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Receptor
PDB id Resolution Class Description Source Keywords
2O1V 2.45 Å NON-ENZYME: OTHER STRUCTURE OF FULL LENGTH GRP94 WITH ADP BOUND CANIS LUPUS FAMILIARIS GRP94 HSP82 HSP90 HTPG CHAPERONE ADP GP96 ENDOPLASMIN
Ref.: STRUCTURES OF GRP94-NUCLEOTIDE COMPLEXES REVEAL MEC DIFFERENCES BETWEEN THE HSP90 CHAPERONES. MOL.CELL V. 28 41 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:301;
B:302;
Valid;
Valid;
none;
none;
Kd ~ 5 uM
427.201 C10 H15 N5 O10 P2 c1nc(...
MG A:755;
A:756;
B:755;
B:756;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2O1V 2.45 Å NON-ENZYME: OTHER STRUCTURE OF FULL LENGTH GRP94 WITH ADP BOUND CANIS LUPUS FAMILIARIS GRP94 HSP82 HSP90 HTPG CHAPERONE ADP GP96 ENDOPLASMIN
Ref.: STRUCTURES OF GRP94-NUCLEOTIDE COMPLEXES REVEAL MEC DIFFERENCES BETWEEN THE HSP90 CHAPERONES. MOL.CELL V. 28 41 2007
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2O1V Kd ~ 5 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 2O1U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2O1V Kd ~ 5 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 2O1U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 4IPE - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4IYN - ADP ALF n/a n/a
3 5Y3N ic50 = 0.079 uM 8MF C13 H9 Br Cl N5 O2 c1c(c(cc2c....
4 4J0B - ADP BEF n/a n/a
5 4IVG - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
6 2O1V Kd ~ 5 uM ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
7 2O1U - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2O1V; Ligand: ADP; Similar sites found with APoc: 108
This union binding pocket(no: 1) in the query (biounit: 2o1v.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5LIA 6XN 1.05105
2 1FCH TYR GLN SER LYS LEU 1.63043
3 5ICE 2H4 1.70455
4 5ICE SAH 1.70455
5 5J6A P46 1.75
6 1Q9I TEO 1.92644
7 1Q9I FAD 1.92644
8 2ZKJ ADP 2.03046
9 2EFX NFA 2.20386
10 3JZB 4HY 2.24719
11 6MPT C30 2.44755
12 1E7S NAP 2.49221
13 4D9M 0JO 2.51256
14 1S16 ANP 2.5641
15 4AMV F6R 2.62726
16 3ELW SAM 2.66667
17 4GYW UDP 2.7027
18 3P7N FMN 2.71318
19 4HY1 19X 2.82051
20 2ITM XUL 2.89256
21 4ZVI 4S4 2.91777
22 1KZN CBN 2.92683
23 1ZED PNP 3.09917
24 1QZR CDX 3.11005
25 1QZR ANP 3.11005
26 2WR1 NAG 3.14342
27 3G5D 1N1 3.14685
28 4URL XAM 3.20197
29 2HHP FLC 3.20755
30 4ZGM 32M 3.27869
31 3TDC 0EU 3.6036
32 1GKZ ADP 3.60825
33 3RDE OYP 3.66492
34 2XDQ MGX 3.7182
35 4B7X NAP 3.86905
36 1LL2 UPG 3.9039
37 6GBV FMN 4.10959
38 4WGF HX2 4.39024
39 1P9B IMO 4.52489
40 3TTZ 07N 4.54545
41 6CD1 PLS 4.61538
42 2C2A ADP 4.65116
43 4WAS COO 4.67033
44 4GCZ ADP 4.67532
45 4P8O 883 4.81283
46 1NF8 BOG 4.83092
47 4G31 0WH 5.01672
48 1N46 PFA 5.03876
49 3WYJ H78 5.13834
50 1S14 NOV 5.15464
51 4DE3 DN8 5.32319
52 1QF5 RPL 5.56845
53 1QF5 GDP 5.56845
54 4OIV XX9 5.75221
55 4CQE CQE 5.7554
56 4ZM4 PLP 5.81656
57 5XNC MTA 5.92992
58 1ZXM ANP 6
59 5G5W R8C 6.07143
60 5C2H 4XU 6.07735
61 2QE4 JJ3 6.45161
62 4GGL CJC 6.51163
63 6BQC LOP 6.52742
64 3BQD DAY 6.66667
65 3GZ9 D32 6.69145
66 3EHH ADP 6.88073
67 4P6X HCY 7.05882
68 1KIJ NOV 7.17949
69 1F06 2NP 7.1875
70 1F06 NDP 7.1875
71 5ZYN FAD 7.431
72 3D36 ADP 8.60656
73 6GL8 F3Q 8.72093
74 4BIX ADP 9.39597
75 1GU3 BGC BGC BGC BGC BGC 9.39597
76 4EMV 0R9 9.73451
77 4BAE RWX 9.7561
78 4B6C B5U 10.2041
79 5IDM ANP 10.6145
80 1WY7 SAH 10.628
81 4WUJ FMN 10.8844
82 3SFI 3SF 11.4407
83 3EHG ATP 11.7188
84 1ID0 ANP 11.8421
85 3FEI CTM 11.985
86 2PYU IMP 12.3288
87 1V0C KNC 12.3762
88 1V0C ACO 12.3762
89 1DTL BEP 12.4224
90 4HZ0 1AV 12.6761
91 1I58 ACP 12.6984
92 1I58 ADP 12.6984
93 4V1F BQ1 12.7907
94 3GWL FAD 14.1509
95 1Y8O ADP 14.8438
96 4QC6 30N 15.0838
97 1TH8 ADP 15.1724
98 1TID ATP 15.4412
99 1TO9 HMH 15.7692
100 4URN NOV 16.4444
101 5LWY OLB 16.8224
102 4PL9 ADP 16.9399
103 1B63 ANP 18.018
104 4OGQ 7PH 19.3548
105 1UPT GTP 23.3333
106 4EES FMN 23.4783
107 2HKJ RDC 28.5714
108 3VRV YSD 46.1538
Pocket No.: 2; Query (leader) PDB : 2O1V; Ligand: ADP; Similar sites found with APoc: 294
This union binding pocket(no: 2) in the query (biounit: 2o1v.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5MT9 ARG None
2 5MT9 SRO None
3 1UVC STE None
4 5OLZ T4E 1.38249
5 6C1R EFD 1.4218
6 4BQH 9VU 1.45719
7 1OLM VTQ 1.48883
8 4LY9 1YY 1.72684
9 4LY9 S6P 1.72684
10 6BMS POV 1.75953
11 3VHZ L2P GLC MAN SGA 1.9084
12 5MWY YNU 1.96721
13 5L7G 6QE 1.96721
14 5HGZ ACO 2.05761
15 5GUD NDP 2.12314
16 5GUD 2IT 2.12314
17 4DXJ IPE 2.20994
18 4DXJ 0M9 2.20994
19 5EW9 5VC 2.21402
20 3LN0 52B 2.21465
21 2MAS PIR 2.2293
22 4Q0A 4OA 2.31788
23 5LGA 6VH 2.33333
24 1YOK P6L 2.34375
25 1GEG GLC 2.34375
26 2VL8 CTS 2.38095
27 4AMF ACP 2.38095
28 2VL8 UDP 2.38095
29 1TMX HGX 2.38908
30 3RS8 ALA TRP LEU PHE GLU ALA 2.39044
31 4ZVV GN0 2.40964
32 4ZVV NAD 2.40964
33 1UBY DMA 2.45232
34 5HH0 COA 2.5
35 5AE2 FAD 2.58359
36 6ESN BWE 2.62172
37 3P0K FAD 2.63158
38 3EWK FAD 2.64317
39 4WPF 3SN 2.65152
40 2FV5 541 2.68199
41 4IGH 1EA 2.68817
42 4IGH ORO 2.68817
43 4IGH FMN 2.68817
44 4RC8 STE 2.7027
45 3AAQ ARU 2.83286
46 2D5Z L35 2.83688
47 5CKS GAL 2.849
48 3W5N RAM 2.85285
49 4BXK 1IU 2.86169
50 2E2R 2OH 2.86885
51 2P4Y C03 2.88809
52 1DMH LIO 2.89389
53 1TV5 N8E 2.93454
54 5NTP 98E 2.94118
55 5TWO 7MV 2.94118
56 3G9E RO7 2.95203
57 3ETG GTP 2.99401
58 3ETG GLU 2.99401
59 2GWH PCI 3.02013
60 3LDW ZOL 3.0303
61 4Z87 GDP 3.04762
62 5IXK 6EW 3.07018
63 5HCV 60R 3.11284
64 3HR1 PF9 3.15789
65 1M13 HYF 3.16456
66 4ORM FMN 3.2419
67 4ORM 2V6 3.2419
68 4ORM ORO 3.2419
69 5NKB 8ZT 3.26797
70 3NB0 G6P 3.3033
71 5W8Q BU4 3.33333
72 5G57 6M5 3.33333
73 3D9F FAD 3.42466
74 3D9F N6C 3.42466
75 1DKF BMS 3.43348
76 3RWP ABQ 3.53698
77 4ELG 52J 3.61446
78 5FVJ ACO 3.61446
79 4ELG 52I 3.61446
80 6DIO CIT 3.7296
81 4MRP GSH 3.74593
82 3JRX S1A 3.74787
83 2BCG GER 3.75276
84 3G5N PB2 3.78151
85 3G4G D71 3.80048
86 1SJD NPG 3.80435
87 2NNQ T4B 3.81679
88 2Z7I 742 3.82353
89 4KVX ACO 3.84615
90 5V3Y 5V8 3.84615
91 4IA6 EIC 3.89171
92 4POJ 2VP 3.8961
93 1UUO BRF 3.9039
94 1UUO ORO 3.9039
95 1UUO FMN 3.9039
96 2GMH UQ5 3.93836
97 3H0A D30 3.94737
98 1W96 S1A 3.97112
99 4I4B NAD 3.97196
100 4I4B 1CV 3.97196
101 5XJ7 87O 3.9801
102 5AZC PGT 4
103 1LQA NDP 4.04624
104 2Q2Y ADP 4.08719
105 2Q2Y MKR 4.08719
106 4NB5 2JT 4.09357
107 2WPX ACO 4.12979
108 1ZIN AP5 4.14747
109 1ATL 0QI 4.45545
110 4H6U ACO 4.5
111 3UA1 08Y 4.51745
112 6ARJ BW4 4.58453
113 6ARJ SAH 4.58453
114 3TGE TGE 4.60123
115 3KP6 SAL 4.63576
116 3WR7 COA 4.70588
117 1OYJ GSH 4.7619
118 1U1I NAD 4.84694
119 4C2X NHW 4.87805
120 4UTG ANP 4.91329
121 1PZO CBT 4.94297
122 2GSQ GBI 4.9505
123 3QKD HI0 4.97238
124 5KOR GDP 4.9904
125 2J07 HDF 5
126 2J07 FAD 5
127 3SQP 3J8 5.02092
128 4BTB PRO PRO PRO PRO PRO PRO PRO PRO PRO 5.02092
129 1P0H COA 5.03145
130 1P0H ACO 5.03145
131 1UDY CS8 5.05051
132 3NWQ 2NC 5.05051
133 1LRI CLR 5.10204
134 3HKW IX6 5.16351
135 4R3L COA 5.20231
136 3FAL LO2 5.26316
137 3GF2 SAL 5.47945
138 1ZPD CIT 5.6338
139 5XWV 8H6 5.64516
140 4O4K 2PK 5.65476
141 5TO8 7FM 5.67376
142 5EK3 5PK 5.7072
143 5UGW GSH 5.71429
144 3WDM ADN 5.74713
145 3BZ3 YAM 5.7971
146 2I0G I0G 5.83658
147 5HZ9 5M8 5.92593
148 1OUK 084 6.01093
149 5B4B LP5 6.04839
150 3G08 FEE 6.06061
151 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 6.06061
152 5FKP 6UL 6.06061
153 1NHZ 486 6.07143
154 5M37 9SZ 6.08696
155 4XPL ACO 6.13497
156 5BYK OAQ 6.17761
157 5BYK A3P 6.17761
158 1SR7 MOF 6.17761
159 4UA3 COA 6.18557
160 2QZO KN1 6.20155
161 2EVL GAL SPH EIC 6.2201
162 1U3R 338 6.22407
163 2YJD YJD 6.25
164 5FBN 5WF 6.27306
165 5OLK DTP 6.27907
166 4RJK TPP 6.30473
167 4AVB ACO 6.30631
168 3KFC 61X 6.32411
169 5AAV GW5 6.34921
170 4TV1 36M 6.3745
171 3UUD EST 6.3745
172 3W54 RNB 6.38298
173 6BA2 7KM 6.44068
174 2BHW NEX 6.46552
175 4DK7 0KS 6.47773
176 1M2Z DEX 6.61479
177 1N83 CLR 6.66667
178 1TIQ COA 6.66667
179 1GHE ACO 6.77966
180 4KOT CE3 6.79012
181 5OHJ 9VE 6.88836
182 6GH1 ARG LEU PRO ALA LYS ALA PRO LEU LEU 7
183 1F0X FAD 7.00525
184 5N5U 7N8 7.00637
185 5LX9 OLB 7.04225
186 5WL1 D3D 7.07071
187 5U98 1KX 7.07071
188 5W7B MYR 7.0922
189 4X6F 3XU 7.11744
190 5OCA 9QZ 7.14286
191 5BQI 4UL 7.14286
192 5BQI GSH 7.14286
193 4RW3 PLM 7.28477
194 4RW3 TDA 7.28477
195 2CIX CEJ 7.35786
196 1YKI FMN 7.37327
197 1YKI NFZ 7.37327
198 4TWP AXI 7.38007
199 3B5J 12D 7.40741
200 5IM3 DTP 7.50751
201 1R6N 434 7.58294
202 3E70 GDP 7.62195
203 2VAT COA 7.65766
204 5W7D PX8 7.80781
205 6CB2 OLC 7.84983
206 2Q1H AS4 8
207 4I67 G G G RPC 8.04598
208 5UC1 486 8.10811
209 3EYK EYK 8.13953
210 3GWT 066 8.2153
211 2WPB ZZI 8.22368
212 2YFB SIN 8.52713
213 4DV8 0LX 8.55513
214 5NM7 GLY 8.64662
215 1CMC SAM 8.65385
216 1XVB 3BR 8.74036
217 1N1G BCP 8.74317
218 4Y30 49L 8.83191
219 5UC9 MYR 8.84956
220 3QLM PLM 8.87097
221 3OKI OKI 9.01288
222 5EEH P9P 9.04255
223 4HBM 0Y7 9.16667
224 4F4S EFO 9.21053
225 3ZJ0 ACO 9.2233
226 5IKH 6BW 9.27273
227 5IVX ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 9.27835
228 1JUV NDP 9.32642
229 5TIV A3P 9.48617
230 3MG9 GHP 3MY 3FG GHP GHP OMY 3FG 9.86395
231 1H9G COA MYR 9.87654
232 1JQ9 PHE LEU SER TYR LYS 9.91736
233 2D5X L35 9.92908
234 2Y69 CHD 10
235 5XDT MB3 10.0649
236 3KMZ EQO 10.1504
237 4M4Q 21A 10.3734
238 1T0S BML 10.4651
239 6CHP F0Y 10.559
240 3E7O 35F 10.8333
241 4CVZ TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 11.2245
242 3SP6 IL2 11.2281
243 1T8U UAP SGN IDS SGN 11.3971
244 5LJ0 6XX 11.5385
245 1MT1 AG2 11.5385
246 3KDU NKS 11.5523
247 2P1C GG3 11.7949
248 2BJ4 OHT 11.9048
249 4R57 ACO 11.9318
250 4E2J MOF 12.4
251 3QUZ QUV 12.4481
252 3GN8 DEX 12.4498
253 5UFS 1TA 12.5
254 2ZFZ ARG 12.6582
255 2VBQ BSJ 12.7273
256 5V03 658 12.7451
257 1NTV ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 13.1579
258 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 13.2653
259 3N7S 3N7 13.5417
260 5ZCO CHD 14.2857
261 5Z84 CHD 14.2857
262 5W97 CHD 14.2857
263 5H94 LYS MET ASN THR GLN PHE THR ALA VAL 14.2857
264 2DYS PGV 14.2857
265 2DYR PGV 14.2857
266 5ZCO TGL 14.2857
267 5ZCO PGV 14.2857
268 5Z84 PGV 14.2857
269 4LSJ LSJ 14.3411
270 5F1R 42O 14.346
271 2CNT COA 14.375
272 1NU4 MLA 14.433
273 1LTI GAL 14.5631
274 3RMK BML 16.6667
275 5C1M CLR 16.8
276 5IH1 6BQ 17.5497
277 5IH1 GDP 17.5497
278 3WCA FPS 18.0822
279 1LN1 DLP 18.2243
280 4OGQ 2WM 19.3548
281 4OGQ 1O2 19.3548
282 1N13 AG2 20.354
283 2QQC AG2 20.5357
284 5M36 9SZ 21.0526
285 5CHR 4NC 22.6277
286 1BII ARG GLY PRO GLY ARG ALA PHE VAL THR ILE 22.6891
287 3KPE TM3 38.4615
288 3IPQ 965 40
289 1FM9 570 40
290 2NPA MMB 40
291 3BEJ MUF 40
292 1RDT 570 43.4783
293 2HFP NSI 47.619
294 1K7L 544 47.619
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