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Receptor
PDB id Resolution Class Description Source Keywords
2VDV 2.3 Å EC: 2.1.1.33 STRUCTURE OF TRM8, M7G METHYLATION ENZYME SACCHAROMYCES CEREVISIAE S-ADENOSYL-L-METHIONINE PHOSPHORYLATION METHYLTRANSFERASE M7G TRNA SPOUT MT TRANSFERASE TRNA PROCESSING
Ref.: STRUCTURE OF THE YEAST TRNA M7G METHYLATION COMPLEX. STRUCTURE V. 16 52 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM E:1287;
F:1287;
Valid;
Valid;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2VDV 2.3 Å EC: 2.1.1.33 STRUCTURE OF TRM8, M7G METHYLATION ENZYME SACCHAROMYCES CEREVISIAE S-ADENOSYL-L-METHIONINE PHOSPHORYLATION METHYLTRANSFERASE M7G TRNA SPOUT MT TRANSFERASE TRNA PROCESSING
Ref.: STRUCTURE OF THE YEAST TRNA M7G METHYLATION COMPLEX. STRUCTURE V. 16 52 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2VDV - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2VDV - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2VDV - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 202
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 ADN 0.565789 0.773333
9 RAB 0.565789 0.773333
10 XYA 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 5AL 0.510417 0.743902
25 54H 0.510204 0.673913
26 VMS 0.510204 0.673913
27 0UM 0.51 0.857143
28 AMP 0.505747 0.707317
29 LMS 0.505747 0.666667
30 A 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 SON 0.5 0.746988
34 SSA 0.5 0.684783
35 6RE 0.5 0.78481
36 K15 0.5 0.883117
37 5AD 0.5 0.75
38 SRP 0.5 0.746988
39 LSS 0.49505 0.706522
40 CA0 0.494624 0.714286
41 A12 0.494505 0.705882
42 AP2 0.494505 0.705882
43 ME8 0.490385 0.841463
44 TSB 0.49 0.681319
45 53H 0.49 0.666667
46 DAL AMP 0.49 0.765432
47 5CA 0.49 0.684783
48 ACP 0.489362 0.694118
49 ADP 0.48913 0.690476
50 5AS 0.48913 0.648936
51 J7C 0.488889 0.772152
52 A2D 0.488889 0.690476
53 ZAS 0.488636 0.769231
54 9ZD 0.485149 0.729412
55 9ZA 0.485149 0.729412
56 8QN 0.485149 0.743902
57 GAP 0.484536 0.73494
58 AN2 0.483871 0.682353
59 A3S 0.483871 0.813333
60 A7D 0.483871 0.851351
61 GJV 0.483516 0.775
62 SRA 0.483146 0.694118
63 LAD 0.480769 0.752941
64 KAA 0.480769 0.698925
65 GSU 0.480769 0.722222
66 AMO 0.480392 0.746988
67 DSZ 0.480392 0.703297
68 52H 0.48 0.666667
69 M33 0.478723 0.722892
70 BA3 0.478261 0.690476
71 MAO 0.478261 0.82716
72 NEC 0.477778 0.75
73 AOC 0.477778 0.776316
74 DSH 0.477778 0.842105
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 NVA LMS 0.475728 0.736264
78 Y3J 0.47561 0.706667
79 G5A 0.474227 0.684783
80 A3T 0.473684 0.8
81 B4P 0.473118 0.690476
82 AP5 0.473118 0.690476
83 A3N 0.472527 0.766234
84 KB1 0.471698 0.833333
85 PRX 0.46875 0.73494
86 APC 0.46875 0.705882
87 AT4 0.468085 0.686047
88 PAJ 0.466019 0.712644
89 4AD 0.466019 0.759036
90 RBY 0.463918 0.72619
91 ADP PO3 0.463918 0.728395
92 ADV 0.463918 0.72619
93 ADX 0.463158 0.666667
94 MHZ 0.463158 0.82716
95 AU1 0.463158 0.674419
96 YAP 0.462963 0.738095
97 TXA 0.462264 0.72619
98 NB8 0.462264 0.72093
99 A3G 0.461538 0.802632
100 VRT 0.459184 0.842105
101 XAH 0.458716 0.715909
102 YSA 0.458716 0.684783
103 HEJ 0.458333 0.690476
104 50T 0.458333 0.682353
105 ATP 0.458333 0.690476
106 LEU LMS 0.457143 0.717391
107 7D7 0.45679 0.723684
108 KH3 0.455357 0.871795
109 ACQ 0.454545 0.694118
110 AR6 0.453608 0.710843
111 APR 0.453608 0.710843
112 AQP 0.453608 0.690476
113 5FA 0.453608 0.690476
