Receptor
PDB id Resolution Class Description Source Keywords
2QCS 2.2 Å EC: 2.7.11.11 A COMPLEX STRUCTURE BETWEEN THE CATALYTIC AND REGULATORY SUB PROTEIN KINASE A THAT REPRESENTS THE INHIBITED STATE MUS MUSCULUS CYCLIC ADENOSINE MONOPHOSPHATE CAMP-DEPENDENT PROTEIN KINASHOLOENZYME CYCLIC NUCLEOTIDE BINDING DOMAIN PROTEIN-PROTEINTERACTION CONFORMATIONAL CHANGE PROTEIN BINDING TRANSFTRANSFERASE INHIBITOR COMPLEX
Ref.: PKA-I HOLOENZYME STRUCTURE REVEALS A MECHANISM FOR CAMP-DEPENDENT ACTIVATION. CELL(CAMBRIDGE,MASS.) V. 130 1032 2007
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:412;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
ANP A:400;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
GOL A:407;
A:410;
B:408;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MN A:401;
A:402;
Part of Protein;
Part of Protein;
none;
none;
submit data
54.938 Mn [Mn+2...
SO4 A:403;
B:400;
B:401;
B:403;
B:404;
B:405;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
TAM A:406;
Invalid;
none;
submit data
163.215 C7 H17 N O3 C(CO)...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2QCS 2.2 Å EC: 2.7.11.11 A COMPLEX STRUCTURE BETWEEN THE CATALYTIC AND REGULATORY SUB PROTEIN KINASE A THAT REPRESENTS THE INHIBITED STATE MUS MUSCULUS CYCLIC ADENOSINE MONOPHOSPHATE CAMP-DEPENDENT PROTEIN KINASHOLOENZYME CYCLIC NUCLEOTIDE BINDING DOMAIN PROTEIN-PROTEINTERACTION CONFORMATIONAL CHANGE PROTEIN BINDING TRANSFTRANSFERASE INHIBITOR COMPLEX
Ref.: PKA-I HOLOENZYME STRUCTURE REVEALS A MECHANISM FOR CAMP-DEPENDENT ACTIVATION. CELL(CAMBRIDGE,MASS.) V. 130 1032 2007
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 9 families.
1 4X6R - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2QCS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 8 families.
1 4X6R - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2QCS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
50% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 4X6R - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
2 2QCS - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
3 3FHI - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2QCS; Ligand: ANP; Similar sites found: 396
This union binding pocket(no: 1) in the query (biounit: 2qcs.bio1) has 27 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3K5I ADP 0.003919 0.41792 2
2 3AKK ADP 0.0001461 0.43389 2.06186
3 4GLW 0XT 0.007889 0.43135 2.06186
4 3D91 REM 0.03905 0.41544 2.06186
5 3AVR OGA 0.03605 0.40238 2.06186
6 5EXK 5AD 0.01032 0.43004 2.4055
7 4CC6 L5Y 0.01011 0.42586 2.4055
8 3ETH ATP 0.002386 0.42376 2.74914
9 5LKC FUC GLA A2G 0.03078 0.40161 2.74914
