Receptor
PDB id Resolution Class Description Source Keywords
2J59 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE ARF1:ARHGAP21-ARFBD COMPLEX MUS MUSCULUS ARF ARF1 ARFBD ARHGAP21 MYRISTATE TRANSPORT NUCLEOTIDE-BINDING RHOGAP PROTEIN HYDROLASE PROTEIN TRANSPORT ACTIN ORGANIZATION SMALL GTP-BINDING PROTEIN GOLGI APPARATUS
Ref.: STRUCTURAL BASIS FOR ARF1-MEDIATED RECRUITMENT OF ARHGAP21 TO GOLGI MEMBRANES. EMBO J. V. 26 1953 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DIO A:1183;
B:1183;
F:1183;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
88.105 C4 H8 O2 C1COC...
EDO C:1183;
E:1183;
O:2063;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
GTP A:1181;
B:1181;
C:1181;
D:1181;
E:1181;
F:1181;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
submit data
523.18 C10 H16 N5 O14 P3 c1nc2...
MG A:1182;
B:1182;
C:1182;
D:1182;
E:1182;
F:1182;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
SO4 M:2064;
N:2064;
O:2062;
P:2064;
Q:2064;
R:2064;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2J59 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF THE ARF1:ARHGAP21-ARFBD COMPLEX MUS MUSCULUS ARF ARF1 ARFBD ARHGAP21 MYRISTATE TRANSPORT NUCLEOTIDE-BINDING RHOGAP PROTEIN HYDROLASE PROTEIN TRANSPORT ACTIN ORGANIZATION SMALL GTP-BINDING PROTEIN GOLGI APPARATUS
Ref.: STRUCTURAL BASIS FOR ARF1-MEDIATED RECRUITMENT OF ARHGAP21 TO GOLGI MEMBRANES. EMBO J. V. 26 1953 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 2J59 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 2J59 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 2J59 - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GTP; Similar ligands found: 147
No: Ligand ECFP6 Tc MDL keys Tc
1 GTP 1 1
2 GP3 0.921053 0.973684
3 GDP 0.909091 1
4 GSP 0.853659 0.948718
5 GNH 0.82716 0.986667
6 G1R 0.819277 0.986667
7 GAV 0.811765 0.961039
8 GNP 0.809524 0.973684
9 GCP 0.797619 0.973684
10 5GP 0.797468 0.986486
11 G 0.797468 0.986486
12 GMV 0.764706 0.973684
13 G2R 0.764045 0.961039
14 G5P 0.755319 0.973684
15 GTG 0.752688 0.936709
16 G2P 0.747126 0.961039
17 G3A 0.744681 0.973684
18 GDD 0.741935 0.961039
19 GKE 0.741935 0.961039
20 GDC 0.741935 0.961039
21 0O2 0.736264 0.986486
22 GP2 0.729412 0.961039
23 6CK 0.726316 0.936709
24 Y9Z 0.723404 0.902439
25 GPG 0.717391 0.961039
26 GFB 0.715789 0.961039
27 GDR 0.715789 0.961039
28 GDP MG 0.712644 0.923077
29 GDP BEF 0.704545 0.9
30 GPD 0.704082 0.925
31 JB2 0.693878 0.961039
32 GKD 0.693878 0.961039
33 GCP G 0.692308 0.935065
34 GDX 0.686869 0.973684
35 ALF 5GP 0.685393 0.888889
36 GTP MG 0.681319 0.923077
37 BEF GDP 0.681319 0.888889
38 GH3 0.681319 0.973333
39 YGP 0.677083 0.901235
40 G3D 0.67033 0.986486
41 GDP AF3 0.659574 0.888889
42 GDP ALF 0.659574 0.888889
43 DGT 0.659341 0.923077
44 GMP 0.658228 0.88
45 G4P 0.655914 0.986486
46 JB3 0.653846 0.948718
47 NGD 0.647619 0.961039
48 CAG 0.642202 0.880952
49 2MD 0.62963 0.891566
50 G G 0.622449 0.935065
51 MGP 0.619565 0.961039
52 U2G 0.616822 0.936709
53 6G0 0.612903 0.961039
54 MGD 0.612613 0.891566
55 TPG 0.608696 0.840909
56 CG2 0.605505 0.936709
57 GDP 7MG 0.601942 0.911392
58 FEG 0.601852 0.879518
