Receptor
PDB id Resolution Class Description Source Keywords
2YX1 2.2 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF M.JANNASCHII TRNA M1G37 METHYLTRANSFERA METHANOCALDOCOCCUS JANNASCHII METHYL TRANSFERASE TRNA MODIFICATION ENZYME TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF ARCHAEAL TRNA(M(1)G37)METHYLTR ATRM5. PROTEINS V. 72 1274 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
SFG A:401;
B:402;
Valid;
Valid;
none;
none;
submit data
381.387 C15 H23 N7 O5 c1nc(...
ZN A:501;
A:502;
A:503;
A:504;
B:505;
B:506;
B:507;
B:508;
B:509;
B:510;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
Part of Protein;
none;
none;
none;
none;
none;
none;
none;
none;
none;
none;
submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2YX1 2.2 Å NON-ENZYME: OTHER CRYSTAL STRUCTURE OF M.JANNASCHII TRNA M1G37 METHYLTRANSFERA METHANOCALDOCOCCUS JANNASCHII METHYL TRANSFERASE TRNA MODIFICATION ENZYME TRANSFERASE
Ref.: CRYSTAL STRUCTURE OF ARCHAEAL TRNA(M(1)G37)METHYLTR ATRM5. PROTEINS V. 72 1274 2008
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 2YX1 - SFG C15 H23 N7 O5 c1nc(c2c(n....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 2YX1 - SFG C15 H23 N7 O5 c1nc(c2c(n....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 2YX1 - SFG C15 H23 N7 O5 c1nc(c2c(n....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SFG; Similar ligands found: 218
No: Ligand ECFP6 Tc MDL keys Tc
1 SFG 1 1
2 0UM 0.689655 0.887324
3 SAI 0.654762 0.940298
4 SA8 0.642857 0.9
5 SAH 0.635294 0.954545
6 EEM 0.62069 0.875
7 5X8 0.619048 0.924242
8 S7M 0.606742 0.875
9 RAB 0.597222 0.850746
10 XYA 0.597222 0.850746
11 ADN 0.597222 0.850746
12 5CD 0.594595 0.863636
13 5N5 0.581081 0.850746
14 62X 0.574468 0.84
15 A4D 0.573333 0.850746
16 K15 0.568421 0.863014
17 DTA 0.564103 0.84058
18 6RE 0.560976 0.833333
19 SAM 0.555556 0.875
20 EP4 0.551282 0.802817
21 KB1 0.55102 0.887324
22 M2T 0.544304 0.780822
23 SMM 0.537634 0.84
24 MTA 0.5375 0.826087
25 ZAS 0.53012 0.816901
26 A 0.53012 0.77027
27 AMP 0.53012 0.77027
28 J7C 0.529412 0.84507
29 3DH 0.52439 0.826087
30 GJV 0.523256 0.821918
31 SON 0.522727 0.813333
32 0XU 0.522222 0.938462
33 SRP 0.521277 0.813333
34 SSA 0.521277 0.697674
35 AMP MG 0.517647 0.75
36 AOC 0.517647 0.826087
37 CA0 0.516854 0.776316
38 5AL 0.516129 0.786667
39 AMO 0.515464 0.813333
40 DSZ 0.515464 0.717647
41 GSU 0.515152 0.738095
42 KH3 0.514286 0.851351
43 A2D 0.511628 0.75
44 A3N 0.511628 0.814286
45 ABM 0.511628 0.75
46 A5A 0.510638 0.682353
47 5CA 0.510417 0.697674
48 SRA 0.505882 0.730769
49 S4M 0.505747 0.792208
50 AN2 0.505618 0.74026
51 A7D 0.505618 0.882353
52 A3S 0.505618 0.895522
53 GAP 0.505376 0.776316
54 LSS 0.5 0.681818
55 VMS 0.5 0.666667
56 DSH 0.5 0.871429
57 AP2 0.5 0.766234
58 LAD 0.5 0.818182
59 ADX 0.5 0.678571
60 BA3 0.5 0.75
61 M33 0.5 0.74026
62 A12 0.5 0.766234
63 KAA 0.5 0.712644
