Receptor
PDB id Resolution Class Description Source Keywords
2WA2 1.8 Å NON-ENZYME: STRUCTURAL STRUCTURE OF THE METHYLTRANSFERASE DOMAIN FROM MODOC VIRUS, A FLAVIVIRUS WITH NO KNOWN VECTOR (NKV) MODOC VIRUS TRANSFERASE S-ADENOSYL-L- METHIONINE VIRION MEMBRANE FLAVIVIRUS MODOC VIRUS N7-METHYLTRANSFERASE 2-prime -O-METHYLTRANSFERASE TRANSMEMBRANE ENVELOPE PROTEIN METHYLTRANSFERASE
Ref.: STRUCTURE OF THE METHYLTRANSFERASE DOMAIN FROM THE MODOC VIRUS, A FLAVIVIRUS WITH NO KNOWN VECTOR. ACTA CRYSTALLOGR.,SECT.D V. 65 796 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SAM A:1248;
B:1267;
Valid;
Valid;
none;
none;
submit data
398.437 C15 H22 N6 O5 S C[S@@...
SO4 A:1249;
B:1268;
B:1269;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
96.063 O4 S [O-]S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2WA2 1.8 Å NON-ENZYME: STRUCTURAL STRUCTURE OF THE METHYLTRANSFERASE DOMAIN FROM MODOC VIRUS, A FLAVIVIRUS WITH NO KNOWN VECTOR (NKV) MODOC VIRUS TRANSFERASE S-ADENOSYL-L- METHIONINE VIRION MEMBRANE FLAVIVIRUS MODOC VIRUS N7-METHYLTRANSFERASE 2-prime -O-METHYLTRANSFERASE TRANSMEMBRANE ENVELOPE PROTEIN METHYLTRANSFERASE
Ref.: STRUCTURE OF THE METHYLTRANSFERASE DOMAIN FROM THE MODOC VIRUS, A FLAVIVIRUS WITH NO KNOWN VECTOR. ACTA CRYSTALLOGR.,SECT.D V. 65 796 2009
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 5 families.
1 2WA2 - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 2WA2 - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (45)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3EVA - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 3EVC - SAH C14 H20 N6 O5 S c1nc(c2c(n....
3 3EVF - SAH C14 H20 N6 O5 S c1nc(c2c(n....
4 3EVB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
5 3EVD - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 3EVE - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 3ELU - SAM C15 H22 N6 O5 S C[S@@+](CC....
8 3ELW - SAM C15 H22 N6 O5 S C[S@@+](CC....
9 3EMD - SFG C15 H23 N7 O5 c1nc(c2c(n....
10 3ELD - SFG C15 H23 N7 O5 c1nc(c2c(n....
11 3ELY - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 3EMB - SAM C15 H22 N6 O5 S C[S@@+](CC....
13 2P3L - G3A C20 H27 N10 O17 P3 c1nc(c2c(n....
14 2P41 - G1G C22 H32 N10 O18 P3 Cn1c[n+](c....
15 1L9K - SAH C14 H20 N6 O5 S c1nc(c2c(n....
16 5M5B - SAM C15 H22 N6 O5 S C[S@@+](CC....
17 5GOZ - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
18 5GP1 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
19 5KQR - SAM C15 H22 N6 O5 S C[S@@+](CC....
20 5ULP Kd = 24.3 uM KB1 C21 H26 F N7 O5 c1cc(ccc1C....
21 5MRK - SFG C15 H23 N7 O5 c1nc(c2c(n....
22 5WXB - SAH C14 H20 N6 O5 S c1nc(c2c(n....
23 5KQS - SAM C15 H22 N6 O5 S C[S@@+](CC....
24 3LKZ - SFG C15 H23 N7 O5 c1nc(c2c(n....
25 3EVG - SAH C14 H20 N6 O5 S c1nc(c2c(n....
26 2PX5 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
27 2PXA - SAH C14 H20 N6 O5 S c1nc(c2c(n....
28 2PX8 - MGT C11 H20 N5 O14 P3 CN1CN(C2=C....
29 2PX2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
30 2PX4 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
31 5E9Q - SAM C15 H22 N6 O5 S C[S@@+](CC....