59 ZGP 0.59633 0.869048
60 MD1 0.591304 0.891566
61 PGD 0.591304 0.925
62 3GP 0.590909 0.946667
63 GPX 0.581633 0.946667
64 DGI 0.580645 0.923077
65 IDP 0.576087 0.972973
66 DBG 0.567797 0.948718
67 FE9 0.555556 0.776596
68 2GP 0.555556 0.96
69 G4M 0.547619 0.880952
70 BGO 0.544643 0.924051
71 I2C FE2 CMO CMO 0.538462 0.808989
72 ATP 0.537634 0.92
73 G1G 0.533898 0.925
74 AQP 0.531915 0.92
75 5FA 0.531915 0.92
76 G A A A 0.525862 0.923077
77 U A G G 0.521368 0.935065
78 01G 0.518868 0.902439
79 ITT 0.510638 0.868421
80 P2G 0.510638 0.883117
81 GGM 0.504274 0.901235
82 G1R G1R 0.504065 0.924051
83 DGP 0.5 0.910256
84 PGD O 0.5 0.850575
85 MGO 0.5 0.864198
86 P1G 0.5 0.871795
87 DG 0.5 0.910256
88 GTA 0.495495 0.936709
89 B4P 0.489362 0.894737
90 AP5 0.489362 0.894737
91 IMP 0.489362 0.959459
92 7DT 0.484536 0.906667
93 G G U 0.482143 0.935065
94 GPC 0.479339 0.879518
95 G C 0.478992 0.9
96 BA3 0.478723 0.894737
97 ADP 0.473684 0.92
98 G2Q 0.471698 0.961039
99 G7M 0.46875 0.948052
100 25L 0.458716 0.907895
101 A2D 0.457447 0.894737
102 RGT 0.45045 0.909091
103 AGS 0.45 0.873418
104 SAP 0.45 0.873418
105 SGP 0.44898 0.82716
106 U G A 0.448529 0.888889
107 A4P 0.445378 0.869048
108 G G G RPC 0.442623 0.875
109 ACQ 0.441176 0.896104
110 ANP 0.441176 0.896104
111 8GT 0.441176 0.875
112 APC G U 0.44 0.886076
113 G U34 0.438017 0.888889
114 6AD 0.436893 0.841463
115 G G G C 0.433071 0.9125
116 UP5 0.432203 0.873418
117 35G 0.431373 0.933333
118 C2E 0.431373 0.921053
119 PCG 0.431373 0.933333
120 A G C C 0.429688 0.911392
121 5GP 5GP 0.427184 0.883117
122 TAT 0.427184 0.884615
123 APR 0.425743 0.894737
124 AR6 0.425743 0.894737
125 AN2 0.424242 0.907895
126 7DD 0.424242 0.906667
127 DG DG 0.423423 0.865854
128 AD9 0.421569 0.896104
129 M33 0.42 0.883117
130 7D4 0.42 0.835443
131 UCG 0.419847 0.911392
132 H6Y 0.419048 0.946667
133 G C C C 0.416667 0.924051
134 ACP 0.415842 0.896104
135 T5A 0.414634 0.802326
136 MGQ 0.412844 0.935897
137 ADQ 0.412844 0.871795
138 A1R 0.412844 0.839506
139 MGT 0.411215 0.823529
140 A G U 0.410072 0.888889
141 93A 0.41 0.833333
142 A22 0.407407 0.907895
143 CA0 0.405941 0.896104
144 ATF 0.40566 0.884615
145 AGO 0.404762 0.888889
146 MGV 0.401786 0.890244
147 CGP 0.4 0.86747
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2J59; Ligand: GTP; Similar sites found: 435
This union binding pocket(no: 1) in the query (biounit: 2j59.bio1) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2W58 ADP 0.000001538 0.41038 None
2 1PTR PRB 0.02978 0.40437 None
3 1DAK DPU 0.0001954 0.48628 1.80723
4 3BOS CDP 0.0001165 0.41168 1.80723
5 1YZQ GNP 0.00000000002124 0.75672 2.38095
6 2FFQ GSP 0.00000000002568 0.75328 2.38095
7 1UJ2 C5P 0.0001427 0.47148 2.97619
8 1UJ2 ADP 0.0004085 0.4524 2.97619
9 4WZ6 ATP 0.00001084 0.58678 3.01205
10 3Q72 GNP 0.0000000002918 0.58255 3.01205
11 2J0V GDP 0.00000009648 0.53378 3.01205
12 4NCN GTP 0.00000000002287 0.7449 3.61446
13 2DPY ADP 0.0005319 0.4919 3.61446
14 1NJF AGS 0.0006405 0.43359 3.61446
15 1NJF ADP 0.0003801 0.43058 3.61446
16 2RGX AP5 0.0004004 0.47251 4.16667
17 1UKZ ADP 0.001668 0.43564 4.16667
18 5E5U MLI 0.01623 0.41422 4.16667
