Receptor
PDB id Resolution Class Description Source Keywords
2NPX 2.4 Å EC: 1.11.1.1 NADH BINDING SITE AND CATALYSIS OF NADH PEROXIDASE ENTEROCOCCUS FAECALIS OXIDOREDUCTASE(H2O2(A))
Ref.: NADH BINDING SITE AND CATALYSIS OF NADH PEROXIDASE. EUR.J.BIOCHEM. V. 211 221 1993
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
FAD A:449;
Valid;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
NAD A:818;
Valid;
none;
submit data
663.425 C21 H27 N7 O14 P2 c1cc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2NPX 2.4 Å EC: 1.11.1.1 NADH BINDING SITE AND CATALYSIS OF NADH PEROXIDASE ENTEROCOCCUS FAECALIS OXIDOREDUCTASE(H2O2(A))
Ref.: NADH BINDING SITE AND CATALYSIS OF NADH PEROXIDASE. EUR.J.BIOCHEM. V. 211 221 1993
Members (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1NHS - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 1F8W - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 2NPX - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
4 1NHP - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 1NHR - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 1NPX - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 1NHQ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 1NHS - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 1F8W - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 2NPX - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
4 1NHP - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 1NHR - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 1NPX - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
7 1NHQ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 177 families.
1 5VN0 - NAI C21 H29 N7 O14 P2 c1nc(c2c(n....
2 5VOH - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
3 5ER0 - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
4 1NHS - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
5 1F8W - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
6 2NPX - NAD C21 H27 N7 O14 P2 c1cc(c[n+]....
7 1NHP - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
8 1NHR - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
9 1NPX - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
10 1NHQ - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
11 2CDU - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 119
No: Ligand ECFP6 Tc MDL keys Tc
1 FAS 1 1
2 FAD 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 DAL FAD PER 0.772414 0.951807
7 FAE 0.751773 0.987654
8 SFD 0.651007 0.860215
9 FDA 0.641892 0.906977
10 FNK 0.602564 0.876405
11 62F 0.572327 0.939024
12 F2N 0.566265 0.886364
13 FMN 0.543307 0.876543
14 FA9 0.526316 0.939759
15 6YU 0.516304 0.860215
16 CNV FAD 0.511905 0.908046
17 P6G FDA 0.511628 0.908046
18 FAD NBT 0.508876 0.83871
19 A2D 0.504065 0.875
20 P5F 0.491329 0.941176
21 FAD CNX 0.488506 0.8125
22 APR 0.488372 0.851852
23 AR6 0.488372 0.851852
24 AGS 0.484615 0.811765
25 SAP 0.484615 0.811765
26 M33 0.484375 0.864198
27 BA3 0.484127 0.875
28 FAD NBA 0.480663 0.802083
29 ATP 0.48062 0.851852
30 B4P 0.480315 0.875
31 ADP 0.480315 0.851852
32 AP5 0.480315 0.875
33 ANP 0.477273 0.831325
34 AQP 0.476923 0.851852
35 5FA 0.476923 0.851852
36 48N 0.469388 0.902439
37 OAD 0.467626 0.876543
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AD9 0.462121 0.831325
41 3OD 0.460993 0.876543
42 RBF 0.460938 0.790123
43 FB0 0.460606 0.835165
44 139 0.460526 0.858824
45 AP0 0.46 0.835294
46 A22 0.459854 0.864198
47 ACP 0.458015 0.853659
48 8QN 0.456522 0.864198
49 PRX 0.454545 0.831325
50 A1R 0.453237 0.86747
51 G3A 0.452055 0.902439
52 T5A 0.45098 0.872093
53 G5P 0.44898 0.902439
54 ATF 0.448529 0.821429
55 50T 0.44697 0.819277
56 ACQ 0.444444 0.853659
57 PAJ 0.442857 0.847059
58 ADQ 0.442857 0.853659
59 5AL 0.441176 0.864198
60 ADX 0.439394 0.775281
61 CA0 0.439394 0.853659
62 A4P 0.437909 0.831461
63 25L 0.4375 0.864198
64 P33 FDA 0.436464 0.817204
65 5SV 0.435714 0.793103
66 TXE 0.434211 0.890244
67 OMR 0.434211 0.818182
68 ABM 0.434109 0.829268
69 A 0.433071 0.82716
70 AMP 0.433071 0.82716
71 4AD 0.432624 0.855422
72 ADJ 0.432258 0.818182
73 BIS 0.430556 0.802326
74 SRA 0.429688 0.788235
75 AFH 0.42953 0.825581
76 TXD 0.427632 0.890244
77 NXX 0.427632 0.865854
78 UP5 0.427632 0.878049
79 DND 0.427632 0.865854
80 6V0 0.427632 0.857143
81 SRP 0.42446 0.843373
82 PR8 0.423611 0.837209
83 TAT 0.423358 0.821429
84 AMO 0.422535 0.865854
85 PTJ 0.42069 0.835294
86 FYA 0.42069 0.864198
87 TXA 0.42069 0.865854
88 CNA 0.420382 0.865854
89 00A 0.41958 0.823529
90 AHX 0.41958 0.835294
91 MAP 0.41844 0.811765
92 NAI 0.418301 0.845238
93 AU1 0.41791 0.831325
94 AP2 0.416667 0.843373
95 A12 0.416667 0.843373
96 25A 0.415493 0.851852
97 AMP MG 0.415385 0.785714
98 COD 0.415094 0.842697
99 ADP BEF 0.414815 0.77907
100 BEF ADP 0.414815 0.77907
101 4TC 0.412903 0.879518
102 APC 0.411765 0.843373
103 NB8 0.410959 0.835294
104 ME8 0.410959 0.806818
105 1ZZ 0.410959 0.806818
106 4UW 0.409091 0.825581
107 NAX 0.409091 0.837209
108 RBY 0.408759 0.843373
109 ADV 0.408759 0.843373
110 ADP MG 0.407407 0.797619
111 P1H 0.405882 0.818182
112 OOB 0.405594 0.864198
113 A A 0.40411 0.829268
114 LAD 0.40411 0.825581
115 UPA 0.403846 0.86747
116 4UU 0.401316 0.833333
117 A3D 0.401235 0.876543
118 DLL 0.4 0.864198
119 XAH 0.4 0.806818
