196 0.755556
204 DAT 0.489362 0.881579
205 IMO 0.488889 0.90411
206 ZAS 0.488636 0.792208
207 FDA 0.488372 0.813953
208 NAJ PZO 0.487395 0.85
209 4TA 0.487179 0.788235
210 LPA AMP 0.486486 0.797619
211 LEU LMS 0.485437 0.755556
212 DTP 0.484536 0.881579
213 V3L 0.484536 0.945205
214 S4M 0.483516 0.651685
215 GJV 0.483516 0.731707
216 DZD 0.483051 0.8625
217 2AM 0.482759 0.917808
218 5AD 0.481013 0.726027
219 GSU 0.480769 0.781609
220 KAA 0.480769 0.755556
221 NDE 0.480315 0.907895
222 M24 0.479339 0.851852
223 MAO 0.478261 0.761905
224 NEC 0.477778 0.727273
225 DSH 0.477778 0.707317
226 FAS 0.477273 0.831325
227 FAD 0.477273 0.831325
228 RGT 0.476636 0.933333
229 9K8 0.47619 0.698925
230 G A A A 0.474576 0.85
231 0WD 0.474576 0.897436
232 FNK 0.474074 0.786517
233 5X8 0.473684 0.74359
234 6FA 0.473282 0.821429
235 NDC 0.472868 0.85
236 FB0 0.472868 0.786517
237 YSA 0.472222 0.781609
238 7DD 0.468085 0.958333
239 OVE 0.466667 0.881579
240 MHZ 0.463158 0.701149
241 8PZ 0.462963 0.802326
242 A G 0.462185 0.860759
243 AMP NAD 0.462185 0.881579
244 A3G 0.461538 0.779221
245 NAJ PYZ 0.459677 0.809524
246 6C6 0.459184 0.858974
247 SFG 0.458333 0.730769
248 U A G G 0.458333 0.860759
249 7D7 0.45679 0.723684
250 128 0.45614 0.8
251 SFD 0.455224 0.736842
252 6IA 0.454545 0.817073
253 DDS 0.454545 0.855263
254 GDP 0.454545 0.896104
255 ODP 0.453782 0.886076
256 NJP 0.453782 0.921053
257 7DT 0.453608 0.958333
258 A7D 0.452632 0.75641
259 Z5A 0.452381 0.802326
260 WSA 0.452174 0.790698
261 U A 0.45082 0.884615
262 7C5 0.45045 0.797468
263 FAY 0.449275 0.841463
264 NDP 0.449153 0.897436
265 SA8 0.44898 0.690476
266 A5D 0.44898 0.766234
267 71V 0.446809 0.884615
268 GGZ 0.446602 0.804878
269 RFL 0.446043 0.802326
270 2SA 0.445545 0.907895
271 SAI 0.444444 0.716049
272 GP3 0.444444 0.897436
273 SAH 0.444444 0.725
274 PO4 PO4 A A A A PO4 0.443396 0.878378
275 A A A 0.443396 0.881579
276 4YB 0.442478 0.764045
277 SMM 0.441176 0.670455
278 S7M 0.441176 0.674419
279 GTP 0.441176 0.896104
280 Y3J 0.440476 0.706667
281 SAM 0.44 0.674419
282 649 0.439655 0.747253
283 12D 0.438596 0.809524
284 A3S 0.4375 0.789474
285 NPW 0.436975 0.864198
286 GCP 0.436893 0.873418
287 AAT 0.435644 0.690476
288 GNH 0.435644 0.909091
289 EEM 0.435644 0.674419
290 ETB 0.435484 0.813953
291 DCA 0.435484 0.804598
292 N6P 0.433962 0.890411
293 NZQ 0.433333 0.886076
294 TXP 0.433333 0.897436
295 PGS 0.43299 0.860759
296 APU 0.432203 0.871795
297 PUA 0.432 0.8625
298 62F 0.431655 0.841463
299 F2N 0.431507 0.795455
300 DA 0.430108 0.855263
301 D5M 0.430108 0.855263
302 J7V 0.429688 0.813953
303 NIA 0.428571 0.848101
