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Receptor
PDB id Resolution Class Description Source Keywords
2NUO 1.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF A COMPLEX OF GRIFFITHSIN WITH GLUCOSE GRIFFITHSIA GRIFFITHSIN LECTINS DOMAIN SWAPPING MANNOSE BINDING HIVSUGAR BINDING PROTEIN
Ref.: CRYSTALLOGRAPHIC STUDIES OF THE COMPLEXES OF ANTIVI PROTEIN GRIFFITHSIN WITH GLUCOSE AND N-ACETYLGLUCOS PROTEIN SCI. V. 16 1485 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BGC A:301;
A:302;
A:303;
B:304;
B:305;
B:306;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
submit data
180.156 C6 H12 O6 C([C@...
EDO A:402;
Invalid;
none;
submit data
62.068 C2 H6 O2 C(CO)...
SO4 A:401;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2NUO 1.5 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF A COMPLEX OF GRIFFITHSIN WITH GLUCOSE GRIFFITHSIA GRIFFITHSIN LECTINS DOMAIN SWAPPING MANNOSE BINDING HIVSUGAR BINDING PROTEIN
Ref.: CRYSTALLOGRAPHIC STUDIES OF THE COMPLEXES OF ANTIVI PROTEIN GRIFFITHSIN WITH GLUCOSE AND N-ACETYLGLUCOS PROTEIN SCI. V. 16 1485 2007
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2NUO - BGC C6 H12 O6 C([C@@H]1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2NUO - BGC C6 H12 O6 C([C@@H]1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2NUO - BGC C6 H12 O6 C([C@@H]1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: BGC; Similar ligands found: 142
No: Ligand ECFP6 Tc MDL keys Tc
1 WOO 1 1
2 GLC 1 1
3 BGC 1 1
4 ALL 1 1
5 BMA 1 1
6 GXL 1 1
7 GIV 1 1
8 GAL 1 1
9 MAN 1 1
10 GLA 1 1
11 Z6J 0.653846 0.866667
12 32O 0.653846 0.866667
13 RIB 0.653846 0.866667
14 FUB 0.653846 0.866667
15 AHR 0.653846 0.866667
16 MLB 0.511628 0.848485
17 GLC GLC 0.511628 0.848485
18 BGC GLC 0.511628 0.848485
19 BGC GLA 0.511628 0.848485
20 GLA BMA 0.511628 0.848485
21 MAN BMA 0.511628 0.848485
22 BMA GLA 0.511628 0.848485
23 GLA BGC 0.511628 0.848485
24 MAN MAN 0.511628 0.848485
25 GLA GLC 0.511628 0.848485
26 BMA MAN 0.511628 0.848485
27 GAL GLC 0.511628 0.848485
28 GAL GAL 0.511628 0.848485
29 LAK 0.511628 0.848485
30 GLC BGC 0.511628 0.848485
31 YDR 0.5 0.8
32 GLC GLC GLC GLC BGC 0.488889 0.848485
33 GLC GLC GLC 0.488889 0.848485
34 MAN MAN MAN 0.488889 0.848485
35 BMA MAN MAN 0.488889 0.848485
36 GLC GLC GLC GLC GLC BGC 0.488889 0.848485
37 EMZ 0.472222 0.794118
38 BG6 0.461538 0.675
39 BGP 0.461538 0.675
40 G6P 0.461538 0.675
41 M6P 0.461538 0.675
42 M6D 0.461538 0.675
43 A6P 0.461538 0.675
44 GAF 0.457143 0.875
45 SHG 0.457143 0.875
46 2FG 0.457143 0.875
47 G2F 0.457143 0.875
48 2H5 0.457143 0.875
49 GCS 0.457143 0.777778
50 1GN 0.457143 0.777778
51 X6X 0.457143 0.777778
52 PA1 0.457143 0.777778
