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Receptor
PDB id Resolution Class Description Source Keywords
2NU5 1.56 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF A COMPLEX OF GRIFFITHSIN COCRYSTALLIZED ACETYLGLUCOSAMINE GRIFFITHSIA SP. GRIFFITHSIN; LECTINS; DOMAIN SWAPPING; MANNOSE BINDING; HIV;ANTIVIRAL PROTEIN SUGAR BINDING PROTEIN
Ref.: CRYSTALLOGRAPHIC STUDIES OF THE COMPLEXES OF ANTIVI PROTEIN GRIFFITHSIN WITH GLUCOSE AND N-ACETYLGLUCOS PROTEIN SCI. V. 16 1485 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG A:122;
A:123;
A:124;
B:122;
B:123;
B:124;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
submit data
221.208 C8 H15 N O6 CC(=O...
SO4 A:9001;
B:9002;
B:9003;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2NU5 1.56 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF A COMPLEX OF GRIFFITHSIN COCRYSTALLIZED ACETYLGLUCOSAMINE GRIFFITHSIA SP. GRIFFITHSIN; LECTINS; DOMAIN SWAPPING; MANNOSE BINDING; HIV;ANTIVIRAL PROTEIN SUGAR BINDING PROTEIN
Ref.: CRYSTALLOGRAPHIC STUDIES OF THE COMPLEXES OF ANTIVI PROTEIN GRIFFITHSIN WITH GLUCOSE AND N-ACETYLGLUCOS PROTEIN SCI. V. 16 1485 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2NU5 - NAG C8 H15 N O6 CC(=O)N[C@....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2NU5 - NAG C8 H15 N O6 CC(=O)N[C@....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2NU5 - NAG C8 H15 N O6 CC(=O)N[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAG; Similar ligands found: 105
No: Ligand ECFP6 Tc MDL keys Tc
1 NGA 1 1
2 NAG 1 1
3 A2G 1 1
4 BM3 1 1
5 HSQ 1 1
6 NDG 1 1
7 BGN 0.638298 0.888889
8 SIZ 0.630435 0.906977
9 YX1 0.625 0.65
10 STZ 0.612245 0.65
11 4QY 0.591837 0.735849
12 BMX 0.591837 0.735849
13 16G 0.591837 0.735849
14 9C1 0.58 0.886364
15 SNG 0.5625 0.866667
16 NGS 0.54902 0.661017
17 NDG NAG 0.54386 0.833333
18 CBS 0.54386 0.833333
19 NAG GDL 0.54386 0.833333
20 CBS CBS 0.54386 0.833333
21 ASG 0.538462 0.661017
22 BG8 0.537037 0.906977
23 MAG 0.530612 0.909091
24 2F8 0.530612 0.909091
25 NDG GAL 0.517857 0.888889
26 NLC 0.517857 0.888889
27 GAL NDG 0.517857 0.888889
28 NAG A2G 0.517241 0.833333
29 4V5 0.517241 0.829787
30 NAG NGA 0.517241 0.833333
31 4UZ 0.508475 0.808511
32 NAG NAG NAG NAG NDG 0.508197 0.816327
33 NDG NAG NAG NAG 0.508197 0.816327
34 NAG NAG NDG 0.508197 0.816327
35 NAG NAG NDG NAG 0.508197 0.816327
36 CTO 0.508197 0.816327
37 NDG NAG NAG NDG 0.508197 0.816327
38 NAG NAG NAG NDG 0.508197 0.816327
