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Receptor
PDB id Resolution Class Description Source Keywords
2RIF 2.35 Å NON-ENZYME: OTHER CBS DOMAIN PROTEIN PAE2072 FROM PYROBACULUM AEROPHILUM COMPL AMP PYROBACULUM AEROPHILUM CBS DOMAIN BATEMAN DOMAIN AMP BINDING PROTEIN TRANSFERASEBINDING PROTEIN
Ref.: STRUCTURES AND FUNCTIONAL IMPLICATIONS OF AN AMP-BI CYSTATHIONINE BETA-SYNTHASE DOMAIN PROTEIN FROM A HYPERTHERMOPHILIC ARCHAEON. J.MOL.BIOL. V. 380 181 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
AMP A:201;
A:301;
B:201;
B:301;
C:201;
C:301;
D:201;
D:301;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
347.221 C10 H14 N5 O7 P c1nc(...
CS A:139;
A:140;
B:139;
B:140;
B:141;
B:142;
C:139;
C:140;
C:141;
D:139;
D:140;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
132.905 Cs [Cs+]
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2RIF 2.35 Å NON-ENZYME: OTHER CBS DOMAIN PROTEIN PAE2072 FROM PYROBACULUM AEROPHILUM COMPL AMP PYROBACULUM AEROPHILUM CBS DOMAIN BATEMAN DOMAIN AMP BINDING PROTEIN TRANSFERASEBINDING PROTEIN
Ref.: STRUCTURES AND FUNCTIONAL IMPLICATIONS OF AN AMP-BI CYSTATHIONINE BETA-SYNTHASE DOMAIN PROTEIN FROM A HYPERTHERMOPHILIC ARCHAEON. J.MOL.BIOL. V. 380 181 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1443 families.
1 2RIF - AMP C10 H14 N5 O7 P c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1205 families.
1 2RIF - AMP C10 H14 N5 O7 P c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1039 families.
1 2RIF - AMP C10 H14 N5 O7 P c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: AMP; Similar ligands found: 395
No: Ligand ECFP6 Tc MDL keys Tc
1 A 1 1
2 AMP 1 1
3 A2D 0.833333 0.943662
4 ABM 0.833333 0.943662
5 ADP 0.823529 0.971429
6 A12 0.808824 0.931507
7 AP2 0.808824 0.931507
8 BA3 0.808824 0.943662
9 SRA 0.80303 0.944444
10 AP5 0.797101 0.943662
11 B4P 0.797101 0.943662
12 HEJ 0.788732 0.971429
13 ATP 0.788732 0.971429
14 AT4 0.785714 0.931507
15 AN2 0.785714 0.957747
16 5FA 0.777778 0.971429
17 AQP 0.777778 0.971429
18 APC 0.777778 0.931507
19 CA0 0.774648 0.917808
20 M33 0.774648 0.930556
21 AU1 0.774648 0.944444
22 ADX 0.774648 0.848101
23 ACP 0.763889 0.944444
24 50T 0.763889 0.957747
25 25A 0.75641 0.971429
26 AR6 0.753425 0.943662
27 PRX 0.753425 0.917808
28 APR 0.753425 0.943662
29 ACQ 0.746667 0.944444
30 T99 0.746667 0.931507
31 TAT 0.746667 0.931507
32 SAP 0.743243 0.918919
33 AD9 0.743243 0.944444
34 AGS 0.743243 0.918919
35 RBY 0.743243 0.905405
36 ADV 0.743243 0.905405
37 ANP 0.723684 0.944444
38 ADP PO3 0.72 0.942857
39 6YZ 0.717949 0.944444
40 5AL 0.714286 0.930556
41 SON 0.712329 0.931507
42 LMS 0.710145 0.825
43 RAB 0.709677 0.842857
44 XYA 0.709677 0.842857
45 ADN 0.709677 0.842857
46 ATF 0.705128 0.931507
47 GAP 0.701299 0.891892
48 A22 0.7 0.957747
49 SRP 0.696203 0.905405
50 7D5 0.691176 0.902778
51 A3P 0.684932 0.971014
52 A2P 0.684932 0.956522
53 ADP ALF 0.683544 0.868421