19 2BVN GNP 0.00000000002475 0.79819 4.21687
20 1D8T GDP 0.0000000002539 0.5985 4.21687
21 3H86 AP5 0.001104 0.44467 4.21687
22 1F2U ATP 0.001252 0.43207 4.72973
23 1V8K ANP 0.000001628 0.47845 4.7619
24 3DZD ADP 0.0007647 0.40975 4.7619
25 2HCJ GDP 0.00000000008981 0.59804 4.77612
26 4LPS GDP 0.00000004034 0.67079 4.81928
27 4ZG4 VO4 ADP 0.0000003373 0.57357 4.81928
28 1IWE IMP 0.0002581 0.51842 4.81928
29 2FAH GDP 0.0003788 0.42466 4.81928
30 3FYH ADP 0.001948 0.42072 4.81928
31 2GDJ ANP 0.0002318 0.40677 4.81928
32 4FCW ADP 0.0004504 0.40822 5.14469
33 4PX9 ADP 0.0003567 0.49424 5.35714
34 1KO8 6PG 0.0004295 0.42809 5.35714
35 5WRI A3P 0.004806 0.40595 5.35714
36 5WRJ A3P 0.00444 0.4059 5.35714
37 2C78 GNP 0.000000000004857 0.78311 5.42169
38 2C77 GNP 0.000000000001252 0.76876 5.42169
39 3KTA AP5 0.0005297 0.46378 5.42169
40 1YTM ATP 0.000379 0.45646 5.42169
41 3VX3 ADP 0.0002023 0.44188 5.42169
42 5KSP GDP 0.0000001594 0.64229 5.78947
43 4IOK ADP 0.0002438 0.46353 5.95238
44 4IOK XPO 0.0001832 0.46317 5.95238
45 1GOJ ADP 0.0000003536 0.67668 6.0241
46 1JJ7 ADP 0.0000006596 0.67057 6.0241
47 2XTN GTP 0.00001031 0.51253 6.0241
48 3QXC ATP 0.0003137 0.4572 6.0241
49 3DC4 ADP 0.000002192 0.45034 6.0241
50 2IXE ATP 0.0003582 0.44326 6.0241
51 2YOH WMJ 0.0002228 0.41224 6.0241
52 3B5J 12D 0.0000303 0.41101 6.0241
53 4HI0 GDP 0.0000000818 0.61331 6.54762
54 3BFV ADP 0.000007625 0.5698 6.54762
55 2C9O ADP 0.0006335 0.44692 6.54762
56 1SKQ GDP 0.00000000003147 0.61048 6.62651
57 3NHB ADP 0.000005513 0.60279 6.62651
58 2RCN GDP 0.0000000001765 0.60115 6.62651
59 4KFU ACP 0.000002026 0.43779 6.62651
60 2ZR9 DTP 0.00003052 0.42971 6.62651
61 1IN4 ADP 0.000681 0.42032 6.62651
62 1G41 ADP 0.0003232 0.41551 6.62651
63 2JAQ DCP 0.002694 0.41316 6.62651
64 1JI0 ATP 0.000004019 0.60122 7.14286
65 1OS1 PYR 0.001737 0.43073 7.14286
66 1OS1 ATP 0.00183 0.42829 7.14286
67 1CR1 TTP 0.0008709 0.42258 7.14286
68 1OFH ADP 0.0004416 0.41198 7.14286
69 4HSE ADP 0.0002529 0.40856 7.14286
70 1JJV ATP 0.00006458 0.40575 7.14286
71 4RD0 GDP 0.000000000005896 0.75657 7.22892
72 1MKY GDP 0.0000000001252 0.60643 7.22892
73 1YRB GDP 0.000000003251 0.60567 7.22892
74 1SQ5 ADP 0.00001401 0.54942 7.22892
75 1G3Q ADP 0.00002059 0.54143 7.22892
76 2C04 GCP 0.00001057 0.53491 7.22892
77 2B8W ALF 5GP 0.000005379 0.5265 7.22892
78 4IDN GNP 0.00002285 0.50337 7.22892
79 1G6O ADP 0.000119 0.49903 7.22892
80 5LB3 ADP 0.0002993 0.49806 7.22892
81 1F5N GNP 0.000005254 0.49802 7.22892
82 5H56 TYD 0.00008057 0.48726 7.22892
83 5H56 ADP 0.00008057 0.48726 7.22892
84 2WOJ ADP ALF 0.00006772 0.45651 7.22892
85 3FWY ADP 0.00006308 0.455 7.22892
86 2QG6 NMN 0.0005212 0.44968 7.22892
87 3A4M ADP 0.000003197 0.44173 7.22892
88 2VVG ADP 0.0000007595 0.42675 7.22892
89 1F9V ADP 0.00001369 0.41781 7.22892
90 4TMK T5A 0.004851 0.4157 7.22892
91 2F5X ASP 0.02794 0.40551 7.22892
92 1CM0 COA 0.01541 0.40032 7.22892
93 1GXU 2HP 0.0005729 0.47856 7.69231
94 4D81 ADP 0.00041 0.46886 7.7381
95 4OI4 ATP 0.001598 0.42249 7.82609
96 2WIC GNP 0.0000000001209 0.79133 7.83133
97 4R98 GNH 0.000000007918 0.71583 7.83133
98 5HCN GCP 0.00000001645 0.6894 7.83133
