Receptor
PDB id Resolution Class Description Source Keywords
3A99 1.6 Å EC: 2.7.11.1 STRUCTURE OF PIM-1 KINASE CRYSTALLIZED IN THE PRESENCE OF P2 CARBOXY-TERMINAL PEPTIDE HOMO SAPIENS PIM-1 P27KIP1 PEPTIDE DRUG PROSTATE CANCER TRANSFERASE
Ref.: CELL-PERMEABLE CARBOXYL-TERMINAL P27(KIP1) PEPTIDE ANTI-TUMOR ACTIVITY BY INHIBITING PIM-1 KINASE J.BIOL.CHEM. V. 286 2681 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ANP A:501;
Valid;
none;
submit data
506.196 C10 H17 N6 O12 P3 c1nc(...
MG A:401;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4N70 2.1 Å EC: 2.7.11.1 PIM1 COMPLEXED WITH A PYRIDYLCARBOXAMIDE HOMO SAPIENS KINASE PHOSPHORYLATION TRANSFERASE-TRANSFERASE INHIBITOR C
Ref.: STRUCTURE GUIDED OPTIMIZATION, IN VITRO ACTIVITY, A VIVO ACTIVITY OF PAN-PIM KINASE INHIBITORS. ACS MED CHEM LETT V. 4 1193 2013
Members (68)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 107 families.
1 1XR1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4MBI - 26K C13 H17 N7 CN(C)CCNc1....
3 4MTA - 2D2 C12 H10 O3 Cc1c(cc(o1....
4 3VBT ic50 = 37 uM 0F9 C9 H7 Cl N2 O c1cc(c(cc1....
5 1YXX - LI7 C14 H10 N2 O2 c1ccc2c(c1....
6 5IIS Ki < 0.001 uM 6CB C23 H19 F N6 O Cc1cc(cc(n....
7 4K1B Ki = 0.003 nM 1OC C26 H24 F2 N8 O c1ccc(c(c1....
8 4XH6 ic50 = 2.71 uM HUL C16 H12 O6 COc1c(cc2c....
9 1YXU - AMP C10 H14 N5 O7 P c1nc(c2c(n....
10 1XWS - BI1 C25 H24 N4 O2 CN(C)CCCn1....
11 3R04 ic50 = 0.12 uM UNQ C19 H20 N4 O3 c1cc2c(cc1....
12 5IPJ ic50 = 0.3 nM 6CD C20 H23 N5 O2 C[C@@H]1c2....
13 2C3I Kd = 25 nM IYZ C18 H18 N4 O CC(=O)c1cc....
14 3VBW ic50 = 6 uM 0FN C10 H5 N O2 c1ccc2c(c1....
15 3F2A ic50 = 57 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
16 4WT6 ic50 = 0.012 uM 3U6 C20 H20 N6 S c1cc(nc(c1....
17 4N70 Ki = 0.001 nM 2HX C23 H22 F3 N5 O2 C[C@H]1CN(....
18 4WRS ic50 = 0.4 nM 3U1 C24 H21 F2 N5 O c1cc(c(c(c....
19 2XIX - XIX C2 H5 N5 c1([nH]nc(....
20 2J2I ic50 = 0.2 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
21 3VBQ ic50 = 470 pM 0F5 C20 H23 N5 O2 S c1cc(cc(c1....
22 2OBJ ic50 = 0.05 uM VRV C18 H11 Br N2 O2 c1ccc(cc1)....
23 2O3P ic50 = 1.1 uM QUE C15 H10 O7 c1cc(c(cc1....
24 3VBY ic50 = 28 uM 0FR C13 H9 N O2 c1ccc2c(c1....
25 2XIY - XIY C8 H8 N2 O c1ccc2c(c1....
26 4A7C ic50 = 0.006 uM E46 C18 H19 F3 N6 O c1cc(cc(c1....
27 3BGQ Ki = 11 nM VX2 C18 H18 F3 N5 c1cc(cc(c1....
28 3R02 ic50 = 0.001 uM UNM C15 H17 Br N2 O3 c1c2cc(oc2....
29 4K18 Ki = 1.1 nM 1OB C21 H14 F N5 O2 c1cc(ccc1C....
30 5DIA - 5E6 C22 H23 N7 c1cc(nc(c1....
31 5KZI ic50 = 0.07 nM 6YN C22 H21 F2 N7 c1cc(c(c(c....
32 2BIK - BI1 C25 H24 N4 O2 CN(C)CCCn1....
33 4BZN ic50 = 1.441 uM UGX C18 H23 N3 O2 S CC(C)(C)CN....
34 3VBV ic50 = 10 uM 0FK C10 H8 N2 O2 c1cc2ccc(n....
35 3UIX ic50 = 0.151 uM Q17 C17 H18 N4 O c1ccc2c(c1....
36 1YXV - LI6 C10 H9 N O3 CN1c2ccccc....
37 3UMW ic50 = 3 nM 596 C22 H22 N4 O3 COc1ccc2c(....
38 1YHS ic50 = 0.01 uM STU C28 H26 N4 O3 C[C@@]12[C....
39 2XJ1 Kd = 28 nM XJ1 C19 H22 N4 O2 c1cc(cc(c1....
40 2O64 Kd = 0.34 uM MYU C15 H10 O8 c1cc(c(cc1....
41 4ALW ic50 = 27 nM HY7 C16 H17 Br N4 O2 CN1CCN(CC1....
42 3BGZ Ki = 0.55 uM VX3 C21 H15 N O2 c1ccc(cc1)....
43 2O63 Kd = 0.78 uM MYC C15 H10 O8 c1c(cc(c(c....
44 5V82 Ki = 0.07 nM 96Y C21 H19 F2 N7 Cc1cncc(n1....
45 3VC4 ic50 = 24 nM 0FS C11 H6 F3 N O2 S c1cc(cc(c1....
46 5DHJ Ki = 0.2 uM 5E5 C12 H10 N4 Cc1c2cc(nc....
47 2XIZ - XIZ C8 H7 N O2 c1cnccc1C=....
48 1YI3 ic50 = 4 uM LY2 C19 H17 N O3 c1ccc(cc1)....
49 2XJ2 Kd = 66 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
50 1YI4 - ADN C10 H13 N5 O4 c1nc(c2c(n....
51 3R00 ic50 = 8.5 uM UNJ C9 H5 Br O3 c1cc2c(cc1....
52 3A99 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
53 3C4E ic50 ~ 100 uM C4E C13 H11 N3 c1ccc(cc1)....
54 3MA3 ic50 = 60 nM 01I C16 H8 O6 c1cc2c(cc(....
55 3VBX ic50 = 17 uM 0FO C9 H5 Br O3 c1cc2c(cc1....
56 5DGZ Ki = 14 nM L20 C24 H23 N5 O Cc1c2cc(cc....
57 2OI4 ic50 = 2.5 nM JM1 C23 H12 F N3 O3 Ru c1ccc2c(c1....
58 5EOL ic50 = 0.3 nM 5QO C21 H21 N5 O Cc1c2nc3c(....
59 3WE8 - RUI C18 H7 N2 O2 Ru c1cc2c3c4c....