53 95Z 0.457143 0.777778
54 G3F 0.457143 0.875
55 NGR 0.454545 0.848485
56 MAL 0.454545 0.848485
57 MAN GLC 0.454545 0.848485
58 GAL BGC 0.454545 0.848485
59 GLA GLA 0.454545 0.848485
60 BGC BMA 0.454545 0.848485
61 M3M 0.454545 0.848485
62 GLA GAL 0.454545 0.848485
63 MAB 0.454545 0.848485
64 GLC GAL 0.454545 0.848485
65 B2G 0.454545 0.848485
66 LBT 0.454545 0.848485
67 BMA GAL 0.454545 0.848485
68 LAT 0.454545 0.848485
69 BGC GAL 0.454545 0.848485
70 CBI 0.454545 0.848485
71 CBK 0.454545 0.848485
72 N9S 0.454545 0.848485
73 LB2 0.454545 0.848485
74 3MG 0.444444 0.875
75 TCB 0.444444 0.8
76 GLC SGC 0.444444 0.8
77 YIO 0.441176 0.870968
78 2GS 0.432432 0.875
79 2M4 0.431818 0.848485
80 AHR AHR 0.428571 0.764706
81 GLF 0.428571 0.84375
82 FUB AHR 0.428571 0.764706
83 MAN BMA BMA 0.416667 0.848485
84 BMA MAN BMA 0.416667 0.848485
85 CTR 0.416667 0.848485
86 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.416667 0.848485
87 GLA GAL BGC 0.416667 0.848485
88 CE5 0.416667 0.848485
89 MLR 0.416667 0.848485
90 CE6 0.416667 0.848485
91 MT7 0.416667 0.848485
92 BMA BMA BMA 0.416667 0.848485
93 GLC BGC BGC BGC BGC 0.416667 0.848485
94 MAN MAN BMA BMA BMA BMA 0.416667 0.848485
95 BGC BGC BGC BGC BGC 0.416667 0.848485
96 BGC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
97 BGC GLC GLC 0.416667 0.848485
98 BMA BMA BMA BMA BMA 0.416667 0.848485
99 MAN BMA BMA BMA BMA 0.416667 0.848485
100 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.416667 0.848485
101 GLC BGC BGC BGC BGC BGC 0.416667 0.848485
102 MAN BMA BMA BMA BMA BMA 0.416667 0.848485
103 BGC BGC BGC BGC BGC BGC 0.416667 0.848485
104 BGC GLC GLC GLC 0.416667 0.848485
105 BGC BGC BGC GLC 0.416667 0.848485
106 CTT 0.416667 0.848485
107 GLA GAL GLC 0.416667 0.848485
108 MTT 0.416667 0.848485
109 GLC BGC BGC BGC 0.416667 0.848485
110 GLC GLC BGC 0.416667 0.848485
111 CEY 0.416667 0.848485
112 B4G 0.416667 0.848485
113 CE8 0.416667 0.848485
114 BMA BMA BMA BMA BMA BMA 0.416667 0.848485
115 GAL FUC 0.416667 0.848485
116 DXI 0.416667 0.848485
117 GLC BGC GLC 0.416667 0.848485
118 CT3 0.416667 0.848485
119 GAL GAL GAL 0.416667 0.848485
120 GLC GLC GLC GLC GLC 0.416667 0.848485
121 BGC BGC BGC BGC 0.416667 0.848485
122 BGC BGC BGC 0.416667 0.848485
123 BGC BGC GLC 0.416667 0.848485
124 CEX 0.416667 0.848485
125 GLC GAL GAL 0.416667 0.848485
126 BGC GLC GLC GLC GLC 0.416667 0.848485
127 GLC BGC BGC 0.416667 0.848485
128 GS1 GLC GS1 0.408163 0.8
129 SGC SGC BGC 0.408163 0.8
130 BGC BGC BGC GLC BGC BGC 0.408163 0.848485
131 GLC BGC BGC BGC BGC BGC BGC 0.408163 0.848485
132 1LL 0.405405 0.771429
133 TDG 0.405405 0.771429
134 TRE 0.405405 0.848485
135 NDG 0.404762 0.7