304 COA 0.428571 0.804598
305 6K6 0.428571 0.905405
306 A3T 0.428571 0.8
307 0T1 0.428571 0.804598
308 P5F 0.427586 0.804598
309 AAM 0.425532 0.944444
310 0UM 0.424528 0.682353
311 8Q2 0.423729 0.775281
312 G1R 0.423077 0.884615
313 AMZ 0.422222 0.891892
314 C2R 0.422222 0.88
315 A U 0.420168 0.848101
316 IDP 0.42 0.894737
317 GSP 0.419048 0.851852
318 30N 0.418605 0.736842
319 CAO 0.418605 0.777778
320 DG1 0.418605 0.897436
321 1DG 0.418605 0.897436
322 COS 0.418605 0.786517
323 AMX 0.418605 0.813953
324 TM1 0.418182 0.797619
325 A6D 0.416667 0.746988
326 K15 0.416667 0.666667
327 V1N 0.415929 0.893333
328 CMX 0.415385 0.804598
329 SCO 0.415385 0.804598
330 GEK 0.415094 0.719512
331 XNP 0.414634 0.851852
332 NHD 0.414634 0.881579
333 9JJ 0.413793 0.841463
334 AIR 0.413793 0.876712
335 COK 0.413534 0.786517
336 G2R 0.412844 0.8625
337 ACO 0.412214 0.777778
338 FAM 0.412214 0.786517
339 FCX 0.412214 0.777778
340 NAP 0.410853 0.92
341 FA9 0.409396 0.843373
342 SXZ 0.409091 0.694118
343 HAX 0.409091 0.806818
344 TAP 0.407692 0.884615
345 2MC 0.407407 0.752688
346 62X 0.407407 0.651685
347 GKE 0.40708 0.8625
348 GDC 0.40708 0.8625
349 GDD 0.40708 0.8625
350 3KK 0.406015 0.786517
351 FYN 0.406015 0.804598
352 NVA 2AD 0.405941 0.740741
353 NA0 0.40458 0.907895
354 101 0.404255 0.855263
355 G 0.40404 0.883117
356 5GP 0.40404 0.883117
357 HDV 0.403846 0.87013
358 MGP 0.403846 0.8625
359 OXK 0.402985 0.786517
360 MCD 0.402985 0.786517
361 CA6 0.402985 0.714286
362 SOP 0.402985 0.786517
363 3AD 0.402299 0.783784
364 S8M 0.401869 0.78481
365 YE1 0.40146 0.795455
366 NMX 0.4 0.782609
367 7RP 0.4 0.902778
368 2VA 0.4 0.779221
369 1VU 0.4 0.777778
370 CO6 0.4 0.786517
371 CMC 0.4 0.786517
372 6G0 0.4 0.8625
373 GMV 0.4 0.873418
Ligand no: 2; Ligand: FRU; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 FRU 1 1
2 SF6 1 1
3 LFR 1 1
4 PSV 1 1
5 SF9 1 1
6 F6P 0.564103 0.744186
7 TA6 0.564103 0.744186
8 FRU FRU 0.511111 0.888889
9 LBS 0.511111 0.888889
10 F1X 0.487805 0.744186
11 LRH 0.484848 0.882353
12 0UB 0.479167 0.888889
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2HW1; Ligand: ANP; Similar sites found with APoc: 110
This union binding pocket(no: 1) in the query (biounit: 2hw1.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
1 1UO4 PIH None
2 6BOC RIM None
3 6BKL EU7 None
4 6BKK 308 None
5 4F4S EFO None
6 1JAY F42 1.41509
7 2V7B BEZ 1.67785
8 2PHF MAN MAN BMA MAN 1.98413
9 2PHT MAN MAN MAN BMA MAN 1.98413
10 2AUY NAG MAN MMA 1.98413
11 5JDA AMP 2.01342
12 1J2Z SOG 2.22222
13 4WBD CIT 2.34899
14 2OG7 AHB 2.34899
15 1SW0 PGA 2.41935
16 1Q7E MET 2.68456