114 NSS 0.451923 0.703297
115 FA5 0.449541 0.746988
116 A5D 0.44898 0.789474
117 AD9 0.44898 0.674419
118 AGS 0.44898 0.678161
119 SAP 0.44898 0.678161
120 PTJ 0.448598 0.72093
121 YLB 0.448276 0.758621
122 YLP 0.447368 0.738636
123 8X1 0.446602 0.680851
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 3AM 0.444444 0.674699
128 MYR AMP 0.444444 0.776471
129 OAD 0.443396 0.73494
130 2VA 0.443299 0.779221
131 S8M 0.442308 0.831169
132 OOB 0.442308 0.722892
133 TYR AMP 0.441441 0.759036
134 6YZ 0.441176 0.694118
135 ADP VO4 0.441176 0.702381
136 VO4 ADP 0.441176 0.702381
137 T99 0.44 0.686047
138 TAT 0.44 0.686047
139 ANP 0.44 0.674419
140 WAQ 0.439252 0.75
141 B5Y 0.436364 0.717647
142 8PZ 0.436364 0.684783
143 F0P 0.435897 0.844156
144 YLC 0.435897 0.755814
145 AAT 0.435644 0.797468
146 1ZZ 0.435185 0.755814
147 9K8 0.435185 0.663158
148 3OD 0.435185 0.73494
149 NVA 2AD 0.434343 0.855263
150 00A 0.433962 0.689655
151 DLL 0.433962 0.722892
152 ARG AMP 0.433628 0.727273
153 7MD 0.433628 0.715909
154 ATF 0.431373 0.666667
155 SO8 0.43 0.792208
156 3UK 0.429907 0.714286
157 A6D 0.429907 0.72619
158 9X8 0.429907 0.717647
159 F2R 0.429752 0.7
160 5SV 0.428571 0.741176
161 AMP DBH 0.428571 0.714286
162 TYM 0.42735 0.746988
163 WSA 0.42735 0.692308
164 9SN 0.427273 0.681818
165 AHZ 0.426087 0.755814
166 P5A 0.425926 0.691489
167 B5V 0.425926 0.705882
168 PR8 0.425926 0.744186
169 A A 0.425926 0.710843
170 3NZ 0.425926 0.807692
171 A1R 0.424528 0.709302
172 2A5 0.424242 0.674419
173 7MC 0.423729 0.719101
174 B5M 0.423423 0.717647
175 7D5 0.422222 0.658824
176 JB6 0.422018 0.709302
177 FYA 0.422018 0.722892
178 AYB 0.421488 0.75
179 A22 0.419048 0.682353
180 MAP 0.419048 0.659091
181 2AM 0.417582 0.666667
182 TAD 0.417391 0.712644
183 A3P 0.416667 0.686747
184 ADP BMA 0.416667 0.714286
185 25A 0.415094 0.690476
186 YLA 0.413223 0.719101
187 8Q2 0.411765 0.663158
188 A3R 0.411215 0.709302
189 ADQ 0.411215 0.694118
190 48N 0.410256 0.72093
191 0XU 0.41 0.824324
192 GA7 0.408696 0.72619
193 7D3 0.40625 0.643678
194 PAP 0.405941 0.678571
195 DQV 0.405172 0.702381
196 OVE 0.404255 0.662791
197 4UV 0.403509 0.697674
198 AF3 ADP 3PG 0.403361 0.712644
199 3AD 0.402299 0.783784
200 CMP 0.402062 0.691358
201 2BA 0.402062 0.682927
202 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2VDV; Ligand: SAM; Similar sites found with APoc: 974
This union binding pocket(no: 1) in the query (biounit: 2vdv.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1EDO NAP None
2 5WUW NAP None
3 2CHT TSA None
4 3U4C NDP 0.813008
5 5FEU NAP 0.813008
6 5FFF 5XC 0.813008
7 1GY8 NAD 0.813008
8 5FFF NAP 0.813008
9 2JAH NDP 0.813008
10 5O4J 9KH 1.09489
11 5O4J PJL 1.09489
12 5O4J SAH 1.09489
13 1FP1 SAH 1.21951
14 4ITU NAI 1.21951
15 4ITU 1HS 1.21951
16 1G0N NDP 1.21951
17 1G0N PHH 1.21951
18 6F9Q NAD 1.21951
19 1NFQ NAI 1.21951
20 4MCC 21X 1.21951
21 3P2E SAH 1.33333
22 1NW5 SAM 1.62602
23 1XHC FAD 1.62602
24 2EWM NAD 1.62602
25 1EK6 NAI 1.62602
26 1EK6 UPG 1.62602
27 2Q0L FAD 1.62602
28 2JHP SAH 1.62602
29 2QBU SAH 1.72414
30 1TE2 PGA 1.76991
31 3G2O SAM 2.03252
32 4A6D SAM 2.03252
33 2NXE SAM 2.03252
34 6GAS FAD 2.03252
35 4TM3 FAD 2.03252
36 3AB1 FAD 2.03252
37 2YG3 FAD 2.03252
38 5MBX FAD 2.03252
39 5MBX SP5 2.03252
40 5JCM ISD 2.03252
41 5JCM NAD 2.03252
42 5JCM FAD 2.03252
43 5J60 FAD 2.03252
44 2GDZ NAD 2.03252
45 2Q46 NAP 2.03252