39 NDG NAG NAG 0.508197 0.816327
40 NAG NAG NAG NAG NAG 0.508197 0.816327
41 NAG NAG NAG NAG NAG NAG 0.508197 0.816327
42 NAG NAG NAG NAG NAG NAG NAG NAG 0.508197 0.816327
43 MQG 0.5 0.698113
44 NBG 0.5 0.951219
45 GAL NGA 0.491228 0.888889
46 A2G GAL 0.491228 0.888889
47 GAL A2G 0.491228 0.888889
48 AMU 0.490909 0.930233
49 NG1 0.490566 0.754717
50 GN1 0.490566 0.754717
51 NAG GAL 0.474576 0.888889
52 GAL NAG 0.474576 0.888889
53 NAG FUC 0.474576 0.866667
54 NAG GAL NAG 0.455882 0.833333
55 3YW 0.448276 0.930233
56 GLA GAL NAG 0.446154 0.888889
57 MAN BMA NAG 0.446154 0.888889
58 NGA GAL 0.428571 0.869565
59 FUC GAL NAG 0.426471 0.869565
60 GAL NAG FUC 0.426471 0.869565
61 DR2 0.426471 0.869565
62 NAG GAL FUC 0.426471 0.869565
63 NDG GAL FUC 0.426471 0.869565
64 FUC GAL NDG 0.426471 0.869565
65 FUL GAL NAG 0.426471 0.869565
66 G6S NAG 0.426471 0.645161
67 TNR 0.42623 0.833333
68 GYU 0.42623 0.740741
69 GAL NGA A2G 0.424242 0.833333
70 NAG BDP 0.421875 0.851064
71 NAG MBG 0.419355 0.851064
72 NGA GAL BGC 0.41791 0.888889
73 NAG NDG 0.415385 0.784314
74 NAG NAG 0.415385 0.784314
75 AZC 0.415094 0.795918
76 SN5 SN5 0.412698 0.705882
77 A2G MBG 0.412698 0.851064
78 MBG A2G 0.412698 0.851064
79 HS2 0.411765 0.8125
80 5AX 0.411765 0.866667
81 NAG MAN BMA 0.411765 0.888889
82 6ZC 0.409091 0.655738
83 LEC 0.409091 0.655738
84 TCG 0.408451 0.689655
85 GAL BGC NAG GAL 0.408451 0.888889
86 NAG MAN 0.40625 0.851064
87 WOO 0.404762 0.7
88 MAN 0.404762 0.7
89 GAL 0.404762 0.7
90 BGC 0.404762 0.7
91 BMA 0.404762 0.7
92 GLA 0.404762 0.7
93 ALL 0.404762 0.7
94 GLC 0.404762 0.7
95 GXL 0.404762 0.7
96 GIV 0.404762 0.7
97 NAG AMU 0.402778 0.8
98 NAG MUB 0.402778 0.8
99 NAG A2G GAL 0.402778 0.833333
100 A2G GAL FUC 0.4 0.869565
101 FUC GLA A2G 0.4 0.869565
102 DR3 0.4 0.869565
103 A2G GLA FUC 0.4 0.869565
104 NGA GAL FUC 0.4 0.869565
105 FUC GAL A2G 0.4 0.869565
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2NU5; Ligand: NAG; Similar sites found with APoc: 284
This union binding pocket(no: 1) in the query (biounit: 2nu5.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2BQP GLC None
2 1OFS SUC None
3 1LES GLC FRU None
4 1WPY BTN None
5 2DXU BT5 None
6 2O07 MTA None
7 2HMT NAI None
8 1N2X SAM None
9 4KCT PYR 1.63934
10 5C5H 4YB 1.63934
11 2JE7 XMM 2.45902
12 1HYH NAD 2.45902
13 5N81 8Q2 2.45902
14 5X9D 80F 3.27869
15 5BVA FAD 3.27869
16 1PZG A3D 3.27869
17 1DJN ADP 3.27869
18 3OU2 SAH 3.27869
19 4MO2 FDA 4.09836
20 4MO2 FAD 4.09836