32 5EHG - 5O0 C20 H16 Cl N3 O6 S c1cc(cc(c1....
33 5EKX - 2CQ C7 H9 Cl N2 Cc1cc(c(cc....
34 4R8S - SFG C15 H23 N7 O5 c1nc(c2c(n....
35 4CTJ - 3A9 C9 H8 O3 c1cc2c(cc1....
36 4CTK - SAM C15 H22 N6 O5 S C[S@@+](CC....
37 5EC8 - 5LP C15 H14 Cl N3 O3 Cc1ccc(c(c....
38 5EIW - X0V C7 H7 F3 N2 c1cc(c(cc1....
39 3P8Z - SAH C14 H20 N6 O5 S c1nc(c2c(n....
40 5CUQ ic50 = 7.7 uM NSC C21 H20 N6 O Cc1cc(c2cc....
41 5EIF - 4M0 C8 H9 N O2 Cc1ccc(c(c....
42 5EHI - 5O3 C20 H17 Cl N4 O5 S c1cc(cc(c1....
43 3P97 - SAM C15 H22 N6 O5 S C[S@@+](CC....
44 3GCZ - SAM C15 H22 N6 O5 S C[S@@+](CC....
45 2WA2 - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAM; Similar ligands found: 192
No: Ligand ECFP6 Tc MDL keys Tc
1 SAM 1 1
2 SMM 0.792683 0.96
3 S4M 0.6875 0.909091
4 S7M 0.670455 0.945946
5 M2T 0.636364 0.878378
6 GEK 0.612903 0.931507
7 SAI 0.571429 0.878378
8 XYA 0.565789 0.773333
9 ADN 0.565789 0.773333
10 RAB 0.565789 0.773333
11 5CD 0.564103 0.783784
12 EP4 0.5625 0.826667
13 SA8 0.56044 0.945205
14 SFG 0.555556 0.875
15 5X8 0.555556 0.888889
16 5N5 0.551282 0.773333
17 A4D 0.544304 0.797297
18 EEM 0.542553 0.945946
19 SAH 0.537634 0.916667
20 DTA 0.536585 0.789474
21 62X 0.535354 0.884615
22 MTA 0.53012 0.875
23 3DH 0.517647 0.849315
24 AMP MG 0.511364 0.710843
25 5AL 0.510417 0.743902
26 VMS 0.510204 0.673913
27 54H 0.510204 0.673913
28 0UM 0.51 0.857143
29 A 0.505747 0.707317
30 AMP 0.505747 0.707317
31 ABM 0.505618 0.753086
32 A5A 0.505155 0.688889
33 DAL AMP 0.50505 0.765432
34 NVA LMS 0.504951 0.725275
35 K15 0.5 0.883117
36 6RE 0.5 0.78481
37 5AD 0.5 0.75
38 SSA 0.5 0.684783
39 SON 0.5 0.746988
40 SRP 0.5 0.746988
41 LSS 0.49505 0.706522
42 CA0 0.494624 0.714286
43 A12 0.494505 0.705882
44 AP2 0.494505 0.705882
45 ME8 0.490385 0.841463
46 5CA 0.49 0.684783
47 TSB 0.49 0.681319
48 53H 0.49 0.666667
49 ACP 0.489362 0.694118
50 5AS 0.48913 0.648936
51 ADP 0.48913 0.690476
52 A2D 0.488889 0.690476
53 J7C 0.488889 0.772152
54 ZAS 0.488636 0.769231
55 8QN 0.485149 0.743902
56 GAP 0.484536 0.73494
57 AN2 0.483871 0.682353
58 A3S 0.483871 0.813333
59 A7D 0.483871 0.851351
60 GJV 0.483516 0.775
61 SRA 0.483146 0.694118
62 LAD 0.480769 0.752941
63 KAA 0.480769 0.698925
64 GSU 0.480769 0.722222
65 AMO 0.480392 0.746988
66 DSZ 0.480392 0.703297
67 52H 0.48 0.666667
68 ADP MG 0.478723 0.702381
69 M33 0.478723 0.722892
70 MAO 0.478261 0.82716
71 BA3 0.478261 0.690476
72 AOC 0.477778 0.776316
73 DSH 0.477778 0.842105
74 NEC 0.477778 0.75
75 SXZ 0.47619 0.894737
76 AHX 0.475728 0.701149
