Receptor
PDB id Resolution Class Description Source Keywords
2Q09 1.97 Å EC: 3.5.2.7 CRYSTAL STRUCTURE OF IMIDAZOLONEPROPIONASE FROM ENVIRONMENTA WITH BOUND INHIBITOR 3-(2,5-DIOXO-IMIDAZOLIDIN-4-YL)-PROPIO UNIDENTIFIED 9252H NYSGXRC IMIDAZOLONEPROPIONASE 3-(2 5-DIOXO-IMIDAZO4YL)-PROPIONIC ACID PSI-2 COMMUNITY STRUCTURAL GENOMICS STRUCTURE INITIATIVE NEW YORK SGX RESEARCH CENTER FOR STRUGENOMICS HYDROLASE
Ref.: A COMMON CATALYTIC MECHANISM FOR PROTEINS OF THE HU FAMILY. BIOCHEMISTRY V. 47 5608 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DI6 A:600;
Valid;
none;
submit data
172.139 C6 H8 N2 O4 C(CC(...
FE A:500;
Part of Protein;
none;
submit data
55.845 Fe [Fe+3...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2Q09 1.97 Å EC: 3.5.2.7 CRYSTAL STRUCTURE OF IMIDAZOLONEPROPIONASE FROM ENVIRONMENTA WITH BOUND INHIBITOR 3-(2,5-DIOXO-IMIDAZOLIDIN-4-YL)-PROPIO UNIDENTIFIED 9252H NYSGXRC IMIDAZOLONEPROPIONASE 3-(2 5-DIOXO-IMIDAZO4YL)-PROPIONIC ACID PSI-2 COMMUNITY STRUCTURAL GENOMICS STRUCTURE INITIATIVE NEW YORK SGX RESEARCH CENTER FOR STRUGENOMICS HYDROLASE
Ref.: A COMMON CATALYTIC MECHANISM FOR PROTEINS OF THE HU FAMILY. BIOCHEMISTRY V. 47 5608 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2Q09 - DI6 C6 H8 N2 O4 C(CC(=O)O)....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 2Q09 - DI6 C6 H8 N2 O4 C(CC(=O)O)....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2Q09 - DI6 C6 H8 N2 O4 C(CC(=O)O)....
2 2PUZ - NIG C6 H10 N2 O4 [H]/N=CN[C....
3 2G3F - IZC C5 H6 N2 O2 C1N=CC(=N1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DI6; Similar ligands found: 2
No: Ligand ECFP6 Tc MDL keys Tc
1 DI6 1 1
2 5HY 0.540541 0.93617
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2Q09; Ligand: DI6; Similar sites found: 615
This union binding pocket(no: 1) in the query (biounit: 2q09.bio2) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1UWZ THU 0.005666 0.40236 None
2 3ICC NAP 0.01974 0.40157 None
3 3ZZS TRP 0.02305 0.4019 0.480769
4 2ZSC BTN 0.004303 0.40485 0.70922
5 1LCP PLU 0.005036 0.41877 0.961538
6 1T10 F6P 0.005559 0.40347 1.20192
7 3K5X P8D 0.001396 0.41881 1.25
8 1LTH NAD 0.04835 0.40073 1.25392
9 1Z45 NAD 0.001074 0.45281 1.44231
10 3WE0 FAD 0.003511 0.4457 1.44231
11 3UH0 TSB 0.001169 0.44166 1.44231
12 1ZK7 FAD 0.009881 0.42749 1.44231
13 1OWB NAD 0.00443 0.42744 1.44231
14 1ZFJ IMP 0.02252 0.40979 1.44231
15 2BJK NAD 0.04417 0.40289 1.44231
16 3S7O LBV 0.001458 0.44859 1.45773
17 1DLJ NAI 0.02879 0.40968 1.49254
18 2R42 FPS 0.001715 0.42925 1.51899
19 4QN6 LNV 0.001153 0.4606 1.53453
20 2XK9 XK9 0.0008451 0.46272 1.5528
21 1R6W 164 0.002651 0.4154 1.5528
22 3C1O NAP 0.01237 0.40106 1.55763
23 4Q3R XA2 0.01104 0.40458 1.55844
24 1V7R CIT 0.03216 0.40012 1.6129
25 3MAG 3MA 0.01319 0.41978 1.62866
26 1GR0 NAD 0.01352 0.43754 1.63488
27 2BKA NDP 0.01067 0.40931 1.65289
28 2ZJF BSU 0.003661 0.40269 1.65746
29 1V9N NDP 0.00378 0.4323 1.66667
30 1H82 FAD 0.005699 0.44616 1.68269
31 1H82 GZZ 0.008613 0.44001 1.68269
32 2Q1S NAI 0.005898 0.43571 1.68269
33 2WQP WQP 0.002557 0.43254 1.68269
34 2QF7 COA 0.005268 0.40141 1.68269
35 3MCT SAH 0.007417 0.40537 1.6835
36 1S8F GDP 0.006686 0.41511 1.69492
