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Receptor
PDB id Resolution Class Description Source Keywords
2ZWA 1.7 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF TRNA WYBUTOSINE SYNTHESIZING ENZYME TYW4 SACCHAROMYCES CEREVISIAE TRANSFERASE
Ref.: STRUCTURAL BASIS OF TRNA MODIFICATION WITH CO2 FIXATION AND METHYLATION BY WYBUTOSINE SYNTHESIZING ENZYME TYW4. NUCLEIC ACIDS RES. V. 37 2910 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CIT A:802;
B:802;
Invalid;
Invalid;
none;
none;
submit data
192.124 C6 H8 O7 C(C(=...
EDO A:696;
A:697;
A:698;
B:696;
B:697;
B:698;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
SAH A:801;
B:801;
Valid;
Valid;
none;
none;
submit data
384.411 C14 H20 N6 O5 S c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ZWA 1.7 Å EC: 2.1.1.- CRYSTAL STRUCTURE OF TRNA WYBUTOSINE SYNTHESIZING ENZYME TYW4 SACCHAROMYCES CEREVISIAE TRANSFERASE
Ref.: STRUCTURAL BASIS OF TRNA MODIFICATION WITH CO2 FIXATION AND METHYLATION BY WYBUTOSINE SYNTHESIZING ENZYME TYW4. NUCLEIC ACIDS RES. V. 37 2910 2009
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 60 families.
1 2ZWA - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 2ZW9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 54 families.
1 2ZWA - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 2ZW9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 47 families.
1 2ZWA - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 2ZW9 - SAM C15 H22 N6 O5 S C[S@@+](CC....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SAH; Similar ligands found: 211
No: Ligand ECFP6 Tc MDL keys Tc
1 SAH 1 1
2 5X8 0.759494 0.969697
3 A7D 0.734177 0.926471
4 TT8 0.709302 0.970588
5 DSH 0.692308 0.914286
6 SXZ 0.692308 0.916667
7 DTA 0.666667 0.857143
8 3DH 0.662338 0.869565
9 S8M 0.655556 0.901408
10 SFG 0.635294 0.954545
11 SA8 0.62069 0.915493
12 EEM 0.617977 0.890411
13 MTA 0.615385 0.869565
14 SAI 0.613636 0.955882
15 S7M 0.586957 0.916667
16 36A 0.586538 0.90411
17 K15 0.583333 0.878378
18 ADN 0.573333 0.84058
19 RAB 0.573333 0.84058
20 XYA 0.573333 0.84058
21 62X 0.572917 0.855263
22 5CD 0.571429 0.852941
23 0UM 0.5625 0.876712
24 5N5 0.558442 0.84058
25 A4D 0.551282 0.867647
26 SAM 0.537634 0.916667
27 SMM 0.536842 0.88
28 SSA 0.536842 0.712644
29 KB1 0.534653 0.902778
30 A5D 0.532609 0.857143
31 SIB 0.53125 0.928571
32 EP4 0.530864 0.819444
33 DSZ 0.530612 0.732558
34 GSU 0.53 0.752941
35 A 0.529412 0.763158
36 LMS 0.529412 0.694118
37 AMP 0.529412 0.763158
38 5CA 0.525773 0.712644
39 ME8 0.524752 0.8125
40 M2T 0.52439 0.821918