17 4XH0 ADP 2.68456
18 4N4J HG1 2.68456
19 1BZL GCG 2.68456
20 4MGA 27L 2.7451
21 4MG9 27K 2.7451
22 2O66 FLC 2.96296
23 4OVZ P85 3.02013
24 4OW0 S88 3.02013
25 1Q19 SSC 3.02013
26 5CQG 55C 3.02013
27 4JWK CTN 3.10881
28 3ZS7 ATP 3.3557
29 2X0K PPV 3.3557
30 2NGR AF3 3.66492
31 4EN4 GT0 3.69128
32 4EN4 ATP 3.69128
33 4EN4 GT1 3.69128
34 1GPM CIT 3.69128
35 6CAM BGC 3.69128
36 3UDG TMP 3.69128
37 4Z7X 3CX 3.78151
38 2F6U CIT 3.84615
39 1KNM LAT 3.84615
40 1JJV ATP 3.8835
41 6BVK EAV 4.02685
42 6BVI EC4 4.02685
43 3RS8 APR 4.02685
44 5OD2 5ID 4.36242
45 3DRW AMP 4.36242
46 5VEQ PMP 4.36242
47 3K7S R52 4.46927
48 5LWY OLB 4.6729
49 5FPE 3TR 4.69799
50 1XPJ TLA 4.7619
51 5O0J 8BR 5.03356
52 1UA4 AMP 5.03356
53 2HIM ASN 5.03356
54 5MIT NAP 5.03356
55 5MIT FAD 5.03356
56 5L3S G 5.06757
57 5NBW 8SK 5.40541
58 1YP1 LYS ASN LEU 5.44554
59 4XF6 INS 5.49451
60 4XF6 LIP 5.49451
61 4XF6 ADP 5.49451
62 4DDY DN6 5.70342
63 3OTX AP5 5.7047
64 1YKJ PHB 5.7047
65 1YKJ FAD 5.7047
66 3LE7 ADE 5.74713
67 4C5N ACP 5.7971
68 4C5N PXL 5.7971
69 1FL2 FAD 5.80645
70 2J5V PCA 6.37584
71 2OUA AES 6.38298
72 1SBR VIB 6.5
73 4XDA RIB 6.71141
74 4XDA ADP 6.71141
75 1IZC PYR 6.71141
76 3CTY FAD 6.71141
77 5NM7 GLY 6.76692
78 5E5U MLI 6.81818
79 5TCI MLI 6.88406
80 2VOH CIT 7.00637
81 6C0B MLI 7.05128
82 3TAO PGH 7.11611
83 1LYX PGA 7.66129
84 4NPT 017 8.08081
85 3BOS CDP 8.26446
86 5YW5 ADE 8.37989
87 4PVV HO4 8.72483
88 2ABS ACP 8.72483
89 4BJH DOR 8.72483
90 2ZRU FMN 9.0604
91 2JGV ADP 9.39597
92 2JG1 ANP 9.39597
93 2VAR AMP 10.0671
94 2VAR ANP 10.0671
95 3HP9 CF1 10.0671
96 5C1M OLC 10.4
97 1JXN MFU 11.5702
98 4Y9J UCC 12.4161
99 3CQD ATP 13.7584
100 4RUS NAG 13.8655
101 4RUS NDG 13.8655
102 4ZGR NGA GAL 14.17
103 5ODQ 9SB 15.4639
104 5ODQ FAD 15.4639
105 3LOO B4P 18.4564
106 1XZ3 ICF 22.9885
107 1V1A ADP 36.9128
108 1RKD RIB 37.8641
109 1RKD ADP 37.8641
110 2C49 ANP 40.2685
Pocket No.: 2; Query (leader) PDB : 2HW1; Ligand: ANP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2hw1.bio1) has 23 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2HW1; Ligand: FRU; Similar sites found with APoc: 137
This union binding pocket(no: 3) in the query (biounit: 2hw1.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 1I7L ATP 0.671141
2 6CMJ F6J 1.00671
3 5LLT DND 1.40845
4 2BNF UTP 1.65975
5 1H74 ILE 1.68919
6 1NZY BCA 1.85874
7 4C3Y ANB 2.01342
8 2ZB4 5OP 2.01342
9 2ZB4 NAP 2.01342
10 1DFO PLG 2.01342
11 2ZB3 NDP 2.01342
12 4WXG 2BO 2.01342
13 1GUZ NAD 2.01342
14 4HKP TKW 2.01342
15 4HKP 16B 2.01342
16 2XBN PMP 2.34899
17 6CQF F97 2.3569
18 1Z6K OAA 2.38908
19 5YSQ INS 2.44755
20 3R5W F42 2.67857
