Receptor
PDB id Resolution Class Description Source Keywords
2IMG 1.93 Å EC: 3.1.3.16 CRYSTAL STRUCTURE OF DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 FROM HOMO SAPIENS IN COMPLEX WITH LIGAND MALATE ION HOMO SAPIENS DUSP23 VHZ LDP-3 DUAL SPECICITY PROTEIN PHOSPHATASE 23 DUS23_HUMAN MALATE 8673A STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS NYSGXRC HYDROLASE
Ref.: STRUCTURE OF HUMAN DUAL SPECIFICITY PROTEIN PHOSPHATASE 23, VHZ, ENZYME-SUBSTRATE/PRODUCT COMPLEX. J.BIOL.CHEM. V. 283 8946 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
MLT A:501;
Valid;
none;
submit data
134.087 C4 H6 O5 C([C@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2IMG 1.93 Å EC: 3.1.3.16 CRYSTAL STRUCTURE OF DUAL SPECIFICITY PROTEIN PHOSPHATASE 23 FROM HOMO SAPIENS IN COMPLEX WITH LIGAND MALATE ION HOMO SAPIENS DUSP23 VHZ LDP-3 DUAL SPECICITY PROTEIN PHOSPHATASE 23 DUS23_HUMAN MALATE 8673A STRUCTURAL GENOMICS PSI PROTEIN STRUCTURE INITIATIVE NEW YORK SGX RESEARCH CENTER FOR STRUCTURAL GENOMICS NYSGXRC HYDROLASE
Ref.: STRUCTURE OF HUMAN DUAL SPECIFICITY PROTEIN PHOSPHATASE 23, VHZ, ENZYME-SUBSTRATE/PRODUCT COMPLEX. J.BIOL.CHEM. V. 283 8946 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 22 families.
1 2IMG - MLT C4 H6 O5 C([C@H](C(....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 17 families.
1 2IMG - MLT C4 H6 O5 C([C@H](C(....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 13 families.
1 2IMG - MLT C4 H6 O5 C([C@H](C(....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: MLT; Similar ligands found: 13
No: Ligand ECFP6 Tc MDL keys Tc
1 DMR 1 1
2 MLT 1 1
3 LMR 1 1
4 DGY 0.52381 0.818182
5 3HG 0.52381 0.761905
6 3HL 0.5 0.666667
7 3HR 0.5 0.666667
8 TRC 0.478261 0.666667
9 S2G 0.461538 0.809524
10 2HG 0.461538 0.809524
11 JYD 0.458333 0.761905
12 2RH 0.458333 0.652174
13 ICT 0.444444 0.904762
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2IMG; Ligand: MLT; Similar sites found with APoc: 1
This union binding pocket(no: 1) in the query (biounit: 2img.bio1) has 11 residues
No: Leader PDB Ligand Sequence Similarity
1 2CNE DFJ 28.4768
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