-->
Receptor
PDB id Resolution Class Description Source Keywords
2R7N 2.4 Å EC: 6.3.4.- CRYSTAL STRUCTURE OF FAICAR SYNTHETASE (PURP) FROM M. JANNAS COMPLEXED WITH ADP AND FAICAR METHANOCALDOCOCCUS JANNASCHII ATP-GRASP SUPERFAMILY ATP-BINDING LIGASE MAGNESIUM MANGAMETAL-BINDING NUCLEOTIDE-BINDING
Ref.: CRYSTAL STRUCTURE AND FUNCTION OF 5-FORMAMINOIMIDAZOLE-4-CARBOXAMIDE RIBONUCLEOTIDE S FROM METHANOCALDOCOCCUS JANNASCHII. BIOCHEMISTRY V. 47 205 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:400;
Valid;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
CL A:602;
Invalid;
none;
submit data
35.453 Cl [Cl-]
FAI A:401;
Valid;
none;
submit data
366.221 C10 H15 N4 O9 P c1nc(...
SO4 A:500;
Invalid;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2R7K 2.1 Å EC: 6.3.4.- CRYSTAL STRUCTURE OF FAICAR SYNTHETASE (PURP) FROM M. JANNAS COMPLEXED WITH AMPPCP AND AICAR METHANOCALDOCOCCUS JANNASCHII ATP-GRASP SUPERFAMILY ATP-BINDING LIGASE MAGNESIUM MANGAMETAL-BINDING NUCLEOTIDE-BINDING
Ref.: CRYSTAL STRUCTURE AND FUNCTION OF 5-FORMAMINOIMIDAZOLE-4-CARBOXAMIDE RIBONUCLEOTIDE S FROM METHANOCALDOCOCCUS JANNASCHII. BIOCHEMISTRY V. 47 205 2008
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2R7N - FAI C10 H15 N4 O9 P c1nc(c(n1[....
2 2R7L - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 2R7M - AMP C10 H14 N5 O7 P c1nc(c2c(n....
4 2R7K - AMZ C9 H15 N4 O8 P c1nc(c(n1[....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2R7N - FAI C10 H15 N4 O9 P c1nc(c(n1[....
2 2R7L - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
3 2R7M - AMP C10 H14 N5 O7 P c1nc(c2c(n....
4 2R7K - AMZ C9 H15 N4 O8 P c1nc(c(n1[....
50% Homology Family (8)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2R87 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
2 2R84 - AMZ C9 H15 N4 O8 P c1nc(c(n1[....
3 2R85 - AMP C10 H14 N5 O7 P c1nc(c2c(n....
4 2R86 - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
5 2R7N - FAI C10 H15 N4 O9 P c1nc(c(n1[....
6 2R7L - ATP C10 H16 N5 O13 P3 c1nc(c2c(n....
7 2R7M - AMP C10 H14 N5 O7 P c1nc(c2c(n....
8 2R7K - AMZ C9 H15 N4 O8 P c1nc(c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 452
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 HEJ 0.9 1
3 ATP 0.9 1
4 A2D 0.895522 0.971831
5 5FA 0.887324 1
6 AQP 0.887324 1
7 AP5 0.884058 0.971831
8 B4P 0.884058 0.971831
9 BA3 0.869565 0.971831
10 AN2 0.84507 0.985915
11 AT4 0.84507 0.958904
12 M33 0.833333 0.958333
13 ACQ 0.826667 0.972222
14 A 0.823529 0.971429
15 AMP 0.823529 0.971429
16 ACP 0.821918 0.972222
17 6YZ 0.818182 0.972222
18 APR 0.810811 0.971831
19 AR6 0.810811 0.971831
20 ANP 0.802632 0.972222
21 SAP 0.8 0.945946
22 AGS 0.8 0.945946
23 AD9 0.8 0.972222
24 ADX 0.783784 0.873418
25 CA0 0.783784 0.945205
26 TAT 0.779221 0.958904
27 T99 0.779221 0.958904
28 50T 0.773333 0.958333
29 ABM 0.763889 0.917808
30 APC 0.763158 0.958904
31 PRX 0.763158 0.893333
32 ATF 0.759494 0.958904
33 A22 0.753086 0.985915
34 AP2 0.743243 0.958904
35 A12 0.743243 0.958904
36 SRA 0.736111 0.918919
37 ADQ 0.73494 0.945205
38 25L 0.732558 0.985915
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 A3R 0.714286 0.907895
44 ATR 0.708861 0.971429
45 ADP PO3 0.708861 0.943662
46 PAP 0.708861 0.985714
47 SRP 0.707317 0.906667
48 7D3 0.706667 0.905405
49 25A 0.702381 0.971831
50 9X8 0.697674 0.92
51 OAD 0.697674 0.945205
52 RBY 0.6875 0.932432
53 ADV 0.6875 0.932432
54 00A 0.686047 0.883117
55 OOB 0.682353 0.931507
56 5SV 0.682353 0.848101
57 8QN 0.682353 0.931507
