Receptor
PDB id Resolution Class Description Source Keywords
2X77 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF LEISHMANIA MAJOR ADP RIBOSYLATION FACTOR-LIKE 1. LEISHMANIA MAJOR GTP-BINDING PROTEIN SMALL GTPASE NUCLEOTIDE-BINDING
Ref.: CRYSTAL STRUCTURE OF LEISHMANIA MAJOR ADP RIBOSYLATION FACTOR-LIKE 1 AND A CLASSIFICATION OF RELATED GTPASE FAMILY MEMBERS IN THIS KINETOPLASTID. MOL.BIOCHEM.PARASITOL. V. 174 141 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GDP A:188;
B:188;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:189;
B:189;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2X77 2.1 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF LEISHMANIA MAJOR ADP RIBOSYLATION FACTOR-LIKE 1. LEISHMANIA MAJOR GTP-BINDING PROTEIN SMALL GTPASE NUCLEOTIDE-BINDING
Ref.: CRYSTAL STRUCTURE OF LEISHMANIA MAJOR ADP RIBOSYLATION FACTOR-LIKE 1 AND A CLASSIFICATION OF RELATED GTPASE FAMILY MEMBERS IN THIS KINETOPLASTID. MOL.BIOCHEM.PARASITOL. V. 174 141 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (9)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 1RRG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 1HUR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1O3Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
5 3N5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 3AQ4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
7 4Y0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 4YLG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 1MR3 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
50% Homology Family (19)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 181 families.
1 4V0K - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
2 4V0L - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
3 2X77 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 1RRG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
5 1HUR - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
6 1O3Y - GTP C10 H16 N5 O14 P3 c1nc2c(n1[....
7 1FZQ Kd = 24 nM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
8 1Z6Y - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
9 1ZJ6 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
10 1YZG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
11 3N5C - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
12 1E0S - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
13 1ZD9 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
14 2AL7 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
15 3AQ4 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
16 4Y0V - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
17 4YLG - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
18 1MR3 - G3D C10 H16 N5 O14 P3 c1nc2c(n1[....
19 4BAS - GNP C10 H17 N6 O13 P3 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2X77; Ligand: GDP; Similar sites found: 472