60 3BWF ic50 = 0.6 nM DWC C23 H9 N3 O4 Os c1cc2c3c(c....
61 4WSY ic50 = 0.017 uM 3U5 C19 H13 N5 S c1ccc2c(c1....
62 4BZO ic50 = 0.013 uM 676 C22 H22 F N5 O2 c1ccc(cc1)....
63 5DWR Ki < 0.001 uM 5H7 C24 H23 F3 N4 O C[C@H]1C[C....
64 4XHK ic50 = 5 nM 3YR C19 H16 F2 N4 O2 S c1cc(c(c(c....
65 4K0Y Ki = 15 nM 1OA C18 H18 F N5 O2 c1cc(ccc1N....
66 4DTK ic50 < 0.004 uM 7LI C18 H23 N3 O3 S CC(C)Oc1cc....
67 4N6Z Ki = 16 nM 2HW C15 H19 N7 O c1cncc(c1N....
68 4AS0 - RPS C20 H19 N2 O3 Ru S3 c1c2c(cc3c....
70% Homology Family (68)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 82 families.
1 1XR1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4MBI - 26K C13 H17 N7 CN(C)CCNc1....
3 4MTA - 2D2 C12 H10 O3 Cc1c(cc(o1....
4 3VBT ic50 = 37 uM 0F9 C9 H7 Cl N2 O c1cc(c(cc1....
5 1YXX - LI7 C14 H10 N2 O2 c1ccc2c(c1....
6 5IIS Ki < 0.001 uM 6CB C23 H19 F N6 O Cc1cc(cc(n....
7 4K1B Ki = 0.003 nM 1OC C26 H24 F2 N8 O c1ccc(c(c1....
8 4XH6 ic50 = 2.71 uM HUL C16 H12 O6 COc1c(cc2c....
9 1YXU - AMP C10 H14 N5 O7 P c1nc(c2c(n....
10 1XWS - BI1 C25 H24 N4 O2 CN(C)CCCn1....
11 3R04 ic50 = 0.12 uM UNQ C19 H20 N4 O3 c1cc2c(cc1....
12 5IPJ ic50 = 0.3 nM 6CD C20 H23 N5 O2 C[C@@H]1c2....
13 2C3I Kd = 25 nM IYZ C18 H18 N4 O CC(=O)c1cc....
14 3VBW ic50 = 6 uM 0FN C10 H5 N O2 c1ccc2c(c1....
15 3F2A ic50 = 57 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
16 4WT6 ic50 = 0.012 uM 3U6 C20 H20 N6 S c1cc(nc(c1....
17 4N70 Ki = 0.001 nM 2HX C23 H22 F3 N5 O2 C[C@H]1CN(....
18 4WRS ic50 = 0.4 nM 3U1 C24 H21 F2 N5 O c1cc(c(c(c....
19 2XIX - XIX C2 H5 N5 c1([nH]nc(....
20 2J2I ic50 = 0.2 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
21 3VBQ ic50 = 470 pM 0F5 C20 H23 N5 O2 S c1cc(cc(c1....
22 2OBJ ic50 = 0.05 uM VRV C18 H11 Br N2 O2 c1ccc(cc1)....
23 2O3P ic50 = 1.1 uM QUE C15 H10 O7 c1cc(c(cc1....
24 3VBY ic50 = 28 uM 0FR C13 H9 N O2 c1ccc2c(c1....
25 2XIY - XIY C8 H8 N2 O c1ccc2c(c1....
26 4A7C ic50 = 0.006 uM E46 C18 H19 F3 N6 O c1cc(cc(c1....
27 3BGQ Ki = 11 nM VX2 C18 H18 F3 N5 c1cc(cc(c1....
28 3R02 ic50 = 0.001 uM UNM C15 H17 Br N2 O3 c1c2cc(oc2....
29 4K18 Ki = 1.1 nM 1OB C21 H14 F N5 O2 c1cc(ccc1C....
30 5DIA - 5E6 C22 H23 N7 c1cc(nc(c1....
31 5KZI ic50 = 0.07 nM 6YN C22 H21 F2 N7 c1cc(c(c(c....
32 2BIK - BI1 C25 H24 N4 O2 CN(C)CCCn1....
33 4BZN ic50 = 1.441 uM UGX C18 H23 N3 O2 S CC(C)(C)CN....
34 3VBV ic50 = 10 uM 0FK C10 H8 N2 O2 c1cc2ccc(n....
35 3UIX ic50 = 0.151 uM Q17 C17 H18 N4 O c1ccc2c(c1....
36 1YXV - LI6 C10 H9 N O3 CN1c2ccccc....
37 3UMW ic50 = 3 nM 596 C22 H22 N4 O3 COc1ccc2c(....
38 1YHS ic50 = 0.01 uM STU C28 H26 N4 O3 C[C@@]12[C....
39 2XJ1 Kd = 28 nM XJ1 C19 H22 N4 O2 c1cc(cc(c1....
40 2O64 Kd = 0.34 uM MYU C15 H10 O8 c1cc(c(cc1....
41 4ALW ic50 = 27 nM HY7 C16 H17 Br N4 O2 CN1CCN(CC1....
42 3BGZ Ki = 0.55 uM VX3 C21 H15 N O2 c1ccc(cc1)....
43 2O63 Kd = 0.78 uM MYC C15 H10 O8 c1c(cc(c(c....
44 5V82 Ki = 0.07 nM 96Y C21 H19 F2 N7 Cc1cncc(n1....
45 3VC4 ic50 = 24 nM 0FS C11 H6 F3 N O2 S c1cc(cc(c1....
46 5DHJ Ki = 0.2 uM 5E5 C12 H10 N4 Cc1c2cc(nc....
47 2XIZ - XIZ C8 H7 N O2 c1cnccc1C=....
48 1YI3 ic50 = 4 uM LY2 C19 H17 N O3 c1ccc(cc1)....
49 2XJ2 Kd = 66 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
50 1YI4 - ADN C10 H13 N5 O4 c1nc(c2c(n....
51 3R00 ic50 = 8.5 uM UNJ C9 H5 Br O3 c1cc2c(cc1....
52 3A99 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
53 3C4E ic50 ~ 100 uM C4E C13 H11 N3 c1ccc(cc1)....
54 3MA3 ic50 = 60 nM 01I C16 H8 O6 c1cc2c(cc(....
55 3VBX ic50 = 17 uM 0FO C9 H5 Br O3 c1cc2c(cc1....
56 5DGZ Ki = 14 nM L20 C24 H23 N5 O Cc1c2cc(cc....
57 2OI4 ic50 = 2.5 nM JM1 C23 H12 F N3 O3 Ru c1ccc2c(c1....
58 5EOL ic50 = 0.3 nM 5QO C21 H21 N5 O Cc1c2nc3c(....
59 3WE8 - RUI C18 H7 N2 O2 Ru c1cc2c3c4c....
60 3BWF ic50 = 0.6 nM DWC C23 H9 N3 O4 Os c1cc2c3c(c....
61 4WSY ic50 = 0.017 uM 3U5 C19 H13 N5 S c1ccc2c(c1....
62 4BZO ic50 = 0.013 uM 676 C22 H22 F N5 O2 c1ccc(cc1)....