77 Y3J 0.47561 0.706667
78 G5A 0.474227 0.684783
79 A3T 0.473684 0.8
80 ADP BEF 0.473684 0.686047
81 BEF ADP 0.473684 0.686047
82 B4P 0.473118 0.690476
83 AP5 0.473118 0.690476
84 A3N 0.472527 0.766234
85 KB1 0.471698 0.833333
86 LEU LMS 0.471154 0.706522
87 APC 0.46875 0.705882
88 PRX 0.46875 0.73494
89 PAJ 0.466019 0.712644
90 4AD 0.466019 0.759036
91 RBY 0.463918 0.72619
92 ADP PO3 0.463918 0.728395
93 ADV 0.463918 0.72619
94 ADX 0.463158 0.666667
95 MHZ 0.463158 0.82716
96 AU1 0.463158 0.674419
97 YAP 0.462963 0.738095
98 TXA 0.462264 0.72619
99 NB8 0.462264 0.72093
100 A3G 0.461538 0.802632
101 VRT 0.459184 0.842105
102 ATP MG 0.459184 0.702381
103 YSA 0.458716 0.684783
104 XAH 0.458716 0.715909
105 50T 0.458333 0.682353
106 ATP 0.458333 0.690476
107 7D7 0.45679 0.723684
108 ANP MG 0.455446 0.678161
109 KH3 0.455357 0.871795
110 ACQ 0.454545 0.694118
111 AQP 0.453608 0.690476
112 5FA 0.453608 0.690476
113 AR6 0.453608 0.710843
114 APR 0.453608 0.710843
115 NSS 0.451923 0.703297
116 FA5 0.449541 0.746988
117 AGS 0.44898 0.678161
118 SAP 0.44898 0.678161
119 A5D 0.44898 0.789474
120 AD9 0.44898 0.674419
121 PTJ 0.448598 0.72093
122 YLB 0.448276 0.758621
123 YLP 0.447368 0.738636
124 D3Y 0.446602 0.792208
125 ADP ALF 0.445545 0.678161
126 ALF ADP 0.445545 0.678161
127 TYR AMP 0.445455 0.746988
128 MYR AMP 0.444444 0.776471
129 3AM 0.444444 0.674699
130 OAD 0.443396 0.73494
131 2VA 0.443299 0.779221
132 OOB 0.442308 0.722892
133 S8M 0.442308 0.831169
134 ADP VO4 0.441176 0.702381
135 VO4 ADP 0.441176 0.702381
136 ANP 0.44 0.674419
137 TAT 0.44 0.686047
138 WAQ 0.439252 0.75
139 ARG AMP 0.438596 0.727273
140 YLC 0.435897 0.755814
141 AAT 0.435644 0.797468
142 3OD 0.435185 0.73494
143 1ZZ 0.435185 0.755814
144 NVA 2AD 0.434343 0.815789
145 DLL 0.433962 0.722892
146 00A 0.433962 0.689655
147 7MD 0.433628 0.715909
148 ATF 0.431373 0.666667
149 SO8 0.43 0.792208
150 3UK 0.429907 0.714286
151 A6D 0.429907 0.72619
152 5SV 0.428571 0.741176
153 AMP DBH 0.428571 0.714286
154 WSA 0.42735 0.692308
155 TYM 0.42735 0.746988
156 9SN 0.427273 0.681818
157 AHZ 0.426087 0.755814
158 A A 0.425926 0.710843
159 3NZ 0.425926 0.807692
160 P5A 0.425926 0.691489
161 PR8 0.425926 0.744186
162 A1R 0.424528 0.709302
163 2A5 0.424242 0.674419
164 7MC 0.423729 0.719101
165 7D5 0.422222 0.658824
166 FYA 0.422018 0.722892
167 JB6 0.422018 0.709302
168 AYB 0.421488 0.75
169 PLP AAD 0.419355 0.764045
170 A22 0.419048 0.682353
171 MAP 0.419048 0.659091
172 2AM 0.417582 0.666667
