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Receptor
PDB id Resolution Class Description Source Keywords
3AXB 1.92 Å EC: 1.-.-.- STRUCTURE OF A DYE-LINKED L-PROLINE DEHYDROGENASE FROM THE A HYPERTHERMOPHILIC ARCHAEON, AEROPYRUM PERNIX AEROPYRUM PERNIX DINUCLEOTIDE-BINDING FOLD OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF NOVEL DYE-LINKED L-PROLINE DEHYDROGENASE FROM HYPERTHERMOPHILIC ARCHAEON AEROP PERNIX J.BIOL.CHEM. V. 287 20070 2012
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
EDO A:3001;
A:3002;
A:3003;
A:3004;
A:3005;
A:3006;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
submit data
62.068 C2 H6 O2 C(CO)...
FAD A:1001;
Valid;
none;
submit data
785.55 C27 H33 N9 O15 P2 Cc1cc...
PRO A:2001;
Valid;
none;
submit data
115.13 C5 H9 N O2 C1C[C...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3AXB 1.92 Å EC: 1.-.-.- STRUCTURE OF A DYE-LINKED L-PROLINE DEHYDROGENASE FROM THE A HYPERTHERMOPHILIC ARCHAEON, AEROPYRUM PERNIX AEROPYRUM PERNIX DINUCLEOTIDE-BINDING FOLD OXIDOREDUCTASE
Ref.: CRYSTAL STRUCTURE OF NOVEL DYE-LINKED L-PROLINE DEHYDROGENASE FROM HYPERTHERMOPHILIC ARCHAEON AEROP PERNIX J.BIOL.CHEM. V. 287 20070 2012
Members (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 318 families.
1 3AXB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 3VQR - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
70% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 280 families.
1 3AXB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 3VQR - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
50% Homology Family (2)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 187 families.
1 3AXB - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
2 3VQR - FAD C27 H33 N9 O15 P2 Cc1cc2c(cc....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: FAD; Similar ligands found: 128
No: Ligand ECFP6 Tc MDL keys Tc
1 FAD 1 1
2 FAS 1 1
3 FAY 0.859259 0.9875
4 RFL 0.852941 0.963855
5 6FA 0.794118 0.987654
6 FAE 0.751773 0.987654
7 SFD 0.651007 0.860215
8 FDA 0.641892 0.906977
9 FNK 0.602564 0.876405
10 62F 0.572327 0.939024
11 F2N 0.566265 0.886364
12 FMN 0.543307 0.876543
13 FA9 0.526316 0.939759
14 6YU 0.516304 0.860215
15 P6G FDA 0.511628 0.908046
16 FAD NBT 0.508876 0.83871
17 A2D 0.504065 0.875
18 P5F 0.491329 0.941176
19 FAD CNX 0.488506 0.8125
20 AR6 0.488372 0.851852
21 APR 0.488372 0.851852
22 AGS 0.484615 0.811765
23 SAP 0.484615 0.811765
24 M33 0.484375 0.864198
25 BA3 0.484127 0.875
26 HEJ 0.48062 0.851852
27 ATP 0.48062 0.851852
28 ADP 0.480315 0.851852
29 B4P 0.480315 0.875
30 AP5 0.480315 0.875
31 ANP 0.477273 0.831325
32 AQP 0.476923 0.851852
33 5FA 0.476923 0.851852
34 48N 0.469388 0.902439
35 OAD 0.467626 0.876543
36 9X8 0.467626 0.833333
37 FAD NBA 0.467033 0.793814
38 GTA 0.465753 0.892857
39 AN2 0.465116 0.841463
40 AT4 0.465116 0.821429
41 AD9 0.462121 0.831325
42 3OD 0.460993 0.876543
43 RBF 0.460938 0.790123
44 FB0 0.460606 0.835165
45 139 0.460526 0.858824
46 AP0 0.46 0.835294
47 A22 0.459854 0.864198
48 ACP 0.458015 0.853659
49 8QN 0.456522 0.864198
50 PRX 0.454545 0.831325
51 A3R 0.453237 0.86747
52 A1R 0.453237 0.86747
53 G3A 0.452055 0.902439
54 T5A 0.45098 0.872093
55 G5P 0.44898 0.902439
56 ATF 0.448529 0.821429
57 50T 0.44697 0.819277
58 6YZ 0.445255 0.853659
59 ACQ 0.444444 0.853659
60 CNV FAD 0.443182 0.917647
61 ADQ 0.442857 0.853659
62 PAJ 0.442857 0.847059
63 5AL 0.441176 0.864198