10 4J25 OGA 0.03939 0.40092 3.05677
11 4PU5 ANP 0.000157 0.46975 3.09278
12 1IOW PHY 0.001029 0.43577 3.09278
13 2YW2 ATP 0.002532 0.42618 3.09278
14 5MW8 ATP 0.0000001941 0.55455 3.14286
15 4R78 AMP 0.000002218 0.61207 3.23625
16 1GU3 BGC BGC BGC BGC BGC 0.03295 0.40345 3.3557
17 3WXL ADP 0.002215 0.47407 3.43643
18 2CFM AMP 0.002442 0.45219 3.43643
19 2R0D 4IP 0.01922 0.41584 3.45821
20 1CKN GTP 0.03055 0.40119 3.63636
21 1Q1Y BB2 0.01108 0.41163 3.66492
22 3WVR AMP 0.0001375 0.502 3.71429
23 4ME6 ADP 0.01186 0.42655 3.71429
24 4LH7 1X8 0.003439 0.45087 3.71517
25 4U98 ACP 0.000779 0.46151 3.74449
26 1AUX AGS 0.0003017 0.47561 3.78007
27 1PK8 ATP 0.0005225 0.44053 3.78007
28 5KJW 53C 0.02618 0.41428 3.78007
29 4OUJ LBT 0.003272 0.44531 3.90879
30 3TDV GDP 0.00000004287 0.64991 3.92157
31 4OUC 5ID 0.00000000547 0.5507 4
32 1QY1 PRZ 0.004638 0.41144 4.02299
33 2Q7D ANP 0.001256 0.42199 4.04624
34 3I0O ADP 0.00006386 0.53073 4.12371
35 3UDZ ADP 0.0000003101 0.52395 4.12371
36 4AXD ANP 0.000001856 0.46851 4.12371
37 4UWH JXM 0.001834 0.44871 4.12371
38 5C1P ADP 0.0004524 0.48286 4.24837
39 5C1P DAL DAL 0.003409 0.40774 4.24837
40 5FS0 5JC 0.0273 0.40371 4.2654
41 1IA9 ANP 0.000001639 0.57135 4.28571
42 2VPQ ANP 0.0002486 0.43722 4.28571
43 4WOE ADP 0.01689 0.4219 4.28571
44 1TZD ADP 0.00006295 0.54628 4.36364
45 3X01 AMP 0.0007087 0.49263 4.46735
46 4XYM A12 0.0007912 0.45229 4.46735
47 4ZGP ADP 0.003914 0.42902 4.46735
48 5T96 79J 0.04046 0.40318 4.46735
49 1TMX BEZ 0.0288 0.40251 4.46735
50 4DFU QUE 0.01249 0.42569 4.65839
51 5KTI TRE 6X6 0.02601 0.40745 4.69799
52 4FE2 ADP 0.001663 0.45545 4.70588
53 4CS9 AMP 0.00589 0.4322 4.7619
54 4OYA 1VE 0.004814 0.43168 4.811
55 2R7K AMZ 0.005126 0.40075 4.811
56 5I35 ANP 0.000003848 0.56829 4.85714
57 2PYW ADP 0.000002919 0.5539 4.85714
58 4AZT LY2 0.001219 0.46716 4.85714
59 4AZW ATP 0.00003992 0.45871 4.85714
60 2IO8 ADP 0.0003021 0.45392 4.85714
61 1F52 ADP 0.005402 0.43063 4.85714
62 1W2D ADP 0.0005404 0.48471 4.90566
63 1W2D 4IP 0.001499 0.40946 4.90566
64 1GT4 UNA 0.005376 0.42262 5.03145
65 2NGR AF3 0.02567 0.4092 5.12821
66 4GYI ADP 0.000004563 0.57958 5.15464
67 1T3D CYS 0.01672 0.41711 5.19031
68 1TQP ATP 0.000003397 0.53381 5.31915
69 4OCJ NDG 0.000005596 0.45762 5.49828
70 3V4S ATP 0.004268 0.41298 5.49828
71 1E4E ADP 0.001447 0.44065 5.53936
72 2AUY NAG MAN MMA 0.02243 0.40049 5.55556
73 3KYF 5GP 5GP 0.02323 0.40341 5.62771
74 1SU2 ATP 0.00642 0.41538 5.66038
75 1YRO UDP 0.03276 0.40731 5.69106
76 3TY5 ATP 0.009808 0.42214 5.71429
77 3TY5 ADP 0.0182 0.40136 5.71429
78 1ZTH ADP 0.0000002574 0.64955 5.81395
