Receptor
PDB id Resolution Class Description Source Keywords
2P1O 1.9 Å NON-ENZYME: OTHER MECHANISM OF AUXIN PERCEPTION BY THE TIR1 UBIQUITIN LIGASE ARABIDOPSIS THALIANA F-BOX LEUCINE RICH REPEAT SIGNALING PROTEIN
Ref.: MECHANISM OF AUXIN PERCEPTION BY THE TIR1 UBIQUITIN LIGASE NATURE V. 446 640 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
IHP B:701;
Valid;
none;
submit data
660.035 C6 H18 O24 P6 C1(C(...
NLA B:801;
Valid;
none;
submit data
186.207 C12 H10 O2 c1ccc...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2P1O 1.9 Å NON-ENZYME: OTHER MECHANISM OF AUXIN PERCEPTION BY THE TIR1 UBIQUITIN LIGASE ARABIDOPSIS THALIANA F-BOX LEUCINE RICH REPEAT SIGNALING PROTEIN
Ref.: MECHANISM OF AUXIN PERCEPTION BY THE TIR1 UBIQUITIN LIGASE NATURE V. 446 640 2007
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2P1O - NLA C12 H10 O2 c1ccc2c(c1....
2 2P1N - IHP C6 H18 O24 P6 C1(C(C(C(C....
3 2P1Q - IHP C6 H18 O24 P6 C1(C(C(C(C....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2P1O - NLA C12 H10 O2 c1ccc2c(c1....
2 2P1N - IHP C6 H18 O24 P6 C1(C(C(C(C....
3 2P1Q - IHP C6 H18 O24 P6 C1(C(C(C(C....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2P1O - NLA C12 H10 O2 c1ccc2c(c1....
2 2P1N - IHP C6 H18 O24 P6 C1(C(C(C(C....
3 2P1Q - IHP C6 H18 O24 P6 C1(C(C(C(C....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: IHP; Similar ligands found: 23
No: Ligand ECFP6 Tc MDL keys Tc
1 IHP 1 1
2 I6P 1 1
3 5IP 0.652174 1
4 5MY 0.652174 1
5 IP5 0.652174 1
6 I5P 0.652174 1
7 I0P 0.608696 0.965517
8 I8P 0.6 0.965517
9 2YN 0.6 0.965517
10 I7P 0.6 0.965517
11 I4P 0.571429 1
12 5A2 0.555556 0.8
13 4WZ 0.555556 0.8
14 5A3 0.555556 0.8
15 2IP 0.545455 0.933333
16 4IP 0.538462 0.965517
17 ITP 0.52 0.933333
18 IP2 0.5 0.933333
19 I3S 0.481481 0.933333
20 I3P 0.481481 0.933333
21 I4D 0.48 0.9
22 0EJ 0.46875 0.823529
23 4WY 0.454545 0.8
Ligand no: 2; Ligand: NLA; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 NLA 1 1
2 3N4 0.413793 0.708333
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2P1O; Ligand: IHP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2p1o.bio1) has 31 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2P1O; Ligand: NLA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2p1o.bio1) has 31 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2P1O; Ligand: IHP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2p1o.bio2) has 31 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2P1O; Ligand: IHP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2p1o.bio2) has 31 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 2P1O; Ligand: NLA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 2p1o.bio2) has 31 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 2P1O; Ligand: NLA; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 2p1o.bio2) has 31 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback