Receptor
PDB id Resolution Class Description Source Keywords
2RFX 2.5 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF HLA-B*5701, PRESENTING THE SELF PEPTIDE LSSPVTKSF HOMO SAPIENS ALPHA BETA SANDWICH-IMMUNOLOGLOBULIN LIKE GLYCOPROTEIN HOSINTERACTION IMMUNE RESPONSE MEMBRANE MHC I TRANSMEMBRANDISEASE MUTATION GLYCATION IMMUNOGLOBULIN DOMAIN PYRROLICARBOXYLIC ACID SECRETED IMMUNE SYSTEM
Ref.: HUMAN LEUKOCYTE ANTIGEN CLASS I-RESTRICTED ACTIVATI CD8+ T CELLS PROVIDES THE IMMUNOGENETIC BASIS OF A DRUG HYPERSENSITIVITY IMMUNITY V. 28 822 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:3731;
A:3732;
B:3731;
B:3732;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
LEU SER SER PRO VAL THR LYS SER PHE C:1;
Valid;
none;
submit data
951.133 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2RFX 2.5 Å NON-ENZYME: IMMUNE CRYSTAL STRUCTURE OF HLA-B*5701, PRESENTING THE SELF PEPTIDE LSSPVTKSF HOMO SAPIENS ALPHA BETA SANDWICH-IMMUNOLOGLOBULIN LIKE GLYCOPROTEIN HOSINTERACTION IMMUNE RESPONSE MEMBRANE MHC I TRANSMEMBRANDISEASE MUTATION GLYCATION IMMUNOGLOBULIN DOMAIN PYRROLICARBOXYLIC ACID SECRETED IMMUNE SYSTEM
Ref.: HUMAN LEUKOCYTE ANTIGEN CLASS I-RESTRICTED ACTIVATI CD8+ T CELLS PROVIDES THE IMMUNOGENETIC BASIS OF A DRUG HYPERSENSITIVITY IMMUNITY V. 28 822 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 222 families.
1 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
70% Homology Family (393)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 67 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 6PYL - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
11 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
12 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
13 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
14 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
15 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
16 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
17 6PYJ - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
18 6MTL - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
19 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
20 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
21 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
22 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
23 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
24 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
25 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
26 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
27 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
28 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
29 6PYW - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
30 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
31 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
32 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
33 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
34 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
35 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
36 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
37 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
38 6MT3 - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
39 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
40 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
41 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
42 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
43 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
44 6MT4 - PHE GLU ASP LEU ARG VAL SER SER PHE n/a n/a
45 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
46 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
47 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
48 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
49 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
50 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
51 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
52 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
53 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
54 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
55 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
56 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
57 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
58 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
59 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
60 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
61 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
62 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
63 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
64 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
65 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
66 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
67 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
68 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
69 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
70 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
72 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
73 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
74 6PZ5 - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
75 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
76 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
77 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
78 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
79 6PYV - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
80 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
81 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
82 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
83 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
84 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
85 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
86 6MT5 - PHE GLU ASP LEU ARG LEU LEU SER PHE n/a n/a
87 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
88 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
89 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
90 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
91 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
92 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
93 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
94 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
95 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
96 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
97 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
98 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
99 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
100 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
101 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
102 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
103 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
104 6MT6 - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
105 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
106 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
107 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
108 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
109 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
110 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
111 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
112 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
113 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
114 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
115 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
116 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
117 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
118 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
119 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
120 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
121 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
122 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
123 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
124 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
125 6PTE - ILE LEU ASN ALA MET ILE THR LYS ILE n/a n/a
126 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
127 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
128 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
129 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
130 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
131 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
132 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
133 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
134 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
135 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
136 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
137 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
138 6J1V - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
139 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
140 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
141 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
142 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
143 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
144 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
145 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
146 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
147 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
148 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
149 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
150 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
151 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
152 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
153 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
154 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
155 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
156 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
157 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
158 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
159 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
160 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
161 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
162 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
163 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
164 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
165 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
166 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
167 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
168 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
169 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
170 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
171 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
172 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
173 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
174 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
175 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
176 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
177 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
178 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
179 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
180 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
181 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
182 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
183 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
184 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
185 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
186 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
187 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
188 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
189 6PTB - ILE LEU ASN ALA MET ILE ALA LYS ILE n/a n/a
190 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
191 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
192 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
193 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
194 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
195 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
196 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
197 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
198 6G3J - MET THR SER ALA ILE GLY ILE LEU PRO VAL n/a n/a
199 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
200 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
201 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
202 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
203 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
204 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
205 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
206 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
207 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
208 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
209 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
210 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
211 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
212 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
213 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
214 6J2A - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
215 6J29 - GLN ILE MET TYR ASN TYR PRO ALA MET n/a n/a
216 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
217 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
218 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
219 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
220 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
221 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
222 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
223 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
224 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
225 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
226 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
227 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
228 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
229 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
230 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
231 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
232 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
233 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
234 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
235 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
236 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
237 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
238 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
239 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
240 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
241 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
242 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
243 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
244 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
245 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
246 6OPD - ILE LEU ASN ALA MET ILE VAL LYS ILE n/a n/a
247 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
248 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
249 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
251 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
252 6J1W - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
253 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
254 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
255 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
256 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
257 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
258 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
259 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
260 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
261 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
262 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
263 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
264 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
265 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
266 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
267 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
268 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
269 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
270 1HSB - ALA VAL ALA n/a n/a
271 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
272 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
273 5GRG - SER SER CYS SER SER CYS n/a n/a
274 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
275 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
276 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
277 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
278 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
279 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
281 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
282 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
283 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
284 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
285 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
286 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
288 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
289 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
291 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
292 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
293 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
294 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
295 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
296 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
297 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
298 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
299 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
300 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
301 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
302 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
303 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
304 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
305 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
306 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
307 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
308 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
309 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
310 6GB6 - GLY LEU n/a n/a
311 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
312 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
313 6IWG - MYR GLY GLY ALA ILE n/a n/a
314 6IWH - MYR GLY GLY GLY ILE n/a n/a
315 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
316 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
317 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
318 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
319 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
320 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
321 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
322 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
323 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
324 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
325 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
326 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
327 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
328 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
329 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
330 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
331 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
332 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
333 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
334 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
335 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
336 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
337 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
338 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
339 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
340 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
341 6J2E - ASP PHE GLN GLU SER ALA ASP SER PHE LEU n/a n/a
342 6J2J - ASP PHE THR CYS SER GLN ILE SER PRO n/a n/a
343 6J2H - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
344 6K7T - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
345 6J2I - ASP PHE GLU LYS GLU GLY TYR SER LEU n/a n/a
346 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
347 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
348 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
349 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
350 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
351 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
352 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
353 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
354 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
355 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
356 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
357 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
358 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
359 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
360 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
361 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
362 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
363 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
364 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
365 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
366 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
367 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
368 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
369 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
370 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
371 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
372 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
373 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
374 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
375 6O9B - THR THR ALA PRO SER LEU SER GLY LYS n/a n/a
376 6O9C - THR THR ALA PRO PHE LEU SER GLY LYS n/a n/a
377 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
378 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
379 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
380 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
381 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
382 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
383 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
384 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
385 6J2F - ASP TYR ILE ASN THR ASN VAL LEU PRO n/a n/a
386 6J2D - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
387 6ILC - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
388 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
389 6GB5 - PHE ALA PRO GLY ASN TYR PRO n/a n/a
390 6GB7 - GLU ASP ALA GLY GLY GLY GLY LEU SER LYS n/a n/a
391 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
392 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
393 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
50% Homology Family (399)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 45 families.