21 1SOW NAD 4.09836
22 5BUK FAD 4.09836
23 2DKH FAD 4.09836
24 5ZYN FAD 4.09836
25 1VFS DCS 4.09836
26 6AM8 TRP 4.09836
27 16PK BIS 4.09836
28 6HOY AR6 4.09836
29 6HOY TSN 4.09836
30 4X6I 3Y1 4.09836
31 3TKY SAH 4.09836
32 5MQ5 ASP 4.09836
33 5I3B HQE 4.09836
34 2A8X FAD 4.09836
35 3VPH OXM 4.19355
36 3VPH NAD 4.19355
37 3CW9 01A 4.91803
38 4O4F IHP 4.91803
39 4O4F ATP 4.91803
40 2PUL ACP 4.91803
41 4ZGS NAD 4.91803
42 3P3G UKW 4.91803
43 3P3G 3P3 4.91803
44 4KGD FAD 4.91803
45 4KGD TDP 4.91803
46 3KLJ FAD 4.91803
47 3NZK C90 4.91803
48 1ZEM NAD 4.91803
49 3AY6 NAI 4.91803
50 1A5Z NAD 4.91803
51 2Q3R FMN 4.91803
52 5U8U FAD 4.91803
53 3GDN FAD 4.91803
54 4GN8 ASO 4.91803
55 4EMI FAD 4.91803
56 4FL3 ANP 4.91803
57 2XVF FAD 4.91803
58 4GKY MAN 4.91803
59 4O33 TZN 5.7377
60 4O33 3PG 5.7377
61 3STK PLM 5.7377
62 4HKP TKW 5.7377
63 3CGB FAD 5.7377
64 4L77 CNL 5.7377
65 2XVE FAD 5.7377
66 3C6K SPD 5.7377
67 3C6K MTA 5.7377
68 1VPE ANP 5.7377
69 4U36 TNR 5.7377
70 3QV1 NAD 5.7377
71 2VAP GDP 5.7377
72 1RM4 NDP 5.7377
73 5GSN MMZ 5.7377
74 5GSN FAD 5.7377
75 5GSN NAP 5.7377
76 5EYY MDM 6.55738
77 2PHU MAN MAN 6.55738
78 2GMP NAG MAN 6.55738
79 2GNM MAN 6.55738
80 2GND MAN 6.55738
81 1Q8V MAN MAN MAN 6.55738
82 1Q8O MAN MMA 6.55738
83 2GNB MAN 6.55738
84 1Q8V MAN MAN 6.55738
85 2PHU MAN MAN MAN BMA MAN 6.55738
86 2PHR MAN MAN BMA MAN 6.55738
87 2PHF MAN MAN BMA MAN 6.55738
88 2PHT MAN MAN MAN BMA MAN 6.55738
89 2GND MAN MMA 6.55738
90 2PHW MAN MAN 6.55738
91 2PHR MAN MAN 6.55738
92 2PHF MAN MAN 6.55738
93 2PHW MAN MAN MAN BMA MAN MAN MAN 6.55738
94 2PHT MAN MAN MAN 6.55738
95 1Q8P MAN MMA 6.55738
96 2AUY NAG MAN MMA 6.55738
97 2AR6 NAG MAN MAN MAN NAG 6.55738
98 2GN3 MAN 6.55738
99 2AR6 NAG MAN 6.55738
100 3ZYR NAG NAG BMA MAN MAN NAG NAG 6.55738
101 2GN3 MMA 6.55738
102 3ZYR ASN NAG NAG BMA MAN MAN NAG NAG 6.55738
103 2GMM MAN MAN 6.55738
104 1Q8Q MAN MMA 6.55738
105 1UKG MMA 6.55738
106 1Q8S MAN MMA 6.55738
107 1LOF MAN BMA NAG NAG MAN NAG GAL GAL 6.55738
108 2PHX MAN MAN MAN MAN 6.55738
109 2PHX MAN MAN 6.55738
110 1LOB MMA 6.55738
111 3NKS FAD 6.55738
112 5L4S NAP 6.55738
113 5L4S 6KX 6.55738
114 2R4J FAD 6.55738
115 2R4J 13P 6.55738
116 2YVF NAD 6.55738
117 1OFD AKG 6.55738
118 6GAR FAD 6.55738
119 2CUN 3PG 6.55738
120 5A1S FLC 6.55738
121 2HJR APR 6.55738
122 1OFD FMN 6.55738
123 5YLT SFG 6.55738
124 1GUZ NAD 6.55738
125 2D3S TNR 6.55738
126 5NNA BZM 6.55738
127 1WPQ NAD 6.55738
128 2OFD NGA 7.04225
129 5OVL NAP 7.37705