58 3OD 0.681818 0.945205
59 BIS 0.681818 0.933333
60 ALF ADP 0.674699 0.87013
61 ADP ALF 0.674699 0.87013
62 AMO 0.674419 0.932432
63 4AD 0.674419 0.92
64 PAJ 0.674419 0.884615
65 GAP 0.670732 0.893333
66 MAP 0.670588 0.945946
67 AHX 0.666667 0.896104
68 VO4 ADP 0.666667 0.931507
69 DLL 0.666667 0.931507
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LMS 0.653333 0.82716
75 LAD 0.651685 0.860759
76 WAQ 0.651685 0.883117
77 B5V 0.651685 0.906667
78 PR8 0.651685 0.85
79 ITT 0.65 0.943662
80 7D4 0.65 0.905405
81 G5P 0.648936 0.921053
82 XYA 0.647059 0.84507
83 ADN 0.647059 0.84507
84 RAB 0.647059 0.84507
85 1ZZ 0.644444 0.839506
86 ME8 0.644444 0.839506
87 FYA 0.644444 0.905405
88 NB8 0.644444 0.896104
89 TXA 0.644444 0.932432
90 6AD 0.642857 0.909091
91 ADP BMA 0.640449 0.918919
92 G3A 0.638298 0.921053
93 DAL AMP 0.632184 0.905405
94 AFH 0.631579 0.884615
95 9SN 0.630435 0.871795
96 9ZA 0.625 0.907895
97 DQV 0.625 0.958333
98 9ZD 0.625 0.907895
99 GTA 0.625 0.886076
100 YAP 0.623656 0.894737
101 B5M 0.623656 0.894737
102 FA5 0.623656 0.906667
103 B5Y 0.623656 0.894737
104 UP5 0.622449 0.92
105 HFD 0.619048 0.945946
106 XAH 0.617021 0.839506
107 AV2 0.616279 0.917808
108 AOC 0.615385 0.821918
109 48N 0.612245 0.896104
110 4UV 0.610526 0.894737
111 6V0 0.606061 0.896104
112 NAI 0.606061 0.907895
113 DND 0.606061 0.932432
114 NAX 0.606061 0.873418
115 NXX 0.606061 0.932432
116 TXD 0.606061 0.907895
117 5N5 0.605634 0.819444
118 5AS 0.604938 0.77907
119 A4P 0.60396 0.843373
120 DAT 0.60241 0.905405
121 A2R 0.602273 0.985915
122 TXE 0.6 0.907895
123 OMR 0.6 0.851852
124 4UU 0.597938 0.894737
125 GA7 0.597938 0.906667
126 A A 0.597826 0.944444
127 A4D 0.597222 0.819444
128 5CD 0.597222 0.805556
129 AP0 0.594059 0.896104
130 4TC 0.594059 0.896104
131 A3P 0.592593 0.971429
132 T5A 0.592233 0.841463
133 139 0.592233 0.873418
134 7D5 0.592105 0.878378
135 ATP A A A 0.589474 0.930556
136 LAQ 0.585859 0.839506
137 MYR AMP 0.585106 0.817073
138 F2R 0.580952 0.864198
139 YLP 0.58 0.819277
140 UPA 0.578431 0.907895
141 7DD 0.578313 0.985714
142 3AM 0.576923 0.929577
143 ADJ 0.576923 0.851852
144 COD 0.575472 0.811765
145 NAD 0.575472 0.931507
146 3AT 0.574713 0.971831
147 JB6 0.574468 0.883117
148 4UW 0.574257 0.860759
149 EP4 0.573333 0.753247
150 A2P 0.573171 0.957143
151 CNA 0.571429 0.932432
152 TYM 0.568627 0.906667
153 PPS 0.568182 0.873418
154 DTA 0.565789 0.786667
155 M2T 0.565789 0.734177
156 AR6 AR6 0.565657 0.917808
157 A3D 0.564815 0.918919
158 80F 0.564815 0.841463
159 3DH 0.564103 0.773333
160 G5A 0.563218 0.77907
161 YLB 0.563107 0.819277
162 YLC 0.563107 0.839506
163 AMP DBH 0.561224 0.893333
164 TYR AMP 0.561224 0.87013
165 MTA 0.558442 0.773333
166 DTP 0.556818 0.905405
167 AHZ 0.554455 0.817073
168 NA7 0.553191 0.958904
169 IOT 0.552381 0.831325
170 ZAS 0.55 0.766234
171 7MD 0.55 0.8625
172 ARG AMP 0.55 0.829268
173 IMO 0.548781 0.929577
174 YLA 0.54717 0.819277
175 NAE 0.544643 0.894737
176 TAD 0.544554 0.884615
177 A5A 0.544444 0.807229
178 2AM 0.544304 0.943662
179 TSB 0.543478 0.819277
180 6RE 0.54321 0.759494
181 AYB 0.542056 0.809524
182 NAQ 0.539823 0.871795
183 V3L 0.539326 0.971831
184 SSA 0.538462 0.8
185 AF3 ADP 3PG 0.538462 0.8375
186 ZID 0.535088 0.918919
187 LPA AMP 0.533981 0.817073
188 52H 0.532609 0.77907
189 VMS 0.532609 0.788235
190 54H 0.532609 0.788235
191 BTX 0.53211 0.841463
192 A3N 0.53012 0.786667
193 J7C 0.53012 0.769231
194 5X8 0.528736 0.763158
195 BT5 0.527273 0.831325