46 1GZ6 NAI 2.03252
47 5X68 FAD 2.03252
48 3KO8 NAD 2.03252
49 3TN7 NJP 2.03252
50 5OJI ISN 2.03252
51 5OJI NAP 2.03252
52 5XLX SAH 2.03252
53 2JAP NDP 2.03252
54 1KYQ NAD 2.03252
55 4O1M NAD 2.03252
56 1C0I FAD 2.03252
57 1C0I BE2 2.03252
58 3OND ADN 2.03252
59 3OND NAD 2.03252
60 1FUR MLT 2.03252
61 5L13 6ZE 2.03252
62 1UP7 NAD 2.03252
63 4XT8 NAP 2.03252
64 4WZ8 3W7 2.03252
65 4LZB URA 2.10084
66 1O5O U5P 2.26244
67 2DTX BMA 2.27273
68 4NTD FAD 2.35294
69 4X60 3XV 2.43902
70 4X60 SFG 2.43902
71 5UFN SAH 2.43902
72 4KRG SAH 2.43902
73 2ZIF SAM 2.43902
74 4N49 SAM 2.43902
75 4UCI SAM 2.43902
76 2A14 SAH 2.43902
77 4B63 ORN 2.43902
78 4B63 FAD 2.43902
79 4B63 NAP 2.43902
80 4OPC FDA 2.43902
81 4OPC PGT 2.43902
82 1PN0 FAD 2.43902
83 1PN0 IPH 2.43902
84 5TWB FAD 2.43902
85 4BJZ FAD 2.43902
86 4BJZ P3A 2.43902
87 1ZQ9 SAM 2.43902
88 4CNK FAD 2.43902
89 1XHL NDP 2.43902
90 3MAG SAH 2.43902
91 3UOY FAD 2.43902
92 3UOY NAP 2.43902
93 1V5F TPP 2.43902
94 1V5F FAD 2.43902
95 3MCT SAH 2.43902
96 3SJU NDP 2.43902
97 2RH4 EMO 2.43902
98 1FEC FAD 2.43902
99 3OID NDP 2.43902
100 1XG5 NAP 2.43902
101 3F8D FAD 2.43902
102 1XSE NDP 2.43902
103 3A28 NAD 2.43902
104 3RFV 15L 2.43902
105 3RFV NAI 2.43902
106 3AFN NAP 2.43902
107 5ZI9 FLC 2.43902
108 4EIP FAD 2.43902
109 4D42 NAP 2.43902
110 4D42 W0I 2.43902
111 4OM8 NAD 2.43902
112 3W9F I3P 2.43902
113 1MXH DHF 2.43902
114 5JE8 NAD 2.43902
115 1MXH NAP 2.43902
116 4Q9N NAI 2.43902
117 4U7W NDP 2.43902
118 1O5I NAD 2.43902
119 1P3D UMA 2.43902
120 1VL0 NAI 2.43902
121 1IM8 SAI 2.45902
122 1Q7B NAP 2.45902
123 4NBT NAD 2.5
124 1E1M NAP 2.6087
125 1E1M FAD 2.6087
126 4CS9 AMP 2.6455
127 3FSY SCA 2.71084
128 4IWN GEK 2.84553
129 3LCV SAM 2.84553
130 3L9W AMP 2.84553
131 1XTP SAI 2.84553
132 2DPM SAM 2.84553
133 3L9W GSH 2.84553
134 1KYZ SAH 2.84553
135 1KYZ FER 2.84553
136 2JB2 PHE 2.84553
137 2JB2 FAD 2.84553
138 1YXM ADE 2.84553
139 5O42 BGC 2.84553
140 5O42 9JW 2.84553
141 5O42 NAD 2.84553
142 1ZEM NAD 2.84553
143 5K4W NAI 2.84553
144 5J5Z FAD 2.84553
145 5K4W THR 2.84553
146 3E1T FAD 2.84553
147 1IY8 NAD 2.84553
148 6F97 FAD 2.84553
149 1RP0 AHZ 2.84553
150 3LAD FAD 2.84553
151 3GDN HBX 2.84553
152 3GDN FAD 2.84553
153 4NBU NAI 2.84553
154 1GEG NAD 2.84553
155 3QWI CUE 2.84553
156 3QWI NAP 2.84553
157 5OC1 FAD 2.84553
158 4ZRN NAD 2.84553
159 3HB5 NAP 2.84553
160 4ZRN UPG 2.84553
161 1KEW NAD 2.84553
162 3V1U NAD 2.84553
163 6F7L FAD 2.84553
164 1Z6Z NAP 2.84553
165 4J7U YTZ 2.84553
166 3SJ7 NDP 2.84553
167 4J7U NAP 2.84553
168 5UAO FAD 2.84553
169 1PJS NAD 2.84553
170 5OJ7 AR6 2.84553
171 2WPB ZZI 2.84553
172 1H9A NAP 2.84553
173 3WDM ADN 2.84553
174 3RJ5 NAD 2.84553
175 6FHO FAD 2.84553
176 4I5I NAD 2.84553
177 4BWL MN9 2.84553
178 1VKO NAD 2.84553
179 1H2B NAJ 2.84553
180 4XSU UDP 2.84553
181 4KXQ APR 2.84553
182 3EF0 ALF 2.84553
183 2AF6 BRU 2.84553
184 3DR4 G4M 2.84553
185 3ITJ FAD 2.84553
186 4FC7 NAP 2.88809
187 4FC7 COA 2.88809
188 5DF1 NAP 2.98913
189 5DF1 58X 2.98913
190 2XVM SAH 3.01508
191 3MQ2 SAH 3.21101
192 4XUC SAM 3.21101
193 4XUC 43G 3.21101
194 5CUQ NSC 3.25203
195 5JGL SAM 3.25203
196 4C4A SAH 3.25203
197 5JJR SAH 3.25203
198 3LKZ SFG 3.25203
199 3O7W SAM 3.25203
200 3A25 SAM 3.25203
201 4FN4 NAD 3.25203
202 5BJX NAD 3.25203
203 5BJX UDP 3.25203
204 5BVA FAD 3.25203
205 5Z75 NAD 3.25203
206 5TTJ FAD 3.25203
207 2GV8 FAD 3.25203
208 1VQW FAD 3.25203
209 1SB8 NAD 3.25203