This union binding pocket(no: 1) in the query (biounit: 2x77.bio1) has 17 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1CLU DBG 0.000000002197 0.77269 None
2 3KUD GDP 0.0000000005335 0.75348 None
3 1UJ2 ADP 0.00007755 0.51997 None
4 1UJ2 C5P 0.0001195 0.51087 None
5 1GXU 2HP 0.0003609 0.499 None
6 2F3R G5P 0.002734 0.4522 None
7 4KVX ACO 0.02263 0.4003 None
8 4TTQ ATP 0.00003449 0.50288 1.0582
9 4QM7 GTP 0.00002063 0.51119 1.16959
10 1SKQ GDP 0.000000003306 0.66714 1.5873
11 1LVG ADP 0.0000004694 0.55352 1.5873
12 2ZFI ADP 0.00001021 0.54413 1.5873
13 1ION ADP 0.000173 0.48308 1.5873
14 2GWH A3P 0.009985 0.40589 1.5873
15 1AQU A3P 0.01278 0.40085 1.5873
16 1F2U ATP 0.0006538 0.47511 2.02703
17 1NVU GTP 0.0000000004687 0.77281 2.1164
18 1NVV GNP 0.000000000608 0.76733 2.1164
19 3BOS CDP 0.00007968 0.4859 2.1164
20 2Z5F A3P 0.005104 0.42345 2.1164
21 1CJW COT 0.024 0.40169 2.40964
22 2RCN GDP 0.00000000004821 0.7609 2.6455
23 2JLR ANP 0.0000741 0.50284 2.6455
24 1B0U ATP 0.0001051 0.4958 2.6455
25 3B7G ANP 0.000572 0.45647 2.6455
26 4R2I ANP 0.0002256 0.45235 2.6455
27 4PX9 ADP 0.0004764 0.44366 2.6455
28 4PJ3 ANP 0.005734 0.41511 2.6455
29 2I4I AMP 0.007495 0.41173 2.6455
30 3TK1 GDP 0.0000000002417 0.69055 3.1746
31 5KUT GDP 0.000000008658 0.67716 3.1746
32 3E70 GDP 0.0000005592 0.59428 3.1746
33 5L3W GDP 0.000002317 0.56945 3.1746
34 5I0H ADP BEF 0.00006255 0.51387 3.1746
35 3FYH ADP 0.0001452 0.50294 3.1746
36 3QXC ATP 0.0001818 0.50204 3.1746
37 1KK8 BEF ADP 0.0001415 0.49236 3.1746
38 1D2N ANP 0.0002416 0.48612 3.1746
39 1YQT ADP 0.00001257 0.48404 3.1746
40 1DAK DPU 0.001086 0.48312 3.1746
41 2GDJ ANP 0.0001563 0.47466 3.1746
42 1G6O ADP 0.0002666 0.46024 3.1746
43 1XX6 ADP 0.0006098 0.44589 3.1746
44 4QRH 0O2 0.007441 0.41569 3.1746
45 4KBF AMP 0.002513 0.41436 3.1746
46 3CV2 OXL 0.02153 0.40059 3.1746
47 4RD0 GDP 0.00000000216 0.72822 3.7037
48 2QN6 GDP 0.0000000003302 0.70779 3.7037
49 5KSP GDP 0.00000005823 0.63926 3.7037
50 5KSZ GCP 0.0000001266 0.62768 3.7037
51 1H65 GDP 0.000005382 0.5668 3.7037
52 3A4M ADP 0.000001524 0.53476 3.7037
53 3ZQ6 ADP ALF 0.00005111 0.52875 3.7037
54 2VVG ADP 0.0000003872 0.50692 3.7037
55 1XKV ATP 0.00009081 0.49599 3.7037
56 2QZ4 ADP 0.00009503 0.49508 3.7037
57 1RRC ADP 0.000002772 0.49066 3.7037
58 1QF9 C5P 0.0006531 0.48837 3.7037
59 1QF9 ALF 0.0006531 0.48837 3.7037
60 1QF9 ADP 0.0006531 0.48837 3.7037
61 4FCW ADP 0.0004748 0.46018 3.7037
62 1U0J ADP 0.000209 0.4588 3.7037
63 2ZE7 DST 0.002066 0.45088 3.7037
64 3DKP ADP 0.0005279 0.45046 3.7037
65 2B8T THM 0.001587 0.44942 3.7037
66 2ZE7 AMP 0.002192 0.44801 3.7037
67 2C9O ADP 0.0001399 0.43654 3.7037
68 5EP2 AZU 0.003477 0.43135 3.7037
69 3BER AMP 0.0051 0.41737 3.7037
70 1D8T GDP 0.0000000003152 0.72538 4.2328