64 ADX 0.439394 0.775281
65 CA0 0.439394 0.853659
66 A4P 0.437909 0.831461
67 25L 0.4375 0.864198
68 P33 FDA 0.436464 0.817204
69 5SV 0.435714 0.793103
70 OMR 0.434211 0.818182
71 TXE 0.434211 0.890244
72 ABM 0.434109 0.829268
73 A 0.433071 0.82716
74 AMP 0.433071 0.82716
75 4AD 0.432624 0.855422
76 ADJ 0.432258 0.818182
77 B5M 0.431507 0.878049
78 B5Y 0.431507 0.878049
79 BIS 0.430556 0.802326
80 SRA 0.429688 0.788235
81 AFH 0.42953 0.825581
82 NXX 0.427632 0.865854
83 DND 0.427632 0.865854
84 UP5 0.427632 0.878049
85 6V0 0.427632 0.857143
86 TXD 0.427632 0.890244
87 DQV 0.426667 0.8875
88 SRP 0.42446 0.843373
89 PR8 0.423611 0.837209
90 T99 0.423358 0.821429
91 TAT 0.423358 0.821429
92 AMO 0.422535 0.865854
93 TXA 0.42069 0.865854
94 FYA 0.42069 0.864198
95 PTJ 0.42069 0.835294
96 CNA 0.420382 0.865854
97 00A 0.41958 0.823529
98 AHX 0.41958 0.835294
99 MAP 0.41844 0.811765
100 NAI 0.418301 0.845238
101 AU1 0.41791 0.831325
102 A12 0.416667 0.843373
103 AP2 0.416667 0.843373
104 25A 0.415493 0.851852
105 9ZA 0.415493 0.845238
106 9ZD 0.415493 0.845238
107 COD 0.415094 0.842697
108 4TC 0.412903 0.879518
109 APC 0.411765 0.843373
110 ME8 0.410959 0.806818
111 1ZZ 0.410959 0.806818
112 NB8 0.410959 0.835294
113 4UW 0.409091 0.825581
114 NAX 0.409091 0.837209
115 F2R 0.408805 0.850575
116 RBY 0.408759 0.843373
117 ADV 0.408759 0.843373
118 P1H 0.405882 0.818182
119 OOB 0.405594 0.864198
120 LAD 0.40411 0.825581
121 A A 0.40411 0.829268
122 UPA 0.403846 0.86747
123 4UU 0.401316 0.833333
124 GA7 0.401316 0.865854
125 A3D 0.401235 0.876543
126 80F 0.401235 0.808989
127 XAH 0.4 0.806818
128 DLL 0.4 0.864198
Ligand no: 2; Ligand: PRO; Similar ligands found: 3
No: Ligand ECFP6 Tc MDL keys Tc
1 PRO 1 1
2 YCP 0.769231 0.875
3 LPD 0.571429 0.722222
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 3AXB; Ligand: FAD; Similar sites found with APoc: 979
This union binding pocket(no: 1) in the query (biounit: 3axb.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
1 6CS9 PIO None
2 3GF4 FAD 1.02564
3 3GF4 UPG 1.02564
4 2YY7 NAD 1.11607
5 6C8R SAH 1.31926
6 5WP5 SAH 1.33929
7 1PN0 IPH 1.33929
8 1PN0 FAD 1.33929
9 2FR1 NDP 1.33929
10 4AZW SAM 1.33929
11 1GR0 NAD 1.3624
12 3OJO NAD 1.39211
13 5MPT SAH 1.44928
14 1DSS NAD 1.5015
15 6H45 QEI 1.53061
16 5UAV NDP 1.5528
17 5UAV TFB 1.5528
18 1X87 NAD 1.5625
19 3AYI FAD 1.5625
20 3NT6 FAD 1.5625
21 3AYI HCI 1.5625
22 3NTA FAD 1.5625
23 5UAO FAD 1.5625
24 3PT9 SAH 1.5625
25 2C7G ODP 1.5625
26 2C7G FAD 1.5625
27 1GET FAD 1.5625
28 1GET NAP 1.5625
29 1YP4 ADP 1.5625
30 5FWA J7C 1.56951
31 4UP3 FAD 1.59236
32 4UP3 NDP 1.59236
33 1P0F NAP 1.60858
34 1U2Z SAH 1.61663
35 2J5V PCA 1.63488
36 1YS4 NAP 1.69492
37 2XVF FAD 1.72414
38 2XVE FAD 1.72414
39 3H9E NAD 1.7341
40 1KOL NAD 1.75879
41 2I7C AAT 1.76678
42 3ZV6 NAD 1.77936
43 1VQW FAD 1.78571
44 2GVC FAD 1.78571
45 2GV8 FAD 1.78571
46 2A8X FAD 1.78571
47 4M52 FAD 1.78571
48 3L9W AMP 1.78571
49 3L9W GSH 1.78571
50 1E1M FAD 1.78571
51 1E1M NAP 1.78571
52 1Q9I FAD 1.78571
53 1Q9I TEO 1.78571
54 2GV8 NDP 1.78571
55 1P31 EPU 1.78571
56 4M52 M52 1.78571
57 2Q28 ADP 1.78571
58 1P3D UMA 1.78571
59 3L9W FMN 1.78571
60 4BVA NDP 1.79104
61 3KB6 NAD 1.79641
62 4D79 ATP 1.81159
63 1ZBQ NAD 1.83486
64 3NJ4 NAD 1.83908
65 3NJ4 AFX 1.83908
66 2O4C NAD 1.84211
67 3AY6 NAI 1.85874
68 5ULP KB1 1.86567
69 5G48 1FL 1.87166
70 3MN9 ATP 1.87166
71 5YPU ATP 1.90217
72 5DF1 58X 1.90217
73 5DF1 NAP 1.90217