Ligand no: 2; Ligand: NAD; Similar ligands found: 220
No: Ligand ECFP6 Tc MDL keys Tc
1 A3D 0.872727 0.986111
2 NAD IBO 0.845455 0.933333
3 NHD 0.821429 0.972222
4 NAP 0.811966 0.986111
5 NAJ PYZ 0.803419 0.910256
6 NFD 0.791304 0.946667
7 NXX 0.765766 0.972603
8 DND 0.765766 0.972603
9 ZID 0.737705 0.986111
10 NAQ 0.729508 0.934211
11 NAE 0.721311 0.959459
12 NA0 0.712 0.972603
13 TAP 0.704 0.921053
14 AMP NAD 0.696 0.945946
15 NDE 0.689922 0.972603
16 NAJ 0.683333 0.972222
17 NDC 0.679389 0.934211
18 NDO 0.674603 0.958904
19 N01 0.656 0.972222
20 CNA 0.642276 0.972603
21 NBP 0.621212 0.922078
22 NAD BBN 0.609929 0.876543
23 8ID 0.609756 0.922078
24 NAD CJ3 0.601399 0.845238
25 ADP MG 0.579439 0.918919
26 A2D 0.576923 0.958333
27 ADP 0.575472 0.931507
28 NGD 0.574803 0.922078
29 BEF ADP 0.574074 0.894737
30 ADP BEF 0.574074 0.894737
31 BA3 0.566038 0.958333
32 NAD NDT 0.565789 0.755319
33 M33 0.564815 0.918919
34 ADP PO3 0.563636 0.957747
35 B4P 0.560748 0.958333
36 AP5 0.560748 0.958333
37 ATP MG 0.558559 0.918919
38 AN2 0.555556 0.918919
39 GAP 0.553571 0.932432
40 OOB 0.551724 0.972222
41 CA0 0.550459 0.932432
42 ATP 0.545455 0.931507
43 ACP 0.545455 0.906667
44 NAD TDB 0.544872 0.70297
45 ADP ALF 0.54386 0.883117
46 ALF ADP 0.54386 0.883117
47 5FA 0.540541 0.931507
48 AQP 0.540541 0.931507
49 APR 0.540541 0.931507
50 AR6 0.540541 0.931507
51 ANP MG 0.53913 0.907895
52 VO4 ADP 0.53913 0.945205
53 ADP VO4 0.53913 0.945205
54 AGS 0.535714 0.883117
55 SAP 0.535714 0.883117
56 AD9 0.535714 0.906667
57 WAQ 0.533333 0.896104
58 ABM 0.53271 0.905405
59 00A 0.529412 0.921053
60 DLL 0.529412 0.972222
61 ANP 0.526316 0.906667
62 NJP 0.526316 0.959459
63 ACQ 0.526316 0.906667
64 OAD 0.525 0.932432
65 AMP MG 0.523364 0.905405
66 ADX 0.522523 0.839506
67 5AL 0.521739 0.945205
68 A1R 0.521008 0.871795
69 9SN 0.520325 0.909091
70 AMP 0.518868 0.930556
71 A 0.518868 0.930556
72 50T 0.517857 0.893333
73 ATF 0.517241 0.894737
74 DAL AMP 0.516949 0.945205
75 3OD 0.516393 0.932432
76 1ZZ 0.516393 0.851852
77 SON 0.513514 0.92
78 PRX 0.513274 0.881579
79 SRP 0.512821 0.92
80 ADP BMA 0.512397 0.932432
81 3UK 0.512397 0.958904
82 MYR AMP 0.512195 0.851852
83 NAJ PZO 0.510949 0.909091
84 NMN 0.509434 0.875
85 AMP DBH 0.507937 0.906667
86 A22 0.504202 0.945205
87 FA5 0.504 0.945946
88 ATP A A A 0.504 0.971831
89 TYR AMP 0.5 0.945946
90 8QN 0.5 0.945205
91 NAX 0.496183 0.886076
92 PR8 0.495935 0.8625
93 PAJ 0.495868 0.873418
94 4AD 0.495868 0.933333
95 AMO 0.495868 0.92
96 ADQ 0.495868 0.932432
97 A12 0.495495 0.894737
98 AP2 0.495495 0.894737
99 ALF ADP 3PG 0.492424 0.873418
100 LA8 ALF 3PG 0.492424 0.873418
101 AHZ 0.492308 0.851852
102 YAP 0.492063 0.933333
103 FYA 0.491935 0.918919
104 AHX 0.491803 0.884615
105 4UU 0.488372 0.933333
106 5SV 0.487603 0.8375
107 TAT 0.487179 0.894737
108 APC 0.486957 0.894737
109 SRA 0.486239 0.881579
110 NAI 0.484848 0.921053
111 6V0 0.484848 0.909091
112 GTA 0.484615 0.898734
113 A A 0.483871 0.958333
114 LAD 0.483871 0.873418
115 AU1 0.482456 0.906667
116 TXE 0.481203 0.921053
117 AF3 ADP 3PG 0.481203 0.873418
118 OMR 0.481203 0.841463
119 LAQ 0.480916 0.851852
120 G3A 0.48062 0.909091
121 TXA 0.48 0.92
122 NB8 0.48 0.884615
123 ME8 0.48 0.851852
124 BIS 0.48 0.871795
125 PTJ 0.48 0.884615
126 139 0.477941 0.886076
127 LPA AMP 0.477273 0.851852
128 AR6 AR6 0.476923 0.958333
129 G5P 0.476923 0.909091
130 AFH 0.476923 0.873418
131 25L 0.47619 0.945205
132 25A 0.47541 0.958333
133 DZD 0.47482 0.897436
134 TXD 0.473684 0.921053
135 4UV 0.472868 0.933333
136 TYM 0.470149 0.945946
137 ADV 0.470085 0.894737
138 RBY 0.470085 0.894737
139 ARG AMP 0.469697 0.841463
140 4TA 0.467626 0.864198
141 48N 0.466165 0.884615
142 XAH 0.465116 0.851852
143 4UW 0.462687 0.897436
144 M24 0.461538 0.886076
145 IOT 0.459854 0.821429
146 T5A 0.456522 0.853659
147 EAD 0.455782 0.886076
148 MAP 0.455285 0.883117
149 BT5 0.453901 0.821429
150 A4P 0.452555 0.833333
151 UP5 0.451852 0.933333
152 PAP 0.445378 0.917808
153 AP0 0.445255 0.884615
154 4TC 0.445255 0.909091
155 YLP 0.444444 0.831325
156 P1H 0.443709 0.864198
157 AOC 0.442478 0.810811
158 Z5A 0.439189 0.833333
159 2A5 0.436975 0.857143
160 G A A A 0.43662 0.909091
161 COD 0.43662 0.802326
162 ADJ 0.435714 0.841463
163 YLC 0.434783 0.851852
164 YLB 0.434783 0.831325
165 U A G G 0.433566 0.921053
166 ATR 0.433333 0.90411
167 7MD 0.432836 0.851852
168 G5A 0.429752 0.790698
169 PO4 PO4 A A A A PO4 0.429688 0.943662
170 TAD 0.42963 0.873418
171 5AS 0.42735 0.770115
172 BTX 0.426573 0.831325
173 YLA 0.425532 0.831325
174 DSZ 0.425197 0.790698
175 NCN 0.424779 0.805556
176 UPA 0.42446 0.921053
177 VMS 0.424 0.8
178 54H 0.424 0.8
179 N0B 0.422819 0.853659
180 6AD 0.422764 0.85
181 AYB 0.422535 0.821429
182 7D3 0.422414 0.844156
183 YLY 0.421769 0.821429
184 TSB 0.420635 0.809524
185 ODP 0.41958 0.922078
186 AV2 0.419355 0.855263
187 FB0 0.419355 0.775281
188 A5A 0.419355 0.819277
189 NNR 0.419048 0.739726
190 A A A 0.418605 0.918919
191 LEU LMS 0.418605 0.793103
192 649 0.417266 0.775281
193 NMN AMP PO4 0.416667 0.933333
194 SSA 0.416 0.790698
195 P5A 0.415385 0.755556
196 LSS 0.414062 0.772727
197 A2R 0.412698 0.918919
198 52H 0.412698 0.790698
199 JB6 0.412214 0.896104
200 5N5 0.411215 0.783784
201 YSA 0.410448 0.811765