71 2HCJ GDP 0.000000000168 0.71927 4.2328
72 2BVN GNP 0.000000001695 0.66913 4.2328
73 1G3Q ADP 0.00008871 0.49354 4.2328
74 1IN4 ADP 0.0001622 0.492 4.2328
75 3DC4 ADP 0.00001981 0.48998 4.2328
76 1W5T ANP 0.002061 0.4421 4.2328
77 3VM7 GLC 0.003977 0.44024 4.2328
78 4A4Z ANP 0.001099 0.4366 4.2328
79 5WRI A3P 0.003923 0.43071 4.2328
80 1NST A3P 0.003487 0.4273 4.2328
81 4E5N NAD 0.01228 0.41986 4.2328
82 1W5T ADP 0.006414 0.41491 4.2328
83 1G3M PCQ 0.02976 0.40692 4.2328
84 1G3M A3P 0.02976 0.40692 4.2328
85 1Q20 PLO 0.02614 0.40461 4.2328
86 1Q20 A3P 0.02614 0.40461 4.2328
87 2C5L GTP 0.0000000005397 0.76984 4.2735
88 5WRJ A3P 0.003531 0.43638 4.62046
89 1SVI GDP 0.00000000004554 0.74248 4.7619
90 2C77 GNP 0.00000001092 0.69151 4.7619
91 5L3V GDP 0.0000005792 0.59722 4.7619
92 1JI0 ATP 0.000001893 0.59716 4.7619
93 5L3S GNP 0.000002098 0.59128 4.7619
94 2C78 GNP 0.000000004448 0.59098 4.7619
95 3ZFD ANP 0.00003365 0.51587 4.7619
96 1XP8 AGS 0.00001139 0.51357 4.7619
97 2C04 GCP 0.000007426 0.50938 4.7619
98 1V8K ANP 0.00003151 0.50464 4.7619
99 4PFO ADP 0.0001798 0.50042 4.7619
100 1UKZ ADP 0.0003982 0.49503 4.7619
101 1FP6 ADP 0.0001194 0.49321 4.7619
102 3QKT ANP 0.0003567 0.4842 4.7619
103 1T5C ADP 0.000002676 0.47883 4.7619
104 4HSE ADP 0.0001941 0.47796 4.7619
105 2IS6 ADP 0.0003647 0.457 4.7619
106 5LB3 ADP 0.0003067 0.45485 4.7619
107 4HUT ATP 0.01039 0.42094 4.7619
108 2ZEJ GDP 0.00000005656 0.67196 4.8913
109 5GLN XYS 0.01593 0.40484 4.94186
110 3NHB ADP 0.000003924 0.59027 5.29101
111 2NCD ADP 0.00000721 0.57471 5.29101
112 3UIE ANP 0.000009777 0.54062 5.29101
113 4KFU ACP 0.000001663 0.52072 5.29101
114 1QF5 GDP 0.0002847 0.52028 5.29101
115 4P32 ADP 0.000059 0.51738 5.29101
116 3FB4 AP5 0.0003175 0.5079 5.29101
117 4MKF AP5 0.0005622 0.49653 5.29101
118 4X8O AP5 0.0006956 0.49621 5.29101
119 2AWN ADP 0.0000002032 0.48935 5.29101
120 1QF5 RPL 0.0445 0.43078 5.29101
121 1QHH ATP 0.007542 0.40512 5.29101
122 4Q1A 2XZ 0.0004773 0.55385 5.71429
123 4Q1A UDP 0.0004773 0.55385 5.71429
124 3KTA AP5 0.0002074 0.45473 5.78035
125 4NCN GTP 0.000000001056 0.74637 5.82011
126 2QEN ADP 0.000002566 0.57372 5.82011
127 5H56 ADP 0.00003059 0.5452 5.82011
128 5H56 TYD 0.00003059 0.5452 5.82011
129 1ZIN AP5 0.0001958 0.51852 5.82011
130 5GJC ATP 0.00003316 0.50278 5.82011
131 2DPY ADP 0.0002932 0.48866 5.82011
132 1G41 ADP 0.0002287 0.47749 5.82011
133 1R6B ADP 0.0002107 0.47633 5.82011
134 1OS1 ATP 0.0007951 0.47424 5.82011
135 1OS1 PYR 0.0008549 0.47424 5.82011
136 1JJV ATP 0.00008358 0.46019 5.82011
137 5TIV A3P 0.005257 0.44923 5.82011
138 3FVQ ATP 0.000324 0.42005 5.82011
139 1VKJ A3P 0.008684 0.4125 5.82011
140 3IUY AMP 0.005164 0.40741 5.82011
141 1J99 AND 0.02569 0.40499 5.82011
142 3IIJ ADP 0.000007918 0.52998 6.11111
143 3DDC GNP 0.0000000006203 0.76691 6.13497
