Receptor
PDB id Resolution Class Description Source Keywords
2UUS 2.2 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE RAT FGF1-SUCROSE OCTASULFATE (SOS) RATTUS NORVEGICUS DIFFERENTIATION HEPARIN-BINDING SUCROSE OCTASULFATE DEVELPROTEIN FIBROBLAST GROWTH FACTOR MITOGEN ANGIOGENESIS GFACTOR
Ref.: DIMERIZATION EFFECT OF SUCROSE OCTASULFATE ON RAT F ACTA CRYSTALLOGR.,SECT.F V. 64 448 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GU4 YYJ C:1;
Valid;
none;
submit data
974.737 n/a S(=O)...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3K1X 1.98 Å NON-ENZYME: BINDING ACIDIC FIBROBLAST GROWTH FACTOR (FGF-1) COMPLEXED WITH DOBES HOMO SAPIENS ACIDIC FIBROBLAST GROWTH FACTOR INHIBITORS ACETYLATION HO
Ref.: GENTISIC ACID, A COMPOUND ASSOCIATED WITH PLANT DEF A METABOLITE OF ASPIRIN, HEADS A NEW CLASS OF IN VI FIBROBLAST GROWTH FACTOR INHIBITORS. J.BIOL.CHEM. V. 285 11714 2010
Members (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 552 families.
1 3JUT - GTQ C7 H6 O4 c1cc(c(cc1....
2 1HKN - N2M C10 H9 N O3 S c1cc2cc(cc....
3 2UUS - GU4 YYJ n/a n/a
4 3K1X - DBX C6 H6 O5 S c1cc(c(cc1....
70% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 426 families.
1 3JUT - GTQ C7 H6 O4 c1cc(c(cc1....
2 1HKN - N2M C10 H9 N O3 S c1cc2cc(cc....
3 2UUS - GU4 YYJ n/a n/a
4 3K1X - DBX C6 H6 O5 S c1cc(c(cc1....
50% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 3JUT - GTQ C7 H6 O4 c1cc(c(cc1....
2 1HKN - N2M C10 H9 N O3 S c1cc2cc(cc....
3 2UUS - GU4 YYJ n/a n/a
4 3K1X - DBX C6 H6 O5 S c1cc(c(cc1....
5 1BFC - SGN IDS SGN IDS SGN UAP n/a n/a
6 1BFB - SGN IDS SGN UAP n/a n/a
7 4OEE Kd = 1.73 uM IDY GNX n/a n/a
8 4OEG Kd = 9.01 uM IDY SUS n/a n/a
9 4OEF Kd = 17.5 uM IDY SGN n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: GU4 YYJ; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 GU4 YYJ 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: GU4 YYJ; Similar ligands found: 0
No: Ligand Similarity coefficient
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3K1X; Ligand: DBX; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3k1x.bio2) has 7 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 3K1X; Ligand: DBX; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 3k1x.bio1) has 7 residues
No: Leader PDB Ligand Sequence Similarity
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