64 54H 0.5 0.666667
65 Y3J 0.5 0.80303
66 SXZ 0.49505 0.875
67 ME8 0.49505 0.775
68 AHX 0.494949 0.759494
69 TSB 0.494845 0.674419
70 53H 0.494845 0.659091
71 G5A 0.494624 0.697674
72 50T 0.494505 0.74026
73 AP5 0.494382 0.75
74 5AS 0.494382 0.640449
75 ADP 0.494382 0.75
76 B4P 0.494382 0.75
77 8QN 0.489796 0.786667
78 GEK 0.489796 0.913043
79 5AD 0.486842 0.828125
80 PAJ 0.484848 0.728395
81 52H 0.484536 0.659091
82 AU1 0.483516 0.730769
83 ADP MG 0.483516 0.74026
84 MAO 0.483146 0.782051
85 NEC 0.482759 0.797101
86 A3G 0.482759 0.882353
87 3AM 0.482353 0.733333
88 YAP 0.480769 0.802632
89 7D7 0.480519 0.794118
90 TXA 0.480392 0.766234
91 NB8 0.480392 0.782051
92 NVA LMS 0.48 0.681818
93 DAL AMP 0.479592 0.786667
94 ATF 0.479167 0.721519
95 ATP 0.478261 0.75
96 BEF ADP 0.478261 0.721519
97 ACP 0.478261 0.753247
98 ADP BEF 0.478261 0.721519
99 A3T 0.478261 0.852941
100 7MD 0.476636 0.775
101 XAH 0.47619 0.775
102 YSA 0.47619 0.697674
103 PRX 0.473118 0.753247
104 APR 0.473118 0.773333
105 AR6 0.473118 0.773333
106 AQP 0.473118 0.75
107 APC 0.473118 0.766234
108 5FA 0.473118 0.75
109 WAQ 0.470588 0.815789
110 4AD 0.47 0.802632
111 NSS 0.47 0.697674
112 AD9 0.468085 0.730769
113 RBY 0.468085 0.789474
114 AGS 0.468085 0.7125
115 SAP 0.468085 0.7125
116 ADV 0.468085 0.789474
117 ADP PO3 0.468085 0.77027
118 A5D 0.468085 0.84058
119 MHZ 0.467391 0.782051
120 FA5 0.466667 0.813333
121 PTJ 0.466019 0.7375
122 00A 0.465347 0.746835
123 D3Y 0.464646 0.869565
124 ATP MG 0.463158 0.74026
125 VRT 0.463158 0.871429
126 LEU LMS 0.460784 0.662921
127 OOB 0.46 0.786667
128 S8M 0.46 0.859155
129 ADP VO4 0.459184 0.74026
130 VO4 ADP 0.459184 0.74026
131 ACQ 0.458333 0.753247
132 TAT 0.458333 0.721519
133 ANP 0.458333 0.730769
134 AAT 0.453608 0.847222
135 2AM 0.453488 0.723684
136 FYA 0.451923 0.786667
137 YLC 0.451327 0.797468
138 DLL 0.45098 0.786667
139 A3P 0.450549 0.746667
140 YLP 0.45045 0.777778
141 A22 0.45 0.74026
142 ADP ALF 0.44898 0.7125
143 ALF ADP 0.44898 0.7125
144 TYR AMP 0.448598 0.789474
145 2VA 0.446809 0.828571
146 3UK 0.446602 0.776316
147 OAD 0.446602 0.776316
148 ANP MG 0.444444 0.7125
149 IOT 0.443478 0.768293
150 9SN 0.443396 0.7375
151 P5A 0.442308 0.704545
152 PR8 0.442308 0.807692
153 7D5 0.44186 0.714286
154 A1R 0.441176 0.769231
155 7C5 0.440367 0.797297
156 TT8 0.44 0.926471
157 YLA 0.439655 0.777778
158 YLB 0.438596 0.777778
159 1ZZ 0.438095 0.753086
160 3OD 0.438095 0.776316
161 BIS 0.438095 0.725
162 NVA 2AD 0.4375 0.816901
163 MAP 0.435644 0.7125
164 MYR AMP 0.433962 0.753086
165 NAI 0.433628 0.725
166 SO8 0.43299 0.816901
167 A6D 0.432692 0.74359
168 5SV 0.431373 0.7375
169 25A 0.431373 0.75
170 TYM 0.429825 0.813333
171 WSA 0.429825 0.705882
172 3NZ 0.428571 0.833333
173 ARG AMP 0.428571 0.765432
174 LAQ 0.428571 0.753086
175 ADQ 0.427184 0.753247
176 7MC 0.426087 0.756098