144 4LC1 GDP 0.000000002041 0.71784 6.34921
145 1KK1 GNP 0.000000005429 0.65875 6.34921
146 1WQ1 GDP 0.000000001263 0.59024 6.34921
147 5I34 GDP 0.00001786 0.52541 6.34921
148 1SQ5 ADP 0.00004671 0.50629 6.34921
149 2IXE ATP 0.0001063 0.50523 6.34921
150 4IEE AGS 0.0002052 0.48942 6.34921
151 4GOX A3P 0.0003648 0.48179 6.34921
152 2W58 ADP 0.000003333 0.47274 6.34921
153 4TMK T5A 0.001988 0.46037 6.34921
154 4LJ9 ACP 0.002001 0.4259 6.34921
155 2D7D ADP 0.003391 0.41467 6.34921
156 5MEX SZZ 0.03809 0.40047 6.34921
157 1B7T ADP 0.000483 0.46251 6.41026
158 3Q72 GNP 0.0000000001309 0.72318 6.62651
159 4YMU ATP 0.00001891 0.5011 6.66667
160 2RGX AP5 0.0006866 0.49326 6.79612
161 4MKG AP5 0.0001189 0.52947 6.87831
162 2QG6 NMN 0.00009569 0.5174 6.87831
163 5X40 ACP 0.00007907 0.51352 6.87831
164 1S3G AP5 0.0002573 0.51252 6.87831
165 4ZNL BEF ADP 0.00006033 0.5012 6.87831
166 4WZ6 ATP 0.00001637 0.48082 6.87831
167 2XAU ADP 0.0002831 0.47321 6.87831
168 1F5N GNP 0.00009211 0.40658 6.87831
169 1VHT BA3 0.000797 0.45248 6.88073
170 4U5X GNP 0.000000002475 0.71838 7.30337
171 1G7S GDP 0.0000000005727 0.73116 7.40741
172 2XTN GTP 0.000002162 0.58819 7.40741
173 1M7G ADX 0.000008306 0.57484 7.40741
174 1M7G ADP 0.000008459 0.57066 7.40741
175 3W5J GDP 0.00000005824 0.55942 7.40741
176 3DEF GDP 0.000004496 0.55934 7.40741
177 1M7G AV2 0.0000008535 0.55913 7.40741
178 3TMK T5A 0.00001953 0.5529 7.40741
179 4WZA ACP 0.0002382 0.53264 7.40741
180 4WZA ADP 0.0002382 0.53264 7.40741
181 4D81 ADP 0.0001077 0.4953 7.40741
182 4IDN GNP 0.0001788 0.4945 7.40741
183 3DZD ADP 0.0003825 0.46975 7.40741
184 1T8U UAP SGN IDS SGN 0.00917 0.43395 7.40741
185 1T8U A3P 0.004601 0.42559 7.40741
186 5MZN ADP 0.003973 0.40213 7.40741
187 4OI4 ATP 0.0001208 0.50472 7.82609
188 2WOJ ADP ALF 0.00004265 0.53255 7.93651
189 4XTR ATP 0.00003754 0.52897 7.93651
190 4XVU ATP 0.00004562 0.52493 7.93651
191 1OXV ANP 0.000008692 0.51507 7.93651
192 1BG2 ADP 0.0000004453 0.50476 7.93651
193 5TSH ANP 0.00003154 0.50384 7.93651
194 4XTR ADP 0.0001159 0.49886 7.93651
195 2ZPA ADP 0.0001348 0.49577 7.93651
196 2CHG ANP 0.0002949 0.47745 7.93651
197 2WHX ADP 0.00002713 0.47132 7.93651
198 5TSH ADP 0.00003302 0.46957 7.93651
199 3ZS9 ADP ALF 0.00005414 0.42176 7.93651
200 3TBK ANP 0.00166 0.4143 7.93651
201 4BQS K2Q 0.00001415 0.5702 7.95455
202 4BQS ADP 0.00001854 0.53198 7.95455
203 1LFD GNP 0.0000000008011 0.75851 8.04598
204 1GOJ ADP 0.0000003365 0.65363 8.46561
205 4P4T GDP 0.000000171 0.55799 8.46561
206 4CVN ADP 0.00001377 0.55446 8.46561
207 1W0J ADP 0.000008813 0.54577 8.46561
208 2ZR9 DTP 0.000003489 0.54539 8.46561
209 3VX3 ADP 0.00007639 0.50737 8.46561
210 4R43 GDP 0.0001557 0.48857 8.46561
211 5BQ5 ADP BEF 0.0001182 0.47719 8.46561
212 2FAH GDP 0.000383 0.46972 8.46561