196 8X1 0.526882 0.752809
197 5CA 0.526882 0.8
198 53H 0.526882 0.77907
199 ARU 0.526316 0.860759
200 EAD 0.525862 0.873418
201 RGT 0.525253 0.958904
202 OVE 0.52439 0.905405
203 S4M 0.52381 0.666667
204 7DT 0.522727 0.985714
205 GDP 0.522222 0.92
206 DDS 0.522222 0.878378
207 AVV 0.521277 0.896104
208 NDE 0.521008 0.932432
209 7MC 0.518868 0.841463
210 DSH 0.518072 0.725
211 MAO 0.517647 0.759036
212 NSS 0.515789 0.8
213 DSZ 0.515789 0.8
214 LSS 0.515789 0.761364
215 P5A 0.515464 0.744444
216 DZD 0.513514 0.884615
217 NVA LMS 0.510417 0.752809
218 9K8 0.510204 0.714286
219 12D 0.509615 0.785714
220 M24 0.508772 0.85
221 YLY 0.508772 0.809524
222 P1H 0.508333 0.851852
223 5AD 0.506849 0.746479
224 GJV 0.505882 0.75
225 LEU LMS 0.505155 0.752809
226 AMP NAD 0.504505 0.905405
227 4TA 0.504505 0.807229
228 G A A A 0.504505 0.871795
229 NAJ PZO 0.504425 0.848101
230 GSU 0.5 0.77907
231 128 0.5 0.776471
232 KAA 0.5 0.752809
233 71V 0.5 0.907895
234 A3G 0.5 0.8
235 NDC 0.5 0.871795
236 7D7 0.5 0.743243
237 N0B 0.495726 0.819277
238 NJP 0.495495 0.945946
239 ODP 0.495495 0.909091
240 2SA 0.494624 0.932432
241 6C6 0.494505 0.881579
242 SFG 0.494382 0.75
243 0WD 0.491071 0.921053
244 YSA 0.490196 0.77907
245 PO4 PO4 A A A A PO4 0.489796 0.902778
246 SAM 0.48913 0.690476
247 6IA 0.48913 0.8375
248 A7D 0.488636 0.776316
249 6FA 0.488 0.841463
250 FB0 0.487805 0.804598
251 NAJ PYZ 0.487179 0.807229
252 A5D 0.483516 0.786667
253 IDP 0.483516 0.918919
254 SA8 0.483516 0.707317
255 PGS 0.483146 0.883117
256 MHZ 0.483146 0.697674
257 DA 0.482353 0.878378
258 D5M 0.482353 0.878378
259 NEC 0.482353 0.746667
260 NIA 0.481928 0.822785
261 Y3J 0.480519 0.726027
262 8PZ 0.480392 0.8
263 FAD 0.480315 0.851852
264 FAS 0.480315 0.851852
265 FDA 0.48 0.833333
266 N6P 0.479592 0.915493
267 GGZ 0.479167 0.825
268 U A 0.478261 0.907895
269 SAH 0.478261 0.74359
270 SAI 0.478261 0.734177
271 A G 0.477876 0.883117
272 NPW 0.477477 0.886076
273 NDP 0.477477 0.921053
274 AAM 0.476744 0.971429
275 C2R 0.47561 0.90411
276 AMZ 0.47561 0.916667
277 A A A 0.474747 0.905405
278 GTP 0.473684 0.92
279 U A G G 0.473684 0.883117
280 SMM 0.473684 0.686047
281 NZQ 0.473214 0.909091
282 TXP 0.473214 0.921053
283 A3S 0.47191 0.810811
284 SFD 0.46875 0.734043
285 AIR 0.468354 0.901408
286 AAT 0.468085 0.707317
287 EEM 0.468085 0.690476
288 J7V 0.466667 0.833333
289 Z5A 0.466667 0.77907
290 7C5 0.466667 0.818182
291 62F 0.465649 0.8625
292 HDV 0.463158 0.893333
293 FAY 0.462121 0.8625
294 A3T 0.461538 0.821918
295 ETB 0.461538 0.833333
296 DCA 0.461538 0.823529
297 A6D 0.46 0.722892
298 A U 0.459459 0.87013
299 GEK 0.459184 0.7375
300 6K6 0.459184 0.930556
301 RFL 0.458647 0.821429
302 NAP 0.458333 0.945205
303 S7M 0.458333 0.690476
304 4YB 0.457944 0.761364
305 WSA 0.454545 0.788235
306 TAP 0.454545 0.907895
307 FNK 0.454545 0.804598
308 COA 0.453782 0.823529
309 0T1 0.453782 0.823529
310 101 0.453488 0.878378
311 XNP 0.452174 0.873418
312 NA0 0.45082 0.932432
313 7RP 0.448276 0.928571
314 GP3 0.446809 0.921053
315 TM1 0.446602 0.77381
316 APU 0.446429 0.894737
317 PUA 0.445378 0.884615
318 V1N 0.443396 0.917808
319 7RA 0.443182 0.957747
320 COS 0.442623 0.804598
321 AMX 0.442623 0.833333
322 30N 0.442623 0.752688
323 CAO 0.442623 0.795455
324 QQY 0.44186 0.815789
325 ACK 0.44186 0.861111
326 649 0.441441 0.744444
327 0UM 0.44 0.698795
328 NHD 0.439655 0.905405
329 CMX 0.439024 0.823529
330 SCO 0.439024 0.823529
331 GCP 0.438776 0.896104
332 8BR 0.438202 0.906667