63 5DWR Ki < 0.001 uM 5H7 C24 H23 F3 N4 O C[C@H]1C[C....
64 4XHK ic50 = 5 nM 3YR C19 H16 F2 N4 O2 S c1cc(c(c(c....
65 4K0Y Ki = 15 nM 1OA C18 H18 F N5 O2 c1cc(ccc1N....
66 4DTK ic50 < 0.004 uM 7LI C18 H23 N3 O3 S CC(C)Oc1cc....
67 4N6Z Ki = 16 nM 2HW C15 H19 N7 O c1cncc(c1N....
68 4AS0 - RPS C20 H19 N2 O3 Ru S3 c1c2c(cc3c....
50% Homology Family (69)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 55 families.
1 1XR1 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
2 4MBI - 26K C13 H17 N7 CN(C)CCNc1....
3 4MTA - 2D2 C12 H10 O3 Cc1c(cc(o1....
4 3VBT ic50 = 37 uM 0F9 C9 H7 Cl N2 O c1cc(c(cc1....
5 1YXX - LI7 C14 H10 N2 O2 c1ccc2c(c1....
6 5IIS Ki < 0.001 uM 6CB C23 H19 F N6 O Cc1cc(cc(n....
7 4K1B Ki = 0.003 nM 1OC C26 H24 F2 N8 O c1ccc(c(c1....
8 4XH6 ic50 = 2.71 uM HUL C16 H12 O6 COc1c(cc2c....
9 1YXU - AMP C10 H14 N5 O7 P c1nc(c2c(n....
10 1XWS - BI1 C25 H24 N4 O2 CN(C)CCCn1....
11 3R04 ic50 = 0.12 uM UNQ C19 H20 N4 O3 c1cc2c(cc1....
12 5IPJ ic50 = 0.3 nM 6CD C20 H23 N5 O2 C[C@@H]1c2....
13 2C3I Kd = 25 nM IYZ C18 H18 N4 O CC(=O)c1cc....
14 3VBW ic50 = 6 uM 0FN C10 H5 N O2 c1ccc2c(c1....
15 3F2A ic50 = 57 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
16 4WT6 ic50 = 0.012 uM 3U6 C20 H20 N6 S c1cc(nc(c1....
17 4N70 Ki = 0.001 nM 2HX C23 H22 F3 N5 O2 C[C@H]1CN(....
18 4WRS ic50 = 0.4 nM 3U1 C24 H21 F2 N5 O c1cc(c(c(c....
19 2XIX - XIX C2 H5 N5 c1([nH]nc(....
20 2J2I ic50 = 0.2 uM LY4 C28 H28 N4 O3 CN(C)C[C@@....
21 3VBQ ic50 = 470 pM 0F5 C20 H23 N5 O2 S c1cc(cc(c1....
22 2OBJ ic50 = 0.05 uM VRV C18 H11 Br N2 O2 c1ccc(cc1)....
23 2O3P ic50 = 1.1 uM QUE C15 H10 O7 c1cc(c(cc1....
24 3VBY ic50 = 28 uM 0FR C13 H9 N O2 c1ccc2c(c1....
25 2XIY - XIY C8 H8 N2 O c1ccc2c(c1....
26 4A7C ic50 = 0.006 uM E46 C18 H19 F3 N6 O c1cc(cc(c1....
27 3BGQ Ki = 11 nM VX2 C18 H18 F3 N5 c1cc(cc(c1....
28 3R02 ic50 = 0.001 uM UNM C15 H17 Br N2 O3 c1c2cc(oc2....
29 4K18 Ki = 1.1 nM 1OB C21 H14 F N5 O2 c1cc(ccc1C....
30 5DIA - 5E6 C22 H23 N7 c1cc(nc(c1....
31 5KZI ic50 = 0.07 nM 6YN C22 H21 F2 N7 c1cc(c(c(c....
32 2BIK - BI1 C25 H24 N4 O2 CN(C)CCCn1....
33 4BZN ic50 = 1.441 uM UGX C18 H23 N3 O2 S CC(C)(C)CN....
34 3VBV ic50 = 10 uM 0FK C10 H8 N2 O2 c1cc2ccc(n....
35 3UIX ic50 = 0.151 uM Q17 C17 H18 N4 O c1ccc2c(c1....
36 1YXV - LI6 C10 H9 N O3 CN1c2ccccc....
37 3UMW ic50 = 3 nM 596 C22 H22 N4 O3 COc1ccc2c(....
38 1YHS ic50 = 0.01 uM STU C28 H26 N4 O3 C[C@@]12[C....
39 2XJ1 Kd = 28 nM XJ1 C19 H22 N4 O2 c1cc(cc(c1....
40 2O64 Kd = 0.34 uM MYU C15 H10 O8 c1cc(c(cc1....
41 4ALW ic50 = 27 nM HY7 C16 H17 Br N4 O2 CN1CCN(CC1....
42 3BGZ Ki = 0.55 uM VX3 C21 H15 N O2 c1ccc(cc1)....
43 2O63 Kd = 0.78 uM MYC C15 H10 O8 c1c(cc(c(c....
44 5V82 Ki = 0.07 nM 96Y C21 H19 F2 N7 Cc1cncc(n1....
45 3VC4 ic50 = 24 nM 0FS C11 H6 F3 N O2 S c1cc(cc(c1....
46 5DHJ Ki = 0.2 uM 5E5 C12 H10 N4 Cc1c2cc(nc....
47 2XIZ - XIZ C8 H7 N O2 c1cnccc1C=....
48 1YI3 ic50 = 4 uM LY2 C19 H17 N O3 c1ccc(cc1)....
49 2XJ2 Kd = 66 nM 985 C19 H22 N4 O2 C[N@]1CCCN....
50 1YI4 - ADN C10 H13 N5 O4 c1nc(c2c(n....
51 3R00 ic50 = 8.5 uM UNJ C9 H5 Br O3 c1cc2c(cc1....
52 3A99 - ANP C10 H17 N6 O12 P3 c1nc(c2c(n....
53 3C4E ic50 ~ 100 uM C4E C13 H11 N3 c1ccc(cc1)....
54 3MA3 ic50 = 60 nM 01I C16 H8 O6 c1cc2c(cc(....
55 3VBX ic50 = 17 uM 0FO C9 H5 Br O3 c1cc2c(cc1....
56 5DGZ Ki = 14 nM L20 C24 H23 N5 O Cc1c2cc(cc....
57 2OI4 ic50 = 2.5 nM JM1 C23 H12 F N3 O3 Ru c1ccc2c(c1....
58 5EOL ic50 = 0.3 nM 5QO C21 H21 N5 O Cc1c2nc3c(....
59 3WE8 - RUI C18 H7 N2 O2 Ru c1cc2c3c4c....
60 3BWF ic50 = 0.6 nM DWC C23 H9 N3 O4 Os c1cc2c3c(c....
61 4WSY ic50 = 0.017 uM 3U5 C19 H13 N5 S c1ccc2c(c1....
62 4BZO ic50 = 0.013 uM 676 C22 H22 F N5 O2 c1ccc(cc1)....
63 5DWR Ki < 0.001 uM 5H7 C24 H23 F3 N4 O C[C@H]1C[C....