213 4IHQ ADP 0.0001116 0.46916 8.46561
214 1W0J ADP BEF 0.00107 0.45349 8.46561
215 1G7C 5GP 0.0000001266 0.61285 8.51064
216 1BO4 COA 0.002019 0.4363 8.92857
217 1DAR GDP 0.000000003961 0.67848 8.99471
218 1TQ4 GDP 0.00000000195 0.61383 8.99471
219 1XMV ADP 0.00002094 0.52224 8.99471
220 1CR1 TTP 0.00009156 0.50604 8.99471
221 5N69 ADP 0.0001408 0.48989 8.99471
222 2FSH ANP 0.001915 0.42202 8.99471
223 2IYL GDP 0.000001427 0.58426 9.15493
224 1MKY GDP 0.0000000001294 0.74211 9.52381
225 4WOP CTP 0.0006531 0.4657 9.52381
226 2GMV UN8 0.002391 0.44937 9.52381
227 1NHX FTB 0.008778 0.43877 9.52381
228 1NHX PEP 0.008713 0.43801 9.52381
229 2GMV PEP 0.004757 0.43764 9.52381
230 2BEK ATP 0.0002376 0.42325 9.52381
231 4HDO GNP 0.0000000007594 0.76265 10.0529
232 5FG3 GDP 0.00000000003481 0.74709 10.0529
233 1KAO GDP 0.0000000007083 0.74 10.0529
234 3PQC GDP 0.00000000113 0.69455 10.0529
235 1NF3 GNP 0.00000002515 0.68631 10.0529
236 4LPS GDP 0.0000001323 0.62294 10.0529
237 1GUA GNP 0.0000000009753 0.55801 10.0529
238 1IHU AF3 0.00005037 0.52064 10.0529
239 1IHU ADP 0.00005609 0.52064 10.0529
240 3COB ADP 0.000001443 0.50437 10.0529
241 1F9V ADP 0.000005511 0.50007 10.0529
242 1OFH ADP 0.000409 0.46584 10.0529
243 1Z6T ADP 0.0001058 0.45649 10.0529
244 2PL3 ADP 0.0005268 0.44319 10.1695
245 1JJ7 ADP 0.000000424 0.65928 10.582
246 3FWY ADP 0.00003078 0.52331 10.582
247 1NJF AGS 0.00009637 0.50725 10.582
248 1NJF ADP 0.00008838 0.5044 10.582
249 3P4X ADP 0.00002042 0.50209 10.582
250 4U00 ADP 0.0000006416 0.49306 10.582
251 3B5J 12D 0.00002422 0.4857 10.582
252 1ZUI SKM 0.0001052 0.52669 10.7143
253 3BFV ADP 0.00002227 0.51161 11.0701
254 1JWY GDP 0.0000006174 0.59937 11.1111
255 3H86 AP5 0.00008303 0.53034 11.1111
256 1JWY ADP 0.0001852 0.4789 11.1111
257 4AG5 ADP 0.000005188 0.58362 11.6402
258 1P9B GDP 0.00002811 0.52515 11.6402
259 4ZG4 VO4 ADP 0.00006087 0.51895 11.6402
260 2Q2Y ADP 0.0003601 0.50514 11.6402
261 2Y65 ADP 0.000001663 0.50377 11.6402
262 2Q2Y MKR 0.0003794 0.50276 11.6402
263 2VHJ ADP 0.004301 0.42697 11.6402
264 1D2E GDP 0.000000006421 0.69143 12.1693
265 1IWE IMP 0.0001907 0.55962 12.1693
266 3BD9 A3P 0.00877 0.40211 12.1693
267 1KO8 6PG 0.00007334 0.5082 12.5714
268 1YRB GDP 0.0000000001013 0.77508 12.6984
269 2VB6 ADP BEF 0.00008546 0.51191 12.6984
270 2B8W ALF 5GP 0.0001743 0.49913 12.6984
271 3H4S ADP 0.000002583 0.49542 12.6984
272 4FRZ ADP 0.00001018 0.4894 12.6984
273 2VF7 ADP 0.0002577 0.47233 12.6984
274 4IOK ADP 0.001084 0.4661 12.6984
275 4IOK XPO 0.0008496 0.4661 12.6984
276 2J0V GDP 0.0000000007838 0.72492 13.2275
277 1WF3 GNP 0.000000004579 0.72485 13.2275
278 1I4D GDP 0.0000000003739 0.70217 13.2275
279 4B47 GDP 0.00000000001944 0.75768 13.7566
280 1RYH GNP 0.00000000166 0.71447 13.7566
281 1DS6 GDP 0.000000000818 0.70605 13.7566