333 GNH 0.4375 0.907895
334 8Q2 0.4375 0.772727
335 3AD 0.4375 0.805556
336 NVA 2AD 0.43617 0.759494
337 62X 0.435644 0.666667
338 FCX 0.435484 0.795455
339 ACO 0.435484 0.795455
340 FAM 0.435484 0.804598
341 9JJ 0.434783 0.8625
342 GNP 0.434343 0.896104
343 9GM 0.434343 0.896104
344 NMX 0.433071 0.76087
345 MGP 0.43299 0.884615
346 26A 0.432099 0.763158
347 HAX 0.432 0.804598
348 K15 0.431373 0.682353
349 DG1 0.430894 0.921053
350 1DG 0.430894 0.921053
351 QQX 0.430233 0.805195
352 2VA 0.430108 0.8
353 S8M 0.43 0.759494
354 2MC 0.429688 0.769231
355 6G0 0.428571 0.884615
356 P5F 0.428571 0.823529
357 FYN 0.428571 0.823529
358 3KK 0.428571 0.804598
359 A C A C 0.428571 0.848101
360 7L1 0.427419 0.795455
361 FAI 0.426966 0.916667
362 RMB 0.426966 0.873239
363 AS 0.426966 0.833333
364 1RB 0.425287 0.885714
365 CA6 0.425197 0.729167
366 SOP 0.425197 0.804598
367 OXK 0.425197 0.804598
368 MCD 0.425197 0.804598
369 COK 0.425197 0.804598
370 G1R 0.424242 0.907895
371 SXZ 0.423077 0.710843
372 CC5 0.423077 0.816901
373 F2N 0.422535 0.813953
374 EO7 0.422222 0.788235
375 ANZ 0.422018 0.8
376 1VU 0.421875 0.795455
377 CMC 0.421875 0.804598
378 CO6 0.421875 0.804598
379 ZDA 0.421053 0.864865
380 GKE 0.420561 0.884615
381 GDC 0.420561 0.884615
382 GDD 0.420561 0.884615
383 NFD 0.420168 0.883117
384 GSP 0.42 0.873418
385 D3Y 0.42 0.789474
386 MC4 0.419847 0.76087
387 3D1 0.419753 0.773333
388 3L1 0.419753 0.773333
389 FA9 0.41958 0.864198
390 5GP 0.419355 0.906667
391 G 0.419355 0.906667
392 KB1 0.419048 0.698795
393 CAJ 0.418605 0.804598
394 SCD 0.418605 0.823529
395 CMP 0.417582 0.901408
396 2BA 0.417582 0.915493
397 SO8 0.416667 0.789474
398 VRT 0.416667 0.769231
399 N01 0.416667 0.905405
400 IVC 0.415385 0.813953
401 1HE 0.415385 0.786517
402 A1S 0.415385 0.804598
403 BCO 0.415385 0.804598
404 3HC 0.415385 0.813953
405 MLC 0.415385 0.804598
406 NMN AMP PO4 0.415254 0.87013
407 2FA 0.414634 0.813333
408 MGO 0.414141 0.860759
409 3NZ 0.413462 0.782051
410 COO 0.412214 0.804598
411 MCA 0.412214 0.795455
412 YE1 0.412214 0.813953
413 CAA 0.412214 0.813953
414 GAV 0.411765 0.884615
415 PRT 0.411215 0.931507
416 JLN 0.411111 0.890411
417 P2P 0.411111 0.902778
418 ZZB 0.410256 0.77381
419 SP1 0.409091 0.842105
420 RP1 0.409091 0.842105
421 2CP 0.409091 0.795455
422 SCA 0.409091 0.804598
423 103 0.409091 0.837838
424 PAX 0.408 0.829268
425 FAD NBT 0.407143 0.75
426 COW 0.406015 0.795455
427 3CP 0.406015 0.804598
428 IRC 0.406015 0.813953
429 BYC 0.406015 0.804598
430 CA8 0.406015 0.729167
431 1GZ 0.406015 0.795455
432 COF 0.406015 0.786517
433 HGG 0.406015 0.804598
434 2KQ 0.406015 0.786517
435 G2P 0.405941 0.884615
436 SLU 0.404959 0.770115
437 U A C C 0.404959 0.858974
438 RBZ 0.404494 0.849315
439 1CZ 0.404412 0.795455
440 FAQ 0.402985 0.804598
441 BCA 0.402985 0.795455
442 4CA 0.402985 0.795455
443 MTP 0.402439 0.730769
444 8OD 0.402062 0.945205
445 CO7 0.401515 0.804598
446 GRA 0.4 0.804598
447 G2R 0.4 0.884615
448 ENQ 0.4 0.916667
449 CNV FAD 0.4 0.8
450 GMV 0.4 0.896104
451 HXC 0.4 0.786517
452 HF7 0.4 0.893333
Ligand no: 2; Ligand: FAI; Similar ligands found: 66
No: Ligand ECFP6 Tc MDL keys Tc
1 FAI 1 1
2 JLN 0.797101 0.971014
3 2ER 0.647727 0.931507
4 AMZ 0.638889 1
5 C2R 0.594595 0.985507
6 1PR 0.593407 0.918919
7 GUO 0.550562 0.971429
8 NIA 0.538462 0.868421
9 AIR 0.506667 0.955882
10 AAM 0.493976 0.888889
11 AMP 0.493827 0.888889
12 A 0.493827 0.888889
13 RBZ 0.487805 0.821918
14 RVP 0.487179 0.9
15 71V 0.482353 0.833333
