Receptor
PDB id Resolution Class Description Source Keywords
3AB3 2.4 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF P115RHOGEF RGS DOMAIN IN COMPLEX WITH G MUS MUSCULUS SIGNAL TRANSDUCTION PROTEIN COMPLEX GTP-BINDING MEMBRANETRANSDUCER LIPOPROTEIN NUCLEOTIDE-BINDING PALMITATE PHOSPHOPROTEIN GTPASE ACTIVATION GUANINE-NUCLEOTIDE RELEAFACTOR SIGNALING PROTEIN-MEMBRANE PROTEIN COMPLEX
Ref.: IDENTIFICATION OF CRITICAL RESIDUES IN G(ALPHA)13 F STIMULATION OF P115RHOGEF ACTIVITY AND THE STRUCTUR G(ALPHA)13-P115RHOGEF REGULATOR OF G PROTEIN SIGNAL HOMOLOGY (RH) DOMAIN COMPLEX. J.BIOL.CHEM. V. 286 20625 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
ALF A:601;
C:602;
Invalid;
Invalid;
none;
none;
submit data
102.975 Al F4 F[Al-...
GDP A:401;
C:402;
Valid;
Valid;
none;
none;
submit data
443.201 C10 H15 N5 O11 P2 c1nc2...
MG A:501;
C:502;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3AB3 2.4 Å NON-ENZYME: BINDING CRYSTAL STRUCTURE OF P115RHOGEF RGS DOMAIN IN COMPLEX WITH G MUS MUSCULUS SIGNAL TRANSDUCTION PROTEIN COMPLEX GTP-BINDING MEMBRANETRANSDUCER LIPOPROTEIN NUCLEOTIDE-BINDING PALMITATE PHOSPHOPROTEIN GTPASE ACTIVATION GUANINE-NUCLEOTIDE RELEAFACTOR SIGNALING PROTEIN-MEMBRANE PROTEIN COMPLEX
Ref.: IDENTIFICATION OF CRITICAL RESIDUES IN G(ALPHA)13 F STIMULATION OF P115RHOGEF ACTIVITY AND THE STRUCTUR G(ALPHA)13-P115RHOGEF REGULATOR OF G PROTEIN SIGNAL HOMOLOGY (RH) DOMAIN COMPLEX. J.BIOL.CHEM. V. 286 20625 2011
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 473 families.
1 3AB3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 355 families.
1 3AB3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 272 families.
1 3AB3 - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GDP; Similar ligands found: 153
No: Ligand ECFP6 Tc MDL keys Tc
1 GDP 1 1
2 GTP 0.909091 1
3 GP3 0.881579 0.973684
4 GNH 0.858974 0.986667
5 GNP 0.839506 0.973684
6 G 0.828947 0.986486
7 5GP 0.828947 0.986486
8 G1R 0.82716 0.986667
9 GCP 0.82716 0.973684
10 GSP 0.817073 0.948718
11 GAV 0.797619 0.961039
12 GMV 0.792683 0.973684
13 G2P 0.77381 0.961039
14 G2R 0.770115 0.961039
15 GDP MG 0.759036 0.923077
16 GP2 0.756098 0.961039
17 GDP BEF 0.75 0.9
18 GDD 0.747253 0.961039
19 GKE 0.747253 0.961039
20 GDC 0.747253 0.961039
21 GPG 0.741573 0.961039
22 G3D 0.732558 0.986486
23 ALF 5GP 0.729412 0.888889
24 Y9Z 0.728261 0.902439
25 GTP MG 0.724138 0.923077
26 BEF GDP 0.724138 0.888889
27 G5P 0.723404 0.973684
28 GFB 0.72043 0.961039
29 GTG 0.72043 0.936709
30 GDR 0.72043 0.961039
31 G4P 0.715909 0.986486
32 GCP G 0.715909 0.935065
33 6CK 0.712766 0.936709
34 G3A 0.712766 0.973684
35 GDP ALF 0.7 0.888889
36 GDP AF3 0.7 0.888889
37 YGP 0.698925 0.901235
38 JB2 0.697917 0.961039
39 GKD 0.697917 0.961039
40 GDX 0.690722 0.973684
41 GPD 0.690722 0.925
42 GMP 0.684211 0.88
43 0O2 0.666667 0.986486
44 G G 0.659574 0.935065
45 JB3 0.656863 0.948718
46 NGD 0.650485 0.961039
47 GDP 7MG 0.636364 0.911392
48 DGI 0.636364 0.923077
49 U2G 0.634615 0.936709
50 GPX 0.634409 0.946667
51 IDP 0.632184 0.972973
52 2MD 0.632075 0.891566
53 CAG 0.62963 0.880952
54 CG2 0.622642 0.936709
55 FEG 0.619048 0.879518
56 MGD 0.614679 0.891566
57 ZGP 0.613208 0.869048
58 GH3 0.612903 0.973333
59 3GP 0.611765 0.946667
60 MD1 0.607143 0.891566
61 PGD 0.59292 0.925
62 DGT 0.591398 0.923077
63 BGO 0.588785 0.924051