74 5X20 NAD 1.92308
75 4DPL NAP 1.94986
76 5NA1 FAD 1.96078
77 2FJK 13P 1.96721
78 1X7D NAD 2
79 1D4D FAD 2.00893
80 1Y8Q ATP 2.00893
81 1ZK7 FAD 2.00893
82 1EBF NAD 2.00893
83 5DNK SAH 2.00893
84 5WP4 SAH 2.00893
85 1T9D P22 2.00893
86 1LDM NAD 2.00893
87 1YKJ FAD 2.00893
88 1YKJ PHB 2.00893
89 2ZWA SAH 2.00893
90 4EDF UPG 2.00893
91 1UWK NAD 2.00893
92 1UWK URO 2.00893
93 1U8X NAD 2.00893
94 3OZ2 FAD 2.01511
95 4URF NAD 2.01613
96 5Y8L NAD 2.0339
97 5Y8L HUI 2.0339
98 2GN4 UD1 2.03488
99 2YYY NAP 2.04082
100 5A1T NAI 2.05279
101 5A1T OXM 2.05279
102 4HXY NDP 2.05479
103 4MP8 NAD 2.0649
104 4MP8 MLI 2.0649
105 5A04 NDP 2.0649
106 5A04 BGC 2.0649
107 3B1F NAD 2.06897
108 1Z82 NDP 2.08955
109 2C5A NAD 2.11082
110 2C5A GDC 2.11082
111 6BQ6 TER 2.1148
112 2GCG NDP 2.12121
113 6BWL NAD 2.13415
114 5BJX UDP 2.18579
115 5BJX NAD 2.18579
116 1F06 NDP 2.1875
117 1F06 2NP 2.1875
118 3ABI NAD 2.19178
119 3OA2 NAD 2.20126
120 3X0V FAD 2.23214
121 5X68 FAD 2.23214
122 5HSA FAS 2.23214
123 4C4A SAH 2.23214
124 1O0S NAI 2.23214
125 1NVT NAP 2.23214
126 1OBB NAD 2.23214
127 5JJR SAH 2.23214
128 1QMG APX 2.23214
129 4WOE ADP 2.23214
130 5OD2 5ID 2.23214
131 1HKU NAD 2.23464
132 3DAG FEG 2.23464
133 4ZRN UPG 2.24359
134 4ZRN NAD 2.24359
135 5W7K SAH 2.24359
136 4D3F NAP 2.25806
137 5AYV NAP 2.26537
138 5AYV KPL 2.26537
139 5XH2 NPO 2.29008
140 2HQM FAD 2.29645
141 2O07 MTA 2.30263
142 2O07 SPD 2.30263
143 4W6Z 8ID 2.30548
144 1O6Z NAD 2.31023
145 6DNT NAD 2.32558
146 5YU3 NAD 2.32558
147 5YU3 PRO 2.32558
148 4XDZ NDP 2.33236
149 3MB5 SAM 2.35294
150 1GZ4 ATP 2.35935
151 6EL3 NAP 2.3622
152 2D2I NAP 2.36842
153 3I7S PYR 2.39726
154 3F9W SAH 2.40964
155 3U31 NAD 2.41379
156 2EG5 SAH 2.41935
157 4MCC 21X 2.43902
158 4NTC FAD 2.45536
159 1J0X NAD 2.45536
160 3X0D SAH 2.45536
161 2JHP SAH 2.45536
162 5TC4 NAD 2.45536
163 1GQ2 NAP 2.45536
164 5M67 ADE 2.45536
165 5M67 NAD 2.45536
166 2ZJ1 NAD 2.45536
167 2ZJ1 ARJ 2.45536
168 5M67 3D1 2.45536
169 1HDR NAD 2.45902
170 2BD0 NAP 2.45902
171 5EOW FAD 2.46914
172 5ZZO FLC 2.48756
173 1SAY PYR 2.49307
174 1V8B NAD 2.50522
175 3RGG AIR 2.51572
176 2FK8 SAM 2.51572
177 4ONQ SFG 2.52101
178 3E7S AT2 2.5522
179 5O42 BGC 2.55474
180 5O42 9JW 2.55474
181 5O42 NAD 2.55474
182 5KKA 6V0 2.5641
183 4L8F MTX 2.5641
184 1SQF SAM 2.5641
185 1GV0 NAD 2.58065
186 1NYT NAP 2.58303
187 3CBG SAH 2.58621
188 3T7S SAM 2.61194
189 4JJF FE9 2.61628
190 4JJF N2I 2.61628
191 2EB5 OXL 2.62172
192 1VM6 NAD 2.63158
193 1YJQ NAP 2.64026
194 1I36 NAP 2.65152
195 3B20 NAD 2.65487
196 4R5M NAP 2.65957
197 3ZNN 4WL 2.67857
198 3ZNN FAD 2.67857
199 3LZW FAD 2.67857
200 3AB1 FAD 2.67857
201 1COY FAD 2.67857
202 1PL6 NAD 2.67857
203 1DJN ADP 2.67857
204 3LZW NAP 2.67857
205 1RM4 NDP 2.67857
206 1COY AND 2.67857
207 1PL6 572 2.67857
208 4XFR CIT 2.67857
209 6D6Y SAH 2.67857
210 4X1B MLI 2.67857
211 3DUW SAH 2.69058
212 5X62 SAH 2.70936
213 1RKX NAD 2.80112
214 2PT9 S4M 2.80374
215 2PT9 2MH 2.80374
216 3C1O NAP 2.80374
217 1NJR XYL 2.8169
218 4CJX NAP 2.82132
219 3IP8 B85 2.82258
220 4IJ6 SEP 2.8436
221 5N0J FAD 2.849
222 5Z2L NDP 2.85714
223 1XKQ NDP 2.85714
224 4TSK NDP 2.85714
225 2DFV NAD 2.88184
226 3DMH SAM 2.88714
227 2BKX F6R 2.89256
228 2B4R NAD 2.89855
229 2B4R AES 2.89855
230 2WA2 SAM 2.89855
231 1V59 NAD 2.90179
232 5FJN FAD 2.90179
233 5FJN BE2 2.90179
234 2NVK NAP 2.90179
235 2QA1 FAD 2.90179
236 1WDK NAD 2.90179
237 4REP FAD 2.90179
238 5WGR FAD 2.90179
