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Receptor
PDB id Resolution Class Description Source Keywords
2ZHL 1.75 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF HUMAN GALECTIN-9 N-TERMINAL CRD IN COMP N-ACETYLLACTOSAMINE DIMER (CRYSTAL 2) HOMO SAPIENS BETA SANDWICH CARBOHYDRATE BINDING PROTEIN GALECTIN SUGARPROTEIN
Ref.: STRUCTURAL ANALYSIS OF THE RECOGNITION MECHANISM OF POLY-N-ACETYLLACTOSAMINE BY THE HUMAN GALECTIN-9 N-CARBOHYDRATE RECOGNITION DOMAIN. GLYCOBIOLOGY V. 19 112 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
NAG GAL GAL NAG A:1491;
B:1495;
C:1499;
D:1503;
Valid;
Valid;
Valid;
Valid;
none;
none;
none;
none;
Kd = 3 uM
748.685 n/a O=C(N...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ZHL 1.75 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF HUMAN GALECTIN-9 N-TERMINAL CRD IN COMP N-ACETYLLACTOSAMINE DIMER (CRYSTAL 2) HOMO SAPIENS BETA SANDWICH CARBOHYDRATE BINDING PROTEIN GALECTIN SUGARPROTEIN
Ref.: STRUCTURAL ANALYSIS OF THE RECOGNITION MECHANISM OF POLY-N-ACETYLLACTOSAMINE BY THE HUMAN GALECTIN-9 N-CARBOHYDRATE RECOGNITION DOMAIN. GLYCOBIOLOGY V. 19 112 2009
Members (7)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 510 families.
1 2EAL - GAL NGA A2G n/a n/a
2 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
3 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
4 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
5 2ZHM - NAG GAL GAL NAG GAL n/a n/a
6 2EAK - LBT C12 H22 O11 C([C@@H]1[....
7 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
70% Homology Family (10)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 391 families.
1 2D6N - GAL NAG n/a n/a
2 2D6M - LBT C12 H22 O11 C([C@@H]1[....
3 2D6O - NAG GAL GAL NAG n/a n/a
4 2EAL - GAL NGA A2G n/a n/a
5 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
6 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
7 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
8 2ZHM - NAG GAL GAL NAG GAL n/a n/a
9 2EAK - LBT C12 H22 O11 C([C@@H]1[....
10 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
50% Homology Family (109)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 298 families.
1 5NF9 Kd = 4.7 uM 8VW C22 H32 N2 O12 CC(=O)N[C@....
2 5E8A Kd = 0.034 uM 5KS C28 H30 F2 N6 O8 S c1cc(ccc1c....
3 1A3K - GAL NAG n/a n/a
4 3T1M Kd = 0.91 mM DQT C23 H27 N O7 Cc1ccc(cc1....
5 4LBL Kd = 11 uM BGC SIA GAL n/a n/a
6 2NMN Kd = 260 uM GAL BGC n/a n/a
7 4R9B - LAT C12 H22 O11 C([C@@H]1[....
8 2NN8 Kd = 260 uM LAT C12 H22 O11 C([C@@H]1[....
9 4JC1 Kd = 50 uM TDG C12 H22 O10 S C([C@@H]1[....
10 4R9A - LAT C12 H22 O11 C([C@@H]1[....
11 5EXO - 5SY C19 H22 O9 CC(=O)O[C@....
12 5ODY Kd = 7.5 nM 9SK C30 H28 F5 N3 O11 S c1cc(c(c2c....
13 5E88 Kd = 0.065 uM 5KT C24 H28 N6 O8 S3 c1cscc1c2c....
14 4R9D - LAT C12 H22 O11 C([C@@H]1[....
15 1KJL Kd = 67 uM GAL NAG n/a n/a
16 3T1L Kd = 0.55 mM MQT C17 H22 O8 Cc1ccc(cc1....
17 2XG3 Kd = 18.2 uM UNU GAL NAG n/a n/a
18 4LBJ Kd = 0.39 uM GAL NAG GAL BGC n/a n/a
19 4R9C - LAT C12 H22 O11 C([C@@H]1[....
20 3ZSJ Kd = 231 uM LAT C12 H22 O11 C([C@@H]1[....
21 4LBM Kd = 0.97 uM BGC GAL NAG GAL n/a n/a
22 1KJR Kd = 0.88 uM BEK GAL NAG n/a n/a
23 6EOL Kd = 0.037 uM BKH C20 H16 Cl2 F3 N3 O4 S c1cc(c(cc1....
24 6G0V Kd = 166 uM EGZ C18 H25 N O13 S C1[C@H](NC....
