Receptor
PDB id Resolution Class Description Source Keywords
2WMG 2.3 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLY HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE TIGR4 (SP4GH98) IN W ITH THE LEWISY PENTASACCHARIDE BLOOD GROUP ANTIGEN. STREPTOCOCCUS PNEUMONIAE HYDROLASE GLYCOSIDE HYDROLASE STREPTOCOCCUS PNEUMONIAE LEBLOOD GROUP ANTIGEN FUCOSE UTILIZATION
Ref.: DIFFERENTIAL RECOGNITION AND HYDROLYSIS OF HOST CARBOHYDRATE-ANTIGENS BY STREPTOCOCCUS PNEUMONIAE F GLYCOSIDE HYDROLASES. J.BIOL.CHEM. V. 284 26161 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG FUC GAL FUC B:1;
 Valid;
 none;
 submit data
n/a n/a
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2WMH 1.7 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF THE CATALYTIC MODULE OF A FAMILY 98 GLY HYDROLASE FROM STREPTOCOCCUS PNEUMONIAE TIGR4 IN COMPLEX WID ISACCHARIDE BLOOD GROUP ANTIGEN. STREPTOCOCCUS PNEUMONIAE HYDROLASE GLYCOSIDE HYDROLASE STREPTOCOCCUS PNEUMONIAE BLANTIGEN FUCOSE UTILIZATION
Ref.: DIFFERENTIAL RECOGNITION AND HYDROLYSIS OF HOST CARBOHYDRATE-ANTIGENS BY STREPTOCOCCUS PNEUMONIAE F GLYCOSIDE HYDROLASES. J.BIOL.CHEM. V. 284 26161 2009
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 552 families.
1 2WMH - GAL FUC n/a n/a
2 2WMG - NAG FUC GAL FUC n/a n/a
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 426 families.
1 2WMH - GAL FUC n/a n/a
2 2WMG - NAG FUC GAL FUC n/a n/a
50% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 2WMH - GAL FUC n/a n/a
2 2WMG - NAG FUC GAL FUC n/a n/a
3 4D71 - NAG GAL FUC A2G n/a n/a
4 2WMK - NAG FUC GAL FUC A2G n/a n/a
5 4D72 - NAG GAL FUC A2G n/a n/a
6 2WMJ - GAL FUC GLA n/a n/a
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: NAG FUC GAL FUC; Similar ligands found: 0
No: Ligand ECFP6 Tc MDL keys Tc
Similar Ligands (3D)
Ligand no: 1; Ligand: NAG FUC GAL FUC; Similar ligands found: 6
No: Ligand Similarity coefficient
1 NAG FUC GAL FUC 1.0000
2 MAG FUC GAL FUC 0.9702
3 NDG FUC GAL FUC 0.9659
4 NDG GAL FUC FUC 0.9593
5 NAG GAL FUC FUC 0.9560
6 MAG GAL FUC FUC 0.8963
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2WMH; Ligand: GAL FUC; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2wmh.bio1) has 20 residues
No: Leader PDB Ligand Sequence Similarity
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