239 3VPH NAD 2.90179
240 2NVK FAD 2.90179
241 1V59 FAD 2.90179
242 3VPH OXM 2.90179
243 1YBH P22 2.90179
244 1CDO NAD 2.90179
245 2AQJ TRP 2.90179
246 2AQJ FAD 2.90179
247 2AHR NAP 2.90179
248 4XDA ADP 2.91262
249 4NBT NAD 2.91667
250 2IXB NAD 2.92793
251 2IXB A2G 2.92793
252 4FZV SAM 2.92887
253 3MAG SAH 2.9316
254 2P41 SAH 2.95082
255 3EF0 ALF 2.95699
256 5FUB SAH 2.96736
257 5AHO TLA 2.97619
258 2YX1 SFG 2.97619
259 3L4S NAD 2.97619
260 3L4S 3PG 2.97619
261 5D4V SAH 2.98507
262 2WD7 NAP 2.98507
263 1VDC FAD 3.003
264 4KRG SAH 3.00429
265 2CDC XYP 3.00546
266 2CDC XYS 3.00546
267 2CDC NAP 3.00546
268 1KYZ SAH 3.0137
269 2XVM SAH 3.01508
270 1CER NAD 3.02115
271 3MCT SAH 3.0303
272 3W6X HZP 3.05677
273 4IWN GEK 3.05677
274 1U7T NAD 3.06513
275 1U7T TDT 3.06513
276 1KJ8 GAR 3.06905
277 5Z21 NAI 3.07263
278 2AOT SAH 3.08219
279 3VZS NAP 3.11284
280 1PJS NAD 3.125
281 3SQP FAD 3.125
282 4IV9 FAD 3.125
283 2GMH FAD 3.125
284 5BUK FAD 3.125
285 3E1T FAD 3.125
286 1YKF NAP 3.125
287 2O2C G6Q 3.125
288 1EZ4 NAD 3.14465
289 1XTP SAI 3.14961
290 5UR0 NAD 3.15186
291 1WPQ NAD 3.15186
292 1WG8 SAM 3.15789
293 1EK6 UPG 3.16092
294 1EK6 NAI 3.16092
295 1TDF NAP 3.16456
296 1TDF FAD 3.16456
297 2G5C NAD 3.20285
298 1U3U NAD 3.20856
299 1U3U BNF 3.20856
300 3G89 SAM 3.21285
301 2UYQ SAM 3.22581
302 2VT3 ATP 3.25581
303 1R6D NAD 3.2641
304 1R6D DAU 3.2641
305 4GLL NAD 3.2641
306 3WBF NAP 3.27869
307 3WBF API 3.27869
308 6CEP NAD 3.29341
309 6CEP OXM 3.29341
310 3CMC NAD 3.29341
311 4Z0H NAD 3.29341
312 4KOA NDP 3.3033
313 4DMG SAM 3.30789
314 1W8D NAP 3.31126
315 1W73 NAP 3.31126
316 1W6U NAP 3.31126
317 1V6A TRE 3.31325
318 1HDG NAD 3.31325
319 9LDT NAD 3.31325
320 9LDB NAD 3.31325
321 2GLX NDP 3.31325
322 2VYN NAD 3.32326
323 1KEW NAD 3.3241
324 1KEW TYD 3.3241
325 1GAD NAD 3.33333
326 1WVG APR 3.34262
327 3BXO SAM 3.34728
328 5G3U FDA 3.34821
329 5G3U ITW 3.34821
330 4CNK FAD 3.34821
331 2CDU FAD 3.34821
332 5JCA FAD 3.34821
333 1BXK NAD 3.34821
334 2CDU ADP 3.34821
335 1DIG NAP 3.34821
336 5JCA NDP 3.34821
337 1LCF OXL 3.34821
338 5U8U FAD 3.34821
339 3S1S SAH 3.34821
340 2PV7 NAD 3.3557
341 2OFW ADX 3.36538
342 3O7W SAM 3.40136
343 2OQ2 A3P 3.44828
344 3WGT FAD 3.45821
345 3WGT QSC 3.45821
346 1R37 NAD 3.45821
347 4RQU NAD 3.46667
348 5E4R NAP 3.46939
349 2JHF NAD 3.47594
350 5TWB FAD 3.48837
351 1G6H ADP 3.50195
352 4NOS ITU 3.51288
353 4LWP SAH 3.53261
354 3GCZ SAM 3.5461
355 1EQ2 NAP 3.54839
356 2GZ3 NAP 3.55191
357 3V1Y NAD 3.56083
358 5BRT FAD 3.57143
359 3UCL NAP 3.57143
360 3SSO SAH 3.57143
361 5EB4 FAD 3.57143
362 5BRT CH9 3.57143
363 1FEC FAD 3.57143
364 1Q19 SSC 3.57143
365 4DSG FAD 3.57143
366 4DSG UDP 3.57143
367 3ETG GLU 3.57143
368 3ETG NDP 3.57143
369 4XQC NAD 3.57143
370 5AOV NAP 3.57143
371 3ETG GTP 3.57143
372 5JCM FAD 3.57143
373 3UCL CYH 3.57143
374 3UCL FAD 3.57143
375 5JCM ISD 3.57143
376 5JCM NAD 3.57143
377 4XQC 13D 3.57143
378 1C0I BE2 3.58127
379 1C0I FAD 3.58127
380 2F1K NAP 3.58423
381 5H81 NAP 3.59897
382 1J49 NAD 3.6036
383 2NU8 COA 3.60825
384 3EVG SAH 3.63636
385 5FI3 NAP 3.64146
386 1BW9 NAD 3.65169
387 1BXG NAD 3.65169
388 1C1X NAD 3.66197
389 4XZ3 COA 3.66379
390 5N6C NAD 3.66667
391 2I3G NAP 3.69318
392 1SC6 NAD 3.71287
393 4TQG NDP 3.71517
394 2ZFU SAH 3.72093
395 5DWQ SFG 3.72493
396 5DX0 SFG 3.72493
397 5DX1 SFG 3.72493
398 5DXA SFG 3.72493
399 5DX8 SFG 3.72493
400 6ARJ BW4 3.72493
401 6ARJ SAH 3.72493
402 3TWO NDP 3.73563