54 ALF ADP 0.683544 0.868421
55 ADQ 0.682927 0.917808
56 MAP 0.679012 0.918919
57 ADP VO4 0.675 0.930556
58 VO4 ADP 0.675 0.930556
59 OOB 0.670732 0.930556
60 9ZA 0.670732 0.906667
61 8QN 0.670732 0.930556
62 5SV 0.670732 0.87013
63 9ZD 0.670732 0.906667
64 PTJ 0.670588 0.894737
65 AOC 0.666667 0.84507
66 PAJ 0.662651 0.858974
67 4AD 0.662651 0.893333
68 A3R 0.662651 0.881579
69 A1R 0.662651 0.881579
70 AMO 0.662651 0.905405
71 5N5 0.661538 0.816901
72 DAL AMP 0.658537 0.90411
73 IMO 0.657534 0.928571
74 AHX 0.654762 0.87013
75 00A 0.654762 0.881579
76 DLL 0.654762 0.930556
77 5AS 0.653333 0.776471
78 A4D 0.651515 0.816901
79 5CD 0.651515 0.828571
80 9X8 0.647059 0.893333
81 OAD 0.647059 0.917808
82 3UK 0.647059 0.917808
83 ADP BMA 0.647059 0.891892
84 25L 0.643678 0.957747
85 PR8 0.639535 0.848101
86 WAQ 0.639535 0.881579
87 LAD 0.639535 0.858974
88 B5V 0.639535 0.905405
89 DTA 0.637681 0.808219
90 V3L 0.6375 0.971429
91 3DH 0.633803 0.794521
92 BIS 0.632184 0.906667
93 ME8 0.632184 0.8375
94 3OD 0.632184 0.917808
95 FYA 0.632184 0.930556
96 NB8 0.632184 0.87013
97 1ZZ 0.632184 0.8375
98 TXA 0.632184 0.905405
99 MTA 0.628571 0.794521
100 3AM 0.625 0.956522
101 EP4 0.623188 0.773333
102 A A 0.62069 0.971429
103 9SN 0.617977 0.87013
104 M2T 0.614286 0.753247
105 JB6 0.613636 0.881579
106 YAP 0.611111 0.893333
107 B5Y 0.611111 0.893333
108 FA5 0.611111 0.905405
109 B5M 0.611111 0.893333
110 MYR AMP 0.606742 0.814815
111 G5A 0.604938 0.776471
112 XAH 0.604396 0.8375
113 4UV 0.597826 0.893333
114 71V 0.597403 0.906667
115 ATP A A A 0.593407 0.929577
116 PAP 0.592593 0.957143
117 G3A 0.591398 0.894737
118 2AM 0.589041 0.942857
119 5X8 0.5875 0.783784
120 6RE 0.586667 0.779221
121 6C6 0.585366 0.905405
122 AFH 0.585106 0.858974
123 4UU 0.585106 0.893333
124 G5P 0.585106 0.894737
125 GA7 0.585106 0.905405
126 7D3 0.584416 0.878378
127 A5A 0.583333 0.804878
128 TSB 0.581395 0.795181
129 AMP DBH 0.580645 0.891892
130 TYR AMP 0.580645 0.868421
131 2A5 0.580247 0.891892
132 DQV 0.578947 0.930556
133 DSH 0.578947 0.74359
134 GTA 0.578947 0.860759
135 TAD 0.578947 0.858974
136 6IA 0.578313 0.858974
137 SSA 0.576471 0.776471
138 AMZ 0.575342 0.888889
139 C2R 0.575342 0.876712
140 PGS 0.575 0.857143
141 7D4 0.575 0.878378
142 ZAS 0.573333 0.786667
143 ATR 0.573171 0.942857
144 LAQ 0.572917 0.8375
145 AAM 0.571429 1
146 J7C 0.571429 0.789474
147 A3N 0.571429 0.783784
148 PPS 0.571429 0.848101
149 AIR 0.571429 0.927536
150 52H 0.569767 0.776471
151 54H 0.569767 0.785714
152 VMS 0.569767 0.785714
153 AR6 AR6 0.568421 0.916667
154 ARG AMP 0.568421 0.82716
155 7MD 0.568421 0.8375
156 YLP 0.56701 0.817073
157 48N 0.56701 0.87013
158 OVE 0.565789 0.90411
159 UPA 0.565657 0.881579
160 2SA 0.564706 0.905405
161 S4M 0.564103 0.682353
162 5CA 0.563218 0.776471
163 53H 0.563218 0.776471
164 8X1 0.563218 0.75
165 UP5 0.561224 0.893333
166 NAI 0.561224 0.881579