1 4QRT - GLU LEU ASN ARG LYS MET ILE TYR MET n/a n/a
2 3KPN - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
3 4U1H - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
4 3LKP - LEU PRO PHE ASP LYS SER THR ILE MET n/a n/a
5 1A9E - LEU PRO PRO LEU ASP ILE THR PRO TYR n/a n/a
6 1W0W - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
7 4G8I - LYS ARG TRP ILE ILE MET GLY LEU ASN LYS n/a n/a
8 5IND - GLN ALA SER GLN ASP VAL LYS ASN TRP n/a n/a
9 2BVP - ILE SER PRO ARG THR LEU ASP ALA TRP n/a n/a
10 6PYL - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
11 5V5L - THR SER THR LEU GLN GLU GLN ILE GLY TRP n/a n/a
12 5DEG - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
13 1UXS - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
14 3VRJ - LEU THR THR LYS LEU THR ASN THR ASN ILE n/a n/a
15 3BP4 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
16 3X12 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
17 6PYJ - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
18 6MTL - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
19 4O2C ic50 = 10 nM ACE SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
20 5WMP - THR PRO ARG VAL THR GLY GLY GLY ALA MET n/a n/a
21 5DEF - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
22 4U1M - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
23 5IM7 - GLN ALA SER GLN GLU VAL LYS ASN TRP n/a n/a
24 1A1N - VAL PRO LEU ARG PRO MET THR TYR n/a n/a
25 1OGT - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
26 3KPO - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
27 5WMR - GLN ILE LYS VAL ARG VAL ASP MET VAL n/a n/a
28 2A83 - ARG ARG ARG TRP HIS ARG TRP ARG LEU n/a n/a
29 6PYW - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
30 3B6S - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
31 1JGD - ARG ARG LEU LEU ARG GLY HIS ASN GLN TYR n/a n/a
32 5EO0 - ARG PRO MET THR PHE LYS GLY ALA LEU n/a n/a
33 1HSA - ALA ARG ALA ALA ALA ALA ALA ALA ALA n/a n/a
34 1AGE - GLY GLY LYS LYS LYS TYR ARG LEU n/a n/a
35 4JQV - SER GLU LEU GLU ILE LYS ARG TYR n/a n/a
36 3X11 - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
37 1M6O - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
38 6MT3 - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
39 4G9D - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
40 6BXP - ARG VAL LYS GLU LYS TYR GLN HIS LEU KYN n/a n/a
41 3LKR - LEU PRO PHE GLU ARG ALA THR VAL MET n/a n/a
42 3KPP - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
43 1K5N - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
44 6MT4 - PHE GLU ASP LEU ARG VAL SER SER PHE n/a n/a
45 4O2E - SER HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
46 4U1N - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
47 3BP7 - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
48 1XR9 - ILE LEU GLY PRO PRO GLY SER VAL TYR n/a n/a
49 5WMN - SER PRO ILE VAL PRO SER PHE ASP MET n/a n/a
50 1AGD - GLY GLY LYS LYS LYS TYR LYS LEU n/a n/a
51 3LKO - LEU PRO PHE ASP ARG THR THR ILE MET n/a n/a
52 1SYS - GLU GLU PRO THR VAL ILE LYS LYS TYR n/a n/a
53 3KPM - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
54 4U1S - PHE PRO ARG PRO TRP LEU HIS GLY LEU n/a n/a
55 4U1K - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
56 5U98 Kd = 0.2 nM VAL THR THR ASP ILE GLN VAL LYS VAL n/a n/a
57 2H6P - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
58 4XXC - ASP GLU LEU GLU ILE LYS ALA TYR n/a n/a
59 3UPR - HIS SER ILE THR TYR LEU LEU PRO VAL n/a n/a
60 4QRQ Kd = 2.48 uM HIS SER LYS LYS LYS CYS ASP GLU LEU n/a n/a
61 3X13 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
62 3VRI - ARG VAL ALA GLN LEU GLU GLN VAL TYR ILE n/a n/a
63 3LV3 - SER ARG ARG TRP ARG ARG TRP ASN ARG n/a n/a
64 1UXW - ARG ARG ARG TRP ARG ARG LEU THR VAL n/a n/a
65 1XR8 - LEU GLU LYS ALA ARG GLY SER THR TYR n/a n/a
66 1AGC - GLY GLY LYS LYS LYS TYR GLN LEU n/a n/a
67 5WMO - ARG PRO PRO ILE PHE ILE ARG ARG LEU n/a n/a
68 1A1M - THR PRO TYR ASP ILE ASN GLN MET LEU n/a n/a
69 4U1L - ARG PRO GLN VAL PRO LEU ARG PRO MET n/a n/a
70 3SKO - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
71 3BXN - ILE ARG ALA ALA PRO PRO PRO LEU PHE n/a n/a
72 1A1O - LYS PRO ILE VAL GLN TYR ASP ASN PHE n/a n/a
73 3DX7 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
74 6PZ5 - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
75 5W67 - VAL ARG SER ARG ARG ABA LEU ARG LEU n/a n/a
76 5EO1 - ARG PRO MET THR TYR LYS GLY ALA LEU n/a n/a
77 1M05 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
