Receptor
PDB id Resolution Class Description Source Keywords
2Y65 2.2 Å NON-ENZYME: MOBILE CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER KINESIN-1 MOTOR DIMER-TAIL COMPLEX DROSOPHILA MELANOGASTER MOTOR PROTEIN
Ref.: THE STRUCTURE OF THE KINESIN-1 MOTOR-TAIL COMPLEX R THE MECHANISM OF AUTOINHIBITION. SCIENCE V. 333 883 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ADP A:603;
B:603;
C:603;
D:603;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
submit data
427.201 C10 H15 N5 O10 P2 c1nc(...
MG A:800;
B:800;
C:800;
D:800;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
submit data
24.305 Mg [Mg+2...
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90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2Y65 2.2 Å NON-ENZYME: MOBILE CRYSTAL STRUCTURE OF DROSOPHILA MELANOGASTER KINESIN-1 MOTOR DIMER-TAIL COMPLEX DROSOPHILA MELANOGASTER MOTOR PROTEIN
Ref.: THE STRUCTURE OF THE KINESIN-1 MOTOR-TAIL COMPLEX R THE MECHANISM OF AUTOINHIBITION. SCIENCE V. 333 883 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 61 families.
1 2Y65 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 2Y65 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 39 families.
1 2Y65 - ADP C10 H15 N5 O10 P2 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ADP; Similar ligands found: 435
No: Ligand ECFP6 Tc MDL keys Tc
1 ADP 1 1
2 ATP 0.9 1
3 A2D 0.895522 0.971831
4 AQP 0.887324 1
5 5FA 0.887324 1
6 AP5 0.884058 0.971831
7 B4P 0.884058 0.971831
8 BA3 0.869565 0.971831
9 AN2 0.84507 0.985915
10 M33 0.833333 0.958333
11 ACQ 0.826667 0.972222
12 A 0.823529 0.971429
13 AMP 0.823529 0.971429
14 ACP 0.821918 0.972222
15 AR6 0.810811 0.971831
16 APR 0.810811 0.971831
17 ANP 0.802632 0.972222
18 AD9 0.8 0.972222
19 AGS 0.8 0.945946
20 SAP 0.8 0.945946
21 ADX 0.783784 0.873418
22 CA0 0.783784 0.945205
23 TAT 0.779221 0.958904
24 AMP MG 0.774648 0.891892
25 50T 0.773333 0.958333
26 ABM 0.763889 0.917808
27 APC 0.763158 0.958904
28 PRX 0.763158 0.893333
29 ATF 0.759494 0.958904
30 A22 0.753086 0.985915
31 A12 0.743243 0.958904
32 AP2 0.743243 0.958904
33 ADP MG 0.736842 0.905405
34 SRA 0.736111 0.918919
35 ADQ 0.73494 0.945205
36 25L 0.732558 0.985915
37 ADP BEF 0.727273 0.881579
38 BEF ADP 0.727273 0.881579
39 5AL 0.725 0.931507
40 2A5 0.717949 0.918919
41 A1R 0.714286 0.907895
42 AU1 0.714286 0.972222
43 ADP PO3 0.708861 0.943662
44 PAP 0.708861 0.985714
45 ATR 0.708861 0.971429
46 SRP 0.707317 0.906667
47 7D3 0.706667 0.905405
48 25A 0.702381 0.971831
49 ATP MG 0.7 0.905405
50 OAD 0.697674 0.945205
51 RBY 0.6875 0.932432
52 ADV 0.6875 0.932432
53 00A 0.686047 0.883117
54 5SV 0.682353 0.848101
55 8QN 0.682353 0.931507
56 OOB 0.682353 0.931507
57 3OD 0.681818 0.945205
58 BIS 0.681818 0.933333
59 ADP ALF 0.674699 0.87013
60 ALF ADP 0.674699 0.87013
61 AMO 0.674419 0.932432
62 4AD 0.674419 0.92
63 PAJ 0.674419 0.884615
64 GAP 0.670732 0.893333
65 MAP 0.670588 0.945946
66 DLL 0.666667 0.931507
67 ANP MG 0.666667 0.894737
68 VO4 ADP 0.666667 0.931507
69 AHX 0.666667 0.896104
70 ADP VO4 0.666667 0.931507
71 PTJ 0.662921 0.896104
72 3UK 0.659091 0.918919
73 SON 0.658228 0.932432
74 LAD 0.651685 0.860759
75 WAQ 0.651685 0.883117
76 PR8 0.651685 0.85
77 ITT 0.65 0.943662
78 7D4 0.65 0.905405
79 G5P 0.648936 0.921053
80 RAB 0.647059 0.84507
81 ADN 0.647059 0.84507
82 XYA 0.647059 0.84507
83 TXA 0.644444 0.932432
84 1ZZ 0.644444 0.839506
85 ME8 0.644444 0.839506
86 NB8 0.644444 0.896104
87 FYA 0.644444 0.905405
88 6AD 0.642857 0.909091
89 ADP BMA 0.640449 0.918919
90 G3A 0.638298 0.921053
91 DAL AMP 0.632184 0.905405
92 AFH 0.631579 0.884615
93 9SN 0.630435 0.871795
94 GTA 0.625 0.886076
95 YAP 0.623656 0.894737
96 FA5 0.623656 0.906667
97 UP5 0.622449 0.92
98 XAH 0.617021 0.839506
99 AV2 0.616279 0.917808
100 AOC 0.615385 0.821918
101 48N 0.612245 0.896104
102 4UV 0.610526 0.894737