37 4M5P MLA 0.0002748 0.50436 1.7199
38 4M5P 23W 0.01348 0.40477 1.7199
39 1I2B USQ 0.005524 0.4453 1.73267
40 1I2B NAD 0.005524 0.4453 1.73267
41 1I2B UPG 0.005524 0.4453 1.73267
42 3BL6 FMC 0.00294 0.41785 1.73913
43 1EYQ NAR 0.002583 0.40578 1.8018
44 3SIX GDP 0.00146 0.42073 1.81818
45 1B8U NAD 0.00752 0.40513 1.82371
46 3ZPG 5GP 0.005669 0.42975 1.83246
47 4NM5 ADP 0.001264 0.43847 1.85676
48 1NW5 SAM 0.008614 0.40097 1.88088
49 4EKV BTN 0.01242 0.41137 1.88679
50 3AHC TPP 0.002569 0.4368 1.92308
51 3ULK NDP 0.002847 0.42407 1.92308
52 1KBI PYR 0.00421 0.4235 1.92308
53 1KBI FMN 0.00421 0.4235 1.92308
54 2XVF FAD 0.008471 0.42291 1.92308
55 2Q28 ADP 0.00278 0.4208 1.92308
56 1H6W SER LEU ASN TYR ILE ILE LYS VAL LYS GLU 0.02165 0.41494 1.92308
57 2XVE FAD 0.0323 0.414 1.92308
58 3ZEI AWH 0.002762 0.43407 1.93548
59 4F2Q QUS 0.004968 0.40241 1.93798
60 1KBJ FMN 0.00507 0.41865 1.94175
61 3HY3 10F 0.004256 0.41862 1.97044
62 4W97 UCA 0.007426 0.41025 2
63 2EWM NAD 0.003493 0.43248 2.00803
64 1IM8 SAI 0.006718 0.40712 2.04918
65 3B20 NAD 0.01077 0.40502 2.0649
66 1R6D DAU 0.01143 0.42942 2.07715
67 1R6D NAD 0.03507 0.40786 2.07715
68 1RYI FAD 0.005834 0.43592 2.09424
69 1RYI GOA 0.007999 0.42983 2.09424
70 1CKN GTP 0.003598 0.40029 2.12121
71 1V35 NAI 0.003551 0.44354 2.12766
72 4CKU P2F 0.004733 0.44352 2.12766
73 4PO2 ASN ARG LEU LEU LEU THR GLY 0.005144 0.41684 2.12766
74 4DEM YS4 0.0336 0.42174 2.13333
75 4IVG ANP 0.003156 0.45314 2.16346
76 4IOK ADP 0.001307 0.4447 2.16346
77 3FC4 EDO 0.006587 0.44107 2.16346
78 3LGG CFE 0.003727 0.43106 2.16346
79 4OE4 NAD 0.004244 0.42823 2.16346
80 4G87 UD1 0.009802 0.42807 2.16346
81 1P9B IMO 0.004107 0.42088 2.16346
82 4IOK XPO 0.005853 0.41293 2.16346
83 3A2Q ACA ACA 0.004163 0.40978 2.16346
84 4JRB PGT 0.00303 0.40841 2.16346
85 1P9B GDP 0.00648 0.40212 2.16346
86 1D3V ABH 0.007878 0.41069 2.16718
87 2B4Q NAP 0.009224 0.41328 2.17391
88 2BLE 5GP 0.006665 0.44446 2.17984
89 2PT9 2MH 0.007015 0.42319 2.18069
90 1YHM AHD 0.0002996 0.42505 2.20994
91 2C4I BTN 0.006394 0.40029 2.21402
92 2G86 UMP 0.01431 0.42271 2.21519
93 3I51 45C 0.002668 0.41056 2.22222
94 1KTC NGA 0.003949 0.40395 2.22222
95 3RFV NAI 0.001258 0.44695 2.24719
96 2GDZ NAD 0.007902 0.41613 2.24719
97 3TXO 07U 0.00294 0.41134 2.26629
98 4B4D FAD 0.006558 0.40755 2.29008
99 1VJO PLP 0.004923 0.40478 2.29008
100 3TKA SAM 0.0005653 0.45074 2.30548
101 1R37 NAD 0.008191 0.42029 2.30548
102 3CH5 GDP 0.002666 0.41057 2.31481
103 3GE7 AFQ 0.01187 0.41222 2.33161
104 1OLS TDP 0.002114 0.45644 2.33918
105 1Z44 NPO 0.002062 0.47119 2.36686
106 1RZM E4P 0.001593 0.43955 2.36686
107 1UJ2 ADP 0.003423 0.42574 2.38095
108 1UJ2 C5P 0.01016 0.40609 2.38095
109 1OMZ UD2 0.01514 0.4175 2.38908
110 1Q3Q ANP 0.004776 0.44968 2.40385
111 1H6C SIN 0.002494 0.44822 2.40385
112 1H6C NDP 0.002281 0.44772 2.40385
113 2AMV BIN 0.004943 0.44435 2.40385
114 3WO0 ALA 0.00323 0.44002 2.40385
115 3WO0 ADP 0.00323 0.44002 2.40385
116 3QV9 QV7 0.000935 0.43512 2.40385
117 4MP8 MLI 0.004623 0.43437 2.40385
118 4MP8 NAD 0.004623 0.43437 2.40385
119 4KCF FMN 0.001191 0.42416 2.40385
120 1XOC VAL ASP SER LYS ASN THR SER SER TRP 0.01325 0.41736 2.40385