16 7RP 0.481928 0.847222
17 7RA 0.47619 0.876712
18 1RB 0.47561 0.830986
19 5GP 0.465909 0.905405
20 G 0.465909 0.905405
21 P2P 0.458824 0.824324
22 IMO 0.458824 0.849315
23 RMB 0.458824 0.819444
24 CA0 0.449438 0.891892
25 PMO 0.448276 0.797297
26 2SA 0.446809 0.88
27 IMP 0.443182 0.90411
28 93A 0.438202 0.82716
29 PGS 0.433333 0.810127
30 6C6 0.430108 0.807692
31 ADP 0.426966 0.916667
32 6IA 0.425532 0.768293
33 A2D 0.425287 0.890411
34 5AL 0.421053 0.878378
35 BA3 0.41573 0.890411
36 IRN 0.415584 0.867647
37 MZP 0.414634 0.9
38 25A 0.414141 0.890411
39 ATP 0.413043 0.916667
40 HEJ 0.413043 0.916667
41 50T 0.413043 0.878378
42 SRP 0.412371 0.855263
43 B4P 0.411111 0.890411
44 AP5 0.411111 0.890411
45 ACQ 0.410526 0.891892
46 ABM 0.409091 0.84
47 5FA 0.408602 0.916667
48 AQP 0.408602 0.916667
49 APC 0.408602 0.88
50 MZR 0.407895 0.8
51 PTJ 0.407767 0.846154
52 AN2 0.406593 0.90411
53 AT4 0.406593 0.88
54 G7M 0.406593 0.87013
55 DLL 0.405941 0.878378
56 SAP 0.404255 0.868421
57 AGS 0.404255 0.868421
58 AU1 0.402174 0.891892
59 ITT 0.402174 0.863014
60 ADX 0.402174 0.802469
61 M33 0.402174 0.878378
62 8QN 0.4 0.878378
63 AP2 0.4 0.88
64 A12 0.4 0.88
65 OOB 0.4 0.878378
66 6K6 0.4 0.851351
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2R7K; Ligand: ACP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2R7K; Ligand: ACP; Similar sites found with APoc: 273
This union binding pocket(no: 2) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 5KK4 44E None
2 3HAV ATP 1.33779
3 2E40 LGC 1.38504
4 1IA9 ANP 1.42857
5 6FYV 3NG 1.48368
6 5YK1 ANP 1.66205
7 1Q8Y ADE 1.66205
8 3K5I ADP 1.66205
9 6GZD LCI 1.66205
10 5ZTN CUR 1.66205
11 4Y0X ADP 1.66205
12 3K5I AIR 1.66205
13 3GC0 AMP 1.82371
14 3AKK ADP 1.84615
15 3LXN MI1 1.88679
16 2PZI AXX 1.93906
17 2PUL ACP 1.93906
18 4UWH JXM 1.93906
19 3UDZ ADP 1.93906
20 5ZCT ANP 1.96078
21 1OBD ATP 1.96078
22 1ZY5 ANP 1.9802
23 3GGF GVD 1.99336
24 5YF9 NIO 2.0649
25 4CS9 AMP 2.1164
26 1BYG STU 2.15827
27 1GSA ADP 2.21519
28 4XH0 ADP 2.21607
29 5I35 ANP 2.21607
30 1I7E IBS 2.26415
31 4GLW 0XT 2.29508
32 2Q7D ANP 2.31214
33 6F3G CJN 2.37288
34 2PVF ACP 2.39521
35 1TQP ATP 2.48227
36 2Z7R STU 2.49221
37 3X01 AMP 2.49307
38 2YAB AMP 2.49307
39 2H8H H8H 2.49307
40 4OAV ACP 2.49307
41 4H3P ANP 2.49307
42 4CYI ATP 2.49307
43 5HVJ ANP 2.53968
44 2X2M X2M 2.54777
45 2WQN ADP 2.58065
46 1E4E ADP 2.62391
47 5WNL STU 2.63158
48 4Y8D 49J 2.64706
49 4I94 ANP 2.66667
50 5UPK ANP 2.7027
51 4OH4 ANP 2.7027
52 5LPZ ADP 2.71084
53 4NZN ANP 2.72727
54 4NZN 2OU 2.72727
55 5CKW ANP 2.77008
56 3TII ANP 2.77008
57 1U59 STU 2.78746
58 6CMJ F6J 2.80374
59 5ODT ADP 2.82686
60 5LXM ADP 2.82686
61 5Y80 IRE 2.8754
62 3I0O ADP 2.94985
63 2V7O DRN 2.97619
64 3E5A VX6 2.98507
65 1CKN GTP 3.0303
66 1CKM GTP 3.0303
67 5LPB ADP 3.04054
68 2R5T ANP 3.04709
69 3UIM ANP 3.06748
70 4IDT T28 3.08989
71 4DFU QUE 3.10559
72 3IDB ANP 3.10559
73 1P6O HPY 3.10559
74 2B9J ADP 3.11615
75 2B9F ADP 3.11615
76 2B9I ADP 3.11615
77 3W0O HY0 3.15186
78 3W0O ADP 3.15186
79 2F57 23D 3.15457
80 4FG8 ATP 3.1746
81 2QLU ADE 3.18471
82 2VZ6 FEF 3.19489
83 4O4F ATP 3.22581
84 4O4F IHP 3.22581
85 5AX9 4KT 3.24675
86 4OUJ LBT 3.25733
87 4Y85 499 3.31325
88 4DC2 ADE 3.3241
89 3UG4 AHR 3.3241
90 4GYI ADP 3.3241
91 4G17 0VN 3.33333
92 2REG CHT 3.3557
93 3ALN ANP 3.36391
94 4AU8 Z3R 3.37838
95 5LI1 ANP 3.38983
96 4KS7 X4Z 3.42466
97 5LI9 ACP 3.42857
98 2XOC ADP 3.44828
99 2AQX ATP 3.46021
100 4XZ3 ACP 3.47826
101 5C1P ADP 3.59477