210 1SB8 UD2 3.25203
211 2GVC FAD 3.25203
212 2WSB NAD 3.25203
213 2PX8 SAH 3.25203
214 1EFV FAD 3.25203
215 1EFV AMP 3.25203
216 5HXI 5HN 3.25203
217 2C7G FAD 3.25203
218 2C7G ODP 3.25203
219 5HXI FAD 3.25203
220 4K5S PM0 3.25203
221 4K5S FAD 3.25203
222 2Y6Q I7T 3.25203
223 2Y6Q FAD 3.25203
224 5BRT FAD 3.25203
225 5BRT CH9 3.25203
226 2XVF FAD 3.25203
227 2XVE FAD 3.25203
228 1COY FAD 3.25203
229 4YNU LGC 3.25203
230 4YNU FAD 3.25203
231 2R4J 13P 3.25203
232 2R4J FAD 3.25203
233 3NKS FAD 3.25203
234 4REP FAD 3.25203
235 2ZXI FAD 3.25203
236 1OC2 TDX 3.25203
237 1OC2 NAD 3.25203
238 3GMB FAD 3.25203
239 2CFC NAD 3.25203
240 1MO9 FAD 3.25203
241 1COY AND 3.25203
242 2AQJ FAD 3.25203
243 2AQJ TRP 3.25203
244 1MO9 KPC 3.25203
245 2GMH FAD 3.25203
246 4K26 NDP 3.25203
247 2WK1 SAH 3.25203
248 4K26 SFF 3.25203
249 1C3X 8IG 3.25203
250 1WVG APR 3.25203
251 1RLZ NAD 3.25203
252 4GKV NAD 3.25203
253 3UBM COA 3.25203
254 4X7Y SAH 3.25203
255 4LHD GLY 3.25203
256 4UP3 FAD 3.25203
257 3BJE URA 3.25203
258 2YYY NAP 3.25203
259 4QTU SAM 3.36538
260 1XCL SAH 3.40426
261 1M2K APR 3.61446
262 4KRI SAH 3.65854
263 6ECT SAM 3.65854
264 6ARJ SAH 3.65854
265 6ARJ BW4 3.65854
266 5DX0 SFG 3.65854
267 6C8R EQV 3.65854
268 6C8R SAH 3.65854
269 5DXA SFG 3.65854
270 5DX8 SFG 3.65854
271 5DWQ SFG 3.65854
272 5DX1 SFG 3.65854
273 6GFK SAH 3.65854
274 2AOT SAH 3.65854
275 1JQD SAH 3.65854
276 6D6Y SAH 3.65854
277 2HQM FAD 3.65854
278 4MO2 FDA 3.65854
279 1JQD HSM 3.65854
280 4MO2 FAD 3.65854
281 4DMG SAM 3.65854
282 5TS5 FAD 3.65854
283 2Q7V FAD 3.65854
284 4URF NAD 3.65854
285 3WMX NAD 3.65854
286 3IHG FAD 3.65854
287 1QO8 FAD 3.65854
288 3AYI FAD 3.65854
289 3AYI HCI 3.65854
290 3A4V NAD 3.65854
291 3A4V PYR 3.65854
292 5G3U FDA 3.65854
293 4RF2 NAP 3.65854
294 1YQZ FAD 3.65854
295 5XWV 8H6 3.65854
296 1NAA 6FA 3.65854
297 1NAA ABL 3.65854
298 1RYI FAD 3.65854
299 1RYI GOA 3.65854
300 2C5A NAD 3.65854
301 2C5A GDC 3.65854
302 5XWV NDP 3.65854
303 5G3U ITW 3.65854
304 4NTC FAD 3.65854
305 3RIY NAD 3.65854
306 3WGT FAD 3.65854
307 3WGT QSC 3.65854
308 1ZK4 NAP 3.65854
309 6EQS BV8 3.65854
310 1PS9 FAD 3.65854
311 4GLL NAD 3.65854
312 2PK3 A2R 3.65854
313 2ZAT NAP 3.65854
314 4JOB TLA 3.65854
315 1ZK4 AC0 3.65854
316 6HH6 A3R 3.65854
317 5M67 NAD 3.65854
318 5M67 3D1 3.65854
319 5M67 ADE 3.65854
320 1V8B NAD 3.65854
321 3WQQ IB3 3.65854
322 3WQQ NDP 3.65854
323 3OFK SAH 3.7037
324 3AY6 NAI 3.71747
325 3AY6 BGC 3.71747
326 1NVM NAD 3.76812
327 2BZG SAH 3.87931
328 5LW0 AR6 3.8961
329 1XDS SAM 4.01069
330 1P1C SAH 4.0201
331 3E3U NVC 4.06091
332 3FRH SAH 4.06504
333 5FUB SAH 4.06504
334 4PIO SAH 4.06504
335 4PIO AVI 4.06504
336 2EG5 SAH 4.06504
337 1G55 SAH 4.06504
338 5THY SAH 4.06504
339 1Y8Q ATP 4.06504
340 1UWK URO 4.06504
341 1UWK NAD 4.06504
342 5YJI SAH 4.06504
343 5YJI 8WO 4.06504
344 4AZW SAM 4.06504
345 4RPL FAD 4.06504
346 4RPL 3UC 4.06504
347 4HXY NDP 4.06504
348 5WGR FAD 4.06504
349 3HDY FDA 4.06504
350 3HDY GDU 4.06504
351 1E6W NAD 4.06504
352 5GWT NAD 4.06504
353 4HA6 FAD 4.06504
354 3HDY FAD 4.06504
355 5GWT SIN 4.06504
356 3FPZ AHZ 4.06504
357 2AE2 PTO 4.06504
358 3QJ4 FAD 4.06504
359 2AE2 NAP 4.06504
360 4Z24 FAD 4.06504
361 4YRY FAD 4.06504
362 5THZ SAH 4.06504
363 2WPF WPF 4.06504
364 2WPF FAD 4.06504
365 1BZL FAD 4.06504
366 1BZL GCG 4.06504
367 3NYC FAD 4.06504
368 3NYC IAR 4.06504
369 1S7G APR 4.06504