64 TPG 0.582609 0.840909
65 DBG 0.582609 0.948718
66 2GP 0.574713 0.96
67 FE9 0.570175 0.776596
68 I2C FE2 CMO CMO 0.566372 0.808989
69 G A A A 0.553571 0.923077
70 MGP 0.553191 0.961039
71 U A G G 0.548673 0.935065
72 G4M 0.548387 0.880952
73 6G0 0.547368 0.961039
74 G1R G1R 0.542373 0.924051
75 P2G 0.527473 0.883117
76 PGD O 0.525 0.850575
77 ADP 0.522222 0.92
78 GGM 0.517544 0.901235
79 DG 0.516484 0.910256
80 DGP 0.516484 0.910256
81 P1G 0.516129 0.871795
82 G G U 0.509259 0.935065
83 G1G 0.508475 0.925
84 IMP 0.505495 0.959459
85 G C 0.504348 0.9
86 GPC 0.491525 0.879518
87 G7M 0.483871 0.948052
88 6AD 0.479592 0.841463
89 ATP 0.473684 0.92
90 G2Q 0.471154 0.961039
91 U G A 0.469697 0.888889
92 5FA 0.46875 0.92
93 AQP 0.46875 0.92
94 GTA 0.468468 0.936709
95 7DD 0.468085 0.906667
96 G G G RPC 0.466102 0.875
97 SGP 0.463158 0.82716
98 01G 0.462963 0.902439
99 B4P 0.457447 0.894737
100 AP5 0.457447 0.894737
101 A2D 0.456522 0.894737
102 G G G C 0.455285 0.9125
103 ACQ 0.454545 0.896104
104 5GP 5GP 0.454545 0.883117
105 ANP 0.454545 0.896104
106 A G C C 0.451613 0.911392
107 APC G U 0.45082 0.886076
108 G U34 0.449153 0.888889
109 DG DG 0.448598 0.865854
110 ITT 0.447917 0.868421
111 BA3 0.446809 0.894737
112 35G 0.444444 0.933333
113 C2E 0.444444 0.921053
114 PCG 0.444444 0.933333
115 MGO 0.441176 0.864198
116 AN2 0.4375 0.907895
117 G C C C 0.4375 0.924051
118 M33 0.43299 0.883117
119 UCG 0.429688 0.911392
120 A G U 0.42963 0.888889
121 ACP 0.428571 0.896104
122 MGQ 0.424528 0.935897
123 7DT 0.424242 0.906667
124 APR 0.424242 0.894737
125 AR6 0.424242 0.894737
126 93A 0.42268 0.833333
127 A4P 0.420168 0.869048
128 SAP 0.42 0.873418
129 AD9 0.42 0.896104
130 AGS 0.42 0.873418
131 G8D 0.42 0.875
132 CA0 0.418367 0.896104
133 ATF 0.417476 0.884615
134 AGO 0.414634 0.888889
135 NIA 0.413043 0.82716
136 MGV 0.412844 0.890244
137 TAT 0.411765 0.884615
138 A1R 0.411215 0.839506
139 ADQ 0.411215 0.871795
140 RGT 0.410714 0.909091
141 CGP 0.409836 0.86747
142 AMP 0.408602 0.893333
143 A 0.408602 0.893333
144 UP5 0.40678 0.873418
145 C2R 0.406593 0.906667
146 AMZ 0.406593 0.918919
147 JBT 0.405882 0.778947
148 A22 0.40566 0.907895
149 25L 0.405405 0.907895
150 ADX 0.40404 0.809524
151 8OD 0.401961 0.946667
152 4TC 0.4 0.851852
153 50T 0.4 0.883117
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3AB3; Ligand: GDP; Similar sites found: 486
This union binding pocket(no: 1) in the query (biounit: 3ab3.bio1) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1VHT BA3 0.0002731 0.47801 2.29358
2 5D9G GLU ASN LEU TYR PHE GLN 0.01838 0.40483 2.43902
3 3BJE URA 0.02381 0.40261 2.43902
4 3DC4 ADP 0.0000793 0.53003 2.61628
5 5AHO TLA 0.0307 0.40136 2.67857
6 2BEK ATP 0.0000925 0.46935 2.72374
7 4YMU ATP 0.00007969 0.52245 2.72727
8 3FWY ADP 0.00003148 0.5091 2.84553
9 2C04 GCP 0.00004555 0.50202 2.84553
10 2O0J ADP 0.008381 0.42666 2.84553
11 3DKP ADP 0.0007614 0.46797 2.85714
12 3FVQ ATP 0.001031 0.43396 3.06407
13 4WOP CTP 0.003712 0.42155 3.11111
14 3VX3 ADP 0.0003763 0.4569 3.22581
15 1KK1 GNP 0.0000000001104 0.81356 3.25203
16 1JWY GDP 0.00000006139 0.63732 3.25203
17 2VVG ADP 0.000005982 0.60302 3.25203
18 5I34 GDP 0.000008024 0.55602 3.25203
19 2IYL GDP 0.0000161 0.5491 3.25203
20 4AG5 ADP 0.00015 0.52054 3.25203
21 4XGU ADP 0.00009359 0.48822 3.25203