167 6V0 0.561224 0.87013
168 NAX 0.561224 0.848101
169 4UW 0.561224 0.858974
170 DND 0.561224 0.905405
171 TXD 0.561224 0.881579
172 NXX 0.561224 0.905405
173 NIA 0.56 0.820513
174 D5M 0.558442 0.902778
175 DA 0.558442 0.902778
176 MAO 0.556962 0.777778
177 AHZ 0.556701 0.814815
178 OMR 0.555556 0.82716
179 ITT 0.555556 0.915493
180 TYM 0.555556 0.905405
181 TXE 0.555556 0.881579
182 5AD 0.552239 0.768116
183 A2R 0.551724 0.957747
184 LPA AMP 0.55102 0.814815
185 DSZ 0.550562 0.776471
186 NSS 0.550562 0.776471
187 LSS 0.550562 0.758621
188 AP0 0.55 0.87013
189 YLC 0.55 0.8375
190 4TC 0.55 0.87013
191 YLB 0.55 0.817073
192 P5A 0.549451 0.741573
193 139 0.54902 0.848101
194 A4P 0.544554 0.819277
195 NVA LMS 0.544444 0.75
196 GJV 0.544304 0.769231
197 7D7 0.544118 0.763889
198 9K8 0.543478 0.711111
199 A7D 0.54321 0.797297
200 AF3 ADP 3PG 0.54 0.835443
201 6K6 0.539326 0.957143
202 IOT 0.539216 0.829268
203 A3G 0.538462 0.797297
204 LEU LMS 0.538462 0.75
205 A5D 0.535714 0.808219
206 7MC 0.534653 0.817073
207 T5A 0.533981 0.817073
208 ADJ 0.533981 0.82716
209 YLA 0.533981 0.817073
210 GSU 0.532609 0.776471
211 KAA 0.532609 0.75
212 7RA 0.531646 0.985507
213 SFG 0.53012 0.77027
214 SAH 0.529412 0.763158
215 HFD 0.529412 0.918919
216 AYB 0.528846 0.807229
217 CNA 0.528846 0.905405
218 N6P 0.527473 0.942029
219 8BR 0.525 0.931507
220 F2R 0.52381 0.839506
221 80F 0.523364 0.817073
222 Y3J 0.521127 0.746479
223 YSA 0.520833 0.776471
224 7RP 0.518987 0.955882
225 BTX 0.518868 0.839506
226 NAD 0.518868 0.930556
227 COD 0.518868 0.788235
228 G A A A 0.518868 0.87013
229 MHZ 0.518072 0.714286
230 SA8 0.517647 0.725
231 6AD 0.517241 0.883117
232 DZD 0.514019 0.858974
233 BT5 0.514019 0.829268
234 RMB 0.5125 0.898551
235 SAI 0.511628 0.753247
236 AV2 0.511364 0.890411
237 8PZ 0.510417 0.776471
238 A3D 0.509259 0.917808
239 A3S 0.506024 0.808219
240 3AT 0.505747 0.943662
241 SAM 0.505747 0.707317
242 SMM 0.505618 0.702381
243 NA7 0.505376 0.931507
244 4TA 0.504673 0.804878
245 AMP NAD 0.504673 0.90411
246 EEM 0.5 0.707317
247 G 0.5 0.905405
248 NEC 0.5 0.743243
249 5GP 0.5 0.905405
250 AAT 0.5 0.725
251 YLY 0.495495 0.807229
252 M24 0.495495 0.848101
253 7C5 0.494949 0.815789
254 DAT 0.494118 0.878378
255 A3T 0.494118 0.819444
256 P2P 0.493827 0.928571
257 FAI 0.493827 0.888889
258 1RB 0.493671 0.911765
259 NAE 0.491071 0.893333
260 U A 0.490909 0.906667
261 NAJ PZO 0.490909 0.846154
262 A G 0.490741 0.881579
263 TM1 0.489583 0.771084
264 A A A 0.489362 0.90411
265 A6D 0.489362 0.740741
266 PO4 PO4 A A A A PO4 0.489362 0.901408
267 S7M 0.488889 0.707317
268 DTP 0.488636 0.878378
269 RBZ 0.4875 0.873239
270 101 0.4875 0.902778
271 EAD 0.486957 0.848101
272 NAQ 0.486726 0.87013
273 U A G G 0.486239 0.881579
274 4YB 0.485149 0.758621
275 NDE 0.483051 0.931507
276 ZID 0.482456 0.917808
277 N0B 0.482456 0.817073
278 WSA 0.480769 0.785714
279 RGT 0.479592 0.931507