130 5OVK NDP 7.37705
131 4RPL 3UC 7.37705
132 4RPL FAD 7.37705
133 6A3J NAI 7.37705
134 6A3J SOE 7.37705
135 5U3B 7TD 7.37705
136 4D42 NAP 7.37705
137 4D42 W0I 7.37705
138 1LVW TYD 7.37705
139 1T3Q FAD 7.37705
140 1BXG NAD 7.37705
141 1F8G NAD 7.37705
142 4UX9 ANP 7.37705
143 2RGO FAD 7.37705
144 5WS9 AMP 7.37705
145 2JDR L20 7.37705
146 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 7.37705
147 4M00 SUC 8.19672
148 1AE1 NAP 8.19672
149 5Z20 NAI 8.19672
150 5DEX 5E0 8.19672
151 1RYI GOA 8.19672
152 1RYI FAD 8.19672
153 2VPQ ANP 8.19672
154 4MRT COA 8.19672
155 2VBU CDP 8.19672
156 2YY7 NAD 8.19672
157 1WMA AB3 9.01639
158 1WMA NDP 9.01639
159 1YKF NAP 9.01639
160 5J5Z FAD 9.01639
161 2F5Z FAD 9.01639
162 2PI8 NAG NAG NAG NAG NAG NAG 9.01639
163 4PLG NAI 9.01639
164 4PLG OXM 9.01639
165 2A92 NAI 9.01639
166 1Q9I TEO 9.01639
167 1Q9I FAD 9.01639
168 4POO SAM 9.01639
169 2NU8 COA 9.01639
170 1LDN NAD 9.01639
171 1NLU IVA PHI TYB 9.01639
172 2IVN ANP 9.01639
173 1KAO GDP 9.58084
174 5AB7 MLC 9.83607
175 1LYX PGA 9.83607
176 5F52 ASP 9.83607
177 3UCL CYH 9.83607
178 3UCL FAD 9.83607
179 3UCL NAP 9.83607
180 2UYT ADP 9.83607
181 2UYT LRH 9.83607
182 2Q6B HR2 9.83607
183 1U6R ADP 9.83607
184 4K81 GTP 9.83607
185 2YVJ FAD 10.0917
186 1MVQ MMA 10.6557
187 4DQ2 BTX 10.6557
188 6CEP NAD 10.6557
189 6CEP OXM 10.6557
190 3GF4 UPG 10.6557
191 1D4D FAD 10.6557
192 1ZK4 AC0 10.6557
193 1O94 ADP 10.6557
194 1VRP ADP 10.6557
195 3GF4 FAD 10.6557
196 3OEN GLU 10.6557
197 1G55 SAH 10.6557
198 6D5H GNP 11.3772
199 6DIO NAD 11.4754
200 2Z6J FMN 11.4754
201 5GZ6 7C3 11.4754
202 5GZ6 NDP 11.4754
203 1PFK ADP 11.4754
204 2Q4W FAD 11.4754
205 1KEV NDP 12.2951
206 5WGR FAD 12.2951
207 5X8G S0N 12.2951
208 2RAB FAD 12.2951
209 2UZ1 TPP 12.2951
210 1BW9 NAD 13.1148
211 1EQ2 NAP 13.1148
212 1C1X NAD 13.1148
213 2VQD AP2 13.1148
214 1E6E FAD 13.1148
215 1EZ4 NAD 13.1148
216 4HDO GNP 13.1148
217 3EWP APR 13.1148
218 3QMN COA 13.1148
219 3RNM FAD 13.7931
220 4PLT OXM 13.9344
221 1GUA GNP 13.9344
222 4C3Y FAD 13.9344
223 4PLT NAI 13.9344
224 4C3Y ANB 13.9344
225 5ERG SAM 13.9344
226 1FIQ FAD 13.9344
227 4BG4 ADP 13.9344
228 3JQ8 NAP 13.9344
229 6FDF SAH 13.9344
230 1LTH NAD 13.9344
231 3NRZ FAD 13.9344
232 5GLN XYS 14.7541
233 1M15 ADP 14.7541
234 1M15 ARG 14.7541
235 1TZJ A3B 14.7541
236 1N62 FAD 14.7541
237 3HDY FDA 15.5738
238 3HDY FAD 15.5738
239 5NMX NAP 15.5738
240 5NMX FAD 15.5738
241 5TS5 FAD 15.5738
242 3O26 NDP 17.2131
243 1FL2 FAD 17.2131