22 1JWY ADP 0.000274 0.48354 3.25203
23 4B47 GDP 0.00000000007601 0.8216 3.31492
24 2JLR ANP 0.001805 0.4357 3.31492
25 3BRE C2E 0.02794 0.40421 3.35196
26 2CBZ ATP 0.00000252 0.63384 3.37553
27 1GWN GTP 0.0000004302 0.57686 3.41463
28 3ZFD ANP 0.0001399 0.49142 3.4188
29 2W58 ADP 0.000005994 0.6094 3.46535
30 1OYY AGS 0.00571 0.42553 3.59116
31 4IOK XPO 0.00231 0.40085 3.59116
32 3TK1 GDP 0.000000003625 0.75147 3.63636
33 3MD0 GDP 0.000000000972 0.76661 3.65854
34 1JJ7 ADP 0.00000358 0.62057 3.65854
35 2XT3 ADP 0.0000101 0.58728 3.65854
36 4NCN GTP 0.0000001191 0.57569 3.65854
37 4TMZ GSP 0.0000001182 0.57535 3.65854
38 1WF3 GNP 0.00000007864 0.54835 3.65854
39 5TSH ANP 0.0000497 0.52539 3.65854
40 5TSH ADP 0.0002026 0.51342 3.65854
41 4LYA ATP 0.0001326 0.49843 3.65854
42 2FAH GDP 0.0003913 0.46566 3.65854
43 2VWT PYR 0.02245 0.40398 3.65854
44 1IYE PGU 0.04545 0.40179 3.65854
45 1T5C ADP 0.000003183 0.61946 3.72493
46 2WIC GNP 0.0000000004283 0.75799 3.74532
47 1M7B GTP 0.0000006156 0.57028 3.80435
48 5J1J ANP 0.00006431 0.46681 3.85965
49 1WDT GTP 0.0000003556 0.58751 3.8674
50 1R6B ADP 0.0003319 0.4796 3.8674
51 4UAP NGA 0.00802 0.42105 3.94737
52 1RRC ADP 0.00001186 0.58709 3.98671
53 1OFH ADP 0.0002614 0.47889 4.02299
54 3EWA ANP 0.0001694 0.49959 4.03727
55 5I0H ADP BEF 0.001473 0.4274 4.06504
56 2FSH ANP 0.007708 0.4237 4.06504
57 4ZG4 VO4 ADP 0.001848 0.40918 4.14365
58 4GOX A3P 0.001043 0.42056 4.15335
59 3LRE ADP 0.000005495 0.60345 4.22535
60 4NON GDP 0.0000002297 0.52185 4.23077
61 2PL3 ADP 0.0005937 0.4791 4.23729
62 1G6H ADP 0.000005866 0.60568 4.28016
63 4HSE ADP 0.0002607 0.48456 4.28212
64 1AQU A3P 0.003936 0.41653 4.3771
65 4R98 GNH 0.000000005496 0.71704 4.42804
66 4RD0 GDP 0.00000002202 0.61709 4.47154
67 4V03 ADP 0.00002184 0.52865 4.47154
68 2D2F ADP 0.0002447 0.52478 4.47154
69 2DPY ADP 0.0009205 0.47569 4.47154
70 4PX9 ADP 0.000743 0.47426 4.47154
71 5VGR GDP 0.0002417 0.47003 4.47154
72 4QOS ADP 0.0004713 0.46707 4.47154
73 1ION ADP 0.00001084 0.54269 4.52675
74 3BOS CDP 0.00004952 0.52547 4.54545
75 4D81 ADP 0.0001118 0.49022 4.59364
76 3Q9L ATP 0.0001928 0.47436 4.61538
77 3EZ2 ADP 0.00006324 0.52744 4.69613
78 4IHQ ADP 0.0001158 0.51438 4.69613
79 3KV5 OGA 0.02545 0.40143 4.71311
80 5KSP GDP 0.000001759 0.58718 4.73684
81 1NJF ADP 0.0004165 0.455 4.8
82 1NJF AGS 0.0004381 0.44199 4.8
83 4FCW ADP 0.0002763 0.48337 4.82315
84 2HF9 GSP 0.00000005867 0.62954 4.86726
85 1DAR GDP 0.0000000002761 0.77997 4.87805
86 1IHU AF3 0.00008564 0.47092 4.87805
87 1IHU ADP 0.00009006 0.46194 4.87805
88 5XDR ADP 0.002044 0.44227 4.87805
89 3TBK ANP 0.005335 0.4367 4.87805
90 2X7I CIT 0.01271 0.40863 4.87805
91 5E5U MLI 0.004485 0.40787 4.87805
92 4XFR CIT 0.02207 0.40561 4.87805
93 1B0U ATP 0.001672 0.4372 4.96183
94 5KSZ GCP 0.00001738 0.53323 4.97238
95 1XKV ATP 0.0001557 0.48927 4.97238
96 2D7D ADP 0.002108 0.44653 4.97238
97 1GXS BEZ 0.02556 0.40355 5.18518
98 1U0J ADP 0.0007928 0.47286 5.24345
99 5GJC ATP 0.0002938 0.488 5.24862
100 2B8W ALF 5GP 0.0005723 0.42291 5.24862
101 3CNL GNP 0.0000000005355 0.77948 5.28455
102 1FP6 ADP 0.00008949 0.49458 5.28455
103 1G6O ADP 0.0001769 0.48672 5.28455
104 5HR5 ADP 0.000696 0.44976 5.28455
105 4KBF AMP 0.003208 0.44267 5.28455
106 2BCG GDP 0.0000001728 0.60105 5.33981
107 4E03 ADP 0.000003229 0.57471 5.33981