102 5C1P DAL DAL 3.59477
103 1PK8 ATP 3.60111
104 5M06 ADP 3.62319
105 4MV1 ADP 3.63248
106 3TXO 07U 3.68272
107 2ZV2 609 3.69128
108 5TDF ADP 3.7037
109 3CQL NDG 3.7037
110 4LH7 1X8 3.71517
111 5T8O 76Z 3.72493
112 2QX0 PH2 3.77358
113 2GQR ADP 3.79747
114 3FHR P4O 3.86905
115 2IF8 ADP 3.87812
116 3HZT J60 3.87812
117 2VQD AP2 3.87812
118 4BHN BH9 3.89222
119 4XYM A12 3.91304
120 4IX4 ADP 4
121 3M2W L8I 4.01338
122 5JZJ AN2 4.0404
123 4PZ6 GMP 4.15512
124 5Y86 HRM 4.15512
125 1KJ8 ATP 4.15512
126 1KJ8 GAR 4.15512
127 1EHI ADP 4.15512
128 3VOT ADP 4.15512
129 1AUX AGS 4.18006
130 1I7L ATP 4.20712
131 4R78 AMP 4.20712
132 3ETH ATP 4.22535
133 1IOW PHY 4.24837
134 1IOW ADP 4.24837
135 5K2M ADP 4.3956
136 5VLQ ANP 4.43213
137 5MW8 ATP 4.43213
138 3TPV ADE 4.43213
139 6BGC BGC 4.43213
140 3DNT ATP 4.43213
141 3CY2 MB9 4.4586
142 4X7Q 3YR 4.48718
143 4I6H 1C8 4.54545
144 4NST ADP 4.5584
145 5KO1 6UY 4.59364
146 4CFU 2WC 4.62046
147 6GUE FB8 4.63576
148 4BCM T7Z 4.65116
149 4BCQ TJF 4.65116
150 4UXL 5P8 4.65839
151 4BCN T9N 4.66667
152 1K3A ACP 4.68227
153 2QK4 ATP 4.70914
154 4PU5 ANP 4.70914
155 5U6C 7YS 4.7619
156 2QCS ANP 4.811
157 4WW7 AMP 4.81283
158 4F9C 0SX 4.86111
159 4WNP 3RJ 4.87805
160 1T36 ADP 4.98615
161 5Z49 RUB 5.02092
162 4AUA 4AU 5.21173
163 3KN5 ANP 5.23077
164 2F2U M77 5.26316
165 3V8S 0HD 5.26316
166 5AWM ANP 5.32995
167 4BTK DTQ 5.34125
168 3RE4 TO1 5.42636
169 1ZTH ADP 5.42636
170 1ZP9 ATP 5.42636
171 3AQV TAK 5.43478
172 3WO0 ALA 5.54017
173 3WO0 ADP 5.54017
174 2BMB PMM 5.54017
175 4YMJ 4EJ 5.59211
176 3FW3 GLC 5.6391
177 4U44 3D9 5.72289
178 3WVR AMP 5.81717
179 4AZW ATP 5.81717
180 4NFN 2KC 5.82524
181 4YZN 4K5 5.92335
182 5L8L ADP 5.98291
183 3PLS ANP 6.04027
184 4C2W ANP 6.09319
185 1CM8 ANP 6.09418
186 6BFN DL1 6.14035
187 4JR7 GNP 6.14973
188 4OTH DRN 6.15836
189 4NFE BEN 6.32911
190 5X8I SQZ 6.37119
191 2CFM AMP 6.37119
192 1S68 AMP 6.4257
193 5EFQ ADP 6.62824
194 1M0W ANP 6.6482
195 3V4S ADP 6.6482
196 3V4S ATP 6.6482
197 3ORQ ADP 6.6482
198 4O1P ANP 6.6482
199 2VPQ ANP 6.65188
200 2WEL K88 6.66667
201 3O0G 3O0 6.71141
202 5A6N U7E 6.71378
203 1UNH IXM 6.73077
204 3VPD ANP 6.76157
205 6G33 5ID 6.78466
206 1U5R ATP 6.89655
207 1TZD ADP 6.90909
208 2YRX AMP 6.92521
209 2VN9 GVD 6.97674
210 5C03 AGS 7.01754
211 4LRJ ANP 7.10059
212 5EQY 5RA 7.20222
213 5DMZ ADP 7.20222
214 4USF 6UI 7.23684
215 1XJD STU 7.24638
216 6MJ7 ARG 7.27273
217 2A19 ANP 7.42857
218 4BFM ANP 7.48503
219 1W2D ADP 7.54717
220 1W2D 4IP 7.54717
221 4KBA 1QM 7.55287
222 4WOV 3SM 7.57098
223 1V0O INR 7.63889
224 6E8I PTR 7.69231
225 5DZT AMP 7.75623
226 6AC9 ANP 7.75623
227 3ZRM ZRM 7.75623
228 2PYW ADP 7.75623
229 2JLD AG1 7.75623
230 2HY0 306 7.76398
231 1IR3 ANP 7.84314
232 5COU ATP 7.94118
233 3SRV S19 7.94224
234 5OKT 9XK 7.96178
235 1O9U ADZ 8
236 3F7Z 34O 8
237 4ZS4 ATP 8.14332
238 5LXT ACP 8.31025
239 2YW2 ATP 8.31025
240 4WTV ATP 8.58726
241 4U98 ACP 8.58726
242 5VZ0 ADP 8.86427
243 4UX9 ANP 8.86427
244 4CFT M48 8.86427
245 3PDT ADP 9.09091
246 2HGS ADP 9.41828
247 4OCV ANP 9.69529
248 4CC6 L5Y 9.74843
249 6GU6 1QK 9.93377
250 3KMW ATP 9.9631
251 4NM5 ADP 10.3448
252 6CQF F97 10.4377
253 5HQ0 LZ9 10.6227
254 3H9R TAK 11.0092
255 5OES ADP 11.0803
256 4UAL 3FV 11.0803
257 1Z2P I3S 11.1111
258 1Z2P ACP 11.1111
259 4Q5H ANP 11.4943
260 3PN1 IVH 11.6352
261 1JPA ANP 12.8205
262 3DLS ADP 13.4328
263 3KAL ADP 13.5734
264 2GQS ADP 14.346
265 3VPB ADP 14.539
266 3VPC ADP 14.539
267 2V58 LZJ 15.1448
268 3C0G 3AM 17.094