202 5CA 0.409449 0.790698
203 53H 0.409449 0.790698
204 ITT 0.408333 0.878378
205 7D4 0.408333 0.844156
206 NA7 0.407692 0.894737
207 5CD 0.407407 0.794521
208 0WD 0.406897 0.909091
209 A3P 0.40678 0.930556
210 AVV 0.40625 0.860759
211 RAB 0.40566 0.808219
212 ADN 0.40566 0.808219
213 XYA 0.40566 0.808219
214 FDA 0.405063 0.823529
215 GSU 0.40458 0.790698
216 7MC 0.404255 0.831325
217 NSS 0.403101 0.811765
218 6FA 0.402516 0.853659
219 NVA LMS 0.4 0.793103
220 PPS 0.4 0.817073
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2NPX; Ligand: FAD; Similar sites found: 327
This union binding pocket(no: 1) in the query (biounit: 2npx.bio2) has 39 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2BRY FAD 0.00000003604 0.54775 1.34228
2 3WE0 FAD 0.000007791 0.49341 1.34228
3 1Z44 NPO 0.01591 0.45952 1.47929
4 1Z44 FMN 0.004825 0.42011 1.47929
5 1PN0 IPH 0.00000005228 0.57849 1.566
6 1PN0 FAD 0.000000048 0.5784 1.566
7 1M2W NAD 0.005733 0.41535 1.566
8 4MO2 FDA 0.000001555 0.50943 1.63043
9 4MO2 FAD 0.000001957 0.50041 1.63043
10 4KGD TDP 0.0006309 0.41294 1.78971
11 4KGD FAD 0.001725 0.40108 1.78971
12 1N4W FAD 0.000005452 0.49894 2.01342
13 2R0N TGC 0.004046 0.41024 2.03046
14 4DMG SAM 0.001533 0.47218 2.03562
15 3SJU NDP 0.004764 0.40057 2.15054
16 2Q37 3AL 0.001154 0.47285 2.20994
17 1E6W NAD 0.002784 0.41199 2.30769
18 1Y8Q ATP 0.00002298 0.42198 2.31214
19 3SHR CMP 0.001951 0.44541 2.34114
20 2Z3Y F2N 0.0000001754 0.55223 2.46085
21 2WET FAD 0.000001762 0.51362 2.46085
22 4E28 0MZ 0.009544 0.43039 2.46154
23 4E28 9MZ 0.01516 0.42619 2.46154
24 4DPL NAP 0.001986 0.41769 2.50696
25 1SS4 GSH 0.0001563 0.59004 2.61438
26 1SS4 CIT 0.0004788 0.54169 2.61438
27 3NYC FAD 0.000006863 0.50385 2.62467
28 1GTE FAD 0.00000005089 0.59186 2.68456
29 2B4R NAD 0.0005979 0.40359 2.89855
30 4EIP FAD 0.0000003437 0.54326 2.90828
31 4EIP K2C 0.0000006961 0.53502 2.90828
32 3Q9T FAY 0.0004465 0.42496 2.90828
33 1TV5 ORO 0.003884 0.41782 2.93454
34 3G2O SAM 0.002 0.44919 3.01003
35 2GJN FMN 0.0004398 0.42356 3.04878
36 2GJN NIS 0.001129 0.40429 3.04878
37 2B9W FAD 0.000001018 0.53884 3.06604
38 1PEA ACM 0.004569 0.46469 3.11688
39 3QJ4 FAD 0.0000003054 0.52782 3.21637
40 1HYH NAD 0.0005083 0.40643 3.23625
41 4MP8 MLI 0.00003457 0.41957 3.24484
42 3MAG 3MA 0.04268 0.42686 3.25733
43 3OZ2 FAD 0.000000004504 0.60366 3.27456
44 3GDH SAH 0.00194 0.4324 3.3195
45 1Q9I FAD 0.00000006626 0.46582 3.3275
46 1V8B NAD 0.001059 0.40813 3.3557
47 3G5S FAD 0.0000000177 0.57719 3.386
48 4TM3 FAD 0.000002851 0.53317 3.386
49 3S9K CIT 0.002614 0.50644 3.38983
50 1MV8 NAD 0.0002863 0.40038 3.44037
51 1OC2 NAD 0.005718 0.40012 3.44828
52 1KNR FAD 0.0000001894 0.54634 3.57942
53 1HDG NAD 0.001345 0.43594 3.61446
54 3CIF NAD 0.0003605 0.40441 3.62117
55 1CER NAD 0.0008555 0.44087 3.62538
56 1O68 KIV 0.03837 0.41218 3.63636
57 1D4D FAD 0.00000002276 0.58389 3.67133
58 3DMH SAM 0.003678 0.43 3.67454
59 3DMH GMP 0.006484 0.40246 3.67454
60 1MXI SAH 0.001068 0.43293 3.75
61 2GN4 NDP 0.01081 0.40633 3.77907
62 2R4J FAD 0.00001476 0.49277 3.79242
63 4B63 FAD 0.00000006407 0.5662 3.80313
64 4B63 ORN 0.00000006407 0.5662 3.80313
65 4B63 NAP 0.00000006976 0.5662 3.80313
66 3S5W FAD 0.0000001388 0.52003 3.80313
67 3UOY NAP 0.00001232 0.50813 3.80313
68 1COY FAD 0.000006804 0.49284 3.80313
69 1COY AND 0.00003594 0.48255 3.80313
70 1KY8 NAP 0.002914 0.40411 3.80313
71 4NTC FAD 0.00000000239 0.61523 3.8806
72 1ZK4 AC0 0.0008604 0.41427 3.98406
73 2Y6Q I7T 0.000002611 0.51431 4.0201
74 2Y6Q FAD 0.0000004279 0.5096 4.0201
75 4AP3 NAP 0.000008672 0.50842 4.02685
76 4AT0 FAD 0.00002738 0.47862 4.02685
77 2ZV2 609 0.03858 0.40454 4.02685
78 4EUE NAI 0.0009737 0.40031 4.06699
79 4C3Y FAD 0.000001868 0.51273 4.15094
80 4C3Y ANB 0.000005191 0.50354 4.15094
81 3OJO NAD 0.00007822 0.4044 4.17633
82 1DLJ NAI 0.0007417 0.42861 4.22886
83 1DLJ UGA 0.001991 0.41297 4.22886
84 3AXB PRO 0.000003819 0.50311 4.24107
85 3AXB FAD 0.000003101 0.49898 4.24107
86 2ZXI FAD 0.000000001997 0.61022 4.25056
87 1QO8 FAD 0.00000001984 0.58436 4.25056
88 2E5V FAD 0.0000001111 0.55931 4.25056
89 1H82 GZZ 0.0000008531 0.54713 4.25056
90 1H82 FAD 0.000001458 0.53418 4.25056
91 2VVM FAD 0.0000006797 0.52676 4.25056
92 2VVL FAD 0.000001003 0.5223 4.25056
93 4IV9 FAD 0.000001052 0.52007 4.25056
94 2AQJ FAD 0.000005191 0.51576 4.25056
95 2AQJ TRP 0.000004965 0.51547 4.25056
96 4MIG G3F 0.000006174 0.50322 4.25056
97 3QVP FAD 0.00008194 0.45692 4.25056
98 1Y42 TYR 0.01966 0.41121 4.33673
99 1I8T FAD 0.000001298 0.51532 4.35967
100 3FPF MTA 0.001827 0.40463 4.36242
101 5TUF FAD 0.0003845 0.47225 4.40098
102 3E1T FAD 0.000000005088 0.60712 4.47427
103 4FWE FAD 0.00000005854 0.56924 4.47427
104 2GMH FAD 0.00000005089 0.53587 4.47427
105 1VQW FAD 0.0000004598 0.51167 4.47427
106 2GVC FAD 0.0000004906 0.51062 4.47427
107 2GV8 FAD 0.000000825 0.50738 4.47427
108 3NKS FAD 0.000004175 0.49448 4.47427
109 3FC4 EDO 0.0003909 0.40851 4.47427
110 2WQ4 SFU 0.03621 0.42183 4.48718
111 1BW9 NAD 0.001549 0.4432 4.49438
112 2JCB ADP 0.02421 0.4115 4.5
113 1C1X NAD 0.001299 0.43347 4.50704
114 3TLJ SAH 0.00848 0.40802 4.55764
115 2DPY ADP 0.0397 0.41136 4.56621
116 3GF4 UPG 0.000004649 0.51653 4.61538
117 3GF4 FAD 0.000006235 0.50867 4.61538
118 2AHR NAP 0.0006944 0.40476 4.6332