108 3B5J 12D 0.00005637 0.53759 5.34979
109 2IS6 ADP 0.0001665 0.49996 5.52486
110 5M7P ADP 0.0005264 0.45061 5.52486
111 1LVG ADP 0.000003306 0.60044 5.55556
112 1UJ2 C5P 0.0002755 0.41962 5.55556
113 1UJ2 ADP 0.0009279 0.40078 5.55556
114 2OG2 MLI 0.0001051 0.54784 5.57103
115 2Y8E GNP 0.00000001223 0.59188 5.58659
116 1OXV ANP 0.0001151 0.51451 5.66572
117 5FG3 GDP 0.0000000002912 0.79262 5.69106
118 3COB ADP 0.00001012 0.58577 5.69106
119 2VF7 ADP 0.0005955 0.4676 5.69106
120 2FNA ADP 0.0001361 0.46264 5.69106
121 2WOJ ADP ALF 0.00004545 0.45026 5.69106
122 1NY5 ADP 0.001875 0.43076 5.69106
123 2ZJ5 ADP 0.02502 0.40432 5.69106
124 1OIX GDP 0.00000001251 0.59318 5.75916
125 1OIV GDP 0.000000116 0.55611 5.75916
126 1BG2 ADP 0.0000008992 0.65015 5.84615
127 1RYH GNP 0.000000223 0.62057 5.91133
128 5K5Z ANP 0.00004953 0.4641 6.05096
129 3T1O GDP 0.0000000001684 0.76469 6.06061
130 4R43 GDP 0.0003261 0.48581 6.07735
131 3FKQ ATP 0.0001346 0.48125 6.07735
132 1W5T ADP 0.001783 0.43172 6.07735
133 1W5T ANP 0.001401 0.42833 6.07735
134 5M04 GDP 0.0000000001345 0.8093 6.09756
135 1G7S GDP 0.000000000448 0.75706 6.09756
136 3EC1 GDP 0.00000001725 0.68212 6.09756
137 2Y65 ADP 0.000003524 0.61186 6.09756
138 3SFV GDP 0.0000000674 0.6109 6.09756
139 2WHX ADP 0.0001212 0.52645 6.09756
140 5LB3 ADP 0.0008392 0.47163 6.09756
141 1FNN ADP 0.0004842 0.45217 6.09756
142 5X40 ACP 0.003825 0.41348 6.09756
143 2IXE ATP 0.002288 0.41171 6.09756
144 4CFT H4B 0.01892 0.40474 6.09756
145 2PZE ATP 0.000009585 0.59312 6.11354
146 4KFU ACP 0.0000161 0.57145 6.13208
147 3BC1 GNP 0.00000003433 0.57627 6.15385
148 5MVR ADP 0.00004998 0.52527 6.17284
149 1X1R GDP 0.0000001142 0.54739 6.17978
150 3A1S GDP 0.000006491 0.56038 6.20155
151 4ZNL BEF ADP 0.00005323 0.51718 6.20438
152 1E96 GTP 0.0000006682 0.53092 6.25
153 3KJI ADP 0.0002232 0.47667 6.29921
154 4JLV ADP 0.0003208 0.49239 6.3197
155 5GOE GDP 0.000000004693 0.69798 6.35359
156 5FTB ANP 0.0001197 0.49455 6.35359
157 5FHD ADP ALF 0.0005114 0.44684 6.35359
158 2ZTS ADP 0.001011 0.43837 6.35359
159 2WJG GDP 0.0000000001994 0.78681 6.38298
160 2HV8 GTP 0.00000006994 0.56561 6.39535
161 2XTN GTP 0.0001522 0.45571 6.41026
162 3SBD GNP 0.000000568 0.53362 6.41711
163 1MH1 GNP 0.000000115 0.5463 6.45161
164 1G16 GDP 0.000001746 0.54018 6.47059
165 1YZN GNP 0.00000008882 0.55227 6.48649
166 2OBM ADP 0.001036 0.48104 6.50407
167 1G4U GDP 0.000001233 0.56419 6.52174
168 3T12 GDP ALF 0.000000002138 0.65741 6.61765
169 3B9Q MLI 0.00002049 0.57008 6.62252
170 3Q72 GNP 0.0000000008256 0.77013 6.62651
171 3P4X ADP 0.000103 0.51691 6.62983
172 2CHG ANP 0.0002305 0.47094 6.63717
173 2FJU GSP 0.000001221 0.55771 6.74157
174 1DS6 GDP 0.0000001057 0.65483 6.77083
175 1JJV ATP 0.000008998 0.58429 6.79612
176 1HE1 GDP 0.000002258 0.54642 6.81818
177 3U6B GDP 0.00000000008828 0.81838 6.85279
178 5JBQ GDP 0.0000000002265 0.78414 6.85279
179 4G5G GDP 0.0000000003106 0.77749 6.85279
180 3U6K GDP 0.0000000009344 0.75432 6.85279
181 1KO8 6PG 0.0003432 0.45863 6.85714
182 3W5J GDP 0.00000004557 0.70937 6.86275
183 1D8T GDP 0.0000000004067 0.77182 6.87023
184 2BVN GNP 0.000000002632 0.69903 6.87023
185 5MZN ADP 0.002257 0.4558 6.90608
186 2QEN ADP 0.00006091 0.49645 6.91057
187 4XTR ADP 0.00001664 0.51539 6.91244
188 4XTR ATP 0.00003216 0.47915 6.91244
