Receptor
PDB id Resolution Class Description Source Keywords
2IOY 1.9 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THERMOANAEROBACTER TENGCONGENSIS RIBOSE PROTEIN THERMOANAEROBACTER TENGCONGENSIS RIBOSE BINDING PROTEIN SUGAR BINDING PROTEIN THERMOPHILIC
Ref.: THE BACKBONE STRUCTURE OF THE THERMOPHILIC THERMOANAEROBACTER TENGCONGENSIS RIBOSE BINDING PRO ESSENTIALLY IDENTICAL TO ITS MESOPHILIC E. COLI HOM BMC STRUCT.BIOL. V. 8 20 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
RIP A:401;
B:402;
Valid;
Valid;
none;
none;
submit data
150.13 C5 H10 O5 C1[C@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2IOY 1.9 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THERMOANAEROBACTER TENGCONGENSIS RIBOSE PROTEIN THERMOANAEROBACTER TENGCONGENSIS RIBOSE BINDING PROTEIN SUGAR BINDING PROTEIN THERMOPHILIC
Ref.: THE BACKBONE STRUCTURE OF THE THERMOPHILIC THERMOANAEROBACTER TENGCONGENSIS RIBOSE BINDING PRO ESSENTIALLY IDENTICAL TO ITS MESOPHILIC E. COLI HOM BMC STRUCT.BIOL. V. 8 20 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 2IOY - RIP C5 H10 O5 C1[C@H]([C....
70% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 175 families.
1 1DBP - RIP C5 H10 O5 C1[C@H]([C....
2 2DRI Kd = 0.13 uM RIP C5 H10 O5 C1[C@H]([C....
3 1DRK Kd = 0.15 uM RIP C5 H10 O5 C1[C@H]([C....
4 1DRJ Kd = 0.04 uM RIP C5 H10 O5 C1[C@H]([C....
5 2IOY - RIP C5 H10 O5 C1[C@H]([C....
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 174 families.
1 2FN8 - RIP C5 H10 O5 C1[C@H]([C....
2 1RPJ Kd = 0.33 uM ALL C6 H12 O6 C([C@@H]1[....
3 2DRI Kd = 0.13 uM RIP C5 H10 O5 C1[C@H]([C....
4 1DRK Kd = 0.15 uM RIP C5 H10 O5 C1[C@H]([C....
5 1DRJ Kd = 0.04 uM RIP C5 H10 O5 C1[C@H]([C....
6 2IOY - RIP C5 H10 O5 C1[C@H]([C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: RIP; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 RIP 1 1
2 XYS 1 1
3 ARB 1 1
4 HSY 1 1
5 ARA 1 1
6 XYP 1 1
7 LXC 1 1
8 0MK 1 1
9 XYP XYS 0.414634 0.84375
10 BXP 0.414634 0.84375
11 XYS XYP 0.414634 0.84375
12 FU4 0.4 0.896552
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2IOY; Ligand: RIP; Similar sites found with APoc: 1
This union binding pocket(no: 1) in the query (biounit: 2ioy.bio1) has 12 residues
No: Leader PDB Ligand Sequence Similarity
1 4IRX INS 48.0565
Pocket No.: 2; Query (leader) PDB : 2IOY; Ligand: RIP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2ioy.bio2) has 12 residues
No: Leader PDB Ligand Sequence Similarity
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