25 3AYE - LAT C12 H22 O11 C([C@@H]1[....
26 6EOG Kd = 1.6 uM BKK C20 H17 Cl F3 N3 O4 S c1cc(cc(c1....
27 5E89 Kd = 0.014 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
28 4LBO Kd = 1.7 uM BGC GAL SIA n/a n/a
29 2NMO Kd = 260 uM GAL BGC n/a n/a
30 3AYC Kd = 57 uM GAL NGA GAL BGC SIA n/a n/a
31 4JCK Kd = 4.3 mM 1LL C12 H22 O10 S C([C@@H]1[....
32 5NFA Kd = 5.6 uM 8VQ C24 H36 N2 O12 CC(=O)N[C@....
33 4LBK Kd = 0.32 uM GAL NAG GAL BGC n/a n/a
34 5OAX Kd = 12 nM 9Q5 C30 H30 F3 N3 O11 S c1cc(cc(c1....
35 4RL7 - LAT C12 H22 O11 C([C@@H]1[....
36 3AYD Kd = 65 uM NPO A2G GAL n/a n/a
37 4LBN Kd = 0.65 uM GLC GAL NAG GAL n/a n/a
38 1G86 - NEQ C6 H7 N O2 CCN1C(=O)C....
39 1QKQ - MAN C6 H12 O6 C([C@@H]1[....
40 1HDK - PMB C6 H5 Hg O3 S c1cc(ccc1S....
41 2D6N - GAL NAG n/a n/a
42 2D6M - LBT C12 H22 O11 C([C@@H]1[....
43 2D6O - NAG GAL GAL NAG n/a n/a
44 4XBN Kd = 93 uM GAL NAG n/a n/a
45 5H9R Kd = 0.84 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
46 5H9P Kd = 0.068 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
47 5DG2 - GAL GLC n/a n/a
48 5EWS - GAL BGC n/a n/a
49 5NM1 - LBT C12 H22 O11 C([C@@H]1[....
50 5NLD - LBT C12 H22 O11 C([C@@H]1[....
51 5NMJ - LBT C12 H22 O11 C([C@@H]1[....
52 5NLH - LBT C12 H22 O11 C([C@@H]1[....
53 5NLE - LBT C12 H22 O11 C([C@@H]1[....
54 4XBL Kd = 340 uM GAL NAG n/a n/a
55 4Y24 Kd = 0.22 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
56 3T2T - MQT C17 H22 O8 Cc1ccc(cc1....
57 3OY8 Kd = 220 uM GAL GCO n/a n/a
58 2EAL - GAL NGA A2G n/a n/a
59 2ZHL Kd = 3 uM NAG GAL GAL NAG n/a n/a
60 2ZHK Kd = 3 uM NAG GAL GAL NAG n/a n/a
61 2ZHN - NAG GAL NAG GAL GAL NAG n/a n/a
62 2ZHM - NAG GAL GAL NAG GAL n/a n/a
63 2EAK - LBT C12 H22 O11 C([C@@H]1[....
64 3WLU - LSE C18 H36 O10 Se Si C[Si](C)(C....
65 5H9S Kd = 87 uM TGZ C20 H26 F N3 O9 S c1cc(cc(c1....
66 5H9Q Kd = 38 uM TD2 C28 H30 F2 N6 O8 S c1cc(cc(c1....
67 4XBQ Kd = 270 uM GAL NAG n/a n/a
68 6A62 - LAT C12 H22 O11 C([C@@H]1[....
69 6A64 - LAT C12 H22 O11 C([C@@H]1[....
70 6A63 - LAT C12 H22 O11 C([C@@H]1[....
71 5T7S Kd = 3.1 uM LBT C12 H22 O11 C([C@@H]1[....
72 4BMB Ka = 13000 M^-1 LAT C12 H22 O11 C([C@@H]1[....
73 5T7I Kd = 0.33 uM LAT NAG GAL n/a n/a
74 3VKO - SIA GAL NAG n/a n/a
75 4BME Ka = 13000 M^-1 LBT C12 H22 O11 C([C@@H]1[....
76 5T7T Kd = 2.1 uM GAL NAG n/a n/a
77 3I8T Kd = 600 uM LBT C12 H22 O11 C([C@@H]1[....
78 3WV6 - GAL BGC n/a n/a
79 3NV2 - GAL NDG n/a n/a
80 3NV4 - SIA GAL BGC n/a n/a
81 3NV3 - GAL NAG MAN n/a n/a
82 3WUD Kd = 41 uM GLC GAL n/a n/a
83 3GAL - 1GN C6 H13 N O5 C([C@@H]1[....
84 4UW6 - VV7 C69 H73 N20 O39 [H]1c2c(cc....