177 48N 0.424779 0.759494
178 LPA AMP 0.424779 0.753086
179 JB6 0.424528 0.746835
180 PPS 0.424242 0.658824
181 AYB 0.423729 0.768293
182 PAP 0.42268 0.736842
183 OVE 0.422222 0.696203
184 3AD 0.421687 0.863636
185 4YB 0.419643 0.72093
186 CMP 0.419355 0.753425
187 2BA 0.419355 0.743243
188 A2P 0.419355 0.733333
189 ADP BMA 0.419048 0.753247
190 4UV 0.418182 0.75641
191 ALF ADP 3PG 0.417391 0.75
192 LA8 ALF 3PG 0.417391 0.75
193 AHZ 0.415929 0.731707
194 QQX 0.41573 0.670886
195 A A 0.415094 0.75
196 AP0 0.413793 0.695122
197 ATP A A A 0.412844 0.76
198 RP1 0.411111 0.705128
199 QQY 0.411111 0.679487
200 SP1 0.411111 0.705128
201 ACK 0.411111 0.716216
202 AFH 0.410714 0.728395
203 4UU 0.410714 0.75641
204 DND 0.408696 0.766234
205 TXD 0.408696 0.725
206 NXX 0.408696 0.766234
207 7D3 0.408602 0.696203
208 25L 0.407407 0.74026
209 CC5 0.407407 0.876923
210 TAD 0.40708 0.75
211 AMP DBH 0.405405 0.753247
212 TXE 0.405172 0.725
213 OMR 0.405172 0.743902
214 AF3 ADP 3PG 0.405172 0.75
215 MTP 0.404762 0.72973
216 N0B 0.401575 0.777778
217 V3L 0.4 0.773333
218 YLY 0.4 0.768293
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2YX1; Ligand: SFG; Similar sites found: 263
This union binding pocket(no: 1) in the query (biounit: 2yx1.bio3) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3LKZ SFG 0.000003209 0.5086 0.934579
2 1XSE NDP 0.02169 0.41328 1.01695
3 1IM8 SAI 0.0000004513 0.52701 1.63934
4 2AOT SAH 0.0006265 0.44381 1.71233
5 3UCL FAD 0.002117 0.48227 1.78571
6 3UCL CYH 0.002117 0.48227 1.78571
7 3UCL NAP 0.002311 0.48227 1.78571
8 5KOK SAH 0.00002311 0.4755 1.78571
9 2WA2 SAM 0.000002799 0.56416 1.81159
10 4PNE SAH 0.000167 0.42514 1.98676
11 1N2X SAM 0.0000006081 0.50754 1.99336
12 1D4D FAD 0.001086 0.48135 2.08333
13 4MIG G3F 0.002073 0.4719 2.08333
14 2CDU FAD 0.001667 0.46445 2.08333
15 5UAO FAD 0.006722 0.43674 2.08333
16 2CDU ADP 0.005132 0.41526 2.08333
17 4J1Q NDP 0.01274 0.4115 2.08333
18 1KPH SAH 0.0003875 0.41669 2.09059
19 1KPG SAH 0.0003514 0.41649 2.09059
20 4TQG NDP 0.001091 0.46412 2.16718
21 3VC1 SAH 0.00009994 0.43845 2.24359
22 5BW4 SAM 0.0000183 0.52696 2.24719
23 1YXM ADE 0.01232 0.41698 2.31023
24 1PS9 FAD 0.0005924 0.49241 2.38095
25 4C3Y FAD 0.005621 0.4436 2.38095
26 4C3Y ANB 0.007435 0.44202 2.38095
27 2Y6Q FAD 0.004945 0.43651 2.38095
28 2Y6Q I7T 0.009547 0.43651 2.38095
29 3EVF SAH 0.000003158 0.40555 2.52708
30 4UP3 FAD 0.006868 0.43828 2.54777
31 2O07 MTA 0.0001125 0.4057 2.63158
32 2A14 SAH 0.001878 0.44311 2.6616
33 1U2Z SAH 0.000006013 0.5619 2.67857
34 3ICS FAD 0.0006405 0.4873 2.67857
35 5MPT SAH 0.00004927 0.47161 2.67857
36 1FEC FAD 0.002217 0.46863 2.67857
37 1XDS SAM 0.0005837 0.45349 2.67857
38 2VVM FAD 0.003996 0.45001 2.67857
39 5FJN FAD 0.00564 0.44449 2.67857
40 5FJN BE2 0.00639 0.44449 2.67857
41 1FP1 SAH 0.004652 0.4436 2.67857
42 1QZZ SAM 0.001318 0.43756 2.67857