119 2DKH FAD 0.00000002974 0.5509 4.69799
120 3AYI HCI 0.000001137 0.53476 4.69799
121 3AYI FAD 0.000001056 0.53476 4.69799
122 2DKH 3HB 0.0000003689 0.53453 4.69799
123 2RGO FAD 0.00001073 0.4802 4.69799
124 2RGH FAD 0.00002364 0.47236 4.69799
125 3GMB FAD 0.00000008489 0.5402 4.81928
126 3GFB NAD 0.003546 0.413 4.85714
127 3IHG FAD 0.000000004694 0.5547 4.9217
128 1RP0 AHZ 0.0000001573 0.52118 4.92958
129 2JJQ SAH 0.001445 0.46868 4.94118
130 3HDY FAD 0.000002908 0.52716 5.03778
131 3HDY GDU 0.000003354 0.52582 5.03778
132 3HDY FDA 0.000003159 0.52582 5.03778
133 2Q1S NAI 0.002173 0.40608 5.03979
134 4J36 1HR 0.000000342 0.54187 5.06024
135 4J36 FAD 0.00000008116 0.53688 5.06024
136 1JQ3 AAT 0.001963 0.41037 5.06757
137 1YY5 FAD 0.0000000366 0.57811 5.14541
138 4DSG FAD 0.0000006978 0.55144 5.14541
139 1RSG FAD 0.0000001902 0.54944 5.14541
140 4DSG UDP 0.000001508 0.53682 5.14541
141 5TS5 FAD 0.004564 0.40963 5.14541
142 4USR FAD 0.000001443 0.49579 5.26316
143 5A2J ALA PRO ASP THR ARG PRO 0.02624 0.42858 5.32787
144 2E1A MSE 0.01172 0.41676 5.33333
145 1RYI GOA 0.000000003148 0.5336 5.36913
146 1REO FAD 0.000002277 0.50674 5.36913
147 1RYI FAD 0.000003471 0.50319 5.36913
148 2JB2 FAD 0.000007409 0.4759 5.36913
149 3OND ADN 0.000001268 0.47049 5.36913
150 2JB2 PHE 0.000008125 0.46991 5.36913
151 3OND NAD 0.0005995 0.43009 5.36913
152 1V5F TPP 0.003722 0.41714 5.36913
153 1V5F FAD 0.003722 0.41714 5.36913
154 2NXE SAM 0.006499 0.42543 5.51181
155 4IXW IXW 0.01768 0.40895 5.51181
156 4K5S PM0 0.0000009002 0.53359 5.59284
157 4K5S FAD 0.0000001193 0.53119 5.59284
158 3GDN HBX 0.0001841 0.45163 5.59284
159 3GDN FAD 0.0001212 0.44969 5.59284
160 2IID PHE 0.000005969 0.42476 5.59284
161 2IID FAD 0.000005969 0.42476 5.59284
162 2QA1 FAD 0.00000001096 0.59433 5.6
163 5EVY FAD 0.004304 0.44935 5.70776
164 3GGO NAI 0.001164 0.41475 5.73248
165 4BJZ FAD 0.0000000001685 0.60357 5.89623
166 4BJZ P3A 0.0000002192 0.57752 5.89623
167 4EA7 JB2 0.001005 0.40397 5.90909
168 4EA7 COA 0.001005 0.40397 5.90909
169 1YJQ NAP 0.0009411 0.40173 5.94059
170 2YG3 FAD 0.0000006431 0.52761 6.04027
171 4HA6 FAD 0.00001605 0.4822 6.04027
172 3FPZ AHZ 0.000001438 0.49557 6.13497
173 4JNA FAD 0.00000001234 0.5917 6.17647
174 4NTD FAD 0.00000004388 0.56526 6.17647
175 4D04 NAP 0.00002149 0.4955 6.26398
176 1UWK URO 0.001379 0.41511 6.26398
177 3K7M FAD 0.0000009448 0.53773 6.2645
178 4PLG OXM 0.000002266 0.44968 6.28743
179 4PLG NAI 0.001294 0.40763 6.28743
180 4USQ FAD 0.000002769 0.49068 6.37119
181 1YKJ FAD 0.000002031 0.534 6.59898
182 3LST SAH 0.02652 0.40948 6.6092
183 2RGJ FAD 0.00000001846 0.55854 6.71642
184 3DGB MUC 0.004511 0.42553 6.80628
185 4COQ SAN 0.002032 0.46799 6.88259
186 2AE2 PTO 0.00004495 0.42067 6.92308
187 3PLN U5P 0.008018 0.42875 7.07547
188 2RHQ GAX 0.004382 0.40032 7.14286
189 3JV7 NAD 0.002278 0.41537 7.24638
190 1UXG FUM 0.0000008379 0.4623 7.44337
191 1UXG NAD 0.001017 0.41245 7.44337
192 1HSR BHO 0.03076 0.41248 7.55814
193 1G8S MET 0.000546 0.49524 7.82609
194 3OFK SAH 0.0006397 0.46001 7.87037
195 3AD8 NAD 0.000000006203 0.57779 8.05369
196 3UCL NAP 0.000003982 0.52765 8.05369
197 3UCL CYH 0.000003607 0.52654 8.05369
198 3AD8 FAD 0.00009308 0.47402 8.05369
199 3F81 STT 0.004255 0.47417 8.19672
200 2HJR APR 0.0001252 0.40218 8.23171
201 3H86 AP5 0.000376 0.40852 8.33333
202 3WGT QSC 0.000009468 0.49648 8.35735
203 3WGT FAD 0.000008791 0.49648 8.35735
204 1HKU NAD 0.002572 0.41081 8.37989
205 4II2 ATP 0.00002606 0.40926 8.43373
206 2VHW NAI 0.0006295 0.41454 8.48806
207 3ZNN 4WL 0.00001293 0.49902 8.64553
208 2IVD FAD 0.000004726 0.48932 8.94855
209 3WLE NAD 0.001515 0.4024 9.09091
210 1SOW NAD 0.0005473 0.40792 9.14634
211 2X3N FAD 0.0000001386 0.54603 9.27318
212 1DSS NAD 0.000154 0.40589 9.30931
213 4OPC PGT 0.0000006343 0.58174 9.39597
214 1W7J ADP BEF 0.003398 0.41811 9.39597
215 2DT5 NAD 0.000418 0.40159 9.47867
216 2NCD ADP 0.008162 0.43354 9.52381
217 1XDS SAM 0.01062 0.42586 10.4278
218 2F2U M77 0.01208 0.41192 10.4478
219 2C7G FAD 0.0000001288 0.57204 10.5145
220 2C7G ODP 0.0000003841 0.55331 10.5145
221 2PR5 FMN 0.003497 0.41391 10.6061
222 2NVK FAD 0.000000002762 0.61301 10.7383
223 1O94 ADP 0.0000000135 0.51811 10.962
224 1NAA ABL 0.000009692 0.50055 10.962
225 1NAA 6FA 0.000005189 0.49971 10.962
226 1DJN ADP 0.00000006147 0.49409 10.962
227 4CNK FAD 0.00000006179 0.56006 10.9974
228 1N9L FMN 0.003381 0.41445 11.0092
229 2GAG NAD 0.000000002038 0.60991 11.1111
230 2GAG FAD 0.00003668 0.47175 11.1111
231 2GAG FOA 0.00003773 0.47131 11.1111
232 2VDV SAM 0.003937 0.44718 12.1951
233 9LDB NAD 0.0002565 0.41549 12.3494
234 9LDT NAD 0.0002706 0.41481 12.3494
235 2XVF FAD 0.000003934 0.49538 12.528
236 3T31 DCQ 0.00000009741 0.57776 12.5858
237 3T31 FAD 0.00000008346 0.57776 12.5858
238 1LDN NAD 0.0008017 0.40036 12.6582
239 4G74 UQ5 0.000000001146 0.63711 12.7517
240 4G74 FAD 0.0000000002429 0.63711 12.7517
241 2XVE FAD 0.00002269 0.4928 12.7517
242 1ELI PYC 0.0001015 0.44748 12.9754
243 1PS9 FAD 0.000000003518 0.60928 13.1991
244 1V6A TRE 0.002936 0.4754 13.253
245 4J56 FAD 0.000000001038 0.63355 13.4228
246 1V7R CIT 0.02957 0.43588 13.4409
247 1LTH NAD 0.0001144 0.40732 13.4796
248 3AB1 FAD 0.00000001934 0.58133 13.6111
249 3SQP FAD 0.00000004142 0.65434 14.3177
