-->
Receptor
PDB id Resolution Class Description Source Keywords
2W5T 1.6 Å EC: 7.-.-.- STRUCTURE-BASED MECHANISM OF LIPOTEICHOIC ACID SYNTHESIS BY STAPHYLOCOCCUS AUREUS LTAS. STAPHYLOCOCCUS AUREUS TRANSMEMBRANE GLYCEROL-PHOSPHATE CELL WALL BIOGENESIS/DEGRADATION LTAS MEMBRANE SECRETED TRANSFERASE CELL MEMBRANE
Ref.: STRUCTURE-BASED MECHANISM OF LIPOTEICHOIC ACID SYNTHESIS BY STAPHYLOCOCCUS AUREUS LTAS. PROC.NATL.ACAD.SCI.USA V. 106 1584 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ACT A:1643;
Invalid;
none;
submit data
59.044 C2 H3 O2 CC(=O...
GP9 A:1644;
Valid;
none;
submit data
170.058 C3 H7 O6 P C(C(C...
MN A:1642;
Part of Protein;
none;
submit data
54.938 Mn [Mn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2W5T 1.6 Å EC: 7.-.-.- STRUCTURE-BASED MECHANISM OF LIPOTEICHOIC ACID SYNTHESIS BY STAPHYLOCOCCUS AUREUS LTAS. STAPHYLOCOCCUS AUREUS TRANSMEMBRANE GLYCEROL-PHOSPHATE CELL WALL BIOGENESIS/DEGRADATION LTAS MEMBRANE SECRETED TRANSFERASE CELL MEMBRANE
Ref.: STRUCTURE-BASED MECHANISM OF LIPOTEICHOIC ACID SYNTHESIS BY STAPHYLOCOCCUS AUREUS LTAS. PROC.NATL.ACAD.SCI.USA V. 106 1584 2009
Members (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 293 families.
1 2W5T - GP9 C3 H7 O6 P C(C(COP(=O....
2 2W5R - GP9 C3 H7 O6 P C(C(COP(=O....
3 2W5S - GP9 C3 H7 O6 P C(C(COP(=O....
70% Homology Family (3)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 250 families.
1 2W5T - GP9 C3 H7 O6 P C(C(COP(=O....
2 2W5R - GP9 C3 H7 O6 P C(C(COP(=O....
3 2W5S - GP9 C3 H7 O6 P C(C(COP(=O....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 204 families.
1 2W5T - GP9 C3 H7 O6 P C(C(COP(=O....
2 2W5R - GP9 C3 H7 O6 P C(C(COP(=O....
3 2W5S - GP9 C3 H7 O6 P C(C(COP(=O....
4 4UOR - GP9 C3 H7 O6 P C(C(COP(=O....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GP9; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 GP9 1 1
2 1GP 0.551724 0.90625
3 G3P 0.551724 0.90625
4 GPE 0.421053 0.707317
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2W5T; Ligand: GP9; Similar sites found with APoc: 34
This union binding pocket(no: 1) in the query (biounit: 2w5t.bio1) has 15 residues
No: Leader PDB Ligand Sequence Similarity
1 1C7O PPG 1.50376
2 3EI9 PL6 1.65094
3 2ZW5 COA 2.32558
4 4LH7 NMN 2.47678
5 2CBZ ATP 2.53165
6 3T01 PPF 2.59434
7 4P6X HCY 2.7451
8 5YSQ INS 2.7972
9 3B8X G4M 2.82051
10 1YNH SUO 3.06604
11 6BND OPE 3.19767
12 5WBF LAC 3.33333
13 1EGD FAD 3.53535
14 4E1Z 0MX 3.78007
15 5VEO AMP 3.84615
16 5EGH PC 4.24528
17 6AYH C3G 4.47761
18 5NM7 GLY 4.88722
19 1XPJ TLA 6.34921
20 4Y9J UCC 6.83962
21 1EI6 PPF 6.89655
22 2PS1 PRP 8.40708
23 6F30 UD1 8.49057
24 5LIA 6XN 8.72641
25 1M32 PLP 8.74317
26 3ITJ CIT 8.87574
27 1RYI FAD 9.42408
28 1RYI GOA 9.42408
29 2GSU AMP 9.92366
30 3IT6 ORN 10.2439
31 5B5S BOG 11.1111
32 4KM2 TOP 11.1732
33 4KM2 ATR 11.1732
34 1E2S CSN 15.3302
APoc FAQ
Feedback