403 5CUQ NSC 3.74532
404 5L95 AMP 3.75
405 1D1T NAD 3.75335
406 2DT5 NAD 3.79147
407 4TXI FAD 3.79464
408 2IZ1 ATR 3.79464
409 4RPL 3UC 3.79464
410 4RPL FAD 3.79464
411 1VJT NAD 3.79464
412 2VHW NAI 3.79464
413 3OND ADN 3.79464
414 3OND NAD 3.79464
415 5TOW NAI 3.79464
416 5TOW ADN 3.79464
417 1UDB NAD 3.79464
418 1UDB UFG 3.79464
419 1F8F NAD 3.79464
420 2GJP MAL 3.79464
421 6ECU SAH 3.79747
422 5FA5 MTA 3.81471
423 1KPG SAH 3.83275
424 5CAE COA 3.83387
425 5CAE SIN 3.83387
426 5ZZ6 ADP 3.84615
427 5ZZ6 NAD 3.84615
428 3O9Z NAD 3.84615
429 3O9Z AKG 3.84615
430 1Q0S SAH 3.861
431 1WY7 SAH 3.86473
432 4GKV NAD 3.86905
433 1L5Y BEF 3.87097
434 3GU3 SAH 3.87324
435 2PWY SAH 3.87597
436 3AFN NAP 3.87597
437 1EJ0 SAM 3.88889
438 4MDH NAD 3.89222
439 4EMI FAD 3.90244
440 4EMI NAD 3.90244
441 5MDH NAD 3.9039
442 5KOH HCA 3.91389
443 4ZVV GN0 3.91566
444 4ZVV NAD 3.91566
445 1I2B NAD 3.9604
446 1I2B USQ 3.9604
447 1I2B UPG 3.9604
448 2RH4 EMO 3.97112
449 1RYO OXL 3.97554
450 1I1N SAH 3.9823
451 3NGL NAP 3.98551
452 2CFC NAD 4
453 1GPE FAD 4.01786
454 4B4U NAP 4.01786
455 2IVD FAD 4.01786
456 2E5V FAD 4.01786
457 2RGJ FAD 4.01786
458 4HA6 FAD 4.01786
459 3GDN FAD 4.01786
460 1BZL FAD 4.01786
461 3GDN HBX 4.01786
462 4N49 SAM 4.01786
463 4D86 ADP 4.01786
464 1GTE FAD 4.01786
465 3HAD NAD 4.01786
466 2IVD ACJ 4.01786
467 1BZL GCG 4.01786
468 3H4V NAP 4.01786
469 3TLJ SAH 4.02145
470 1ORR NAD 4.03458
471 5GM1 SAH 4.0404
472 3NUG NAD 4.04858
473 4GQB 0XU 4.06977
474 1NW5 SAM 4.07523
475 1GZ6 NAI 4.07523
476 4M37 SAH 4.08163
477 4M38 SAH 4.08163
478 3WLE NAD 4.10557
479 5EVY FAD 4.10959
480 2GDZ NAD 4.11985
481 3RFV 15L 4.11985
482 3RFV NAI 4.11985
483 3KO8 NAD 4.16667
484 5IFK HPA 4.16667
485 5TVA AMP 4.16667
486 1L1E SAH 4.18118
487 6FDF SAH 4.19162
488 3K5I AIR 4.21836
489 5Y77 FAD 4.22833
490 2BRY FAD 4.24107
491 2R4J 13P 4.24107
492 2R4J FAD 4.24107
493 1MO9 KPC 4.24107
494 1MO9 FAD 4.24107
495 1KNR FAD 4.24107
496 3S5W FAD 4.24107
497 3S5W NAP 4.24107
498 1H82 FAD 4.24107
499 2NPX FAD 4.24107
500 3HDY FAD 4.24107
501 3HDY FDA 4.24107
502 3HDY GDU 4.24107
503 1H82 GZZ 4.24107
504 1Z45 NAD 4.24107
505 1OC2 TDX 4.24107
506 1OC2 NAD 4.24107
507 2NPX NAD 4.24107
508 1VKO NAD 4.24107
509 5K4W NAI 4.24107
510 5K4W THR 4.24107
511 1RM0 D6P 4.24107
512 1RM0 NAI 4.24107
513 3VY6 BGC BGC 4.25532
514 2RI1 GLP 4.25532
515 1SB8 UD2 4.26136
516 1SB8 NAD 4.26136
517 1L7N ALF 4.2654
518 1UP7 NAD 4.31655
519 4MO2 FDA 4.34783
520 4MO2 FAD 4.34783
521 4XYB NDP 4.34783
522 1DRV A3D 4.3956
523 3T64 DU3 4.41989
524 2YPI PGA 4.45344
525 3QOX SAH 4.46009
526 1LVL NAD 4.46429
527 5BVA FAD 4.46429
528 4MOP 2H5 4.46429
529 3K7M FAD 4.46429
530 1LVL FAD 4.46429
531 5YB7 ORN 4.46429
532 5YB7 FAD 4.46429
533 4J1Q NDP 4.46429
534 1KXP ATP 4.46429
535 2JJQ SAH 4.47059
536 1DLJ NAI 4.47761
537 1DLJ UGA 4.47761
538 3QH2 3NM 4.52489
539 4EUE NAI 4.54545
540 4EA7 JB2 4.54545
541 4EA7 COA 4.54545
542 4XUC 43G 4.58716
543 4XUC SAM 4.58716
544 3MQ2 SAH 4.58716
545 3JWH SAH 4.60829
546 4KRI SAH 4.61894
547 5JE8 NAD 4.63576
548 1YQD NAP 4.64481
549 1OMO NAD 4.65839
550 2DC1 NAD 4.66102
551 3LU1 NAD 4.67033
552 4EMJ FAD 4.6729
553 3ULK NDP 4.68432
554 5JWC FAD 4.6875
555 1I8T FAD 4.6875
556 4YNU FAD 4.6875
557 4MIG G3F 4.6875
558 4YNU LGC 4.6875
559 5O4J PJL 4.6875
560 5O4J 9KH 4.6875
561 4U8P FDA 4.6875
562 5O4J SAH 4.6875
563 4U8P UDP 4.6875
564 2EFJ SAH 4.6875
565 3SJ7 NDP 4.6875
566 1I1Q TRP 4.6875