103 TXD 0.606061 0.907895
104 DND 0.606061 0.932432
105 NAX 0.606061 0.873418
106 NXX 0.606061 0.932432
107 NAI 0.606061 0.907895
108 6V0 0.606061 0.896104
109 5N5 0.605634 0.819444
110 5AS 0.604938 0.77907
111 A4P 0.60396 0.843373
112 DAT 0.60241 0.905405
113 A2R 0.602273 0.985915
114 TXE 0.6 0.907895
115 OMR 0.6 0.851852
116 4UU 0.597938 0.894737
117 A A 0.597826 0.944444
118 A4D 0.597222 0.819444
119 5CD 0.597222 0.805556
120 AP0 0.594059 0.896104
121 4TC 0.594059 0.896104
122 A3P 0.592593 0.971429
123 139 0.592233 0.873418
124 T5A 0.592233 0.841463
125 7D5 0.592105 0.878378
126 ATP A A A 0.589474 0.930556
127 LAQ 0.585859 0.839506
128 MYR AMP 0.585106 0.817073
129 YLP 0.58 0.819277
130 UPA 0.578431 0.907895
131 7DD 0.578313 0.985714
132 ADJ 0.576923 0.851852
133 3AM 0.576923 0.929577
134 COD 0.575472 0.811765
135 NAD 0.575472 0.931507
136 3AT 0.574713 0.971831
137 JB6 0.574468 0.883117
138 4UW 0.574257 0.860759
139 EP4 0.573333 0.753247
140 A2P 0.573171 0.957143
141 CNA 0.571429 0.932432
142 TYM 0.568627 0.906667
143 PPS 0.568182 0.873418
144 TYR AMP 0.56701 0.881579
145 DTA 0.565789 0.786667
146 M2T 0.565789 0.734177
147 AR6 AR6 0.565657 0.917808
148 A3D 0.564815 0.918919
149 3DH 0.564103 0.773333
150 G5A 0.563218 0.77907
151 YLB 0.563107 0.819277
152 YLC 0.563107 0.839506
153 AMP DBH 0.561224 0.893333
154 MTA 0.558442 0.773333
155 DTP 0.556818 0.905405
156 AHZ 0.554455 0.817073
157 NA7 0.553191 0.958904
158 IOT 0.552381 0.831325
159 7MD 0.55 0.8625
160 ZAS 0.55 0.766234
161 IMO 0.548781 0.929577
162 YLA 0.54717 0.819277
163 NAE 0.544643 0.894737
164 TAD 0.544554 0.884615
165 A5A 0.544444 0.807229
166 2AM 0.544304 0.943662
167 TSB 0.543478 0.819277
168 6RE 0.54321 0.759494
169 AYB 0.542056 0.809524
170 NAQ 0.539823 0.871795
171 V3L 0.539326 0.971831
172 ARG AMP 0.539216 0.829268
173 AF3 ADP 3PG 0.538462 0.8375
174 SSA 0.538462 0.8
175 LA8 ALF 3PG 0.538462 0.8375
176 ALF ADP 3PG 0.538462 0.8375
177 ZID 0.535088 0.918919
178 LPA AMP 0.533981 0.817073
179 54H 0.532609 0.788235
180 52H 0.532609 0.77907
181 VMS 0.532609 0.788235
182 BTX 0.53211 0.841463
183 J7C 0.53012 0.769231
184 A3N 0.53012 0.786667
185 5X8 0.528736 0.763158
186 BT5 0.527273 0.831325
187 5CA 0.526882 0.8
188 53H 0.526882 0.77907
189 ARU 0.526316 0.860759
190 EAD 0.525862 0.873418
191 RGT 0.525253 0.958904
192 OVE 0.52439 0.905405
193 S4M 0.52381 0.666667
194 7DT 0.522727 0.985714
195 GDP 0.522222 0.92
196 DDS 0.522222 0.878378
197 AVV 0.521277 0.896104
198 NDE 0.521008 0.932432
199 7MC 0.518868 0.841463
200 DSH 0.518072 0.725
201 MAO 0.517647 0.759036
202 LSS 0.515789 0.761364
203 DSZ 0.515789 0.8
204 NSS 0.515789 0.8
205 P5A 0.515464 0.744444
206 DZD 0.513514 0.884615
207 NVA LMS 0.510417 0.761364
208 12D 0.509615 0.785714
209 NAD IBO 0.509091 0.87013
210 M24 0.508772 0.85
211 YLY 0.508772 0.809524
212 P1H 0.508333 0.851852
213 5AD 0.506849 0.746479
214 GJV 0.505882 0.75
215 LEU LMS 0.505155 0.761364
216 G A A A 0.504505 0.871795
217 4TA 0.504505 0.807229
218 NAJ PZO 0.504425 0.848101
219 KAA 0.5 0.752809
220 NDC 0.5 0.871795
221 7D7 0.5 0.743243
222 71V 0.5 0.907895
223 A3G 0.5 0.8
224 128 0.5 0.776471
225 GSU 0.5 0.77907
226 N0B 0.495726 0.819277
227 NJP 0.495495 0.945946
228 ODP 0.495495 0.909091
229 2SA 0.494624 0.932432
230 6C6 0.494505 0.881579
231 SFG 0.494382 0.75
232 0WD 0.491071 0.921053
233 YSA 0.490196 0.77907
234 PO4 PO4 A A A A PO4 0.489796 0.902778
235 6IA 0.48913 0.8375
236 SAM 0.48913 0.690476
237 A7D 0.488636 0.776316
238 6FA 0.488 0.841463
239 FB0 0.487805 0.804598
240 NAJ PYZ 0.487179 0.85
241 IDP 0.483516 0.918919
242 A5D 0.483516 0.786667
243 SA8 0.483516 0.707317
244 MHZ 0.483146 0.697674
245 PGS 0.483146 0.883117
246 D5M 0.482353 0.878378
247 DA 0.482353 0.878378
248 NEC 0.482353 0.746667
249 NIA 0.481928 0.822785
250 Y3J 0.480519 0.726027
251 FAD 0.480315 0.851852
252 FAS 0.480315 0.851852