244 3JQ3 ADP 17.2131
245 3AXK NDP 18.0328
246 2JK0 ASP 18.0328
247 2X6T NAP 18.8525
248 5V6F MAN BMA MAN 19.6721
249 4YRY FAD 19.6721
250 3ZEI AWH 19.6721
251 4YRY NAD 19.6721
252 1FNZ A2G 19.6721
253 1C0I BE2 19.6721
254 1C0I FAD 19.6721
255 5W3K NDP 19.6721
256 5W3K 9TY 19.6721
257 2FMD MAN MAN 20.4918
258 1ELI PYC 21.3115
259 6GAS FAD 21.3115
260 3QDW A2G 21.3115
261 3QDV A2G 21.3115
262 3ENG CBI 22.1311
263 1XXR MAN 23.7705
264 1VBO MAN 24.5902
265 1VBO MAN MAN MAN 24.5902
266 1JOT GAL A2G 24.5902
267 4J56 FAD 24.5902
268 6CGD AKN 24.5902
269 6CGD GNP 24.5902
270 1C3M MAN MAN 34.4262
271 1WS5 MMA 37.7049
272 1WS4 AMG 37.7049
273 1WS4 GYP 37.7049
274 1UGY GLA BGC 37.7049
275 1KUJ MMA 37.7049
276 1UGY GLA GLC 37.7049
277 1UGW GAL 37.7049
278 1M26 GAL A2G 37.7049
279 1JAC AMG 37.7049
280 1UGX GAL MGC 37.7049
281 5Z75 NAD 37.7049
282 1TOQ AMG 40.1639
283 6FLZ MMA 45.082
284 2BMZ XLM 48.3607
Pocket No.: 2; Query (leader) PDB : 2NU5; Ligand: NAG; Similar sites found with APoc: 167
This union binding pocket(no: 2) in the query (biounit: 2nu5.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2GJ5 VD3 None
2 3O61 GDD None
3 3BGD PM6 None
4 3BGD SAH None
5 5ZBL AMP None
6 1VL0 NAI None
7 2CVQ NDP 1.63934
8 1O0S NAI 1.63934
9 3CH6 NAP 1.63934
10 3CH6 311 1.63934
11 2JAP NDP 1.63934
12 3RFV 15L 2.45902
13 3RFV NAI 2.45902
14 2ZC0 PMP 2.45902
15 2O4C NAD 2.45902
16 5I39 FAD 3.27869
17 1PN0 FAD 3.27869
18 1PN0 IPH 3.27869
19 5O98 NAP 3.27869
20 2ZIF SAM 3.27869
21 4JWH SAH 3.27869
22 4JWF SAH 3.27869
23 5JIC ADP 3.27869
24 4QT2 RAP 3.27869
25 3RG9 NDP 3.27869
26 4YNU FAD 4.09836
27 3NYC FAD 4.09836
28 3NYC IAR 4.09836
29 1H82 FAD 4.09836
30 1YKJ FAD 4.09836
31 2I0K FAD 4.09836
32 1Z82 NDP 4.09836
33 1XKQ NDP 4.09836
34 3GDN HBX 4.91803
35 4EMI NAD 4.91803
36 1QO8 FAD 4.91803
37 1SB8 NAD 4.91803
38 1SB8 UD2 4.91803
39 5E1M SAH 4.91803
40 5E1M PRO PRO LYS ARG ILE ALA 4.91803
41 3ICR FAD 4.91803
42 3ICS FAD 4.91803
43 3B20 NAD 4.91803
44 4J7U YTZ 4.91803
45 4J7U NAP 4.91803
46 5OOH NAP 4.91803
47 5OOH 9ZZ 4.91803
48 5EEH SAH 4.91803
49 5EEH P9P 4.91803
50 5YJF 8WO 4.91803
51 5YJF SAH 4.91803
52 3LST SAH 4.91803
53 5VN0 NAI 4.91803
54 2AE2 PTO 5.7377
55 2AE2 NAP 5.7377
56 6F97 FAD 5.7377
57 5YJI SAH 5.7377
58 1ZGA SAH 5.7377
59 5YJI 8WO 5.7377
60 5ICE 2H4 5.7377
61 5ICE SAH 5.7377
62 1UXG FUM 5.7377
63 1UXG NAD 5.7377
64 2O3Z AI7 5.7377
65 4OOE NDP 5.7377
66 4OOE FOM 5.7377
67 1OAA OAA 5.7377
68 3KO8 NAD 5.7377
69 1TUU ADP 5.7377