99 1TQ4 GDP 0.00000002878 0.63271 7.83133
100 5L3V GDP 0.000001242 0.59151 7.83133
101 5I34 GDP 0.00001299 0.55098 7.83133
102 5GVR LMR 0.0002605 0.52088 7.83133
103 4ZNL BEF ADP 0.0001862 0.49575 7.83133
104 5BQ5 ADP BEF 0.0001789 0.49077 7.83133
105 5X40 ACP 0.0004208 0.44632 7.83133
106 1XMV ADP 0.00006112 0.42833 7.83133
107 2XAU ADP 0.0005854 0.40386 7.83133
108 1D2N ANP 0.002978 0.40256 8.08823
109 3KJI ADP 0.0000701 0.44777 8.33333
110 1XKV ATP 0.0001032 0.43443 8.33333
111 3QKT ANP 0.00104 0.43199 8.33333
112 1OXV ANP 0.00001432 0.42785 8.33333
113 4NZ6 DGL 0.02369 0.40801 8.33333
114 4GBM A3P 0.005012 0.40205 8.33333
115 2HF9 GSP 0.00000002291 0.6538 8.43373
116 3B9Q MLI 0.000001085 0.6493 8.43373
117 5FG3 GDP 0.0000000001134 0.59456 8.43373
118 5L3R GCP 0.00000131 0.53915 8.43373
119 4BQS ADP 0.00004032 0.5344 8.43373
120 1JWY GDP 0.0000003184 0.53222 8.43373
121 4XTR ADP 0.0001643 0.47675 8.43373
122 4R2I ANP 0.001284 0.47217 8.43373
123 3TMK T5A 0.0001979 0.46906 8.43373
124 4XTR ATP 0.0001617 0.46339 8.43373
125 1LVG ADP 0.0000004979 0.46281 8.43373
126 4XVU ATP 0.0001923 0.46029 8.43373
127 1JWY ADP 0.00002946 0.442 8.43373
128 4JBL MET 0.01953 0.41105 8.43373
129 2VF7 ADP 0.0003068 0.4075 8.43373
130 1QF9 C5P 0.003008 0.4283 8.76289
131 2GJ8 ALF GDP 0.0000000005919 0.64546 8.92857
132 1D2E GDP 0.000000006583 0.59065 8.92857
133 1QF5 GDP 0.0001098 0.50529 8.92857
134 4IEE AGS 0.0003688 0.49351 8.92857
135 1QF5 RPL 0.00559 0.45647 8.92857
136 1ZIN AP5 0.0008241 0.45638 8.92857
137 4MKF AP5 0.00125 0.44955 8.92857
138 4PJ3 ANP 0.007627 0.41087 8.92857
139 1B7T ADP 0.0001486 0.42787 8.97436
140 1WF3 GNP 0.0000000002234 0.71403 9.03614
141 5KSZ GCP 0.0000005345 0.60859 9.03614
142 4H1V GNP 0.000002261 0.5648 9.03614
143 4YMU ATP 0.00002677 0.55069 9.03614
144 4PFO ADP 0.00001231 0.51384 9.03614
145 2VB6 ADP BEF 0.000009936 0.51318 9.03614
146 2AWN ADP 0.0000003856 0.40916 9.03614
147 1KK8 BEF ADP 0.00001695 0.47363 9.09091
148 1G7S GDP 0.0000000005695 0.75918 9.52381
149 1SVI GDP 0.00000003325 0.52927 9.52381
150 4TTQ ATP 0.00005099 0.43094 9.52381
151 2JLR ANP 0.0001611 0.43086 9.52381
152 3BFX A3P 0.003838 0.41694 9.52381
153 2WHX ADP 0.00001671 0.40944 9.52381
154 5CK5 GDP 0.000000001189 0.56804 9.63855
155 2BEK ATP 0.000865 0.4372 9.63855
156 2XT3 ADP 0.000002804 0.42454 9.63855
157 4QRH 0O2 0.0008878 0.42169 9.63855
158 5AOG IAC 0.01013 0.41392 9.63855
159 3ZFD ANP 0.0000002443 0.52414 10.119
160 5KUT GDP 0.00000009716 0.53188 10.241
161 1IHU ADP 0.0003495 0.44963 10.241
162 1IHU AF3 0.0002798 0.44774 10.241
163 1XP8 AGS 0.00007517 0.41352 10.241
164 4U00 ADP 0.000001909 0.40771 10.241
165 3R7F CP 0.02861 0.40436 10.241
166 4PU6 ASP 0.01106 0.42387 10.687
167 1B0U ATP 0.0006516 0.40675 10.687
168 1M7G ADX 0.00003436 0.5047 10.7143
169 1M7G ADP 0.00003668 0.49995 10.7143
170 1M7G AV2 0.0000008279 0.47062 10.7143
171 2Q2Y MKR 0.0007987 0.4558 10.7143
172 2Q2Y ADP 0.001037 0.45201 10.7143
173 3UIE ANP 0.00004531 0.44252 10.7143
174 3COB ADP 0.000002948 0.42547 10.7143
175 1PUJ GNP 0.0000000001484 0.64853 10.8434
176 3A1S GDP 0.000002065 0.58914 10.8434
177 5L3S GNP 0.000005668 0.51406 10.8434