282 2FJU GSP 0.000000005906 0.70412 13.7566
283 3SBD GNP 0.00000001228 0.70133 13.7566
284 2W2X GSP 0.00000001264 0.6885 13.7566
285 1G4U GDP 0.00000001432 0.59613 13.7566
286 1HE1 GDP 0.00000001094 0.58523 13.7566
287 2KIN ADP 0.0000004577 0.50404 13.7566
288 1HE1 AF3 0.01976 0.4013 13.7566
289 1MH1 GNP 0.000000006758 0.71666 14.2857
290 1NN5 ANP 0.00002962 0.54765 14.2857
291 3KJI ADP 0.00004904 0.51116 14.2857
292 1G6H ADP 0.0000004547 0.49843 14.2857
293 3RC3 ANP 0.0007108 0.43884 14.2857
294 3R7F CP 0.01906 0.40113 14.2857
295 1E96 GTP 0.00000001294 0.70024 14.8148
296 2WKQ GTP 0.000000009359 0.56271 14.8148
297 2XT3 ADP 0.000001364 0.50484 14.8148
298 2CE7 ADP 0.0001395 0.48739 14.8148
299 1FNN ADP 0.0001224 0.44542 14.8148
300 4YS0 ADP 0.001586 0.4433 14.8148
301 4HI0 GDP 0.0000001567 0.54825 15.3439
302 1OE0 TTP 0.01064 0.4163 15.3439
303 3Q85 GNP 0.0000000001007 0.74638 15.3846
304 1PUJ GNP 0.000000005361 0.69507 15.873
305 4DID GDP 0.000000007693 0.67951 15.873
306 3B9Q MLI 0.000002842 0.60585 15.873
307 3RLF ANP 0.0002926 0.48637 15.873
308 5L3R GCP 0.000002876 0.47628 15.873
309 2OG2 MLI 0.0000007697 0.43351 15.873
310 1OYY AGS 0.001579 0.43072 15.873
311 1YTM ATP 0.0002788 0.43054 15.873
312 2PEZ DAT 0.00002445 0.55348 16.2011
313 2PEZ GGZ 0.00002445 0.55348 16.2011
314 1X1R GDP 0.0000000006125 0.76717 16.2921
315 2V7Q ATP 0.000006438 0.54899 16.4384
316 2V7Q ADP 0.0009419 0.44031 16.4384
317 2CK3 ANP 0.001132 0.4126 16.4384
318 5UQW GDP 0.0000000002067 0.78361 16.9312
319 4DSU GDP 0.0000000004059 0.77583 16.9312
320 1A4R GDP 0.000000004239 0.7074 16.9312
321 1A4R GNH 0.000000005438 0.69864 16.9312
322 5TB5 GDP 0.0000000001626 0.76101 17.2973
323 5TAR GDP 0.0000000001657 0.70745 17.2973
324 3WXM GTP 0.000000006552 0.71449 17.4603
325 4ITR GDP 0.00000001229 0.68567 17.4603
326 2NGR GDP 0.000000006224 0.68372 17.4603
327 1GRN GDP 0.00000001829 0.67404 17.4603
328 2OFW ADX 0.00003399 0.55559 17.4603
329 2UZI GTP 0.0000000004864 0.76896 17.5439
330 3EC1 GDP 0.00000000106 0.71893 17.9894
331 2XTZ GSP 0.00000001155 0.70262 17.9894
332 3T1O GDP 0.0000001034 0.63173 17.9894
333 3T12 GDP ALF 0.0000001055 0.54659 17.9894
334 1P72 ADP 0.00008213 0.52746 17.9894
335 4D0N GDP 0.000000001092 0.70164 18.5185
336 1CXZ GSP 0.0000000248 0.67784 18.5185
337 1W7J ADP BEF 0.0001275 0.45312 18.5185
338 5XCO GDP 0.00000000008227 0.77928 18.7134
339 5O2T GSP 0.0000000005161 0.77078 18.9349
340 2GJ8 ALF GDP 0.0000000007214 0.56313 19.0476
341 3ZIA ADP 0.0000189 0.53038 19.0476
342 3ZIA ATP 0.00001723 0.52612 19.0476
343 1NY5 ADP 0.0007168 0.45943 19.0476
344 5UFQ GNP 0.000000000423 0.77188 19.2771
345 5UWP GNP 0.0000000002245 0.79132 19.5767
346 4HAT GNP 0.0000000002284 0.79096 19.5767
347 5DIF GNP 0.000000000203 0.79041 19.5767
348 5UWW GNP 0.000000000218 0.78891 19.5767
349 5UWI GNP 0.0000000002194 0.78877 19.5767
350 5UWU GNP 0.0000000002284 0.78793 19.5767
351 5UWO GNP 0.0000000002453 0.78643 19.5767
352 5DHF GNP 0.0000000002555 0.78557 19.5767
353 5UWS GNP 0.0000000003226 0.78366 19.5767
354 5DI9 GNP 0.0000000003508 0.78189 19.5767
355 5UWT GNP 0.0000000003062 0.78176 19.5767
356 5UWH GNP 0.0000000003072 0.7817 19.5767
357 3GJ0 GDP 0.00000000009113 0.78124 19.5767
358 3M1I GTP 0.0000000003524 0.7788 19.5767
359 3GJ8 GDP 0.0000000002076 0.75134 19.5767
360 3GJ5 GDP 0.0000000002202 0.75017 19.5767
361 3GJ3 GDP 0.00000000008428 0.74937 19.5767
362 5BXQ GDP 0.0000000002298 0.74932 19.5767
363 3GJ4 GDP 0.00000000009468 0.74755 19.5767
364 3GJ7 GDP 0.0000000001187 0.74326 19.5767
365 3CH5 GDP 0.0000000003575 0.74053 19.5767
366 1IBR GNP 0.0000000002416 0.57322 19.5767
367 5UWJ GNP 0.0000000002525 0.57289 19.5767
368 2D2F ADP 0.00003256 0.42776 19.5767
369 3FIU POP 0.01933 0.40235 19.5767
370 2GK6 ADP 0.003659 0.40224 19.5767
371 1WA5 GTP 0.0000000004659 0.52442 19.8864
372 1VG8 GNP 0.0000000001952 0.79123 20.1058
373 1Z0K GTP 0.0000000002256 0.77839 20.1058
374 1VG0 GDP 0.0000000001074 0.7739 20.1058
375 2CJW GDP 0.00000000003127 0.76828 20.1058
376 5CK5 GDP 0.00000000005704 0.73776 20.1058
377 5HPY GDP 0.00000002225 0.67005 20.1058
378 1OW3 GDP 0.00000002673 0.66633 20.1058
379 1TX4 ALF GDP 0.00000005974 0.54062 20.1058
380 1VG1 GDP 0.00000000009587 0.7667 20.5405
381 1VG9 GDP 0.00000000009883 0.7661 20.5405
382 2BME GNP 0.0000000003114 0.7783 20.6349
383 1M7B GTP 0.00000001422 0.58493 20.6349
384 4K81 GTP 0.0000000003878 0.77977 21.164
385 1Z2A GDP 0.000000002486 0.58709 21.164
386 2BIF ANP 0.0001846 0.5116 21.164
387 2BIF SIN 0.0003153 0.5116 21.164
388 2HT6 GDP 0.00000000002694 0.75074 21.2644
389 3MJH GTP 0.0000000001979 0.59162 21.4286
390 1TU3 GNP 0.0000000002094 0.78661 21.6374
391 5HCN GCP 0.0000000002846 0.74507 21.6931
392 5IRC GDP 0.00000009092 0.6343 21.6931
393 1R2Q GNP 0.0000000008602 0.77844 21.7647
394 1KY3 GDP 0.000000001367 0.72261 22.2222
395 3REF GDP 0.000000006115 0.58262 22.2222
396 1GOT GDP 0.00000006107 0.65924 22.7513
397 3RWO GDP 0.000000003212 0.72942 23.2804
398 3MD0 GDP 0.0000000009426 0.68608 23.8095
399 1TAD ALF 0.00000005615 0.67707 23.8095
400 1TAD GDP 0.00000005615 0.67707 23.8095
401 4NON GDP 0.0000000003296 0.56219 23.8095
402 2GCO GNP 0.000000008249 0.69019 24.3386
403 2GCN GDP 0.00000001916 0.68317 24.3386
404 4R98 GNH 0.0000003644 0.5927 24.3386
405 1FQJ GDP 0.00000002633 0.55033 24.3386
406 1FQK GDP 0.00000008366 0.53565 24.3386
407 1FQK ALF 0.02045 0.40028 24.3386
408 2ODE ALF GDP 0.00000003941 0.68458 24.8677
409 1AZT GSP 0.00000004514 0.6817 24.8677
410 1BH2 GSP 0.00000005506 0.67749 24.8677
411 1Y3A GDP 0.00000005457 0.66452 24.8677
412 2WIC GNP 0.00000003201 0.65116 24.8677
413 2OM2 GDP 0.00000006482 0.56478 24.8677