70 1XSE NDP 5.7377
71 4EI7 GDP 5.7377
72 1RPN NDP 6.26866
73 1FP1 SAH 6.55738
74 6FP4 E1T 6.55738
75 6FP4 FAD 6.55738
76 5NUE NAD 6.55738
77 5NUF NAD 6.55738
78 2YVF FAD 6.55738
79 1GV0 NAD 6.55738
80 3AAQ ARU 6.55738
81 3T7S SAM 6.55738
82 4O0L NDP 6.55738
83 1V59 FAD 6.55738
84 5LD5 NAD 6.55738
85 1N5D NDP 7.37705
86 2GOU FMN 7.37705
87 2C5A GDC 7.37705
88 2C5A NAD 7.37705
89 3LAD FAD 7.37705
90 4JDR FAD 7.37705
91 5EOW FAD 7.37705
92 3LU1 NAD 7.37705
93 1RRM APR 7.37705
94 2OOR NAD 7.37705
95 5JY6 NAD 7.37705
96 1E3W NAD 7.37705
97 2VD9 EPC 7.37705
98 2VD9 IN5 7.37705
99 1X7D NAD 7.37705
100 2B4R NAD 7.37705
101 2B4R AES 7.37705
102 3AI8 HNQ 7.37705
103 5BRT CH9 8.19672
104 5BRT FAD 8.19672
105 6C4M NAP 8.19672
106 5ZZ6 ADP 8.19672
107 4M52 M52 8.19672
108 4M52 FAD 8.19672
109 1GPM CIT 8.19672
110 4EXS X8Z 8.19672
111 4MDH NAD 8.19672
112 4E70 N7I 8.19672
113 2GCG NDP 8.19672
114 5MDH NAD 8.19672
115 4AP3 FAD 9.01639
116 4AP3 NAP 9.01639
117 5TUK FAD 9.01639
118 2Y6Q I7T 9.01639
119 5GM9 CBK 9.01639
120 1YQZ FAD 9.83607
121 5JWC FAD 9.83607
122 1JQD SAH 9.83607
123 1JQD HSM 9.83607
124 4CQM NAP 9.83607
125 2AOT SAH 9.83607
126 3LXD FAD 9.83607
127 5X20 NAD 9.83607
128 3AB1 FAD 9.83607
129 2FR1 NDP 9.83607
130 2YVJ NAI 10.0917
131 1B8U NAD 10.3343
132 5OE4 3UK 10.6557
133 1QZZ SAM 10.6557
134 3P9C SAH 11.4754
135 2FLI DX5 11.4754
136 1NAA 6FA 11.4754
137 1NAA ABL 11.4754
138 1G0N NDP 11.4754
139 4Z24 FAD 11.4754
140 3I53 SAH 11.4754
141 3GFB NAD 12.2951
142 2Q1W NAD 12.2951
143 1H9A NAP 12.2951
144 1KYZ SAH 13.1148
145 1KYZ FER 13.1148
146 1LVL FAD 13.1148
147 1C1D PHE 13.1148
148 4AT0 FAD 13.9344
149 5FJN FAD 13.9344
150 5FJN BE2 13.9344
151 1U7T NAD 13.9344
152 4I4Z 2NE 13.9344
153 2Q7V FAD 14.7541
154 3WGT FAD 14.7541
155 3WGT QSC 14.7541
156 4MOP 2H5 15.5738
157 4DXD GDP 15.5738
158 4IQY AR6 15.5738
159 2QA1 FAD 16.3934
160 1FP2 HMO 16.3934
161 1FP2 SAH 16.3934
162 1KGQ NPI 17.2131
163 1KGQ SCO 17.2131
164 5OC1 FAD 17.2131
165 3SSO SAH 18.0328
166 5HSA FAS 23.7705
167 1RM0 D6P 27.0492
Pocket No.: 3; Query (leader) PDB : 2NU5; Ligand: NAG; Similar sites found with APoc: 69
This union binding pocket(no: 3) in the query (biounit: 2nu5.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4YMH SAH 1.63934
2 6BSX GDP 2.45902
3 1ZK7 FAD 3.27869
4 2PT9 S4M 3.27869
5 2PT9 2MH 3.27869
6 4MIG G3F 3.27869
7 6GKV SAH 4.09836
8 1XDS SAM 4.09836
9 1XHC FAD 4.09836
10 2RGJ FAD 4.09836
11 3ITJ FAD 4.09836
12 4HA6 FAD 4.91803