189 4XVU ATP 0.00003665 0.47702 6.91244
190 4U00 ADP 0.000007997 0.59925 6.96721
191 2FH5 GTP 0.00000002179 0.63164 7.02703
192 2F9L GDP 0.0000001063 0.57814 7.03518
193 1Z08 GNP 0.00000002241 0.6054 7.05882
194 2ZEJ GDP 0.0000007713 0.51379 7.06522
195 5J1S ATP 0.002435 0.40001 7.11297
196 1Z2A GDP 0.0000000165 0.60975 7.14286
197 2D7C GTP 0.00000001321 0.59066 7.18563
198 2WJH GDP 0.0000000007566 0.7463 7.22892
199 2WJH FLC 0.0000008721 0.59322 7.22892
200 4J0Q GDP 0.0000000000608 0.82642 7.31707
201 3IO3 ADP 0.00002109 0.51095 7.31707
202 2ZPA ADP 0.001119 0.43647 7.31707
203 4IDN GNP 0.0006248 0.43566 7.31707
204 1XX6 ADP 0.0003159 0.48648 7.32984
205 4BQS ADP 0.00003965 0.53014 7.38636
206 3NKV GNP 0.00000007417 0.56456 7.42857
207 4LPS GDP 0.0000001552 0.63701 7.43802
208 3IUY AMP 0.01122 0.41125 7.45614
209 5IFS ADP 0.0001562 0.48921 7.45856
210 1JI0 ATP 0.00005268 0.53909 7.5
211 5N69 ADP 0.0003489 0.46791 7.53769
212 1G3Q ADP 0.00000725 0.5581 7.59494
213 3GJ0 GDP 0.000000003713 0.72529 7.69231
214 3GJ4 GDP 0.000000005134 0.71847 7.69231
215 3GJ8 GDP 0.000000003586 0.71436 7.69231
216 3GJ5 GDP 0.00000000413 0.71146 7.69231
217 5L3V GDP 0.000007609 0.5498 7.69231
218 2C77 GNP 0.000000006664 0.65339 7.72358
219 2C78 GNP 0.0000000095 0.63137 7.72358
220 1Y63 ADP 0.000007194 0.56605 7.72358
221 1F9V ADP 0.00003622 0.55326 7.72358
222 1SQ5 ADP 0.0001142 0.50151 7.72358
223 5L3R GCP 0.00002838 0.47348 7.72358
224 1Z6T ADP 0.0005831 0.45315 7.72358
225 1IN4 ADP 0.0004952 0.45175 7.72358
226 3ZQ6 ADP ALF 0.00003903 0.45113 7.72358
227 2GK6 ADP 0.003281 0.4475 7.72358
228 4A4Z ANP 0.003289 0.43716 7.72358
229 4QYS PLR 0.007614 0.41521 7.72358
230 1V8K ANP 0.00004797 0.52614 7.73481
231 3WYF GTP 0.00000002175 0.56297 7.76256
232 4CVN ADP 0.00006244 0.53532 7.8534
233 1IBR GNP 0.00000001518 0.57911 7.87037
234 5BXQ GDP 0.000000003523 0.71473 7.87402
235 3E70 GDP 0.000009386 0.5528 7.92683
236 2HCJ GDP 0.0000000001849 0.80242 8.0597
237 2NCD ADP 0.00002509 0.56158 8.13008
238 4H1V GNP 0.000002655 0.55649 8.13008
239 4RZ3 ADP 0.0004868 0.45661 8.13008
240 4PC3 GDP 0.00000003178 0.65022 8.15603
241 2ZFI ADP 0.0001798 0.49834 8.19672
242 1HTW ADP 0.0000759 0.5099 8.22785
243 4IEE AGS 0.0006758 0.47631 8.28729
244 3T34 GDP 0.000003292 0.51855 8.33333
245 1BO4 COA 0.007626 0.41942 8.33333
246 2KIN ADP 0.000001791 0.63461 8.40336
247 3BER AMP 0.0139 0.40672 8.43373
248 1S8F GDP 0.0000001085 0.53818 8.47458
249 2OZE AGS 0.000611 0.44781 8.53659
250 2GWH A3P 0.005216 0.41112 8.53659
251 4LJ9 ACP 0.0007688 0.46776 8.55457
252 5JCP GDP ALF 0.00000093 0.57659 8.56354
253 4P3Y GDP 0.00000000009074 0.81778 8.79121
254 1GXU 2HP 0.0009669 0.47921 8.79121
255 5URY PAM 0.008372 0.43055 8.90411
256 4LC1 GDP 0.00000005189 0.66981 8.94309
257 4LX0 BEF GDP 0.00000005756 0.55831 8.94309
258 3CPJ GDP 0.00000006571 0.63598 8.96861
259 1KAO GDP 0.000000002226 0.69224 8.98204
260 5KUT GDP 0.0000008654 0.60174 8.99471
261 4R2I ANP 0.001548 0.46417 9.11602
262 3DEF GDP 0.00004582 0.50769 9.16031
263 2ZR9 DTP 0.00009426 0.51193 9.16905
264 1H65 GDP 0.0001525 0.46162 9.25926
265 3WYG GTP 0.00000001334 0.56987 9.34066
266 3KTA AP5 0.0005314 0.45967 9.34066
267 1W0J ADP 0.0000562 0.46463 9.34959
268 2CK3 ANP 0.001489 0.4311 9.34959
269 1W0J ADP BEF 0.00144 0.42191 9.34959
270 2CK3 ADP 0.002006 0.40778 9.34959
271 1TU3 GNP 0.000000135 0.55351 9.35672
272 4WEI GLC GAL 0.003587 0.45488 9.38628
273 1R2Q GNP 0.00000006264 0.50046 9.41177
274 2NGR GDP 0.00000008241 0.65001 9.42408
275 1A4R GNH 0.000002172 0.56034 9.42408
276 1A4R GDP 0.00000403 0.54198 9.42408
277 2NGR AF3 0.00125 0.46891 9.42408
278 1YVD GNP 0.0000001382 0.55387 9.46746
279 2WMO GTP 0.0000007704 0.59571 9.47368
280 3MJH GTP 0.0000000603 0.56659 9.52381
281 1GOJ ADP 0.000004161 0.61018 9.57747
282 2WKQ GTP 0.0000004587 0.55484 9.63855
283 1WA5 GTP 0.00000001931 0.53953 9.65909
284 3DZD ADP 0.000288 0.47168 9.66851
285 2W2X GSP 0.0000008955 0.5634 9.67742
286 4GDX GLU 0.01989 0.41056 9.74359
287 1D2E GDP 0.000000003538 0.69323 9.7561
288 1YTM ATP 0.0002738 0.45831 9.7561
289 3RC3 ANP 0.001664 0.45685 9.7561
290 3REF GDP 0.000001344 0.54519 9.79381
291 1D5C GDP 0.00000004458 0.6348 9.87654
292 4YC7 GNP 0.0000006621 0.55795 9.94475
293 3M1I GTP 0.00000002039 0.57415 9.94764
294 3IIJ ADP 0.00003832 0.53086 10
295 4ITR GDP 0.000001584 0.5595 10.1266
296 1CR1 TTP 0.001231 0.43069 10.1351
297 1I4D GDP 0.0000001322 0.6606 10.2679
298 1GRN GDP 0.000000433 0.59124 10.3448
299 3QBT GNP 0.00000008078 0.56145 10.3448
300 4LHW GNP 0.000000122 0.55673 10.3448
301 3TNF GNP 0.00000004053 0.55437 10.3448
302 1GRN AF3 0.01666 0.41134 10.3448
303 2G77 GDP 0.00000001014 0.66318 10.4972
304 2G77 AF3 0.004224 0.4464 10.4972
305 5WDR GNP 0.00000002443 0.57199 10.5263
306 4YDS ATP 0.00008946 0.52735 10.5263
307 1G41 ADP 0.000399 0.47041 10.5691
308 5GVR LMR 0.000447 0.50277 10.6838
309 4TTQ ATP 0.00003406 0.53334 10.6977
310 5HCN GCP 0.0000004896 0.61343 10.728
311 2AWN ADP 0.000004485 0.61813 10.7735
312 4ZKD GDP 0.00000001089 0.57869 10.7735
313 5IRN ADP 0.00007808 0.49725 10.7735
314 3RLF ANP 0.001739 0.41002 10.7735
315 1YQT ADP 0.00007714 0.53688 10.9756
316 4DID GDP 0.0000003734 0.619 11.1842
317 1SVI GDP 0.0000001334 0.66039 11.2821
318 1XTQ GDP 0.00000009373 0.58017 11.2994
319 2C9O ADP 0.000325 0.45516 11.326
320 2XAU ADP 0.001898 0.43912 11.326
321 5IRR GSP 0.00001909 0.49795 11.3636
322 3CH5 GDP 0.000000003082 0.71747 11.5385
323 2EFE GNH 0.0000002527 0.6096 11.6022
324 1Z06 GNP 0.00000008516 0.57055 11.6402
325 1G7C 5GP 0.00000002293 0.68699 11.7021
326 3B7G ANP 0.001272 0.45202 11.7391
327 5CK5 GDP 0.00000003359 0.69016 11.7886
328 3A4M ADP 0.00001523 0.56658 11.7886
329 4C4P GNP 0.00000004062 0.56438 11.7886
330 3E5H GNP 0.00000003465 0.57739 11.7978
331 1W7J ADP BEF 0.0009116 0.44459 11.9205
332 3WYA GDP 0.00000000005268 0.81481 11.9816
333 4HI0 GDP 0.0000002201 0.58917 12.1951
334 3BFX A3P 0.001741 0.42817 12.1951
335 3GJ7 GDP 0.000000003007 0.72973 12.2449
336 1M7G AV2 0.000005126 0.58166 12.3223
337 5L3W GDP 0.00008884 0.50053 12.4183
338 2EW1 GNP 0.0000004971 0.55262 12.4378
339 2GDJ ANP 0.0002028 0.49581 12.5
340 5JCZ GDP 0.00000004526 0.62617 12.6016
341 2Z5F A3P 0.003375 0.41216 12.6016
342 1L2T ATP 0.00155 0.40522 12.766
343 5L3S GNP 0.00004161 0.46761 12.8378
344 2QN6 GDP 0.0000000001027 0.81511 12.9032
345 3UIE ANP 0.0001816 0.4862 13
346 2CE7 ADP 0.0001167 0.49506 13.0081
347 1K6M AGS 0.001656 0.4115 13.0081
348 4PPF FLC 0.000002979 0.62112 13.1429
349 5UWQ GNP 0.00000001399 0.5798 13.2867
350 5DIF GNP 0.0000000141 0.57977 13.2867
351 5UWU GNP 0.00000001537 0.57833 13.2867
352 5UWW GNP 0.00000001556 0.57825 13.2867
353 5UWI GNP 0.00000001582 0.57796 13.2867
354 5UWR GNP 0.00000001611 0.57759 13.2867
355 5DHF GNP 0.00000001689 0.57697 13.2867
356 5UWT GNP 0.0000000172 0.57668 13.2867
357 5UWH GNP 0.00000001717 0.57653 13.2867
358 5UWO GNP 0.00000001809 0.57608 13.2867
359 5UWJ GNP 0.00000001826 0.57592 13.2867
360 5UWP GNP 0.00000001504 0.56849 13.2867
361 5UWS GNP 0.00000002012 0.56436 13.2867
362 5DI9 GNP 0.00000002071 0.56407 13.2867
363 1NRJ GTP 0.00000008723 0.60616 13.2911
364 1PUJ GNP 0.000000001668 0.70797 13.4752
365 4HAT GNP 0.0000000123 0.57164 13.5714
366 4DSU GDP 0.00000003726 0.56539 13.7566
367 5UQW GDP 0.0000001533 0.56169 13.7566
368 3GJX GTP 0.00000002941 0.64068 13.8211
369 3TKL GTP 0.0000001982 0.55897 13.8211
370 5H67 ATP 0.00619 0.41948 14.0704
371 4OI4 ATP 0.0004768 0.43198 14.0884
372 2VB6 ADP BEF 0.002218 0.40638 14.094
373 1SKQ GDP 0.00000000002808 0.84309 14.3646
374 5TB5 GDP 0.00000001594 0.67346 14.5946
375 5TAR GDP 0.00000002697 0.65343 14.5946
376 4QM7 GTP 0.0002188 0.49421 14.6199
377 2QZ4 ADP 0.00005971 0.50849 14.6341
378 1D2N ANP 0.0008799 0.43687 14.7059
379 4WZ6 ATP 0.00002522 0.56312 14.8276
380 1VG0 GDP 0.00000005344 0.64003 14.9758
381 1VG8 GNP 0.000000006002 0.59172 14.9758
382 2C5L GTP 0.00000002564 0.57094 15.0289
383 4YS0 ADP 0.007599 0.40388 15.0407
384 4NOS H2B 0.02252 0.40343 15.0407
385 1XPJ TLA 0.02943 0.41071 15.0794
386 5XCO GDP 0.00000009228 0.62933 15.2047
387 4K81 GTP 0.00000009016 0.54424 15.2047
388 5O2T GSP 0.00000007133 0.55614 15.3846
389 3BFV ADP 0.00001951 0.54506 15.4472
390 3VMF GTP 0.00000002137 0.58003 15.4696
391 3WXM GTP 0.00000005553 0.56574 15.4696
392 2UZI GTP 0.00000002171 0.58214 15.6627
393 1CLU DBG 0.0000007661 0.43193 15.6627
394 3ZS9 ADP ALF 0.00003813 0.45262 15.7895
395 3RAB GNP 0.00000001607 0.58845 15.9763
396 2A9K GDP 0.00000001001 0.66343 16.0428
397 1OW3 GDP 0.0000003119 0.59753 16.0622
398 5E95 GDP 0.0000001063 0.61815 16.0714
399 1LFD GNP 0.00000002583 0.58081 16.1677
400 1T9D P22 0.02328 0.40386 16.2602
401 1WQ1 GDP 0.00000005956 0.58862 16.2651
402 3DDC GNP 0.00000002199 0.57469 16.2651
403 1NVV GNP 0.00000002299 0.57376 16.2651
404 1NVU GTP 0.0000000245 0.57146 16.2651
405 1WQ1 AF3 0.01159 0.42701 16.2651
406 1NF3 GNP 0.0000004265 0.53657 16.4103
407 1YZQ GNP 0.00000001735 0.57594 16.4706
408 5IRC GDP 0.000001249 0.58602 16.6667
409 4KVG GTP 0.00000004394 0.57362 16.6667
410 4GBM A3P 0.001947 0.41014 16.6667
411 1VG1 GDP 0.000000006093 0.70348 16.7568
412 4D0N GDP 0.00000008043 0.66059 16.7568
413 5HPY GDP 0.0000002462 0.60205 16.7568
414 3LXR GDP 0.0000007674 0.59579 16.7568
415 1VG9 GDP 0.00000001937 0.58198 16.7568
416 1CXZ GSP 0.0000007101 0.55683 17.033
417 2RCN GDP 0.000000004646 0.72058 17.0732
418 1NST A3P 0.007763 0.40347 17.0732
419 4DKX GDP 0.000000001383 0.74606 17.1296
420 1UAD GNP 0.00000002971 0.57875 17.1429
421 4XSH GSP 0.000002935 0.54793 17.3184
422 4HDO GNP 0.0000000336 0.56754 17.3653
423 4HDQ GNP 0.00000003372 0.56731 17.3653
424 3X1Z GNP 0.00000003276 0.55784 17.3653
425 1O3Y GTP 0.000000006776 0.6224 17.4699
426 1TX4 ALF GDP 0.0000009776 0.54118 17.5141
427 1UPT GTP 0.00000006895 0.59649 17.5439
428 2FFQ GSP 0.00000000682 0.5902 17.5439
429 1U8Z GDP 0.00000008276 0.58212 17.8571
430 1R0X ATP 0.00005295 0.53127 17.8862
431 1KMQ GNP 0.0000004623 0.55402 17.9348