79 1ZP9 ATP 0.0000003815 0.62304 5.81395
80 3RE4 TO1 0.000005218 0.58471 5.81395
81 5GZ9 ANP 0.000000002943 0.62079 5.84192
82 5IQD RIO 0.0000892 0.48345 5.84192
83 5IQD GNP 0.00008249 0.48345 5.84192
84 3BP1 GUN 0.03128 0.41587 5.86207
85 2GQR ADP 0.0002865 0.41035 5.90717
86 3VPD ANP 0.0006897 0.41771 6.04982
87 5TDF ADP 0.0005746 0.41816 6.17284
88 2QL9 CIT 0.009876 0.42994 6.18557
89 1S9A BEZ 0.0306 0.40114 6.22568
90 2AQX ATP 0.0003427 0.45968 6.22837
91 4RT1 C2E 0.009905 0.41029 6.25
92 4O1P ANP 0.00000006755 0.5394 6.28571
93 2PUL ACP 0.00002855 0.528 6.28571
94 5MRH Q9Z 0.0009859 0.47737 6.28571
95 1EHI ADP 0.001639 0.43825 6.28571
96 3DNT ATP 0.0003473 0.43754 6.28571
97 5LXT ACP 0.0004136 0.45218 6.29371
98 2FOI JPA 0.007131 0.42904 6.3197
99 1I7L ATP 0.0003699 0.45031 6.52921
100 2YRX AMP 0.00276 0.46126 6.57143
101 5HZX 2GE 0.02399 0.40271 6.81818
102 4OAV ACP 0.00000006107 0.6516 6.85714
103 1FHX 4IP 0.03385 0.40284 6.97674
104 3ORQ ADP 0.002637 0.42541 7.2165
105 3TM0 ANP 0.00007199 0.44242 7.22433
106 3TM0 B31 0.00007876 0.43612 7.22433
107 4IX4 ADP 0.000002348 0.49951 7.42857
108 4LO2 GAL BGC 0.006569 0.42973 7.43243
109 5C4L 4XR 0.000009163 0.51425 7.56014
110 5C4L SIS 0.00007455 0.47756 7.56014
111 4LRJ ANP 0.00000001049 0.68701 7.69231
112 1SN0 T44 0.01075 0.4161 7.69231
113 1OBD ATP 0.0001154 0.51161 7.84314
114 2QHV OC9 0.01848 0.41243 8.09524
115 2IF8 ADP 0.0000285 0.56374 8.24742
116 2XG5 EC5 0.01024 0.42656 8.25688
117 2XG5 EC2 0.01024 0.42656 8.25688
118 2VQD AP2 0.000377 0.46215 8.28571
119 5W2I ADP 0.00009082 0.47531 8.56031
120 5W2I I3P 0.00009082 0.47531 8.56031
121 4OCV ANP 0.00001106 0.53456 8.59107
122 2Z49 AMG 0.01077 0.43382 8.59107
123 3ZJX BOG 0.001615 0.47601 8.65052
124 4XMF HSM 0.0002232 0.52489 8.69565
125 2X3J ATP 0.009499 0.40116 8.85714
126 1DZK PRZ 0.01123 0.40776 8.9172
127 4ZS4 ATP 0.0000005104 0.59383 9.12052
128 5DYO FLU 0.01851 0.41941 9.17431
129 2QHS OCA 0.02424 0.40249 9.2827
130 5VZ0 ADP 0.00006237 0.51228 9.62199
131 5TT6 ATP 0.001434 0.43319 9.71429
132 3AI3 SOL 0.02824 0.40701 9.88593
133 3SAO DBH 0.02277 0.40807 10
134 3PDT ADP 0.000005922 0.56666 10.1818
135 3LJU IP9 0.007329 0.44368 10.2857
136 5KBE IPH 0.01703 0.41861 10.4803
137 2H92 C5P 0.01637 0.40719 10.5023
138 3TPV ADE 0.009807 0.40371 10.5714
139 3NOJ PYR 0.00552 0.43615 10.9244
140 5K2M ADP 0.0005339 0.43008 10.989
141 1GSA ADP 0.00001319 0.48672 10.9966
142 3VSV XYS 0.02905 0.40847 10.9966
143 5U98 1KX 0.01124 0.41269 11.1111
144 4NZF ARB 0.01979 0.41517 11.1429
145 2HGS ADP 0.0008032 0.4196 11.3402
146 3VPB ADP 0.00003807 0.4863 11.3475