64 4XHK ic50 = 5 nM 3YR C19 H16 F2 N4 O2 S c1cc(c(c(c....
65 4K0Y Ki = 15 nM 1OA C18 H18 F N5 O2 c1cc(ccc1N....
66 4DTK ic50 < 0.004 uM 7LI C18 H23 N3 O3 S CC(C)Oc1cc....
67 4N6Z Ki = 16 nM 2HW C15 H19 N7 O c1cncc(c1N....
68 4AS0 - RPS C20 H19 N2 O3 Ru S3 c1c2c(cc3c....
69 4X7Q ic50 = 14 nM 3YR C19 H16 F2 N4 O2 S c1cc(c(c(c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ANP; Similar ligands found: 358
No: Ligand ECFP6 Tc MDL keys Tc
1 ANP 1 1
2 A2D 0.810811 0.945205
3 B4P 0.802632 0.945205
4 ADP 0.802632 0.972222
5 AP5 0.802632 0.945205
6 BA3 0.789474 0.945205
7 AU1 0.782051 1
8 ATP 0.772152 0.972222
9 AN2 0.769231 0.986111
10 AQP 0.7625 0.972222
11 5FA 0.7625 0.972222
12 M33 0.759494 0.932432
13 MAP 0.752941 0.972973
14 ACP 0.75 0.945946
15 APR 0.740741 0.945205
16 AR6 0.740741 0.945205
17 ACQ 0.73494 0.945946
18 AD9 0.731707 0.945946
19 SAP 0.731707 0.921053
20 AGS 0.731707 0.921053
21 AMP 0.723684 0.944444
22 A 0.723684 0.944444
23 ATF 0.717647 0.933333
24 ADX 0.716049 0.851852
25 CA0 0.716049 0.92
26 50T 0.707317 0.932432
27 PRX 0.698795 0.87013
28 ABM 0.696203 0.893333
29 AMP MG 0.683544 0.868421
30 AP2 0.679012 0.933333
31 A12 0.679012 0.933333
32 APC 0.678571 0.933333
33 TAT 0.674419 0.933333
34 A22 0.674157 0.958904
35 SRA 0.670886 0.894737
36 SRP 0.670455 0.883117
37 5AL 0.666667 0.906667
38 ADQ 0.659341 0.92
39 A1R 0.659341 0.884615
40 ADP MG 0.654762 0.881579
41 3OD 0.648936 0.92
42 BIS 0.648936 0.909091
43 5SV 0.648352 0.82716
44 BEF ADP 0.647059 0.858974
45 ADP BEF 0.647059 0.858974
46 OAD 0.645161 0.92
47 25L 0.642105 0.958904
48 AMO 0.641304 0.907895
49 G5P 0.636364 0.897436
50 DLL 0.634409 0.906667
51 AHX 0.634409 0.897436
52 00A 0.634409 0.860759
53 ANP MG 0.633333 0.921053
54 ADV 0.632184 0.907895
55 ADP PO3 0.632184 0.917808
56 RBY 0.632184 0.907895
57 NB8 0.631579 0.897436
58 25A 0.630435 0.945205
59 8QN 0.630435 0.906667
60 OOB 0.630435 0.906667
61 G3A 0.626263 0.897436
62 ATP MG 0.625 0.881579
63 4AD 0.623656 0.896104
64 PAJ 0.623656 0.8625
65 LAD 0.621053 0.839506
66 1ZZ 0.614583 0.819277
67 TXA 0.614583 0.907895
68 ME8 0.614583 0.819277
69 GTA 0.613861 0.864198
70 3UK 0.610526 0.894737
71 SON 0.604651 0.907895
72 ADP ALF 0.604396 0.848101
73 ALF ADP 0.604396 0.848101
74 WAQ 0.604167 0.860759
75 PR8 0.604167 0.829268
76 4UV 0.6 0.871795
77 GAP 0.6 0.87013
78 FYA 0.597938 0.881579
79 PTJ 0.597938 0.873418
80 ADP VO4 0.597826 0.906667
81 VO4 ADP 0.597826 0.906667
82 UP5 0.596154 0.896104
83 YAP 0.59596 0.871795
84 FA5 0.59596 0.883117
85 PAP 0.595506 0.958333
86 A4P 0.59434 0.823529
87 XAH 0.59 0.841463
88 4UU 0.588235 0.871795
89 AFH 0.588235 0.8625
90 9SN 0.585859 0.85
91 2A5 0.58427 0.894737
92 T5A 0.583333 0.821429
93 NAI 0.580952 0.884615
94 ITT 0.579545 0.917808
95 ATR 0.577778 0.944444
96 OMR 0.575472 0.831325
97 5AS 0.574713 0.781609
98 YLP 0.571429 0.8
99 48N 0.571429 0.873418
100 AP0 0.570093 0.873418
101 4TC 0.570093 0.873418
102 7D3 0.569767 0.881579
103 ADJ 0.568807 0.831325
104 GNP 0.568421 0.922078
105 DAL AMP 0.568421 0.881579
106 NXX 0.566038 0.907895
107 TXD 0.566038 0.884615
108 NAX 0.566038 0.851852
109 4UW 0.566038 0.839506
110 6V0 0.566038 0.873418
111 DND 0.566038 0.907895
112 XYA 0.565789 0.821918
113 ADN 0.565789 0.821918
114 RAB 0.565789 0.821918
115 AOC 0.564706 0.8
116 7D4 0.561798 0.881579
117 ADP BMA 0.561224 0.894737
118 TXE 0.560748 0.884615
119 TYM 0.560748 0.883117
120 YLB 0.555556 0.8
121 YLC 0.555556 0.819277
122 139 0.554545 0.851852
123 5N5 0.551282 0.797297
124 JB6 0.55 0.860759
125 LAQ 0.54717 0.819277
126 MYR AMP 0.544554 0.797619
127 A4D 0.544304 0.797297
128 5CD 0.544304 0.783784
129 7MD 0.542857 0.864198
130 6AD 0.542553 0.886076
131 A2R 0.541667 0.958904
132 UPA 0.541284 0.884615
133 YLA 0.540541 0.8
134 A A 0.54 0.918919
135 COD 0.539823 0.793103
136 BTX 0.539823 0.821429
137 G5A 0.537634 0.781609
138 CNA 0.535714 0.907895
139 AYB 0.535714 0.790698
140 3DH 0.535714 0.753247
141 BT5 0.535088 0.811765
142 ATP A A A 0.533981 0.905405
143 IOT 0.531532 0.811765
144 MTA 0.53012 0.753247
145 3AM 0.529412 0.90411
146 A3P 0.52809 0.944444
147 NAD 0.526316 0.906667
148 PPS 0.526316 0.851852
149 EP4 0.52439 0.734177
150 7D5 0.52381 0.855263
151 AMP DBH 0.52381 0.87013
152 J7C 0.522727 0.75
153 A5A 0.520833 0.809524
154 EAD 0.520661 0.851852
155 TSB 0.520408 0.821429
156 AHZ 0.518519 0.797619
157 M2T 0.518072 0.716049
158 DTA 0.518072 0.766234
159 A3D 0.517241 0.894737
160 6RE 0.517241 0.740741