253 FDA 0.48 0.833333
254 N6P 0.479592 0.915493
255 GGZ 0.479167 0.825
256 SAH 0.478261 0.74359
257 SAI 0.478261 0.734177
258 NPW 0.477477 0.886076
259 NDP 0.477477 0.921053
260 AAM 0.476744 0.971429
261 AMZ 0.47561 0.916667
262 C2R 0.47561 0.90411
263 A A A 0.474747 0.905405
264 GTP 0.473684 0.92
265 U A G G 0.473684 0.883117
266 SMM 0.473684 0.686047
267 TXP 0.473214 0.921053
268 NZQ 0.473214 0.909091
269 A3S 0.47191 0.810811
270 AMP NAD 0.470588 0.881579
271 SFD 0.46875 0.734043
272 AIR 0.468354 0.901408
273 AAT 0.468085 0.707317
274 EEM 0.468085 0.690476
275 Z5A 0.466667 0.77907
276 7C5 0.466667 0.818182
277 J7V 0.466667 0.833333
278 62F 0.465649 0.8625
279 FAY 0.462121 0.8625
280 ETB 0.461538 0.833333
281 DCA 0.461538 0.823529
282 A3T 0.461538 0.821918
283 A6D 0.46 0.722892
284 A U 0.459459 0.87013
285 6K6 0.459184 0.930556
286 GEK 0.459184 0.7375
287 RFL 0.458647 0.821429
288 S7M 0.458333 0.690476
289 NAP 0.458333 0.945205
290 4YB 0.457944 0.761364
291 WSA 0.454545 0.788235
292 TAP 0.454545 0.907895
293 FNK 0.454545 0.804598
294 COA 0.453782 0.823529
295 0T1 0.453782 0.823529
296 101 0.453488 0.878378
297 XNP 0.452174 0.873418
298 NA0 0.45082 0.932432
299 7RP 0.448276 0.928571
300 GP3 0.446809 0.921053
301 TM1 0.446602 0.77381
302 APU 0.446429 0.894737
303 PUA 0.445378 0.884615
304 V1N 0.443396 0.917808
305 7RA 0.443182 0.957747
306 30N 0.442623 0.752688
307 CAO 0.442623 0.795455
308 AMX 0.442623 0.833333
309 COS 0.442623 0.804598
310 ACK 0.44186 0.861111
311 QQY 0.44186 0.815789
312 649 0.441441 0.744444
313 0UM 0.44 0.698795
314 NHD 0.439655 0.905405
315 CMX 0.439024 0.823529
316 SCO 0.439024 0.823529
317 GCP 0.438776 0.896104
318 8BR 0.438202 0.906667
319 GNH 0.4375 0.907895
320 3AD 0.4375 0.805556
321 62X 0.435644 0.666667
322 ACO 0.435484 0.795455
323 FCX 0.435484 0.795455
324 FAM 0.435484 0.804598
325 GNP 0.434343 0.896104
326 NMX 0.433071 0.76087
327 MGP 0.43299 0.884615
328 PLP AAD 0.432203 0.741573
329 26A 0.432099 0.763158
330 HAX 0.432 0.804598
331 K15 0.431373 0.682353
332 DG1 0.430894 0.921053
333 1DG 0.430894 0.921053
334 QQX 0.430233 0.805195
335 2VA 0.430108 0.8
336 S8M 0.43 0.759494
337 2MC 0.429688 0.769231
338 3KK 0.428571 0.804598
339 6G0 0.428571 0.884615
340 FYN 0.428571 0.823529
341 P5F 0.428571 0.823529
342 NAD BBN 0.428571 0.841463
343 U G A 0.427481 0.839506
344 AS 0.426966 0.833333
345 FAI 0.426966 0.916667
346 RMB 0.426966 0.873239
347 1RB 0.425287 0.885714
348 MCD 0.425197 0.804598
349 OXK 0.425197 0.804598
350 COK 0.425197 0.804598
351 CA6 0.425197 0.729167
352 SOP 0.425197 0.804598
353 G1R 0.424242 0.907895
354 CC5 0.423077 0.816901
355 SXZ 0.423077 0.710843
356 F2N 0.422535 0.813953
357 NAD CJ3 0.422222 0.811765
358 ANZ 0.422018 0.8
359 CMC 0.421875 0.804598
360 CO6 0.421875 0.804598
361 1VU 0.421875 0.795455
362 ZDA 0.421053 0.864865
363 GDD 0.420561 0.884615
364 GKE 0.420561 0.884615
365 GDC 0.420561 0.884615
366 NFD 0.420168 0.883117
367 GSP 0.42 0.873418
368 D3Y 0.42 0.789474
369 MC4 0.419847 0.76087
370 3L1 0.419753 0.773333
371 3D1 0.419753 0.773333
372 FA9 0.41958 0.864198
373 5GP 0.419355 0.906667
374 G 0.419355 0.906667
375 KB1 0.419048 0.698795
376 SCD 0.418605 0.823529
377 CAJ 0.418605 0.804598
378 2BA 0.417582 0.915493
379 CMP 0.417582 0.901408
380 SO8 0.416667 0.789474
381 N01 0.416667 0.905405
382 VRT 0.416667 0.769231
383 3HC 0.415385 0.813953
384 A1S 0.415385 0.804598
385 BCO 0.415385 0.804598
386 IVC 0.415385 0.813953
387 MLC 0.415385 0.804598
388 1HE 0.415385 0.786517
389 NMN AMP PO4 0.415254 0.87013
390 2FA 0.414634 0.813333
391 MGO 0.414141 0.860759
392 3NZ 0.413462 0.782051
393 MCA 0.412214 0.795455
394 CAA 0.412214 0.813953
395 YE1 0.412214 0.813953
396 COO 0.412214 0.804598
397 GAV 0.411765 0.884615
398 P2P 0.411111 0.902778
399 JLN 0.411111 0.890411
400 ZZB 0.410256 0.77381
401 CNV FAD 0.410072 0.793103