85 2GAL - GAL C6 H12 O6 C([C@@H]1[....
86 4GAL - GAL BGC n/a n/a
87 4UW3 - 50G C31 H50 N10 O18 c1c(nnn1[C....
88 4UW4 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
89 3ZXE Kd = 450 uM PGZ C22 H28 N O8 P S Cc1ccc(cc1....
90 5GAL - NAG GAL n/a n/a
91 4UW5 - 4S0 C49 H80 N10 O33 c1c(nnn1[C....
92 1A78 - TDG C12 H22 O10 S C([C@@H]1[....
93 5DUW Kd = 510 uM 5GO C12 H22 O14 S C([C@@H]1[....
94 5DUV Kd = 1300 uM LAT C12 H22 O11 C([C@@H]1[....
95 5DUX Kd = 380 uM LAT FUC n/a n/a
96 4WVV - LBT C12 H22 O11 C([C@@H]1[....
97 4WVW - SLT C23 H39 N O19 CC(=O)N[C@....
98 4YLZ Kd = 270 uM LAT NAG GAL n/a n/a
99 5CBL - LAT C12 H22 O11 C([C@@H]1[....
100 4YM0 Kd = 510 uM LAT NAG GAL n/a n/a
101 4YM2 Kd = 1400 uM SGA BGC n/a n/a
102 4YM3 Kd = 1900 uM LAT C12 H22 O11 C([C@@H]1[....
103 4YM1 Kd = 580 uM LAT FUC n/a n/a
104 1IS4 - LAT C12 H22 O11 C([C@@H]1[....
105 1WLD - GAL BGC n/a n/a
106 6FOF - LAT C12 H22 O11 C([C@@H]1[....
107 5NFB Kd = 0.77 uM 8VT C30 H40 N2 O13 CC(=O)N[C@....
108 5NF7 Kd = 37.5 uM 8VZ C16 H28 N2 O11 CC(=O)N[C@....
109 1SLA - NAG MAN GAL BMA NAG MAN NAG GAL n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: NAG GAL GAL NAG; Similar ligands found: 251
No: Ligand ECFP6 Tc MDL keys Tc
1 NAG GAL GAL NAG 1 1
2 GAL NAG GAL NAG GAL NAG 1 0.979592
3 GLA GAL NAG 0.852941 0.9375
4 MAN BMA NAG 0.852941 0.9375
5 GLC GAL NAG GAL 0.824324 0.9375
6 LAT NAG GAL 0.824324 0.9375
7 NAG GAL NAG 0.819444 1
8 NAG GAL GAL NAG GAL 0.810811 1
9 NAG NAG BMA MAN MAN 0.771084 1
10 GAL NAG GAL BGC 0.746835 0.9
11 NDG GAL 0.746269 0.9375
12 GAL NDG 0.746269 0.9375
13 NLC 0.746269 0.9375
14 NAG MAN MAN MAN NAG GAL NAG GAL 0.719101 0.979592
15 MAN BMA NAG NAG MAN NAG GAL GAL 0.719101 0.979592
16 NAG NAG NAG NAG NAG NAG NAG NAG 0.69863 0.979592
17 NDG NAG NAG 0.69863 0.979592
18 NAG NAG NDG NAG 0.69863 0.979592
19 NDG NAG NAG NAG 0.69863 0.979592
20 NAG NAG NAG NDG 0.69863 0.979592
21 NAG NAG NAG NAG NAG 0.69863 0.979592
22 NAG NAG NAG NAG NAG NAG 0.69863 0.979592
23 NDG NAG NAG NDG 0.69863 0.979592
24 NAG NAG NAG NAG NDG 0.69863 0.979592
25 NAG NAG NDG 0.69863 0.979592
26 CTO 0.69863 0.979592
27 NAG NAG BMA MAN 0.690476 0.923077
28 FUC BGC GAL NAG GAL 0.689655 0.958333
29 GAL NAG MAN 0.684211 0.9375
30 NAG MAN BMA NDG MAN NAG GAL 0.680851 0.979592
31 NAG NAG BMA MAN MAN NAG GAL NAG 0.673684 0.979592
32 NAG NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.659794 1
33 NGA GLA GAL BGC 0.658537 0.9375
34 NAG GAL BGC 0.658228 0.9375
35 TCG 0.65 0.827586
36 CBS 0.643836 1
37 NAG GDL 0.643836 1
38 CBS CBS 0.643836 1
39 NDG NAG 0.643836 1
40 GAL NAG GAL GLC 0.641975 0.9375
41 BGC GAL NAG GAL 0.641975 0.9375
42 NAG BMA MAN MAN MAN MAN 0.636364 0.9375
43 GAL NGA GLA BGC GAL 0.630952 0.9375
44 GAL NAG GAL 0.62963 0.9
45 NAG BMA NAG MAN MAN NAG NAG 0.621053 0.979592
46 M5G 0.606061 1
47 NAG NAG BMA 0.60241 0.923077
48 NAG NDG BMA 0.60241 0.923077
49 BMA NAG MAN MAN MAN MAN MAN MAN MAN 0.595745 0.9375
50 FUC C4W NAG BMA MAN 0.575758 0.923077
51 G6S NAG 0.573171 0.71875
52 GAL BGC NAG GAL 0.571429 0.9375
53 NAG FUC 0.565789 0.916667
54 A2G GAL NAG FUC 0.554348 0.979592
55 FUC GAL NAG A2G 0.554348 0.979592
56 GLA GAL GAL 0.546667 0.6875
57 8VZ 0.539474 0.979592
58 BGC BGC BGC BGC BGC BGC BGC BGC 0.538462 0.6875
59 GAL GLC NAG GAL FUC 0.536842 0.958333
60 GLC NAG GAL GAL FUC 0.536842 0.958333
61 FUC GAL NAG GAL BGC 0.536842 0.958333
62 GAL NAG FUC 0.535714 0.958333
63 DR2 0.535714 0.958333
64 NAG GAL FUC 0.535714 0.958333
65 FUC GAL NDG 0.535714 0.958333
66 FUC GAL NAG 0.535714 0.958333
67 NDG GAL FUC 0.535714 0.958333
68 FUL GAL NAG 0.535714 0.958333
69 NAG MAN BMA MAN NAG GAL 0.535354 1
70 NAG NAG BMA BMA 0.533333 0.888889
71 FUC BGC GAL NAG 0.532609 0.958333
72 GLC GAL NAG GAL FUC FUC 0.530612 0.938776
73 BGC GAL NAG GAL FUC FUC 0.530612 0.938776
74 NGA GAL BGC 0.53012 0.9375
75 GLA GAL NAG FUC GAL GLC 0.525253 0.958333
76 NAG NAG BMA MAN MAN MAN MAN 0.523364 0.923077
77 A2G GAL 0.519481 0.9375
78 GAL A2G 0.519481 0.9375
79 GAL NGA 0.519481 0.9375
80 NAG MBG 0.518987 0.938776
81 A2G GAL NAG FUC GAL GLC 0.514563 0.979592
82 GLC GAL NAG GAL FUC A2G 0.514563 0.979592
83 SIA GAL NAG GAL BGC 0.513043 0.90566
84 SIA GAL NAG GAL GLC 0.513043 0.90566
85 BGC GAL NAG SIA GAL 0.513043 0.90566
86 GAL NAG 0.506329 0.9375
87 NAG GAL 0.506329 0.9375
88 NAG GCU NAG GCD 0.5 0.888889
89 FUC C4W NAG BMA 0.5 0.923077
90 NAG NAG FUL BMA MAN MAN NAG GAL 0.495575 0.90566
91 UNU GAL NAG 0.494505 0.94
92 SN5 SN5 0.493827 0.826923
93 BGC BGC BGC GLC BGC BGC 0.493333 0.6875
94 GLC BGC BGC BGC BGC BGC BGC 0.493333 0.6875
95 GAL NAG GAL FUC 0.48913 0.958333
96 GLA NAG GAL FUC 0.48913 0.958333
97 NAG NAG NAG NAG 0.488636 0.90566
98 NAG NAG NAG 0.488636 0.90566
99 ACY 1GN GAL 1GN BGC ACY GAL BGC 0.484536 1
100 1GN ACY GAL ACY 1GN BGC GAL BGC 0.484536 1
101 GAL NGA A2G 0.482353 1
102 GAL MGC 0.481013 0.938776
103 4U2 0.475728 0.941176
104 GAL NDG FUC 0.471264 0.958333
105 FUC NDG GAL 0.471264 0.958333
106 HS2 0.471264 0.862745
107 NAG SIA GAL 0.466667 0.923077
108 FUC C4W NAG BMA MAN MAN NAG 0.466102 0.923077
109 NAG MAN MMA 0.465909 0.938776
110 NAG NAG BMA MAN MAN NAG NAG 0.463636 0.90566
111 NAG A2G 0.463415 1
112 NAG NGA 0.463415 1
113 NAG BMA 0.463415 0.846154
114 GCS GCS NAG 0.462366 0.901961
115 NAG A2G GAL 0.461538 1
116 MBG A2G 0.457831 0.938776
117 A2G MBG 0.457831 0.938776
118 MAN MAN MAN GLC 0.457831 0.6875
119 GAL NAG SIA GAL 0.45614 0.90566
120 NAG MAN BMA 0.454545 0.9375
121 M13 0.453333 0.693878
122 GAL MBG 0.453333 0.693878
123 MDM 0.453333 0.693878
124 NAG NAG BMA MAN NAG 0.45283 0.90566
125 Z4S NAG NAG 0.451613 0.90566
126 NOJ NAG NAG NAG 0.451613 0.857143
127 NOJ NAG NAG 0.451613 0.872727
128 NAG GAL NGC 0.45045 0.886792
129 LAT 0.445946 0.6875
130 BGC GAL 0.445946 0.6875
131 CBI 0.445946 0.6875
132 GLC GAL 0.445946 0.6875
133 LBT 0.445946 0.6875
134 BMA GAL 0.445946 0.6875
135 MAB 0.445946 0.6875
136 GLA GLA 0.445946 0.6875
137 GAL BGC 0.445946 0.6875
138 BGC BMA 0.445946 0.6875
139 MAL 0.445946 0.6875
140 N9S 0.445946 0.6875
141 B2G 0.445946 0.6875
142 CBK 0.445946 0.6875
143 GLA GAL 0.445946 0.6875
144 A2G GAL BGC FUC 0.444444 0.958333
145 NAG GAL SIA 0.444444 0.90566
146 4U1 0.444444 0.923077
147 BMA MAN BMA 0.441558 0.6875
148 MAN MAN BMA BMA BMA BMA 0.441558 0.6875
149 CE6 0.441558 0.6875
150 MTT 0.441558 0.6875
151 GLC BGC BGC BGC 0.441558 0.6875
152 BGC BGC BGC BGC BGC BGC BGC BGC BGC 0.441558 0.6875
153 BGC BGC BGC GLC 0.441558 0.6875
154 CTR 0.441558 0.6875
155 GLA GAL BGC 0.441558 0.6875
156 BMA BMA BMA 0.441558 0.6875
157 BGC GLC GLC 0.441558 0.6875
158 GLC GLC GLC GLC GLC 0.441558 0.6875
159 GLC BGC BGC BGC BGC 0.441558 0.6875
160 BGC GLC GLC GLC GLC GLC GLC 0.441558 0.6875
161 CEX 0.441558 0.6875
162 GLC GAL GAL 0.441558 0.6875
163 MAN BMA BMA 0.441558 0.6875
164 MLR 0.441558 0.6875
165 CE5 0.441558 0.6875
166 MAN BMA BMA BMA BMA 0.441558 0.6875
167 BGC BGC BGC BGC BGC 0.441558 0.6875
168 BMA BMA BMA BMA BMA 0.441558 0.6875
169 MT7 0.441558 0.6875
170 GLC BGC BGC BGC BGC BGC 0.441558 0.6875
171 U63 0.441558 0.634615
172 DXI 0.441558 0.6875
173 MAN BMA BMA BMA BMA BMA 0.441558 0.6875
174 BGC BGC BGC BGC BGC BGC 0.441558 0.6875
175 GLC BGC BGC 0.441558 0.6875
176 BGC BGC BGC 0.441558 0.6875
177 BGC BGC GLC 0.441558 0.6875
178 BGC GLC GLC GLC 0.441558 0.6875
179 GLA GAL GLC 0.441558 0.6875
180 BGC GLC GLC GLC GLC 0.441558 0.6875
181 GAL GAL GAL 0.441558 0.6875
182 CE8 0.441558 0.6875
183 GLC GLC BGC 0.441558 0.6875
184 BGC BGC BGC BGC 0.441558 0.6875
185 B4G 0.441558 0.6875
186 GLC GLC GLC GLC GLC GLC GLC GLC GLC 0.441558 0.6875
187 GLC BGC GLC 0.441558 0.6875
188 CEY 0.441558 0.6875
189 BMA BMA BMA BMA BMA BMA 0.441558 0.6875
190 CTT 0.441558 0.6875
191 CT3 0.441558 0.6875
192 KPM 0.438776 0.903846
193 NAG NAG NGT 0.4375 0.813559
194 BEK GAL NAG 0.435644 0.842105
195 FUC GAL A2G 0.428571 0.958333
196 A2G GAL FUC 0.428571 0.958333
197 FUC GLA A2G 0.428571 0.958333
198 NGA GAL FUC 0.428571 0.958333
199 A2G GLA FUC 0.428571 0.958333
200 LB2 0.426667 0.6875
201 M3M 0.426667 0.6875
202 MAN GLC 0.426667 0.6875
203 NGR 0.426667 0.6875
204 DLD 0.425532 0.827586
205 FUC C4W NAG BMA MAN MAN NAG NAG 0.425 0.923077
206 FUC GAL NAG GAL FUC 0.424242 0.938776
207 NAG AMU NAG AMV 0.424242 0.941176
208 NAG BMA MAN MAN MAN MAN MAN MAN MAN 0.422018 0.865385
209 NAG GAL FUC FUC A2G 0.421569 0.979592
210 FUC GAL NAG A2G FUC 0.421569 0.979592
211 ASN NAG NAG BMA MAN MAN NAG NAG 0.420168 0.872727
212 GAL A2G MBN 0.419355 0.9
213 NGA GAL 0.418605 0.88
214 GLC GLC XYP 0.418605 0.6875
215 GLA EGA 0.417722 0.693878
216 ASG 0.417722 0.65625
217 A2G SER GAL 0.417582 0.903846
218 GAL TNR 0.417582 0.903846
219 NGA SER GAL 0.417582 0.903846
220 GAL SER A2G 0.417582 0.903846
221 8VW 0.415842 0.90566
222 MMA MAN 0.415584 0.693878
223 DR5 0.415584 0.693878
224 NAG AMU 0.414894 0.96
225 NAG MUB 0.414894 0.96
226 GAL LOG 0.413793 0.793103
227 LAT GLA 0.413333 0.6875
228 AO3 0.411765 0.738462
229 NAA NAA AMI 0.411765 0.738462
230 UMG 0.409524 0.857143
231 NAG NAG 0.409091 0.903846
232 NAG NDG 0.409091 0.903846
233 GAL A2G THR 0.408602 0.941176
234 6Y2 0.408163 0.75
235 MAG FUC GAL 0.406593 0.92
236 BGC FUC GAL FUC A2G 0.405941 0.938776
237 NAG BDP NAG BDP NAG BDP NAG 0.405941 0.96
238 GLC FUC GAL FUC A2G 0.405941 0.938776
239 FUC GAL NAG FUC 0.404255 0.938776
240 FUC NDG GAL FUC 0.404255 0.938776
241 FUC GAL NDG FUC 0.404255 0.938776
242 GAL NDG FUC FUC 0.404255 0.938776
243 GAL NAG FUC FUC 0.404255 0.938776
244 NAG MAN MAN 0.404255 0.9375
245 BCW 0.404255 0.938776
246 BDZ 0.404255 0.938776
247 FUC NAG GAL FUC 0.404255 0.938776
248 NAG MAN MAN MAN NAG 0.40404 1
249 WZ5 0.403846 0.938776
250 NDG BDP BDP NPO NDG 0.401786 0.75
251 FUC C4W NAG BMA MAN NAG 0.401709 0.923077
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2ZHL; Ligand: NAG GAL GAL NAG; Similar sites found with APoc: 265
This union binding pocket(no: 1) in the query (biounit: 2zhl.bio4) has 17 residues
No: Leader PDB Ligand Sequence Similarity
1 5IXG OTP None
2 3EKK GS2 None
3 2QX0 PH2 None
4 3N0Y APC None
5 4ZSI GLP None
6 1QY1 PRZ None
7 2Y88 2ER None
8 4ZSI 4R1 None
9 5JFS 6K0 None
10 5N2F 8HW None
11 2HK5 1BM None
12 2P7Q GG6 None
13 5HV0 AKG None
14 2BOS GLA GAL None
15 2BOS GLA GAL GLC None
16 4IPH 1FJ None
17 3KFF ZBT None
18 3KFF XBT None
19 1CBK ROI None
20 3FW4 CAQ None
21 5NIU 8YZ None
22 4NS0 PIO None
23 3ZO7 K6H None
24 3E85 BSU 1.35135
25 3RGA LSB 1.35135
26 5JSP DQY 1.35135
27 5EPQ OLA 1.35135
28 3H5N ATP 1.35135
29 3I7V ATP 1.49254
30 3QRC SCR 2.02703
31 2A1L PCW 2.02703
32 4EE7 PIS 2.02703
33 2Y6O 1N1 2.02703
34 5KO1 6UY 2.02703
35 4RYV ZEA 2.02703
36 5TPV TYD 2.02703
37 2YG2 FLC 2.02703
38 1NYW DAU 2.02703
39 1IIU RTL 2.02703
40 2YG2 S1P 2.02703
41 5IXH OTP 2.02703
42 5MJA 7O3 2.02703
43 3W68 VIV 2.02703
44 4YGF AZM 2.02703
45 4TW7 37K 2.34375
46 4WN5 MVC 2.6087
47 3PP0 03Q 2.7027
48 3PQB VGP 2.7027
49 4MP8 MLI 2.7027
50 4MP8 NAD 2.7027
51 1TT8 PHB 2.7027
52 4MOB ADP 2.7027
53 6FE1 V14 2.7027
54 5A89 ADP 2.7027
55 4K55 H6P 3.22581
56 5DQ8 FLF 3.33333
57 5DRB 5FJ 3.37838
58 5EOB 5QQ 3.37838
59 4MNS 2AX 3.37838
60 4FHD 0TT 3.37838
61 4FHD EEM 3.37838
62 4NV7 COA 3.37838
63 2VFT SOR 3.37838
64 2XVD AS6 3.37838
65 4RFR RHN 3.37838
66 4U03 GTP 3.37838
67 4U03 TLL 3.37838
68 5KEW 6SB 3.47222
69 6GNO XDI 3.7037
70 5B09 4MX 3.84615
71 1KGI T4A 3.93701
72 3RJY GLC 4.05405
73 5HA0 LTD 4.05405
74 3LVW GSH 4.05405
75 4YMJ 4EJ 4.05405
76 1SMR PIV HIS PRO PHE HIS LPL TYR TYR SER 4.05405
77 2YNE YNE 4.05405
78 2YNE NHW 4.05405
79 4H2V AMP 4.05405
80 5EYK 5U5 4.05405
81 4ZU4 4TG 4.05405
82 4RF7 ARG 4.05405
83 3MF2 AMP 4.05405
84 4C2V YJA 4.05405
85 3FW9 SLX 4.05405
86 4H2X G5A 4.05405
87 4H2W 5GP 4.05405
88 4H2W AMP 4.05405
89 1ZB6 GST 4.72973
90 1ZB6 DIN 4.72973
91 5J75 6GQ 4.72973
92 5W1E PHB 4.72973
93 5XVG 8FX 4.72973
94 4Q0P 0MK 4.72973
95 1ELI PYC 4.72973
96 1ERB ETR 4.72973
97 2OFV 242 4.72973
98 3B1Q NOS 4.72973
99 5OX6 A1Z 4.72973
100 5O5Y GLC 4.72973
101 3W9R A8S 4.72973
102 3VQ2 LP4 LP5 MYR DAO 4.86111
103 5C3R AKG 4.95627
104 5C3R HMU 4.95627
105 1N5S ADL 5.35714
106 2AG4 OLA 5.40541
107 2AG4 LP3 5.40541
108 5VC5 96M 5.40541
109 2XK9 XK9 5.40541
110 1GP6 QUE 5.40541
111 2OVW CBI 5.40541
112 1I7E IBS 5.40541
113 3WDX BGC BGC GLC 5.40541
114 3ZXR P3S 5.40541
115 3ZXR IQ1 5.40541
116 4PFC 2QX 5.40541
117 4WOE ADP 5.40541
118 4KBA 1QM 5.40541
119 2CM4 RCL 5.40541
120 5WHU SIA GAL GLC 5.40541
121 2WA4 069 5.40541
122 2OBD 2OB 5.40541
123 3ILR IXD 5.40541
124 3ILR SGN 5.40541
125 5F3I 5UJ 5.40541
126 4CYI ATP 5.40541
127 4CQE CQE 5.40541
128 3HCH RSM 5.47945
129 2HRL SIA GAL SIA BGC NGA CEQ 5.51181
130 1OGZ EQU 5.6
131 5FU3 BGC BGC BGC 5.66038
132 3GC8 B45 6.08108
133 3E2M E2M 6.08108
134 2I74 MAN MAN MAN MAN 6.08108
135 4FFG 0U8 6.08108
136 3B00 16A 6.08108
137 2E3N 6CM 6.08108
138 4FFG LBS 6.08108
139 5ABX MGP 6.08108
140 4Y8D 49J 6.42857
141 1UNB PN1 6.75676
142 1UNB AKG 6.75676
143 6MPT C30 6.75676
144 5KD6 6C7 6.75676
145 5KD6 LBU 6.75676
146 4YZ5 SLT 6.75676
147 1OIJ AKG 6.75676
148 4LOO SB4 6.75676
149 4U0W 16G 6.75676
150 5ML3 DL3 6.75676
151 1GT4 UNA 6.75676
152 5AYT L6Y 6.75676
153 4RFM 3P6 6.75676
154 2WMC MGP 6.75676
155 5N0L ILE 6.75676
156 5F6U 5VK 6.75676
157 1MJJ HAL 6.75676
158 1OGX EQU 6.87023
159 2HKA C3S 6.92308
160 5XS3 VAL ARG SER ARG ARG CYS LEU ARG LEU 7.14286
161 3E8N ATP 7.43243
162 3E8N VRA 7.43243
163 4BJZ FAD 7.43243
164 4BJZ P3A 7.43243
165 3RWP ABQ 7.43243
166 2XMY CDK 7.43243
167 6D61 4AA 7.43243
168 5E2N V14 7.43243
169 5MZI FAD 7.43243
170 5MZI FYK 7.43243
171 5BU3 4W9 7.43243
172 4CSV STI 7.43243
173 3IAL PR8 7.43243
174 3PG7 PTY 7.43243
175 3TCT 3MI 7.87402
176 5FPX GLY SER SER HIS HIS HIS HIS HIS 7.9646
177 5NBP BGC BGC BGC 8.10811
178 6E08 NAP 8.10811
179 3AGC RCC 8.10811
180 5X7Q GLC GLC GLC GLC GLC 8.10811
181 5X7Q GLC GLC GLC GLC 8.10811
182 1DZK PRZ 8.10811
183 6GVZ CHO 8.10811
184 1UU6 BGC BGC BGC BGC 8.10811
185 1M15 ARG 8.10811
186 1M15 ADP 8.10811
187 2OVR SER LEU ILE PRO TPO PRO ASP LYS 8.10811
188 4F7E 0SH 8.16327
189 3L9R L9Q 8.16327
190 3L9R L9R 8.16327
191 1P0Z FLC 8.39695
192 4M1U A2G MBG 8.57143
193 2CDO GAL AAL GAL AAL GAL AAL 8.78378
194 1EWF PC1 8.78378
195 5I0U DCY 8.78378
196 4WVO 3UZ 9.45946
197 1UMZ BGC BGC XYS BGC XYS GAL 9.45946
198 3SXS PP2 9.45946
199 4LA7 A1O 9.45946
200 1U0A BGC BGC BGC BGC 9.45946
201 1MH5 HAL 9.45946
202 5A3T MMK 9.45946
203 2E56 MYR 9.72222
204 1MHC FME TYR PHE ILE ASN ILE LEU THR LEU 10.101
205 3Q8G PEE 10.1351
206 1OJJ GLC GAL 10.1351
207 3PUR 2HG 10.1351
208 1VA6 P2S 10.1351
209 1VA6 ADP 10.1351
210 4AG8 AXI 10.1351
211 3TAY MN0 10.1351
212 1OJK GLC BGC 10.1351
213 3UG4 AHR 10.1351
214 4KYS VIB 10.1351
215 5BVE 4VG 10.8108
216 1D5Z ACE ALC ARG ALA ODA SER LEU NH2 10.8108
217 2HZQ STR 10.8108
218 3K4Z CBI 11.4865
219 1ZM1 BGC BGC BGC 11.4865
220 4LED XXR 11.4865
221 1ODM ASV 12.1622
222 1QIN GIP 12.1622
223 5H2U 1N1 12.1622
224 6F5U CQN 12.1622
225 5DYO FLU 12.2642
226 4JH6 FCN 12.3188
227 4GJ3 0XP 12.8378
228 5MOB A8S 12.8378
229 5FUI APY 13.6364
230 3MTX PGT 14.1892
231 5O9W AKG 14.1892
232 5TA6 79D 14.1892
233 1NKI PPF 14.8148
234 4QCK ASD 14.8649
235 5FXD H7Y 14.8649
236 4CVZ TYR GLU LEU ASP GLU LYS PHE ASP ARG LEU 15.3061
237 3PFG TLO 15.5405
238 3PFG SAM 15.5405
239 2RG0 CTT 15.5405
240 4HWS 1B3 15.5405
241 2Z77 HE7 15.8273
242 3QUZ QUV 16.1616
243 3RUG DB6 16.1616
244 5FKP 6UL 16.1616
245 3SCM LGN 16.1616
246 3G08 FEE 16.1616
247 4H6B 10Y 16.2162
248 5NEA 8V8 16.8919
249 4WO4 JLS 18
250 5WL1 CUY 18.1818
251 5WL1 D3D 18.1818
252 5U98 1KX 18.1818
253 3HUJ AGH 18.1818
254 5Y72 DST 18.2432
255 5FBN 5WF 18.2432
256 4HWT 1B2 18.2432
257 4BPZ GLC BGC BGC 18.9189
258 5A65 TPP 19.5946
259 5A5W GUO 20.2703
260 5TBM 79A 21.3675
261 5V3D FCN 22.7586
262 3D72 FAD 22.973
263 3IS2 FAD 22.973
264 3M3E GAL A2G NPO 27.7027
265 3VV1 GAL FUC 45.9459
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