121 4KCF AKM 0.006416 0.41129 2.40385
122 1FP1 HCC 0.003766 0.41354 2.41935
123 1A27 NAP 0.004498 0.4265 2.42215
124 1A27 EST 0.002386 0.4172 2.42215
125 4DQ2 BTX 0.01744 0.40027 2.43902
126 2WK1 SAH 0.005389 0.41101 2.48227
127 3GJB AKG 0.001968 0.41028 2.50784
128 3MPI GRA 0.005965 0.44303 2.51889
129 3K37 BCZ 0.01651 0.43554 2.51889
130 2GQS C2R 0.009824 0.41057 2.53165
131 3PVT 3HC 0.005906 0.42974 2.57235
132 4HZX G39 0.01303 0.41672 2.57732
133 4BG1 IVL 0.002716 0.42309 2.58398
134 4BG1 OGA 0.002716 0.42309 2.58398
135 1RYD NDP 0.009533 0.42068 2.58398
136 3M0J OAF 0.001194 0.45228 2.60586
137 3S6T OAN 0.0005319 0.44531 2.64423
138 3NYQ MCA 0.00282 0.43773 2.64423
139 4O8A FAD 0.003158 0.43434 2.64423
140 1TIW TFB 0.005641 0.43166 2.64423
141 1TIW FAD 0.005641 0.43166 2.64423
142 2HGS ADP 0.001916 0.43109 2.64423
143 2C31 ADP 0.02156 0.42686 2.64423
144 2C31 TZD 0.02214 0.42686 2.64423
145 1YBH P22 0.005717 0.42338 2.64423
146 3ZY6 GFB 0.002749 0.42289 2.64423
147 1E2S CSN 0.002148 0.41668 2.64423
148 1K97 ASP 0.04588 0.4152 2.64423
149 1K97 CIR 0.04588 0.4152 2.64423
150 1YBH FAD 0.01453 0.41464 2.64423
151 1T0I FMN 0.003962 0.41266 2.64423
152 2HGS GSH 0.005388 0.40103 2.64423
153 1I36 NAP 0.004214 0.4188 2.65152
154 1OIK C26 0.0007034 0.43813 2.65781
155 2ZI8 SDT 0.005806 0.42047 2.66667
156 1KOL NAD 0.001949 0.44953 2.76382
157 1Q6O LG6 0.001192 0.42909 2.77778
158 4HGP KDO 0.01794 0.40663 2.77778
159 1PL6 572 0.01566 0.40702 2.80899
160 1PL6 NAD 0.01101 0.40004 2.80899
161 2RHW C0E 0.005631 0.44921 2.82686
162 1G0N PHH 0.008793 0.42616 2.82686
163 1G0N NDP 0.008802 0.42321 2.82686
164 2B82 ADN 0.0002964 0.46211 2.8436
165 3VPD ANP 0.003073 0.42092 2.84698
166 4W6Z 8ID 0.01161 0.4159 2.88184
167 4AQL TXC 0.002234 0.44639 2.88462
168 1Z4V DAN 0.000346 0.44499 2.88462
169 4FWE FAD 0.005318 0.4377 2.88462
170 1VJT NAD 0.002633 0.42175 2.88462
171 4J7H TRH 0.00311 0.41883 2.88462
172 1FA2 DOM 0.006767 0.41767 2.88462
173 2GSD NAD 0.01064 0.41649 2.88462
174 4MZ7 DGT 0.01396 0.40564 2.88462
175 3BK2 U5P 0.003879 0.40424 2.88462
176 2AQJ TRP 0.04889 0.40374 2.88462
177 4MZ7 DTP 0.01583 0.40331 2.88462
178 2OI2 DP6 0.00461 0.40133 2.88462
179 3H22 B53 0.003977 0.40131 2.88462
180 1NF8 ISC 0.00154 0.41983 2.89855
181 1GV0 NAD 0.002844 0.43492 2.90323
182 4GQB 0XU 0.02824 0.41149 2.90698
183 2R14 FMN 0.000475 0.46302 2.91777
184 3CL7 HYN 0.006112 0.41375 2.92208
185 1TU3 GNP 0.003842 0.42365 2.92398
186 2HEK GDP 0.001913 0.41354 2.96496
187 1E5F PLP 0.001651 0.42351 2.9703
188 3Q3C NAD 0.02028 0.41807 3.01003
189 1C0I FAD 0.004759 0.44167 3.0303
190 1C0I BE2 0.004759 0.44167 3.0303
191 4I71 AGV 0.001574 0.42872 3.0303
192 3SCH TB6 0.0009513 0.40028 3.0303
193 1NNU TCT 0.009661 0.44766 3.05677
194 1NNU NAD 0.009661 0.44766 3.05677
195 3DAG FEG 0.008775 0.40874 3.07263
196 3MD0 GDP 0.003302 0.40171 3.09859
197 2FFC U5P 0.006227 0.40479 3.11615
198 2XCG XCG 0.00464 0.42593 3.125
199 2V7T SAH 0.04131 0.42011 3.125
200 2CFU 1DB 0.004772 0.41316 3.125
201 2HGZ PBF 0.006532 0.41255 3.125
202 4RJK PYR 0.01218 0.4068 3.125
203 3KJI ADP 0.003425 0.411 3.14961
204 3HF3 FMN 0.007019 0.40805 3.15186
205 4OHB 5HM 0.002945 0.41359 3.15789