147 3VPC ADP 0.000177 0.4719 11.3475
148 3Q60 ATP 0.0000001928 0.51653 11.4286
149 2VDJ HSE 0.011 0.42311 11.6279
150 3W0O HY0 0.000262 0.43278 11.6838
151 3W0O ADP 0.000262 0.43278 11.6838
152 3HAV ATP 0.0004848 0.43833 11.7057
153 2GQS ADP 0.0001978 0.48908 11.8143
154 2BKK ADP 0.00008634 0.4245 11.8343
155 5U7W ADE 0.01085 0.43209 12.3711
156 4O4F ATP 0.001292 0.42472 12.5
157 4O4F IHP 0.001576 0.4181 12.5
158 5CKW ANP 0.000001771 0.60799 12.8571
159 1XVB BHL BHL 0.0231 0.40113 13.5294
160 5DMZ ADP 0.000000000006714 0.82231 14
161 4OH4 ANP 0.00000001505 0.67051 14.4144
162 5LPZ ADP 0.00000001425 0.67158 14.759
163 5KO1 6UY 0.000002867 0.57421 15.1943
164 2QLU ADE 0.0000004988 0.6739 15.2866
165 3LQV ADE 0.00549 0.43058 15.3846
166 4IJP 1EH 0.00000009182 0.55138 15.4286
167 4I94 ANP 0.00000001925 0.67481 15.6667
168 2RIO ADP 0.0000000000759 0.78611 16
169 5LPB ADP 0.0000001208 0.66586 16.2162
170 3VY6 BGC BGC 0.02299 0.40101 16.3121
171 5BVE 4VG 0.00000004973 0.42781 17.4286
172 2CSN CKI 0.000000003099 0.64351 18.1818
173 4WW7 AMP 0.00001987 0.51237 18.7739
174 4CYI ATP 0.000002808 0.55463 18.8571
175 1LOB MMA 0.01729 0.41391 19.2308
176 4Y8D 49J 0.0000005645 0.5992 19.4118
177 3VHE 42Q 0.000002958 0.50107 19.7143
178 4YZC STU 0.00000001826 0.63387 20.5714
179 5C03 AGS 0.000003929 0.56102 21.345
180 4Y0X ADP 0.000001029 0.60264 22
181 5DZT AMP 0.001311 0.4786 22.2857
182 1M0S CIT 0.02266 0.40788 22.3744
183 2PZI AXX 0.00001556 0.55377 22.8571
184 4WOV 3SM 0.00009775 0.5151 23.0284
185 4Q5H ANP 0.00000009733 0.63378 23.6842
186 4JR7 GNP 0.000000000008859 0.81685 25.1429
187 3KP6 SAL 0.01056 0.41397 25.1656
188 3HMO STU 0.0000006493 0.60407 25.4386
189 4CRL C1I 0.00001337 0.46236 26.601
190 1Q8Y ADP 0.00000000009006 0.74994 26.8571
191 1Q8Y ADE 0.00000002126 0.71475 26.8571
192 4IDT T28 0.000000001066 0.73298 27.1429
193 3VRY B43 0.00004163 0.48474 27.1429
194 5N87 N66 0.000001004 0.4852 27.476
195 4BTK DTQ 0.0000005781 0.51022 27.5964
196 5MY8 RXZ 0.0000004653 0.56325 27.7143
197 4E93 GUI 0.0000002414 0.52677 27.7143
198 3C1X CKK 0.0001744 0.47218 27.7143
199 5UIU 8CG 0.00000002397 0.61596 27.8638
200 3UIM ANP 0.000000009325 0.67993 27.9141
201 4H3Q ANP 0.0000000005213 0.69865 28.2857
202 4H3P ANP 0.00000002684 0.65913 28.2857
203 5T8O 76Z 0.00000008429 0.62081 28.3668
204 4XH0 ADP 0.000002702 0.62263 28.5714
205 3PP0 03Q 0.0000004584 0.55779 28.6982
206 1U5R ATP 0.00000000702 0.69509 28.7356
207 4QTB 38Z 0.0000003643 0.54438 28.8571
208 3H9R TAK 0.000006124 0.58964 29.0909
209 3TTI KBI 0.00000001417 0.60688 29.1429
210 3KMW ATP 0.0003411 0.47812 29.1513
211 1VJY 460 0.000000008396 0.57623 29.3729
212 3GNI ATP 0.00000003496 0.63742 29.4286
213 4BKJ STI 0.003129 0.40924 29.5238
214 3LXN MI1 0.00000000008536 0.75095 29.5597
215 4UX9 ANP 0.00000000001117 0.78934 29.7143
216 2B9J ADP 0.0000000009547 0.73521 29.7143
217 2B9I ADP 0.000000001819 0.71209 29.7143
218 2H8H H8H 0.0000002053 0.6191 29.7143
219 2B9H ADP 0.00000000297 0.59442 29.7143
220 4NFN 2KC 0.00002359 0.53183 30.0971
221 2PVN P63 0.0000000001928 0.66477 30.1136
222 3E8N ATP 0.000000005492 0.50926 30.2053
223 3E8N VRA 0.000000005492 0.50926 30.2053
224 5HCY 60D 0.000002315 0.44604 30.2115
225 2B9F ADP 0.000000001813 0.71215 30.2857
226 5LXC 7AA 0.00000000007661 0.60829 30.2857
227 3OFM 4B0 0.0000001272 0.50286 30.2857
228 5EOB 5QQ 0.000002268 0.56865 30.4075
229 2WU6 DKI 0.00000005315 0.61474 30.5714
230 4D2S DYK 0.000001599 0.60164 30.6338
231 4KBA 1QM 0.00006825 0.46699 30.8157
232 5W4W 9WG 0.00004212 0.45488 30.8157
233 3PE2 E1B 0.0000001073 0.61583 30.8605
234 4CLI 5P8 0.000007449 0.53525 30.8869
235 5JGA 6KC 0.0000008623 0.5062 31.1111
236 4P5Z Q7M 0.00007115 0.4203 31.1429
237 3ALN ANP 0.000000001838 0.69302 31.1927
238 5X8I SQZ 0.0000000002859 0.74849 31.2139
239 4F9C 0SX 0.00000000006753 0.78847 31.4286
240 1CM8 ANP 0.000000007246 0.69446 31.4286
241 4NST ADP 0.00000003512 0.55162 31.4286
242 1OPK P16 0.0000383 0.45518 31.4286
243 3LXK MI1 0.000000003047 0.63184 31.4985
244 3NW7 LGV 0.00001779 0.52191 31.5961
245 5DBX ANP 0.00000000113 0.75429 31.7073
246 4IZY 1J2 0.00000004519 0.63257 31.7143
247 4GJ3 0XP 0.00000006876 0.55204 31.7881
248 5BYZ 4WE 0.000004417 0.49022 31.8966
249 4U44 3D9 0.00000002644 0.54914 31.9277
250 4E1Z 0MX 0.000000003113 0.66623 31.9588
251 1Y57 MPZ 0.000001235 0.55766 32
252 4LOO SB4 0.0000646 0.50593 32
253 5HVJ ANP 0.0000001768 0.68978 32.0635
254 3KRR DQX 0.000000007894 0.4344 32.2034
255 3KRL KRL 0.00001056 0.52407 32.2388
256 4YLL 4E3 0.00000006993 0.57134 32.2857
257 4Y93 746 0.00000513 0.52132 32.2857
258 3ORK AGS 0.000000005497 0.6408 32.4759
259 1K3A ACP 0.000001018 0.47682 32.7759
260 4AT3 LTI 0.00009385 0.44874 32.7759
261 4Y85 499 0.0000006149 0.60516 32.8313
262 4NM5 ADP 0.000000243 0.58716 32.8571
263 5TO8 7FM 0.00002493 0.42865 32.9787
264 2OO8 RAJ 0.003862 0.41483 33.123
265 5EFQ ADP 0.00000004789 0.64774 33.1412
266 3PTG 932 0.000002864 0.4524 33.1429
267 4WHZ 3NL 0.000003778 0.42083 33.1429
268 5AWM ANP 0.00000002378 0.70089 34
269 1O9U ADZ 0.0000004882 0.67116 34
270 3PLS ANP 0.00000001056 0.55317 34.2282
271 2JLD AG1 0.000000003177 0.58302 34.2857
272 3E7O 35F 0.0000979 0.43495 34.2857
273 4QMN DB8 0.000001358 0.48154 34.5161
274 3F7Z 34O 0.00000004168 0.65047 34.5714
275 3ZRM ZRM 0.0000004313 0.60449 34.5714
276 5AX9 4KT 0.00000001542 0.67003 34.7403
277 4AUA 4AU 0.0000002944 0.61997 34.8534
278 5NKB 8ZT 0.00005439 0.41014 34.9673
279 2XVD AS6 0.00002467 0.4933 35.0993
280 3H0L ADP 0.007733 0.43179 35.1064
281 4ASE AV9 0.00004179 0.4823 35.1275
282 4AU8 Z3R 0.00000007582 0.6759 35.1351
283 4YZN 4K5 0.0000000005359 0.69815 35.1916
284 4EWH T77 0.0000003908 0.55122 35.2727
285 5JFS 6K0 0.0000172 0.51588 35.3896
286 3DAK ANP 0.00000003589 0.67164 35.5172
287 4YMJ 4EJ 0.0000003599 0.6693 35.5263
288 2HK5 1BM 0.00001749 0.46963 35.5556
289 2BPM 529 0.0000002056 0.45549 35.5987
290 4XV1 904 0.000002719 0.53925 35.6164
291 2F57 23D 0.000001464 0.59539 35.7143
292 5HES 032 0.000002406 0.50297 35.8306
293 5H2U 1N1 0.0001306 0.49207 35.9551
294 3O0G 3O0 0.00000001388 0.54893 35.9589
295 1UNH IXM 0.00000004007 0.51577 35.9589
296 4G31 0WH 0.00005639 0.4358 36.1204
297 3GGF GVD 0.000000005063 0.71191 36.2126
298 5DA3 58V 0.000001338 0.61403 36.2264
299 2A19 ANP 0.0000004633 0.63689 36.2676
300 3GC8 B45 0.000006413 0.53329 36.2857
301 4X7Q 3YR 0.000000001476 0.7162 36.5385
302 5M06 ADP 0.0000006454 0.61223 36.5942
303 4CFU 2WC 0.00000002729 0.67727 36.6337
304 5HX8 66P 0.00000003874 0.60018 36.755
305 4BCQ TJF 0.0000003295 0.64423 36.8771
306 4BCM T7Z 0.000002019 0.44047 36.8771
307 2XMY CDK 0.0000000216 0.66756 36.9128
308 4EUU BX7 0.0000000223 0.60966 36.9906
309 4JDI ANP 0.0000000001138 0.74553 36.9942
310 4BCN T9N 0.00000002189 0.69193 37
311 4CQE CQE 0.0000131 0.52007 37.0504
312 4M69 ANP 0.000000005671 0.59737 37.0607
313 3TKI S25 0.00000005328 0.63758 37.1517
314 2HY0 306 0.0000001939 0.64604 37.2671
315 4AG8 AXI 0.000004471 0.4625 37.3418
316 5LMK 6ZK 0.000001558 0.59411 37.3737
317 5U6C 7YS 0.000002185 0.55321 37.4603
318 3SLS ANP 0.0000000008087 0.6994 37.5
319 3SLS 77D 0.0109 0.40492 37.5
320 3IGO ANP 0.00000001376 0.64697 37.7143
321 2Y6O 1N1 0.00005435 0.49375 37.8007
322 4FL3 ANP 0.000000002095 0.68179 38
323 4K33 ACP 0.0000000005855 0.72426 38.1538
324 5JKG 6LF 0.00003091 0.50247 38.2637
325 2OFV 242 0.00006075 0.48745 38.2671
326 2PVF ACP 0.0000000008525 0.73748 38.3234
327 4BHN BH9 0.0000000008376 0.70785 38.3234
328 5CEO 50D 0.000001595 0.49116 38.3333
329 5MJA 7O3 0.000008053 0.56034 38.6885
330 5HQ0 LZ9 0.0000000008039 0.70862 38.7417
331 5TA6 79D 0.00002741 0.48046 38.8268
332 3GQI ACP 0.0000000008776 0.72643 38.9571
333 5VC5 96M 0.000009421 0.49818 39.1003
334 3DLS ADP 0.00000000161 0.56518 39.1045
335 1V0O INR 0.000000002408 0.69702 39.2361
336 1U59 STU 0.000000004704 0.69339 39.3728