269 5G1X ADP 17.4603
270 3DAK ANP 18.6207
271 2BKK ADP 23.6686
272 5LVP ATP 33.3333
273 3BU5 ATP 33.3333
Pocket No.: 3; Query (leader) PDB : 2R7K; Ligand: ACP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2R7K; Ligand: ACP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 5; Query (leader) PDB : 2R7K; Ligand: ACP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 5) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 6; Query (leader) PDB : 2R7K; Ligand: ACP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 6) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 7; Query (leader) PDB : 2R7K; Ligand: AMZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 7) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 8; Query (leader) PDB : 2R7K; Ligand: AMZ; Similar sites found with APoc: 273
This union binding pocket(no: 8) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
1 5KK4 44E None
2 3HAV ATP 1.33779
3 2E40 LGC 1.38504
4 1IA9 ANP 1.42857
5 6FYV 3NG 1.48368
6 5YK1 ANP 1.66205
7 1Q8Y ADE 1.66205
8 3K5I ADP 1.66205
9 6GZD LCI 1.66205
10 5ZTN CUR 1.66205
11 4Y0X ADP 1.66205
12 3K5I AIR 1.66205
13 3GC0 AMP 1.82371
14 3AKK ADP 1.84615
15 3LXN MI1 1.88679
16 2PZI AXX 1.93906
17 2PUL ACP 1.93906
18 4UWH JXM 1.93906
19 3UDZ ADP 1.93906
20 5ZCT ANP 1.96078
21 1OBD ATP 1.96078
22 1ZY5 ANP 1.9802
23 3GGF GVD 1.99336
24 5YF9 NIO 2.0649
25 4CS9 AMP 2.1164
26 1BYG STU 2.15827
27 1GSA ADP 2.21519
28 4XH0 ADP 2.21607
29 5I35 ANP 2.21607
30 1I7E IBS 2.26415
31 4GLW 0XT 2.29508
32 2Q7D ANP 2.31214
33 6F3G CJN 2.37288
34 2PVF ACP 2.39521
35 1TQP ATP 2.48227
36 2Z7R STU 2.49221
37 3X01 AMP 2.49307
38 2YAB AMP 2.49307
39 2H8H H8H 2.49307
40 4OAV ACP 2.49307
41 4H3P ANP 2.49307
42 4CYI ATP 2.49307
43 5HVJ ANP 2.53968
44 2X2M X2M 2.54777
45 2WQN ADP 2.58065
46 1E4E ADP 2.62391
47 5WNL STU 2.63158
48 4Y8D 49J 2.64706
49 4I94 ANP 2.66667
50 5UPK ANP 2.7027
51 4OH4 ANP 2.7027
52 5LPZ ADP 2.71084
53 4NZN ANP 2.72727
54 4NZN 2OU 2.72727
55 5CKW ANP 2.77008
56 3TII ANP 2.77008
57 1U59 STU 2.78746
58 6CMJ F6J 2.80374
59 5ODT ADP 2.82686
60 5LXM ADP 2.82686
61 5Y80 IRE 2.8754
62 3I0O ADP 2.94985
63 2V7O DRN 2.97619
64 3E5A VX6 2.98507
65 1CKN GTP 3.0303
66 1CKM GTP 3.0303
67 5LPB ADP 3.04054
68 2R5T ANP 3.04709
69 3UIM ANP 3.06748
70 4IDT T28 3.08989
71 4DFU QUE 3.10559
72 3IDB ANP 3.10559
73 1P6O HPY 3.10559
74 2B9J ADP 3.11615
75 2B9F ADP 3.11615
76 2B9I ADP 3.11615
77 3W0O HY0 3.15186
78 3W0O ADP 3.15186
79 2F57 23D 3.15457
80 4FG8 ATP 3.1746
81 2QLU ADE 3.18471
82 2VZ6 FEF 3.19489
83 4O4F ATP 3.22581
84 4O4F IHP 3.22581
85 5AX9 4KT 3.24675
86 4OUJ LBT 3.25733
87 4Y85 499 3.31325
88 4DC2 ADE 3.3241
89 3UG4 AHR 3.3241
90 4GYI ADP 3.3241
91 4G17 0VN 3.33333
92 2REG CHT 3.3557
93 3ALN ANP 3.36391
94 4AU8 Z3R 3.37838
95 5LI1 ANP 3.38983
96 4KS7 X4Z 3.42466
97 5LI9 ACP 3.42857
98 2XOC ADP 3.44828
99 2AQX ATP 3.46021
100 4XZ3 ACP 3.47826
101 5C1P ADP 3.59477
102 5C1P DAL DAL 3.59477
103 1PK8 ATP 3.60111
104 5M06 ADP 3.62319
105 4MV1 ADP 3.63248
106 3TXO 07U 3.68272
107 2ZV2 609 3.69128
108 5TDF ADP 3.7037
109 3CQL NDG 3.7037
110 4LH7 1X8 3.71517
111 5T8O 76Z 3.72493
112 2QX0 PH2 3.77358
113 2GQR ADP 3.79747
114 3FHR P4O 3.86905
115 2IF8 ADP 3.87812
116 3HZT J60 3.87812
117 2VQD AP2 3.87812
118 4BHN BH9 3.89222
119 4XYM A12 3.91304
120 4IX4 ADP 4
121 3M2W L8I 4.01338
122 5JZJ AN2 4.0404
123 4PZ6 GMP 4.15512
124 5Y86 HRM 4.15512
125 1KJ8 ATP 4.15512
126 1KJ8 GAR 4.15512
127 1EHI ADP 4.15512
128 3VOT ADP 4.15512
129 1AUX AGS 4.18006