370 1W73 NAP 4.06504
371 3ZNN FAD 4.06504
372 3ZNN 4WL 4.06504
373 1W8D NAP 4.06504
374 3UCL FAD 4.06504
375 3UCL NAP 4.06504
376 3UCL CYH 4.06504
377 3T31 FAD 4.06504
378 3T31 DCQ 4.06504
379 6B3A SAM 4.06504
380 1S7G NAD 4.06504
381 1RM0 D6P 4.06504
382 1RM0 NAI 4.06504
383 5Y1G NAD 4.06504
384 5Y1G AKB 4.06504
385 2Q28 ADP 4.06504
386 1BC5 SAH 4.06504
387 1E3W NAD 4.06504
388 1H0H MGD 4.06504
389 2WYV NAD 4.06504
390 4YRY NAD 4.06504
391 1VDC FAD 4.06504
392 3H4V NAP 4.06504
393 3JQF NAP 4.06504
394 4CME NAP 4.06504
395 1V35 NAI 4.06504
396 3BMQ NAP 4.06504
397 3H4V DVP 4.06504
398 2VZ0 D64 4.06504
399 2VZ0 NAP 4.06504
400 5K6A NAP 4.06504
401 4CM9 NAP 4.06504
402 5Z2L NDP 4.08163
403 3WV8 ATP 4.12844
404 2XYQ SAH 4.13793
405 3PFG TLO 4.18251
406 3PFG SAM 4.18251
407 5JCA NDP 4.43038
408 5JCA FAD 4.43038
409 3H2B SAH 4.4335
410 1NM5 NAP 4.4335
411 1NM5 NAD 4.4335
412 3TKY SAH 4.47154
413 3DMH GMP 4.47154
414 5FWA J7C 4.47154
415 1FP2 SAH 4.47154
416 3DMH SAM 4.47154
417 5ULP KB1 4.47154
418 3ELW GP3 4.47154
419 3ELW SAM 4.47154
420 1FP2 HMO 4.47154
421 3GCZ SAM 4.47154
422 5ERG SAM 4.47154
423 1TPY SAH 4.47154
424 2ZWA SAH 4.47154
425 2OBF SAH 4.47154
426 2OBF F83 4.47154
427 5K0A FAD 4.47154
428 2RAB FAD 4.47154
429 2RAB NAD 4.47154
430 4YAC NAI 4.47154
431 2V6G NAP 4.47154
432 4D7E FAD 4.47154
433 2DKH 3HB 4.47154
434 2DKH FAD 4.47154
435 5MLR NAP 4.47154
436 5MLR GRQ 4.47154
437 3SSO SAH 4.47154
438 3CGD FAD 4.47154
439 1L1E SAH 4.47154
440 2YVF NAD 4.47154
441 2YVF FAD 4.47154
442 3CGD COA 4.47154
443 4D04 NAP 4.47154
444 4D04 FAD 4.47154
445 1GPE FAD 4.47154
446 3OZ2 FAD 4.47154
447 1BDB NAD 4.47154
448 4EMJ FAD 4.47154
449 3CGD NAD 4.47154
450 4EMI FAD 4.47154
451 4EMI NAD 4.47154
452 1BXK NAD 4.47154
453 4ZCC FAD 4.47154
454 4ZCC NAI 4.47154
455 1H5Q NAP 4.47154
456 1ZBQ NAD 4.47154
457 1VL8 NAP 4.47154
458 2RGJ FAD 4.47154
459 5T2U NAP 4.47154
460 3NTA FAD 4.47154
461 3FG2 FAD 4.47154
462 6DNT NAD 4.47154
463 3NTD FAD 4.47154
464 5THQ NDP 4.47154
465 3NT6 FAD 4.47154
466 4D79 ATP 4.47154
467 4RDH AMP 4.47154
468 3CTY FAD 4.47154
469 4RDI ATP 4.47154
470 5ODQ FAD 4.47154
471 1GEE NAD 4.47154
472 6DUB SAH 4.5045
473 6CZ7 MGD 4.70085
474 5ZZ6 NAD 4.80769
475 1DJL NAP 4.83092
476 3EGI ADP 4.85437
477 1I1N SAH 4.86726
478 1Z3C SA8 4.87805
479 3GWZ SAH 4.87805
480 6ECW SAH 4.87805
481 3GXO SAH 4.87805
482 1WG8 SAM 4.87805
483 6ECU SAH 4.87805
484 3FPF TNA 4.87805
485 3FPF MTA 4.87805
486 3EVF SAH 4.87805
487 3EVF GTA 4.87805
488 3P9C SAH 4.87805
489 3EVG SAH 4.87805
490 2P41 SAH 4.87805
491 4DCM SAM 4.87805
492 2WA2 SAM 4.87805
493 3A27 SAM 4.87805
494 4Y9D NAI 4.87805
495 4ONQ SFG 4.87805
496 2YY7 NAD 4.87805
497 1REO FAD 4.87805
498 3H8V ATP 4.87805
499 1YBH FAD 4.87805
500 5JAQ NAI 4.87805
501 4KGD TDP 4.87805
502 4KGD FAD 4.87805
503 3GF4 FAD 4.87805
504 2JJQ SAH 4.87805
505 3GF4 UPG 4.87805
506 3ICT FAD 4.87805
507 6FP4 E1T 4.87805
508 6FP4 FAD 4.87805
509 2AG5 NAD 4.87805
510 4DSG FAD 4.87805
511 4DSG UDP 4.87805
512 6BWL NAD 4.87805
513 3ICS FAD 4.87805
514 2F5Z FAD 4.87805
515 3ICR FAD 4.87805
516 3CGB FAD 4.87805
517 5GT9 NAP 4.87805
518 6H3O FAD 4.87805
519 5KMS FAD 4.87805
520 5EJ2 NAD 4.87805
521 2PZM UDP 4.87805
522 2PZM NAD 4.87805
523 4J1Q NDP 4.87805
524 3ZV6 NAD 4.87805
525 3ZV6 4HB 4.87805
526 5KMS NAD 4.87805
527 1OAA OAA 4.87805
528 1JNR FAD 4.87805
529 5EZ7 FAD 4.87805
530 5JE0 SAH 4.87805