337 3KN5 ANP 0.00000003501 0.52377 39.3846
338 4XLI 1N1 0.00001092 0.54731 39.5522
339 2YAB AMP 0.0000000000833 0.64849 39.7143
340 3EKK GS2 0.000002642 0.46832 39.7394
341 4BFM ANP 0.00000000005394 0.75961 39.8204
342 2WQN ADP 0.00000001206 0.70448 40
343 5EKO N17 0.0001275 0.47353 40
344 4G17 0VN 0.000007394 0.45007 40
345 5USZ SKE 0.0000002862 0.55702 40.1384
346 5VCV 1N1 0.0000004671 0.56913 40.1929
347 3BU5 ATP 0.00000006594 0.54094 40.1961
348 3SXF BK5 0.0000005487 0.49969 40.2857
349 3RI1 3RH 0.0000004693 0.55739 40.5751
350 4U0I 0LI 0.0001864 0.46152 40.6349
351 3SXS PP2 0.000001049 0.57323 40.6716
352 4CSV STI 0.000435 0.45126 40.7273
353 3C0G 3AM 0.00000002722 0.68734 40.8571
354 3HZT J60 0.0000001685 0.65869 40.8571
355 3G5D 1N1 0.00001387 0.4003 40.9091
356 3FHR P4O 0.00000005475 0.63683 41.0714
357 2X2M X2M 0.00000005521 0.62126 41.0828
358 5UR1 YY9 0.00003948 0.41211 41.1576
359 4N70 2HX 0.000000006669 0.4857 41.1585
360 4TWP AXI 0.000009206 0.41916 41.3284
361 2V7O DRN 0.00000000881 0.73421 41.6667
362 3BZ3 YAM 0.000002456 0.40517 41.6667
363 5FBN 5WF 0.000008816 0.46409 41.6974
364 3SRV S19 0.0000000006711 0.59452 41.8773
365 4I6H 1C8 0.00003296 0.51917 42.2078
366 3GC0 AMP 0.000007392 0.45548 42.2492
367 4F4P 0SB 0.000002819 0.56908 42.4908
368 2J7T 274 0.0001215 0.44232 42.7152
369 1BYG STU 0.000000003547 0.55955 42.8058
370 5DEY 59T 0.00009674 0.41461 43.0976
371 2WEL K88 0.0000007811 0.4305 43.1193
372 2X4Z X4Z 0.000006196 0.52642 43.2432
373 5IH9 6BF 0.0000006923 0.49217 43.2836
374 3CY2 MB9 0.000000003333 0.66499 43.3121
375 5DH3 5BS 0.000000269 0.5989 43.4921
376 3M2W L8I 0.0000000001621 0.79515 43.8127
377 5DRB 5FJ 0.000003887 0.43364 44.3299
378 2VZ6 FEF 0.000000003234 0.73217 44.4089
379 4KS7 X4Z 0.000001112 0.55957 44.5205
380 1ZY5 ANP 0.000001702 0.58469 44.8845
381 4OFG PCG 0.01208 0.41363 45.1389
382 4L9I 8PR 0.000000006513 0.6966 45.7143
383 5A6N U7E 0.000000018 0.56717 45.9364
384 2WEI VGG 0.000006968 0.56331 45.993
385 4A4X JUP 0.00001008 0.50478 46.2366
386 4WNP 3RJ 0.000000004692 0.72434 46.6899
387 4USF 6UI 0.0001135 0.45461 46.7105
388 2VN9 GVD 0.000000006015 0.74264 46.8439
389 5UOX 8GY 0.000000003951 0.67006 47.2325
390 4FG8 ATP 0.0000000001242 0.74388 47.619
391 2ZV2 609 0.000000001683 0.75795 47.651
392 1PHK ATP 0.00000000001066 0.67729 47.651
393 2YAK OSV 0.00000002623 0.57679 47.7193
394 5JZJ AN2 0.0000000000017 0.86249 48.4848
395 4WNK 453 0.0000000004021 0.64278 48.5714
396 2XK9 XK9 0.0000003463 0.57944 48.7578
397 5UKL SIX 0.00000002527 0.61011 50
398 3PVW QRX 0.00000006616 0.591 50
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