41 6RE 0.523256 0.824324
42 GJV 0.522727 0.813333
43 AAT 0.515789 0.863014
44 LSS 0.515152 0.696629
45 KAA 0.514852 0.727273
46 J7C 0.511364 0.835616
47 A5A 0.510417 0.697674
48 SON 0.505495 0.805195
49 SRP 0.505155 0.805195
50 F0P 0.504505 0.915493
51 54H 0.5 0.681818
52 VMS 0.5 0.681818
53 ADX 0.5 0.694118
54 CA0 0.5 0.769231
55 AMO 0.5 0.805195
56 5AL 0.5 0.779221
57 KH3 0.5 0.866667
58 NVA LMS 0.49505 0.707865
59 AHX 0.49505 0.753086
60 TSB 0.494949 0.689655
61 53H 0.494949 0.674157
62 G5A 0.494737 0.712644
63 ABM 0.494382 0.74359
64 A2D 0.494382 0.74359
65 ZAS 0.494253 0.808219
66 A6D 0.490196 0.759494
67 8QN 0.49 0.779221
68 GEK 0.49 0.956522
69 GAP 0.489583 0.769231
70 AN2 0.48913 0.734177
71 A3S 0.48913 0.884058
72 S4M 0.488889 0.831169
73 SRA 0.488636 0.746835
74 LAD 0.485437 0.810127
75 52H 0.484848 0.674157
76 A12 0.483516 0.759494
77 BA3 0.483516 0.74359
78 AP2 0.483516 0.759494
79 NEC 0.483146 0.788732
80 AOC 0.483146 0.842857
81 Y3J 0.481481 0.768116
82 VRT 0.479167 0.861111
83 50T 0.478723 0.734177
84 B4P 0.478261 0.74359
85 ADP 0.478261 0.74359
86 5AS 0.478261 0.655556
87 AP5 0.478261 0.74359
88 A3N 0.477778 0.830986
89 YSA 0.476636 0.712644
90 XAH 0.476636 0.768293
91 0XU 0.473684 0.897059
92 AT4 0.473118 0.7375
93 WAQ 0.471154 0.807692
94 NSS 0.470588 0.712644
95 5AD 0.468354 0.791045
96 AU1 0.468085 0.725
97 M33 0.468085 0.734177
98 MAO 0.467391 0.797468
99 TXA 0.466667 0.759494
100 NB8 0.466667 0.775
101 A3G 0.466667 0.871429
102 3AM 0.465909 0.727273
103 DAL AMP 0.465347 0.779221
104 8X1 0.465347 0.707865
105 A3T 0.463158 0.842857
106 ATP 0.463158 0.74359
107 HEJ 0.463158 0.74359
108 ACP 0.463158 0.746835
109 7D7 0.4625 0.785714
110 LEU LMS 0.461538 0.688889
111 9ZA 0.460784 0.740741
112 9ZD 0.460784 0.740741
113 5FA 0.458333 0.74359
114 AQP 0.458333 0.74359
115 AR6 0.458333 0.766234
116 APC 0.458333 0.759494
117 APR 0.458333 0.766234
118 PRX 0.458333 0.746835
119 F2R 0.457627 0.75
120 IOT 0.456897 0.761905
121 4AD 0.456311 0.794872
122 PAJ 0.456311 0.722892
123 WSA 0.45614 0.72093
124 YAP 0.453704 0.794872
125 8PZ 0.453704 0.712644
126 FA5 0.453704 0.805195
127 ADP PO3 0.453608 0.763158
128 ADV 0.453608 0.782051
129 NVA 2AD 0.453608 0.849315
130 SAP 0.453608 0.728395
131 AGS 0.453608 0.728395
132 RBY 0.453608 0.782051
133 AD9 0.453608 0.725
134 PTJ 0.45283 0.731707
135 MHZ 0.452632 0.797468
136 00A 0.451923 0.740741
137 A3P 0.451613 0.74026
138 YLP 0.451327 0.771084
139 7MD 0.45045 0.768293
140 ALF ADP 0.45 0.707317
141 ADP ALF 0.45 0.707317
142 2VA 0.447917 0.819444
143 OOB 0.446602 0.779221
144 ANP 0.444444 0.725
145 T99 0.444444 0.7375
146 ACQ 0.444444 0.746835
147 TAT 0.444444 0.7375
148 P5A 0.443396 0.719101
149 7D5 0.443182 0.708861
150 A1R 0.442308 0.7625
151 YLC 0.439655 0.790123
152 2AM 0.438202 0.717949
153 DLL 0.438095 0.779221
154 ARG AMP 0.4375 0.759036
155 A22 0.436893 0.734177
156 D3Y 0.436893 0.859155
157 ATF 0.435644 0.716049
158 MYR AMP 0.435185 0.746988
159 80F 0.434426 0.75
160 SO8 0.434343 0.808219
161 OAD 0.433962 0.769231
162 3UK 0.433962 0.769231
163 TAD 0.433628 0.765432
164 25A 0.432692 0.74359
165 6YZ 0.431373 0.746835
166 VO4 ADP 0.431373 0.734177
167 ADP VO4 0.431373 0.734177
168 9SN 0.431193 0.731707
169 TYM 0.431034 0.805195
170 B5V 0.429907 0.759494
171 PR8 0.429907 0.8
172 ADQ 0.428571 0.746835
173 YLB 0.42735 0.771084
174 9K8 0.425926 0.67033
175 1ZZ 0.425926 0.746988
176 FYA 0.425926 0.779221
177 3OD 0.425926 0.769231
178 PPS 0.425743 0.674419
179 MAP 0.423077 0.707317
180 A2P 0.421053 0.727273
181 4YB 0.421053 0.735632
182 9X8 0.420561 0.75
183 ADP BMA 0.420561 0.746835
184 TYR AMP 0.419643 0.794872
185 5SV 0.419048 0.731707
186 3NZ 0.416667 0.824324
187 YLA 0.416667 0.771084
188 8Q2 0.415254 0.688889
189 A3R 0.415094 0.7625
190 B5Y 0.414414 0.75
191 B5M 0.414414 0.75
192 48N 0.413793 0.753086
193 LPA AMP 0.413793 0.768293
194 AYB 0.413223 0.761905
195 ACK 0.413043 0.710526
196 QQY 0.413043 0.696203
197 BIS 0.412844 0.719512
198 JB6 0.412844 0.7625
199 PAP 0.41 0.730769
200 DQV 0.408696 0.75641
201 OVE 0.408602 0.7125
202 AMP DBH 0.40708 0.746835
203 4UV 0.40708 0.75
204 3AD 0.406977 0.852941
205 AF3 ADP 3PG 0.40678 0.743902
206 OMR 0.40678 0.738095
207 LAQ 0.405172 0.768293
208 A A 0.40367 0.74359
209 7C5 0.403509 0.789474
210 7MC 0.403361 0.75
211 4UU 0.4 0.75
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2ZWA; Ligand: SAH; Similar sites found with APoc: 492
This union binding pocket(no: 1) in the query (biounit: 2zwa.bio1) has 24 residues
No: Leader PDB Ligand Sequence Similarity
1 1E1M NAP 0.869565
2 1E1M FAD 0.869565
3 1NAA 6FA 1.10906
4 3O26 NDP 1.28617
5 2C5A GDC 1.31926
6 2C5A NAD 1.31926
7 3PT9 SAH 1.43885
8 2IV2 MGD 1.43885
9 4C3Y FAD 1.50943
10 2JHP SAH 1.5528
11 1XTP SAI 1.5748
12 4HXY NDP 1.59817
13 1RRV TYD 1.68269
14 1DMR PGD 1.72662
15 4YNU FAD 1.75131
16 1NJR XYL 1.76056
17 1QO8 FAD 1.76678
18 5DNK SAH 1.80505
19 1V6A TRE 1.80723
20 5K0A FAD 1.81818
21 3OU2 SAH 1.83486
22 4TQG NDP 1.85759
23 1BC5 SAH 1.85874
24 4OJP MAL 1.8705
25 3QOX SAH 1.87793
26 1GZ6 NAI 1.88088
27 5W7K SAH 1.92308
28 4KRG SAH 1.93133
29 1FP2 SAH 1.98864
30 1FP2 HMO 1.98864
31 1O5I NAD 2.00803
32 3AXB FAD 2.00893
33 3AXB PRO 2.00893
34 1G55 SAH 2.04082
35 1ELI PYC 2.05656
36 2FR1 NDP 2.05761
37 5OSW DIU 2.05832
38 4NTD FAD 2.05882
39 5HV7 RBL 2.06422
40 1ZBQ NAD 2.14067
41 1AE1 NAP 2.1978
42 3QWI NAP 2.22222
43 3QWI CUE 2.22222
44 2YY7 NAD 2.24359
45 3PFG TLO 2.28137
46 3PFG SAM 2.28137
47 3LST SAH 2.29885
48 3RKR NAP 2.30216
49 1NFQ NAI 2.30769
50 4MIG G3F 2.31481
51 4XQC 13D 2.31579
52 4XQC NAD 2.31579
53 4E70 N7I 2.31959
54 4R6W PC 2.32558
55 4R6W SAH 2.32558
56 1SQF SAM 2.331
57 3ELW SAM 2.33333
58 3ELW GP3 2.33333
59 5YSS NAD 2.34375
60 2WSB NAD 2.3622
61 5F8F SFG 2.38727
62 1RPN NDP 2.38806
63 5MW4 5JU 2.39521
64 5XNC MTA 2.42588
65 1UZN NAP 2.42915
66 5MLR GRQ 2.43309
67 5MLR NAP 2.43309
68 5JJR SAH 2.44604
69 1G0N NDP 2.4735
70 1G0N PHH 2.4735
71 1UAY ADN 2.47934
72 4DSG FAD 2.47934
73 4DSG UDP 2.47934
74 6F7L FAD 2.48869
75 1I9G SAM 2.5
76 1XG5 NAP 2.50896
77 3SJU NDP 2.50896
78 2ZXI FAD 2.51177
79 5KOK R9T 2.51889
80 5KOK SAH 2.51889
81 5KOK S9T 2.51889
82 3EVF GTA 2.52708
83 3EVF SAH 2.52708
84 6GKV SAH 2.5641
85 5W7R SAH 2.58993
86 3S1S SAH 2.58993
87 5W7R 9Z7 2.58993
88 4ITU NAI 2.60223
89 4ITU 1HS 2.60223
90 1A99 PUT 2.61628
91 6C5B SAH 2.6393
92 1E5Q NDP 2.66667
93 1Z3C SA8 2.68456
94 3FPF TNA 2.68456
95 3FPF MTA 2.68456
96 5X62 SAH 2.70936
97 1V59 NAD 2.71967
98 3HP8 SUC 2.72727
99 4Z24 FAD 2.76074
100 5XWV NDP 2.82258
101 5XWV 8H6 2.82258
102 1DL5 SAH 2.83912
103 5ERG SAM 2.86885
104 2Q0L FAD 2.89389
105 1TZD ADP 2.90909
106 2GMH FAD 2.91096
107 6F9Q NAD 2.94118
108 2YVK MRU 2.94118
109 3T7S SAM 2.98507
110 5BW4 SAM 2.99625
111 5CUQ NSC 2.99625
112 3OIG NAD 3.00752
113 1XHL NDP 3.0303
114 4REP FAD 3.0303
115 1XSE NDP 3.05085
116 1U7T TDT 3.06513
117 1J1R ADE 3.06513
118 1E3W NAD 3.06513
119 6B3A SAM 3.06748
120 2JB2 PHE 3.06748
121 2JB2 FAD 3.06748
122 1E6W NAD 3.07692
123 1ZGA SAH 3.08123
124 1JQD SAH 3.08219
125 2AOT SAH 3.08219
126 1JQD HSM 3.08219
127 5FEU NAP 3.09278
128 3O03 NAP 3.09278
129 4URN NOV 3.11111
130 6ECT SAM 3.11526
131 6DUB SAH 3.15315
132 4MOP 2H5 3.15956
133 5YJI 8WO 3.16901
134 5YJI SAH 3.16901
135 5YJF 8WO 3.16901
136 5YJF SAH 3.16901
137 3SJ7 NDP 3.1746
138 5OC1 FAD 3.18584
139 2Q28 ADP 3.19149
140 1XKQ NDP 3.21429
141 3WXB NDP 3.22581
142 3NUG NAD 3.23887
143 3GEG NAD 3.23887
144 4MO2 FDA 3.26087
145 4MO2 FAD 3.26087
146 2B4Q NAP 3.26087
147 5I7S E9P 3.26087
148 5I7S NAD 3.26087
149 4CQM NAP 3.27869
150 1EDO NAP 3.27869
151 5IM3 DTP 3.30935
152 4Q0A 4OA 3.31126
153 3VRV YSD 3.32103
154 4Q9N NAI 3.3557
155 4UZI IMD 3.36323
156 4NEC SAH 3.40909
157 2A14 SAH 3.42205
158 6C8R EQV 3.43008
159 6C8R SAH 3.43008
160 6ARJ SAH 3.4384
161 6ARJ BW4 3.4384
162 5DX8 SFG 3.4384
163 5DX1 SFG 3.4384
164 5DXA SFG 3.4384
165 5DX0 SFG 3.4384
166 5DWQ SFG 3.4384
167 1EK6 UPG 3.44828
168 1EK6 NAI 3.44828
169 1NW5 SAM 3.44828
170 4YAG NAI 3.46021
171 4BLW AMP 3.46021
172 4BLW SAH 3.46021
173 1V7Z CRN 3.46154
174 1G60 SAM 3.46154
175 1TPY SAH 3.48432
176 3A28 NAD 3.48837
177 3AFN NAP 3.48837
178 4EUE NAI 3.58852
179 4K26 SFF 3.62319
180 4K26 NDP 3.62319
181 5O42 NAD 3.64964
182 5O42 9JW 3.64964
183 5O42 BGC 3.64964
184 5Y1G AKB 3.65854
185 5Y1G NAD 3.65854
186 3AQT RCO 3.67347
187 2BD0 NAP 3.68852
188 2PXX SAH 3.72093
189 5E1M PRO PRO LYS ARG ILE ALA 3.73444
190 5E1M SAH 3.73444
191 1EU1 MGD 3.74101
192 3H8V ATP 3.76712
193 3C3Y SAH 3.79747
194 5DF1 58X 3.80435
195 5DF1 NAP 3.80435
196 5MGZ SAH 3.81356
197 1I8T FAD 3.81471
198 1QG6 TCL 3.83142
199 1QG6 NAD 3.83142
200 1KPG SAH 3.83275
201 1KPH SAH 3.83275
202 5W7M SAH 3.84615
203 2AE2 PTO 3.84615
204 2AE2 NAP 3.84615
205 4ZRN NAD 3.84615
206 2ZAT NAP 3.84615
207 5FUB SAH 3.85757
208 6CI9 NAP 3.861
209 5GWX SAR 3.87324
210 5GWX SAM 3.87324
211 4D42 NAP 3.90071
212 4D42 W0I 3.90071
213 2OCI TYC 3.93701
214 3H2B SAH 3.94089
215 5THY SAH 3.95062
216 5THZ SAH 3.95062
217 4N49 SAM 3.97196
218 1WMA NDP 3.98551
219 1WMA AB3 3.98551
220 4O0L NDP 4
221 1JA9 NDP 4.0146
222 5J60 FAD 4.0625
223 5L4S 6KX 4.08805
224 5L4S NAP 4.08805
225 2PX8 SAH 4.08922
226 5O98 NAP 4.10095
227 3QVP FAD 4.11664
228 5JGL SAM 4.15225
229 6FDF SAH 4.19162
230 2OO0 XAP 4.24628
231 3GCZ SAM 4.25532
232 5ICE 2H4 4.26136
233 5ICE SAH 4.26136
234 5HJM MTA 4.26136
235 4Y9D NAI 4.2623
236 5CG1 NAD BBN 4.2623
237 5FFF NAP 4.28016
238 5FFF 5XC 4.28016
239 5Z75 NAD 4.28135
240 4J1Q NDP 4.31034
241 3ICC NAP 4.31373
242 3A25 SAM 4.31894
243 2OKL BB2 4.32432
244 3V1U NAD 4.329
245 3RJ5 NAD 4.33071
246 3GWZ SAH 4.33604
247 3GXO SAH 4.33604
248 3GXO MQA 4.33604
249 5MPT SAH 4.34783
250 2PD4 NAD 4.36364
251 2PD4 DCN 4.36364
252 2ZIF SAM 4.3771
253 4KRI SAH 4.38799
254 1JQ3 AAT 4.39189
255 4NBU NAI 4.4
256 2VDV SAM 4.47154
257 5LA1 XYP 4.48065
258 2EJU SAH 4.49735
259 4POO SAM 4.5
260 5WUW NAP 4.52962
261 4A6D SAM 4.53258
262 4DCM SAM 4.53333
263 2X2T GAL NGA 4.57516
264 4UCI SAM 4.57831
265 5F2K OCA 4.61957
266 5F2K SAH 4.61957
267 4PIO AVI 4.64396
268 4PIO SAH 4.64396
269 3ABI NAD 4.65753
270 1UWK NAD 4.66786
271 1UWK URO 4.66786
272 4AZW SAM 4.67091
273 5YF1 SFG 4.69613
274 5YF1 8V0 4.69613
275 3MB5 SAM 4.70588
276 2YX1 SFG 4.7619
277 1U3G ADP 4.7619
278 5THQ NDP 4.77941
279 3HDY GDU 4.78589
280 3HDY FDA 4.78589
281 3HDY FAD 4.78589
282 1SQL GUN 4.79452
283 5VN0 FAD 4.82625
284 5VN0 NAI 4.82625
285 3BP1 GUN 4.82759
286 2JAH NDP 4.8583
287 2JAP NDP 4.8583
288 1I1N SAH 4.86726
289 5WP4 SAH 4.88798
290 2WPB ZZI 4.93421
291 5GT9 NAP 4.94297
292 2W58 ADP 4.9505
293 1ZEM NAD 4.96183
294 2PWY SAH 5.03876
295 3OJF IMJ 5.05837
296 3OJF NDP 5.05837
297 6ECU SAH 5.06329
298 5OVK NDP 5.07812
299 6ECW SAH 5.07937
300 5MTE BB2 5.10949
301 2JG1 TA6 5.17986
302 1Y8Q ATP 5.20231
303 1L3I SAH 5.20833
304 1YXM ADE 5.28053
305 3Q87 SAM 5.29412
306 3P2E SAH 5.33333
307 5K7U SAM 5.33333
308 3U4C NDP 5.33808
309 1XDS SAM 5.34759
310 1E6E FAD 5.46875
311 4FN4 NAD 5.51181
312 3VSE SAH 5.52764
313 5T67 JHZ 5.52885
314 5T67 SAH 5.52885
315 1JG3 ADN 5.53191
316 4KIB SAH 5.60224
317 1QZZ SAM 5.61497
318 5IL1 SAM 5.66038
319 1FUT 2GP 5.66038
320 3A4V NAD 5.67823
321 3A4V PYR 5.67823
322 4LWP SAH 5.70652
323 4O1M NAD 5.71429
324 1VE3 SAM 5.72687
325 1QAN SAH 5.7377
326 3BGD SAH 5.7554
327 3BGD PM6 5.7554
328 3TKA SAM 5.76369
329 5E9W SAH 5.76923
330 1U2Z SAH 5.77367
331 3C6K MTA 5.77428
332 3C6K SPD 5.77428
333 6BWL NAD 5.79268
334 5EJ2 NAD 5.84416
335 1RL4 BRR 5.85106
336 3LKZ SFG 5.919
337 4ZA2 NAD 5.92885
338 1XCL SAH 5.95745
339 1LQY BB2 5.97826
340 1SNY NAP 5.99251
341 3FZG SAM 6
342 6F97 FAD 6.02637
343 2E7Z MGD 6.04317
344 3ZV6 4HB 6.04982
345 3ZV6 NAD 6.04982
346 1V35 NAI 6.07903
347 4DMG SAM 6.10687
348 1OAA OAA 6.17761
349 3OID NDP 6.20155
350 1FK8 NAD 6.22568
351 4OHU 2TK 6.22837
352 4OHU NAD 6.22837
353 5L95 AMP 6.25
354 6EL3 NAP 6.29921
355 5ULP KB1 6.34328
356 1VL8 NAP 6.36704
357 6B92 SAH 6.46258
358 1BDB NAD 6.4982
359 3L9W AMP 6.53753
360 5K4W NAI 6.54206
361 5K4W THR 6.54206
362 5BJX NAD 6.55738
363 5BJX UDP 6.55738
364 3P9C SAH 6.59341
365 4NBW NAD 6.61479
366 5FTW SAH 6.64062
367 1NNU TCT 6.66667
368 1NNU NAD 6.66667
369 4NBT NAD 6.66667
370 3WMX NAD 6.70391
371 5UFN SAH 6.72269
372 3HB5 NAP 6.72783
373 5FA8 SAM 6.8323
374 4URF NAD 6.85484
375 2CDU FAD 6.85841
376 2NV2 GLN 6.86275
377 2WA2 SAM 6.88406
378 5KMS NAD 6.91358
379 5KMS FAD 6.91358
380 3CH6 311 6.99301
381 3CH6 NAP 6.99301
382 5NMX NAP 7.05882
383 5NMX FAD 7.05882
384 5XLX SAH 7.0922
385 1LSS NAD 7.14286
386 2CBZ ATP 7.173
387 5BSZ SAH 7.2
388 6BQ6 TER 7.25076
389 4RVG TYD 7.277
390 4RVG SAM 7.277
391 4XUC SAM 7.33945
392 4XUC 43G 7.33945
393 3TN7 NJP 7.393
394 2ZFU SAH 7.44186
395 4YMH SAH 7.5
396 6AYI C3G 7.53769
397 4IRP UDP 7.56972
398 4FC7 NAP 7.58123
399 4FC7 COA 7.58123
400 5TVI O8N 7.6087
401 3G5K BB2 7.65027
402 4X7Y SAH 7.66423
403 3MAG SAH 7.81759
404 2GDZ NAD 7.86517
405 5NM7 GLY 7.89474
406 2RH4 EMO 7.94224
407 2DTX BMA 7.95455
408 4GLL NAD 8.01187
409 2UYQ SAM 8.06452
410 5FWA J7C 8.07175
411 5E72 SAM 8.09249
412 3WXL ADP 8.10811
413 3HVJ 705 8.1448
414 1T0S BML 8.48485
415 5JE0 SAH 8.50202
416 5JE0 AZ8 8.50202
417 1IY8 NAD 8.61423
418 5U19 SAH 8.79765
419 5U19 827 8.79765
420 3TKY SAH 8.96739
421 2XVM SAH 9.04523
422 4J7U YTZ 9.06475
423 4J7U NAP 9.06475
424 5GM1 SAH 9.09091
425 3VYW SAM 9.09091
426 2DPM SAM 9.15493
427 1FP1 SAH 9.4086
428 1PR9 NAP 9.42623
429 3D3W NAP 9.42623
430 4RPL 3UC 9.52381
431 4RPL FAD 9.52381
432 2CFC NAD 9.6
433 2OBF F83 9.68858
434 2OBF SAH 9.68858
435 4YUW 4JU 9.86842
436 4YUW S4M 9.86842
437 3BXO SAM 10.0418
438 3MQ2 SAH 10.0917
439 4JE7 BB2 10.1523
440 1GEG NAD 10.1562
441 5E70 RCD 10.2941
442 4II2 ATP 10.4294
443 3X01 AMP 10.4326
444 4XCP PLM 10.5882
445 1WZ1 DNS 10.6195
446 5T2U NAP 10.8871
447 2HMT NAI 11.1111
448 2UVO NAG 11.1111
449 2UVO NDG 11.1111
450 1KYZ SAH 11.2329
451 1KYZ FER 11.2329
452 5E8J SAH 11.3636
453 5Z2L NDP 11.4286
454 3DXY SAM 11.4679
455 6F5Z SAH 11.4754
456 2BGM NAJ 11.5108
457 4PNE SAH 11.5894
458 2V6G NAP 11.8132
459 1L1E SAH 11.8467
460 3G2O SAM 12.0401
461 3LCV SAM 12.0996
462 2P41 SAH 12.1311
463 2AG5 NAD 12.1951
464 3JWH SAH 12.9032
465 2RI1 GLP 13.1915
466 4OBW SAM 13.2296
467 3EVG SAH 13.4545
468 1H5Q NAP 13.5849
469 2BZG SAH 13.7931
470 1YY5 FAD 13.8402
471 1Q0S SAH 13.8996
472 4HMX FMN 14.4186
473 4JOB TLA 14.6465
474 6GFK SAH 14.741
475 4YAC NAI 14.8148
476 3ML1 MGD 14.8148
477 3KIF GDL 15.0943
478 1F3L SAH 15.2648
479 1R6D NAD 15.4303
480 1R6D DAU 15.4303
481 2EWM NAD 16.4659
482 3KP6 SAL 16.5563
483 2WYV NAD 18.0077
484 5LOG SAH 18.0258
485 4DR9 BB2 18.2292
486 1APZ ASP 18.5185
487 5GWT NAD 20.5036
488 5GWT SIN 20.5036
489 1Z6Z NAP 22.3404
490 4GQB 0XU 22.7273
491 5FA5 MTA 25
492 5YEC ATP 25.2101
Pocket No.: 2; Query (leader) PDB : 2ZWA; Ligand: SAH; Similar sites found with APoc: 21
This union binding pocket(no: 2) in the query (biounit: 2zwa.bio2) has 25 residues
No: Leader PDB Ligand Sequence Similarity
1 3AYI FAD 2.30216
2 3AYI HCI 2.30216
3 4D79 ATP 2.53623
4 6G5J EM8 3.63636
5 5WGR FAD 5.09745
6 5NXX 3Q7 5.22388
7 5F90 GLA GAL BGC 5VQ 5.76923
8 1R18 SAH 6.1674
9 5N0J FAD 6.26781
10 2IID FAD 6.4257
11 2IID PHE 6.4257
12 1GPE FAD 6.47359
13 3AD8 PYC 7.07071
14 3AD8 FAD 7.07071
15 2GAG FOA 7.07071
16 2GAG FAD 7.07071
17 2Q7V FAD 7.07692
18 4UP5 94W 8.08081
19 4DD8 BAT 8.65385
20 5XG5 A2G 10.3448
21 2XRH NIO 13
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