136 NGA 0.404762 0.7
137 NAG 0.404762 0.7
138 HSQ 0.404762 0.7
139 A2G 0.404762 0.7
140 BM3 0.404762 0.7
141 FUB AHR AHR 0.4 0.764706
142 AHR AHR AHR AHR AHR AHR 0.4 0.764706
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2NUO; Ligand: BGC; Similar sites found with APoc: 333
This union binding pocket(no: 1) in the query (biounit: 2nuo.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 1LES GLC FRU None
2 2BQP GLC None
3 1OFS SUC None
4 2HMT NAI None
5 1WPY BTN None
6 5Z2L NDP None
7 3CH6 311 1.63934
8 3CH6 NAP 1.63934
9 2JE7 XMM 2.45902
10 2ZC0 PMP 2.45902
11 3GD4 NAD 2.45902
12 3GD4 FAD 2.45902
13 5N81 8Q2 2.45902
14 3OU2 SAH 3.27869
15 1PZG A3D 3.27869
16 1O8B ABF 3.27869
17 3RG9 NDP 3.27869
18 5BUK FAD 4.09836
19 5MQ5 ASP 4.09836
20 3TKY SAH 4.09836
21 4MO2 FDA 4.09836
22 4MO2 FAD 4.09836
23 1XDS SAM 4.09836
24 4YKG FAD 4.09836
25 1VFS DCS 4.09836
26 5YU3 PRO 4.09836
27 5YU3 NAD 4.09836
28 5ZYN FAD 4.09836
29 2RGJ FAD 4.09836
30 6FFI D8B 4.09836
31 4U8P UDP 4.09836
32 4U8P FDA 4.09836
33 16PK BIS 4.09836
34 3VPH NAD 4.19355
35 2JB2 PHE 4.91803
36 2JB2 FAD 4.91803
37 4O4F IHP 4.91803
38 4O4F ATP 4.91803
39 4K5S PM0 4.91803
40 4K5S FAD 4.91803
41 3KLJ FAD 4.91803
42 3NZK C90 4.91803
43 5VN0 NAI 4.91803
44 4ZGS NAD 4.91803
45 3P3G UKW 4.91803
46 3P3G 3P3 4.91803
47 5U8U FAD 4.91803
48 1A5Z NAD 4.91803
49 3B20 NAD 4.91803
50 3LST SAH 4.91803
51 3ICS ADP 4.91803
52 1ZEM NAD 4.91803
53 2PUL ACP 4.91803
54 2Q3R FMN 4.91803
55 3CW9 01A 4.91803
56 3K56 IS3 4.91803
57 4ZCC FAD 4.91803
58 2BNE U5P 4.91803
59 3L4S NAD 4.91803
60 3L4S 3PG 4.91803
61 5EEH P9P 4.91803
62 5EEH SAH 4.91803
63 3GDN FAD 4.91803
64 3EYA FAD 4.91803
65 3EYA TDP 4.91803
66 2ZXI FAD 5.7377
67 2HQM FAD 5.7377
68 3STK PLM 5.7377
69 1ZGA SAH 5.7377
70 4OOE NDP 5.7377
71 5TWB FAD 5.7377
72 2PWY SAH 5.7377
73 2YYY NAP 5.7377
74 4HKP TKW 5.7377
75 4O33 TZN 5.7377
76 4O33 3PG 5.7377
77 6F97 FAD 5.7377
78 1RM4 NDP 5.7377
79 3QV1 NAD 5.7377
80 5ICE 2H4 5.7377
81 5ICE SAH 5.7377
82 3C6K SPD 5.7377
83 3C6K MTA 5.7377
84 4L77 CNL 5.7377
85 2GN3 MAN 6.55738
86 2PHF MAN MAN BMA MAN 6.55738
87 2PHF MAN MAN 6.55738
88 2GN3 MMA 6.55738
89 2GNB MAN 6.55738
90 2AR6 NAG MAN MAN MAN NAG 6.55738
91 3ZYR NAG NAG BMA MAN MAN NAG NAG 6.55738
92 3ZYR ASN NAG NAG BMA MAN MAN NAG NAG 6.55738
93 2GNM MAN 6.55738
94 2GMM MAN MAN 6.55738
95 1UKG MMA 6.55738
96 2PHU MAN MAN 6.55738
97 2GND MAN 6.55738
98 1LOF MAN BMA NAG NAG MAN NAG GAL GAL 6.55738
99 1Q8V MAN MAN 6.55738
100 1Q8O MAN MMA 6.55738
101 2PHT MAN MAN MAN 6.55738
102 5EYY MDM 6.55738
103 1Q8V MAN MAN MAN 6.55738
104 2PHW MAN MAN 6.55738
105 2PHX MAN MAN MAN MAN 6.55738
106 2GND MAN MMA 6.55738
107 1Q8P MAN MMA 6.55738