414 5KDO GDP 0.0000001022 0.5584 24.8677
415 1GP2 GDP 0.0000001235 0.53422 24.8677
416 1K6M AGS 0.00002983 0.53374 24.8677
417 1CS4 GSP 0.00000005381 0.50632 24.8677
418 2HV8 GTP 0.0000000003834 0.77394 25.3968
419 2D7C GTP 0.000000001396 0.74687 25.3968
420 1SVK ALF GDP 0.00000003399 0.69012 25.3968
421 3CX8 GSP 0.00000003061 0.68994 25.3968
422 3AB3 GDP 0.00000002065 0.67843 25.3968
423 1GWN GTP 0.00000003734 0.66626 25.3968
424 4H1V GNP 0.0000006721 0.54952 25.9259
425 3QF7 ANP 0.0001038 0.50111 26
426 3T5G GDP 0.00000000008418 0.77419 27.6243
427 1XTQ GDP 0.0000000001326 0.78942 28.2486
428 2WJH GDP 0.00000001059 0.67316 28.5714
429 2WJH FLC 0.0000004698 0.60141 28.5714
430 2WJG GDP 0.00000001107 0.68337 28.7234
431 2F9L GDP 0.000000004574 0.57434 29.1005
432 3QBT GNP 0.0000000002734 0.58424 29.3103
433 5HR5 ADP 0.00007982 0.50397 29.6296
434 5HR5 FLC 0.005654 0.43657 29.6296
435 1YZQ GNP 0.0000000003173 0.78101 30.1587
436 2A9K GDP 0.000000000313 0.75657 30.1587
437 1X6V ADP 0.0000234 0.41463 30.1587
438 1D5C GDP 0.0000000001337 0.77382 30.2469
439 4DCT GDP 0.0000000004659 0.73527 30.6878
440 1ZC3 GNP 0.0000000005415 0.76977 31.4286
441 1S8F GDP 0.0000000004983 0.77447 31.6384
442 1Z06 GNP 0.00000000006313 0.80834 32.2751
443 1NRJ GTP 0.000000004262 0.71082 32.2751
444 4QOS ADP 0.0004786 0.4499 32.2751
445 1Z0J GTP 0.000000001211 0.55817 32.3529
446 2FH5 GTP 0.000000000009359 0.83648 32.8042
447 2HF9 GSP 0.00000006201 0.59164 32.8042
448 1YVD GNP 0.0000000004147 0.7723 33.1361
449 5UWR GNP 0.0000000002484 0.78617 33.3333
450 5M04 GDP 0.00000000001024 0.76851 33.3333
451 1U8Z GDP 0.0000000008542 0.59587 33.3333
452 1Z0A GDP 0.0000000001331 0.76501 33.8624
453 1OIX GDP 0.0000000007806 0.75905 33.8624
454 2G77 GDP 0.0000000004307 0.67205 33.8624
455 2G77 AF3 0.007167 0.42362 33.8624
456 1OIV GDP 0.000000001097 0.75193 34.3915
457 4C4P GNP 0.0000000006853 0.76481 35.2601
458 3BC1 GNP 0.0000000002283 0.7848 35.4497
459 1Z0F GDP 0.0000000001305 0.76058 35.9788
460 3A1S GDP 0.000000005598 0.68583 35.9788
461 3RAB GNP 0.0000000002403 0.78373 36.0947
462 1YZN GNP 0.0000000006928 0.56071 36.2162
463 1EK0 GNP 0.000000001609 0.7439 36.4706
464 1KMQ GNP 0.00000002578 0.68008 37.037
465 2A5J GDP 0.0000000001708 0.72987 38.6243
466 2FFQ GSP 0.0000000003462 0.77918 39.1813
467 2BCG GDP 0.0000000003053 0.65624 39.6825
468 5UWQ GNP 0.0000000002351 0.5735 40.9091
469 1F6B GDP 0.00000000003941 0.78438 41.7989
470 1Z08 GNP 0.000000001006 0.59829 43.5294
471 1G16 GDP 0.000000002578 0.72457 44.1176
472 1M2O GNP 0.000000001157 0.75081 49.7355
Pocket No.: 2; Query (leader) PDB : 2X77; Ligand: GDP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2x77.bio1) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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