Receptor
PDB id Resolution Class Description Source Keywords
2ZX2 1.8 Å NON-ENZYME: OTHER RHAMNOSE-BINDING LECTIN CSL3 ONCORHYNCHUS KETA LECTIN RHAMNOSE INNATE IMMUNITY IMMUNE SYSTEM SUGAR BINDING PROTEIN
Ref.: STRUCTURE OF RHAMNOSE-BINDING LECTIN CSL3: UNIQUE PSEUDO-TETRAMERIC ARCHITECTURE OF A PATTERN RECOGNITION PROTEIN J.MOL.BIOL. V. 391 390 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PO4 A:196;
A:197;
B:196;
B:197;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
RAM A:198;
B:198;
B:199;
Valid;
Valid;
Valid;
none;
none;
none;
submit data
164.156 C6 H12 O5 C[C@H...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2ZX2 1.8 Å NON-ENZYME: OTHER RHAMNOSE-BINDING LECTIN CSL3 ONCORHYNCHUS KETA LECTIN RHAMNOSE INNATE IMMUNITY IMMUNE SYSTEM SUGAR BINDING PROTEIN
Ref.: STRUCTURE OF RHAMNOSE-BINDING LECTIN CSL3: UNIQUE PSEUDO-TETRAMERIC ARCHITECTURE OF A PATTERN RECOGNITION PROTEIN J.MOL.BIOL. V. 391 390 2009
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1256 families.
1 2ZX3 - BGC GLA n/a n/a
2 2ZX2 - RAM C6 H12 O5 C[C@H]1[C@....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1068 families.
1 2ZX3 - BGC GLA n/a n/a
2 2ZX2 - RAM C6 H12 O5 C[C@H]1[C@....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 922 families.
1 2ZX3 - BGC GLA n/a n/a
2 2ZX2 - RAM C6 H12 O5 C[C@H]1[C@....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: RAM; Similar ligands found: 9
No: Ligand ECFP6 Tc MDL keys Tc
1 G6D 1 1
2 XXR 1 1
3 FUL 1 1
4 FUC 1 1
5 RAM 1 1
6 FCA 1 1
7 RM4 1 1
8 FCB 1 1
9 FUF 0.424242 0.846154
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2ZX2; Ligand: RAM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 2zx2.bio1) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
Pocket No.: 2; Query (leader) PDB : 2ZX2; Ligand: RAM; Similar sites found: 100
This union binding pocket(no: 2) in the query (biounit: 2zx2.bio1) has 12 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1IXE COA 0.009883 0.42588 None
2 1ZUI SKM 0.03861 0.41451 None
3 2PYY GLU 0.0139 0.40664 None
4 1F2U ATP 0.03144 0.40654 None
5 3QKT ANP 0.03347 0.40418 None
6 1YZG GDP 0.02037 0.40211 None
7 4BUZ OCZ 0.04883 0.40187 None
8 4BUZ OAD 0.04883 0.40187 None
9 4BUZ NAD 0.04244 0.40187 None
10 1ZJ6 G3D 0.0208 0.40152 None
11 1R4A GNP 0.03964 0.40136 None
12 1RRC ADP 0.01008 0.40574 1.02564
13 2EW5 Y12 0.003443 0.4524 1.10497
14 1MR3 G3D 0.005463 0.43221 1.10497
15 2JG1 ANP 0.01467 0.4178 1.53846
16 3A4M ADP 0.01277 0.40656 1.53846
17 1U7Z PMT 0.04772 0.40039 1.53846
18 4S3R 7SA 0.006825 0.45503 2.05128
19 5KUT GDP 0.006546 0.42813 2.1164
20 2CXG GLC GLC 0.004752 0.42439 2.5641
21 1A59 COA 0.0176 0.41284 2.5641
22 2FAV APR 0.03359 0.40219 2.77778
23 4NBI D3Y 0.02715 0.40811 3.04878
24 2NYR SVR 0.03814 0.44235 3.07692
25 1WVC CTP 0.01171 0.43272 3.07692
26 1N0U SO1 0.01418 0.41586 3.07692
27 2ZE7 AMP 0.02239 0.41288 3.07692
28 4C4A SAH 0.03058 0.40356 3.07692
29 2ZE7 DST 0.04682 0.40044 3.07692
30 1CT9 GLN 0.0182 0.40007 3.07692
31 4OI4 ATP 0.02272 0.40667 3.47826
32 4JSR 1NQ 0.03601 0.42854 3.58974
33 2OFW ADX 0.03205 0.41972 3.58974
34 1CSI OAA 0.04294 0.4152 3.58974
35 4QM7 GTP 0.01444 0.40668 4.09357
36 4B0T ADP 0.01652 0.42007 4.10256
37 1VB3 KPA 0.01043 0.4075 4.10256
38 4B74 1LH 0.03063 0.40232 4.10256
39 4YEF 4CQ 0.01688 0.42938 4.49438
40 3UIE ANP 0.004594 0.44005 4.61538
41 3G5S GSH 0.007228 0.41956 4.61538
42 1ME8 RVP 0.04581 0.40886 4.61538
43 5IXJ THR 0.02893 0.40814 4.61538
44 2IV2 2MD 0.04384 0.40534 4.61538
45 2PL3 ADP 0.01509 0.40373 4.61538
46 3QF7 ANP 0.02914 0.40089 4.61538
47 5F90 GLA GAL 0.005497 0.40448 5.12821
48 5F90 GLA GAL BGC 5VQ 0.005613 0.4042 5.12821
49 3ZFD ANP 0.0212 0.40391 5.12821
50 1UJ2 ADP 0.0402 0.40385 5.12821
51 1UJ2 C5P 0.04291 0.40209 5.12821
52 5F90 LMR 0.003897 0.40112 5.12821
53 3NBC LAT 0.01025 0.40173 5.40541
54 1OS1 ATP 0.003729 0.46251 5.64103
55 1OS1 PYR 0.003953 0.46251 5.64103
56 1M7G ADP 0.01554 0.42922 5.64103
57 1M7G ADX 0.01973 0.42582 5.64103
58 3JQ9 NAP 0.04346 0.40152 5.64103
59 2PEZ DAT 0.02186 0.42414 6.14525
60 3HRD MCN 0.03766 0.40387 6.15385
61 1S8G DAO 0.01563 0.40271 6.61157
62 4D86 ADP 0.01734 0.41662 6.66667
63 2CKM AA7 0.04492 0.41391 6.66667
64 1XKV ATP 0.01387 0.41299 6.66667
65 3H0L ADP 0.009188 0.41231 6.66667
66 2D2I NAP 0.02284 0.41123 6.66667
67 3PT9 SAH 0.01833 0.40791 6.66667
68 1KY3 GDP 0.022 0.40289 7.14286
69 1XMV ADP 0.007036 0.42726 7.17949
70 2VF7 ADP 0.01755 0.40661 7.17949
71 4J3L AJ5 0.03308 0.40091 7.17949
72 2ZR9 DTP 0.004411 0.43581 7.69231
73 4OB6 S2T 0.01305 0.41192 7.69231
74 1OE0 TTP 0.03596 0.40556 7.69231
75 3N9R TD3 0.01438 0.40134 7.69231
76 5EP2 AZU 0.001495 0.46971 7.8125
77 4N4J HG1 0.02711 0.41562 8.20513
78 3X0D SAH 0.03265 0.40206 8.20513
79 1VHT BA3 0.01955 0.403 8.71795
80 4JWH SAH 0.03855 0.40251 8.71795
81 2BFR ADP 0.02328 0.40895 9.375
82 1FZQ GDP 0.01954 0.40065 9.39227
83 3O0Q TTP 0.03663 0.4325 9.74359
84 3O0Q ADN 0.03746 0.4325 9.74359
85 2Z48 NGA 0.001813 0.42302 9.74359
86 2Z48 A2G 0.005114 0.41126 9.74359
87 3QV1 NAD 0.03078 0.40536 9.74359
88 4MKG AP5 0.04033 0.41635 10.2564
89 2FH5 GTP 0.02493 0.4075 10.2703
90 1W0J ADP 0.01181 0.41985 10.7692
91 2V7Q ATP 0.01264 0.41615 10.7692
92 1W0J ADP BEF 0.02736 0.40219 10.7692
93 2JLR ANP 0.02643 0.40027 10.7692
94 3ZIA ATP 0.007706 0.42581 11.2821
95 3ZIA ADP 0.01119 0.42147 11.2821
96 2QG6 NMN 0.01717 0.42167 12.8205
97 5MDH NAD 0.04188 0.40471 13.3333
98 4J5R A1R 0.02858 0.40735 17.1233
99 3FYH ADP 0.002703 0.46087 17.4359
100 2GDJ ANP 0.003947 0.43366 17.4359
Pocket No.: 3; Query (leader) PDB : 2ZX2; Ligand: RAM; Similar sites found: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 3) in the query (biounit: 2zx2.bio1) has 11 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
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