21 4GN8 ASO 2.68456
22 1PK8 ATP 2.68456
23 5GUD NDP 2.68456
24 5GUD 2IT 2.68456
25 1JIL 485 2.68456
26 6C8R SAH 2.68456
27 1EU1 GLC 3.02013
28 4OR7 NAP 3.0303
29 3ZG6 APR 3.04054
30 2QTR NXX 3.1746
31 3NUG NAD 3.23887
32 1S8G DAO 3.30579
33 1B8U OAA 3.3557
34 2CVQ NDP 3.3557
35 1ELU PDA 3.3557
36 5W19 9TD 3.3557
37 2ZA5 2FF 3.67347
38 1UJP CIT 3.69004
39 2H29 DND 3.7037
40 2OKL BB2 3.78378
41 1H0H MGD 4.02685
42 4MO4 ACP 4.02685
43 2YYY NAP 4.02685
44 3MKH FAD 4.02685
45 3MJY IJZ 4.02685
46 3MJY FMN 4.02685
47 1EZ4 NAD 4.02685
48 2A8Y MTA 4.07407
49 3C2O NTM 4.08163
50 5A1T OXM 4.10557
51 5A1T NAI 4.10557
52 2GQR ADP 4.21941
53 2GQS ADP 4.21941
54 5OD2 GLC 4.36242
55 5ZCT ANP 4.36242
56 2XIQ MLC 4.36242
57 3UG4 AHR 4.36242
58 1QIN GIP 4.37158
59 1KRR ACO 4.4335
60 1O6Z NAD 4.69799
61 1UA4 GLC 5.03356
62 1UA4 BGC 5.03356
63 5O0J GLC 5.03356
64 5DK4 ATP 5.03356
65 5DK4 5BX 5.03356
66 5Y8L NAD 5.08475
67 5Y8L HUI 5.08475
68 4B7X NAP 5.36913
69 5O5Y GLC 5.38793
70 1ERB ETR 5.46448
71 4XF6 LIP 5.49451
72 4XF6 INS 5.49451
73 4XF6 ADP 5.49451
74 4O9S 2RY 5.5814
75 3OTX AP5 5.7047
76 5AWQ GLC GLC 5.7047
77 4CZG QH3 5.7047
78 4CZG ADP 5.7047
79 2TPS TPS 5.72687
80 1ONI BEZ 5.7971
81 2I6A 5I5 6.04027
82 1W4R TTP 6.15385
83 5XQW 8EU 6.16114
84 4LRZ ADP 6.16114
85 4BTI 7R9 6.25
86 3B1Q NOS 6.37584
87 4BA5 PXG 6.37584
88 6CD1 PLG 6.37584
89 6CD1 PLS 6.37584
90 1ON3 MCA 6.37584
91 4XDA ADP 6.71141
92 4XDA RIB 6.71141
93 5TPR NAD 6.71141
94 3FV3 IVA VAL VAL STA ALA STA 7.04698
95 5NUE NAD 7.04698
96 5NUF NAD 7.04698
97 5GVL PLG 7.38255
98 5GVL GI8 7.38255
99 4W6Z 8ID 7.38255
100 1I8T FAD 7.71812
101 2J5B TYE 7.71812
102 1DJ9 KAM 7.71812
103 2TPL HPP 7.71812
104 2Z6J FMN 7.71812
105 1G27 BB1 7.7381
106 5JE8 NAD 8.05369
107 2XZ9 PYR 8.05369
108 4ZSY RW2 8.38926
109 4PVV HO4 8.72483
110 2ABS ACP 8.72483
111 5MDH NAD 8.72483
112 2Q2Y MKR 8.72483
113 4MDH NAD 8.72483
114 3C3N FMN 8.72483
115 4C2V YJA 9.12281
116 2JG1 TA6 9.39597
117 4ZV1 ARG 9.44206
118 2P3V SRT 9.76562
119 2VAR KDG 10.0671
120 2VAR KDF 10.0671
121 2HZY DHJ 10.0671
122 4HXY NDP 11.0738
123 2CM4 RCL 12
124 4K3H 1OM 12.7119
125 1T0S BML 12.7907
126 5N5U AMP 13.4228
127 3CQD ATP 13.7584
128 5O2Z FLC 14.2857
129 1MFA GLA MMA ABE 15.748
130 4R38 RBF 17.1429
131 3LOO B4P 18.4564
132 5L0S UDP 19.0476
133 4I3V NAD 36.5772
134 1V1A KDG 36.9128
135 1RKD RIB 37.8641
136 1RKD ADP 37.8641
137 2C49 ADN 40.2685
Pocket No.: 4; Query (leader) PDB : 2HW1; Ligand: FRU; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2hw1.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
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