43 5AHO TLA 0.007663 0.43138 2.67857
44 3ICT ADP 0.01047 0.4008 2.67857
45 1Z3C SA8 0.000004215 0.58175 2.68456
46 5GM1 SAH 0.0002064 0.42468 2.6936
47 1J0X NAD 0.02842 0.40994 2.71084
48 3OID NDP 0.02359 0.4045 2.71318
49 3H8V ATP 0.001695 0.43937 2.73973
50 3OU2 SAH 0.0001248 0.41708 2.75229
51 1L1E SAH 0.0003225 0.42639 2.78746
52 4RL4 PPV 0.01427 0.41429 2.83019
53 3RIY NAD 0.007467 0.4253 2.9304
54 5MGZ SAH 0.00001896 0.47861 2.9661
55 5DNK SAH 0.00001924 0.50321 2.97619
56 4ONQ SFG 0.00002996 0.48037 2.97619
57 4CNK FAD 0.001422 0.47017 2.97619
58 4AZT SAM 0.0003441 0.44043 2.97619
59 1KYZ SAH 0.0009766 0.42841 2.97619
60 4UCI SAM 0.001386 0.40921 2.97619
61 5ULP KB1 0.000000641 0.49282 2.98507
62 1RJD SAM 0.001054 0.45291 2.99401
63 2WSB NAD 0.002399 0.46105 3.14961
64 5E8J SAH 0.00001704 0.52256 3.20513
65 5E9W SAH 0.00002079 0.51019 3.20513
66 1QFY NAP 0.01641 0.41547 3.24675
67 1QFY FAD 0.01641 0.41547 3.24675
68 5F8F SFG 0.00004071 0.49467 3.27381
69 1QO8 FAD 0.0005819 0.49389 3.27381
70 1GET NAP 0.00236 0.48179 3.27381
71 1GET FAD 0.002228 0.48179 3.27381
72 1ELI PYC 0.000976 0.47825 3.27381
73 4N49 SAM 0.0001173 0.4477 3.27381
74 3CIF NAD 0.01494 0.40684 3.27381
75 3CIF G3H 0.02618 0.40334 3.27381
76 2XYQ SAH 0.00002329 0.48788 3.27869
77 1EJ0 SAM 0.000003662 0.56171 3.33333
78 1BC5 SAH 0.0007449 0.46373 3.34572
79 5GWX SAR 0.00004951 0.42219 3.52113
80 5GWX SAM 0.00004951 0.42219 3.52113
81 1I1N SAH 0.000001139 0.4634 3.53982
82 3P2E SAH 0.0003384 0.42639 3.55556
83 5JJR SAH 0.000001946 0.52696 3.57143
84 3GDN HBX 0.00447 0.45658 3.57143
85 3GDN FAD 0.003236 0.45658 3.57143
86 1AE1 NAP 0.009291 0.42435 3.663
87 5E1M SAH 0.00001155 0.47897 3.73444
88 3O7W SAM 0.0004505 0.45855 3.7415
89 4BV6 FAD 0.001394 0.47385 3.86905
90 1ZMD NAI 0.000175 0.41412 3.86905
91 1Y8Q ATP 0.0002533 0.41286 3.86905
92 3CMC NAD 0.04103 0.41516 3.89222
93 4FC7 COA 0.01578 0.42202 3.97112
94 4FC7 NAP 0.01578 0.42202 3.97112
95 1KYQ NAD 0.0003398 0.44857 4.0146
96 3DXY SAM 0.00001277 0.53528 4.12844
97 4BLW SAH 0.000005509 0.4557 4.15225
98 4BLW AMP 0.00000598 0.41408 4.15225
99 3QOX SAH 0.00002968 0.52938 4.16667
100 3OBT SLB 0.01047 0.42545 4.16667
101 4FZV SAM 0.0000009573 0.51766 4.1841
102 3CH6 311 0.02766 0.42191 4.1958
103 3CH6 NAP 0.02766 0.42191 4.1958
104 2BOS GLA GAL GLC 0.01025 0.41589 4.41176
105 2BOS GLA GAL GLC NBU 0.0135 0.408 4.41176
106 5N5D SAM 0.00004133 0.51587 4.42478
107 1X87 NAD 0.0008872 0.40191 4.46429
108 5CUQ NSC 0.0000009061 0.61779 4.49438
109 3GU3 SAH 0.00001341 0.54177 4.57746
110 3OFK SAH 0.0002127 0.42673 4.62963
111 2VT3 ATP 0.01086 0.40007 4.65116
112 5FTW SAH 0.00003998 0.45962 4.6875
113 5ITV NAI 0.0005253 0.48234 4.70588
114 1DL5 SAH 0.000003528 0.45864 4.73186
115 1N4W FAD 0.0004592 0.50011 4.7619
116 3TKY SAH 0.0001946 0.4848 4.7619
117 2WPF FAD 0.004281 0.47962 4.7619
118 2WPF WPF 0.005378 0.47563 4.7619
119 4J36 1HR 0.001939 0.46871 4.7619
120 4J36 FAD 0.001454 0.46364 4.7619
121 1JNR FAD 0.01645 0.44014 4.7619
122 3Q9T FAY 0.01552 0.41769 4.7619
123 3G89 SAM 0.000004222 0.54984 4.81928
124 2PZM NAD 0.02986 0.40885 4.84848
125 2PZM UDP 0.02986 0.40885 4.84848
126 1LSS NAD 0.0001131 0.4402 5
127 3BXO SAM 0.00004446 0.50382 5.02092
128 1JG3 ADN 0.00002246 0.48518 5.10638
129 1WG8 SAM 0.0000005075 0.61476 5.26316
130 1R18 SAH 0.005027 0.4515 5.28634
131 4NEC SAH 0.00005054 0.49059 5.30303
132 1NW5 SAM 0.000001509 0.58223 5.32915
133 2FK8 SAM 0.0003611 0.42387 5.34591
134 1I9G SAM 0.000001398 0.58649 5.35714
135 4KRI SAH 0.000003597 0.49289 5.35714
136 2XVE FAD 0.002865 0.47262 5.35714
137 2EG5 SAH 0.0002332 0.47142 5.35714
138 5L95 AMP 0.0006391 0.42282 5.37634
139 2HNK SAH 0.0001053 0.44836 5.43933
140 3FRH SAH 0.0007247 0.46429 5.5336
141 4J7U NAP 0.01 0.43199 5.55556
142 4J7U YTZ 0.01 0.43199 5.55556
143 1TPY SAH 0.000363 0.41764 5.57491
144 3PT9 SAH 0.0000002565 0.55999 5.65476
145 1V59 NAD 0.000119 0.49057 5.65476
146 3M6W SAM 0.0002035 0.4648 5.65476
147 1UP7 NAD 0.01094 0.4119 5.65476
148 1Z6Z NAP 0.008216 0.4233 5.67376
149 2VDV SAM 0.000007639 0.53825 5.69106
150 1PR9 NAP 0.003164 0.44719 5.7377
151 2YY7 NAD 0.009068 0.42248 5.76923
152 2P41 SAH 0.0000005421 0.54724 5.90164
153 4C4A SAH 0.00000003738 0.65637 5.95238
154 3LCC SAH 0.00002236 0.52299 5.95745
155 3BGD SAH 0.000005964 0.46873 6.15385
156 3BGD PM6 0.00001814 0.42351 6.15385
157 3CGD FAD 0.005531 0.467 6.25
158 3CGD NAD 0.005531 0.467 6.25
159 3CGD COA 0.005531 0.467 6.25
160 2BZG SAH 0.000006085 0.55159 6.46552
161 5M58 SAH 0.00008826 0.50066 6.52174
162 3X0D SAH 0.00000009136 0.63846 6.54762
163 4KRG SAH 0.000004446 0.52306 6.54762
164 1XTP SAI 0.000003637 0.56185 6.69291
165 2B9W FAD 0.02553 0.42053 6.83962
166 5X62 SAH 0.00001783 0.49964 6.84524
167 2PT9 S4M 0.02706 0.41854 6.85358
168 2PT9 2MH 0.0407 0.41854 6.85358
169 5THQ NDP 0.01339 0.41303 6.98529
170 3FZG SAM 0.0007323 0.4403 7
171 2PX8 SAH 0.00005012 0.50956 7.0632
172 4DCM SAM 0.00000123 0.57729 7.14286
173 1ZGA SAH 0.01646 0.41435 7.14286
174 1Q0S SAH 0.0000006785 0.60882 7.33591
175 1NV8 MEQ 0.0000004947 0.47526 7.39437
176 1NV8 SAM 0.0000005491 0.46682 7.39437
177 3I53 SAH 0.0002539 0.48162 7.53012
178 3TLJ SAH 0.000004887 0.47533 7.7381
179 2ZIF SAM 0.0000004167 0.53998 7.74411
180 2ZFU SAH 0.00002681 0.52694 7.90698
181 5JGL SAM 0.0004671 0.44024 7.95848
182 5JE0 AZ8 0.00000078 0.44318 8.09717
183 5JE0 SAH 0.00000078 0.44318 8.09717
184 5KVA SAM 0.00007347 0.44579 8.27338
185 3C6K MTA 0.00007641 0.53027 8.33333
186 3C6K SPD 0.00007641 0.53027 8.33333
187 5BUK FAD 0.004307 0.45224 8.33333
188 3GCZ SAM 0.0000005181 0.54884 8.51064
189 4R6W SAH 0.000015 0.40565 8.52713
190 5K7U SAM 0.000405 0.43446 8.88889
191 5FA5 MTA 0.0000005994 0.57291 8.92857
192 4GQB 0XU 0.001946 0.50589 8.92857
193 3S1S SAH 0.000002391 0.48762 8.92857
194 4X60 SFG 0.00000001609 0.44643 8.92857
195 4X60 3XV 0.00000001749 0.44068 8.92857
196 3EGV SAH 0.0000009693 0.55163 9.05512
197 2NXE SAM 0.000001211 0.53575 9.05512
198 3MQ2 SAH 0.0008176 0.4298 9.17431
199 3Q9N COA 0.0179 0.40307 9.21986
200 3FUU ADN 0.00002775 0.47422 9.22509
201 1G60 SAM 0.0000006433 0.53412 9.23077
202 5IL1 SAM 0.0004527 0.43377 9.43396
203 1L7N ALF 0.02152 0.4039 9.47867
204 1G55 SAH 0.0000001723 0.55534 9.52381
205 4M38 SAH 0.0000001451 0.54896 9.52381
206 5M67 NAD 0.02047 0.4212 9.52381
207 5M67 3D1 0.0215 0.42012 9.52381
208 5M67 ADE 0.03229 0.41102 9.52381
209 4YMH SAH 0.00003888 0.46306 9.58333
210 4XUC SAM 0.00001235 0.56607 9.63303
211 4XUC 43G 0.00001235 0.56607 9.63303
212 4Y2H SAH 0.0000008312 0.63167 9.82143
213 4Y2H 49K 0.0000008394 0.63146 9.82143
214 1P1C SAH 0.0005851 0.46865 10.0503
215 1SQF SAM 0.000008548 0.50097 10.119
216 5F7J ADE 0.005964 0.42919 10.625
217 1S7G NAD 0.01055 0.41929 10.6719
218 1S7G APR 0.01475 0.41452 10.6719
219 4POO SAM 0.0000005768 0.61214 11
220 3NTD FAD 0.003311 0.45198 11.0119
221 2EJU SAH 0.000000006712 0.6256 11.3095
222 5DWQ SFG 0.0000006627 0.6093 11.3095
223 5DX0 SFG 0.000001078 0.60169 11.3095
224 5DX8 SFG 0.0000005525 0.50448 11.3095
225 5DXA SFG 0.0000006267 0.50301 11.3095
226 5DX1 SFG 0.0000009199 0.4807 11.3095
227 1F3L SAH 0.0000004784 0.51598 11.5265
228 4LWP SAH 0.0000004566 0.55211 11.6071
229 3QVP FAD 0.002995 0.45923 11.6071
230 3EVG SAH 0.0000002696 0.55831 11.6364
231 1QAN SAH 0.0000008613 0.50911 11.8852
232 2DPM SAM 0.00001092 0.47327 11.9718
233 5LOG SAH 0.00007001 0.46045 12.4464
234 3GDH SAH 0.00000004793 0.5273 12.4481
235 3DUW SAH 0.00004965 0.51219 12.5561
236 3A4T SFG 0.0000002366 0.52762 12.7737
237 5XVQ SAH 0.0007046 0.4029 13.0282
238 4QTU SAM 0.000002987 0.51058 14.0741
239 2E5V FAD 0.008449 0.43659 14.2857
240 3EGI ADP 0.0000007298 0.62127 14.5631
241 4KIB SAH 0.000001232 0.58042 14.5833
242 3C3Y SAH 0.00008855 0.50059 14.7679
243 1E6E FAD 0.0002775 0.50274 14.8438
244 4IWN GEK 0.000003426 0.4776 14.8472
245 1L3I SAH 0.000000128 0.50845 15.1042
246 5T67 JHZ 0.001255 0.48017 15.7738
247 5T67 SAH 0.0009908 0.48017 15.7738
248 3NDJ JHZ 0.001417 0.47846 15.7738
249 3NDJ SAH 0.001417 0.47846 15.7738
250 1ZQ9 SAM 0.0000577 0.47003 15.7895
251 3DMH SAM 0.00000003612 0.57045 16.0714
252 3DMH GMP 0.00000007792 0.50039 16.0714
253 3T7S SAM 0.00005149 0.47163 16.4179
254 2AG5 NAD 0.008754 0.42197 17.0732
255 2F5Z FAD 0.001225 0.47873 17.1875
256 4OBW SAM 0.00008472 0.4626 17.8988
257 5XLX SAH 0.004574 0.41955 18.0851
258 3H2B SAH 0.00001595 0.48249 18.2266
259 2JJQ SAH 0.0000006195 0.58735 18.4524
260 5E72 SAM 0.000001041 0.59509 19.9405
261 5FA8 SAM 0.0000002442 0.51788 20.4969
262 3GRU AMP 0.0001233 0.4293 23.7288
263 1WY7 SAH 0.0000003421 0.52169 25.1208
Pocket No.: 2; Query (leader) PDB : 2YX1; Ligand: SFG; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 2yx1.bio3) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 2YX1; Ligand: SFG; Similar sites found: 135
This union binding pocket(no: 3) in the query (biounit: 2yx1.bio2) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1SAY PYR 0.02241 0.40668 1.4881
2 4NTD FAD 0.002136 0.46141 1.78571
3 4USQ FAD 0.00177 0.46074 1.78571
4 3LXD FAD 0.008617 0.42821 1.78571
5 1XKQ NDP 0.01157 0.41968 1.78571
6 1DSS NAD 0.01904 0.40042 1.8018
7 3CTY FAD 0.001094 0.48219 1.88088
8 1MO9 KPC 0.002223 0.48922 2.08333
9 1MO9 FAD 0.002269 0.48818 2.08333
10 1BZL FAD 0.005669 0.47347 2.08333
11 1V5F FAD 0.006213 0.45716 2.08333
12 3L4S 3PG 0.01015 0.42248 2.08333
13 3L4S NAD 0.009601 0.42248 2.08333
14 1RZM E4P 0.008504 0.4208 2.08333
15 1TDF FAD 0.0132 0.42935 2.21519
16 1TDF NAP 0.0294 0.42508 2.21519
17 1XHC FAD 0.0008012 0.48009 2.38095
18 1KNR FAD 0.003041 0.45592 2.38095
19 2RAB FAD 0.003866 0.4546 2.38095
20 2RAB NAD 0.007353 0.4546 2.38095
21 4USR FAD 0.002755 0.45012 2.38095
22 3GMB FAD 0.004228 0.44225 2.38095
23 1H82 GZZ 0.0254 0.42385 2.38095
24 3T31 DCQ 0.02315 0.42341 2.38095
25 3T31 FAD 0.02181 0.42341 2.38095
26 1H82 FAD 0.02409 0.42251 2.38095
27 1SB8 NAD 0.02514 0.41586 2.38095
28 2Q28 ADP 0.000843 0.41265 2.38095
29 2YYY NAP 0.0159 0.40817 2.38095
30 1SB8 UD2 0.04836 0.40402 2.38095
31 3LCV SAM 0.002697 0.4375 2.4911
32 3ICR FAD 0.00067 0.48514 2.67857
33 3ICT FAD 0.001204 0.47259 2.67857
34 2RGO FAD 0.001588 0.46664 2.67857
35 1I8T FAD 0.002415 0.45986 2.67857
36 2C31 TZD 0.009409 0.45194 2.67857
37 2C31 ADP 0.009176 0.45194 2.67857
38 3UOY NAP 0.01244 0.4432 2.67857
39 3EYA FAD 0.009742 0.42559 2.67857
40 2PWY SAH 0.000006044 0.56179 2.71318
41 4NBW NAD 0.007539 0.42244 2.72374
42 2EFJ SAH 0.0002384 0.4761 2.97619
43 3MJE NDP 0.001218 0.46328 2.97619
44 2V6G NAP 0.001487 0.46049 2.97619
45 1H9A NAP 0.002616 0.45245 2.97619
46 2DKH FAD 0.002675 0.45074 2.97619
47 2DKH 3HB 0.003684 0.45074 2.97619
48 1KYZ FER 0.00253 0.44514 2.97619
49 1DJN ADP 0.00405 0.42921 2.97619
50 2IV2 MGD 0.009636 0.4269 2.97619
51 3NUG NAD 0.002261 0.45169 3.23887
52 3TKA SAM 0.000006092 0.55682 3.27381
53 2AQJ TRP 0.01586 0.43263 3.27381
54 2AQJ FAD 0.01633 0.43263 3.27381
55 3V1U NAD 0.01028 0.41318 3.27381
56 1CDO NAD 0.01442 0.40757 3.27381
57 1UAY ADN 0.002064 0.42878 3.30579
58 2DTX BMA 0.004754 0.44524 3.40909
59 3SQP FAD 0.009578 0.47849 3.57143
60 2Q1S NAI 0.005187 0.44725 3.57143
61 3SJ7 NDP 0.00988 0.41814 3.57143
62 1GR0 NAD 0.02606 0.40344 3.57143
63 3S5W FAD 0.0006651 0.47739 3.86905
64 1RSG FAD 0.002981 0.45837 3.86905
65 1YY5 FAD 0.004897 0.44943 3.86905
66 4A6D SAM 0.0001482 0.44459 3.86905
67 3U4C NDP 0.0002703 0.49318 3.91459
68 2JAH NDP 0.01059 0.41921 4.04858
69 1EDO NAP 0.009017 0.42381 4.09836
70 1A27 NAP 0.01787 0.40695 4.15225
71 2V3A FAD 0.00135 0.47127 4.16667
72 2OBF F83 0.009953 0.4321 4.49827
73 3F8D FAD 0.04939 0.41245 4.64396
74 1XHL NDP 0.00763 0.42734 4.7138
75 1RYI FAD 0.00286 0.45828 4.7619
76 1KOL NAD 0.01636 0.41553 4.7619
77 1R6D DAU 0.03628 0.41054 4.7619
78 1R6D NAD 0.03739 0.41054 4.7619
79 2HMT NAI 0.0002917 0.48087 4.86111
80 1YC5 NCA 0.008809 0.4192 4.87805
81 4BUZ NAD 0.01214 0.41251 4.87805
82 4BUZ OAD 0.01454 0.41251 4.87805
83 4BUZ OCZ 0.01454 0.41251 4.87805
84 1G0N NDP 0.008297 0.4322 4.947
85 1G0N PHH 0.0117 0.42765 4.947
86 4FWE FAD 0.009567 0.43387 5.05952
87 4BJZ P3A 0.03209 0.42304 5.05952
88 2XVF FAD 0.001091 0.47469 5.35714
89 3LST SAH 0.0003341 0.46439 5.35714
90 2C7G ODP 0.008036 0.44582 5.35714
91 2C7G FAD 0.008301 0.44582 5.35714
92 1V59 FAD 0.0007478 0.49151 5.65476
93 2YVF FAD 0.005286 0.45881 5.65476
94 2YVF NAD 0.005448 0.45881 5.65476
95 2WK1 SAH 0.008805 0.41005 5.67376
96 3LAD FAD 0.001657 0.47114 5.95238
97 3O03 NAP 0.005282 0.42841 6.18557
98 4PIO SAH 0.0001591 0.51186 6.19195
99 4PIO AVI 0.0001506 0.51158 6.19195
100 1BXK NAD 0.006775 0.42603 6.25
101 1NM5 NAD 0.0282 0.41623 6.40394
102 1NM5 NAP 0.02732 0.41623 6.40394
103 2BGM NAJ 0.004328 0.43253 6.47482
104 3MB5 SAM 0.00001871 0.45993 6.66667
105 1UXG NAD 0.02587 0.40758 6.79612
106 2NVK FAD 0.005187 0.44535 6.84524
107 3AD8 NAD 0.00005852 0.53307 7.07071
108 2GAG NAD 0.00007951 0.53079 7.07071
109 3AD8 FAD 0.009535 0.44867 7.07071
110 2GAG FAD 0.009127 0.43665 7.07071
111 2GAG FOA 0.01586 0.42449 7.07071
112 1KEW NAD 0.02218 0.4209 7.14286
113 1PNO NAP 0.01184 0.41563 7.22222
114 3SSO SAH 0.0001441 0.43935 8.03571
115 3GEG NAD 0.0003095 0.48873 8.09717
116 3QWI CUE 0.02149 0.41437 8.14815
117 3QWI NAP 0.01408 0.41437 8.14815
118 1REO FAD 0.004728 0.44536 8.33333
119 2AE2 NAP 0.01351 0.4236 8.84615
120 4D04 NAP 0.002738 0.47506 8.92857
121 4M37 SAH 0.0000001632 0.62682 9.52381
122 4AT0 FAD 0.01426 0.42846 9.82143
123 1O97 AMP 0.002085 0.47676 9.84848
124 3HVJ 705 0.00002249 0.55783 9.95475
125 2GDZ NAD 0.001886 0.45413 10.1124
126 3NT6 FAD 0.008905 0.43067 10.7143
127 4II2 ATP 0.002554 0.43506 10.8434
128 1FL2 FAD 0.03764 0.40031 10.9677
129 3RKR NAP 0.003372 0.40927 11.0687
130 1R37 NAD 0.01372 0.41719 11.5274
131 1YB5 NAP 0.02336 0.40579 12.8205
132 4EUE NAI 0.0002021 0.5039 13.0952
133 1ZEM NAD 0.0005597 0.47482 14.1221
134 1LVL NAD 0.0004074 0.42384 16.6667
135 3CBG SAH 0.0000427 0.485 19.8276
Pocket No.: 4; Query (leader) PDB : 2YX1; Ligand: SFG; Similar sites found: 4
This union binding pocket(no: 4) in the query (biounit: 2yx1.bio1) has 18 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1CF2 NAP 0.01778 0.40322 1.78571
2 1ORR NAD 0.02706 0.40156 1.78571
3 2RGH FAD 0.03687 0.40164 2.67857
4 1U3U BNF 0.03314 0.40571 7.7381
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