250 4GUT FAD 0.00000008137 0.56865 14.5161
251 4GUS FAD 0.00000007051 0.5679 14.5161
252 4HSU FAD 0.000000264 0.54736 14.5161
253 2HMT NAI 0.000007791 0.43131 14.5833
254 1LVL FAD 0.000000002067 0.62108 17.4497
255 1LVL NAD 0.000001203 0.44142 17.4497
256 3LZW NAP 0.0000002956 0.56103 17.4699
257 3LZW FAD 0.00000007138 0.55786 17.4699
258 2HQM FAD 0.0000000007344 0.63528 17.6734
259 1E1M NAP 0.00000001879 0.60029 17.6734
260 1E6E FAD 0.00000002308 0.56879 17.6734
261 1FEC FAD 0.000000001592 0.63029 18.3445
262 2RAB NAD 0.00000000189 0.65167 18.5682
263 2RAB FAD 0.0000000004294 0.64728 18.5682
264 3QFA FAD 0.000000001311 0.62633 18.5682
265 2Q0L FAD 0.000000009173 0.59454 18.6495
266 3A2Y TS5 0.008539 0.40292 19.2893
267 1GET FAD 0.000000002568 0.64662 19.4631
268 1GET NAP 0.000000002965 0.64662 19.4631
269 1VDC FAD 0.0000001137 0.56484 19.8198
270 2CUL FAD 0.0000003579 0.52413 19.8276
271 1T26 GBD 0.00003869 0.46169 19.8758
272 1T26 NAI 0.002395 0.40359 19.8758
273 1JNR FAD 0.0000009187 0.55643 20
274 3VPH OXM 0.0005845 0.41499 20
275 1GV0 NAD 0.0004007 0.40583 20
276 3VPH NAD 0.001064 0.40055 20
277 1XHC FAD 0.000000000002001 0.70893 23.4332
278 3ITJ FAD 0.00000007997 0.57178 23.9645
279 4EMI NAD 0.000000000266 0.67717 24.3902
280 4EMI FAD 0.00000000005446 0.66699 24.3902
281 4EMJ FAD 0.0000000001592 0.65282 24.3902
282 3LAD FAD 0.0000000009339 0.63157 24.6085
283 3F8D FAD 0.0000001703 0.5817 24.7678
284 2A8X FAD 0.000000001039 0.63174 25
285 1TDF FAD 0.000000003641 0.61733 25.6329
286 1TDF NAP 0.00000003036 0.61032 25.6329
287 3CTY FAD 0.000000000111 0.66834 25.7053
288 2YVF FAD 0.000000001262 0.65189 25.9804
289 2YVF NAD 0.000000001369 0.65189 25.9804
290 2YVJ FAD 0.0000000001761 0.64697 25.9804
291 2YVJ NAI 0.000008251 0.41062 25.9804
292 3GD4 NAD 0.00000000257 0.65462 26.3982
293 3GD4 FAD 0.00000000171 0.64426 26.3982
294 1FL2 FAD 0.000000008775 0.59161 26.7742
295 2F5Z FAD 0.00000000009063 0.66957 27.0694
296 3RNM FAD 0.0000000001355 0.66334 27.0694
297 1ZMD FAD 0.00000000009128 0.60809 27.0694
298 1ZMD NAI 0.000003142 0.54507 27.0694
299 1LSS NAD 0.00001434 0.4185 27.1429
300 1Q1R FAD 0.00000000002657 0.6756 27.1462
301 2V6O FAD 0.000000004833 0.45285 27.5168
302 4M52 FAD 0.0000000006011 0.63838 30.2575
303 2V3A FAD 0.0000000005555 0.63169 31.25
304 2V3B FAD 0.0000000005626 0.62939 31.25
305 1V59 FAD 0.000000000367 0.65153 31.59
306 1V59 NAD 0.0000002295 0.42085 31.59
307 2Q7V FAD 0.000000001857 0.61911 31.6923
308 1BZL FAD 0.00000002741 0.63038 33.3333
309 2WPF WPF 0.000000006898 0.65584 33.7808
310 2WPF FAD 0.000000006122 0.65536 33.7808
311 4JDR FAD 0.0000000003686 0.644 34.2282
312 3FG2 FAD 0.00000000006853 0.63863 34.4059
313 3LXD FAD 0.00000000005315 0.6542 34.9398
314 1ZK7 FAD 0.0000000001379 0.66682 35.123
315 1MO9 KPC 0.000000006524 0.64416 35.123
316 1MO9 FAD 0.00000001673 0.6273 35.123
317 3KLJ FAD 0.000000000134 0.63109 36.6234
318 3NT6 FAD 0.0000000000004354 0.74041 46.7562
319 3NTA FAD 0.0000000000004425 0.74016 46.7562
320 1YQZ FAD 0.00000000001861 0.71883 47.4886
321 3NTD FAD 0.0000000000005612 0.73655 48.3221
322 3CGB FAD 0.000000000008767 0.69239 48.9933
323 3ICS FAD 0.0000000000009416 0.72869 49.217
324 3ICR FAD 0.000000000001315 0.72111 49.217
325 3ICT FAD 0.000000000001498 0.71914 49.217
326 3ICT ADP 0.0000009475 0.41015 49.217
327 3ICS ADP 0.000003685 0.4011 49.217
Pocket No.: 2; Query (leader) PDB : 2NPX; Ligand: NAD; Similar sites found: 270
This union binding pocket(no: 2) in the query (biounit: 2npx.bio2) has 58 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1TB4 PEJ 0.01224 0.40265 1.07817
2 4Q0A GLY HIS LYS ILE LEU HIS ARG LEU LEU GLN 0.0162 0.40463 1.3245
3 2BRY FAD 0.0000001504 0.4406 1.34228
4 3WE0 FAD 0.0000142 0.42281 1.34228
5 2O4J VD4 0.004034 0.40677 1.36986
6 1Z44 NPO 0.02843 0.45952 1.47929
7 1Z44 FMN 0.01406 0.41705 1.47929
8 1PN0 FAD 0.0000004801 0.47056 1.566
9 1PN0 IPH 0.0000006474 0.46947 1.566
10 1M2W NAD 0.01319 0.41535 1.566
11 4MO2 FDA 0.000004828 0.51592 1.63043
12 4MO2 FAD 0.000006422 0.50795 1.63043
13 1VKO NAD 0.00431 0.41669 2.01342
14 1N4W FAD 0.00003557 0.41014 2.01342
15 4DMG SAM 0.00333 0.47218 2.03562
16 3SJU NDP 0.01158 0.40153 2.15054
17 2Q37 3AL 0.003147 0.46978 2.20994
18 1E6W NAD 0.006369 0.41437 2.30769
19 3SHR CMP 0.004831 0.44541 2.34114
20 1SJD NPG 0.007109 0.40368 2.44565
21 2Z3Y F2N 0.0000005111 0.46145 2.46085
22 2WET FAD 0.000004163 0.43351 2.46085
23 4E28 9MZ 0.03359 0.42415 2.46154
24 4DPL NAP 0.00507 0.41845 2.50696
25 1SS4 GSH 0.0002951 0.59235 2.61438
26 1SS4 CIT 0.00523 0.51102 2.61438
27 3NYC FAD 0.00005093 0.42176 2.62467
28 1GTE FAD 0.000000003585 0.55694 2.68456
29 2WA4 069 0.02014 0.41393 2.86533
30 4EIP K2C 0.000001802 0.45385 2.90828
31 4EIP FAD 0.000002281 0.44556 2.90828
32 1U8X NAD 0.009772 0.41359 2.90828
33 1TV5 ORO 0.009145 0.41951 2.93454
34 3G2O SAM 0.004579 0.44919 3.01003
35 2GJN NIS 0.003988 0.40429 3.04878
36 2B9W FAD 0.00001314 0.4459 3.06604
37 1PEA ACM 0.006693 0.47248 3.11688
38 2IXB NAD 0.005626 0.41429 3.15315
39 2IXB A2G 0.005102 0.40151 3.15315
40 3QJ4 FAD 0.00000102 0.53727 3.21637
41 3MAG SAH 0.01193 0.40681 3.25733
42 3OZ2 FAD 0.00000001554 0.49074 3.27456
43 3GDH SAH 0.004804 0.4324 3.3195
44 1Q9I FAD 0.000001111 0.48375 3.3275