206 1V2G OCA 0.003008 0.40853 3.15789
207 4O1M NAD 0.0006088 0.46323 3.1746
208 1NUS APC 0.01567 0.41414 3.1746
209 1DR1 NAP 0.01473 0.41242 3.1746
210 1DR1 HBI 0.01473 0.41242 3.1746
211 3U5S FAD 0.00784 0.40439 3.1746
212 1NUS NMN 0.03235 0.40355 3.1746
213 2VAR ANP 0.003453 0.41886 3.19489
214 2VAR AMP 0.002885 0.40667 3.19489
215 3O55 FAD 0.005598 0.41686 3.2
216 1Q0H FOM 0.00626 0.43635 3.20197
217 1Q0H NDP 0.007172 0.43542 3.20197
218 1E4E ADP 0.001766 0.42672 3.207
219 1E4E PHY 0.004144 0.40773 3.207
220 1Q11 TYE 0.003766 0.40476 3.22581
221 4A8T PAO 0.02268 0.42117 3.24484
222 3I0O SMI 0.004653 0.40663 3.24484
223 3QVL 5HY 0.0339 0.40013 3.26531
224 3FXU TSU 0.001563 0.43821 3.27869
225 4TMK T5A 0.02816 0.43511 3.28639
226 1I0Z OXM 0.005304 0.43114 3.3033
227 1T8U UAP SGN IDS SGN 0.00808 0.42484 3.30882
228 4UOH ADP 0.0008871 0.42346 3.31126
229 1WUR 8DG 0.0008031 0.44649 3.36538
230 2IXB A2G 0.00264 0.44606 3.36538
231 2YPO PHE 0.005373 0.42323 3.36538
232 3LPF Z77 0.004496 0.42231 3.36538
233 2DDH HXD 0.004287 0.41505 3.36538
234 4KQL 1SG 0.03137 0.41459 3.36538
235 2ZX7 ZX7 0.009269 0.41382 3.36538
236 2QA1 FAD 0.01429 0.41092 3.36538
237 2IXB NAD 0.01775 0.40239 3.36538
238 1XHL NDP 0.009151 0.41589 3.367
239 3E5H GNP 0.002112 0.43281 3.37079
240 3P0K FAD 0.005361 0.41284 3.38346
241 1WNG SAH 0.00213 0.42546 3.39623
242 3GWT 066 0.006338 0.42147 3.39943
243 2DTX BMA 0.002268 0.45002 3.40909
244 1M5B BN1 0.004777 0.44967 3.42205
245 3P3N AKG 0.003757 0.4165 3.4384
246 1QY1 PRZ 0.000343 0.45953 3.44828
247 2AE2 PTO 0.002047 0.45303 3.46154
248 2AE2 NAP 0.002047 0.45303 3.46154
249 3IU9 T07 0.002099 0.46676 3.47222
250 2C2A ADP 0.001408 0.42851 3.48837
251 1XP8 AGS 0.02494 0.40863 3.55191
252 3FC2 IBI 0.01336 0.40644 3.58209
253 2H6B 3C4 0.0187 0.42111 3.6
254 1DSS NAD 0.001497 0.44064 3.6036
255 4KXV TDP DX5 0.003377 0.44139 3.60577
256 4CCO OGA 0.0007267 0.43295 3.60577
257 1SB8 UD2 0.01511 0.42391 3.60577
258 1SB8 NAD 0.0165 0.41913 3.60577
259 3IO3 ADP 0.006772 0.40332 3.60577
260 2NP9 YE1 0.01807 0.40322 3.60577
261 1JQI CAA 0.001229 0.44251 3.60825
262 1JQI FAD 0.004756 0.43274 3.60825
263 1VQ2 DDN 0.007011 0.40076 3.62694
264 1LYX PGA 0.0005937 0.43853 3.62903
265 2EFJ SAH 0.001054 0.4335 3.64583
266 1DJ9 KAM 0.01246 0.40093 3.64583
267 1LDM NAD 0.0251 0.42033 3.64742
268 3W54 RNB 0.003061 0.41065 3.64742
269 2E2R 2OH 0.004592 0.43111 3.68852
270 4IAE 1DX 0.004219 0.44703 3.7037
271 1XVA SAM 0.002408 0.42332 3.76712
272 1TDF FAD 0.004811 0.44234 3.79747
273 1TDF NAP 0.01012 0.44234 3.79747
274 1GSA ADP 0.006334 0.43784 3.79747
275 2R40 20E 0.006767 0.41192 3.80228
276 2P2V CSF 0.003234 0.45266 3.81944
277 4I9A NCN 0.003788 0.42829 3.81944
278 1N1G BCP 0.008414 0.4209 3.82514
279 1L2T ATP 0.01037 0.4027 3.82979
280 4AT0 FAD 0.002657 0.45476 3.84615
281 1H9A NAP 0.005282 0.42849 3.84615
282 1QPB TPP 0.003593 0.42638 3.84615
283 4IXW IXW 0.0007985 0.4252 3.84615
284 4ARF IP8 GLY PRO ALA 0.001847 0.42159 3.84615
285 4C6F DOR 0.001236 0.42085 3.84615
286 4C6F NCD 0.001236 0.42085 3.84615
287 1LVL FAD 0.01383 0.41924 3.84615
288 3QP4 HL0 0.003175 0.4123 3.84615
289 2NCD ADP 0.003542 0.41147 3.84615
290 3FED BIX 0.004915 0.40691 3.84615
291 1LC8 33P 0.0108 0.4064 3.84615
292 4P87 4NP 0.01128 0.4056 3.84615
293 3CBG SAH 0.005835 0.40394 3.84615
294 3DX5 DHB 0.003538 0.40326 3.84615
295 4LWA Q13 0.02742 0.40246 3.85675
296 2PWY SAH 0.002426 0.42865 3.87597
297 2Q8M AMP 0.0006422 0.43457 3.91566
298 2OWZ F6P 0.008825 0.42417 3.91566
299 2YVF FAD 0.009102 0.4389 3.92157
300 2YVF NAD 0.01037 0.43694 3.92157
301 4KQI NIO 0.001074 0.45423 3.93258
302 4KQI RBZ 0.001074 0.45423 3.93258
303 3WBF API 0.003202 0.43663 3.93443
304 3WBF NAP 0.01066 0.40933 3.93443
305 1G6O ADP 0.01132 0.40413 3.93939
306 3L0E G58 0.002812 0.43082 3.95257
307 1ZK4 AC0 0.002647 0.47325 3.98406
308 1ZK4 NAP 0.002647 0.47325 3.98406
309 3D3H M4O 0.004371 0.40682 4
310 4BAS GNP 0.008816 0.40232 4.0201
311 4CZG ADP 0.04159 0.40348 4.02299
312 2IYG FMN 0.0002049 0.42888 4.03226
313 1YRO UDP 0.01625 0.40158 4.06504
314 1C3V NDP 0.003824 0.43081 4.08163
315 4A3R CIT 0.001832 0.4495 4.08654
316 1V7W NAG 0.0002979 0.44751 4.08654
317 1V7W NDG 0.0002979 0.44751 4.08654
318 2C7G ODP 0.00664 0.44166 4.08654
319 2XDQ MGX 0.006326 0.42746 4.08654
320 2NVK FAD 0.01138 0.42121 4.08654
321 2C7G FAD 0.04136 0.40586 4.08654
322 4C12 ADP 0.04185 0.40363 4.08654
323 3D2Y AH0 ALA FGA LYS 0.007646 0.40121 4.08654
324 3PMD 11A 0.004124 0.4007 4.08654
325 3CXO 3LR 0.001361 0.44701 4.09639
326 3T2W BTN 0.0003042 0.44425 4.09836
327 1HDR NAD 0.005415 0.44174 4.09836
328 4KS1 2H8 0.01093 0.42379 4.10256
329 2YBQ SAH 0.002995 0.4195 4.10959
330 1SSQ CYS 0.01593 0.41861 4.11985
331 2WUF KEM 0.01073 0.40209 4.12371
332 2RDT FMN 0.01423 0.42654 4.13437
333 2RDT 2RD 0.0414 0.4004 4.13437
334 3B1F NAD 0.004712 0.41513 4.13793
335 2HMT NAI 0.01613 0.41958 4.16667
336 3DCM SAM 0.005381 0.40923 4.16667
337 2H8Z FMN 0.00891 0.41262 4.17827
338 2H8Z 8CM 0.00891 0.41262 4.17827
339 2QCX PF1 0.00246 0.41795 4.18251
340 4PLG NAI 0.01029 0.41923 4.19162
341 4PLG OXM 0.01029 0.41923 4.19162
342 1G7V PAI 0.01497 0.41408 4.22535
343 1YS4 NAP 0.007754 0.40628 4.23729
344 3MB5 SAM 0.004335 0.44692 4.31373
345 2PTZ PAH 0.0001486 0.46476 4.32692
346 4HA6 FAD 0.001314 0.46462 4.32692
347 1F8F NAD 0.01086 0.43192 4.32692
348 1L3I SAH 0.004 0.42443 4.32692
349 4K5S PM0 0.02744 0.40989 4.32692
350 2RGH FAD 0.02031 0.40915 4.32692
351 4K5S FAD 0.01731 0.40515 4.32692
352 3BW2 FMN 0.0005394 0.46545 4.33604
353 2YJ0 420 0.005847 0.44492 4.34783
354 1HEX NAD 0.01426 0.40268 4.34783
355 1JA9 NDP 0.01996 0.42732 4.37956
356 1JA9 PYQ 0.01331 0.40525 4.37956
357 3FS8 ACO 0.01472 0.43992 4.3956
358 4LIT AKG 0.001391 0.40429 4.4226
359 4C0X AQN 0.007915 0.41736 4.4335
360 4C0X FMN 0.006107 0.41676 4.4335
361 3I6B KDO 0.002539 0.40029 4.44444
362 4N02 FNR 0.01494 0.42413 4.48179
363 1KDK DHT 0.001548 0.43487 4.51977
364 1GAD NAD 0.0008515 0.45245 4.54545
365 1YB5 NAP 0.0006974 0.4663 4.5584
366 2PYU IMP 0.0001311 0.44066 4.56621
367 4QDC ASD 0.005866 0.41821 4.56731
368 4QDF 30Q 0.01075 0.40717 4.56731
369 1R5A GTS 0.0008601 0.42397 4.58716
370 4JK3 NAD 0.01126 0.40832 4.6332
371 3R35 4CO 0.001263 0.45124 4.63576
372 2X61 CH 0.0177 0.41086 4.65116
373 2X61 NGA GAL SIA 0.04865 0.40321 4.65116
374 1YOE RIB 0.003216 0.40214 4.65839
375 2OZE AGS 0.002881 0.4182 4.69799
376 3K3K A8S 0.003933 0.41472 4.73934
377 4NVP 7CH 0.02217 0.40263 4.78469
378 2J8Z NAP 0.0116 0.40777 4.80226
379 3T31 FAD 0.0076 0.43899 4.80769
380 2VJJ RAM GLC GAL NAG NAG GLC 0.008036 0.43442 4.80769
381 4C0C WVH 0.00706 0.43314 4.80769
382 3T31 DCQ 0.01133 0.43249 4.80769
383 3F3E LEU 0.006973 0.4266 4.80769
384 4NES UDP 0.001327 0.42953 4.81283
385 1H65 GDP 0.004558 0.41396 4.81482
386 3PJU C2E 0.009999 0.4078 4.81928
387 3LZW FAD 0.01994 0.40763 4.81928
388 1TH8 ADP 0.001939 0.41331 4.82759
389 2DUA OXL 0.007803 0.4027 4.82759
390 1NZY BCA 0.003231 0.42978 4.83271
391 2VBQ BSJ 0.008774 0.419 4.84848
392 1BGQ RDC 0.001511 0.44207 4.88889
393 1BUC CAA 0.004117 0.42084 4.96084
394 1A8R GTP 0.0009454 0.43968 4.97738
395 3P7I P7I 0.003108 0.40806 4.98442
396 3L02 CP 0.008907 0.41639 5.01393
397 3L02 SN0 0.008907 0.41639 5.01393
398 3MBG FAD 0.0009098 0.44961 5.03597
399 3JYN NDP 0.005254 0.42741 5.04808
400 3HU3 AGS 0.02897 0.41621 5.04808
401 3HPF GAE 0.0098 0.41803 5.11509
402 1UXG NAD 0.02678 0.40199 5.17799
403 1UXG FUM 0.02678 0.40199 5.17799
404 1I7L ATP 0.01089 0.40183 5.17799
405 2A0W DIH 0.0121 0.41241 5.19031
406 2QQF A1R 0.003243 0.42671 5.19481
407 2OD9 A1R NCA 0.006612 0.41941 5.19481
408 1Y9Q MED 0.0003263 0.46151 5.20833
409 1POC GEL 0.004129 0.40992 5.22388
410 2VEZ G6P 0.007658 0.41671 5.26316
411 2VEZ ACO 0.007491 0.4158 5.26316
412 3GEG NAD 0.01515 0.40157 5.26316
413 3W2W ATP 0.00328 0.40708 5.2795
414 2IMP NAI 0.005508 0.45818 5.28846
415 2AEB ABH 0.00711 0.41254 5.28846
416 3BAZ NAP 0.007812 0.41084 5.28846
417 1WVG CXY 0.006284 0.41002 5.28846
418 1N20 3AG 0.01686 0.41001 5.28846
419 1WVG APR 0.009824 0.40669 5.28846
420 3T1A 5MA 0.006523 0.40398 5.28846
421 1T57 FMN 0.003242 0.42176 5.33981
422 2OYS FMN 0.001615 0.43226 5.3719
423 2ZB3 NDP 0.003811 0.42818 5.38244
424 1SG4 CO8 0.001146 0.44707 5.38462
425 3I28 34N 0.01053 0.4271 5.40541
426 1OAA OAA 0.0261 0.40691 5.40541
427 1XE7 GUN 0.004637 0.43395 5.41872
428 1GS5 NLG 0.001355 0.45262 5.42636
429 1GS5 ANP 0.001355 0.45262 5.42636
430 2Q97 ATP 0.004573 0.41566 5.42636
431 4JP3 CIT 0.0008355 0.43013 5.43933
432 3TCT 3MI 0.0105 0.43111 5.51181
433 2DKH FAD 0.0007997 0.46243 5.52885
434 1EP2 ORO 0.001884 0.44775 5.52885
435 2NX1 PEP 0.00239 0.43527 5.52885
436 1EP2 FMN 0.005021 0.42175 5.52885
437 2DKH 3HB 0.01161 0.41893 5.52885
438 3KMZ EQO 0.005529 0.41856 5.52885
439 2NX1 RP5 0.006957 0.4158 5.52885
440 1X54 4AD 0.01312 0.4 5.52885
441 2EJU SAH 0.004287 0.41129 5.55556
442 1YAG ATP 0.004861 0.41625 5.6
443 2J7T 274 0.002374 0.43684 5.62914
444 1BTN I3P 0.01005 0.43584 5.66038
445 4PB2 5UD 0.002886 0.41818 5.66038
446 3PNL ADP 0.00294 0.4235 5.6872
447 2YC5 6BC 0.0002505 0.48677 5.70175
448 2HW1 ANP 0.0004818 0.45356 5.7047
449 3ZZL TRP 0.02994 0.40077 5.71429
450 3D3W NAP 0.008275 0.41654 5.7377
451 1PR9 NAP 0.01793 0.40449 5.7377
452 3OND ADN 0.003564 0.44905 5.76923
453 3OND NAD 0.003564 0.44905 5.76923
454 1FIQ SAL 0.002554 0.43957 5.76923
455 4CS4 AXZ 0.006699 0.43325 5.76923
456 1FIQ MTE 0.003407 0.43161 5.76923
457 4CS4 ANP 0.006858 0.42691 5.76923
458 1FIQ FAD 0.008524 0.41954 5.76923
459 3UR0 SVR 0.01653 0.41665 5.76923
460 3CEV ARG 0.003167 0.4024 5.76923
461 1JCM 137 0.002366 0.4369 5.79151
462 1SOW NAD 0.0088 0.41662 5.79268
463 3CQD ATP 0.009817 0.42012 5.82524
464 1IYE PGU 0.006944 0.41978 5.82524
465 2WGC SIA GAL BGC 0.02121 0.41751 5.84795
466 1Y75 NAG 0.0004124 0.43612 5.9322
467 2V5E SCR 0.01508 0.41683 5.94059
468 3ZS7 ATP 0.0001815 0.47284 6.00962
469 2NXW TPP 0.001991 0.44418 6.00962
470 4OJ8 AKG 0.0009745 0.43915 6.00962
471 3Q9T FAY 0.005134 0.43345 6.00962
472 4R33 TRP 0.006201 0.42432 6.00962
473 4R33 SAH 0.006201 0.42432 6.00962
474 3IB8 AMP 0.003074 0.41058 6.00962
475 4OJ8 2TQ 0.008685 0.40426 6.00962
476 9LDB NAD 0.0009173 0.45714 6.0241
477 9LDT NAD 0.0009801 0.45592 6.0241
478 1P4C FMN 0.02172 0.42444 6.05263
479 1AUX AGS 0.005265 0.40572 6.10932
480 3PXP MYR 0.001135 0.43222 6.16438
481 1UJ5 5RP 0.002099 0.41461 6.1674
482 1V2X SAM 0.0004238 0.45372 6.18557
483 1D6H COA 0.01825 0.41388 6.20155
484 1UOU CMU 0.004848 0.40282 6.25
485 4UAL 3FV 0.006713 0.40151 6.25
486 3ZOD FMN 0.006823 0.41475 6.28272
487 3ZOD HQE 0.006823 0.41475 6.28272
488 1CL2 PPG 0.007832 0.40264 6.32911
489 1RP0 AHZ 0.0413 0.41238 6.33803
490 2F59 INI 0.001309 0.43192 6.36943
491 3N5O GSH 0.004723 0.4096 6.38298
492 3RO7 TDR 0.01467 0.40217 6.41509
493 4NTD FAD 0.004768 0.43485 6.47059
494 1M7Y PPG 0.002728 0.43569 6.49038
495 1QF5 GDP 0.007448 0.43468 6.49038
496 1QF5 RPL 0.007448 0.43468 6.49038
497 3O03 NAP 0.003397 0.42739 6.49038
498 1ML4 PAL 0.0008061 0.44919 6.49351
499 2ALG DAO 0.002004 0.42845 6.52174
500 2ALG HP6 0.002004 0.42845 6.52174
501 3S2Y FMN 0.000837 0.4397 6.53266
502 1C1L GAL BGC 0.003129 0.42661 6.56934
503 1U7Z PMT 0.007558 0.42064 6.63717
504 4IS0 1R4 0.006617 0.4091 6.639
505 1JIL 485 0.002471 0.42287 6.73077
506 1C7S CBS 0.003493 0.40601 6.73077
507 3NKS ACJ 0.004948 0.40469 6.73077
508 3OIG IMJ 0.0114 0.41296 6.76692
509 3SFI 3SF 0.01406 0.41622 6.77966
510 3S9K CIT 0.04915 0.40066 6.77966
511 1V1A KDG 0.006763 0.40612 6.79612
512 1F5F DHT 0.00002655 0.49702 6.82927
513 4INB 1F6 0.001332 0.43367 6.84932
514 3UEC ALA ARG TPO LYS 0.008648 0.4071 6.84932
515 1VDC FAD 0.001116 0.47164 6.90691
516 4USQ FAD 0.01246 0.41243 6.92521
517 2GGH NLQ 0.001246 0.45672 6.93333
518 1R89 CTP 0.001733 0.42268 6.97115
519 2V6O FAD 0.03805 0.41619 6.97115
520 2YCJ C2F 0.004361 0.40463 6.97115
521 1L1Q 9DA 0.004495 0.41238 6.98925
522 3EWC MCF 0.01641 0.41364 7.00809
523 4G1V FAD 0.01166 0.40637 7.01754
524 3ZRR PXG 0.005795 0.40793 7.03125
525 3IOI 1GW 0.002648 0.4389 7.04698
526 2QDT I38 0.00317 0.41233 7.0632
527 1TOI HCI 0.004761 0.42411 7.07071
528 1FL2 FAD 0.007573 0.42807 7.09677
529 4UBP HAE 0.001926 0.4282 7.14286
530 1SS4 CIT 0.004324 0.43886 7.18954
531 1SS4 GSH 0.01463 0.43482 7.18954
532 1H9G COA MYR 0.001886 0.43805 7.21154
533 1JYQ MAZ PTR PTM ASN 0.03795 0.40419 7.29167
534 1ULE GLA GAL NAG 0.01333 0.40499 7.33333
535 2QXX TTP 0.0192 0.40535 7.36842
536 3TN7 NJP 0.005856 0.42293 7.393
537 4TSK NDP 0.03328 0.4109 7.42857
538 3TA2 AKG 0.005921 0.42012 7.45192
539 4AF0 MOA 0.004988 0.4174 7.45192
540 1ECC PCP 0.005409 0.41434 7.45192
541 4AF0 IMP 0.02287 0.41272 7.45192
542 3V91 UPG 0.008369 0.4324 7.56014