108 2PHR MAN MAN 6.55738
109 6F7L FAD 6.55738
110 2PHR MAN MAN BMA MAN 6.55738
111 2GMP NAG MAN 6.55738
112 1Q8Q MAN MMA 6.55738
113 2PHX MAN MAN 6.55738
114 1Q8S MAN MMA 6.55738
115 2PHT MAN MAN MAN BMA MAN 6.55738
116 2PHU MAN MAN MAN BMA MAN 6.55738
117 2CUL FAD 6.55738
118 1LOB MMA 6.55738
119 2PHW MAN MAN MAN BMA MAN MAN MAN 6.55738
120 3NKS FAD 6.55738
121 3SQP FAD 6.55738
122 2R4J FAD 6.55738
123 2R4J 13P 6.55738
124 6GAR FAD 6.55738
125 2AUY NAG MAN MMA 6.55738
126 5K4G ASP 6.55738
127 5A1S FLC 6.55738
128 2CUN 3PG 6.55738
129 3X0V FAD 6.55738
130 1GPE FAD 6.55738
131 2AR6 NAG MAN 6.55738
132 1FP1 SAH 6.55738
133 2HJR APR 6.55738
134 1L3I SAH 6.55738
135 1V59 FAD 6.55738
136 5LD5 NAD 6.55738
137 5NDF LU2 6.55738
138 5NDF UDP 6.55738
139 1OFD AKG 6.55738
140 2D3S TNR 6.55738
141 6CI9 NAP 7.37705
142 1BXG NAD 7.37705
143 5J60 FAD 7.37705
144 4RPL FAD 7.37705
145 4RPL 3UC 7.37705
146 5OVL NAP 7.37705
147 5I60 67W 7.37705
148 3AI8 HNQ 7.37705
149 5U3B 7TD 7.37705
150 2JDR GLY ARG PRO ARG THR THR SER PHE ALA GLU 7.37705
151 2JDR L20 7.37705
152 5JY6 NAD 7.37705
153 1LVW TYD 7.37705
154 5OVK NDP 7.37705
155 2D7I NGA 7.37705
156 2VD9 IN5 7.37705
157 2VD9 EPC 7.37705
158 4KQ6 DLZ 7.37705
159 6A3J SOE 7.37705
160 6A3J NAI 7.37705
161 1ZFJ IMP 7.37705
162 4M00 SUC 8.19672
163 1AE1 NAP 8.19672
164 1RYI FAD 8.19672
165 1RYI GOA 8.19672
166 5MDH NAD 8.19672
167 4E70 N7I 8.19672
168 5BRT FAD 8.19672
169 5BRT CH9 8.19672
170 4MDH NAD 8.19672
171 3CQD ATP 8.19672
172 3UZO GLU 8.19672
173 2ABJ CBC 8.19672
174 2VBU CDP 8.19672
175 4MRT COA 8.19672
176 5MST FUM 8.19672
177 2F5Z FAD 9.01639
178 5KOX RFP 9.01639
179 5KOX FAD 9.01639
180 5J5Z FAD 9.01639
181 1WMA AB3 9.01639
182 1WMA NDP 9.01639
183 3E1T FAD 9.01639
184 2IVN ANP 9.01639
185 1LDN NAD 9.01639
186 1Q9I FAD 9.01639
187 1Q9I TEO 9.01639
188 2PI8 NAG NAG NAG NAG NAG NAG 9.01639
189 1KAO GDP 9.58084
190 5F52 ASP 9.83607
191 2UYT LRH 9.83607
192 2UYT ADP 9.83607
193 5THQ NDP 9.83607
194 5AB7 MLC 9.83607
195 1LYX PGA 9.83607
196 5JWC FAD 9.83607
197 1NVM NAD 9.83607
198 4X9M FAD 9.83607
199 3UCL NAP 9.83607
200 3UCL CYH 9.83607
201 3UCL FAD 9.83607
202 6N35 MAN MAN 9.83607
203 1XI9 PLP 9.83607
204 1U6R ADP 9.83607
205 1NYT NAP 9.83607
206 3GMB FAD 9.83607
207 2AOT SAH 9.83607
208 2WLT ASP 9.83607
209 4A6D SAM 9.83607
210 1KYV RBF 9.83607
211 1FFU FAD 9.83607
212 4K81 GTP 9.83607
213 4CQM NAP 9.83607
214 1JQD HSM 9.83607
215 1JQD SAH 9.83607
216 3LXD FAD 9.83607
217 2YVJ FAD 10.0917
218 2YVJ NAI 10.0917
219 1MVQ MMA 10.6557
220 1QZZ SAM 10.6557
221 5ZAI COA 10.6557
222 1D4D FAD 10.6557
223 3C1O NAP 10.6557
224 1VRP ADP 10.6557
225 5E5U MLI 10.6557
226 5NII FAD 10.6557