531 5JE0 AZ8 4.87805
532 2EXX NAP 4.87805
533 3Q9T FAY 4.87805
534 5YEC ATP 4.87805
535 3CH6 NAP 4.8951
536 3CH6 311 4.8951
537 4NEC SAH 4.92424
538 3DUW SAH 4.93274
539 1PNO NAP 5
540 3LCC SAH 5.10638
541 2OOR TXP 5.17241
542 5NMX FAD 5.17647
543 5NMX NAP 5.17647
544 3IID APR 5.21327
545 3LU1 NAD 5.21978
546 3LST SAH 5.28455
547 5E8J SAH 5.28455
548 3BGD SAH 5.28455
549 3BGD PM6 5.28455
550 5E9W SAH 5.28455
551 4Y30 SAH 5.28455
552 4Y30 49L 5.28455
553 1SQF SAM 5.28455
554 4YUW 4JU 5.28455
555 4TQG NDP 5.28455
556 3C6K SPD 5.28455
557 1YY5 FAD 5.28455
558 4YUW S4M 5.28455
559 1RSG FAD 5.28455
560 3NUG NAD 5.28455
561 3C6K MTA 5.28455
562 3SQP FAD 5.28455
563 1LVL NAD 5.28455
564 3NDJ SAH 5.28455
565 3NDJ JHZ 5.28455
566 5U8U FAD 5.28455
567 6AIN FAD 5.28455
568 1LVL FAD 5.28455
569 6DEN TP9 5.28455
570 6DEN G8A 5.28455
571 6DEN FAD 5.28455
572 3LXD FAD 5.28455
573 4U8P UDP 5.28455
574 4U8P FDA 5.28455
575 3U31 NAD 5.28455
576 1RKX NAD 5.28455
577 3VZS CAA 5.28455
578 5J7X FAD 5.28455
579 3VZS NAP 5.28455
580 1R18 SAH 5.28634
581 1W6U NAP 5.29801
582 1D4O NAP 5.43478
583 1R37 NAD 5.4755
584 3FZG SAM 5.5
585 4G5H UD7 5.50964
586 4G5H NAP 5.50964
587 3FUU ADN 5.53506
588 3QOX SAH 5.69106
589 5MW4 5JU 5.69106
590 6C5B SAH 5.69106
591 5YF1 8V0 5.69106
592 5YF1 SFG 5.69106
593 2PWY SAH 5.69106
594 2YX1 SFG 5.69106
595 1RJD SAM 5.69106
596 2FK8 SAM 5.69106
597 5FTW SAH 5.69106
598 4BLW AMP 5.69106
599 1GET NAP 5.69106
600 1GET FAD 5.69106
601 4BLW SAH 5.69106
602 2VVM FAD 5.69106
603 3LZW NAP 5.69106
604 3LZW FAD 5.69106
605 2VVL FAD 5.69106
606 4J36 1HR 5.69106
607 4J36 FAD 5.69106
608 1T9D P25 5.69106
609 5WKC FAD 5.69106
610 1T9D PYD 5.69106
611 1T9D 1MM 5.69106
612 1NJR XYL 5.69106
613 5GSN FAD 5.69106
614 5GSN NAP 5.69106
615 5Y77 FAD 5.69106
616 5MZI FAD 5.69106
617 5MZI FYK 5.69106
618 5FJN BE2 5.69106
619 5FJN FAD 5.69106
620 1T9D FAD 5.69106
621 5GSN MMZ 5.69106
622 6ER9 NAP 5.69106
623 6ER9 FAD 5.69106
624 1AE1 NAP 5.69106
625 4ZA2 NAD 5.69106
626 1KNR FAD 5.69106
627 2Q6B HR2 5.69106
628 3ABI NAD 5.69106
629 2C31 TZD 5.69106
630 2C31 ADP 5.69106
631 6HOY AR6 5.69106
632 6HOY TSN 5.69106
633 3ZG6 APR 5.69106
634 2IZ1 ATR 5.69106
635 5OCM NAP 5.69106
636 5CG1 NAD BBN 5.69106
637 1QG6 NAD 5.69106
638 1QG6 TCL 5.69106
639 1VM6 NAD 5.70175
640 1LSS NAD 5.71429
641 5N5D SAM 5.75221
642 1JG3 ADN 5.95745
643 5LOG SAH 6.00858
644 1Q0S SAH 6.09756
645 3VSE SAH 6.09756
646 2O07 SPD 6.09756
647 6BQ6 TER 6.09756
648 2O07 MTA 6.09756
649 1I9G SAM 6.09756
650 5N0J FAD 6.09756
651 3KLJ FAD 6.09756
652 5W7R SAH 6.09756
653 3GD4 NAD 6.09756
654 3GD4 FAD 6.09756
655 5KOX RFP 6.09756
656 5KOX FAD 6.09756
657 5W7R 9Z7 6.09756
658 4BV6 FAD 6.09756
659 1R6D NAD 6.09756
660 3TKA SAM 6.09756
661 1E5Q NDP 6.09756
662 1R6D DAU 6.09756
663 5ZYN FAD 6.09756
664 1Z45 NAD 6.09756
665 2QQF A1R 6.09756
666 1SZD APR 6.09756
667 2OD9 A1R NCA 6.09756
668 3NJ4 NAD 6.09756
669 1CF2 NAP 6.09756
670 5K7U SAM 6.22222
671 5F2K OCA 6.25
672 5F2K SAH 6.25
673 5C2N NAG 6.25
674 3GU3 SAH 6.33803
675 2I5F 5IP 6.42202
676 3T7S SAM 6.50407
677 1QZZ SAM 6.50407
678 1U2Z SAH 6.50407
679 3MB5 SAM 6.50407
680 4M37 SAH 6.50407
681 3GRU AMP 6.50407
682 3GEG NAD 6.50407
683 6EL3 NAP 6.50407
684 2NVK FAD 6.50407
685 4M52 FAD 6.50407
686 4MOP 2H5 6.50407
687 3O03 NAP 6.50407
688 5KVA SAM 6.50407
689 4MIG G3F 6.50407
690 4M52 M52 6.50407
691 2A8X FAD 6.50407