173 TAD 0.417391 0.712644
174 A3P 0.416667 0.686747
175 ADP BMA 0.416667 0.714286
176 25A 0.415094 0.690476
177 YLA 0.413223 0.719101
178 ADQ 0.411215 0.694118
179 48N 0.410256 0.72093
180 0XU 0.41 0.824324
181 NAD IBO 0.406504 0.717647
182 7D3 0.40625 0.643678
183 PAP 0.405941 0.678571
184 OVE 0.404255 0.662791
185 4UV 0.403509 0.697674
186 ALF ADP 3PG 0.403361 0.712644
187 AF3 ADP 3PG 0.403361 0.712644
188 LA8 ALF 3PG 0.403361 0.712644
189 3AD 0.402299 0.783784
190 CMP 0.402062 0.691358
191 2BA 0.402062 0.682927
192 7C5 0.4 0.731707
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2WA2; Ligand: SAM; Similar sites found: 225
This union binding pocket(no: 1) in the query (biounit: 2wa2.bio2) has 20 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3LCV SAM 0.00142 0.44172 1.08696
2 4U00 ADP 0.009024 0.43365 1.63934
3 3ZF8 GDP 0.01468 0.40192 1.63934
4 2YX1 SFG 0.000002799 0.56416 1.81159
5 4ONQ SFG 0.00003598 0.49139 1.81159
6 4DMG SAM 0.0002291 0.48258 1.81159
7 5DNK SAH 0.0006576 0.46667 1.81159
8 2XT3 ADP 0.0208 0.40933 1.81159
9 1Q0S SAH 0.000002769 0.49211 1.9305
10 1JJV ATP 0.008253 0.42552 1.94175
11 3G2O SAM 0.00001212 0.51099 2.17391
12 5KVA SAM 0.00002448 0.47637 2.17391
13 5F8F SFG 0.0003011 0.46623 2.17391
14 2DPM SAM 0.00006127 0.45838 2.17391
15 1GOJ ADP 0.01306 0.42239 2.17391
16 1QAN SAH 0.000002152 0.51326 2.45902
17 3GDH SAH 0.00000003926 0.55023 2.48963
18 4N49 SAM 0.00000000526 0.62424 2.53623
19 3GU3 SAH 0.000003915 0.57325 2.53623
20 1WG8 SAM 0.000004845 0.5547 2.53623
21 4KRG SAH 0.0000165 0.51621 2.53623
22 4KIB SAH 0.00006437 0.49045 2.53623
23 3VYW SAM 0.00001823 0.48529 2.53623
24 2AWN ADP 0.005349 0.44893 2.53623
25 4A6D SAM 0.0004524 0.43795 2.53623
26 3O26 NDP 0.01022 0.41161 2.53623
27 3LRE ADP 0.02177 0.40794 2.53623
28 1G0N PHH 0.02158 0.40784 2.53623
29 1G0N NDP 0.02609 0.40112 2.53623
30 3A4T SFG 0.000006181 0.49628 2.55474
31 3FUU ADN 0.003836 0.40195 2.58303
32 2NXE SAM 0.001074 0.43045 2.75591
33 3G89 SAM 0.0003052 0.47121 2.81124
34 1C3V PDC 0.01406 0.41226 2.85714
35 2JHP SAH 0.0001444 0.47516 2.89855
36 5JGL SAM 0.0003621 0.45776 2.89855
37 5XVQ SAH 0.00006423 0.45056 2.89855
38 1RJD SAM 0.0003486 0.43597 2.89855
39 3I53 SAH 0.0006912 0.42459 2.89855
40 2VVG ADP 0.02045 0.40958 2.89855
41 1NV8 MEQ 0.0003473 0.40277 2.89855
42 4IEE AGS 0.01808 0.40159 2.89855
43 3EGI ADP 0.004863 0.43485 2.91262
44 3T7S SAM 0.00005952 0.49447 2.98507
45 1P1C SAH 0.0002905 0.42794 3.01508
46 2PZE ATP 0.01066 0.42832 3.05677