227 3CIF NAD 10.6557
228 2ZUX RAM 10.6557
229 2CSN CKI 10.6557
230 6FA4 GNP 10.9827
231 2IVD FAD 11.4754
232 3P9C SAH 11.4754
233 2Z6J FMN 11.4754
234 5BSR COA 11.4754
235 5BSR AMP 11.4754
236 2FLI DX5 11.4754
237 1EP2 FMN 11.4754
238 1EP2 ORO 11.4754
239 1PFK ADP 11.4754
240 3I54 CMP 11.4754
241 2RAB FAD 12.2951
242 1KEV NDP 12.2951
243 2RAB NAD 12.2951
244 5WGR FAD 12.2951
245 1MO9 FAD 12.2951
246 1MO9 KPC 12.2951
247 2HIM ASP 12.2951
248 5FOI MY8 12.2951
249 3LZW FAD 12.2951
250 2HIM ASN 12.2951
251 5UR0 NAD 12.2951
252 2UZ1 TPP 12.2951
253 5XWV NDP 12.2951
254 5XWV 8H6 12.2951
255 1BW9 NAD 13.1148
256 5X68 FAD 13.1148
257 1C1X NAD 13.1148
258 3NRR NAP 13.1148
259 1KYZ SAH 13.1148
260 1EQ2 NAP 13.1148
261 3NRR D16 13.1148
262 3QMN COA 13.1148
263 2VQD AP2 13.1148
264 1EZ4 NAD 13.1148
265 4OM8 NAD 13.1148
266 5K0A FAD 13.1148
267 1LVL FAD 13.1148
268 1PVN MZP 13.1148
269 1E6E FAD 13.1148
270 3RNM FAD 13.7931
271 4C3Y FAD 13.9344
272 4C3Y ANB 13.9344
273 5WPJ NDP 13.9344
274 5DNC ASN 13.9344
275 1LTH NAD 13.9344
276 1GUA GNP 13.9344
277 4R8L ASP 13.9344
278 6FDF SAH 13.9344
279 1DQX BMP 13.9344
280 3JQ8 NAP 13.9344
281 1I9G SAM 13.9344
282 1F5N GNP 13.9344
283 2RCU BUJ 14.7541
284 1TZJ A3B 14.7541
285 2Q7V FAD 14.7541
286 1M15 ADP 14.7541
287 1M15 ARG 14.7541
288 1N62 FAD 14.7541
289 3MB5 SAM 14.7541
290 5GLN XYP XYP XYP 14.7541
291 5GLN XYS 14.7541
292 3HDY FAD 15.5738
293 5NMX NAP 15.5738
294 5NMX FAD 15.5738
295 5TS5 FAD 15.5738
296 1FL2 FAD 17.2131
297 3JQ3 ADP 17.2131
298 3AXK NDP 18.0328
299 2JK0 ASP 18.0328
300 1IYE PGU 18.0328
301 4BV6 FAD 18.8525
302 2X6T NAP 18.8525
303 5V6F MAN BMA MAN 19.6721
304 1C0I FAD 19.6721
305 1C0I BE2 19.6721
306 4YRY FAD 19.6721
307 3PT9 SAH 19.6721
308 2FMD MAN MAN 20.4918
309 1ELI PYC 21.3115
310 3CTY FAD 21.3115
311 6GAS FAD 21.3115
312 1PJS NAD 21.3115
313 1XXR MAN 23.7705
314 1VBO MAN 24.5902
315 1VBO MAN MAN MAN 24.5902
316 1JOT GAL A2G 24.5902
317 6CGD AKN 24.5902
318 6CGD GNP 24.5902
319 1KPG SAH 26.2295
320 1C3M MAN MAN 34.4262
321 1WS5 MMA 37.7049
322 1WS4 AMG 37.7049
323 1WS4 GYP 37.7049
324 1UGY GLA BGC 37.7049
325 1UGY GLA GLC 37.7049
326 1KUJ MMA 37.7049
327 1UGW GAL 37.7049
328 1JAC AMG 37.7049
329 1M26 GAL A2G 37.7049
330 1UGX GAL MGC 37.7049
331 1TOQ AMG 40.1639
332 6FLZ MMA 45.082
333 2BMZ XLM 48.3607
Pocket No.: 2; Query (leader) PDB : 2NUO; Ligand: BGC; Similar sites found with APoc: 108
This union binding pocket(no: 2) in the query (biounit: 2nuo.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 2GJ5 VD3 None
2 2DXU BT5 None
3 1N2X SAM None
4 2O07 SPD None
5 2O07 MTA None
6 4B5P ACO None
7 2CVQ NDP 1.63934
8 1HYH NAD 2.45902
9 3RFV NAI 2.45902
10 5BVA FAD 3.27869
11 5X9D 80F 3.27869
12 1DJN ADP 3.27869
13 5O98 NAP 3.27869
14 1SOW NAD 4.09836
15 6GKV SAH 4.09836
16 6AM8 TRP 4.09836
17 4YNU FAD 4.09836
18 4YNU LGC 4.09836
19 6HOY AR6 4.09836
20 6HOY TSN 4.09836
21 4X6I 3Y1 4.09836
22 2A8X FAD 4.09836
23 4TW7 37K 4.09836
24 3VPH OXM 4.19355
25 4KGD TDP 4.91803
26 4KGD FAD 4.91803
27 4EMI FAD 4.91803
28 4FL3 ANP 4.91803
29 4GKY MAN 4.91803
30 2B1N LYS ALA SER VAL GLY 4.91803
31 2XVF FAD 4.91803
32 3CGB FAD 5.7377
33 2XVE FAD 5.7377
34 1R18 SAH 5.7377
35 1VPE ANP 5.7377
36 5GSN NAP 5.7377
37 5GSN MMZ 5.7377
38 5GSN FAD 5.7377
39 2R14 FMN 5.7377
40 2R14 TXD 5.7377
41 5L4S NAP 6.55738
42 5L4S 6KX 6.55738
43 1OFD FMN 6.55738
44 5YLT SFG 6.55738
45 5NNA BZM 6.55738
46 1WPQ NAD 6.55738
47 2OFD NGA 7.04225
48 4D42 W0I 7.37705
49 4D42 NAP 7.37705
50 1T3Q FAD 7.37705
51 4UX9 ANP 7.37705
52 5WS9 AMP 7.37705
53 2RGO FAD 7.37705
54 5Z20 NAI 8.19672
55 5DEX 5E0 8.19672
56 2VPQ ANP 8.19672
57 3QWI CUE 8.19672
58 3QWI NAP 8.19672
59 1YKF NAP 9.01639
60 1M5B BN1 9.01639
61 4PLG NAI 9.01639
62 4PLG OXM 9.01639
63 2A92 NAI 9.01639
64 2NU8 COA 9.01639
65 1MDZ PLP 9.01639
66 1MDZ DCS 9.01639
67 4POO SAM 9.01639
68 3AB1 FAD 9.83607
69 2Q6B HR2 9.83607
70 1V97 FAD 9.83607
71 4DQ2 BTX 10.6557
72 3GF4 UPG 10.6557
73 6CEP OXM 10.6557
74 6CEP NAD 10.6557
75 3OEN GLU 10.6557
76 1O94 ADP 10.6557
77 3GF4 FAD 10.6557
78 1ZK4 AC0 10.6557
79 3B6R ADP 10.6557
80 1G55 SAH 10.6557
81 6DIO NAD 11.4754
82 2Q4W FAD 11.4754
83 5GZ6 7C3 11.4754
84 5GZ6 NDP 11.4754
85 4L8V NAP 11.4754
86 5X8G S0N 12.2951
87 3OZ2 FAD 12.2951
88 5G5G FAD 12.2951
89 4HDO GNP 13.1148
90 4PLT OXM 13.9344
91 4PLT NAI 13.9344
92 4BG4 ADP 13.9344
93 1FIQ FAD 13.9344
94 5ERG SAM 13.9344
95 3NRZ FAD 13.9344
96 3HDY FDA 15.5738
97 5L3S GNP 15.5738
98 3O26 NDP 17.2131
99 5OC1 FAD 17.2131
100 1KGQ SCO 17.2131
101 1KGQ NPI 17.2131
102 1FNZ A2G 19.6721
103 3ZEI AWH 19.6721
104 5FPE 3TR 19.6721
105 5W3K 9TY 19.6721
106 5W3K NDP 19.6721
107 3QDW A2G 21.3115
108 3QDV A2G 21.3115
Pocket No.: 3; Query (leader) PDB : 2NUO; Ligand: BGC; Similar sites found with APoc: 119
This union binding pocket(no: 3) in the query (biounit: 2nuo.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 5ZBL AMP None
2 3O61 GDD None
3 2B4D COA None
4 3CMC NAD None
5 2HNK SAH 0.83682
6 4YMH SAH 1.63934
7 1O0S NAI 1.63934
8 3RFV 15L 2.45902
9 2O4C NAD 2.45902
10 1CT9 GLN 2.45902
11 4JWF SAH 3.27869
12 4JWH SAH 3.27869
13 1PN0 FAD 3.27869
14 1PN0 IPH 3.27869
15 5I39 FAD 3.27869
16 2PT9 2MH 3.27869
17 2PT9 S4M 3.27869
18 1Q1R FAD 3.27869
19 3LL5 ATP 3.27869
20 1YKJ PHB 4.09836
21 1YKJ FAD 4.09836
22 2DKH FAD 4.09836
23 2I0K FAD 4.09836
24 3V1Y NAD 4.09836
25 3ITJ FAD 4.09836