13 5KVA SAM 4.91803
14 2ZPA ACO 4.91803
15 2B1N LYS ALA SER VAL GLY 4.91803
16 1M7Y PPG 4.91803
17 3L4S NAD 4.91803
18 3L4S 3PG 4.91803
19 2ZXI FAD 5.7377
20 2GMH FAD 5.7377
21 2F5T MAL 5.7377
22 3AB4 THR 5.7377
23 4U9U FAD 5.7377
24 1QPG MAP 5.7377
25 6F7L FAD 6.55738
26 1YQS BSA 6.55738
27 2D7I NGA 7.37705
28 5J60 FAD 7.37705
29 5HXI 5HN 7.37705
30 1BXG HCI 7.37705
31 4IXW IXW 7.37705
32 5MSD BEZ 8.19672
33 5SWB NAG BMA MAN MAN MAN MAN 8.19672
34 2Y6Q FAD 9.01639
35 1NVM NAD 9.83607
36 2DFV NAD 9.83607
37 3GMB FAD 9.83607
38 1VGR COA 9.83607
39 1XI9 PLP 9.83607
40 1B8U OAA 10.3343
41 5ZAI COA 10.6557
42 3GDH MGP 10.6557
43 6FA4 GNP 10.9827
44 4USR FAD 11.4754
45 4Z0H NAD 11.4754
46 1MHW BP4 CYS DAR TYR PEA 11.9048
47 3DUW SAH 12.2951
48 5LOG SAH 12.2951
49 1C7R PA5 12.2951
50 3OZ2 FAD 12.2951
51 5WPJ NDP 13.9344
52 1U7T TDT 13.9344
53 5ZW3 SAH 13.9344
54 1ZC3 GNP 13.9344
55 4CM9 NAP 13.9344
56 1TUF AZ1 13.9344
57 5GLN XYP XYP XYP 14.7541
58 2IID PHE 14.7541
59 2IID FAD 14.7541
60 2RCU BUJ 14.7541
61 1P4A PCP 14.7541
62 1RP7 TZD 17.2131
63 4BV6 FAD 18.8525
64 5FPE 3TR 19.6721
65 3PT9 SAH 19.6721
66 1PJS NAD 21.3115
67 4MSG 2C6 21.3115
68 3CTY FAD 21.3115
69 4UP3 FAD 27.0492
Pocket No.: 4; Query (leader) PDB : 2NU5; Ligand: NAG; Similar sites found with APoc: 65
This union binding pocket(no: 4) in the query (biounit: 2nu5.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4WOP CTP None
2 5Z2L NDP None
3 2B4B COA None
4 3W2E FAD 1.63934
5 3W2E NAD 1.63934
6 3GD4 FAD 2.45902
7 3GD4 NAD 2.45902
8 1O8B ABF 3.27869
9 2JB2 PHE 4.91803
10 2JB2 FAD 4.91803
11 4K5S PM0 4.91803
12 4K5S FAD 4.91803
13 3ICS ADP 4.91803
14 3K56 IS3 4.91803
15 2BNE U5P 4.91803
16 2HQM FAD 5.7377
17 5TWB FAD 5.7377
18 2YYY NAP 5.7377
19 2PWY SAH 5.7377
20 2R14 TXD 5.7377
21 2R14 FMN 5.7377
22 2CUL FAD 6.55738
23 5K4G ASP 6.55738
24 5NDF LU2 6.55738
25 5NDF UDP 6.55738
26 3X0V FAD 6.55738
27 5I60 67W 7.37705
28 4KQ6 DLZ 7.37705
29 4D9C PMP 7.37705
30 2ABJ CBC 8.19672
31 3UZO GLU 8.19672
32 5T2U NAP 9.01639
33 5KOX FAD 9.01639
34 5KOX RFP 9.01639
35 3E1T FAD 9.01639
36 1VDC FAD 9.01639
37 6N35 MAN MAN 9.83607
38 2WLT ASP 9.83607
39 5THQ NDP 9.83607
40 1M2W NAD 9.83607
41 1JXN MFU 9.83607
42 4X9M FAD 9.83607
43 4XQC 13D 10.6557
44 4XQC NAD 10.6557
45 3CIF NAD 10.6557
46 2IVD FAD 11.4754
47 5BSR AMP 11.4754
48 5BSR COA 11.4754
49 3I54 CMP 11.4754
50 4L8V NAP 11.4754
51 2HIM ASN 12.2951
52 2RAB NAD 12.2951
53 2HIM ASP 12.2951
54 5FOI MY8 12.2951