45 4TM3 FAD 0.000000008805 0.55371 3.386
46 3G5S FAD 0.00000003795 0.46974 3.386
47 3S9K CIT 0.004725 0.50644 3.38983
48 1KNR FAD 0.0000007857 0.4473 3.57942
49 1Z82 NDP 0.01611 0.40195 3.58209
50 1HDG NAD 0.001279 0.45483 3.61446
51 1CER NAD 0.000103 0.4989 3.62538
52 1D4D FAD 0.0000001823 0.47038 3.67133
53 3DMH SAM 0.008416 0.43 3.67454
54 3DMH GMP 0.01583 0.40227 3.67454
55 1MXI SAH 0.002745 0.435 3.75
56 2GN4 NDP 0.000689 0.40915 3.77907
57 2R4J FAD 0.0001087 0.41471 3.79242
58 4B63 NAP 0.000000000009607 0.59145 3.80313
59 4B63 FAD 0.00000000001457 0.58555 3.80313
60 4B63 ORN 0.00000000001457 0.58555 3.80313
61 3UOY NAP 0.0000009698 0.49111 3.80313
62 3S5W FAD 0.0000004573 0.42449 3.80313
63 1COY FAD 0.00003601 0.40586 3.80313
64 4NTC FAD 0.00000002134 0.4903 3.8806
65 2Y6Q I7T 0.000005109 0.44194 4.0201
66 2Y6Q FAD 0.000001364 0.41776 4.0201
67 4AP3 NAP 0.00007634 0.42905 4.02685
68 4AT0 FAD 0.00006125 0.41311 4.02685
69 4C3Y FAD 0.00000964 0.42186 4.15094
70 4C3Y ANB 0.00002835 0.42091 4.15094
71 1DLJ NAI 0.00007581 0.41348 4.22886
72 1DLJ UGA 0.0001352 0.40639 4.22886
73 3AXB PRO 0.000009112 0.42509 4.24107
74 3AXB FAD 0.000005384 0.41742 4.24107
75 2ZXI FAD 0.000000006159 0.48797 4.25056
76 1QO8 FAD 0.0000001313 0.47157 4.25056
77 1H82 GZZ 0.000007722 0.45941 4.25056
78 2E5V FAD 0.0000008381 0.45358 4.25056
79 1H82 FAD 0.000009213 0.45244 4.25056
80 2VVL FAD 0.000002912 0.43622 4.25056
81 4IV9 FAD 0.000002828 0.43281 4.25056
82 2VVM FAD 0.000003068 0.432 4.25056
83 4MIG G3F 0.00001774 0.43084 4.25056
84 2AQJ FAD 0.0001381 0.42059 4.25056
85 2AQJ TRP 0.0001476 0.41887 4.25056
86 1Y42 TYR 0.02101 0.42504 4.33673
87 1I8T FAD 0.000005423 0.42293 4.35967
88 5TUF FAD 0.00069 0.48029 4.40098
89 5TUF TDC 0.003834 0.40486 4.40098
90 2GMH FAD 0.0000002486 0.54814 4.47427
91 3NKS FAD 0.00000961 0.5048 4.47427
92 3E1T FAD 0.00000004477 0.48802 4.47427
93 4FWE FAD 0.0000004438 0.46108 4.47427
94 1VQW FAD 0.00000157 0.41775 4.47427
95 2GVC FAD 0.000001627 0.41727 4.47427
96 2GV8 FAD 0.000002573 0.41642 4.47427
97 1BW9 NAD 0.0001468 0.50817 4.49438
98 1C1X NAD 0.0001367 0.4936 4.50704
99 3TLJ SAH 0.01909 0.40802 4.55764
100 3GF4 UPG 0.00001684 0.44654 4.61538
101 3GF4 FAD 0.00002152 0.43804 4.61538
102 2AHR NAP 0.0005513 0.42654 4.6332
103 3AYI HCI 0.000004498 0.45592 4.69799
104 3AYI FAD 0.000004344 0.45438 4.69799
105 2DKH FAD 0.0000001355 0.44196 4.69799
106 2DKH 3HB 0.000001688 0.43432 4.69799
107 2RGO FAD 0.00001541 0.4079 4.69799
108 2F6U CIT 0.03696 0.42763 4.70085
109 3GMB FAD 0.0000001396 0.44623 4.81928
110 3GFB NAD 0.0009282 0.45466 4.85714
111 3IHG FAD 0.00000001962 0.44354 4.9217
112 1RP0 AHZ 0.0000007102 0.41854 4.92958
113 2JJQ SAH 0.0032 0.46868 4.94118
114 3HDY FAD 0.000007036 0.46061 5.03778
115 3HDY FDA 0.000008833 0.45768 5.03778
116 3HDY GDU 0.000009535 0.45763 5.03778
117 4J36 1HR 0.000001088 0.45128 5.06024
118 4J36 FAD 0.0000002043 0.43968 5.06024
119 1JQ3 AAT 0.005301 0.41091 5.06757
120 1YY5 FAD 0.0000002468 0.47126 5.14541
121 4DSG FAD 0.000004309 0.46789 5.14541
122 4DSG UDP 0.000008161 0.45774 5.14541
123 1RSG FAD 0.000001091 0.44897 5.14541
124 5TS5 FAD 0.006228 0.42101 5.14541
125 4USR FAD 0.000005042 0.40796 5.26316
126 2E1A MSE 0.00832 0.43934 5.33333
127 2JB2 FAD 0.00001375 0.4927 5.36913
128 2JB2 PHE 0.0000155 0.48781 5.36913
129 1RYI GOA 0.0000000247 0.4396 5.36913
130 1REO FAD 0.000005525 0.42387 5.36913
131 1RYI FAD 0.00001829 0.41675 5.36913
132 2ZO9 MLI 0.01655 0.41955 5.47445
133 2NXE SAM 0.01402 0.42543 5.51181
134 4IXW IXW 0.04065 0.40749 5.51181
135 2IID PHE 0.00002784 0.44647 5.59284
136 2IID FAD 0.00002784 0.44647 5.59284
137 4K5S PM0 0.000008525 0.43857 5.59284
138 4K5S FAD 0.0000003655 0.43392 5.59284
139 2QA1 FAD 0.00000004276 0.60154 5.6
140 5EVY FAD 0.003452 0.47083 5.70776
141 4BJZ FAD 0.000000003746 0.48695 5.89623
142 4BJZ P3A 0.000005712 0.47054 5.89623
143 4EA7 COA 0.000004159 0.41726 5.90909
144 3BAZ NAP 0.0005632 0.47043 6.00601
145 2YG3 FAD 0.000003273 0.43126 6.04027
146 4HA6 FAD 0.00009552 0.40141 6.04027
147 4JNA FAD 0.00000012 0.47462 6.17647
148 4NTD FAD 0.0000002203 0.45444 6.17647
149 4D04 NAP 0.000001959 0.47808 6.26398
150 3K7M FAD 0.000006033 0.45184 6.2645
151 4USQ FAD 0.000008424 0.40676 6.37119
152 2B5W NAP 0.002057 0.42248 6.44258
153 1YKJ FAD 0.00001387 0.4528 6.59898
154 3OA2 NAD 0.001895 0.43873 6.60377
155 2RGJ FAD 0.00000009797 0.4473 6.71642
156 3DGB MUC 0.007427 0.43282 6.80628
157 4COQ SAN 0.0295 0.42702 6.88259
158 1E3I CXF 0.0002856 0.45262 6.91489
159 3PLN U5P 0.01491 0.43212 7.07547
160 2RHQ GAX 0.01181 0.40121 7.14286
161 3JV7 NAD 0.0004525 0.46165 7.24638
162 2QLX RM4 0.01588 0.44618 7.40741
163 1SJW NGV 0.01007 0.41955 7.63889
164 1G8S MET 0.001299 0.49524 7.82609
165 3OFK SAH 0.001627 0.46001 7.87037
166 3UCL NAP 0.0000009057 0.49296 8.05369
167 3UCL CYH 0.000001075 0.48783 8.05369
168 3AD8 NAD 0.00000002767 0.45959 8.05369
169 3AD8 FAD 0.0005991 0.40637 8.05369
170 3F81 STT 0.008497 0.47417 8.19672
171 3WGT FAD 0.0000295 0.42334 8.35735
172 3WGT QSC 0.00003957 0.42195 8.35735
173 1HKU NAD 0.0002132 0.47193 8.37989
174 3ZNN 4WL 0.00003371 0.43603 8.64553
175 2IVD FAD 0.000006952 0.41473 8.94855
176 2X3N FAD 0.0000004622 0.44405 9.27318
177 4OPC PGT 0.000009456 0.48342 9.39597
178 2NCD ADP 0.005042 0.45983 9.52381