280 ARU 0.478723 0.835443
281 GGZ 0.478261 0.8
282 JLN 0.47561 0.863014
283 ANZ 0.475248 0.820513
284 QQY 0.475 0.837838
285 ACK 0.475 0.885714
286 NAJ PYZ 0.473684 0.804878
287 S8M 0.473118 0.779221
288 GEK 0.473118 0.734177
289 AVV 0.473118 0.87013
290 3AD 0.472973 0.828571
291 A U 0.471698 0.868421
292 P1H 0.470588 0.82716
293 0UM 0.468085 0.716049
294 RVP 0.467532 0.847222
295 649 0.466667 0.741573
296 Z5A 0.465517 0.776471
297 PMO 0.464286 0.873239
298 SXZ 0.463918 0.707317
299 62X 0.463158 0.682353
300 QQX 0.4625 0.826667
301 8Q2 0.462264 0.75
302 2VA 0.45977 0.797297
303 IMP 0.458824 0.90411
304 K15 0.458333 0.698795
305 CC5 0.458333 0.84058
306 AS 0.457831 0.855263
307 DDS 0.455556 0.851351
308 V1N 0.455446 0.943662
309 NJP 0.454545 0.918919
310 7DD 0.453488 0.957143
311 93A 0.453488 0.804878
312 G7M 0.453488 0.87013
313 3L1 0.453333 0.77027
314 3D1 0.453333 0.77027
315 EO7 0.452381 0.785714
316 NDC 0.45082 0.87013
317 FB0 0.45082 0.781609
318 0WD 0.45045 0.894737
319 NVA 2AD 0.449438 0.75641
320 26A 0.447368 0.76
321 2FA 0.447368 0.810811
322 2BA 0.447059 0.914286
323 CMP 0.447059 0.927536
324 D3Y 0.446809 0.786667
325 KB1 0.444444 0.716049
326 APU 0.444444 0.893333
327 VRT 0.444444 0.766234
328 SO8 0.444444 0.786667
329 FDA 0.443548 0.809524
330 PUA 0.443478 0.858974
331 ODP 0.441441 0.883117
332 6FA 0.44 0.817073
333 103 0.439024 0.861111
334 RP1 0.439024 0.864865
335 SP1 0.439024 0.864865
336 3NZ 0.438776 0.779221
337 A C A C 0.438596 0.846154
338 7DT 0.438202 0.957143
339 NDP 0.436364 0.894737
340 NPW 0.436364 0.860759
341 MTP 0.434211 0.727273
342 FAS 0.433071 0.82716
343 SFD 0.433071 0.712766
344 FAD 0.433071 0.82716
345 IRN 0.432432 0.867647
346 ZZB 0.432432 0.792683
347 TXP 0.432432 0.894737
348 NZQ 0.432432 0.883117
349 62F 0.430769 0.8375
350 FNK 0.430769 0.781609
351 128 0.429907 0.752941
352 1DA 0.428571 0.842857
353 6MD 0.428571 0.805556
354 PAX 0.428571 0.82716
355 SLU 0.426087 0.767442
356 XNP 0.424779 0.848101
357 12D 0.424528 0.761905
358 5F1 0.423077 0.72973
359 ETB 0.422414 0.809524
360 DCA 0.422414 0.8
361 F0P 0.422018 0.725
362 WMP 0.421053 0.864865
363 GUO 0.421053 0.864865
364 FAY 0.416667 0.8375
365 38Y 0.415929 0.804878
366 5J9 0.415842 0.728395
367 COA 0.415254 0.8
368 0T1 0.415254 0.8
369 KH3 0.415094 0.690476
370 U A C C 0.413793 0.857143
371 N01 0.413793 0.90411
372 FMP 0.413793 0.871429
373 RFL 0.413534 0.797619
374 NMN AMP PO4 0.412281 0.868421
375 GP2 0.408602 0.858974
376 GDP 0.408602 0.893333
377 NAP 0.408333 0.944444
378 NOC 0.407895 0.760563
379 2ER 0.405941 0.831169
380 1PR 0.405941 0.820513
381 P5F 0.405797 0.8
382 CAO 0.404959 0.772727
383 TAP 0.404959 0.906667
384 30N 0.404959 0.731183
385 COS 0.404959 0.781609
386 AMX 0.404959 0.809524
387 XMP 0.402299 0.891892
388 G2P 0.402062 0.858974
389 APC G U 0.401709 0.833333
390 U A A U 0.401639 0.906667
391 CMX 0.401639 0.8
392 NA0 0.401639 0.931507
393 SCO 0.401639 0.8
394 9JJ 0.40146 0.8375
395 F2N 0.4 0.790698
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 70
This union binding pocket(no: 1) in the query (biounit: 2rif.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 4UUU SAM None
2 1LNX URI None
3 5WHT SIA None
4 5WHT SIA GAL GLC None
5 1RL4 BL5 None
6 5WHT SIA GAL None
7 5TDC NMM ILE PHE SER None
8 3COW 52H 2.12766
9 4KBA 1QM 2.12766
10 4CNK MEU 2.12766
11 1P6O HPY 3.5461
12 1XTT U5P 3.5461
13 4QLX KTC 3.5461
14 4QLX FMN 3.5461
15 1N4K I3P 4.25532
16 3BMN AX3 4.25532
17 6AYU MLI 4.25532
18 4PQG NAG 4.25532
19 4FWE FAD 4.96454
20 3KP6 SAL 4.96454
21 2AJH MET 5.67376
22 3ITA AIC 5.67376
23 1I1E DM2 5.67376
24 3VOZ 04A 6.38298
25 2Q37 3AL 6.38298
26 3W5N RAM 6.38298
27 4YH2 GSH 6.38298
28 4Z24 FAD 6.38298
29 6C8X BVR 7.07071
30 5YZ2 AMP 7.0922
31 5WJ6 B4A 7.0922
32 3B2Q AES 7.0922
33 4GUT FAD 7.25806
34 4HSU FAD 7.25806
35 4GUS FAD 7.25806
36 1PVC ILE SER GLU VAL 7.80142
37 3QDL FMN 7.80142
38 4LY9 S6P 7.80142
39 4LY9 1YY 7.80142
40 5A89 FMN 8.51064
41 5A89 ADP 8.51064
42 5Z75 NAD 8.51064
43 2PNZ 5GP 9.92908
44 4AGS GSH 9.92908
45 5CLO NS8 10.1695
46 1YQC GLV 10.6383
47 3FW3 GLC 10.6383
48 3DUV KDO 10.6383
49 1HFE CYS 11.3475
50 5A7Y SAH 12.0567
51 5WQP NCA 12.0567
52 2GK6 ADP 12.766
53 4Z87 GDP 13.4752
54 2UV4 AMP 14.8936
55 2QRD ATP 15.6028
56 2QRD ADP 15.6028
57 3HRD NIO 16.3121
58 4CYI ATP 16.3121
59 1JPA ANP 19.1489
60 3L2B B4P 19.8582
61 2X3F APC 20.5674
62 2V92 ATP 21.2766
63 2Y8L ADP 21.2766
64 2V92 AMP 21.2766
65 2Y8L AMP 21.2766
66 3NB0 G6P 23.4043
67 2BNE U5P 24.8227
68 3TDH AMP 26.2411
69 3KH5 ADP 44.6809
70 3KH5 AMP 44.6809
Pocket No.: 2; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 38
This union binding pocket(no: 2) in the query (biounit: 2rif.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 5LOL GSH None
2 5GZ9 ANP None
3 4J1Q NDP None
4 4ITU NAI None
5 5FFF NAP 1.41844
6 3KO8 NAD 2.83688
7 2PZM NAD 2.83688
8 2PZM UDP 2.83688
9 3PMA SCR 3.5461
10 1Q19 APC 3.5461
11 1ORR NAD 3.5461
12 2JB2 FAD 4.25532
13 2JB2 PHE 4.25532
14 2WTX VDO 4.25532
15 2WTX UDP 4.25532
16 2DTX BMA 4.25532
17 2BGM NAJ 4.25532
18 5O96 SAM 4.25532
19 3LXK MI1 4.96454
20 4JWJ SAH 5.67376
21 1XKQ NDP 6.38298
22 6CI9 NAP 7.0922
23 2V6K TGG 7.0922
24 5K4W NAI 7.80142
25 5K4W THR 7.80142
26 2CJF RP4 7.80142
27 1W6U NAP 8.51064
28 5L3R GCP 9.21986
29 5XWV NDP 12.0567
30 5L3S GNP 12.766
31 2V58 LZJ 13.4752
32 1BXK NAD 13.4752
33 4ZS4 ATP 14.1844
34 2XB8 XNW 14.1844
35 1W8D NAP 18.4397
36 1W73 NAP 18.4397
37 4D5G FAD 24.8227
38 4D5G TPP 24.8227
Pocket No.: 3; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 184
This union binding pocket(no: 3) in the query (biounit: 2rif.bio2) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1RE8 BD2 None
2 5MY8 RXZ None
3 4ARU TLA None
4 5AWM ANP None
5 5NLD LBT None
6 1TQP ATP None
7 4WB7 ATP None
8 2XK9 XK9 None
9 1JQY A32 None
10 4WB6 ATP None
11 1Z83 AP5 None
12 1R2Q GNP None
13 1TU3 GNP None
14 4NZN 2OU 1.41844
15 4NZN ANP 1.41844
16 4NFE BEN 1.41844
17 1AKY AP5 1.41844
18 4B7X NAP 1.41844
19 3ORQ ADP 2.12766
20 3FHI ANP 2.12766
21 2VBU CDP 2.20588
22 3KMW ATP 2.32558
23 6F3G CJN 2.37288
24 1OBD AMP 2.83688
25 1CM8 ANP 2.83688
26 2PUL ACP 2.83688
27 4Q5H ANP 2.83688
28 5LYH 7B8 2.83688
29 3IDB ANP 2.83688
30 5GM1 SAH 2.83688
31 3BL7 DD1 2.83688
32 5J60 FAD 2.83688
33 4DC2 ADE 2.83688
34 1ZX5 LFR 2.83688
35 3VRY B43 2.83688
36 1J09 GLU 3.5461
37 1J09 ATP 3.5461
38 4Y8D 49J 3.5461
39 5H2U 1N1 3.5461
40 3T1A 5MA 3.5461
41 1YID ATP 3.5461
42 1VQ2 DDN 3.5461
43 1NJJ GET 3.5461
44 1W2D 4IP 3.5461
45 5ENZ UDP 3.5461
46 4YHQ G10 4.0404
47 1CBK ROI 4.25532
48 5MW8 ATP 4.25532
49 5HGZ MLA 4.25532
50 4NTD FAD 4.25532
51 3WBF NAP 4.25532
52 4ANP 3QI 4.25532
53 5VCV 1N1 4.25532
54 5TDF ADP 4.25532
55 5YF9 NIO 4.25532
56 6A1G 9OL 4.25532
57 5OES ADP 4.25532
58 1PHK ATP 4.25532
59 2QF7 AGS 4.25532
60 3RE4 TO1 4.25532
61 2Z49 AMG 4.96454
62 3VPB ADP 4.96454
63 3VPC ADP 4.96454
64 1O9U ADZ 4.96454
65 5DK4 ATP 4.96454
66 5DK4 5BX 4.96454
67 4XYM A12 4.96454
68 1GVE NAP 4.96454
69 5HVJ ANP 4.96454
70 2WU6 DKI 4.96454
71 2QCS ANP 4.96454
72 4IEN COA 4.96454
73 5O1I 9GH 4.96454
74 3KV4 OGA 4.96454
75 4X60 3XV 4.96454
76 4X60 SFG 4.96454
77 5F90 LMR 4.96454
78 2Z48 A2G 4.96454
79 2CSN CKI 4.96454
80 4RDH AMP 4.96454
81 2R3A SAM 4.96454
82 4NJH SAM 5.67376
83 4NJH 2K8 5.67376
84 5Z21 NAI 5.67376
85 2BP1 NDP 5.67376
86 2QX0 PH2 5.67376
87 3C6K MTA 5.67376
88 3C6K SPD 5.67376
89 4OCV ANP 5.67376
90 4G6I RS3 5.67376
91 1IA9 ANP 5.67376
92 4LRJ ANP 5.67376
93 5VZ0 ADP 5.67376
94 1JBU BEN 6.38298
95 6CGD GNP 6.38298
96 6CGD AKN 6.38298
97 4A4X JUP 6.38298
98 2MBR FAD 6.38298
99 2BKK ADP 6.38298
100 3TM0 B31 6.38298
101 3TM0 ANP 6.38298
102 3PVW QRX 6.38298
103 5YK1 ANP 6.38298
104 5T67 JHZ 6.38298
105 5T67 SAH 6.38298
106 5CEO 50D 6.38298
107 2IO8 ADP 6.38298
108 1ZDQ MSM 6.38298
109 3A6T 8OG 6.97674
110 6AC9 ANP 7.0922
111 3DLS ADP 7.0922
112 3GC8 B45 7.0922
113 2PYW ADP 7.0922
114 4K38 SAM 7.0922
115 5N5U AMP 7.0922
116 4K37 SAM 7.0922
117 5AX9 4KT 7.0922
118 2VQD AP2 7.80142
119 3HKW IX6 7.80142
120 2PVN P63 7.80142
121 2Z3H BLO 8.46154
122 3WO0 ADP 8.51064
123 3WO0 ALA 8.51064
124 2PZI AXX 8.51064
125 1N62 MCN 8.51064
126 5EFQ ADP 8.51064
127 4NST ADP 8.51064
128 2C91 NAP 8.51064
129 5UY8 AMZ 8.51064
130 4LOO SB4 8.51064
131 3X01 AMP 9.21986
132 4EN4 GT0 9.21986
133 4EN4 ATP 9.21986
134 4EN4 GT1 9.21986
135 3ZOA ACR 9.21986
136 5HQ0 LZ9 9.21986
137 3RHZ UDP 9.92908
138 4YNM SAM 9.92908
139 3GNI ATP 9.92908
140 4FMU 0UM 9.92908
141 1Y57 MPZ 9.92908
142 2WET FAD 9.92908
143 4G17 0VN 9.92908
144 2JFQ DGL 9.92908
145 4XV1 904 9.92908
146 1J71 THR ILE THR SER 10.6383
147 2VPQ ANP 10.6383
148 4USF 6UI 10.6383
149 2YIV YIV 10.6383
150 5T8O 76Z 10.6383
151 3ALN ANP 10.6383
152 1T36 ADP 11.3475
153 4F4P 0SB 11.3475
154 1XF1 CIT 11.3475
155 4NM5 ADP 11.3475
156 4E93 GUI 11.3475
157 4Y0X ADP 12.0567
158 3VPD ANP 12.0567
159 6CQF F97 12.0567
160 3PFD FDA 12.0567
161 5TWJ SAM 12.0567
162 4XZ3 ACP 12.0567
163 4H3Q ANP 12.0567
164 4GYI ADP 12.766
165 5ZCT ANP 12.766
166 2EWM NAD 13.4752
167 4OH4 ANP 13.4752
168 1IOW PHY 13.4752
169 1IOW ADP 13.4752
170 6FL8 ADP 14.1844
171 6FL8 TIY 14.1844
172 2BMB PMM 14.1844
173 3UDZ ADP 14.1844
174 3VOT ADP 15.6028
175 6BFN DL1 16.3121
176 2DWU DGL 17.7305
177 4XGX ADP 17.7305
178 2Y6O 1N1 18.4397
179 5MJA 7O3 19.1489
180 1GSA ADP 19.8582
181 5C1P ADP 25.5319
182 4CNG SAH 25.5319
183 5C1P DAL DAL 25.5319
184 5O98 NAP 34.0426
Pocket No.: 4; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 48
This union binding pocket(no: 4) in the query (biounit: 2rif.bio2) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 1JQI FAD None
2 1SIV PSI None
3 2HK5 1BM None
4 1IDA 0PO None
5 4WHZ 3NL 2.12766
6 6GR0 F8W 2.12766
7 5W4W 9WG 2.12766
8 1EGD FAD 3.5461
9 1UDY FAD 3.5461
10 1UDY CS8 3.5461
11 2OBF SAH 3.5461
12 3SZB I1E 3.5461
13 5EW0 3C7 3.5461
14 5YS9 FAD 3.5461
15 3PP0 03Q 3.5461
16 3CEV ARG 4.25532
17 1RX0 FAD 4.25532
18 2HQM FAD 4.25532
19 1GPE FAD 4.25532
20 5Y9D FAD 4.25532
21 3LXD FAD 4.25532
22 4EWH T77 4.25532
23 5WGR FAD 4.96454
24 4RDI ATP 4.96454
25 6ES0 BW8 4.96454
26 4D79 ATP 4.96454
27 1JG0 UMP 5.67376
28 5FYR INS 5.67376
29 2GZM DGL 6.38298
30 3A7R LAQ 7.0922
31 1SG4 CO8 7.0922
32 3E1T FAD 7.80142
33 5E1M PRO PRO LYS ARG ILE ALA 7.80142
34 5E1M SAH 7.80142
35 3FSY SCA 9.33735
36 1UKG MMA 9.92908
37 5OOH NAP 10.6383
38 5OOH 9ZZ 10.6383
39 3HW5 AMP 11.3475
40 1ZUW DGL 12.0567
41 3H0A D30 13.4752
42 1PCA CIT 14.8936
43 2XVD AS6 19.1489
44 4RVG TYD 21.9858
45 4L6T GAL NGA GAL BGC SIA 24.8227
46 4YMJ 4EJ 24.8227
47 2OFV 242 24.8227
48 2F5Z FAD 29.6875
Pocket No.: 5; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 21
This union binding pocket(no: 5) in the query (biounit: 2rif.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 5DQ8 FLF None
2 2YAB AMP 2.12766
3 4OCJ NDG 2.83688
4 4MIG G3F 4.25532
5 4JR7 GNP 4.25532
6 6AMI TRP 5.67376
7 5KO1 6UY 6.38298
8 2PWY SAH 7.0922
9 2ZOF BES 7.0922
10 4MIB 28M 7.80142
11 4K26 SFF 8.51064
12 5Y6Q MCN 8.51064
13 2RIO ADP 9.92908
14 1Q8V MAN MAN 9.92908
15 5N53 8NB 10.6383
16 3LAD FAD 11.3475
17 4ZOH MCN 12.0567
18 6CMJ F6J 14.1844
19 4AT3 LTI 14.8936
20 5USZ SKE 16.3121
21 2XI7 XI7 17.9348
Pocket No.: 6; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 39
This union binding pocket(no: 6) in the query (biounit: 2rif.bio1) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 2AE2 NAP None
2 2AE2 PTO None
3 3G5D 1N1 None
4 4D42 W0I None
5 4D42 NAP None
6 4ITU 1HS None
7 5BVE 4VG 2.12766
8 5XDT MB3 2.12766
9 5UIU 8CG 2.16718
10 3VC1 GST 2.83688
11 2OBF F83 3.5461
12 1W2D ADP 3.5461
13 4CQM NAP 4.25532
14 2Z48 NGA 4.96454
15 1XSE NDP 4.96454
16 3VPB GLU 4.96454
17 5TTJ FAD 6.38298
18 1JNR FAD 7.0922
19 1N7G NDP 7.0922
20 5MLR GRQ 8.51064
21 5U5G NAP 9.21986
22 3V4S ATP 9.92908
23 3V4S ADP 9.92908
24 3K5I ADP 11.3475
25 3K5I AIR 11.3475
26 5XWV 8H6 12.0567
27 5OLK DTP 12.0567
28 3HB5 NAP 13.4752
29 3AY6 BGC 14.1844
30 3AY6 NAI 14.1844
31 4GLW 0XT 14.8936
32 3RNM FAD 16.3121
33 3ETH ATP 18.4397
34 2VVM FAD 19.1489
35 1KZL CRM 21.9858
36 3SJU NDP 22.695
37 3VZS CAA 23.4043
38 3VZS NAP 23.4043
39 2A8X FAD 34.7518
Pocket No.: 7; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 13
This union binding pocket(no: 7) in the query (biounit: 2rif.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1EQ2 ADQ None
2 1V2A GTS 2.83688
3 3VSV XYP 4.96454
4 4FC7 NAP 4.96454
5 4FC7 COA 4.96454
6 5IGL BMF 4.96454
7 4O8A 2OP 6.38298
8 2IO8 CYS 6.38298
9 3BFF FPM 7.0922
10 3WD6 GSH 7.80142
11 4URF NAD 7.80142
12 1RJ9 GCP 9.53947
13 5AE2 FAD 10.6383
Pocket No.: 8; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 13
This union binding pocket(no: 8) in the query (biounit: 2rif.bio1) has 16 residues
No: Leader PDB Ligand Sequence Similarity
1 4RHS SIA SIA GAL None
2 2XG5 EC2 1.41844
3 2XG5 EC5 1.41844
4 2AG5 NAD 3.5461
5 2D24 XYS XYS 4.96454
6 2ZA5 2FF 4.96454
7 1DNP FAD 4.96454
8 2UUU PL3 5.67376
9 2UUU FAD 5.67376
10 2KCE D16 5.67376
11 6EMU SAM 6.38298
12 6GCB GSH 7.80142
13 2CDC XYS 9.21986
Pocket No.: 9; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 11
This union binding pocket(no: 9) in the query (biounit: 2rif.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 4JLS 3ZE None
2 5BUK FAD 2.12766
3 2IF8 ADP 2.12766
4 2XKO AKG 2.83688
5 2ZV2 609 4.96454
6 5Y86 HRM 5.67376
7 1V59 FAD 5.67376
8 2VN9 GVD 9.21986
9 5BVA FAD 13.4752
10 1PG4 COA 14.1844
11 1PG4 PRX 14.1844
Pocket No.: 10; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 10) in the query (biounit: 2rif.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 11; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 11) in the query (biounit: 2rif.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 12; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 12) in the query (biounit: 2rif.bio3) has 15 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 13; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 13) in the query (biounit: 2rif.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 14; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 14) in the query (biounit: 2rif.bio3) has 16 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 15; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 15) in the query (biounit: 2rif.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 16; Query (leader) PDB : 2RIF; Ligand: AMP; Similar sites found with APoc: 2
This union binding pocket(no: 16) in the query (biounit: 2rif.bio3) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 1QKQ MAN 2.12766
2 5OFW 9TW 10.6383
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