78 5TXS - ALA GLN ASP ILE TYR ARG ALA SER TYR n/a n/a
79 6PYV - LEU ARG ASN GLN SER VAL PHE ASN PHE n/a n/a
80 2BSR - ARG ARG ILE TYR ASP LEU ILE GLU LEU n/a n/a
81 5WMQ - GLU LEU ARG SER ARG TYR TRP ALA ILE n/a n/a
82 4QRS - GLU LEU LYS ARG LYS MET ILE TYR MET n/a n/a
83 2BST - SER ARG TYR TRP ALA ILE ARG THR ARG n/a n/a
84 4U1I - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
85 6BXQ - ARG VAL LYS GLU LYS TYR GLN HIS LEU TRP n/a n/a
86 6MT5 - PHE GLU ASP LEU ARG LEU LEU SER PHE n/a n/a
87 1AGB - GLY GLY ARG LYS LYS TYR LYS LEU n/a n/a
88 3LKQ - LEU PRO PHE ASP LYS THR THR ILE MET n/a n/a
89 2AXG - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
90 3DX6 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
91 1AGF - GLY GLY LYS LYS ARG TYR LYS LEU n/a n/a
92 2CIK - LYS PRO ILE VAL VAL LEU HIS GLY TYR n/a n/a
93 3LKN - LEU PRO PHE GLU ARG ALA THR ILE MET n/a n/a
94 2BSS - LYS ARG TRP ILE ILE LEU GLY LEU ASN LYS n/a n/a
95 3C9N - VAL GLN GLN GLU SER SER PHE VAL MET n/a n/a
96 4U1J - THR PRO GLN ASP LEU ASN THR MET LEU n/a n/a
97 3B3I - ARG ARG LYS TRP CIR ARG TRP HIS LEU n/a n/a
98 3DX8 - GLU GLU ASN LEU LEU ASP PHE VAL ARG PHE n/a n/a
99 3KPL - GLU GLU TYR LEU GLN ALA PHE THR TYR n/a n/a
100 5VGD - SER ALA GLU PRO VAL PRO LEU GLN LEU n/a n/a
101 1OF2 - ARG ARG LYS TRP ARG ARG TRP HIS LEU n/a n/a
102 1W0V - ARG ARG LEU PRO ILE PHE SER ARG LEU n/a n/a
103 1E27 - LEU PRO PRO VAL VAL ALA LYS GLU ILE n/a n/a
104 6MT6 - PHE GLU ASP LEU ARG VAL LEU SER PHE n/a n/a
105 1JGE - GLY ARG PHE ALA ALA ALA ILE ALA LYS n/a n/a
106 5T6W - SER SER THR ARG GLY ILE SER GLN LEU TRP n/a n/a
107 3X14 - PHE LEU ARG GLY ARG ALA TYR GLY LEU n/a n/a
108 1N2R - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
109 4QRU - GLU LEU ARG ARG LYS MET MET TYR MET n/a n/a
110 5W6A - ALA ARG THR GLU LEU TYR ARG SER LEU n/a n/a
111 2AXF - ALA PRO GLN PRO ALA PRO GLU ASN ALA TYR n/a n/a
112 4NT6 - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
113 3BWA - PHE PRO THR LYS ASP VAL ALA LEU n/a n/a
114 5T6X - THR SER THR THR SER VAL ALA SER SER TRP n/a n/a
115 4O2F - HIS VAL ALA VAL GLU ASN ALA LEU n/a n/a
116 3SKM - PHE LEU ARG GLY ARG ALA TYR VAL LEU n/a n/a
117 1SYV - GLU GLU PHE GLY ARG ALA PHE SER PHE n/a n/a
118 3KPQ - GLU GLU TYR LEU LYS ALA TRP THR PHE n/a n/a
119 3LKS - LEU PRO PHE GLU LYS SER THR VAL MET n/a n/a
120 1B0G - ALA LEU TRP GLY PHE PHE PRO VAL LEU n/a n/a
121 3GSW - ASN LEU VAL PRO MET VAL ALA ALA VAL n/a n/a
122 5HGA - ARG PHE PRO LEU THR PHE GLY TRP n/a n/a
123 2X4O - LYS LEU THR PRO LEU CYS VAL THR LEU n/a n/a
124 5N6B - LEU LEU TRP ASN GLY PRO MET ALA VAL n/a n/a
125 6PTE - ILE LEU ASN ALA MET ILE THR LYS ILE n/a n/a
126 1QR1 - ILE ILE SER ALA VAL VAL GLY ILE LEU n/a n/a
127 3O3B - GLU LEU ALA GIC 3AZ LEU THR VAL n/a n/a
128 5C0I - ARG GLN PHE GLY PRO ASP PHE PRO THR ILE n/a n/a
129 5N1Y - MET VAL TRP GLY PRO ASP PRO LEU TYR VAL n/a n/a
130 5GSD - SER SER CYS PRO LEU SER LYS n/a n/a
131 1I1Y - TYR LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
132 3FT3 ic50 = 44 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
133 2VLL - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
134 1T1Z - ALA LEU TYR ASN THR ALA ALA ALA LEU n/a n/a
135 3FQT - GLY LEU LEU GLY SER PRO VAL ARG ALA n/a n/a
136 3GSQ - ASN LEU VAL PRO SER VAL ALA THR VAL n/a n/a
137 4NQX - CYS THR GLU LEU LYS LEU ASN ASP TYR n/a n/a
138 6J1V - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
139 3VXN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
140 5C0J - ARG GLN PHE GLY PRO ASP TRP ILE VAL ALA n/a n/a
141 1DUZ - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
142 3H7B Kd = 41 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
143 3WL9 - ASN TYR THR PRO GLY PRO GLY ILE ARG PHE n/a n/a
144 4JFP - GLU LEU ALA ALA ILE GLY ILE LEU THR VAL n/a n/a
145 3FQW - ARG VAL ALA SER PRO THR SER GLY VAL n/a n/a
146 1TVB - ILE THR ASP GLN VAL PRO PHE SER VAL n/a n/a
147 1T1W - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
148 5C0F - ARG GLN TRP GLY PRO ASP PRO ALA ALA VAL n/a n/a
149 3MYJ - TYR MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
150 4WJ5 ic50 = 0.51 uM GRN NVA ALA GLY ILE GLY ILE LEU THR LPH n/a n/a
151 1Q94 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
152 3H9H Kd = 5.4 uM MET LEU TRP GLY TYR LEU GLN TYR VAL n/a n/a
153 3O3E - BAL LEU ALA TIG 3AZ LEU THR VAL n/a n/a
154 4I4W - ILE LEU ALA LYS PHE LEU HIS ARG LEU n/a n/a
155 2X4R - ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
156 4HWZ - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