692 2DT5 NAD 6.50407
693 5I7S NAD 6.50407
694 5I7S E9P 6.50407
695 1QH8 HCA 6.50407
696 1PR9 NAP 6.55738
697 3D3W NAP 6.55738
698 5IL1 SAM 6.60377
699 4YMH SAH 6.66667
700 4O0L NDP 6.90909
701 3TLJ SAH 6.91057
702 2EJU SAH 6.91057
703 4OBW SAM 6.91057
704 1N2X SAM 6.91057
705 4RSL FAD 6.91057
706 5ME4 HP4 6.91057
707 4X9M FAD 6.91057
708 2Q1W NAD 6.91057
709 2NYA MGD 6.91057
710 3I53 SAH 6.92771
711 4POO SAM 7
712 5JWC FAD 7.10173
713 5ZW3 SAH 7.11111
714 2Q1S NAI 7.1618
715 3Q87 SAM 7.2
716 1X87 NAD 7.25953
717 5DM1 SAH 7.31707
718 5DM1 5D7 7.31707
719 5X62 SAH 7.31707
720 1G60 SAM 7.31707
721 3S1S SAH 7.31707
722 2IID FAD 7.31707
723 2IID PHE 7.31707
724 3S5W FAD 7.31707
725 1O97 FAD 7.31707
726 1O97 AMP 7.31707
727 5HSA FAS 7.31707
728 1ELI PYC 7.31707
729 3RKR NAP 7.31707
730 2CVQ NDP 7.31707
731 1XVB BBU 7.31707
732 1XVB BHL 7.31707
733 1XA4 COA 7.31707
734 3VYW SAM 7.46753
735 5E1M PRO PRO LYS ARG ILE ALA 7.46888
736 5E1M SAH 7.46888
737 4YGM URA 7.69231
738 3ML1 MGD 7.72358
739 1O94 ADP 7.72358
740 1DJN ADP 7.72358
741 3ICC NAP 7.72358
742 5SWI BMA 7.72358
743 5OOH 9ZZ 7.76699
744 5OOH NAP 7.76699
745 1QAN SAH 7.78689
746 1E6E FAD 7.8125
747 2IVD FAD 7.94979
748 5MGZ SAH 8.05085
749 5YIZ EF2 8.10811
750 5YJ1 6EL 8.10811
751 5YJ0 EF2 8.10811
752 5MPT SAH 8.13008
753 1I8T FAD 8.13008
754 2GN4 NDP 8.13008
755 2GN4 UD1 8.13008
756 5MIT NAP 8.13008
757 5MIT FAD 8.13008
758 3EYA FAD 8.13008
759 1XKQ NDP 8.13008
760 5EB4 FAD 8.13008
761 1JA9 NDP 8.13008
762 2E5V FAD 8.13008
763 2WET FAD 8.13008
764 6CI9 NAP 8.13008
765 2DKN NAI 8.13008
766 4IJ6 SEP 8.13008
767 3G89 SAM 8.53659
768 5BSZ SAH 8.53659
769 1JQ3 AAT 8.53659
770 3K7M FAD 8.53659
771 4YAG NAI 8.53659
772 2B4Q NAP 8.53659
773 3AHC TPP 8.53659
774 3QFA FAD 8.62069
775 3PT9 SAH 8.94309
776 6FDF SAH 8.94309
777 1ZK7 FAD 8.94309
778 1H82 FAD 8.94309
779 1H82 GZZ 8.94309
780 4JNA FAD 8.94309
781 1Q9I FAD 8.94309
782 1Q9I TEO 8.94309
783 4L2I FAD 8.94309
784 4XQC NAD 8.94309
785 4XQC 13D 8.94309
786 2IV2 MGD 8.94309
787 1G8K MGD 8.94309
788 2QA1 FAD 9
789 1UAY ADN 9.09091
790 1TL2 NDG 9.32203
791 4R6W PC 9.34959
792 4R6W SAH 9.34959
793 2EFJ SAH 9.34959
794 6GKV SAH 9.34959
795 5F8F SFG 9.34959
796 4EUE NAI 9.34959
797 1V59 FAD 9.34959
798 1V59 NAD 9.34959
799 1Q1R FAD 9.34959
800 3AXB FAD 9.34959
801 3AXB PRO 9.34959
802 5TUF FAD 9.34959
803 5TUF TDC 9.34959
804 5I39 FAD 9.34959
805 1YC5 NCA 9.34959
806 4BUZ OCZ 9.34959
807 4BUZ OAD 9.34959
808 4BUZ NAD 9.34959
809 5A3B APR 9.34959
810 1YKJ PHB 9.34959
811 1YKJ FAD 9.34959
812 1RO7 CSF 9.34959
813 2CUL FAD 9.48276
814 1ZGA SAH 9.52381
815 2HNK SAH 9.62343
816 3X0D SAH 9.7561
817 2BRY FAD 9.7561
818 4TXI FAD 9.7561
819 4JDR FAD 9.7561
820 4AP3 FAD 9.7561
821 4AP3 NAP 9.7561
822 2UYQ SAM 9.7561
823 1EJ0 SAM 10
824 5L95 AMP 10
825 2YVJ FAD 10.0917
826 5E72 SAM 10.1626
827 3A4T SFG 10.1626
828 1I2B USQ 10.1626
829 1I2B NAD 10.1626
830 1I2B UPG 10.1626
831 2FR1 NDP 10.1626
832 2RGH FAD 10.1626
833 2PT9 2MH 10.2804
834 2PT9 S4M 10.2804
835 3GDH SAH 10.3734
836 1ORR NAD 10.3746
837 5M58 SAH 10.4348
838 4FZV SAM 10.5691
839 4E70 N7I 10.5691
840 2CDU FAD 10.5691
841 1D4D FAD 10.5691
842 3QVP FAD 10.5691
843 4WES HCA 10.5691
844 2CDU ADP 10.5691
845 2VT3 ATP 10.6977
846 3C3Y SAH 10.9705
847 1KPG SAH 10.9756
848 6B92 SAH 10.9756
849 5T67 JHZ 10.9756
850 5T67 SAH 10.9756
851 5XNC MTA 10.9756
852 4IV9 FAD 10.9756