130 1I7L ATP 4.20712
131 4R78 AMP 4.20712
132 3ETH ATP 4.22535
133 1IOW PHY 4.24837
134 1IOW ADP 4.24837
135 5K2M ADP 4.3956
136 5VLQ ANP 4.43213
137 5MW8 ATP 4.43213
138 3TPV ADE 4.43213
139 6BGC BGC 4.43213
140 3DNT ATP 4.43213
141 3CY2 MB9 4.4586
142 4X7Q 3YR 4.48718
143 4I6H 1C8 4.54545
144 4NST ADP 4.5584
145 5KO1 6UY 4.59364
146 4CFU 2WC 4.62046
147 6GUE FB8 4.63576
148 4BCM T7Z 4.65116
149 4BCQ TJF 4.65116
150 4UXL 5P8 4.65839
151 4BCN T9N 4.66667
152 1K3A ACP 4.68227
153 2QK4 ATP 4.70914
154 4PU5 ANP 4.70914
155 5U6C 7YS 4.7619
156 2QCS ANP 4.811
157 4WW7 AMP 4.81283
158 4F9C 0SX 4.86111
159 4WNP 3RJ 4.87805
160 1T36 ADP 4.98615
161 5Z49 RUB 5.02092
162 4AUA 4AU 5.21173
163 3KN5 ANP 5.23077
164 2F2U M77 5.26316
165 3V8S 0HD 5.26316
166 5AWM ANP 5.32995
167 4BTK DTQ 5.34125
168 3RE4 TO1 5.42636
169 1ZTH ADP 5.42636
170 1ZP9 ATP 5.42636
171 3AQV TAK 5.43478
172 3WO0 ALA 5.54017
173 3WO0 ADP 5.54017
174 2BMB PMM 5.54017
175 4YMJ 4EJ 5.59211
176 3FW3 GLC 5.6391
177 4U44 3D9 5.72289
178 3WVR AMP 5.81717
179 4AZW ATP 5.81717
180 4NFN 2KC 5.82524
181 4YZN 4K5 5.92335
182 5L8L ADP 5.98291
183 3PLS ANP 6.04027
184 4C2W ANP 6.09319
185 1CM8 ANP 6.09418
186 6BFN DL1 6.14035
187 4JR7 GNP 6.14973
188 4OTH DRN 6.15836
189 4NFE BEN 6.32911
190 5X8I SQZ 6.37119
191 2CFM AMP 6.37119
192 1S68 AMP 6.4257
193 5EFQ ADP 6.62824
194 1M0W ANP 6.6482
195 3V4S ADP 6.6482
196 3V4S ATP 6.6482
197 3ORQ ADP 6.6482
198 4O1P ANP 6.6482
199 2VPQ ANP 6.65188
200 2WEL K88 6.66667
201 3O0G 3O0 6.71141
202 5A6N U7E 6.71378
203 1UNH IXM 6.73077
204 3VPD ANP 6.76157
205 6G33 5ID 6.78466
206 1U5R ATP 6.89655
207 1TZD ADP 6.90909
208 2YRX AMP 6.92521
209 2VN9 GVD 6.97674
210 5C03 AGS 7.01754
211 4LRJ ANP 7.10059
212 5EQY 5RA 7.20222
213 5DMZ ADP 7.20222
214 4USF 6UI 7.23684
215 1XJD STU 7.24638
216 6MJ7 ARG 7.27273
217 2A19 ANP 7.42857
218 4BFM ANP 7.48503
219 1W2D ADP 7.54717
220 1W2D 4IP 7.54717
221 4KBA 1QM 7.55287
222 4WOV 3SM 7.57098
223 1V0O INR 7.63889
224 6E8I PTR 7.69231
225 5DZT AMP 7.75623
226 6AC9 ANP 7.75623
227 3ZRM ZRM 7.75623
228 2PYW ADP 7.75623
229 2JLD AG1 7.75623
230 2HY0 306 7.76398
231 1IR3 ANP 7.84314
232 5COU ATP 7.94118
233 3SRV S19 7.94224
234 5OKT 9XK 7.96178
235 1O9U ADZ 8
236 3F7Z 34O 8
237 4ZS4 ATP 8.14332
238 5LXT ACP 8.31025
239 2YW2 ATP 8.31025
240 4WTV ATP 8.58726
241 4U98 ACP 8.58726
242 5VZ0 ADP 8.86427
243 4UX9 ANP 8.86427
244 4CFT M48 8.86427
245 3PDT ADP 9.09091
246 2HGS ADP 9.41828
247 4OCV ANP 9.69529
248 4CC6 L5Y 9.74843
249 6GU6 1QK 9.93377
250 3KMW ATP 9.9631
251 4NM5 ADP 10.3448
252 6CQF F97 10.4377
253 5HQ0 LZ9 10.6227
254 3H9R TAK 11.0092
255 5OES ADP 11.0803
256 4UAL 3FV 11.0803
257 1Z2P I3S 11.1111
258 1Z2P ACP 11.1111
259 4Q5H ANP 11.4943
260 3PN1 IVH 11.6352
261 1JPA ANP 12.8205
262 3DLS ADP 13.4328
263 3KAL ADP 13.5734
264 2GQS ADP 14.346
265 3VPB ADP 14.539
266 3VPC ADP 14.539
267 2V58 LZJ 15.1448
268 3C0G 3AM 17.094
269 5G1X ADP 17.4603
270 3DAK ANP 18.6207
271 2BKK ADP 23.6686
272 5LVP ATP 33.3333
273 3BU5 ATP 33.3333
Pocket No.: 9; Query (leader) PDB : 2R7K; Ligand: AMZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 9) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 10; Query (leader) PDB : 2R7K; Ligand: AMZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 2R7K; Ligand: AMZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 2R7K; Ligand: AMZ; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 2r7k.bio1) has 29 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback