Receptor
PDB id Resolution Class Description Source Keywords
3A9Z 1.55 Å EC: 4.4.1.16 CRYSTAL STRUCTURE OF RAS SELENOCYSTEINE LYASE IN COMPLEX WIT SELENOPROPIONATE RATTUS NORVEGICUS SELENOCYSTEINE PLP LYASE PYRIDOXAL PHOSPHATE TRANSFERASE
Ref.: REACTION MECHANISM AND MOLECULAR BASIS FOR SELENIUM DISCRIMINATION OF SELENOCYSTEINE LYASE. J.BIOL.CHEM. V. 285 12133 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
PLP A:501;
B:501;
Part of Protein;
Part of Protein;
none;
none;
submit data
247.142 C8 H10 N O6 P Cc1c(...
PO4 A:504;
A:505;
Invalid;
Invalid;
none;
none;
submit data
94.971 O4 P [O-]P...
SLP A:502;
B:503;
Valid;
Valid;
none;
none;
submit data
153.039 C3 H6 O2 Se C(C[S...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3A9Y 1.85 Å EC: 4.4.1.16 CRYSTAL STRUCTURE OF RAT SELENOCYSTEINE LYASE IN COMPLEX WIT CYSTEINE RATTUS NORVEGICUS SELENOCYSTEINE PLP LYASE PYRIDOXAL PHOSPHATE TRANSFERASE
Ref.: REACTION MECHANISM AND MOLECULAR BASIS FOR SELENIUM DISCRIMINATION OF SELENOCYSTEINE LYASE. J.BIOL.CHEM. V. 285 12133 2010
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3A9Y Ki = 9.6 mM CYS C3 H7 N O2 S C([C@@H](C....
2 3A9Z - SLP C3 H6 O2 Se C(C[SeH])C....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3A9Y Ki = 9.6 mM CYS C3 H7 N O2 S C([C@@H](C....
2 3A9Z - SLP C3 H6 O2 Se C(C[SeH])C....
50% Homology Family (4)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3A9Y Ki = 9.6 mM CYS C3 H7 N O2 S C([C@@H](C....
2 3A9Z - SLP C3 H6 O2 Se C(C[SeH])C....
3 4R5F - PMP C8 H13 N2 O5 P Cc1c(c(c(c....
4 4HVK - PMP C8 H13 N2 O5 P Cc1c(c(c(c....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: SLP; Similar ligands found: 4
No: Ligand ECFP6 Tc MDL keys Tc
1 SLP 1 1
2 SIN 0.5625 0.6
3 3OH 0.5 0.75
4 BAL 0.473684 0.625
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3A9Y; Ligand: CYS; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 1) in the query (biounit: 3a9y.bio1) has 14 residues
No: Leader PDB Ligand Sequence Similarity
APoc FAQ
Feedback