161 YLY 0.516949 0.790698
162 SSA 0.515464 0.802326
163 NA7 0.514852 0.933333
164 TYR AMP 0.514286 0.858974
165 AR6 AR6 0.514019 0.893333
166 7MC 0.513514 0.843373
167 A2P 0.511111 0.930556
168 52H 0.510204 0.781609
169 VMS 0.510204 0.790698
170 54H 0.510204 0.790698
171 TAD 0.509259 0.8625
172 NAQ 0.508333 0.85
173 A3N 0.505618 0.766234
174 AV2 0.505155 0.893333
175 5CA 0.50505 0.802326
176 53H 0.50505 0.781609
177 ARU 0.504951 0.839506
178 ARG AMP 0.504587 0.809524
179 ZID 0.504132 0.894737
180 P1H 0.504 0.831325
181 3AT 0.5 0.945205
182 NAE 0.5 0.871795
183 AVV 0.5 0.873418
184 P5A 0.495146 0.747253
185 DSZ 0.49505 0.802326
186 LSS 0.49505 0.764045
187 NSS 0.49505 0.802326
188 N0B 0.491803 0.8
189 AF3 ADP 3PG 0.491071 0.817073
190 LA8 ALF 3PG 0.491071 0.817073
191 ALF ADP 3PG 0.491071 0.817073
192 NVA LMS 0.490196 0.764045
193 DAT 0.489362 0.881579
194 IMO 0.488889 0.90411
195 ZAS 0.488636 0.792208
196 FDA 0.488372 0.813953
197 NAJ PZO 0.487395 0.85
198 4TA 0.487179 0.788235
199 LPA AMP 0.486486 0.797619
200 LEU LMS 0.485437 0.764045
201 DTP 0.484536 0.881579
202 V3L 0.484536 0.945205
203 GJV 0.483516 0.731707
204 S4M 0.483516 0.651685
205 DZD 0.483051 0.8625
206 2AM 0.482759 0.917808
207 5AD 0.481013 0.726027
208 KAA 0.480769 0.755556
209 GSU 0.480769 0.781609
210 NDE 0.480315 0.907895
211 M24 0.479339 0.851852
212 MAO 0.478261 0.761905
213 DSH 0.477778 0.707317
214 NEC 0.477778 0.727273
215 FAD 0.477273 0.831325
216 FAS 0.477273 0.831325
217 RGT 0.476636 0.933333
218 0WD 0.474576 0.897436
219 G A A A 0.474576 0.85
220 FNK 0.474074 0.786517
221 5X8 0.473684 0.74359
222 6FA 0.473282 0.821429
223 FB0 0.472868 0.786517
224 NDC 0.472868 0.85
225 YSA 0.472222 0.781609
226 7DD 0.468085 0.958333
227 OVE 0.466667 0.881579
228 NAD IBO 0.466102 0.848101
229 MHZ 0.463158 0.701149
230 A3G 0.461538 0.779221
231 6C6 0.459184 0.858974
232 U A G G 0.458333 0.860759
233 SFG 0.458333 0.730769
234 7D7 0.45679 0.723684
235 128 0.45614 0.8
236 SFD 0.455224 0.736842
237 DDS 0.454545 0.855263
238 GDP 0.454545 0.896104
239 6IA 0.454545 0.817073
240 NJP 0.453782 0.921053
241 ODP 0.453782 0.886076
242 7DT 0.453608 0.958333
243 A7D 0.452632 0.75641
244 Z5A 0.452381 0.802326
245 WSA 0.452174 0.790698
246 7C5 0.45045 0.797468
247 FAY 0.449275 0.841463
248 NDP 0.449153 0.897436
249 A5D 0.44898 0.766234
250 SA8 0.44898 0.690476
251 NAJ PYZ 0.448 0.851852
252 71V 0.446809 0.884615
253 GGZ 0.446602 0.804878
254 RFL 0.446043 0.802326
255 2SA 0.445545 0.907895
256 AMP NAD 0.444444 0.858974
257 GP3 0.444444 0.897436
258 SAI 0.444444 0.716049
259 SAH 0.444444 0.725
260 A A A 0.443396 0.881579
261 PO4 PO4 A A A A PO4 0.443396 0.878378
262 4YB 0.442478 0.764045
263 GTP 0.441176 0.896104
264 SMM 0.441176 0.670455
265 S7M 0.441176 0.674419
266 Y3J 0.440476 0.706667
267 SAM 0.44 0.674419
268 649 0.439655 0.747253
269 12D 0.438596 0.809524
270 A3S 0.4375 0.789474
271 NPW 0.436975 0.864198
272 GCP 0.436893 0.873418
273 AAT 0.435644 0.690476
274 EEM 0.435644 0.674419
275 GNH 0.435644 0.909091
276 DCA 0.435484 0.804598
277 ETB 0.435484 0.813953
278 N6P 0.433962 0.890411
279 TXP 0.433333 0.897436
280 NZQ 0.433333 0.886076
281 PGS 0.43299 0.860759
282 APU 0.432203 0.871795
283 PUA 0.432 0.8625
284 62F 0.431655 0.841463
285 F2N 0.431507 0.795455
286 DA 0.430108 0.855263
287 D5M 0.430108 0.855263
288 J7V 0.429688 0.813953
289 NIA 0.428571 0.848101
290 6K6 0.428571 0.905405
291 A3T 0.428571 0.8
292 0T1 0.428571 0.804598
293 COA 0.428571 0.804598
294 P5F 0.427586 0.804598
295 AAM 0.425532 0.944444
296 0UM 0.424528 0.682353
297 G1R 0.423077 0.884615
298 AMZ 0.422222 0.891892
299 C2R 0.422222 0.88
300 A U 0.420168 0.848101
301 IDP 0.42 0.894737
302 GSP 0.419048 0.851852
303 COS 0.418605 0.786517
304 CAO 0.418605 0.777778
305 AMX 0.418605 0.813953
306 30N 0.418605 0.736842
307 DG1 0.418605 0.897436
308 1DG 0.418605 0.897436
309 TM1 0.418182 0.797619
310 A6D 0.416667 0.746988
311 K15 0.416667 0.666667
312 V1N 0.415929 0.893333
313 SCO 0.415385 0.804598
314 CMX 0.415385 0.804598
315 GEK 0.415094 0.719512
316 NHD 0.414634 0.881579
317 XNP 0.414634 0.851852
318 AIR 0.413793 0.876712
319 COK 0.413534 0.786517
320 G2R 0.412844 0.8625
321 FCX 0.412214 0.777778
322 FAM 0.412214 0.786517
323 ACO 0.412214 0.777778
324 NAP 0.410853 0.92
325 CNV FAD 0.409722 0.775281
326 FA9 0.409396 0.843373
327 SXZ 0.409091 0.694118
328 HAX 0.409091 0.806818
329 PLP AAD 0.408 0.744444
330 TAP 0.407692 0.884615
331 2MC 0.407407 0.752688
332 62X 0.407407 0.651685
333 GKE 0.40708 0.8625
334 GDD 0.40708 0.8625
335 GDC 0.40708 0.8625
336 FYN 0.406015 0.804598
337 3KK 0.406015 0.786517
338 U G A 0.405797 0.819277
339 NA0 0.40458 0.907895
340 101 0.404255 0.855263
341 G 0.40404 0.883117
342 5GP 0.40404 0.883117
343 MGP 0.403846 0.8625
344 MCD 0.402985 0.786517
345 OXK 0.402985 0.786517
346 CA6 0.402985 0.714286
347 SOP 0.402985 0.786517
348 3AD 0.402299 0.783784
349 S8M 0.401869 0.78481
350 YE1 0.40146 0.795455
351 1VU 0.4 0.777778
352 2VA 0.4 0.779221
353 CMC 0.4 0.786517
354 7RP 0.4 0.902778
355 GMV 0.4 0.873418
356 6G0 0.4 0.8625
357 CO6 0.4 0.786517
358 NMX 0.4 0.782609
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4N70; Ligand: 2HX; Similar sites found: 312
This union binding pocket(no: 1) in the query (biounit: 4n70.bio1) has 46 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 5TPU TYD 0.02702 0.43064 None
2 1D8C GLV 0.04231 0.41328 1.52439
3 2DQA NAG NAG NAG 0.03851 0.41142 1.6129
4 2IF8 ADP 0.00028 0.53759 1.82927
5 3K5I ADP 0.004437 0.43755 1.82927
6 4RDL FUC GAL NDG FUC 0.004577 0.4745 1.94805
7 3LHS SF8 0.02879 0.42603 2.02703
8 2AQX ATP 0.00177 0.45249 2.07612
9 3X01 AMP 0.0007082 0.51841 2.13415
10 3ORQ ADP 0.001232 0.46348 2.13415
11 5JDA AMP 0.04847 0.40233 2.13415
12 4FE2 AIR 0.01161 0.43918 2.35294
13 4FE2 ADP 0.01503 0.42933 2.35294
14 1PK8 ATP 0.0008149 0.457 2.36967
15 4ZGP ADP 0.00215 0.46403 2.38908
16 4B1L FRU 0.03925 0.40487 2.42424
17 2YW2 ATP 0.003081 0.44493 2.43902
18 2ZWS PLM 0.04305 0.43659 2.43902
19 4C2C ALA ALA ALA 0.03642 0.42253 2.43902
20 3SJK LYS PRO VAL LEU ARG THR ALA 0.007859 0.45986 2.63158
21 3TM0 ANP 0.0001498 0.46747 2.6616
22 3TM0 B31 0.0001882 0.46047 2.6616
23 2PUL ACP 0.00001707 0.56772 2.7439
24 5DZT AMP 0.0004718 0.527 2.7439
25 1EHI ADP 0.001618 0.46182 2.7439
26 1I7L ATP 0.0007886 0.46111 2.7439
27 2IO8 ADP 0.001317 0.4513 2.7439
28 4ZWP M44 0.04627 0.41442 2.7439
29 3R4S SLB 0.04514 0.40685 2.7439
30 3QRC SCR 0.01386 0.4424 3.18471
31 4IAW LIZ 0.04952 0.40903 3.19149
32 1A8U BEZ 0.03844 0.41659 3.2491
33 1K4M CIT 0.04161 0.42094 3.28639
34 5I35 ANP 0.00000169 0.6173 3.35366
35 3VOT ADP 0.0009455 0.49668 3.35366
36 1HFU NAG NDG 0.01153 0.4691 3.35366
37 3TII ANP 0.003695 0.46546 3.35366
38 2Z9I GLY ALA THR VAL 0.02897 0.43153 3.39506
39 1ZP9 ATP 0.000003621 0.60822 3.48837
40 2VQD AP2 0.0007065 0.47471 3.65854
41 3KAL ADP 0.001504 0.42555 3.65854
42 4OCJ NDG 0.00006939 0.41902 3.65854
43 5JM8 ATP 0.009612 0.41885 3.65854
44 4EIL CB3 0.0459 0.40732 3.65854
45 4OCV ANP 0.00002807 0.54534 3.96341
46 3V4S ATP 0.002786 0.44348 3.96341
47 3HQP OXL 0.02253 0.41032 3.96341
48 4K37 SAM 0.02648 0.40993 3.96341
49 4K38 SAM 0.02572 0.40459 3.96341
50 4OAS 2SW 0.02692 0.41278 4.16667
51 2GQS ADP 0.007503 0.43717 4.21941
52 5C1P ADP 0.004606 0.45591 4.24837
53 3VPC ADP 0.0003792 0.48306 4.25532
54 4UYW H1S 0.0015 0.54939 4.26829
55 5NCY 8TK 0.0001089 0.47973 4.26829
56 3E7S AT2 0.03894 0.41913 4.26829
57 4XMF HSM 0.0004735 0.53025 4.34783
58 3ZJX BOG 0.004259 0.47509 4.49827
59 4XBT 3ZQ 0.01206 0.42355 4.51613
60 4XBT FLC 0.01307 0.42186 4.51613
61 4GYI ADP 0.00001017 0.59279 4.57317
62 2X3J ATP 0.01745 0.40974 4.57317
63 3A6T 8OG 0.01795 0.41836 4.65116
64 3HAV ATP 0.0002134 0.54628 4.68227
65 3DNT ATP 0.0003717 0.47551 4.77273
66 4PU5 ANP 0.0003856 0.47868 4.87805
67 4ZS4 ATP 0.00003222 0.5425 4.88599
68 1IA9 ANP 0.000157 0.50988 5
69 4CC6 L5Y 0.001891 0.48608 5.03145
70 2YRX AMP 0.02653 0.42754 5.09978
71 4R78 AMP 0.000002376 0.64256 5.17799
72 2PYW ADP 0.000004046 0.57904 5.18293
73 2Q7D ANP 0.00266 0.43177 5.18293
74 3CV2 OXL 0.02384 0.42904 5.18293
75 4YRD 3IT 0.0277 0.4265 5.18293
76 1FWV SGA MAG FUC 0.005583 0.45992 5.22388
77 3VPB ADP 0.0002234 0.48134 5.35714
78 1U18 HSM 0.008799 0.42134 5.40541
79 3PDT ADP 0.00007538 0.54176 5.45455
80 1LOP SIN ALA PRO ALA NIT 0.03116 0.42455 5.4878
81 5C4L 4XR 0.00002434 0.41746 5.60748
82 1TQP ATP 0.000001279 0.58404 5.67376
83 5CAD PCA 0.03918 0.41259 5.79268
84 5T7I LAT NAG GAL 0.04506 0.4164 5.80645
85 5MG2 7M8 0.04408 0.41182 5.83942
86 4O4F ATP 0.001004 0.45307 6.04839
87 4O4F IHP 0.001113 0.44788 6.04839
88 4U98 ACP 0.0006859 0.48853 6.09756
89 5MRH Q9Z 0.01361 0.4397 6.09756
90 5FJJ MAN 0.01062 0.4202 6.09756
91 4LH7 1X8 0.001242 0.49977 6.19195
92 5T96 79J 0.02424 0.43556 6.40244
93 4WW7 AMP 0.0000001187 0.43222 6.51341
94 5MY8 RXZ 0.000001318 0.57785 6.70732
95 3I0O ADP 0.0002316 0.52888 6.70732
96 4UWH JXM 0.000419 0.5042 6.70732
97 3W0O ADP 0.00003085 0.50193 6.70732
98 3W0O HY0 0.00003085 0.50193 6.70732
99 3I0O SMI 0.04054 0.42034 6.70732
100 1QY1 PRZ 0.01946 0.40476 6.89655
101 5NBW 8SK 0.04666 0.40363 7.20721
102 4D4U FUC NDG GAL FUC 0.04545 0.41093 7.30159
103 3CTL S6P 0.02053 0.40929 7.35931
104 5O4F 8VE 0.03619 0.41653 7.36434
105 2CFM AMP 0.0009744 0.49599 7.92683
106 5DXT 5H5 0.006362 0.43357 7.92683
107 3UYW TAU 0.01583 0.4371 7.94393
108 3WVR AMP 0.0007333 0.49194 8.23171
109 4DFU QUE 0.002717 0.48301 8.38509
110 4XYM A12 0.0008162 0.47592 8.53659
111 5GZK BGC 0.02327 0.406 8.53659
112 5HWC FK5 0.04308 0.41237 8.69565
113 1PVC ILE SER GLU VAL 0.04905 0.42284 8.82353
114 4K55 H6P 0.02062 0.42999 8.87097
115 1GUX ASP LEU TYR CYS TYR GLU GLN LEU ASN 0.03085 0.4066 9.21053
116 4OAV ACP 0.0000003263 0.65256 9.45122
117 5GZ9 ANP 0.0000005922 0.42897 9.83607
118 2BKK ADP 0.00002172 0.57581 10.0592
119 4RYV ZEA 0.03065 0.41674 10.3226
120 4ANW O92 0.00006516 0.48168 10.9756
121 1RGE 2GP 0.04941 0.41366 11.4583
122 1RNT 2GP 0.01939 0.41048 11.5385
123 3TDV GDP 0.000003823 0.59293 12.4183
124 3H9R TAK 0.0001112 0.55247 12.5
125 4NS0 PIO 0.01295 0.44691 12.782
126 2QLU ADE 0.0008328 0.50162 13.0573
127 1VJY 460 0.00000003239 0.61144 13.5314
128 1LNX URI 0.04315 0.41778 13.5802
129 4Z4P SAH 0.038 0.40206 14.4578
130 4Q5H ANP 0.0000002462 0.65055 14.4737
131 4AZT LY2 0.001295 0.48947 14.6341
132 3E8N ATP 0.000001411 0.50505 14.939
133 3E8N VRA 0.000001411 0.50505 14.939
134 5CKW ANP 0.000003398 0.62549 15.2439
135 5KBE IPH 0.03207 0.4234 15.2838
136 4O1P ANP 0.0000006253 0.40406 16.7683
137 3GNI ATP 0.000003571 0.58156 17.6829
138 3KMW ATP 0.0006549 0.48952 18.0812
139 1TZD ADP 0.0006359 0.51474 18.1818
140 5W2I ADP 0.000667 0.46432 18.677
141 5W2I I3P 0.000667 0.46432 18.677
142 4BKJ STI 0.0005568 0.46416 19.3651
143 4Y85 499 0.00001852 0.56597 19.8171
144 1W2D ADP 0.004253 0.46224 20
145 1W2D 4IP 0.002769 0.42542 20
146 5USZ SKE 0.0000002702 0.59609 20.0692
147 5C03 AGS 0.000001187 0.61751 20.122
148 4YZC STU 0.0000001628 0.49094 20.4268
149 3LQV ADE 0.01618 0.43282 20.5128
150 4WOV 3SM 0.00002914 0.56924 20.8202
151 5VC5 96M 0.000002946 0.42926 21.1073
152 4K33 ACP 0.00000008975 0.42934 21.8462
153 1Y57 MPZ 0.0000002505 0.62162 21.9512
154 2H8H H8H 0.000002442 0.60235 21.9512
155 4AT3 LTI 0.000149 0.47422 22.0736
156 2X2M X2M 0.0000003096 0.42847 22.6115
157 3RI1 3RH 0.0000000359 0.47623 22.6837
158 5UR1 YY9 0.00003314 0.43934 23.1511
159 3LXN MI1 0.0000001277 0.64887 23.2704
160 4IX4 ADP 0.0000002973 0.42127 23.4756
161 2XVD AS6 0.000003925 0.54275 23.5099
162 5JKG 6LF 0.00008883 0.41489 23.7942
163 3I7V B4P 0.005936 0.44549 23.8806
164 3SLS ANP 0.000000186 0.6342 24.0132
165 3SLS 77D 0.01206 0.42356 24.0132
166 4E1Z 0MX 0.0000003294 0.61629 24.3986
167 4GJ3 0XP 0.00000008081 0.60112 24.5033
168 5IQD RIO 0.000004243 0.45486 24.918
169 5IQD GNP 0.000003618 0.45371 24.918
170 4XH0 ADP 0.00001377 0.61369 25
171 3G5D 1N1 0.00000006923 0.54616 25.1748
172 4YMJ 4EJ 0.000000919 0.68177 25.3289
173 5T8O 76Z 0.00000002548 0.68144 25.6098
174 3ALN ANP 0.0000006589 0.61571 25.6881
175 4AG8 AXI 0.00002378 0.48826 25.9494
176 3VRY B43 0.00005253 0.50856 26.2195
177 4IDT T28 0.0000001187 0.67423 26.5244
178 2CSN CKI 0.000176 0.43576 26.936
179 5LXC 7AA 0.000000009569 0.42323 27.439
180 5HX8 66P 0.00000112 0.57548 27.4834
181 2F57 23D 0.00001113 0.58363 28.0757
182 5AWM ANP 0.000005 0.61664 28.3537
183 3GC0 AMP 0.000001286 0.63905 29.2683
184 5LI9 ACP 0.000001115 0.61178 29.2683
185 5LI1 ANP 0.00000002487 0.45069 29.2683
186 4BTK DTQ 0.0000001023 0.4286 29.2683
187 4H3P ANP 0.000000004715 0.73364 29.5732
188 5LPZ ADP 0.000000006649 0.72642 29.5732
189 5BYZ 4WE 0.00000009471 0.59837 29.5732
190 4WHZ 3NL 0.000005274 0.47699 29.5732
191 4H3Q ANP 0.0000000254 0.46164 29.5732
192 2WU6 DKI 0.000000008834 0.68677 29.878
193 5BVE 4VG 0.0000003027 0.47143 29.878
194 4AUA 4AU 0.0000007709 0.63413 29.9674
195 3PVW QRX 0.000001344 0.5721 30.1829
196 4YLL 4E3 0.000000245 0.44297 30.1829
197 5UKL SIX 0.00002426 0.40841 30.1829
198 3UIM ANP 0.00000004351 0.68696 30.3681
199 4FL3 ANP 0.0000000165 0.68223 30.4878
200 3GC8 B45 0.000001058 0.59972 30.4878
201 1CM8 ANP 0.0000004141 0.40829 30.4878
202 3KRR DQX 0.0000001388 0.54467 30.5085
203 5X8I SQZ 0.0000000021 0.75063 31.0976
204 4QTB 38Z 0.00000005504 0.47943 31.0976
205 5HCY 60D 0.00000003139 0.56463 31.4024
206 3VHE 42Q 0.000005867 0.53115 31.4763
207 4NST ADP 0.0000008256 0.62513 31.7073
208 4NST AF3 0.000001572 0.54902 31.7073
209 3C1X CKK 0.0002649 0.49017 31.7073
210 2HK5 1BM 0.0000004924 0.41568 31.8519
211 2JLD AG1 0.0000000001241 0.69958 32.0122
212 4CRL C1I 0.0000003652 0.56539 32.0122
213 5LXT ACP 0.001995 0.44666 32.1678
214 4E93 GUI 0.0000001581 0.58439 32.622
215 5LPB ADP 0.00000184 0.63951 32.7703
216 5HQ0 LZ9 0.00000004148 0.67159 32.7815
217 1U5R ATP 0.00000008029 0.67409 32.9268
218 5EFQ ADP 0.0000002635 0.64912 32.9268
219 3PP0 03Q 0.0000116 0.53226 32.9268
220 1OUK 084 0.00001004 0.50588 32.9268
221 4CLI 5P8 0.000002556 0.47657 33.3333
222 3LXK MI1 0.0000005912 0.58186 33.6391
223 4AU8 Z3R 0.000004255 0.62034 33.7838
224 2OO8 RAJ 0.0008298 0.46752 34.0694
225 5JFS 6K0 0.00001953 0.43911 34.0909
226 1UNH IXM 0.0000002102 0.67957 34.2466
227 3O0G 3O0 0.00000002049 0.42785 34.2466
228 1V0O INR 0.0000001429 0.65411 35.0694
229 3GQI ACP 0.00000001713 0.70654 35.2761
230 5TA6 79D 0.000002193 0.55803 35.3659
231 3TXO 07U 0.000000003917 0.43025 35.3659
232 5HES 032 0.000003438 0.40047 35.5049
233 3TTI KBI 0.00000005664 0.6245 35.6707
234 4Y93 746 0.000005771 0.55009 35.6707
235 5U6C 7YS 0.0000005739 0.61185 35.873
236 2BPM 529 0.0000000004513 0.60823 35.9223
237 1OPK P16 0.00011 0.47609 35.9756
238 3SRV S19 0.000000005421 0.43385 36.1011
239 4UX9 ANP 0.0000000273 0.68004 36.2805
240 4IZY 1J2 0.000000217 0.63815 36.2805
241 3KRL KRL 0.000007114 0.56192 36.2805
242 4CFU 2WC 0.00000000946 0.73842 36.3036
243 4BCM T7Z 0.000001476 0.66349 36.5448
244 3BU5 ATP 0.0000000186 0.43644 36.6013
245 4F4P 0SB 0.00000006754 0.55038 36.63
246 4BCN T9N 0.000000009942 0.74784 36.6667
247 5EOB 5QQ 0.0001016 0.44077 36.6771
248 5KO1 6UY 0.000005562 0.59176 36.7491
249 4QMN DB8 0.0000003213 0.55845 36.7742
250 3EKK GS2 0.000001765 0.52672 36.8078
251 5JGA 6KC 0.0000002759 0.5749 36.8254
252 5LMK 6ZK 0.0000001138 0.40467 37.037
253 1XJD STU 0.000000002772 0.73531 37.1951
254 3E7O 35F 0.00002276 0.49962 37.1951
255 2XMY CDK 0.00000258 0.50292 37.2483
256 1PHK ATP 0.000000002934 0.45922 37.2483
257 2B9I ADP 0.0000002428 0.65084 37.3938
258 2B9J ADP 0.0000004178 0.64726 37.3938
259 2B9H ADP 0.0000001048 0.43399 37.3938
260 3NW7 LGV 0.0001523 0.42579 37.4593
261 4P5Z Q7M 0.00001622 0.48774 37.5
262 2V7O DRN 0.000000005184 0.40211 37.5
263 2B9F ADP 0.000000344 0.4177 37.6771
264 5NKB 8ZT 0.000004441 0.49793 37.9085
265 3PLS ANP 0.00000002315 0.70928 37.9195
266 3IGO ANP 0.0000008322 0.60448 38.1098
267 1K3A ACP 0.000001236 0.63995 38.1271
268 4U0I 0LI 0.0002469 0.46209 38.4127
269 3F7Z 34O 0.000000001283 0.45733 38.4146
270 3ZRM ZRM 0.0000002016 0.41763 38.4146
271 3HMO STU 0.0000001627 0.66747 38.7195
272 4NM5 ADP 0.0000006393 0.60337 38.7195
273 4WB7 ATP 0.0000002848 0.56042 38.7195
274 4WB6 ATP 0.00000001076 0.48077 38.7195
275 4WNK 453 0.0000001655 0.59396 39.0244
276 4OTH DRN 0.000000000769 0.74305 39.3293
277 2PVF ACP 0.00000001608 0.71709 39.3293
278 1U59 STU 0.00000001924 0.7041 39.3728
279 1JPA ANP 0.00004688 0.57289 39.7436
280 4KBA 1QM 0.000001588 0.56389 39.8792
281 4I6H 1C8 0.0001835 0.51161 39.9351
282 5N87 N66 0.0000009914 0.54007 40.2556
283 2A19 ANP 0.0000002823 0.68241 40.493
284 2GU8 796 0.000000007653 0.53627 40.5488
285 2Y6O 1N1 0.000002965 0.57928 40.8935
286 1BYG STU 0.0000005714 0.64864 41.0072
287 4EWH T77 0.0000002139 0.60034 41.0909
288 3IDB ANP 0.000000008723 0.68701 41.1585
289 1RE8 BD2 0.0000000001502 0.61581 41.1585
290 3SXF BK5 0.00001257 0.50224 41.1585
291 2QCS ANP 0.000000006669 0.4857 41.1585
292 3FHI ANP 0.00000001239 0.48093 41.1585
293 2VZ6 FEF 0.000001962 0.6296 41.2141
294 4ASE AV9 0.00004592 0.50272 41.7683
295 4FG8 ATP 0.0000002718 0.42938 41.9048
296 5H2U 1N1 0.0004238 0.49402 41.9476
297 4BHN BH9 0.0000001997 0.63983 42.0732
298 5DA3 58V 0.00001407 0.59297 42.2642
299 4L9I 8PR 0.00003399 0.55295 42.378
300 5TO8 7FM 0.000008357 0.49485 42.5532
301 3SXS PP2 0.00001723 0.54976 42.9104
302 2OFV 242 0.00001261 0.49861 42.9603
303 4XLI 1N1 0.000001301 0.62291 43.2836
304 2WEI VGG 0.00003385 0.55929 43.554
305 3HZT J60 0.000001392 0.64591 43.5976
306 4CSV STI 0.0000545 0.51679 43.6364
307 3BZ3 YAM 0.00002122 0.43698 43.8406
308 4TWP AXI 0.0000158 0.46984 43.9114
309 5FBN 5WF 0.000007509 0.44102 43.9114
310 2ZV2 609 0.0000003296 0.67887 44.2953
311 5UOX 8GY 0.00000005316 0.65903 44.6494
312 4D2S DYK 0.0000025 0.62418 44.7183
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