179 1XDS SAM 0.02139 0.42586 10.4278
180 2F2U M77 0.01278 0.42654 10.4478
181 2C7G FAD 0.000000002829 0.55298 10.5145
182 2C7G ODP 0.000000005753 0.5418 10.5145
183 2NVK FAD 0.00000002281 0.49031 10.7383
184 1NAA ABL 0.00007196 0.42073 10.962
185 1O94 ADP 0.00000006239 0.4167 10.962
186 1NAA 6FA 0.00003662 0.40957 10.962
187 1DJN ADP 0.000000256 0.40092 10.962
188 4CNK FAD 0.0000002908 0.45123 10.9974
189 1N9L FMN 0.007416 0.41802 11.0092
190 2GAG NAD 0.000000007942 0.48658 11.1111
191 2VDV SAM 0.008324 0.44718 12.1951
192 2XVF FAD 0.000009723 0.41121 12.528
193 3T31 DCQ 0.000002473 0.46914 12.5858
194 3T31 FAD 0.000001826 0.46914 12.5858
195 4G74 UQ5 0.00000001816 0.51102 12.7517
196 4G74 FAD 0.000000001898 0.50122 12.7517
197 2XVE FAD 0.000006459 0.46074 12.7517
198 1PS9 FAD 0.00000004201 0.48384 13.1991
199 1V6A TRE 0.005794 0.4754 13.253
200 4J56 FAD 0.0000000113 0.50732 13.4228
201 1V7R CIT 0.02833 0.45176 13.4409
202 3AB1 FAD 0.0000001532 0.4644 13.6111
203 3SQP FAD 0.0000000007729 0.64415 14.3177
204 4GUT FAD 0.0000004471 0.46992 14.5161
205 4GUS FAD 0.0000003747 0.46634 14.5161
206 4HSU FAD 0.000001016 0.45503 14.5161
207 2VOH CIT 0.01435 0.46871 15.3846
208 1LVL FAD 0.00000001482 0.50076 17.4497
209 3LZW FAD 0.0000003385 0.45062 17.4699
210 3LZW NAP 0.00001967 0.44457 17.4699
211 1E1M NAP 0.000000001784 0.55365 17.6734
212 2HQM FAD 0.000000006179 0.50859 17.6734
213 1E6E FAD 0.000000111 0.45605 17.6734
214 1FEC FAD 0.00000001981 0.50676 18.3445
215 2RAB NAD 0.000000000001689 0.66301 18.5682
216 2RAB FAD 0.000000006151 0.51279 18.5682
217 3QFA FAD 0.00000001311 0.50072 18.5682
218 2Q0L FAD 0.00000005941 0.48009 18.6495
219 1GET NAP 0.000000000003348 0.65697 19.4631
220 1GET FAD 0.000000000005993 0.6465 19.4631
221 1VDC FAD 0.000001406 0.45901 19.8198
222 2CUL FAD 0.0000008639 0.43348 19.8276
223 1JNR FAD 0.000006529 0.47126 20
224 1XHC FAD 0.00000000001039 0.55802 23.4332
225 3ITJ FAD 0.000001158 0.46401 23.9645
226 4EMI NAD 0.0000000000002004 0.68259 24.3902
227 4EMI FAD 0.0000000003053 0.52881 24.3902
228 4EMJ FAD 0.000000000955 0.52007 24.3902
229 3LAD FAD 0.000000005543 0.5074 24.6085
230 3F8D FAD 0.0000002322 0.51277 24.7678
231 2A8X FAD 0.000000008061 0.50752 25
232 1TDF NAP 0.0000002847 0.51009 25.6329
233 1TDF FAD 0.00000006783 0.492 25.6329
234 3CTY FAD 0.00000000171 0.52843 25.7053
235 2YVF NAD 0.0000000000001795 0.68571 25.9804
236 2YVF FAD 0.000000000000165 0.68509 25.9804
237 2YVJ FAD 0.0000000006732 0.51702 25.9804
238 3GD4 NAD 0.00000000002738 0.63588 26.3982
239 3GD4 FAD 0.0000000291 0.52762 26.3982
240 1FL2 FAD 0.00000006615 0.47231 26.7742
241 1ZMD NAI 0.0000000199 0.66543 27.0694
242 1ZMD FAD 0.0000000009005 0.62471 27.0694
243 2F5Z FAD 0.0000000008688 0.53099 27.0694
244 3RNM FAD 0.000000001201 0.52716 27.0694
245 1Q1R FAD 0.0000000001466 0.53326 27.1462
246 2V6O FAD 0.000000000107 0.5464 27.5168
247 4M52 FAD 0.000000003957 0.51156 30.2575
248 2V3A FAD 0.000000002985 0.50695 31.25
249 2V3B FAD 0.000000002353 0.50543 31.25
250 1V59 FAD 0.000000004481 0.51938 31.59
251 2Q7V FAD 0.0000000196 0.49138 31.6923
252 1BZL FAD 0.000000957 0.51017 33.3333
253 3KPE TM3 0.01638 0.43995 33.3333
254 2WPF WPF 0.0000000001278 0.63547 33.7808
255 2WPF FAD 0.0000000001165 0.63388 33.7808
256 4JDR FAD 0.000000002263 0.51372 34.2282
257 3FG2 FAD 0.0000000004277 0.50218 34.4059
258 3LXD FAD 0.0000000002279 0.51891 34.9398
259 1MO9 KPC 0.00000000001559 0.64949 35.123
260 1MO9 FAD 0.00000000003781 0.6364 35.123
261 1ZK7 FAD 0.000000002419 0.52723 35.123
262 3KLJ FAD 0.0000000009825 0.49878 36.6234
263 3NT6 FAD 0.000000000005664 0.56903 46.7562
264 3NTA FAD 0.000000000005766 0.568 46.7562
265 1YQZ FAD 0.00000000332 0.55662 47.4886
266 3NTD FAD 0.000000000006835 0.56643 48.3221
267 3CGB FAD 0.00000000007215 0.54262 48.9933
268 3ICS FAD 0.00000000001371 0.56023 49.217
269 3ICR FAD 0.00000000001243 0.55658 49.217
270 3ICT FAD 0.0000000000142 0.55498 49.217
Pocket No.: 3; Query (leader) PDB : 2NPX; Ligand: FAD; Similar sites found: 91
This union binding pocket(no: 3) in the query (biounit: 2npx.bio1) has 39 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5MBX FAD 0.0000008202 0.54116 1.34228
2 5MBX SP5 0.0000008202 0.54116 1.34228
3 1J0X NAD 0.001065 0.41715 1.80723
4 4D7E FAD 0.00003122 0.46107 1.8648
5 4TXI FAD 0.00000006092 0.53531 2.01342
6 4YCA NDP 0.0002137 0.46543 2.04082
7 5O4J SAH 0.0007578 0.40897 2.55474
8 5O4J 9KH 0.0007578 0.40897 2.55474
9 5O4J PJL 0.001139 0.40051 2.55474
10 3NYC IAR 0.000006863 0.50385 2.62467
11 4U8P UDP 0.000004862 0.52523 2.68456
12 4U8P FDA 0.000004368 0.52523 2.68456
13 5J7X FAD 0.000004169 0.49602 2.90828
14 5N53 8NB 0.003112 0.47412 3.07692
15 5HSA FAS 0.00002328 0.4739 3.13199
16 4Z24 FAD 0.00003907 0.46719 3.13199
17 4ZCC NAI 0.0000007154 0.53974 3.27381
18 4ZCC FAD 0.0000007154 0.53974 3.27381
19 1Q9I TEO 0.00000006626 0.58397 3.3275
20 4YNU FAD 0.00004293 0.46813 3.3557
21 4YNU LGC 0.00006526 0.46603 3.3557
22 1GPE FAD 0.00006079 0.46386 3.3557
23 5BVA FAD 0.000000003403 0.61507 3.42298
24 4REP FAD 0.0000002822 0.53862 3.43434
25 1OC2 TDX 0.005718 0.40012 3.44828
26 5M67 NAD 0.0007937 0.42661 3.75783
27 5M67 ADE 0.0007943 0.4266 3.75783
28 5M67 3D1 0.0008137 0.42622 3.75783
29 2R4J 13P 0.00001476 0.49277 3.79242