432 5UFQ GNP 0.0000001103 0.5567 18.0328
433 3GJ3 GDP 0.000000001973 0.7386 18.1818
434 1RE0 GDP 0.00000000001989 0.85053 18.2927
435 1S9D GDP 0.0000000002224 0.77144 18.2927
436 4XOI GTP 0.0000004613 0.54517 18.3333
437 1B7T ADP 0.0007353 0.45815 19.2308
438 1KK8 BEF ADP 0.001174 0.43974 19.4805
439 1TQ4 GDP 0.0000003114 0.5828 19.5122
440 1Z0A GDP 0.000000007496 0.68859 19.5402
441 2A5J GDP 0.00000002527 0.66422 19.8953
442 1Z0F GDP 0.00000001354 0.68708 20.1117
443 5SZH GNP 0.00000004268 0.56246 20.2614
444 1P9B GDP 0.00004069 0.50418 20.3252
445 2BME GNP 0.00000004326 0.57157 20.4301
446 2GJ8 ALF GDP 0.000000083 0.54862 21.5116
447 5LTJ ADP 0.0003086 0.4811 21.5447
448 4M9Q GNP 0.000000003858 0.64735 22.0264
449 3KUD GDP 0.00000000335 0.66602 22.2222
450 1GUA GNP 0.00000003305 0.56733 22.2222
451 3ZIA ATP 0.00002731 0.53088 22.2222
452 3ZIA ADP 0.00008023 0.49672 22.2222
453 1M2O GNP 0.0000001737 0.54657 22.6316
454 2V7Q ATP 0.00004506 0.51414 22.7273
455 2V7Q ADP 0.0001294 0.50525 22.7273
456 4V0K GDP 0.00000003447 0.58271 23.6686
457 4ZI2 GNP 0.000000007174 0.63672 23.6842
458 1Z0J GTP 0.0000001165 0.54673 23.7288
459 4GOJ GNP 0.000000003356 0.64983 23.8095
460 3AQ4 GDP 0.0000000002191 0.77174 24.4565
461 1FZQ GDP 0.0000000001696 0.79022 24.8619
462 2X77 GDP 0.00000002065 0.67843 25.3968
463 2QTV GNP 0.0000001655 0.558 25.7485
464 1MR3 G3D 0.000000001646 0.73035 25.9669
465 2J59 GTP 0.000000004624 0.62869 26.1905
466 5EE5 GTP 0.00000004595 0.60388 26.3158
467 1F6B GDP 0.0000000007878 0.74548 26.7677
468 1ZD9 GDP 0.0000000009355 0.69892 27.1277
469 1R4A GNP 0.00000001366 0.59881 27.8788
470 4BAS GNP 0.00000001074 0.62895 28.6432
471 1YZG GDP 0.0000000001593 0.7783 29.6089
472 3DOE GTP 0.000000002462 0.63992 29.6875
473 4KAX GTP 0.000000002429 0.65496 30.1775
474 5DI3 GNP 0.00000000586 0.64027 30.8108
475 1Z0K GTP 0.0000001037 0.5789 30.814
476 1KSH GDP 0.000000004417 0.66094 31.1828
477 4YLG GDP 0.000000002869 0.68737 31.2139
478 3WY9 GDP 0.0000000000445 0.83316 31.25
479 4D0G GTP 0.000000162 0.58249 31.8841
480 1ZC3 GNP 0.00000002469 0.57098 32.7434
481 2A5F GTP 0.000000005795 0.61085 33.1429
482 1ZJ6 G3D 0.0000000001355 0.78161 33.6898
483 2W83 GTP 0.000000003366 0.63389 34.5455
484 1J2J GTP 0.00000005612 0.58774 35.5556
485 3N5C GDP 0.0000000000467 0.81735 35.8025
486 3PCR GTP 0.0000000189 0.60584 35.8025
Pocket No.: 2; Query (leader) PDB : 3AB3; Ligand: GDP; Similar sites found: 20
This union binding pocket(no: 2) in the query (biounit: 3ab3.bio2) has 21 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3VM7 GLC 0.01839 0.40992 2.43902
2 4YMU ARG 0.01991 0.41124 2.72727
3 3LN9 FLC 0.005878 0.42505 5.03597
4 1DKU AP2 0.02198 0.40635 5.04732
5 5XQL C2E 0.03358 0.40371 5.28455
6 1X6V ADP 0.0004253 0.40225 5.28455
7 3CV2 OXL 0.02679 0.40463 5.52486
8 5M8T 0TR 0.01479 0.40956 6.62983
9 5DNC ASN 0.01934 0.40372 6.90608
10 4RF7 ARG 0.02699 0.40319 6.90608
11 3WIR BGC 0.01942 0.40876 6.91057
12 4P32 ADP 0.003443 0.40444 6.91057
13 1YXM ADE 0.01618 0.40873 7.59076
14 1D8C SOR 0.025 0.41766 7.72358
15 3ZZH ARG 0.01875 0.40038 7.81759
16 5GZ9 MAN 0.02722 0.41023 9.7561
17 3FYH ADP 0.00172 0.40318 10.2484
18 1M7G ADP 0.0003859 0.40325 12.3223
19 1DCP HBI 0.01881 0.41789 25
20 1QHH ATP 0.01541 0.40065 33.913
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