178 5L3W GDP 0.00001291 0.46907 10.8434
179 3FB4 AP5 0.0007591 0.45795 10.8434
180 5L3S G 0.008394 0.43431 10.8434
181 1RRC ADP 0.000000824 0.433 10.8434
182 1VHT BA3 0.0008875 0.40478 10.8434
183 1L2T ATP 0.001099 0.42216 11.3095
184 5GJC ATP 0.00003615 0.53672 11.9048
185 1P72 ADP 0.002348 0.42794 11.9048
186 1G6H ADP 0.0000006455 0.41792 11.9048
187 3MD0 GDP 0.0000000001164 0.59113 12.0482
188 1NN5 ANP 0.00008273 0.48846 12.0482
189 1W0J ADP 0.00009504 0.44003 12.0482
190 1ION ADP 0.000103 0.43311 12.0482
191 5TSH ANP 0.00004252 0.42899 12.0482
192 1W0J ADP BEF 0.002241 0.40185 12.0482
193 4MKG AP5 0.0008692 0.45536 12.4424
194 3FVQ ATP 0.0004957 0.43135 12.5
195 2Y65 ADP 0.000003323 0.42276 12.5
196 2KIN ADP 0.000001529 0.41668 12.5
197 1ZOY UQ1 0.02864 0.40121 12.5
198 4P4T GDP 0.0000009143 0.57524 12.6506
199 2ZFI ADP 0.000007854 0.56917 12.6506
200 3TK1 GDP 0.000000001122 0.55688 12.6506
201 4FRZ ADP 0.00001314 0.4177 12.6506
202 3H4S ADP 0.000004566 0.4173 12.6506
203 3P4X ADP 0.00002944 0.42403 13.0952
204 4B47 GDP 0.00000000002507 0.61112 13.2231
205 3WXM GTP 0.00000000006052 0.73446 13.253
206 2HT6 GDP 0.00000000001326 0.6176 13.253
207 2CJW GDP 0.000000000194 0.60175 13.253
208 1OE0 TTP 0.006544 0.40202 13.253
209 2QEN ADP 0.00009756 0.44601 13.6905
210 2QZ4 ADP 0.0001258 0.43173 13.6905
211 1T5C ADP 0.000001988 0.41566 13.6905
212 4AG5 ADP 0.000006252 0.59877 13.8554
213 5I0H ADP BEF 0.0000003595 0.5548 13.8554
214 2CHG ANP 0.0005698 0.4191 13.8554
215 4YS0 ADP 0.003161 0.4244 14.2857
216 1G7C 5GP 0.00000003013 0.53807 14.4578
217 2OFW ADX 0.00003471 0.51538 14.4578
218 4WOP CTP 0.000118 0.47815 14.4578
219 1X6V ADP 0.0001074 0.43525 14.4578
220 5N69 ADP 0.000004279 0.55926 15.0602
221 2BIF SIN 0.0008964 0.45813 15.0602
222 2BIF ANP 0.0004994 0.45813 15.0602
223 1DAR GDP 0.0000000004395 0.59292 15.4762
224 4GOX A3P 0.001264 0.42668 15.4762
225 3QF7 ANP 0.0004179 0.42807 15.6627
226 2ZPA ADP 0.0006228 0.42128 15.6627
227 1SES AMP 0.01442 0.41345 15.6627
228 3ZS9 ADP ALF 0.00005136 0.46071 15.7895
229 2V7Q ATP 0.00006683 0.43762 16
230 2CK3 ANP 0.002429 0.42563 16
231 2CK3 ADP 0.003801 0.407 16
232 3E70 GDP 0.000002125 0.48568 16.0714
233 1Z6T ADP 0.0004718 0.46129 16.0714
234 3BER AMP 0.01193 0.41334 16.0714
235 5M04 GDP 0.00000000002351 0.85466 16.2651
236 2PEZ DAT 0.00002738 0.51061 16.2651
237 2PEZ GGZ 0.00002738 0.43747 16.2651
238 3RLF ANP 0.0007698 0.43553 16.2651
239 1G8S MET 0.009206 0.42961 16.2651
240 1S3G AP5 0.0007474 0.45825 16.6667
241 5MZN ADP 0.005118 0.44118 16.6667
242 2NCD ADP 0.0000009882 0.64034 16.8675
243 2ZE7 DST 0.003235 0.41483 16.8675
244 2IYL GDP 0.000003651 0.47381 17.4699
245 4CVN ADP 0.00002381 0.56141 17.8571
246 4LC1 GDP 0.00000001049 0.70985 18.0723
247 1P9B GDP 0.00005625 0.45931 18.0723
248 1R6B ADP 0.0003689 0.40814 18.0723
249 2J5V PCA 0.03086 0.40283 18.0723
250 3CV2 OXL 0.03529 0.4001 18.4524
251 1W7J ADP BEF 0.000001628 0.57117 18.543
252 1M7B GTP 0.000000001253 0.69095 18.6747
253 1GWN GTP 0.0000000007241 0.66385 18.6747
254 4QOS ADP 0.0008226 0.45985 18.6747
255 2WKQ GTP 0.000000001241 0.67361 19.8795