567 6GNF ADP 4.6875
568 5VKT NAP 4.69613
569 6F97 FAD 4.7081
570 5LOG SAH 4.72103
571 4XDY NAI 4.73373
572 4AP3 NAP 4.73588
573 4AP3 FAD 4.73588
574 1CF2 NAP 4.74777
575 1E3I CXF 4.78723
576 3HCH RSM 4.79452
577 3FUU ADN 4.79705
578 2FN1 SAL 4.80549
579 5W7M SAH 4.80769
580 1WP4 NDP 4.84429
581 2CVZ NDP 4.84429
582 5EES NAP 4.8583
583 5ZW3 SAH 4.88889
584 1H5Q NAP 4.90566
585 5MBX FAD 4.91071
586 5MBX SP5 4.91071
587 1REO FAD 4.91071
588 5TS5 FAD 4.91071
589 1RP0 AHZ 4.91071
590 5KOX FAD 4.91071
591 4D04 FAD 4.91071
592 4D04 NAP 4.91071
593 4L8V NAP 4.91071
594 5MZI FAD 4.91071
595 2CVQ NDP 4.91071
596 5MZI FYK 4.91071
597 5KOX RFP 4.91071
598 2X6T NAP 4.91071
599 2V7B BEZ 4.91071
600 3D3W NAP 4.91803
601 1PR9 NAP 4.91803
602 5OFW 9TW 4.93274
603 3A25 SAM 4.98339
604 5MB4 NAG 4.98753
605 1G60 SAM 5
606 1K3T BRZ 5.01393
607 1M0S CIT 5.02283
608 3NKS FAD 5.03145
609 1GY8 NAD 5.03778
610 1RSG FAD 5.03876
611 4R6W SAH 5.03876
612 1DL5 SAH 5.04732
613 5F1V 3VN 5.05051
614 4ZCC FAD 5.05952
615 4ZCC NAI 5.05952
616 1YY5 FAD 5.06823
617 4CVN ADP 5.10949
618 5XNC MTA 5.12129
619 4J36 1HR 5.13393
620 2WPF WPF 5.13393
621 2WPF FAD 5.13393
622 1PS9 FAD 5.13393
623 1PS9 NAP 5.13393
624 2IID PHE 5.13393
625 2IID FAD 5.13393
626 4J36 FAD 5.13393
627 6F3M NAD 5.13393
628 6F3N ADN 5.13393
629 6F3N NAD 5.13393
630 2Q0L NAP 5.14469
631 2Q0L FAD 5.14469
632 2BZG SAH 5.17241
633 3VYW SAM 5.19481
634 5KVS NAP 5.19481
635 1L7E NAI 5.20833
636 1TPY SAH 5.22648
637 3C6K SPD 5.24934
638 3C6K MTA 5.24934
639 6AIN FAD 5.26316
640 4JDR FAD 5.27426
641 3CIF NAD 5.29248
642 3CIF G3H 5.29248
643 6ECT SAM 5.29595
644 1C3V NDP 5.30612
645 1O94 ADP 5.3125
646 4KIB SAH 5.32213
647 1ZEM NAD 5.34351
648 5MLR NAP 5.3528
649 5MLR GRQ 5.3528
650 3FPZ AHZ 5.35714
651 4TM3 FAD 5.35714
652 1LDN NAD 5.35714
653 5EE7 5MV 5.35714
654 1U1I NAD 5.35714
655 3F8D FAD 5.35714
656 2A40 ATP 5.38462
657 5HJM MTA 5.39773
658 4JK3 NAD 5.40541
659 4J4H NAI 5.40541
660 4J4H 1J1 5.40541
661 6BII NAP 5.40541
662 3GFB NAD 5.42857
663 3KLJ FAD 5.45455
664 2FWP CIT 5.46448
665 2FWP ICR 5.46448
666 5DN9 NAD 5.49451
667 4CBX ATP 5.51181
668 1P77 ATR 5.51471
669 2YG3 FAD 5.51876
670 3VSE SAH 5.52764
671 2EJU SAH 5.55556
672 1JNR FAD 5.58036
673 2DKH FAD 5.58036
674 2VVM FAD 5.58036
675 2DKH 3HB 5.58036
676 2VVL FAD 5.58036
677 2JB2 FAD 5.58036
678 2JB2 PHE 5.58036
679 2YLN CYS 5.58036
680 2ZIF SAM 5.58036
681 5JY6 NAD 5.58036
682 4DCM SAM 5.6
683 1ZGA SAH 5.60224
684 3KYF 5GP 5GP 5.62771
685 5N53 8NB 5.64103
686 3G5S FAD 5.64334
687 5O9F 9ON 5.68182
688 5O9F NAD 5.68182
689 3G2O SAM 5.68562
690 4OOE NDP 5.69307
691 3BAZ NAP 5.70571
692 1LSS NAD 5.71429
693 5DQY BEZ 5.71429
694 5NUF NAD 5.72289
695 5NUE NAD 5.72289
696 1QAN SAH 5.7377
697 5E9W SAH 5.76923
698 3IHG FAD 5.79439
699 1Q1R FAD 5.80046
700 5YF1 SFG 5.80111
701 5YF1 8V0 5.80111
702 4OPC PGT 5.80357
703 4OPC FDA 5.80357
704 5ZBC FAD 5.80357
705 2XYQ SAH 5.80357
706 2Q1S NAI 5.80357
707 1VCO GLN 5.80357
708 1ZPD DPX 5.80357
709 2HK9 ATR 5.81818
710 2HK9 NAP 5.81818
711 1NE7 AGP 5.88235
712 1EX7 5GP 5.91398
713 3LKZ SFG 5.919
714 1LUA NAP 5.92335
715 3WV8 ATP 5.9633
716 4X7G NAP 5.9761
717 1KEV NDP 5.98291
718 2Q1W NAD 6.00601
719 1C3X 8IG 6.01504
720 2WOE AR6 6.02007
721 2ZXI FAD 6.02679
722 2PXX SAH 6.04651
723 5OKT 9XK 6.05096
724 5E72 SAM 6.06936
725 1UZN NAP 6.07287
726 5ZI2 NAD 6.08696
727 5ZI2 ADP 6.08696
728 3VC1 SAH 6.08974
729 4USR FAD 6.09418
730 3H8V ATP 6.16438
731 5EJ2 NAD 6.16883
732 1RJW ETF 6.19469
733 1KYQ NAD 6.20438
734 3NHB ADP 6.20915
735 1F3L SAH 6.23053
736 2C29 NAP 6.23145
737 1E6E FAD 6.25
738 3QJ4 FAD 6.25
739 3ITJ CIT 6.25
740 3ITJ FAD 6.25
741 5OVK NDP 6.25
742 4RF7 ARG 6.25
743 4IF4 BEF 6.25
744 1N2X SAM 6.31229
745 1NM5 NAD 6.40394
746 3GRU AMP 6.44068
747 1ZH8 NAP 6.47059
748 4R78 AMP 6.47249
749 1HYH NAD 6.47249
750 4C3Y FAD 6.47321
751 2F5Z FAD 6.47321
752 4C3Y ANB 6.47321
753 1E5Q NDP 6.47321
754 5J5Z FAD 6.47321
755 4POO SAM 6.5
756 1F8G NAD 6.51042
757 1P9P SAH 6.51341
758 4YUW 4JU 6.57895
759 4YUW S4M 6.57895
760 1A5Z NAD 6.58307
761 3MMH SME 6.58683
762 4RDH AMP 6.59722
763 4RDI ATP 6.59722
764 3JQA NAP 6.59722
765 3JQ7 NAP 6.59722
766 3BMO NAP 6.59722
767 3JQF NAP 6.59722
768 3BMQ NAP 6.59722
769 3BMN NAP 6.59722
770 3JQ9 NAP 6.59722
771 4CM4 NAP 6.59722
772 4CM8 NAP 6.59722
773 4CM9 NAP 6.59722
774 4CMI NAP 6.59722
775 3JQG NAP 6.59722
776 3JQ8 NAP 6.59722
777 4CLR NAP 6.59722
778 3JQB NAP 6.59722
779 4PNE SAH 6.62252
780 4J56 FAD 6.65434
781 3QWI NAP 6.66667
782 5GWX SAR 6.69014
783 5GWX SAM 6.69014
784 2Y6Q FAD 6.69643
785 4USQ FAD 6.69643
786 5ZYN FAD 6.69643
787 5TUF FAD 6.69643
788 5TUF TDC 6.69643
789 6FP4 FAD 6.69643
790 2Y6Q I7T 6.69643
791 5ERG SAM 6.69643
792 6FP4 E1T 6.69643
793 1Z3C SA8 6.71141
794 2Q7V FAD 6.76923
795 1JG3 ADN 6.80851
796 1FP2 SAH 6.81818
797 3O03 NAP 6.87285
798 1MV8 NAD 6.88073
799 1MUU NAD 6.88073
800 2OOR NAD 6.89655
801 1E3W NAD 6.89655
802 3GFS FMN 6.89655
803 1E6W NAD 6.92308
804 5ZI9 FLC 6.92308
805 2YY8 MTA 6.96517
806 4CQM NAP 6.96721
807 5KXE 6Y2 6.99588
808 1LLU NAD 7.01754
809 1GEG NAD 7.03125
810 1XHL NDP 7.07071
811 4BJZ P3A 7.07547
812 4BJZ FAD 7.07547
813 5N5D SAM 7.07965
814 1JQ3 AAT 7.09459
815 3LAD FAD 7.14286
816 4EIP FAD 7.14286
817 5BW4 SAM 7.14286
818 4EIP K2C 7.14286
819 6AA8 NAD 7.14286
820 4NEC SAH 7.19697
821 1LTH NAD 7.21003
822 1USI PHE 7.22543
823 3LCC SAH 7.23404
824 1H2B NAJ 7.24234
825 6GAS FAD 7.25076
826 1L3I SAH 7.29167
827 3BGD SAH 7.30769
828 3BGD PM6 7.30769
829 3A27 SAM 7.35294
830 4JNA FAD 7.36607
831 5Z20 NAI 7.36607
832 5MIT NAP 7.36607
833 5MIT FAD 7.36607
834 1FWV SGA MAG FUC 7.46269
835 4YCA NDP 7.48299
836 1UJ5 5RP 7.48899
837 1R18 SAH 7.48899
838 1YQZ FAD 7.53425
839 4J5R A1R 7.53425
840 2YVJ NAI 7.59804
841 2YVJ FAD 7.59804
842 2YVF FAD 7.59804
843 2YVF NAD 7.59804
844 5THY SAH 7.65432
845 5THZ SAH 7.65432
846 2VOH CIT 7.69231
847 6F9Q NAD 7.72059
848 1NAA 6FA 7.8125
849 1NAA ABL 7.8125
850 2PZM UDP 7.8125
851 2PZM NAD 7.8125
852 6B74 BEN 7.81893
853 3LA3 2FT 7.81893
854 1WOQ BGC 7.86517
855 3H2B SAH 7.88177
856 4YMH SAH 7.91667
857 3ORF NAD 7.96813
858 1P1C SAH 8.0402
859 5KOK SAH 8.06045
860 2DBZ NAP 8.08383
861 4QTU SAM 8.14815
862 5GZ6 NDP 8.28221
863 5GZ6 7C3 8.28221
864 5C2N NAG 8.33333
865 5LD5 NAD 8.37989
866 3FG2 FAD 8.41584
867 4II2 ATP 8.43373
868 1Y4Z PCI 8.44444
869 2DPM SAM 8.4507
870 1QO8 FAD 8.48214
871 5TUK FAD 8.48214
872 5F8F SFG 8.48806
873 1JAY NAP 8.49057
874 4OBW SAM 8.56031
875 4U00 ADP 8.60656
876 3RNM FAD 8.62069
877 4YKG FAD 8.63724
878 4YKG NAD 8.63724
879 5NM7 GLY 8.64662
880 3NTD FAD 8.67257
881 1NVM NAD 8.69565
882 4AT0 FAD 8.70536
883 3OFK SAH 8.7963
884 1SOW NAD 8.84146
885 1GUZ NAD 9.03226
886 4YSX FAD 9.04255
887 2FZW NAD 9.11528
888 5OC1 FAD 9.20354
889 3KIH GDL 9.27835
890 3OID NDP 9.30233
891 2VDV SAM 9.34959
892 1XCL SAH 9.3617
893 5YEC ATP 9.375