402 SCA 0.409091 0.804598
403 RP1 0.409091 0.842105
404 103 0.409091 0.837838
405 2CP 0.409091 0.795455
406 SP1 0.409091 0.842105
407 PAX 0.408 0.829268
408 FAD NBT 0.407143 0.75
409 NVA 2AD 0.40625 0.74359
410 COW 0.406015 0.795455
411 BYC 0.406015 0.804598
412 2KQ 0.406015 0.786517
413 COF 0.406015 0.786517
414 3CP 0.406015 0.804598
415 IRC 0.406015 0.813953
416 1GZ 0.406015 0.795455
417 HGG 0.406015 0.804598
418 CA8 0.406015 0.729167
419 G2P 0.405941 0.884615
420 SLU 0.404959 0.770115
421 U A C C 0.404959 0.858974
422 RBZ 0.404494 0.849315
423 1CZ 0.404412 0.795455
424 BCA 0.402985 0.795455
425 FAQ 0.402985 0.804598
426 4CA 0.402985 0.795455
427 MTP 0.402439 0.730769
428 8OD 0.402062 0.945205
429 CO7 0.401515 0.804598
430 DAL FAD PER 0.401408 0.809524
431 G2R 0.4 0.884615
432 HXC 0.4 0.786517
433 ENQ 0.4 0.916667
434 GMV 0.4 0.896104
435 GRA 0.4 0.804598
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2Y65; Ligand: ADP; Similar sites found: 429
This union binding pocket(no: 1) in the query (biounit: 2y65.bio1) has 12 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5XCO GDP 0.000001706 0.47588 None
2 1GXU 2HP 0.001141 0.42309 None
3 5UFQ GNP 0.000003846 0.40558 None
4 2VWT PYR 0.01114 0.40416 1.1236
5 1SKQ GDP 0.0000002293 0.56582 1.64384
6 5FG3 GDP 0.0000002902 0.56187 1.64384
7 2DPY ADP 0.00001415 0.51025 1.64384
8 1D2E GDP 0.0000003737 0.49539 1.64384
9 5KSZ GCP 0.00001125 0.46109 1.64384
10 2OG2 MLI 0.00001863 0.56801 1.67131
11 1J99 AND 0.00529 0.45809 1.70648
12 3NKV GNP 0.000001236 0.4166 1.71429
13 4LJ9 ACP 0.00001895 0.47662 1.76991
14 4LC1 GDP 0.000001262 0.52116 1.78042
15 1Y3A GDP 0.00000163 0.42591 1.82371
16 4NON GDP 0.000001239 0.40489 1.92308
17 3B9Q MLI 0.00002972 0.54187 1.98676
18 3UIE ANP 0.000002692 0.47694 2
19 2CBZ ATP 0.0000008656 0.61708 2.1097
20 2IYL GDP 0.00002059 0.47642 2.11268
21 1NST A3P 0.0001657 0.40391 2.15385
22 1CR1 TTP 0.000007493 0.59787 2.19178
23 1MKY GDP 0.0000004231 0.53834 2.19178
24 4ZNL BEF ADP 0.000002632 0.49296 2.19178
25 1FNN ADP 0.000009048 0.4355 2.19178
26 4YDS ATP 0.0000006549 0.56678 2.19298
27 1ZCB GDP 0.000002682 0.40772 2.20994
28 3Q9L ATP 0.0001467 0.40769 2.30769
29 5TSH ADP 0.000004287 0.55048 2.46575
30 5TSH ANP 0.0000008328 0.52687 2.46575
31 1XKV ATP 0.000005489 0.47269 2.46575
32 4RD0 GDP 0.000001543 0.43775 2.46575
33 4NCN GTP 0.000003074 0.42513 2.46575
34 2C9O ADP 0.000009295 0.42416 2.46575
35 1OYY AGS 0.001865 0.40533 2.46575
36 4TMZ GSP 0.000004101 0.42312 2.6087
37 3GJ3 GDP 0.0000005567 0.53378 2.71493
38 3GJ0 GDP 0.0000007463 0.52933 2.71493
39 3GJ5 GDP 0.0000008105 0.51264 2.71493
40 3FKQ ATP 0.00001214 0.4459 2.73973
41 1VHT BA3 0.00005603 0.444 2.75229
42 4B47 GDP 0.0000002606 0.56343 2.75482
43 5BXQ GDP 0.000001125 0.5081 2.77778
44 3EWA ANP 0.000002196 0.50952 2.79503
45 1NJF ADP 0.000001304 0.45561 2.8
46 1NJF AGS 0.00000615 0.42225 2.8
47 1U8Z GDP 0.000006026 0.41443 2.97619
48 1L2T ATP 0.000005208 0.40253 2.97872
49 3GJX GTP 0.00001215 0.59221 3.0137
50 1KK1 GNP 0.0000004443 0.55471 3.0137
51 1XP8 AGS 0.000002119 0.52594 3.0137
52 4R43 GDP 0.000003844 0.50226 3.0137
53 4LYA ATP 0.00000269 0.49176 3.0137
54 3VMF GTP 0.000002283 0.41084 3.0137
55 1IHU AF3 0.00001489 0.41058 3.0137
56 1IHU ADP 0.00001646 0.40236 3.0137
57 4YS0 ADP 0.0002287 0.40186 3.0137
58 1F6B GDP 0.000001434 0.50387 3.0303
59 1G8S MET 0.01257 0.40047 3.04348
60 5X40 ACP 0.00002938 0.56957 3.08219
61 3FYH ADP 0.000004989 0.40277 3.10559
62 5KSP GDP 0.000003685 0.48952 3.15789
63 5BQ5 ADP BEF 0.000006352 0.46829 3.1746
64 4D81 ADP 0.000002383 0.47139 3.18021
65 2WJG GDP 0.0000009368 0.52763 3.19149
66 3VX3 ADP 0.00008034 0.41358 3.22581
67 1Y63 ADP 0.000001033 0.52147 3.26087
68 3TBK ANP 0.0001535 0.46608 3.28767
69 3DZD ADP 0.00006767 0.42812 3.28767
70 5M7P ADP 0.00001041 0.42734 3.28767
71 3WXM GTP 0.000005434 0.40627 3.28767
72 3CV2 OXL 0.007002 0.40511 3.28767
73 1JI0 ATP 0.000005045 0.52907 3.33333
74 1YZG GDP 0.0000009849 0.50913 3.35196
75 4A3U FMN 0.01554 0.41451 3.35196
76 1KO8 6PG 0.00002398 0.42467 3.42857
77 1OFH ADP 0.00000166 0.49096 3.44828
78 4LHW GNP 0.000001307 0.41732 3.44828
79 1LFD GNP 0.000006477 0.4004 3.44828
80 3QKT ANP 0.000006466 0.4006 3.53982
81 3KJI ADP 0.00005202 0.43492 3.54331
82 3WYA GDP 0.0000002165 0.54769 3.56164
83 3P4X ADP 0.000004365 0.51576 3.56164
84 4DCT GDP 0.000001188 0.50837 3.56164
85 3EC1 GDP 0.000008532 0.4805 3.56164
86 5JCP GDP ALF 0.000002175 0.4637 3.56164
87 2FAH GDP 0.000005772 0.45892 3.56164
88 1WDT GTP 0.000001966 0.45613 3.56164
89 4ZKD GDP 0.0000025 0.40862 3.56164
90 2A9K GDP 0.000002677 0.45786 3.58744
91 2D2F ADP 0.00009325 0.51529 3.6
92 2WJH GDP 0.000006008 0.48773 3.61446
93 2WJH FLC 0.00001038 0.46694 3.61446
94 3FVQ ATP 0.00001108 0.41904 3.62117
95 1RRC ADP 0.000001816 0.59479 3.65448
96 5L3V GDP 0.000007497 0.46834 3.67893
97 3B5J 12D 0.000005885 0.52652 3.7037
98 5KUT GDP 0.000001772 0.5011 3.7037
99 5UQW GDP 0.000002485 0.41611 3.7037
100 2WIC GNP 0.0000004066 0.52451 3.74532
101 2GDJ ANP 0.000007964 0.48993 3.78788
102 4WZ6 ATP 0.00000245 0.56352 3.7931
103 2VOH CIT 0.004645 0.40518 3.82166
104 1QXA GLY GLY GLY 0.008536 0.40601 3.82979
105 1YQT ADP 0.000003091 0.55882 3.83562
106 4HSE ADP 0.00000217 0.4939 3.83562
107 1YTM ATP 0.000002838 0.43686 3.83562
108 1Z6T ADP 0.0000147 0.43269 3.83562
109 4OHY ANP 0.00001616 0.40064 3.83562
110 3KTA AP5 0.000002279 0.4644 3.84615
111 2RCN GDP 0.0000006637 0.53205 3.91061
112 4PPF FLC 0.0000006601 0.61499 4
113 2QEN ADP 0.000002016 0.45611 4
114 3QF7 ANP 0.00002333 0.41768 4
115 2ZR9 DTP 0.000002264 0.5099 4.01146
116 2C04 GCP 0.000147 0.41306 4.0404
117 1SVI GDP 0.0000003117 0.56116 4.10256
118 5IRN ADP 0.0000007526 0.48211 4.10959
119 3EZ2 ADP 0.00003459 0.47962 4.10959
120 2JLR ANP 0.00002636 0.43516 4.10959
121 4LPS GDP 0.000001857 0.50237 4.13223
122 3FWY ADP 0.00000372 0.45626 4.14013
123 4V0K GDP 0.000004312 0.41522 4.14201
124 1FP6 ADP 0.00001321 0.44445 4.15225
125 1Z2A GDP 0.0000041 0.42112 4.16667
126 1XX6 ADP 0.0000182 0.47327 4.18848
127 1OIX GDP 0.000001274 0.41788 4.18848
128 1OIV GDP 0.000001901 0.41527 4.18848
129 1KAO GDP 0.000002748 0.45807 4.19162
130 3Q72 GNP 0.000002458 0.52711 4.21687
131 2UZI GTP 0.000006468 0.40225 4.21687
132 2PL3 ADP 0.00003242 0.4816 4.23729
133 4KFU ACP 0.0000009798 0.58149 4.24528
134 3NHB ADP 0.000001758 0.57046 4.24837
135 1ZJ6 G3D 0.000001112 0.50768 4.27807
136 4R2I ANP 0.0006082 0.43985 4.28571
137 1YZN GNP 0.000001601 0.40922 4.32432
138 2ZEJ GDP 0.000001565 0.40628 4.34783
139 1K6M AGS 0.00001351 0.40423 4.38356
140 2CHG ANP 0.00000497 0.44677 4.42478
141 1ZC3 GNP 0.00000497 0.40134 4.42478
142 4WOP CTP 0.00008957 0.42409 4.44444
143 4PX9 ADP 0.000013 0.49629 4.45205
144 3DKP ADP 0.00007664 0.45682 4.4898
145 1S8F GDP 0.000001354 0.49153 4.51977
146 3A4M ADP 0.000003329 0.53655 4.61538
147 3REF GDP 0.000001515 0.43697 4.63918
148 2OZE AGS 0.00001265 0.42837 4.65753
149 5TB5 GDP 0.000002498 0.48186 4.66667
150 1TU3 GNP 0.0000008151 0.42182 4.67836
151 1DS6 GDP 0.000000674 0.5295 4.6875
152 5TAR GDP 0.0000025 0.47017 4.72973
153 3Q85 GNP 0.0000003133 0.54359 4.73373
154 3BER AMP 0.001934 0.40734 4.81928
155 4E03 ADP 0.000009812 0.47651 4.85437
156 3AQ4 GDP 0.000001479 0.50375 4.8913
157 3W5J GDP 0.000002216 0.58426 4.90196
158 1KY3 GDP 0.0000008422 0.48625 4.94506
159 3CNL GNP 0.000001322 0.53773 4.96183
160 3T5G GDP 0.0000003199 0.65556 4.97238
161 2EFE GNH 0.00000359 0.46737 4.97238
162 1JJ7 ADP 0.0000004367 0.6351 5
163 1Z0F GDP 0.000001067 0.50928 5.02793
164 1UAD GNP 0.000004802 0.40268 5.05051
165 1XTQ GDP 0.0000006318 0.43911 5.08475
166 1WQ1 GDP 0.00000483 0.41517 5.08982
167 5GVR LMR 0.000443 0.44823 5.12821
168 1DAR GDP 0.00000166 0.51758 5.20548