157 3PWJ Kd = 70 uM LEU LEU TYR GLY PHE VAL ASN TYR VAL n/a n/a
158 3FQN - TYR LEU ASP SER GLY ILE HIS SER GLY ALA n/a n/a
159 3BHB ic50 = 3.4 nM LYS MET ASP SEP PHE LEU ASP MET GLN LEU n/a n/a
160 1S9W - SER LEU LEU MET TRP ILE THR GLN CYS n/a n/a
161 5C0G - TYR LEU GLY GLY PRO ASP PHE PRO THR ILE n/a n/a
162 4HX1 - SER VAL TYR ASP PHE PHE VAL TRP LEU n/a n/a
163 3MGO - ARG LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
164 1I7R - PHE ALA PRO GLY PHE PHE PRO TYR LEU n/a n/a
165 1X7Q - LYS THR PHE PRO PRO THR GLU PRO LYS n/a n/a
166 3WLB - ASN TYR THR PRO GLY PRO GLY THR ARG PHE n/a n/a
167 3RL2 - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
168 2GUO - ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
169 4JFQ - GLU LEU ALA GLY ILE GLY ILE ALA THR VAL n/a n/a
170 5EU4 - TYR LEU ALA PRO GLY PRO VAL THR ALA n/a n/a
171 1I7U - ALA LEU TRP GLY PHE VAL PRO VAL LEU n/a n/a
172 5C0D - ALA GLN TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
173 3GSO Kd = 27.7 uM ASN LEU VAL PRO MET VAL ALA THR VAL n/a n/a
174 3HPJ - ARG MET PHE PRO ASN ALA PRO TYR LEU n/a n/a
175 3KLA Kd = 31.1 uM SER LEU LEU MET TRP ILE THR GLN LEU n/a n/a
176 4K7F - VAL CYS TRP GLY GLU LEU MET ASN LEU n/a n/a
177 2V2W Kd = 2.2 uM SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
178 5SWQ - CYS VAL ASN GLY SER CYS PHE THR VAL n/a n/a
179 3I6L - GLN PHE LYS ASP ASN VAL ILE LEU LEU n/a n/a
180 1QVO - GLN VAL PRO LEU ARG PRO MET THR TYR LYS n/a n/a
181 2GIT - LEU LEU PHE GLY LYS PRO VAL TYR VAL n/a n/a
182 5EU5 - TYR LEU GLU PRO ALA PRO VAL THR ALA n/a n/a
183 2X70 - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
184 2GTZ - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
185 3OXR - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
186 1T1Y - SER LEU TYR ASN VAL VAL ALA THR LEU n/a n/a
187 1EEZ - ILE LEU SER ALA LEU VAL GLY ILE LEU n/a n/a
188 1TVH - ILE MET ASP GLN VAL PRO PHE SER VAL n/a n/a
189 6PTB - ILE LEU ASN ALA MET ILE ALA LYS ILE n/a n/a
190 3REW Kd = 28.8 uM CYS LEU GLY GLY LEU LEU THR MET VAL n/a n/a
191 5MEQ Kd = 28 uM ILE LEU ALA LYS PHE LEU HIS THR LEU n/a n/a
192 3I6G - GLY LEU MET TRP LEU SER TYR PHE VAL n/a n/a
193 5NMH - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
194 2C7U Kd = 100 nM SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
195 1EEY - ILE LEU SER ALA LEU VAL GLY ILE VAL n/a n/a
196 1HHJ - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
197 5HGB - ARG TYR PRO LEU THR PHE GLY TRP n/a n/a
198 6G3J - MET THR SER ALA ILE GLY ILE LEU PRO VAL n/a n/a
199 2GTW - LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
200 3GSV Kd = 57.5 uM ASN LEU VAL PRO GLN VAL ALA THR VAL n/a n/a
201 3D25 ic50 = 22 nM VAL LEU HIS ASP ASP LEU LEU GLU ALA n/a n/a
202 5EU3 - TYR LEU GLU PRO GLY PRO VAL THR ALA n/a n/a
203 3BH9 ic50 = 116.9 nM ARG THR TYR SEP GLY PRO MET ASN LYS VAL n/a n/a
204 3OXS - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
205 2V2X Kd = 5.2 uM SER LEU PHE ASN THR VAL ALA THR LEU n/a n/a
206 4JFO Kd = 140 uM ALA LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
207 5HHP - GLY ILE LEU GLU PHE VAL PHE THR LEU n/a n/a
208 4GKS - PHE LEU THR GLY ILE GLY ILE ILE THR VAL n/a n/a
209 1T20 - SER LEU TYR ASN THR ILE ALA THR LEU n/a n/a
210 3GIV - SER LEU PHE ASN THR VAL ALA THR LEU TYR n/a n/a
211 3VXP - ARG TYR PRO LEU THR LEU GLY TRP CYS PHE n/a n/a
212 3PWL Kd = 140 uM LEU GLY TYR GLY PHE VAL ASN TYR ILE n/a n/a
213 5NMK - SER LEU PHE ASN THR ILE ALA VAL LEU n/a n/a
214 6J2A - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
215 6J29 - GLN ILE MET TYR ASN TYR PRO ALA MET n/a n/a
216 5C0E - TYR GLN PHE GLY PRO ASP PHE PRO ILE ALA n/a n/a
217 3UTQ - ALA LEU TRP GLY PRO ASP PRO ALA ALA ALA n/a n/a
218 4F7P - PHE TYR ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
219 3RL1 - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
220 5HGH - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
221 3QFD Kd = 68 uM ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
222 3O3A - BAL LEU ALA GIC 3AZ LEU THR VAL n/a n/a
223 2X4N - LYS ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
224 4F7T - ARG TYR GLY PHE VAL ALA ASN PHE n/a n/a
225 5GRD - SER SER CYS SER SER CYS PRO LEU SER LYS n/a n/a
226 5MEO Kd = 1 uM ILE LEU GLY LYS PHE LEU HIS ARG LEU n/a n/a
227 3GSU Kd = 58.2 uM ASN LEU VAL PRO THR VAL ALA THR VAL n/a n/a
228 5HGD - ARG PHE PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
229 3IXA Kd = 9.8 uM LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
230 3FT2 ic50 = 44 nM VAL LEU CIR ASP ASP LEU LEU GLU ALA n/a n/a