256 2W2X GSP 0.0000000005188 0.6688 19.8795
257 2FJU GSP 0.0000000007705 0.66311 19.8795
258 3SBD GNP 0.000000001027 0.65018 19.8795
259 1RYH GNP 0.000000000535 0.61974 19.8795
260 1KK1 GNP 0.0000000001725 0.59101 19.8795
261 1HE1 GDP 0.0000006304 0.57536 19.8795
262 1HE1 AF3 0.00003299 0.55412 19.8795
263 1DS6 GDP 0.00000001585 0.5493 19.8795
264 1I4D GDP 0.0000000595 0.52177 19.8795
265 4WZA ADP 0.00008743 0.51853 20.2381
266 4WZA ACP 0.00008743 0.51853 20.2381
267 4UHO PLP 0.03066 0.40083 20.2381
268 1E96 GTP 0.00000000033 0.70384 20.4819
269 4U5X GNP 0.00000000123 0.64238 20.4819
270 2ZEJ GDP 0.0000001107 0.60143 20.4819
271 2CE7 ADP 0.0002198 0.41968 20.4819
272 2XTZ GSP 0.000000000001302 0.80375 21.6867
273 1AZT GSP 0.000000000003383 0.79675 21.6867
274 1CS4 GSP 0.00000000000237 0.71714 21.6867
275 3DEF GDP 0.00001114 0.47848 21.6867
276 1FNN ADP 0.0005637 0.45336 21.6867
277 3IIJ ADP 0.000002125 0.47109 22.0238
278 4QM7 GTP 0.00000715 0.45236 22.0238
279 1D5C GDP 0.000000007886 0.60102 22.2222
280 3GJ8 GDP 0.0000000001171 0.79199 22.2892
281 4HAT GNP 0.000000000004104 0.78994 22.2892
282 5UWP GNP 0.00000000000473 0.78735 22.2892
283 5UWI GNP 0.000000000004041 0.78683 22.2892
284 5UWT GNP 0.000000000004228 0.78601 22.2892
285 1IBR GNP 0.000000000005804 0.78026 22.2892
286 3GJ0 GDP 0.0000000005684 0.77182 22.2892
287 5UWU GNP 0.00000000000392 0.72347 22.2892
288 5DIF GNP 0.000000000004393 0.72177 22.2892
289 5UWO GNP 0.000000000004444 0.72159 22.2892
290 5UWJ GNP 0.000000000004458 0.72149 22.2892
291 5UWH GNP 0.000000000004573 0.72111 22.2892
292 5DI9 GNP 0.000000000005846 0.70204 22.2892
293 5UWS GNP 0.000000000006123 0.70143 22.2892
294 1MH1 GNP 0.0000000001003 0.67443 22.2892
295 3CH5 GDP 0.00000000009291 0.62797 22.2892
296 3GJ5 GDP 0.000000000158 0.62159 22.2892
297 5BXQ GDP 0.0000000001984 0.61867 22.2892
298 3GJ3 GDP 0.0000000003669 0.59565 22.2892
299 3GJ7 GDP 0.0000000004741 0.5926 22.2892
300 3GJ4 GDP 0.0000000005815 0.59066 22.2892
301 3EC1 GDP 0.000000004686 0.5767 22.2892
302 1G4U GDP 0.0000008519 0.57658 22.2892
303 1G4U AF3 0.0001286 0.5283 22.2892
304 4R43 GDP 0.0002097 0.49935 22.8916
305 1ZUI SKM 0.0000969 0.4917 22.8916
306 3W5J GDP 0.00000001336 0.48613 22.8916
307 3REF GDP 0.00000001538 0.63635 23.494
308 2QN6 GDP 0.00000000003766 0.60638 23.6559
309 3M1I GTP 0.000000000004008 0.78698 24.0964
310 4NON GDP 0.0000001645 0.54441 25.3012
311 1K6M AGS 0.0001947 0.46007 25.3012
312 1Z2A GDP 0.00000001065 0.63524 25.9036
313 4P32 ADP 0.0007917 0.42893 25.9036
314 3FIU POP 0.03593 0.40089 25.9036
315 3CX8 GSP 0.000000000002397 0.80307 26.1905
316 3AB3 GDP 0.000000004624 0.62869 26.1905
317 1A4R GDP 0.00000000755 0.61411 26.506
318 1A4R GNH 0.000000009162 0.60187 26.506
319 1GRN GDP 0.00000006402 0.56854 26.506
320 2NGR GDP 0.00000004421 0.54548 26.506
321 4DID GDP 0.00000005041 0.5412 26.506
322 4ITR GDP 0.0000007514 0.53636 26.506
323 2NGR AF3 0.0000001832 0.48866 26.506
324 1GRN AF3 0.0000003573 0.48159 26.506
325 1BG2 ADP 0.0000008387 0.42295 26.7857
326 1TAD GDP 0.000000000009637 0.77757 27.1084
327 1TAD ALF 0.000000000009637 0.6833 27.1084
328 1NF3 GNP 0.0000000005765 0.65965 27.1084
329 1GOT GDP 0.00000000871 0.62903 27.1084
330 3ZIA ATP 0.00006137 0.43305 27.5362
331 3ZIA ADP 0.0001887 0.42914 27.5362
332 2GCO GNP 0.000000001172 0.63185 27.8607
333 2GCN GDP 0.00000006021 0.59622 27.8607
334 1FP6 ADP 0.0002076 0.42884 27.9762
335 1X1R GDP 0.000000003171 0.66589 28.0899
336 1BH2 GSP 0.000000000004211 0.79274 28.3133
337 3T12 GDP ALF 0.00000000001489 0.7627 28.3133
338 1FQJ ALF 0.00000003658 0.71528 28.3133
339 1FQK ALF 0.0000001079 0.69646 28.3133
340 2ODE ALF GDP 0.000000000006096 0.68941 28.3133
341 5KDO GDP 0.000000002953 0.67502 28.3133
342 1FQJ GDP 0.000000001474 0.67055 28.3133
343 1Y3A GDP 0.000000002662 0.65999 28.3133
344 1FQK GDP 0.000000002867 0.65867 28.3133
345 1GP2 GDP 0.0000000131 0.63155 28.3133
346 3T1O GDP 0.0000000004827 0.61776 28.3133
347 5UQW GDP 0.000000001779 0.67037 28.5714
348 1NRJ GTP 0.000000000009543 0.73692 28.8991
349 1SVK ALF GDP 0.000000000002823 0.80326 28.9157
350 3ZQ6 ADP ALF 0.00004381 0.49292 28.9157
351 5TAR GDP 0.000000001165 0.72188 29.1892
352 5TB5 GDP 0.0000000006688 0.61541 29.1892
353 2A5J GDP 0.000000003654 0.70963 30.1205
354 3Q85 GNP 0.000000000139 0.60638 30.7229
355 5HR5 ADP 0.0002324 0.43048 30.7229
356 5HR5 FLC 0.003023 0.42323 30.7229
357 4HDO GNP 0.00000000004984 0.74124 31.3253
358 1Z0A GDP 0.0000000002436 0.62822 31.3253
359 1Z0F GDP 0.0000000001526 0.62099 31.3253
360 1H65 GDP 0.00009177 0.46819 31.3253
361 5DHF GNP 0.000000000004441 0.72163 31.5789
362 1NVV GNP 0.00000000004597 0.74271 31.9277
363 3DDC GNP 0.0000000001188 0.72548 31.9277
364 2UZI GTP 0.000000000179 0.71488 31.9277
365 1XTQ GDP 0.00000000162 0.66886 31.9277
366 1WQ1 AF3 0.0000009117 0.64443 31.9277
367 3KUD GDP 0.00000001397 0.61166 31.9277
368 3T5G GDP 0.000000001887 0.59932 31.9277
369 1WQ1 GDP 0.000000119 0.59216 31.9277
370 1CLU DBG 0.00000001971 0.48059 31.9277
371 5O2T GSP 0.0000000002822 0.65822 31.9527
372 1GUA GNP 0.00000000007654 0.67802 32.0988
373 2BME GNP 0.00000000000349 0.78596 32.5301
374 1NVU GTP 0.00000000006747 0.73575 32.5301
375 4C4P GNP 0.00000000009335 0.72986 32.5301
376 2D7C GTP 0.0000000001385 0.71951 32.5301
377 1OIV GDP 0.000000004527 0.65658 32.5301
378 2F9L GDP 0.00000008467 0.59824 32.5301
379 1Z0K GTP 0.000000000005617 0.76996 33.1325
380 1OIX GDP 0.0000000003558 0.70249 33.1325
381 2HV8 GTP 0.0000000005733 0.69388 33.1325
382 4DSU GDP 0.000000001566 0.6787 33.1325
383 1U8Z GDP 0.000000008827 0.63859 33.1325
384 5UFQ GNP 0.000000003381 0.62862 33.1325
385 2A9K GDP 0.00000001048 0.59494 33.1325
386 1YQT ADP 0.00002342 0.40766 33.1325
387 2OM2 GDP 0.000000004035 0.66922 33.3333
388 1KAO GDP 0.0000000181 0.58596 33.5329
389 1VG8 GNP 0.00000000002984 0.75055 33.7349
390 2C5L GTP 0.00000000006442 0.73659 33.7349
391 4K81 GTP 0.0000000002152 0.71774 33.7349
392 1ZC3 GNP 0.000000001063 0.68572 33.7349
393 1VG0 GDP 0.00000000913 0.58642 33.7349
394 1CXZ GSP 0.0000000001838 0.69781 34.3373
395 1VG1 GDP 0.0000000006724 0.59813 34.3373
396 1VG9 GDP 0.000000001345 0.59085 34.3373
397 4D0N GDP 0.00000001844 0.54415 34.3373
398 1Z06 GNP 0.0000000000007012 0.81109 34.9398
399 1R2Q GNP 0.00000000002361 0.77529 34.9398