853 2HMT NAI 11.1111
854 5WP5 SAH 11.3821
855 5VN0 FAD 11.3821
856 5VN0 NAI 11.3821
857 1U7T TDT 11.3821
858 1FL2 FAD 11.3821
859 4YKG FAD 11.3821
860 4YKG NAD 11.3821
861 1FK8 NAD 11.3821
862 1U7T NAD 11.3821
863 3OJO NAD 11.3821
864 4ZVV GN0 11.3821
865 4ZVV NAD 11.3821
866 5UR0 NAD 11.3821
867 2I7C AAT 11.6608
868 1NNU TCT 11.6667
869 1NNU NAD 11.6667
870 2BOS GLA GAL GLC NBU 11.7647
871 2BOS GLA GAL GLC 11.7647
872 1F3L SAH 11.7886
873 1GTE FAD 11.7886
874 4D5G FAD 11.7886
875 4D5G TPP 11.7886
876 1LVK MNT BEF 11.7886
877 3JWH SAH 11.9816
878 2ZFU SAH 12.093
879 4KWI NAP 12.1673
880 4KWI 1TJ 12.1673
881 1KPH SAH 12.1951
882 5GWX SAM 12.1951
883 5GWX SAR 12.1951
884 2BGM NAJ 12.1951
885 2NPX FAD 12.1951
886 2NPX NAD 12.1951
887 3X0V FAD 12.1951
888 3CBG SAH 12.1951
889 1KQF MGD 12.1951
890 1RPN NDP 12.2388
891 4J56 FAD 12.2807
892 5YJF SAH 12.6016
893 5YJF 8WO 12.6016
894 2Z3Y F2N 12.6016
895 4AT0 FAD 12.6016
896 5EOW FAD 12.6016
897 5TUK FAD 12.6016
898 5GM1 SAH 12.7946
899 3BXO SAM 12.9707
900 1UDB NAD 13.0081
901 1UDB UFG 13.0081
902 2RGO FAD 13.4146
903 5ICE 2H4 13.8211
904 5ICE SAH 13.8211
905 4HSU FAD 13.8211
906 4FWE FAD 13.8211
907 4GUS FAD 13.8211
908 4GUT FAD 13.8211
909 2B9W FAD 13.8211
910 4C3Y FAD 14.2276
911 3M6W SAM 14.2276
912 4C3Y ANB 14.2276
913 2YBQ UP2 14.2276
914 4CQM NAP 14.6341
915 4II2 ATP 14.7239
916 2BD0 NAP 14.7541
917 5EEH SAH 14.8936
918 5EEH P9P 14.8936
919 1KUJ MMA 15.0376
920 4RVG TYD 15.0407
921 4RVG SAM 15.0407
922 1UXG NAD 15.0407
923 1UXG FUM 15.0407
924 5KOK SAH 15.4472
925 5WP4 SAH 15.4472
926 5KOK S9T 15.4472
927 5KOK R9T 15.4472
928 4USR FAD 15.4472
929 5BUK FAD 15.8537
930 4YSX FAD 15.9574
931 2GAG NAD 16.1616
932 2GAG FAD 16.1616
933 2GAG FOA 16.1616
934 5BW4 SAM 16.2602
935 1NV8 SAM 16.6667
936 1NV8 MEQ 16.6667
937 5DNK SAH 16.6667
938 4LWP SAH 17.0732
939 6F5Z SAH 17.4797
940 5W7M SAH 17.4797
941 3G5S FAD 17.4797
942 4GQB 0XU 18.1818
943 3AD8 NAD 18.1818
944 3AD8 PYC 18.1818
945 3AD8 FAD 18.1818
946 4NBW NAD 18.2879
947 1U1I NAD 18.6992
948 4M38 SAH 19.0476
949 1DL5 SAH 19.1057
950 3OU2 SAH 19.2661
951 1WY7 SAH 19.8068
952 4KIB SAH 19.9187
953 3VC1 SAH 19.9187
954 3VC1 GST 19.9187
955 5FA5 MTA 20
956 4M73 M72 20.3252
957 4M73 SAH 20.3252
958 3KIF GDL 20.7547
959 4PNE SAH 21.5447
960 5FA8 SAM 21.7391
961 4USQ FAD 22.7642
962 1VE3 SAM 22.9075
963 6GAR FAD 23.5772
964 5W7K SAH 23.9837
965 5EIN NAP 24.0741
966 3HVJ 705 24.8869
967 1L3I SAH 25
968 2PXX SAH 26.0465
969 5U19 827 28.8618
970 5U19 SAH 28.8618
971 3RNM FAD 29.3103
972 5DLY SAH 29.6748
973 5DLY 5D7 29.6748
974 5HJM MTA 33.7398
Pocket No.: 2; Query (leader) PDB : 2VDV; Ligand: SAM; Similar sites found with APoc: 10
This union binding pocket(no: 2) in the query (biounit: 2vdv.bio3) has 18 residues
No: Leader PDB Ligand Sequence Similarity
1 1P31 EPU 2.43902
2 1KEW TYD 2.84553
3 3RUV ANP 4.87805
4 1H74 ADP 5.28455
5 4PLG NAI 5.28455
6 4PLG OXM 5.28455
7 1OMO NAD 6.09756
8 5LTJ BEF 8.13008
9 2YVJ NAI 10.0917
10 6GMN F4E 14.1975
Pocket No.: 3; Query (leader) PDB : 2VDV; Ligand: SAM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2vdv.bio1) has 18 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 4; Query (leader) PDB : 2VDV; Ligand: SAM; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2vdv.bio2) has 18 residues
No: Leader PDB Ligand Sequence Similarity
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