894 2CDN ADP 9.45274
895 3RKR NAP 9.54198
896 5YEE ATP 9.55882
897 2RBK VN4 9.57854
898 5T9E NAP 9.5941
899 1PZG A3D 9.66767
900 5JE0 AZ8 9.7166
901 5JE0 SAH 9.7166
902 1TKU 5RP 9.80392
903 3H5N ATP 9.91501
904 5ODQ FAD 10
905 5ODQ 9SB 10
906 2NSJ C2R 10.0592
907 3V1U NAD 10.1732
908 2DKN NAI 10.1961
909 2NXE SAM 10.2362
910 5G6U TRP 10.3448
911 1UXG NAD 10.356
912 1UXG FUM 10.356
913 3Q3C NAD 10.3679
914 1LK7 DER 10.4803
915 3GGO NAI 10.5096
916 3GGO ENO 10.5096
917 5KMS FAD 10.6173
918 5KMS NAD 10.6173
919 1AE1 NAP 10.6227
920 2EV9 SKM 10.6464
921 2EV9 NAP 10.6464
922 1X14 NAD 10.7232
923 2A92 NAI 10.9375
924 1T26 NAI 10.9375
925 1T26 GBD 10.9375
926 4PL8 ATP 10.9589
927 3C3Y SAH 10.9705
928 3QV1 NAD 10.9756
929 3QFA FAD 11.2069
930 1Z0N BCD 11.4583
931 3QVP FAD 11.6071
932 1FL2 FAD 11.6129
933 5A96 GTP 11.6466
934 1I9G SAM 11.7857
935 2HMT NAI 11.8056
936 1J5P NAD 11.8577
937 1KUJ MMA 12.0301
938 5KVA SAM 12.2302
939 1ZQ9 SAM 12.2807
940 3DXY SAM 12.3853
941 1FK8 NAD 12.4514
942 3A06 NDP 12.5
943 2HNK SAH 12.5523
944 1VI2 NAD 12.6667
945 2DX7 CIT 12.7193
946 3A4T SFG 12.7737
947 5EZ7 FAD 13.0102
948 6F5Z SAH 13.1148
949 2RGO FAD 13.1696
950 2RGH FAD 13.1696
951 2FKA BEF 13.1783
952 1NPD NAD 13.1944
953 3GDH SAH 13.278
954 6GAR FAD 13.7536
955 1QH9 LAC 13.7931
956 1IM8 SAI 13.9344
957 1G55 SAH 14.2857
958 4JAL SAH 14.3713
959 5N2I NAP 14.6552
960 2FF6 ATP 15.3846
961 2HYR BGC GLC 15.5738
962 2GUE NAG 15.5738
963 3FGZ BEF 15.625
964 2PBD ATP 15.8273
965 3B1J NAD 16
966 3AD8 NAD 16.1616
967 3AD8 FAD 16.1616
968 3AD8 PYC 16.1616
969 5I39 FAD 16.9118
970 3EGI ADP 17.9612
971 2VTD LKM 18.5268
972 4OGQ 7PH 18.9189
973 4RSL FAD 21.573
974 5E8J SAH 22.7273
975 1RYI FAD 25.3927
976 1RYI GOA 25.3927
977 1ELI PYC 25.7069
978 3NYC FAD 28.084
979 3NYC IAR 28.084
Pocket No.: 2; Query (leader) PDB : 3AXB; Ligand: FAD; Similar sites found with APoc: No similar binding sites found, or similarity not calculated due to duplicate pocket.
This union binding pocket(no: 2) in the query (biounit: 3axb.bio1) has 42 residues
No: Leader PDB Ligand Sequence Similarity
Pocket No.: 3; Query (leader) PDB : 3AXB; Ligand: PRO; Similar sites found with APoc: 949
This union binding pocket(no: 3) in the query (biounit: 3axb.bio1) has 46 residues
No: Leader PDB Ligand Sequence Similarity
1 6CS9 PIO None
2 3GF4 FAD 1.02564
3 3GF4 UPG 1.02564
4 2YY7 NAD 1.11607
5 6C8R SAH 1.31926
6 1PN0 IPH 1.33929
7 1PN0 FAD 1.33929
8 5WP5 SAH 1.33929
9 2FR1 NDP 1.33929
10 4AZW SAM 1.33929
11 1GR0 NAD 1.3624
12 3OJO NAD 1.39211
13 5MPT SAH 1.44928
14 1DSS NAD 1.5015
15 6H45 QEI 1.53061
16 5UAV NDP 1.5528
17 5UAV TFB 1.5528
18 3AYI FAD 1.5625
19 3AYI HCI 1.5625
20 1X87 NAD 1.5625
21 3NT6 FAD 1.5625
22 3NTA FAD 1.5625
23 5UAO FAD 1.5625
24 3PT9 SAH 1.5625
25 2C7G ODP 1.5625
26 2C7G FAD 1.5625
27 1GET FAD 1.5625
28 1GET NAP 1.5625
29 1YP4 ADP 1.5625
30 5FWA J7C 1.56951
31 4UP3 FAD 1.59236
32 4UP3 NDP 1.59236
33 1QDS PGA 1.59363
34 1P0F NAP 1.60858
35 1U2Z SAH 1.61663
36 2J5V PCA 1.63488
37 2IYA UDP 1.65094
38 1YS4 NAP 1.69492
39 2XVF FAD 1.72414
40 2XVE FAD 1.72414
41 3H9E NAD 1.7341
42 2GSD NAD 1.74129
43 1KOL NAD 1.75879
44 2I7C AAT 1.76678
45 3ZV6 NAD 1.77936
46 1VQW FAD 1.78571
47 2GVC FAD 1.78571
48 2GV8 FAD 1.78571
49 2A8X FAD 1.78571
50 4M52 FAD 1.78571
51 3L9W AMP 1.78571
52 1E1M NAP 1.78571
53 1E1M FAD 1.78571
54 1Q9I TEO 1.78571
55 1Q9I FAD 1.78571
56 3L9W GSH 1.78571
57 2GV8 NDP 1.78571
58 1