400 2WJG GDP 0.0000000007737 0.76526 34.9398
401 2G77 GDP 0.000000000124 0.75495 34.9398
402 1EK0 GNP 0.00000000004212 0.741 34.9398
403 1TU3 GNP 0.00000000005354 0.73667 34.9398
404 2G77 AF3 0.0000006826 0.64815 34.9398
405 2WJH GDP 0.0000000008713 0.60161 34.9398
406 1Z08 GNP 0.00000007112 0.60135 34.9398
407 5XCO GDP 0.00000001142 0.58415 34.9398
408 1G16 GDP 0.0000002547 0.57053 34.9398
409 2WJH FLC 0.0000002302 0.52734 34.9398
410 1YVD GNP 0.00000000003328 0.74525 35.5422
411 3MJH GTP 0.00000000001264 0.72251 35.5422
412 3RWO GDP 0.00000001263 0.63806 35.5422
413 1Z0J GTP 0.00000000001606 0.7038 36.1446
414 1TX4 ALF GDP 0.000000001124 0.67538 36.1446
415 1KY3 GDP 0.0000000228 0.57267 36.1446
416 1OW3 GDP 0.00000007858 0.56625 36.1446
417 5HPY GDP 0.00000007826 0.56603 36.1446
418 5IRC GDP 0.0000001358 0.54099 36.1446
419 1KMQ GNP 0.0000000001593 0.71026 36.747
420 5UWR GNP 0.000000000004485 0.7214 37.037
421 1YZN GNP 0.00000000006208 0.68153 37.3494
422 2BCG GDP 0.00000003568 0.63677 37.3494
423 1S8F GDP 0.0000000006187 0.69848 37.9518
424 5UWW GNP 0.000000000004248 0.72225 38.0952
425 3QBT GNP 0.000000000004145 0.74034 38.5542
426 3RAB GNP 0.00000000004126 0.74137 39.1566
427 3BC1 GNP 0.0000000001513 0.71792 39.759
428 1WA5 GTP 0.00000000001038 0.65379 40.9639
429 1LFD GNP 0.00000000007698 0.73011 43.7126
430 2FH5 GTP 0.000000000004238 0.74868 43.9759
431 3PQC GDP 0.0000007758 0.60104 43.9759
432 5UWQ GNP 0.000000000004494 0.72139 45.4545
433 4DCT GDP 0.000000002877 0.58099 45.7831
434 1M2O GNP 0.000000000006889 0.77368 46.3855
435 1F6B GDP 0.00000000004681 0.63592 46.988
Pocket No.: 2; Query (leader) PDB : 2J59; Ligand: GTP; Similar sites found: 4
This union binding pocket(no: 2) in the query (biounit: 2j59.bio6) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1XEX ATP 0.00276 0.40016 5.42169
2 4TQK NAG 0.03039 0.4027 6.54762
3 1QHH ATP 0.01622 0.4029 12.0482
4 2Z48 A2G 0.02733 0.40898 22.2892
Pocket No.: 3; Query (leader) PDB : 2J59; Ligand: GTP; Similar sites found: 3
This union binding pocket(no: 3) in the query (biounit: 2j59.bio3) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3GUZ PAF 0.02517 0.40401 2.97619
2 1GS5 NLG 0.01161 0.40052 10.119
3 1V6A TRE 0.03358 0.40131 14.2857
Pocket No.: 4; Query (leader) PDB : 2J59; Ligand: GTP; Similar sites found: 1
This union binding pocket(no: 4) in the query (biounit: 2j59.bio5) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2Z48 NGA 0.01404 0.4259 22.2892
Pocket No.: 5; Query (leader) PDB : 2J59; Ligand: GTP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 2j59.bio4) has 24 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 2J59; Ligand: GTP; Similar sites found: 9
This union binding pocket(no: 6) in the query (biounit: 2j59.bio2) has 23 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3B7G ANP 0.0008676 0.40089 3.57143
2 2IS6 ADP 0.0003252 0.4059 5.35714
3 1W5T ANP 0.003195 0.40666 5.42169
4 3DKP ADP 0.0003975 0.40593 6.0241
5 1NY5 ADP 0.002095 0.40357 6.62651
6 4O48 ASP 0.01323 0.42076 8.33333
7 5TSH ADP 0.00009624 0.40311 12.0482
8 4IHQ ADP 0.0001738 0.40771 13.8554
9 2F3R G5P 0.01019 0.40348 14.881
Feedback