169 4IHQ ADP 0.000008223 0.50469 5.20548
170 2O0J ADP 0.003704 0.40647 5.20548
171 2A5J GDP 0.0000005418 0.50574 5.2356
172 1R0X ATP 0.000009508 0.50228 5.24476
173 3RWO GDP 0.000001418 0.41757 5.40541
174 1O3Y GTP 0.00000253 0.42442 5.42169
175 3A1S GDP 0.000008487 0.47804 5.42636
176 2W58 ADP 0.000004114 0.5813 5.44554
177 5HR5 ADP 0.000006204 0.44617 5.47945
178 1S9D GDP 0.0000008702 0.51043 5.4878
179 3N5C GDP 0.0000008147 0.52748 5.55556
180 3T1O GDP 0.000001369 0.49255 5.55556
181 3T12 GDP ALF 0.000003102 0.43069 5.55556
182 1XPJ TLA 0.007808 0.42805 5.55556
183 3PCR GTP 0.000004752 0.41891 5.55556
184 2XTN GTP 0.000006485 0.41354 5.55556
185 5HCN GCP 0.00001407 0.47266 5.74713
186 3CPJ GDP 0.0000008693 0.48702 5.75342
187 1TQ4 GDP 0.0000003476 0.46148 5.75342
188 5M04 GDP 0.0000007824 0.54503 5.83333
189 1G6H ADP 0.0000009524 0.61408 5.83658
190 5IRR GSP 0.00000491 0.43151 5.84416
191 2FNA ADP 0.000002342 0.42801 5.88235
192 1U0J ADP 0.00001617 0.49342 5.99251
193 2WHX ADP 0.000009816 0.53528 6.0274
194 5FTB ANP 0.000008442 0.46516 6.0274
195 2C77 GNP 0.000001247 0.44918 6.0274
196 2C78 GNP 0.0000016 0.43757 6.0274
197 5FHD ADP ALF 0.000009893 0.42199 6.0274
198 4XGU ADP 0.0000728 0.41975 6.0274
199 3AB3 GDP 0.000003524 0.61186 6.09756
200 1OW3 GDP 0.000003227 0.45583 6.21762
201 4R98 GNH 0.000001142 0.5251 6.27306
202 1R6B ADP 0.000002303 0.49894 6.30137
203 4IEE AGS 0.0002209 0.44812 6.30137
204 1GWN GTP 0.0000006596 0.45564 6.34146
205 4YLG GDP 0.000001347 0.4683 6.35838
206 4QM7 GTP 0.000003115 0.50399 6.43275
207 5IRC GDP 0.00001595 0.45271 6.45161
208 1EK0 GNP 0.000001645 0.41595 6.47059
209 2QZ4 ADP 0.000001723 0.48729 6.48855
210 3GJ8 GDP 0.000001007 0.50976 6.52174
211 1KMQ GNP 0.000002982 0.42198 6.52174
212 4KVG GTP 0.000007149 0.40125 6.54762
213 5CK5 GDP 0.00000238 0.52726 6.57534
214 2OBM ADP 0.002064 0.43753 6.62824
215 1MR3 G3D 0.000003463 0.49127 6.62983
216 4XOI GTP 0.000004938 0.40911 6.66667
217 4XSH GSP 0.00000186 0.4527 6.70391
218 1TX4 ALF GDP 0.0000107 0.40947 6.77966
219 3U6B GDP 0.0000002146 0.56679 6.84932
220 4P3Y GDP 0.0000002432 0.56473 6.84932
221 4J0Q GDP 0.0000002606 0.56353 6.84932
222 1D8T GDP 0.0000002576 0.54521 6.84932
223 4G5G GDP 0.0000002658 0.54446 6.84932
224 5JBQ GDP 0.0000003266 0.54133 6.84932
225 3U6K GDP 0.0000004593 0.53675 6.84932
226 5LTJ ADP 0.0000007688 0.51169 6.84932
227 2BVN GNP 0.000001158 0.48142 6.84932
228 5LTJ BEF 0.001216 0.46117 6.84932
229 2FSH ANP 0.0001824 0.45068 6.84932
230 5L3W GDP 0.00003413 0.44653 6.86275
231 1Z0A GDP 0.0000003316 0.51177 6.89655
232 4MKF AP5 0.0001744 0.55214 6.91244
233 2EW1 GNP 0.000005362 0.41789 6.96517
234 3SFV GDP 0.000001234 0.44819 6.97674
235 1M7B GTP 0.0000005715 0.45859 7.06522
236 1YVD GNP 0.000001936 0.41376 7.10059
237 5GOE GDP 0.00000008665 0.53091 7.12329
238 4JLV ADP 0.00146 0.41474 7.12329
239 3QBT GNP 0.000001213 0.41744 7.14286
240 5E95 GDP 0.000003257 0.45456 7.2165
241 3IIJ ADP 0.000002364 0.50842 7.22222
242 5MZN ADP 0.0001267 0.46988 7.39726
243 2GK6 ADP 0.0004314 0.44668 7.39726
244 3M1I GTP 0.000003249 0.40079 7.39726
245 5UWH GNP 0.000003547 0.40076 7.39726
246 5UWI GNP 0.00000368 0.40071 7.39726
247 5DIF GNP 0.000003969 0.40035 7.39726
248 5UWR GNP 0.000003941 0.40021 7.39726
249 5UWW GNP 0.00000427 0.40012 7.39726
250 5UWQ GNP 0.000004104 0.40008 7.39726
251 5UWU GNP 0.000004124 0.40003 7.39726
252 1G7C 5GP 0.0005531 0.4285 7.44681
253 2GCO GNP 0.000001654 0.46646 7.46269
254 2GCN GDP 0.000002358 0.43323 7.46269
255 2QN6 GDP 0.0000002124 0.56763 7.52688
256 2WKQ GTP 0.000002948 0.42019 7.53012
257 1LVG ADP 0.000001256 0.5551 7.57576
258 4AG5 ADP 0.000004082 0.55256 7.67123
259 2XAU ADP 0.000001916 0.487 7.67123
260 5GJC ATP 0.00001407 0.47927 7.67123
261 1RE0 GDP 0.0000006404 0.54848 7.69231
262 1W0J ADP 0.000001023 0.63356 7.72059
263 1W0J ADP BEF 0.00001895 0.57296 7.72059
264 4YMU ATP 0.000004155 0.51581 7.72727
265 3BFV ADP 0.00003117 0.46802 7.74908
266 1PUJ GNP 0.000001848 0.47655 7.80142
267 4OI4 ATP 0.00001769 0.40189 7.82609
268 4TTQ ATP 0.00002418 0.47394 7.90698
269 1NY5 ADP 0.00002297 0.4299 7.94521
270 4IDN GNP 0.000004129 0.4288 7.94521
271 2CK3 ANP 0.00002463 0.41765 8
272 4D0N GDP 0.0000006539 0.53175 8.10811
273 2IXE ATP 0.000009074 0.41167 8.11808
274 1XMV ADP 0.0000006218 0.51194 8.14607
275 1G7S GDP 0.0000003859 0.52184 8.21918
276 1CXZ GSP 0.000003541 0.43234 8.24176
277 4FCW ADP 0.000004772 0.48861 8.36013
278 5JCZ GDP 0.0000006614 0.46703 8.37989
279 1YRB GDP 0.0000004198 0.4927 8.39695
280 1GP2 GDP 0.000003003 0.422 8.4507
281 3BC1 GNP 0.000001017 0.41826 8.47458
282 4LX0 BEF GDP 0.000001082 0.41209 8.47458
283 1Z0J GTP 0.000001208 0.4112 8.47458
284 2F9L GDP 0.0000007563 0.43802 8.54271
285 3KUD GDP 0.000004191 0.43508 8.64198
286 4C4P GNP 0.000001417 0.41025 8.67052
287 1VG0 GDP 0.000001236 0.62691 8.69565
288 1VG8 GNP 0.000001493 0.40899 8.69565
289 2HV8 GTP 0.000001377 0.41675 8.72093
290 5DI3 GNP 0.00000482 0.42711 8.74525
291 1B0U ATP 0.000005258 0.45759 8.77863
292 5J1S ATP 0.000008449 0.40309 8.80282
293 5EE5 GTP 0.000004831 0.4264 8.92019
294 2D7C GTP 0.0000009865 0.41991 8.98204
295 3TNF GNP 0.000001589 0.40192 9.0411
296 5MVR ADP 0.0000009508 0.52365 9.25926
297 3MD0 GDP 0.0000007018 0.54715 9.29577
298 1P7T PYR 0.007256 0.41085 9.31507
299 4U00 ADP 0.0000004555 0.63036 9.42623
300 4ZI2 GNP 0.000002498 0.43287 9.47368
301 4GOJ GNP 0.000001766 0.43564 9.52381
302 2CE7 ADP 0.000002944 0.47665 9.58904
303 4P32 ADP 0.00001785 0.4041 9.63855
304 1VG9 GDP 0.000001013 0.62333 9.72973
305 1VG1 GDP 0.0000003158 0.52611 9.72973
306 5SZH GNP 0.000001308 0.40934 9.80392
307 4RZ3 ADP 0.00003239 0.43075 9.83051
308 2A5F GTP 0.000004093 0.41291 9.84456
309 1RYH GNP 0.000001442 0.4915 9.85222
310 2CJW GDP 0.0000005172 0.53458 9.89583
311 1FZQ GDP 0.0000009518 0.52505 9.94475
312 4KAX GTP 0.000002488 0.43258 10.0592
313 3RAB GNP 0.0000004093 0.42854 10.0592
314 4M9Q GNP 0.000003052 0.43095 10.1322
315 5LB3 ADP 0.00001049 0.50228 10.137
316 3RC3 ANP 0.0003356 0.44155 10.137
317 4PC3 GDP 0.0000009949 0.48139 10.2837
318 5VGR GDP 0.000004513 0.45582 10.411
319 1F5N GNP 0.000003885 0.40329 10.411
320 1HTW ADP 0.0000007663 0.51182 10.7595
321 2J0V GDP 0.0000009164 0.50934 10.8491
322 1G4U GDP 0.00001159 0.43292 10.8696
323 3TK1 GDP 0.000002605 0.54214 10.9091
324 1NF3 GNP 0.000003495 0.40431 10.9375
325 2NGR GDP 0.000001276 0.50355 10.9948
326 1GRN GDP 0.000001784 0.46084 10.9948
327 1A4R GNH 0.000002354 0.45964 10.9948
328 1A4R GDP 0.000002419 0.44894 10.9948
329 4ITR GDP 0.000003576 0.44628 10.9948
330 1SQ5 ADP 0.000001979 0.49669 11.039
331 2WMO GTP 0.000001223 0.49217 11.0526
332 3GJ7 GDP 0.0000007245 0.52993 11.2245
333 1BO4 COA 0.001001 0.41138 11.3095
334 4QOS ADP 0.00001078 0.46027 11.3208
335 2W2X GSP 0.000003696 0.44044 11.3514
336 1G41 ADP 0.000001179 0.49454 11.5068
337 1G6O ADP 0.00000372 0.47246 11.5152
338 4XTR ADP 0.00002059 0.42381 11.5207
339 1FQK GDP 0.000003719 0.41896 11.5646
340 4YC7 GNP 0.000002293 0.43012 11.6022
341 1I4D GDP 0.000000875 0.54311 11.6071
342 2X77 GDP 0.000001663 0.50377 11.6402
343 4P4T GDP 0.0000006176 0.46879 11.6667
344 2IS6 ADP 0.000009899 0.48659 11.7808
345 2PZE ATP 0.00000178 0.59464 12.2271
346 1ZD9 GDP 0.0000006602 0.46487 12.234
347 4U5X GNP 0.000002949 0.44999 12.3596
348 3TKL GTP 0.000001014 0.42499 12.3596
349 2BME GNP 0.00000124 0.41777 12.3656
350 2J59 GTP 0.000003323 0.42276 12.5
351 4HI0 GDP 0.000001179 0.44749 12.5628
352 1E96 GTP 0.000002947 0.4055 13.0208
353 1J2J GTP 0.000003628 0.4224 13.3333
354 3SBD GNP 0.00000428 0.40439 13.369
355 3LXR GDP 0.000001394 0.48874 13.5417
356 3DOE GTP 0.000003444 0.42253 13.5417
357 4BAS GNP 0.000001814 0.43793 13.5678
358 3IO3 ADP 0.00001219 0.42948 13.9726
359 1KSH GDP 0.000002404 0.44321 13.9785
360 2FJU GSP 0.00000353 0.43532 14.0449
361 1Z08 GNP 0.00001533 0.40828 14.1176
362 1HE1 GDP 0.000002773 0.43767 14.2045
363 4DKX GDP 0.0000003201 0.54368 14.3519
364 4D0G GTP 0.000002524 0.43366 14.4928
365 4DID GDP 0.000002145 0.49759 15
366 4A4Z ANP 0.00007663 0.45456 15
367 2ZTS ADP 0.000006231 0.43343 15
368 1GOT GDP 0.000002732 0.42992 15.0685
369 1Z0K GTP 0.000001041 0.43449 15.1163
370 2V7Q ATP 0.0000009984 0.49428 15.1515
371 2V7Q ADP 0.00001747 0.47563 15.1515
372 2BCG GDP 0.0000009879 0.46336 15.534
373 2HT6 GDP 0.000000428 0.55614 16.6667
374 1D5C GDP 0.0000007281 0.47545 17.284
375 1YZQ GNP 0.000001022 0.41326 17.6471
376 2Y8E GNP 0.000001424 0.41756 17.8771
377 3GJ4 GDP 0.0000007916 0.52791 18.1818
378 2FFQ GSP 0.000001432 0.41117 18.7134
379 3WY9 GDP 0.0000001394 0.57403 18.75
380 3B7G ANP 0.00002757 0.4645 19.1304
381 3CH5 GDP 0.0000008536 0.51171 19.2308
382 2HF9 GSP 0.000008681 0.44722 19.469
383 1M7G AV2 0.000000778 0.54413 20
384 4BQS ADP 0.0000008028 0.52593 20
385 4V03 ADP 0.00001465 0.45447 20.2335
386 2G77 GDP 0.0000004618 0.48322 20.7071
387 1Z06 GNP 0.0000008835 0.42883 21.6931
388 3ZIA ATP 0.000001081 0.50764 23.8095
389 3ZIA ADP 0.000001061 0.47995 23.8095
390 2HCJ GDP 0.0000002665 0.56329 24.3243
391 1OXV ANP 0.000002731 0.52192 25
392 5IFS ADP 0.000004045 0.47594 25
393 5E5U MLI 0.0003025 0.46115 25
394 2FH5 GTP 0.000001362 0.45066 25
395 2OM2 GDP 0.000001502 0.44417 25
396 1IN4 ADP 0.000003641 0.4423 25
397 1NRJ GTP 0.00000258 0.44127 25
398 3PQC GDP 0.00000111 0.49332 25.641
399 5KDO GDP 0.000001573 0.44404 25.6757
400 3MJH GTP 0.0000004207 0.42796 26.4706
401 1JJV ATP 0.000009295 0.5342 30
402 2VF7 ADP 0.00000362 0.48733 30
403 3E70 GDP 0.00001377 0.47211 30
404 1G3Q ADP 0.00001153 0.47072 30
405 2D7D ADP 0.0000494 0.4643 30
406 1ION ADP 0.00001577 0.45467 30
407 3DEF GDP 0.00001643 0.44358 30
408 1UPT GTP 0.000004212 0.42715 30
409 3IUY AMP 0.001387 0.41321 30
410 5H67 ATP 0.0004152 0.41193 30
411 2QTV GNP 0.000004054 0.4111 30
412 1M2O GNP 0.00000233 0.41071 30
413 2XTZ GSP 0.000003627 0.40645 30
414 1KC7 PPR 0.01041 0.40372 30
415 1H65 GDP 0.00002847 0.40264 30
416 1FQJ GDP 0.000004766 0.41829 30.9524
417 2W83 GTP 0.000002604 0.42385 32.4675
418 1JWY ADP 0.000000171 0.53573 35
419 5XDR ADP 0.000004833 0.48894 35
420 1JWY GDP 0.000001157 0.48159 35
421 4H1V GNP 0.000021 0.44121 35
422 4KBF AMP 0.0008636 0.42597 35
423 1R4A GNP 0.00001453 0.40163 37.2549
424 2AWN ADP 0.0000001784 0.65999 40
425 4CVN ADP 0.000005932 0.52609 40
426 2ZPA ADP 0.00002162 0.42318 40
427 3RLF ANP 0.000006972 0.4072 40
428 1G16 GDP 0.000001418 0.43971 42.3529
429 3DC4 ADP 0.00000001131 0.6434 47.6744
430 4PJ3 ANP 0.00008854 0.42508 50
Pocket No.: 2; Query (leader) PDB : 2Y65; Ligand: ADP; Similar sites found: 7
This union binding pocket(no: 2) in the query (biounit: 2y65.bio2) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 4DSU GDP 0.0000008272 0.40038 3.1746
2 3BFX A3P 0.00007651 0.40096 4.05405
3 4K81 GTP 0.0000008381 0.40064 4.09357
4 1QHG ATP 0.0002035 0.40009 5.75342
5 5L3S G 0.007144 0.40243 7.09459
6 5UWJ GNP 0.000001035 0.40032 7.39726
7 2J5V PCA 0.01976 0.40418 40
Pocket No.: 3; Query (leader) PDB : 2Y65; Ligand: ADP; Similar sites found: 4
This union binding pocket(no: 3) in the query (biounit: 2y65.bio3) has 13 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2V5K OXM 0.0115 0.40476 1.74216
2 3T34 GDP 0.00005946 0.40129 4.44444
3 1UJ2 ADP 0.000009496 0.40015 7.53968
4 1QHH ATP 0.001747 0.40611 26.9565
Pocket No.: 4; Query (leader) PDB : 2Y65; Ligand: ADP; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 4) in the query (biounit: 2y65.bio3) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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