26 4YKG NAD 4.09836
27 5I3B HQE 4.09836
28 4GN8 ASO 4.91803
29 1QO8 FAD 4.91803
30 4HA6 FAD 4.91803
31 2ZPA ACO 4.91803
32 3B1J NAD 4.91803
33 1M7Y PPG 4.91803
34 5E1M PRO PRO LYS ARG ILE ALA 4.91803
35 5E1M SAH 4.91803
36 1GAD NAD 4.91803
37 2D2I NAP 4.91803
38 4HA9 NDP 5.7377
39 4OOE FOM 5.7377
40 2F5T MAL 5.7377
41 5ZBC FAD 5.7377
42 1UXG NAD 5.7377
43 1UXG FUM 5.7377
44 2O3Z AI7 5.7377
45 1PHP ADP 5.7377
46 5YJI 8WO 5.7377
47 5YJI SAH 5.7377
48 5WKC FAD 5.7377
49 3E8N ATP 5.7377
50 3E8N VRA 5.7377
51 4MO4 ACP 5.7377
52 4EI7 GDP 5.7377
53 2D3N GLC GLC GLC 5.7377
54 2YVF NAD 6.55738
55 2YVF FAD 6.55738
56 3QFA FAD 6.55738
57 5NUE NAD 6.55738
58 1GUZ NAD 6.55738
59 1GV0 NAD 6.55738
60 5NUF NAD 6.55738
61 4O0L NDP 6.55738
62 4A59 AMP 6.55738
63 1YQS BSA 6.55738
64 4J36 FAD 6.98795
65 2B4R AES 7.37705
66 2B4R NAD 7.37705
67 1RVV INI 7.37705
68 3LU1 NAD 7.37705
69 4JDR FAD 7.37705
70 1RRM APR 7.37705
71 4IXW IXW 7.37705
72 1E3W NAD 7.37705
73 6C4M NAP 8.19672
74 4EXS X8Z 8.19672
75 2VYN NAD 8.19672
76 1GPM CIT 8.19672
77 5ZZ6 ADP 8.19672
78 3H9E NAD 8.19672
79 3D2M COA 9.01639
80 5TUK FAD 9.01639
81 2QV6 GTP 9.01639
82 3Q9T FAY 9.83607
83 5X20 NAD 9.83607
84 1B8U NAD 10.3343
85 3GDH MGP 10.6557
86 3CIF G3H 10.6557
87 1NAA 6FA 11.4754
88 1NAA ABL 11.4754
89 4Z0H NAD 11.4754
90 4TXI FAD 11.4754
91 3I53 SAH 11.4754
92 5LOG SAH 12.2951
93 3DUW SAH 12.2951
94 3GFB NAD 12.2951
95 1C7R PA5 12.2951
96 2Q1W NAD 12.2951
97 1KYZ FER 13.1148
98 2GAG FAD 13.1148
99 1KOJ PAN 13.1148
100 1IK4 PGH 13.1148
101 4AT0 FAD 13.9344
102 5ODQ FAD 13.9344
103 1U7T NAD 13.9344
104 5FJN BE2 13.9344
105 5FJN FAD 13.9344
106 4CM9 NAP 13.9344
107 3WGT FAD 14.7541
108 3WGT QSC 14.7541
109 2IID FAD 14.7541
110 2IID PHE 14.7541
111 4MOP 2H5 15.5738
112 1FP2 SAH 16.3934
113 1RP7 TZD 17.2131
114 3SSO SAH 18.0328
115 2R2N KYN 19.6721
116 5HSA FAS 23.7705
117 1RM0 D6P 27.0492
118 1RM0 NAI 27.0492
119 4UP3 FAD 27.0492
Pocket No.: 4; Query (leader) PDB : 2NUO; Ligand: BGC; Similar sites found with APoc: 45
This union binding pocket(no: 4) in the query (biounit: 2nuo.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4WOP CTP None
2 2B4B COA None
3 2JAP NDP 1.63934
4 4I2D APC 1.63934
5 2HXW FLC 2.45902
6 4MIG G3F 3.27869
7 5JIC N7E 3.27869
8 5JIC ADP 3.27869
9 1Z82 NDP 4.09836
10 1W5F G2P 4.09836
11 2DT9 THR 4.09836
12 4EMI NAD 4.91803
13 4Z0G 5GP 4.91803
14 1H6C SIN 4.91803
15 1H6C NDP 4.91803
16 3RS8 APR 4.91803
17 3AB4 THR 5.7377
18 6B3V 7DQ 5.7377
19 6B3V ANP 5.7377
20 5Y77 FAD 5.7377
21 1TUU ADP 5.7377
22 6GNC FAD 7.37705
23 2C5A GDC 7.37705
24 2C5A NAD 7.37705
25 3LAD FAD 7.37705
26 1CER NAD 7.37705
27 5EOW FAD 7.37705
28 1B63 ANP 8.19672
29 4M52 M52 8.19672
30 5T2U NAP 9.01639
31 2Y6Q FAD 9.01639
32 2Y6Q I7T 9.01639
33 1MJH ATP 9.01639
34 1DZK PRZ 9.01639
35 4YSX FAD 9.83607
36 1B8U OAA 10.3343
37 4Z24 FAD 11.4754
38 1OYB FMN 11.4754
39 1OYB HBA 11.4754
40 1GET NAP 11.4754
41 1GET FAD 11.4754
42 1DSS NAD 13.1148
43 4D7E FAD 13.1148
44 6ALW BMJ 18.0328
45 1KPH SAH 27.0492
Pocket No.: 5; Query (leader) PDB : 2NUO; Ligand: BGC; Similar sites found with APoc: 68
This union binding pocket(no: 5) in the query (biounit: 2nuo.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 3BGD PM6 None
2 3BGD SAH None
3 1VL0 NAI None
4 2ZIF SAM 3.27869
5 4I42 1HA 3.27869
6 1SQF SAM 4.09836
7 3NYC IAR 4.09836
8 3NYC FAD 4.09836
9 4RLQ 3SK 4.09836
10 1SB8 NAD 4.91803
11 1SB8 UD2 4.91803
12 3GDN HBX 4.91803
13 3ICR FAD 4.91803
14 3ICS FAD 4.91803
15 4J7U YTZ 4.91803
16 4J7U NAP 4.91803
17 1N7G GDR 4.91803
18 1N7G NDP 4.91803
19 5YJF SAH 4.91803
20 5YJF 8WO 4.91803
21 4EIL NDP 4.91803
22 3KO8 NAD 5.7377
23 1OAA OAA 5.7377
24 3TO7 COA 5.7377
25 4U36 TNR 5.7377
26 1RPN NDP 6.26866
27 6FP4 FAD 6.55738
28 6FP4 E1T 6.55738
29 3AAQ ARU 6.55738
30 1V59 NAD 6.55738
31 5JE8 NAD 6.55738
32 1P9P SAH 6.55738
33 1N5D NDP 7.37705
34 1E6W NAD 7.37705
35 1BXG HCI 7.37705
36 1ON3 MCA 7.37705
37 1F8G NAD 7.37705
38 2YY7 NAD 8.19672
39 1XTP SAI 8.19672
40 4M52 FAD 8.19672
41 1YQZ FAD 9.83607
42 4ZRN UPG 9.83607
43 4ZRN NAD 9.83607
44 2FR1 NDP 9.83607
45 5OE4 3UK 10.6557
46 1PS9 FAD 11.4754
47 3LZW NAP 12.2951
48 3NT6 FAD 12.2951
49 1P77 ATR 13.1148
50 1C1D PHE 13.1148
51 4ONQ SFG 13.1148
52 5DHF GNP 13.1148
53 5UWJ GNP 13.1148
54 5DIF GNP 13.1148
55 1U7T TDT 13.9344
56 1PL6 NAD 13.9344
57 4I4Z 2NE 13.9344
58 5HJM MTA 14.7541
59 5MIT NAP 15.5738
60 5MIT FAD 15.5738
61 4IQY AR6 15.5738
62 1FP2 HMO 16.3934
63 2QA1 FAD 16.3934
64 2A2C NG1 19.6721
65 2A2C ADP 19.6721
66 1IY8 NAD 22.1311
67 1BXK NAD 31.1475
68 5Z75 NAD 37.7049
Pocket No.: 6; Query (leader) PDB : 2NUO; Ligand: BGC; Similar sites found with APoc: 26
This union binding pocket(no: 6) in the query (biounit: 2nuo.bio1) has 8 residues
No: Leader PDB Ligand Sequence Similarity
1 4RFM 3P6 None
2 4KYQ FLC None
3 4KCT PYR 1.63934
4 1I52 CTP 2.45902
5 5TTJ FAD 4.09836
6 3ICT FAD 4.91803
7 4D04 FAD 5.7377
8 4D04 NAP 5.7377
9 6C2Z P1T 5.7377
10 2E5V FAD 6.55738
11 4PU6 ASP 9.01639
12 1NLU IVA PHI TYB 9.01639
13 5GM9 CBK 9.01639
14 3KJS NAP 9.01639
15 1QL9 ZEN 9.01639
16 3PFD FDA 9.83607
17 1ZK4 NAP 10.6557
18 1MHW BP4 CYS DAR TYR PEA 11.9048
19 2GAG FOA 13.1148
20 3EWP APR 13.1148
21 2VZ0 NAP 13.9344
22 2VZ0 D64 13.9344
23 3HDY GDU 15.5738
24 3AXB PRO 15.5738
25 4L1F FAD 23.7705
26 2PEL LBT 24.5902
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