231 2GT9 - GLU ALA ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
232 5MER - ILE LEU ALA LYS PHE LEU HIS GLU LEU n/a n/a
233 5HHN - GLY ILE LEU GLY LEU VAL PHE THR LEU n/a n/a
234 2CLR - MET LEU LEU SER VAL PRO LEU LEU LEU GLY n/a n/a
235 1T22 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
236 1I4F - GLY VAL TYR ASP GLY ARG GLU HIS THR VAL n/a n/a
237 3NFN - ARG TYR PRO LEU THR PHE GLY TRP CYS PHE n/a n/a
238 3FQU - GLY LEU LEU GLY SEP PRO VAL ARG ALA n/a n/a
239 1JF1 - GLU LEU ALA GLY ILE GLY ILE LEU THR VAL n/a n/a
240 1HHK - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
241 3BH8 ic50 = 11.2 nM ARG GLN ALA SEP ILE GLU LEU PRO SER MET n/a n/a
242 3BGM ic50 = 32.5 nM ARG GLN ALA SEP LEU SER ILE SER VAL n/a n/a
243 3O3D - GLU LEU ALA TIG 3AZ LEU THR VAL n/a n/a
244 3PWN Kd = 48 uM LEU LEU TYR GLY PHE VAL ASN TYR ILE n/a n/a
245 3MGT - LYS LEU TYR GLN ASN PRO THR THR TYR ILE n/a n/a
246 6OPD - ILE LEU ASN ALA MET ILE VAL LYS ILE n/a n/a
247 3FQX - ARG VAL ALA SEP PRO THR SER GLY VAL n/a n/a
248 1S9Y - SER LEU LEU MET TRP ILE THR GLN SER n/a n/a
249 2AV7 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
250 1S8D - SER LEU ALA ASN THR VAL ALA THR LEU n/a n/a
251 4F7M - LEU TYR ALA SER PRO GLN LEU GLU GLY PHE n/a n/a
252 6J1W - ALA ILE PHE GLN SER SER MET THR LYS n/a n/a
253 3OX8 - PHE LEU PRO SER ASP PHE PHE PRO SER VAL n/a n/a
254 3GSX - ASN LEU VAL PRO MET VAL ALA VAL VAL n/a n/a
255 1T1X - SER LEU TYR LEU THR VAL ALA THR LEU n/a n/a
256 1DUY - LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
257 1S9X - SER LEU LEU MET TRP ILE THR GLN ALA n/a n/a
258 2X4P - MSE ILE LEU GLY PRV VAL PHE PRQ VAL n/a n/a
259 3FT4 ic50 = 1171 nM VAL LEU ARG ASP ASP LEU LEU GLU ALA n/a n/a
260 1HHI - GLY ILE LEU GLY PHE VAL PHE THR LEU n/a n/a
261 1JHT - ALA LEU GLY ILE GLY ILE LEU THR VAL n/a n/a
262 2X4U - ILE LEU LYS GLU PRO VAL HIS GLY VAL n/a n/a
263 4NQV - CYS THR GLU LEU LYS LEU SER ASP TYR n/a n/a
264 5HHQ - GLY ILE TRP GLY PHE VAL PHE THR LEU n/a n/a
265 1T21 - SER LEU TYR ASN THR VAL ALA THR LEU n/a n/a
266 3BO8 - GLU ALA ASP PRO THR GLY HIS SER TYR n/a n/a
267 2AV1 - LEU LEU PHE GLY TYR PRO VAL TYR VAL n/a n/a
268 3GSR Kd = 60.2 uM ASN LEU VAL PRO VAL VAL ALA THR VAL n/a n/a
269 1QEW - PHE LEU TRP GLY PRO ARG ALA LEU VAL n/a n/a
270 1HSB - ALA VAL ALA n/a n/a
271 2HN7 ic50 = 31 nM ALA ILE MET PRO ALA ARG PHE TYR PRO LYS n/a n/a
272 3FQR - TYR LEU ASP SEP GLY ILE HIS SER GLY ALA n/a n/a
273 5GRG - SER SER CYS SER SER CYS n/a n/a
274 2RFX - LEU SER SER PRO VAL THR LYS SER PHE n/a n/a
275 5VCL - ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
276 3VJ6 Kd = 17 uM ALA MET ALA PRO ARG THR LEU LEU LEU n/a n/a
277 1WBZ - SER SER TYR ARG ARG PRO VAL GLY ILE n/a n/a
278 1VAD - SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
279 1FZM Kd = 20 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
280 4PV8 - ARG ABA PHE ILE PHE ALA ASN ILE n/a n/a
281 2ZSV - ARG ABA GLN ILE PHE ALA ASN ILE n/a n/a
282 2CLZ - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
283 1RK1 - SER GLU ILE GLU PHE ALA ARG LEU n/a n/a
284 3PAB Kd = 20 uM GLU ILE ILE ASN PHE GLU LYS LEU n/a n/a
285 1G7Q Kd = 877 nM SER ALA PRO ASP THR ARG PRO ALA n/a n/a
286 1FZO Kd = 13 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
287 4HS3 - ALA VAL TYR ASN PHE ALA THR MET n/a n/a
288 4PV9 - ARG ABA VAL ILE PHE ALA ASN ILE n/a n/a
289 1LEK Kd = 1.3 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
290 4PG9 - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
291 1NAN - ILE ASN PHE ASP PHE ASN THR ILE n/a n/a
292 2VAA - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
293 2VAB - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
294 2CLV - SER GLN TYR TYR TYR ASN SER LEU n/a n/a
295 1KJ3 - LYS VAL ILE THR PHE ILE ASP LEU n/a n/a
296 1RJY - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
297 1FZJ Kd = 8 nM ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
298 1G7P Kd = 90 nM SER ARG ASP HIS SER ARG THR PRO MET n/a n/a
299 1KPU - ARG GLY TYR VAL TYR GLN GLY LEU n/a n/a
300 1T0N - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
301 3P9L Kd = 6 uM SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
302 1T0M - SER SER ILE GLU PHE ALA ARG LEU n/a n/a
303 1FZK Kd = 4 nM PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
304 1KPV - PHE ALA PRO GLY ASN TYR PRO ALA LEU n/a n/a
305 1OSZ - ARG GLY TYR LEU TYR GLN GLY LEU n/a n/a
306 1LK2 ic50 = 12 uM GLY ASN TYR SER PHE TYR ALA LEU n/a n/a
307 1LEG Kd = 11.1 nM GLU GLN TYR LYS PHE TYR SER VAL n/a n/a
308 1KBG - ARG GLY TYR VAL TYR ESC GLY LEU GAL GLA n/a n/a
309 4PGE - PHE ALA PRO GLY ASN TYR PRO ALA TRP n/a n/a
310 6GB6 - GLY LEU n/a n/a
311 3P9M Kd = 10 uM SER ILE ILE GLY PHE GLU LYS LEU n/a n/a
312 1VAC - SER ILE ILE ASN PHE GLU LYS LEU n/a n/a
313 6IWG - MYR GLY GLY ALA ILE n/a n/a
314 6IWH - MYR GLY GLY GLY ILE n/a n/a
315 3PWU - ILE PRO ALA TYR GLY VAL LEU THR ILE n/a n/a
316 3CC5 - LYS VAL PRO ARG ASN GLN ASP TRP LEU n/a n/a
317 5MZM - MET CYS PRO ARG MET THR ALA VAL MET n/a n/a
318 4L8B - ALA SER ASN GLU HIS MET GLU THR MET n/a n/a
319 3CPL - ALA SER ASN GLU ASN ALA GLU THR MET n/a n/a
320 1WBY - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
321 3CH1 - GLU GLY PRO ARG ASN GLN ASP TRP LEU n/a n/a
322 4HV8 - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
323 1WBX - SER GLN LEU LYS ASN ASN ALA LYS GLU ILE n/a n/a
324 1YN7 - SER SER LEU GLU ASN PHE ALA ALA TYR VAL n/a n/a
325 1YN6 - SER SER LEU GLU ASN PHE ARG ALA TYR VAL n/a n/a
326 1JUF ic50 = 1400 nM SER SER VAL ILE GLY VAL TRP TYR LEU n/a n/a
327 1JPG - PHE GLN PRO GLN ASN GLY GLN PHE ILE n/a n/a
328 5E8O - MET ABA LEU ARG MET THR ALA VAL MET n/a n/a
329 1LD9 - TYR PRO ASN VAL ASN ILE HIS ASN PHE n/a n/a
330 5E8P - MET CYS LEU ARG NLE THR ALA VAL MET n/a n/a
331 1HOC - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
332 4HUX - ALA SER ASN GLU ASN MET GLU THR MET n/a n/a
333 4HUV - ALA SER ASN GLU ASN TRP GLU THR MET n/a n/a
334 1INQ ic50 = 539 nM SER SER VAL VAL GLY VAL TRP TYR LEU n/a n/a
335 2ZOK - ABA SER LEU TRP ASN GLY PRO HIS LEU n/a n/a
336 5E8N - MET CYS LEU ARG MET THR ALA VAL MET n/a n/a
337 4HUU - ALA SER ASN GLU ASN ILE GLU THR MET n/a n/a
338 4L8D - ALA SER ASN GLU ASP MET GLU THR MET n/a n/a
339 1S7Q - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
340 1S7T - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
341 6J2E - ASP PHE GLN GLU SER ALA ASP SER PHE LEU n/a n/a
342 6J2J - ASP PHE THR CYS SER GLN ILE SER PRO n/a n/a
343 6J2H - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
344 6K7T - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
345 6J2I - ASP PHE GLU LYS GLU GLY TYR SER LEU n/a n/a
346 4G43 - ILE ASP TRP PHE GLU GLY LYS GLU n/a n/a
347 4E0R - ILE ASP TRP PHE ASP GLY LYS GLU n/a n/a
348 4G42 - ILE ASP TRP PHE ASP GLY LYS ASP n/a n/a
349 4ZFZ Kd = 2.5 uM GLY GLY ALA ILE SER MYR n/a n/a
350 4CVZ - TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU n/a n/a
351 3RWG ic50 = 2.8 nM MET HIS PRO ALA GLN THR SER GLN TRP n/a n/a
352 3RWI ic50 = 116 nM GLY SER HIS LEU GLU VAL GLN GLY TYR TRP n/a n/a
353 3RWC ic50 = 7.6 nM ILE ARG TYR PRO LYS THR PHE GLY TRP n/a n/a
354 3RWE ic50 = 43 nM PHE GLN TRP MET GLY TYR GLU LEU TRP n/a n/a
355 1BII - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
356 3FOM - ILE GLN GLN SER ILE GLU ARG ILE n/a n/a
357 3FON - VAL ASN ASP ILE PHE GLU ALA ILE n/a n/a
358 5GSV - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
359 4WDI Kd = 286 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY n/a n/a
360 5GSR - TYR TYR SER ILE ALA PRO HIS SER ILE n/a n/a
361 5GR7 - TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
362 4Z78 Kd = 113 uM LEU TYR LEU VAL CYS GLY GLU ARG GLY PHE n/a n/a
363 4Z76 Kd = 13.6 uM LEU TYR LEU VAL CYS GLY GLU ARG VAL n/a n/a
364 5GSX - PHE TYR ALA PRO GLU PRO ILE THR SER LEU n/a n/a
365 5GSB - LYS TYR TYR SER ILE ILE PRO HIS SER ILE n/a n/a
366 3BZF - VAL MET ALA PRO ARG ALA LEU LEU LEU n/a n/a
367 6GH4 - ARG GLN PRO ALA LYS ALA PRO LEU LEU n/a n/a
368 6GH1 - ARG LEU PRO ALA LYS ALA PRO LEU LEU n/a n/a
369 3BZE - VAL MET ALA PRO ARG THR LEU PHE LEU n/a n/a
370 5H94 - LYS MET ASN THR GLN PHE THR ALA VAL n/a n/a
371 3QQ4 - ALA THR ALA ALA ALA THR GLU ALA TYR n/a n/a
372 5XS3 - VAL ARG SER ARG ARG CYS LEU ARG LEU n/a n/a
373 3ECB - ARG GLY PRO GLY ARG ALA PHE VAL THR ILE n/a n/a
374 5WEU Kd = 0.19 mM ARG GLY PRO GLY CYS ALA PHE VAL THR ILE n/a n/a
375 3E6F - ILE GLY PRO GLY ARG ALA PHE TYR ALA n/a n/a
376 5KD7 - ILE GLY PRO GLY ARG ALA PHE TYR VAL n/a n/a
377 3E6H - ILE GLY PRO GLY ARG ALA PHE TYR THR ILE n/a n/a
378 5T7G - ILE GLY PRO GLY ARG ALA PHE TYR THR n/a n/a
379 1MHC - FME TYR PHE ILE ASN ILE LEU THR LEU n/a n/a
380 6O9B - THR THR ALA PRO SER LEU SER GLY LYS n/a n/a
381 6O9C - THR THR ALA PRO PHE LEU SER GLY LYS n/a n/a
382 1ZT1 - PHE GLU ALA ASN GLY ASN LEU ILE n/a n/a
383 1K8D - ILE LEU MET GLU HIS ILE HIS LYS LEU n/a n/a
384 1KJM - ALA GLN PHE SER ALA SER ALA SER ARG n/a n/a
385 5J6H - NCA C6 H6 N2 O c1cc(cnc1)....
386 1KJV - ASN PRO ARG ALA MET GLN ALA LEU LEU n/a n/a
387 1YDP - ARG ILE ILE PRO ARG HIS LEU GLN LEU n/a n/a
388 3KYN - LYS GLY PRO PRO ALA ALA LEU THR LEU n/a n/a
389 3KYO - LYS LEU PRO ALA GLN PHE TYR ILE LEU n/a n/a
390 6J2F - ASP TYR ILE ASN THR ASN VAL LEU PRO n/a n/a
391 6J2D - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
392 6ILC - ASP PHE ALA ASN THR PHE LEU PRO n/a n/a
393 1S7X - LYS ALA VAL PHE ASN PHE ALA THR MET n/a n/a
394 6GB5 - PHE ALA PRO GLY ASN TYR PRO n/a n/a
395 6GB7 - GLU ASP ALA GLY GLY GLY GLY LEU SER LYS n/a n/a
396 1S7U - LYS ALA VAL TYR ASN PHE ALA THR MET n/a n/a
397 1S7V - LYS ALA VAL TYR ASN LEU ALA THR MET n/a n/a
398 1S7W - LYS ALA LEU TYR ASN PHE ALA THR MET n/a n/a
399 1TMC - GLU VAL ALA PRO PRO GLU TYR HIS ARG LYS n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: LEU SER SER PRO VAL THR LYS SER PHE; Similar ligands found: 124
No: Ligand ECFP6 Tc MDL keys Tc
1 LEU SER SER PRO VAL THR LYS SER PHE 1 1
2 LEU PRO PHE GLU LYS SER THR VAL MET 0.586667 0.909091
3 ARG VAL SER PRO SER THR SER TYR THR PRO 0.560606 0.920635
4 LEU PRO PHE ASP LYS SER THR ILE MET 0.55414 0.895522
5 PHE PRO THR LYS ASP VAL ALA LEU 0.554054 0.951613
6 PRO LYS ARG PRO THR THR LEU ASN LEU PHE 0.546584 0.855072
7 GLY TYR GLU ASN PRO THR TYR LYS PHE PHE 0.544872 0.823529
8 VAL ORN LEU DPN PRO VAL ORN LEU DPN PRO 0.542857 0.84127
9 LEU ASN PHE PRO ILE SER PRO 0.521739 0.907692
10 LYS THR PHE PRO PRO THR GLU PRO LYS 0.52 0.904762
11 SER THR SEP PRO THR PHE ASN LYS 0.515924 0.84058
12 MAA LYS PRO PHE 0.515385 0.819672
13 LEU PRO PHE ASP LYS THR THR ILE MET 0.509554 0.880597
14 SER SER CYS PRO LEU SER LYS 0.507463 0.934426
15 ACE GLY PHE GLY VAL VAL PRO SER PHE TYR 0.5 0.873016
16 ASN PHE ASP ASN PRO VAL TYR ARG LYS THR 0.497041 0.783784
17 LEU PRO SER PHE GLU THR ALA LEU 0.496644 0.951613
18 GLY GLN VAL PRO PHE SER LYS GLU GLU CYS 0.490323 0.90625
19 ALA ASN SER ARG PHE PRO THR SER ILE ILE 0.484472 0.828571
20 PHE LEU SER THR LYS 0.480916 0.8
21 GLN LEU SER PRO PHE PRO PHE ASP LEU 0.480263 0.892308
22 ARG SEP PRO VAL PHE SER 0.477419 0.777778
23 LEU PHE GLY TYR PRO VAL TYR VAL 0.476821 0.80597
24 PHE TYR ALA PRO GLU PRO ILE THR SER LEU 0.475309 0.869565
25 ARG THR PHE SER PRO THR TYR GLY LEU 0.475309 0.808219
26 GLY SER ASP PRO PHE LYS 0.47482 0.887097
27 LYS LEU TYR GLN ASN PRO THR THR TYR ILE 0.472393 0.867647
28 GLY ARG PRO ARG THR THR SER PHE ALA GLU 0.472393 0.852941
29 PHE LEU PRO SER ASP PHE PHE PRO SER VAL 0.469799 0.907692
30 GLU GLU PRO THR VAL ILE LYS LYS TYR 0.46875 0.878788
31 ASN TRP SER HIS PRO GLN PHE GLU LYS 0.468531 0.818182
32 ILE THR ASP GLN VAL PRO PHE SER VAL 0.468354 0.936508
33 ARG ARG LEU PRO ILE PHE SER ARG LEU 0.468354 0.867647
34 LEU LEU PHE GLY TYR PRO VAL TYR VAL 0.467949 0.80597
35 LEU LEU PHE GLY PHE PRO VAL TYR VAL 0.467949 0.80597
36 LEU LEU PHE GLY LYS PRO VAL TYR VAL 0.465409 0.782609
37 ARG PRO MET THR PHE LYS GLY ALA LEU 0.465116 0.794521
38 LYS PRO VAL LEU ARG THR ALA 0.463087 0.835821
39 SER ASP ILE LEU PHE PRO ALA ASP SER 0.46 0.920635
40 GLY THR SER SER PRO SER ALA ASP 0.455882 0.870968
41 THR THR ALA PRO PHE LEU SER GLY LYS 0.45283 0.936508
42 TYR LEU GLU PRO ALA PRO VAL THR ALA 0.45098 0.878788
43 SER TYR SEP PRO THR SEP PRO SEP TYR SER 0.449664 0.8
44 LEU PRO LYS MYK THR GLY GLY 0.448718 0.875
45 THR PRO PRO SER PRO PHE 0.447761 0.903226
46 LEU TYR ALA SER PRO GLN LEU GLU GLY PHE 0.446429 0.850746
47 ALA THR PRO PHE GLN GLU 0.445312 0.883333
48 LEU PRO PHE GLU ARG ALA THR VAL MET 0.444444 0.805556
49 ALA PHE ARG ILE PRO LEU THR ARG 0.44375 0.867647
50 ARG ARG ARG GLU ARG SER PRO THR ARG 0.443709 0.808824
51 PRO THR SEP PRO SER TYR 0.443709 0.814286
52 PHE ASN PHE PRO GLN ILE THR 0.443709 0.848485
53 LEU PRO PRO VAL VAL ALA LYS GLU ILE 0.441558 0.8125
54 ALA ASN SER ARG TRP PRO THR THR ARG LEU 0.441176 0.821918
55 PHE SER ALA PTR PRO SER GLU GLU ASP 0.440789 0.777778
56 GLU LEU PRO PRO VAL LYS ILE HIS CYS 0.439306 0.779412
57 LYS LEU THR PRO LEU CYS VAL THR LEU 0.439189 0.919355
58 LYS GLN GLU PRO GLN GLU ILE ASP PHE 0.438272 0.84127
59 1IP CYS PHE SER LYS PRO ARG 0.438272 0.788732
60 HIS HIS ALA SER PRO ARG LYS 0.434783 0.757143
61 GLU LYS PRO SER SER SER 0.432836 0.854839
62 TYR LEU LYS GLU PRO VAL HIS GLY VAL 0.432749 0.797101
63 TYR PRO SER LYS PRO ASP ASN PRO GLY GLU 0.432624 0.888889
64 DPN PRO DAR DTH NH2 0.432624 0.818182
65 GLU LEU PRO LEU VAL LYS ILE 0.432432 0.809524
66 ARG ILE PRO SER TYR ARG TYR ARG TYR 0.432258 0.819444
67 LEU PRO PHE ASP ARG THR THR ILE MET 0.431953 0.808219
68 TYR LEU GLU PRO GLY PRO VAL THR VAL 0.43125 0.907692
69 TYR LEU GLU PRO GLY PRO VAL THR ALA 0.43125 0.907692
70 ILE ARG TYR PRO LYS THR PHE GLY TRP 0.430851 0.75
71 LYS PRO PHE PTR VAL ASN VAL NH2 0.428571 0.756757
72 PBE PRO LYS THR SER GLY LYS ALA ALA 0.427586 0.852941
73 LYS LEU PRO ALA GLN PHE TYR ILE LEU 0.426035 0.808824
74 PHE ASN ARG PRO VAL 0.425676 0.768116
75 GLN VAL PRO LEU ARG PRO MET THR TYR LYS 0.425414 0.786667
76 SER SER GLY LYS VAL PRO LEU SER 0.424658 0.919355
77 ARG TYR PRO LEU THR PHE GLY TRP CYS PHE 0.424084 0.786667
78 ILE SER PRO ARG THR LEU ASP ALA TRP 0.423077 0.821918
79 ARG PRO GLY ASN PHE LEU GLN SER ARG LEU 0.422857 0.867647
80 VAL MET ALA PRO ARG THR LEU PHE LEU 0.422619 0.805556
81 HIS SER ILE THR TYR LEU LEU PRO VAL 0.422619 0.869565
82 ALA ASN SER ARG TYR PRO THR SER ILE ILE 0.421687 0.794521
83 SER THR GLY GLY VAL M3L LYS PRO HIS ARG 0.421622 0.776316
84 LYS PRO PHE PTR VAL ASN VAL GLU PHE 0.421053 0.746667
85 TYR PRO LYS ARG ILE ALA 0.420382 0.760563
86 ALA ILE MET PRO ALA ARG PHE TYR PRO LYS 0.41989 0.714286
87 ASP PHE GLU GLU ILE PRO GLU GLU TYS 0.419753 0.650602
88 ILE LEU LYS GLU PRO VAL HIS GLY VAL 0.419162 0.776119
89 PRO ALA PRO PHE ALA SER ALA 0.418919 0.903226
90 SER SER TYR ARG ARG PRO VAL GLY ILE 0.418182 0.84507
91 LEU VAL THR LEU VAL PHE VAL 0.41791 0.65
92 SER PRO ILE VAL PRO SER PHE ASP MET 0.417178 0.867647
93 SER SER GLY LYS VAL PRO LEU 0.416667 0.903226
94 TYR LEU ALA PRO GLY PRO VAL THR ALA 0.416667 0.893939
95 ARG LEU TYR GLN ASN PRO THR THR TYR ILE 0.416185 0.797297
96 LYS LEU LEU PHE 0.416 0.666667
97 LYS PRO ILE VAL GLN TYR ASP ASN PHE 0.415205 0.84058
98 LEU PRO PHE GLU ARG ALA THR ILE MET 0.414773 0.794521
99 ARG GLN PHE GLY PRO ASP PHE PRO THR ILE 0.414773 0.805556
100 SER PRO LYS ARG ILE ALA 0.413793 0.779412
101 ARG PRO MET THR TYR LYS GLY ALA LEU 0.413408 0.763158
102 ILE MET ASP GLN VAL PRO PHE SER VAL 0.413174 0.865672
103 SER MET PRO GLU LEU SER PRO VAL LEU 0.412162 0.850746
104 ARG PRO PRO GLY PHE SER PRO PHE ALA 0.412121 0.785714
105 GLY GLY CYS PHE SER LYS PRO LYS MYR 0.411765 0.863636
106 GLN VAL PRO SER ASP PRO TYR ASN TYR 0.411392 0.893939
107 LEU GLN ARG VAL LEU SEP ALA PRO PHE 0.411043 0.756757
108 THR PRO ARG ARG SER MLZ SER ALA 0.410959 0.814286
109 VAL SER GLN ASN TYR PRO ILE VAL GLN ASN 0.408805 0.893939
110 TYR SEP PRO THR SEP PRO SER 0.408163 0.802817
111 PHE LEU PRO HIS ALY TYR ASP VAL LYS LEU 0.407821 0.785714
112 ARG PHE PRO LEU THR PHE GLY TRP 0.407821 0.794521
113 ASN ASP LYS TYR GLU PRO PHE TRP GLU 0.407609 0.771429
114 VAL PRO LEU ARG PRO MET THR TYR 0.407186 0.797297
115 GLY LEU LEU GLY SER PRO VAL ARG ALA 0.406452 0.794118
116 PKF 0.406452 0.710526
117 PHE SER GLN HIS LYS THR SER TPO ILE 0.405882 0.716216
118 SER ILE TYR PHE TPO PRO GLU LEU TYR ASP 0.404494 0.786667
119 ARG PRO GLY ASN PHE LEU GLN SER ARG PRO 0.403409 0.842857
120 GLU PHE SER PRO 0.402985 0.83871
121 ASN GLY TYR GLU ASN PRO THR TYR LYS 0.402367 0.823529
122 TYR LEU GLY GLY PRO ASP PHE PRO THR ILE 0.402299 0.867647
123 ALA ASN SER ARG TRP PRO THR SER ALY ILE 0.4 0.776316
124 ARG VAL ALA SER PRO THR SER GLY VAL 0.4 0.823529
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2RFX; Ligand: LEU SER SER PRO VAL THR LYS SER PHE; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2rfx.bio1) has 28 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback