Receptor
PDB id Resolution Class Description Source Keywords
2YBS 2.32 Å EC: 1.14.11.- JMJD2A COMPLEXED WITH S-2-HYDROXYGLUTARATE AND HISTONE H3K36 PEPTIDE (30-41) HOMO SAPIENS OXIDOREDUCTASE-PEPTIDE COMPLEX NON-HEME IRON DIOXYGENASE STRANDED BETA HELIX DSBH FACIAL TRIAD METAL BINDING PROTEPIGENETIC AND TRANSCRIPTION REGULATION CHROMATIN REGULATOHYDROXYLATION
Ref.: THE ONCOMETABOLITE 2-HYDROXYGLUTARATE INHIBITS HIST LYSINE DEMETHYLASES. EMBO REP. V. 12 463 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
GOL A:1358;
 Invalid;
 none;
 submit data
92.094 C3 H8 O3 C(C(C...
NI A:1356;
B:1356;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
58.693 Ni [Ni+2...
S2G A:1359;
B:1358;
 Valid;
Valid;
 none;
none;
 submit data
148.114 C5 H8 O5 C(CC(...
ZN A:1357;
B:1357;
 Part of Protein;
Part of Protein;
 none;
none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2YBP 2.02 Å EC: 1.14.11.- JMJD2A COMPLEXED WITH R-2-HYDROXYGLUTARATE AND HISTONE H3K36 PEPTIDE (30-41) HOMO SAPIENS OXIDOREDUCTASE-PEPTIDE COMPLEX NON-HEME IRON DIOXYGENASE STRANDED BETA HELIX DSBH FACIAL TRIAD METAL BINDING PROTEPIGENETIC AND TRANSCRIPTION REGULATION CHROMATIN REGULATOHYDROXYLATION
Ref.: THE ONCOMETABOLITE 2-HYDROXYGLUTARATE INHIBITS HIST LYSINE DEMETHYLASES. EMBO REP. V. 12 463 2011
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 43 families.
1 2YBP - 2HG C5 H8 O5 C(CC(=O)O)....
2 2YBS - S2G C5 H8 O5 C(CC(=O)O)....
70% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 31 families.
1 2YBP - 2HG C5 H8 O5 C(CC(=O)O)....
2 2YBS - S2G C5 H8 O5 C(CC(=O)O)....
3 2OS2 - OGA C4 H5 N O5 C(C(=O)O)N....
4 2Q8E - OGA C4 H5 N O5 C(C(=O)O)N....
5 2Q8D - SIN C4 H6 O4 C(CC(=O)O)....
6 2PXJ - OGA C4 H5 N O5 C(C(=O)O)N....
7 2P5B - OGA C4 H5 N O5 C(C(=O)O)N....
50% Homology Family (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 28 families.
1 2YBP - 2HG C5 H8 O5 C(CC(=O)O)....
2 2YBS - S2G C5 H8 O5 C(CC(=O)O)....
3 2OS2 - OGA C4 H5 N O5 C(C(=O)O)N....
4 2Q8E - OGA C4 H5 N O5 C(C(=O)O)N....
5 2Q8D - SIN C4 H6 O4 C(CC(=O)O)....
6 2PXJ - OGA C4 H5 N O5 C(C(=O)O)N....