47 1R18 SAH 0.000004383 0.50109 3.0837
48 5N5D SAM 0.0009125 0.44457 3.09735
49 3FRH SAH 0.000844 0.45187 3.16206
50 5JE0 AZ8 0.000002265 0.44805 3.23887
51 5JE0 SAH 0.000002265 0.44805 3.23887
52 1G55 SAH 0.000002859 0.52743 3.26087
53 3TLJ SAH 0.0000005702 0.5217 3.26087
54 5HJM MTA 0.00000736 0.50923 3.26087
55 2ZIF SAM 0.000007775 0.5083 3.26087
56 3TKA SAM 0.00002366 0.48195 3.26087
57 3M6W SAM 0.0001506 0.47965 3.26087
58 3GWZ SAH 0.0003163 0.4705 3.26087
59 4KRI SAH 0.00007678 0.46034 3.26087
60 5X62 SAH 0.0003896 0.45637 3.26087
61 3GXO SAH 0.0009589 0.4438 3.26087
62 1V59 NAD 0.005232 0.41905 3.26087
63 2WHX ADP 0.01261 0.41762 3.26087
64 1TZD ADP 0.01809 0.41482 3.27273
65 5LOG SAH 0.00007113 0.4729 3.43348
66 2BZG SAH 0.0006025 0.43998 3.44828
67 3BGD SAH 0.0004303 0.41842 3.46154
68 5FTW SAH 0.0003858 0.43525 3.51562
69 4LJ9 ACP 0.01368 0.40341 3.53982
70 3P2E SAH 0.001362 0.41492 3.55556
71 2JBH 5GP 0.01081 0.41265 3.55556
72 5E9W SAH 0.0000102 0.54571 3.62319
73 1SQF SAM 0.000004596 0.52911 3.62319
74 1I9G SAM 0.000003906 0.51444 3.62319
75 5THY SAH 0.000004389 0.51316 3.62319
76 1FP1 SAH 0.0001088 0.48593 3.62319
77 1U2Z SAH 0.000149 0.48566 3.62319
78 1MO9 KPC 0.0121 0.44294 3.62319
79 1MO9 FAD 0.01277 0.44122 3.62319
80 2AOT SAH 0.002008 0.42948 3.62319
81 4BLW SAH 0.0003773 0.41058 3.62319
82 1Z3C SA8 0.0001264 0.40701 3.62319
83 3BXO SAM 0.00004693 0.5083 3.76569
84 1G6H ADP 0.01154 0.42657 3.89105
85 2W58 ADP 0.01331 0.42126 3.9604
86 3LST SAH 0.0002702 0.47363 3.98551
87 1ZGA SAH 0.0004702 0.46265 3.98551
88 1I1N SAH 0.000007531 0.45636 3.98551
89 3QOX SAH 0.0001007 0.44204 3.98551
90 5XVK SAH 0.0002358 0.42992 3.98551
91 4EIP FAD 0.02538 0.40698 3.98551
92 4USR FAD 0.01695 0.4049 3.98551
93 4POO SAM 0.00005833 0.44832 4
94 3A27 SAM 0.0001946 0.46156 4.04412
95 5BTX CMP 0.01198 0.40818 4.10959
96 2A14 SAH 0.0008587 0.41624 4.18251
97 5MGZ SAH 0.000268 0.44743 4.23729
98 5GVR LMR 0.001077 0.4885 4.2735
99 3CBG SAH 0.0004272 0.45463 4.31034
100 4GQB 0XU 0.000009533 0.47052 4.34783
101 1F3L SAH 0.00007647 0.45359 4.34783
102 5FA5 MTA 0.0007203 0.44934 4.34783
103 5M58 SAH 0.000253 0.44833 4.34783
104 5MW4 5JU 0.00003133 0.40816 4.34783
105 1UAY ADN 0.002786 0.42738 4.54545
106 5E1M SAH 0.00001906 0.48589 4.56432
107 3DXY SAM 0.000828 0.4565 4.58716
108 3JWH SAH 0.0000162 0.53634 4.60829
109 3C3Y SAH 0.00001798 0.49708 4.64135
110 4AZT SAM 0.0006098 0.44058 4.71014
111 2Q1S NAI 0.009678 0.42646 4.71014
112 4AZW SAM 0.001321 0.41924 4.71014