55 3LZW FAD 12.2951
56 5UR0 NAD 12.2951
57 5X68 FAD 13.1148
58 4OM8 NAD 13.1148
59 5K0A FAD 13.1148
60 5DNC ASN 13.9344
61 4R8L ASP 13.9344
62 1DQX BMP 13.9344
63 1IYE PGU 18.0328
64 2WET FAD 19.6721
65 1KPG SAH 26.2295
Pocket No.: 5; Query (leader) PDB : 2NU5; Ligand: NAG; Similar sites found with APoc: 39
This union binding pocket(no: 5) in the query (biounit: 2nu5.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 1U8Z GDP 2.45902
2 2I7C AAT 3.27869
3 4YKG FAD 4.09836
4 5TTJ FAD 4.09836
5 2DT9 THR 4.09836
6 1H6C NDP 4.91803
7 1H6C SIN 4.91803
8 3ICT FAD 4.91803
9 3EYA FAD 4.91803
10 6F3M NAD 6.55738
11 1V59 NAD 6.55738
12 3RDO BTN 6.55738
13 6CI9 NAP 7.37705
14 6GNC FAD 7.37705
15 1X7D ORN 7.37705
16 1RVV INI 7.37705
17 1F76 FMN 8.19672
18 2WPU KYT 8.19672
19 1M5B BN1 9.01639
20 1TDF FAD 9.01639
21 3Q9T FAY 9.83607
22 1T26 GBD 9.83607
23 1T26 NAI 9.83607
24 3PFD FDA 9.83607
25 4D9M 0JO 10.6557
26 3B6R ADP 10.6557
27 5NUL FMN 10.8696
28 4TXI FAD 11.4754
29 4IPE ANP 11.4754
30 3OND NAD 13.1148
31 3OND ADN 13.1148
32 4ONQ SFG 13.1148
33 2VZ0 NAP 13.9344
34 2VZ0 D64 13.9344
35 5K6A NAP 13.9344
36 3JQF NAP 13.9344
37 4CLO NAP 13.9344
38 4EKV BTN 14.7541
39 2PEL LBT 24.5902
Pocket No.: 6; Query (leader) PDB : 2NU5; Ligand: NAG; Similar sites found with APoc: 52
This union binding pocket(no: 6) in the query (biounit: 2nu5.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2B4D COA None
2 4B5P ACO None
3 1Q0H FOM None
4 1Q0H NDP None
5 1TPY SAH 2.45902
6 3A7R LAQ 3.27869
7 2QV7 ADP 3.27869
8 3V1Y NAD 4.09836
9 4U8P UDP 4.09836
10 4U8P FDA 4.09836
11 5YU3 PRO 4.09836
12 5YU3 NAD 4.09836
13 3EYA TDP 4.91803
14 5XVH NAP 4.91803
15 1GAD NAD 4.91803
16 4KWI NAP 4.91803
17 2D2I NAP 4.91803
18 4ZCC FAD 4.91803
19 5Y77 FAD 5.7377
20 1KC7 PPR 5.7377
21 3QFA FAD 6.55738
22 1GPE FAD 6.55738
23 1L3I SAH 6.55738
24 1O6Z NAD 6.55738
25 1CER NAD 7.37705
26 3CQD ATP 8.19672
27 2VYN NAD 8.19672
28 3H9E NAD 8.19672
29 2P53 NNG 8.19672
30 1DZK PRZ 9.01639
31 2XYQ SAH 9.01639
32 1MJH ATP 9.01639
33 4A6D SAM 9.83607
34 1KYV RBF 9.83607
35 2ZUX RAM 10.6557
36 3C1O NAP 10.6557
37 1OYB HBA 11.4754
38 1OYB FMN 11.4754
39 2WPF WPF 12.2951
40 2WPF FAD 12.2951
41 3NRR D16 13.1148
42 3NRR NAP 13.1148
43 2GAG NAD 13.1148
44 1DSS NAD 13.1148
45 5MQ6 NDP 13.1148
46 1I9G SAM 13.9344
47 3MB5 SAM 14.7541
48 1WP4 NDP 16.3934
49 1H74 ILE 17.2131
50 1IBR GNP 17.2131
51 1KPH SAH 27.0492
52 1GTE FAD 29.5082
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