7 2P5B - OGA C4 H5 N O5 C(C(=O)O)N....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: S2G; Similar ligands found: 12
No: Ligand ECFP6 Tc MDL keys Tc
1 2HG 1 1
2 S2G 1 1
3 MLT 0.461538 0.809524
4 LMR 0.461538 0.809524
5 2RH 0.444444 0.652174
6 DGY 0.44 0.666667
7 GLU 0.433333 0.653846
8 GGL 0.433333 0.653846
9 9ON 0.433333 0.727273
10 DGL 0.433333 0.653846
11 HOC 0.411765 0.62963
12 HCT 0.40625 0.8
Similar Ligands (3D)
Ligand no: 1; Ligand: S2G; Similar ligands found: 846
No: Ligand Similarity coefficient
1 AKG 1.0000
2 OGA 1.0000
3 2IT 0.9959
4 ONL 0.9956
5 GLN 0.9942
6 ZGL 0.9853
7 URQ 0.9801
8 MHO 0.9741
9 2FT 0.9702
10 OKG 0.9690
11 GUA 0.9689
12 ORN 0.9654
13 LEU 0.9634
14 ASP 0.9626
15 URO 0.9619
16 DGN 0.9608
17 URP 0.9601
18 NLE 0.9582
19 DZA 0.9578
20 ASN 0.9576
21 MET 0.9571
22 PHB 0.9567
23 8GL 0.9565
24 HGA 0.9564
25 NPO 0.9563
26 MUC 0.9556
27 OEG 0.9550
28 TIH 0.9549
29 TYL 0.9546
30 3PG 0.9543
31 SME 0.9537
32 PBZ 0.9536
33 RUJ 0.9531
34 HIS 0.9524
35 HHI 0.9524
36 PAB 0.9516
37 MSL 0.9500
38 DIR 0.9497
39 GLY GLY 0.9492
40 PHU 0.9489
41 HPV 0.9485
42 KMT 0.9483
43 M4T 0.9479
44 XIZ 0.9478
45 LYS 0.9467
46 TLA 0.9464
47 NF3 0.9463
48 OAA 0.9455
49 3LR 0.9450
50 SEP 0.9450
51 PAC 0.9441
52 0VT 0.9440
53 7OD 0.9433
54 J9N 0.9430
55 IZC 0.9426
56 HBD 0.9424
57 R9M 0.9423
58 DE5 0.9420
59 AC6 0.9417
60 7BC 0.9416
61 2HC 0.9412
62 7C3 0.9412
63 DLY 0.9411
64 HL5 0.9408
65 PO6 0.9407
66 P72 0.9405
67 9J3 0.9403
68 PZI 0.9400
69 2CO 0.9390
70 INO 0.9390
71 4MA 0.9386
72 AL0 0.9379
73 SYM 0.9379
74 OK7 0.9377
75 GRO 0.9376
76 QY9 0.9372
77 BHU 0.9370
78 OSE 0.9368
79 DHI 0.9363
80 AOT 0.9361
81 5XB 0.9356
82 SHO 0.9356
83 PGA 0.9355
84 0L1 0.9354
85 O45 0.9354
86 DYT 0.9354
87 R20 0.9353
88 268 0.9352
89 TCA 0.9351
90 TAR 0.9350
91 HC4 0.9346
92 264 0.9344
93 DHB 0.9341
94 PEP 0.9340
95 ALA ALA 0.9340
96 SRT 0.9339
97 HG3 0.9336
98 PNZ 0.9336
99 MSR 0.9335
100 ESX 0.9332
101 NM2 0.9331
102 SNU 0.9329
103 6NA 0.9327
104 Z82 0.9327
105 JB8 0.9326
106 1Y6 0.9324
107 DAL DAL 0.9324
108 ISZ 0.9323
109 URS 0.9320
110 A5E 0.9316
111 GPJ 0.9315
112 93K 0.9315
113 EOU 0.9314
114 TZF 0.9314
115 1F1 0.9313
116 M45 0.9312
117 JDN 0.9312
118 JAW 0.9312
119 4WL 0.9312
120 0HN 0.9311
121 2ZM 0.9309
122 3A9 0.9308
123 CPZ 0.9307
124 SPA 0.9307
125 9X6 0.9306
126 K6H 0.9306
127 2HU 0.9303
128 BNL 0.9299
129 HTX 0.9298
130 4P5 0.9298
131 ABI 0.9297
132 BNF 0.9290
133 I4B 0.9289
134 6NI 0.9288
135 IXW 0.9288
136 PIM 0.9288
137 6NT 0.9286
138 173 0.9286
139 NM3 0.9285
140 S2P 0.9284
141 3NY 0.9283
142 5NI 0.9281
143 650 0.9281
144 BEZ 0.9280
145 3HP 0.9276
146 SMN 0.9276
147 LYN 0.9276
148 4ZA 0.9276
149 K34 0.9272
150 CXF 0.9272
151 NIZ 0.9271
152 DAV 0.9270
153 PGH 0.9268
154 36Y 0.9268
155 GPF 0.9265
156 ICB 0.9263
157 ONH 0.9263
158 C1M 0.9261
159 CHH 0.9260
160 FK8 0.9260
161 BZ2 0.9259
162 CFI 0.9258
163 4HP 0.9256
164 HY1 0.9255
165 AHN 0.9254
166 BHO 0.9254
167 SW7 0.9252
168 MED 0.9252
169 KDG 0.9249
170 MZT 0.9247
171 CCE 0.9244
172 97T 0.9243
173 3SL 0.9240
174 258 0.9240
175 MEQ 0.9240
176 ESP 0.9239
177 X1S 0.9239
178 0HO 0.9237
179 BHH 0.9236
180 ACA 0.9235
181 L5V 0.9233
182 HSO 0.9233
183 AEG 0.9232
184 ASC 0.9231
185 ANN 0.9230
186 PPY 0.9230
187 I38 0.9229
188 LTL 0.9229
189 SIN 0.9223
190 CCD 0.9222
191 HQJ 0.9221
192 7UC 0.9221
193 G3P 0.9220
194 HCI 0.9220
195 CCU 0.9219
196 HSE 0.9218
197 ACH 0.9216
198 HX4 0.9216
199 ZBT 0.9213
200 13P 0.9213
201 BPN 0.9212
202 49F 0.9211
203 HSM 0.9211
204 BEN 0.9210
205 1L5 0.9210
206 PG3 0.9210
207 CHB 0.9209
208 449 0.9209
209 F9P 0.9208
210 4BZ 0.9208
211 3S5 0.9207
212 9TW 0.9206
213 AMH 0.9205
214 MPV 0.9203
215 GZ3 0.9203
216 RAT 0.9201
217 HBA 0.9200
218 B40 0.9199
219 P9P 0.9199
220 SPV 0.9198
221 J0Z 0.9198
222 FBM 0.9197
223 KMH 0.9196
224 0BP 0.9193
225 8OZ 0.9193
226 DOB 0.9189
227 7VP 0.9189
228 OOG 0.9183
229 SKJ 0.9182
230 PEL 0.9182
231 PIY 0.9181
232 XRG 0.9180
233 E5X 0.9180
234 2HO 0.9179
235 HDH 0.9177
236 NYL 0.9177
237 MPJ 0.9177
238 FAN 0.9175
239 PHE 0.9174
240 6JN 0.9174
241 SHV 0.9174
242 CUW 0.9174
243 IHB 0.9172
244 FUM 0.9171
245 G3H 0.9168
246 DHS 0.9167
247 9RW 0.9166
248 J9Q 0.9163
249 B85 0.9163
250 M3P 0.9163
251 NFA 0.9161
252 QSB 0.9161
253 OTR 0.9158
254 CYX 0.9156
255 PMF 0.9156
256 R9S 0.9156
257 717 0.9155
258 4FA 0.9154
259 B3U 0.9153
260 L99 0.9151
261 N4B 0.9151
262 KOJ 0.9148
263 P7Y 0.9146
264 PBC 0.9146
265 TSU 0.9145
266 FHB 0.9145
267 LFC 0.9145
268 MSE 0.9144
269 ITN 0.9144
270 7WG 0.9142
271 F4E 0.9141
272 FCR 0.9140
273 DAB 0.9140
274 XDK 0.9140
275 MHN 0.9138
276 UN1 0.9135
277 SAN 0.9135
278 5CU 0.9133
279 4LR 0.9133
280 826 0.9133
281 DPN 0.9133
282 GOJ 0.9130
283 11C 0.9130
284 SYC 0.9127
285 BHA 0.9126
286 3YP 0.9126
287 COI 0.9126
288 M3H 0.9125
289 2BX 0.9125
290 AG2 0.9125
291 GJZ 0.9125
292 NNO 0.9123
293 ILE 0.9122
294 HF2 0.9121
295 JYD 0.9119
296 ENV 0.9119
297 IP8 0.9118
298 4NC 0.9117
299 PH3 0.9116
300 PRA 0.9114
301 S8V 0.9114
302 X0V 0.9113
303 BZ3 0.9112
304 9YT 0.9110
305 51F 0.9110
306 4NM 0.9109
307 J9T 0.9108
308 M6H 0.9106
309 2FM 0.9105
310 GWM 0.9105
311 TZE 0.9104
312 YRL 0.9104
313 N6C 0.9104
314 5HY 0.9103
315 FA0 0.9103
316 E4P 0.9102
317 TZL 0.9102
318 TPA 0.9101
319 8EW 0.9101
320 L22 0.9100
321 GZ2 0.9100
322 AMS 0.9098
323 NCA 0.9097
324 RBL 0.9097
325 GO2 0.9097
326 A3M 0.9095
327 AT3 0.9094
328 3OL 0.9093
329 3OM 0.9093
330 TIU 0.9093
331 FQI 0.9093
332 BAM 0.9092
333 3HG 0.9091
334 152 0.9091
335 TYR 0.9090
336 271 0.9089
337 6TZ 0.9088
338 HPS 0.9088
339 PD2 0.9088
340 NLP 0.9086
341 PPR 0.9083
342 P80 0.9082
343 HHH 0.9081
344 MYJ 0.9080
345 8SZ 0.9079
346 GP9 0.9077
347 JF6 0.9076
348 PEA 0.9076
349 XYH 0.9075
350 7O4 0.9074
351 CEE 0.9073
352 2AL 0.9072
353 HMS 0.9072
354 IWT 0.9069
355 YZM 0.9068
356 KTA 0.9068
357 UNU 0.9068
358 SD4 0.9066
359 PSE 0.9066
360 A29 0.9066
361 CXP 0.9066
362 5XA 0.9064
363 GVM 0.9064
364 HIC 0.9063
365 6FZ 0.9063
366 4M0 0.9061
367 SHI 0.9061
368 52C 0.9059
369 4VP 0.9058
370 NIO 0.9058
371 0V5 0.9057
372 I1E 0.9057
373 7N0 0.9057
374 SLZ 0.9057
375 GAB 0.9056
376 98J 0.9056
377 RMN 0.9056
378 TEO 0.9054
379 DHK 0.9053
380 RSO 0.9051
381 SOL 0.9051
382 MAJ 0.9048
383 1DJ 0.9048
384 2BG 0.9047
385 DYA 0.9047
386 VKC 0.9046
387 E1T 0.9045
388 NCT 0.9043
389 LUQ 0.9041
390 NVA 0.9040
391 XIY 0.9039
392 Q9Z 0.9038
393 APG 0.9036
394 1GP 0.9035
395 FP1 0.9035
396 2LP 0.9034
397 ES2 0.9032
398 7A8 0.9028
399 FOC 0.9027
400 4V2 0.9026
401 5LA 0.9026
402 JZ4 0.9025
403 DQY 0.9025
404 0OC 0.9024
405 KTW 0.9024
406 RBJ 0.9022
407 3OC 0.9022
408 AHB 0.9022
409 53C 0.9021
410 HFA 0.9020
411 6PC 0.9019
412 4FH 0.9019
413 3HM 0.9019
414 QMP 0.9017
415 AEF 0.9017
416 PBA 0.9016
417 1M2 0.9016
418 XX2 0.9016
419 2F6 0.9016
420 X1R 0.9015
421 4A3 0.9015
422 1BN 0.9015
423 3PP 0.9015
424 JLZ 0.9014
425 MAH 0.9013
426 RUY 0.9011
427 GDE 0.9011
428 GVG 0.9010
429 MNN 0.9009
430 C82 0.9009
431 PJW 0.9009
432 OVM 0.9009
433 069 0.9008
434 FOM 0.9008
435 3MB 0.9007
436 2D8 0.9007
437 1A7 0.9006
438 4MV 0.9005
439 CH9 0.9004
440 LT1 0.9003
441 MPH 0.9002
442 1SA 0.9001
443 PAH 0.9000
444 8WO 0.9000
445 C5A 0.9000
446 HA5 0.8999
447 9FE 0.8999
448 15N 0.8999
449 UGC 0.8998
450 129 0.8998
451 PDC 0.8997
452 5OB 0.8995
453 OVV 0.8995
454 363 0.8994
455 XLS 0.8991
456 SHF 0.8990
457 2PG 0.8989
458 FEH 0.8988
459 LNR 0.8986
460 LDP 0.8983
461 FBJ 0.8983
462 259 0.8983
463 XYL 0.8981
464 R2P 0.8981
465 HPN 0.8981
466 FIX 0.8980
467 RD4 0.8980
468 PEQ 0.8980
469 PZM 0.8980
470 FBB 0.8979
471 N3W 0.8977
472 3HB 0.8977
473 OW7 0.8976
474 4J8 0.8975
475 DHM 0.8974
476 H95 0.8972
477 TYE 0.8972
478 QSH 0.8970
479 6KT 0.8969
480 NWH 0.8969
481 DHY 0.8969
482 9X7 0.8969
483 M6W 0.8968
484 5XC 0.8968
485 4TB 0.8967
486 8G0 0.8965
487 RTK 0.8965
488 4LW 0.8964
489 5NU 0.8963
490 AAS 0.8963
491 ESI 0.8963
492 4PN 0.8963
493 HL4 0.8962
494 VNL 0.8962
495 DHR 0.8960
496 HIO 0.8958
497 ROR 0.8958
498 174 0.8958
499 P81 0.8957
500 GVY 0.8957
501 4LV 0.8956
502 4JT 0.8955
503 RNT 0.8954
504 0W1 0.8953
505 HYA 0.8953
506 VAH 0.8952
507 PC 0.8951
508 1X4 0.8950
509 DAR 0.8949
510 40E 0.8949
511 16D 0.8948
512 O8Y 0.8946
513 3C4 0.8943
514 GCO 0.8942
515 PLU 0.8941
516 CXH 0.8941
517 K2T 0.8941
518 LY0 0.8940
519 K6V 0.8939
520 1SH 0.8938
521 JRB 0.8937
522 3PF 0.8937
523 263 0.8936
524 JZ7 0.8935
525 4JQ 0.8935
526 PG0 0.8934
527 EHM 0.8931
528 X48 0.8930
529 FBS 0.8929
530 K7M 0.8929
531 PKU 0.8929
532 94W 0.8927
533 BSX 0.8927
534 HCS 0.8926
535 2EH 0.8925
536 SSN 0.8923
537 SKM 0.8921
538 HDL 0.8921
539 TT4 0.8921
540 MES 0.8918
541 AMQ 0.8917
542 XBT 0.8914
543 61M 0.8912
544 8NB 0.8909
545 9ZE 0.8909
546 261 0.8908
547 AFS 0.8907
548 N9J 0.8906
549 SOR 0.8906
550 1P8 0.8906
551 GLO 0.8904
552 92G 0.8904
553 FUD 0.8902
554 MLE 0.8900
555 9CA 0.8899
556 HX2 0.8898
557 DAS 0.8897
558 NMG 0.8897
559 DS0 0.8896
560 EVF 0.8896
561 1IT 0.8895
562 3QM 0.8894
563 69O 0.8894
564 8U3 0.8893
565 92K 0.8892
566 92P 0.8892
567 9SE 0.8892
568 SKG 0.8892
569 7MW 0.8889
570 4YO 0.8888
571 3NT 0.8888
572 9FL 0.8887
573 ONR 0.8886
574 EKZ 0.8884
575 LNO 0.8883
576 0JD 0.8882
577 4BL 0.8882
578 LSQ 0.8880
579 7MU 0.8879
580 B3M 0.8879
581 Q02 0.8878
582 2O6 0.8878
583 UFV 0.8877
584 41K 0.8877
585 J6W 0.8877
586 54D 0.8874
587 36E 0.8873
588 AX3 0.8873
589 14J 0.8873
590 MR1 0.8872
591 F31 0.8871
592 SYV 0.8870
593 4CS 0.8870
594 4NB 0.8869
595 HBU 0.8868
596 PRY 0.8866
597 Q03 0.8866
598 42J 0.8864
599 1LN 0.8862
600 FB2 0.8861
601 PBN 0.8860
602 12T 0.8859
603 4BY 0.8859
604 ICO 0.8859
605 RNO 0.8858
606 CS2 0.8858
607 3AL 0.8854
608 TAG 0.8853
609 SHA 0.8853
610 WCE 0.8851
611 4SX 0.8851
612 CWJ 0.8850
613 XUL 0.8848
614 PRZ 0.8847
615 C2Y 0.8846
616 JFJ 0.8844
617 L14 0.8843
618 NSB 0.8843
619 CSS 0.8842
620 1DV 0.8840
621 8XL 0.8839
622 HNK 0.8838
623 SSB 0.8838
624 KPC 0.8836
625 1XA 0.8836
626 IFP 0.8836
627 S24 0.8833
628 MD0 0.8831
629 4XV 0.8831
630 M5E 0.8829
631 TZM 0.8828
632 REL 0.8824
633 RP3 0.8824
634 KTJ 0.8824
635 2QC 0.8823
636 F9Y 0.8823
637 UNJ 0.8821
638 1KA 0.8821
639 LQ2 0.8820
640 PSJ 0.8820
641 RNS 0.8817
642 5WZ 0.8815
643 4I8 0.8814
644 MLZ 0.8814
645 3AB 0.8813
646 OW4 0.8813
647 TPO 0.8812
648 1Z6 0.8810
649 MS9 0.8809
650 0NX 0.8809
651 HNL 0.8808
652 5HN 0.8806
653 TGX 0.8806
654 R67 0.8805
655 4SD 0.8805
656 MEV 0.8805
657 M4S 0.8803
658 3ZB 0.8801
659 P58 0.8801
660 AX7 0.8800
661 OVP 0.8797
662 QFJ 0.8793
663 BPY 0.8792
664 QUS 0.8792
665 DNF 0.8791
666 SNO 0.8791
667 EXD 0.8789
668 FF2 0.8787
669 HNH 0.8786
670 IAC 0.8784
671 HE2 0.8783
672 MQN 0.8782
673 5RN 0.8782
674 23J 0.8782
675 KVP 0.8782
676 A9P 0.8781
677 DXG 0.8780
678 ALE 0.8777
679 8ZE 0.8777
680 H42 0.8777
681 9RH 0.8776
682 1WC 0.8774
683 GLR 0.8772
684 ARG 0.8771
685 CLT 0.8771
686 FF3 0.8769
687 RB5 0.8768
688 GZL 0.8766
689 YPN 0.8766
690 2FX 0.8766
691 HPP 0.8766
692 N2I 0.8766
693 BZJ 0.8765
694 0F9 0.8763
695 BRT 0.8762
696 ABV 0.8762
697 DLT 0.8761
698 AZM 0.8760
699 Q06 0.8759
700 5FX 0.8754
701 ET2 0.8753
702 DER 0.8753
703 DHC 0.8752
704 THE 0.8752
705 492 0.8752
706 2FY 0.8752
707 8GC 0.8751
708 SAF 0.8750
709 XCG 0.8750
710 ODO 0.8750
711 KVV 0.8749
712 NMJ 0.8748
713 M5H 0.8747
714 IVL 0.8747
715 BHL 0.8745
716 TEG 0.8745
717 F98 0.8744
718 EN1 0.8744
719 AC0 0.8744
720 6XA 0.8740
721 FBW 0.8739
722 PPT 0.8737
723 51R 0.8736
724 QDK 0.8736
725 9GB 0.8736
726 DI6 0.8735
727 TMG 0.8734
728 NSD 0.8733
729 D3G 0.8732
730 M4E 0.8732
731 ABU 0.8732
732 SDD 0.8730
733 CFA 0.8729
734 COU 0.8728
735 MTL 0.8727
736 4JC 0.8726
737 DEW 0.8725
738 3BZ 0.8725
739 NNH 0.8725
740 4XS 0.8725
741 ENO 0.8724
742 OCA 0.8724
743 F06 0.8723
744 CK2 0.8723
745 AOS 0.8722
746 FGZ 0.8720
747 4FS 0.8720
748 VXX 0.8719
749 BPW 0.8719
750 LEA 0.8717
751 DTY 0.8717
752 1DU 0.8714
753 SN4 0.8713
754 5RO 0.8712
755 FHC 0.8712
756 F4K 0.8711
757 BRH 0.8710
758 RB0 0.8710
759 S0W 0.8710
760 S0E 0.8710
761 9YL 0.8710
762 HJH 0.8709
763 PJL 0.8709
764 7Q1 0.8708
765 JAE 0.8701
766 DXP 0.8699
767 7QS 0.8696
768 HSX 0.8695
769 RLG 0.8694
770 GLY ALA 0.8692
771 D48 0.8691
772 M1Z 0.8689
773 YTX 0.8688
774 OCH 0.8687
775 4XF 0.8687
776 S7A 0.8684
777 03V 0.8684
778 4XR 0.8684
779 LLH 0.8682
780 DEZ 0.8681
781 1CO 0.8678
782 KPA 0.8675
783 N7I 0.8670
784 8WT 0.8668
785 CTV 0.8668
786 6RQ 0.8667
787 N2Z 0.8667
788 2AQ 0.8666
789 Q07 0.8666
790 80G 0.8662
791 64Z 0.8662
792 S7J 0.8658
793 DII 0.8656
794 OCT 0.8655
795 CLU 0.8651
796 LPK 0.8649
797 CLW 0.8647
798 ES5 0.8647
799 SQ4 0.8645
800 Q04 0.8639
801 3CR 0.8634
802 H8N 0.8634
803 5OO 0.8632
804 36R 0.8627
805 1VK 0.8627
806 I3E 0.8625
807 2MI 0.8624
808 15E 0.8623
809 GBN 0.8623
810 8K2 0.8621
811 JND 0.8615
812 0FK 0.8615
813 505 0.8610
814 G3E 0.8607
815 1P3 0.8603
816 FBF 0.8599
817 DPF 0.8597
818 F69 0.8596
819 4BF 0.8591
820 Z5P 0.8587
821 270 0.8586
822 56D 0.8586
823 4JM 0.8586
824 1SP 0.8584
825 AVI 0.8582
826 3MV 0.8581
827 VGD 0.8579
828 50C 0.8578
829 4Z4 0.8575
830 M44 0.8573
831 J5I 0.8571
832 DIN 0.8569
833 LR5 0.8565
834 6HO 0.8565
835 SQ7 0.8565
836 G2H 0.8561
837 3AE 0.8560
838 SE2 0.8552
839 ABF 0.8551
840 8NX 0.8545
841 MMS 0.8539
842 KBZ 0.8537
843 GZQ 0.8524
844 VM1 0.8523
845 GLY GLY GLY 0.8521
846 RM1 0.8512
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2YBP; Ligand: 2HG; Similar sites found with APoc: 2
This union binding pocket(no: 1) in the query (biounit: 2ybp.bio1) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 6IP0 AKG 40.9449
2 4IGQ THR M3L GLN 41.3889
Pocket No.: 2; Query (leader) PDB : 2YBP; Ligand: 2HG; Similar sites found with APoc: 2
This union binding pocket(no: 2) in the query (biounit: 2ybp.bio2) has 13 residues
No: Leader PDB Ligand Sequence Similarity
1 6IP0 AKG 40.9449
2 4IGQ THR M3L GLN 41.3889
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