113 2HMT NAI 0.0008598 0.41395 4.86111
114 2VDV SAM 0.00002608 0.51995 4.87805
115 1LSS NAD 0.0004619 0.43053 5
116 3A4M ADP 0.01525 0.40969 5
117 3LN9 FLC 0.004125 0.4026 5.03597
118 2JJQ SAH 0.000002986 0.56288 5.07246
119 2EG5 SAH 0.00003958 0.51168 5.07246
120 1N2X SAM 0.000001858 0.50631 5.07246
121 2XYQ SAH 0.00004952 0.4875 5.07246
122 5THZ SAH 0.0000126 0.48424 5.07246
123 2PT9 S4M 0.000147 0.42172 5.07246
124 2ZFU SAH 0.00006311 0.46305 5.11628
125 1XTP SAI 0.00006514 0.48051 5.11811
126 1VE3 SAM 0.0001258 0.46925 5.28634
127 3DUW SAH 0.0006296 0.43413 5.38117
128 4UCI SAM 0.00000009035 0.58689 5.43478
129 5IL1 SAM 0.0001478 0.46572 5.43478
130 1BZL FAD 0.0115 0.44977 5.43478
131 3MB5 SAM 0.0000007451 0.5228 5.4902
132 5K7U SAM 0.0001711 0.46315 5.73066
133 3O7W SAM 0.0001194 0.4898 5.7971
134 2EFJ SAH 0.00007898 0.48658 5.7971
135 5GM1 SAH 0.00008329 0.44669 5.7971
136 3ICR FAD 0.022 0.40371 5.7971
137 5XLX SAH 0.005055 0.40218 5.7971
138 2XVM SAH 0.000009767 0.5394 6.03015
139 3PT9 SAH 0.000005814 0.52515 6.15942
140 4LWP SAH 0.00007455 0.49018 6.15942
141 3TKY SAH 0.0001135 0.48452 6.15942
142 5K6A NAP 0.006996 0.41923 6.15942
143 3COB ADP 0.01893 0.41059 6.15942
144 4OBW SAM 0.0002282 0.4579 6.22568
145 4BQS ADP 0.01378 0.41192 6.25
146 2HNK SAH 0.0001111 0.45776 6.27615
147 4NEC SAH 0.000007148 0.53864 6.43939
148 3OFK SAH 0.005922 0.40482 6.48148
149 1XTT U5P 0.008238 0.4021 6.48148
150 5KOK SAH 0.000003047 0.52602 6.52174
151 4C4A SAH 0.00001667 0.49615 6.52174
152 3DMH SAM 0.0001437 0.45054 6.52174
153 4N9Z V3L 0.009428 0.44011 6.52174
154 5KOK R9T 0.00001497 0.41597 6.52174
155 5KOK S9T 0.00001661 0.40982 6.52174
156 3DMH GMP 0.0002316 0.40594 6.52174
157 2PWY SAH 0.000001774 0.50731 6.58915
158 1EJ0 SAM 0.0000004519 0.57185 6.66667
159 3EGV SAH 0.001287 0.43374 6.80272
160 1JG3 ADN 0.001128 0.42913 6.80851
161 1YXM ADE 0.00008089 0.52305 6.88406
162 5MPT SAH 0.00001079 0.51474 6.88406
163 5E72 SAM 0.000008025 0.49066 6.88406
164 2EJU SAH 0.0001384 0.46748 6.88406
165 4PNE SAH 0.00004671 0.45603 6.88406
166 2ZWA SAH 0.0006164 0.42114 6.88406
167 1L1E SAH 0.000963 0.42028 6.88406
168 2FK8 SAM 0.001606 0.41208 6.88406
169 3H2B SAH 0.00009901 0.4645 6.89655
170 1IM8 SAI 0.00002518 0.47978 6.96721
171 2UYQ SAM 0.00005203 0.54133 7.09677
172 1O5I NAD 0.004075 0.40076 7.22892
173 4M37 SAH 0.0000433 0.48014 7.24638
174 4M38 SAH 0.00004059 0.47253 7.24638
175 4J1Q NDP 0.001351 0.44926 7.24638
176 1UZN NAP 0.003017 0.42159 7.28745
177 2AE2 NAP 0.001856 0.45798 7.30769
178 3MQ2 SAH 0.0009554 0.43939 7.33945
179 2CBZ ATP 0.01583 0.4174 7.59494
180 2D2F ADP 0.01754 0.41275 7.6
181 4FZV SAM 0.0000006791 0.53991 7.6087
182 5CDH TLA 0.01709 0.41339 7.97101
183 1XDS SAM 0.0004555 0.46328 8.02139
184 5FA8 SAM 0.00004313 0.45608 8.07453
185 1JJ7 ADP 0.01105 0.42772 8.07692
186 3Q87 SAM 0.0001593 0.43518 8.23529
187 3S1S SAH 0.00001958 0.46947 8.33333
188 4YMH SAH 0.000162 0.4515 8.33333
189 5BW4 SAM 0.001077 0.43713 8.33333
190 1GXU 2HP 0.008994 0.40385 8.79121
191 1KPH SAH 0.001312 0.40904 9.05797
192 1KPG SAH 0.001449 0.40899 9.05797
193 1TPY SAH 0.001017 0.41305 9.42029
194 1WY7 SAH 0.0000007757 0.52609 9.66184
195 1ZQ9 SAM 0.002569 0.41442 9.78261
196 3RKR NAP 0.00055 0.47039 9.92366
197 1RZ1 NAD 0.02283 0.40318 9.93789
198 3A25 SAM 0.001781 0.42107 10.6312
199 1G60 SAM 0.00000171 0.53664 10.7692
200 1NW5 SAM 0.00001141 0.50359 10.8696
201 1QZZ SAM 0.0002449 0.47557 10.8696
202 1KYZ SAH 0.0004604 0.44548 10.8696
203 1W5T ADP 0.004708 0.40917 10.8696
204 2PS1 ORO 0.009298 0.41589 11.5044
205 4QTU SAM 0.00000326 0.52452 11.8519
206 3VSE SAH 0.00006627 0.50775 11.9565
207 4DCM SAM 0.000205 0.47367 12.6812
208 5DX1 SFG 0.00001246 0.45778 12.6812
209 5DX8 SFG 0.00005849 0.44978 12.6812
210 5DXA SFG 0.00006569 0.44769 12.6812
211 5DWQ SFG 0.00008386 0.43739 12.6812
212 5DX0 SFG 0.00008954 0.43009 12.6812
213 3VC1 SAH 0.00002784 0.46433 13.0435
214 5TVI O8N 0.002256 0.45859 13.0435
215 1L3I SAH 0.000003775 0.47213 14.0625
216 3OU2 SAH 0.00001877 0.45742 14.6789
217 5E8J SAH 0.000009388 0.54019 15.9091
218 4Y2H SAH 0.0002922 0.49512 16.3043
219 4Y2H 49K 0.0004123 0.488 16.3043
220 5L95 AMP 0.003181 0.40449 18.75
221 3X0D SAH 0.0001804 0.45584 19.5652
222 2PXX SAH 0.000005986 0.51429 21.3953
223 4IWN GEK 0.00001594 0.52921 22.2707
224 1DL5 SAH 0.000002849 0.47414 24.6377
225 3LCC SAH 0.00005468 0.49354 26.8085
Pocket No.: 2; Query (leader) PDB : 2WA2; Ligand: SAM; Similar sites found: 10
This union binding pocket(no: 2) in the query (biounit: 2wa2.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4WOH 4NP 0.019 0.40049 None
2 3L8H FX1 0.02253 0.40072 2.23464
3 4IF4 BEF 0.00791 0.42989 2.88462
4 1R6D NAD 0.02755 0.41745 2.89855
5 1R6D DAU 0.03065 0.41435 2.89855
6 4EIP K2C 0.03157 0.41001 3.98551
7 2GJP MAL 0.02923 0.40178 5.43478
8 5CGE 51F 0.01299 0.40464 6.15942
9 2HK9 ATR 0.01047 0.40488 6.18182
10 2GUE NAG 0.003044 0.42536 8.19672
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