30 3UOY FAD 0.00001232 0.50813 3.80313
31 5EZ7 FAD 0.00001457 0.47841 3.82653
32 5TTJ FAD 0.000001061 0.51841 3.87755
33 4MOP 2H5 0.000001986 0.52471 4.02685
34 4AP3 FAD 0.000008672 0.50842 4.02685
35 5MZI FAD 0.000000252 0.56476 4.25056
36 5MZI FYK 0.00000027 0.56476 4.25056
37 3FPF TNA 0.001827 0.40463 4.36242
38 5FJN BE2 0.0000003012 0.54674 4.38596
39 5FJN FAD 0.0000003403 0.54046 4.38596
40 5TUF TDC 0.0000003946 0.44016 4.40098
41 4RSL FAD 0.0000295 0.462 4.49438
42 4X9M FAD 0.000001752 0.51225 4.54545
43 5BUK FAD 0.000000007238 0.60333 4.69799
44 5UAO FAD 0.00000327 0.49972 4.69799
45 5G3U FDA 0.000006544 0.48917 4.72813
46 5G3U ITW 0.00005216 0.4651 4.72813
47 5I39 FAD 0.0000009357 0.51874 4.90196
48 5WGR FAD 0.0000007482 0.52529 4.9217
49 4RPL FAD 0.000001598 0.53891 5.01253
50 4RPL 3UC 0.000002019 0.53795 5.01253
51 3NJ4 NAD 0.00475 0.42927 5.51724
52 3NJ4 AFX 0.01168 0.41332 5.51724
53 5BR7 FLC 0.00000269 0.52843 5.59796
54 5BR7 FAD 0.000002892 0.52725 5.59796
55 5EOW FAD 0.00000001741 0.56389 5.67901
56 3GGO ENO 0.001164 0.41475 5.73248
57 4D04 FAD 0.00002149 0.4955 6.26398
58 1UWK NAD 0.001379 0.41511 6.26398
59 5JE8 NAD 0.0005897 0.45079 6.29139
60 4YSX FAD 0.0000004295 0.5338 6.38298
61 1YKJ PHB 0.000002031 0.534 6.59898
62 3UCL FAD 0.000003607 0.52654 8.05369
63 3AD8 PYC 0.00009308 0.47402 8.05369
64 2ZJ1 ARJ 0.002548 0.40991 8.05369
65 2ZJ1 NAD 0.002775 0.40855 8.05369
66 4XQC 13D 0.002331 0.40596 8.50112
67 4XQC NAD 0.003132 0.40041 8.50112
68 3ZNN FAD 0.00001293 0.49902 8.64553
69 4OPC FDA 0.0000004804 0.58174 9.39597
70 5TUK FAD 0.0000003749 0.48921 9.55882
71 5EB4 FAD 0.00006814 0.45613 10.0671
72 4ZVV NAD 0.003166 0.41187 12.3494
73 4ZVV GN0 0.003166 0.41187 12.3494
74 4YUW 4JU 0.0149 0.40472 12.8289
75 4YUW S4M 0.01455 0.40472 12.8289
76 1E1M FAD 0.00000001879 0.60029 17.6734
77 5ODQ FAD 0.0000000878 0.56139 20.1342
78 5JCA FAD 0.000000004177 0.60843 21.0291
79 5JCA NDP 0.00000001976 0.60843 21.0291
80 5U8U FAD 0.0000000002242 0.68541 21.2528
81 4UP3 FAD 0.00000000734 0.59617 23.8854
82 5J60 FAD 0.000000004718 0.60295 24.6875
83 5JCM NAD 0.000000005119 0.6341 25.0559
84 5JCM FAD 0.000000004755 0.6341 25.0559
85 5JCM ISD 0.000000005119 0.6341 25.0559
86 4BV6 FAD 0.0000000001151 0.66191 26.3982
87 5JWC FAD 0.00000000003343 0.66112 29.5302
88 4YRY FAD 0.000000004195 0.60836 30.6488
89 4YRY NAD 0.00000002054 0.59887 30.6488
90 5KMS FAD 0.000000001121 0.61448 33.5802
91 5KMS NAD 0.000000024 0.60159 33.5802
Pocket No.: 4; Query (leader) PDB : 2NPX; Ligand: NAD; Similar sites found: 63
This union binding pocket(no: 4) in the query (biounit: 2npx.bio1) has 58 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5MBX SP5 0.000004825 0.45671 1.34228
2 5MBX FAD 0.000004825 0.45671 1.34228
3 4TXI FAD 0.0000002425 0.43153 2.01342
4 4YCA NDP 0.0000621 0.50837 2.04082
5 4XYB NDP 0.004205 0.41271 2.04604
6 3NYC IAR 0.00005093 0.42176 2.62467
7 4U8P UDP 0.00002628 0.44961 2.68456
8 4U8P FDA 0.00002356 0.4494 2.68456
9 5J7X FAD 0.00001132 0.41092 2.90828
10 4X60 SFG 0.003407 0.40602 2.90828
11 4X60 3XV 0.004193 0.40089 2.90828
12 5N53 8NB 0.002378 0.49875 3.07692
13 4ZCC NAI 0.000008167 0.44375 3.27381
14 4ZCC FAD 0.000008167 0.44375 3.27381
15 1Q9I TEO 0.000001111 0.4791 3.3275
16 5BVA FAD 0.00000003231 0.49502 3.42298
17 4REP FAD 0.000001415 0.4376 3.43434
18 2R4J 13P 0.0001087 0.41471 3.79242
19 3UOY FAD 0.0000009698 0.49111 3.80313
20 5TTJ FAD 0.000004153 0.42527 3.87755
21 4MOP 2H5 0.00001017 0.44351 4.02685
22 4AP3 FAD 0.00007634 0.42905 4.02685
23 5MZI FYK 0.000002202 0.47456 4.25056
24 5MZI FAD 0.00000218 0.47365 4.25056
25 5FJN BE2 0.000001927 0.45077 4.38596
26 5FJN FAD 0.000001894 0.44273 4.38596
27 4X9M FAD 0.000006296 0.42576 4.54545
28 5BUK FAD 0.0000000223 0.49929 4.69799
29 5UAO FAD 0.000005926 0.42078 4.69799
30 5G3U FDA 0.00001745 0.40953 4.72813
31 5G3U ITW 0.00007708 0.4061 4.72813
32 5I39 FAD 0.000003727 0.42378 4.90196
33 5WGR FAD 0.000002557 0.43429 4.9217
34 4RPL FAD 0.000005477 0.46574 5.01253
35 4RPL 3UC 0.000009408 0.4614 5.01253
36 5BR7 FLC 0.00001786 0.44862 5.59796
37 5BR7 FAD 0.00002216 0.44584 5.59796
38 5EOW FAD 0.00000006054 0.45594 5.67901
39 4D04 FAD 0.000001959 0.47808 6.26398
40 5JE8 NAD 0.0002088 0.48931 6.29139
41 4YSX FAD 0.000001268 0.4424 6.38298
42 1YKJ PHB 0.00001387 0.4528 6.59898
43 3UCL FAD 0.000001075 0.48783 8.05369
44 3AD8 PYC 0.0005991 0.40637 8.05369
45 3ZNN FAD 0.00003371 0.43603 8.64553
46 4OPC FDA 0.000009477 0.4791 9.39597
47 5TUK FAD 0.000001254 0.40051 9.55882
48 1E1M FAD 0.000000001784 0.55365 17.6734
49 5ODQ FAD 0.0000003065 0.46502 20.1342
50 5JCA NDP 0.000000001648 0.56823 21.0291
51 5JCA FAD 0.00000002424 0.49161 21.0291
52 5U8U FAD 0.00000000000003619 0.71146 21.2528
53 4UP3 FAD 0.00000003806 0.4818 23.8854
54 5J60 FAD 0.0000000367 0.48193 24.6875
55 5JCM NAD 0.00000000001084 0.63734 25.0559
56 5JCM ISD 0.00000000002189 0.62821 25.0559
57 5JCM FAD 0.00000000001961 0.62821 25.0559
58 4BV6 FAD 0.000000001022 0.52683 26.3982
59 5JWC FAD 0.0000000002946 0.51515 29.5302
60 4YRY NAD 0.000000008375 0.5341 30.6488
61 4YRY FAD 0.00000003147 0.48872 30.6488
62 5KMS NAD 0.000000000004971 0.63819 33.5802
63 5KMS FAD 0.000000004917 0.49384 33.5802
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