543 3OZG SSI 0.005883 0.40172 7.6
544 1R27 MGD 0.0009248 0.46354 7.69231
545 1GPJ CIT 0.0004397 0.41017 7.69231
546 2VPR TDC 0.0005189 0.44334 7.72947
547 2BNE U5P 0.004533 0.43076 7.88382
548 2PTR 2SA 0.0005908 0.45907 7.93269
549 1YGC 905 0.008201 0.40183 7.93651
550 1FDJ 2FP 0.001318 0.42244 7.98898
551 1X1T NAD 0.01129 0.44011 8.07692
552 4DVE BTN 0.0004349 0.43828 8.08081
553 1XLI GLT 0.002399 0.442 8.12183
554 3EW2 BTN 0.0006562 0.42844 8.14815
555 4EPL JAI 0.002085 0.41952 8.17308
556 1QS0 TDP 0.0007127 0.44462 8.28402
557 3SVL FMN 0.003694 0.41185 8.41346
558 2Z9C DTC 0.01115 0.4044 8.5
559 1MQ0 BRD 0.001078 0.4284 8.57143
560 1Y8O ADP 0.00135 0.41937 8.59375
561 4OYA 1VE 0.0475 0.42042 8.65385
562 1PFK ADP 0.001457 0.42566 8.75
563 1A69 FMB 0.03089 0.41491 8.82353
564 2Q1A 2KT 0.0003677 0.41404 9.13461
565 3UXL CFI 0.001369 0.46176 9.13838
566 1NX4 AKG 0.0005156 0.41718 9.15751
567 4NAT 2W5 0.004709 0.43402 9.375
568 4NAT ADP 0.02452 0.42832 9.375
569 2J07 HDF 0.01254 0.4253 9.52381
570 2J07 FAD 0.01254 0.4253 9.52381
571 5RHN 8BR 0.005907 0.40165 9.56522
572 3UIE ANP 0.0007421 0.42936 10
573 3HQJ COA 0.00639 0.40433 10
574 1UKW FAD 0.005472 0.43118 10.0264
575 4B8V NDG NAG NAG NAG 0.007122 0.41397 10.0877
576 2JL1 NAP 0.01071 0.40054 10.1045
577 1NVV GNP 0.003765 0.42401 10.241
578 1NVU GTP 0.01846 0.42136 10.241
579 4FR3 0V4 0.01855 0.42939 10.2564
580 2NLI FMN 0.02205 0.41495 10.3261
581 2NLI LAC 0.02205 0.41495 10.3261
582 1D09 PAL 0.02559 0.43603 10.4575
583 2GJ3 FAD 0.001113 0.44071 10.8333
584 3DG6 MUC 0.002117 0.41692 11.1717
585 3PFG TLO 0.007364 0.4286 11.4068
586 3PFG SAM 0.007364 0.4286 11.4068
587 4CO3 ATP 0.03213 0.40118 11.6071
588 1T0S BML 0.0002886 0.48154 11.6279
589 1UO5 PIH 0.01265 0.42946 11.7647
590 2HXT EHM 0.005459 0.4008 11.7788
591 3RF4 FUN 0.003487 0.40608 12.069
592 4L6C 0BT 0.00173 0.43289 12.3762
593 2JAR UMP 0.002199 0.4229 12.5
594 2D0V PQQ 0.007027 0.40454 12.5
595 2WCV FUC 0.002164 0.4087 12.8571
596 4QED NAP 0.01275 0.40731 13.3065
597 3WCS MAN NAG GAL 0.00296 0.40625 13.3858
598 3SJ7 NDP 0.003994 0.42732 13.4921
599 2Q2V NAD 0.001387 0.4522 13.7255
600 1E7S NAP 0.01837 0.40291 14.3302
601 4GYW UDP 0.01241 0.41022 14.6635
602 1NN5 ANP 0.006304 0.42029 15.3488
603 1NN5 2DT 0.006304 0.42029 15.3488
604 1P72 THM 0.001359 0.40964 15.8683
605 1Y52 BTN 0.02395 0.40687 15.873
606 1NHZ 486 0.002029 0.43007 16.0714
607 4LSJ LSJ 0.0002564 0.46466 16.2791
608 1V5F TPP 0.02667 0.44455 16.8269
609 1V5F FAD 0.02667 0.44455 16.8269
610 3F81 STT 0.008167 0.41482 16.9399
611 1EXB NDP 0.03329 0.41791 17.4757
612 3H86 AP5 0.02767 0.40781 19.7917
613 1F3F D4T 0.01731 0.42334 21.2903
614 1F3F D4D 0.00783 0.42334 21.2903
615 3NCQ ATP 0.002018 0.42833 22.6891
Pocket No.: 2; Query (leader) PDB : 2Q09; Ligand: DI6; Similar sites found: 5
This union binding pocket(no: 2) in the query (biounit: 2q09.bio1) has 15 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4RZB NFQ 0.00396 0.42221 2.16346
2 2XMY CDK 0.02582 0.43435 3.02013
3 2Q7D ANP 0.02642 0.40444 3.17919
4 4IKR PVP 0.0357 0.40266 6.07903
5 4CQB MLI 0.0002278 0.44939 7.56501
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