Receptor
PDB id Resolution Class Description Source Keywords
3B1V 1.85 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF AN S. THERMOPHILUS NFEOB E67A MUTANT BO MGMPPNP STREPTOCOCCUS THERMOPHILUS G PROTEIN IRON TRANSPORT GTPASE TRANSMEMBRANE POTASSIUMTRANSPORT
Ref.: A SUITE OF SWITCH I AND SWITCH II MUTANT STRUCTURES G-PROTEIN DOMAIN OF FEOB ACTA CRYSTALLOGR.,SECT.D V. 67 973 2011
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
CL A:302;
Invalid;
none;
submit data
35.453 Cl [Cl-]
GGM A:300;
Valid;
none;
submit data
655.343 C18 H24 N7 O14 P3 CNc1c...
MG A:301;
Part of Protein;
none;
submit data
24.305 Mg [Mg+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
4NON 2.5 Å NON-ENZYME: TRANSPORT CRYSTAL STRUCTURE OF GDP-BOUND A143S MUTANT OF THE S. THERMO FEOB G-DOMAIN STREPTOCOCCUS THERMOPHILUS G PROTEIN IRON TRANSPORT GTPASE TRANSMEMBRANE METAL TRANGTP BINDING
Ref.: STRUCTURAL AND FUNCTIONAL ANALYSIS OF A FEOB A143S MUTANT EXPLAINS THE ACCELERATED GDP RELEASE RATE. FEBS J. V. 281 2254 2014
Members (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 199 families.
1 3B1V - GGM C18 H24 N7 O14 P3 CNc1ccccc1....
2 4NON Kd = 5.71 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3B1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 3B1Y - GNH C10 H16 N6 O10 P2 c1nc2c(n1[....
5 3TAH - BGO C18 H22 N6 O12 P2 CNc1ccccc1....
6 3LX5 - AGO C18 H22 N7 O14 P3 CNc1ccccc1....
70% Homology Family (6)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 166 families.
1 3B1V - GGM C18 H24 N7 O14 P3 CNc1ccccc1....
2 4NON Kd = 5.71 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3B1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 3B1Y - GNH C10 H16 N6 O10 P2 c1nc2c(n1[....
5 3TAH - BGO C18 H22 N6 O12 P2 CNc1ccccc1....
6 3LX5 - AGO C18 H22 N7 O14 P3 CNc1ccccc1....
50% Homology Family (5)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 141 families.
1 3B1V - GGM C18 H24 N7 O14 P3 CNc1ccccc1....
2 4NON Kd = 5.71 uM GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
3 3B1W - GDP C10 H15 N5 O11 P2 c1nc2c(n1[....
4 3B1Y - GNH C10 H16 N6 O10 P2 c1nc2c(n1[....
5 3TAH - BGO C18 H22 N6 O12 P2 CNc1ccccc1....
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: GGM; Similar ligands found: 68
No: Ligand ECFP6 Tc MDL keys Tc
1 GGM 1 1
2 BGO 0.895238 0.975
3 AGO 0.677686 0.9875
4 GNP 0.618182 0.925926
5 G3D 0.575221 0.9125
6 G4P 0.565217 0.9125
7 0O2 0.546219 0.9125
8 GDP 0.517544 0.901235
9 GNH 0.513043 0.91358
10 GP3 0.508772 0.925926
11 GSP 0.508475 0.858824
12 DBG 0.507143 0.950617
13 GTP 0.504274 0.901235
14 Y9Z 0.492063 0.840909
15 G1R 0.487395 0.91358
16 GCP 0.487395 0.879518
17 3GP 0.482143 0.876543
18 GMV 0.478992 0.879518
19 G2R 0.475806 0.869048
20 G 0.473684 0.888889
21 5GP 0.473684 0.888889
22 GDX 0.473282 0.925926
23 GTG 0.465116 0.939024
24 GAV 0.463415 0.869048
25 G2P 0.459016 0.869048
26 GDP MG 0.458333 0.835294
27 GDD 0.457364 0.914634
28 GDC 0.457364 0.914634
29 GKE 0.457364 0.914634
30 G G 0.456693 0.890244
31 GDP AF3 0.456 0.806818
32 JB3 0.455882 0.926829
33 JB2 0.454545 0.938272
34 GDP BEF 0.454545 0.816092
35 GFB 0.453846 0.938272
36 GDR 0.453846 0.938272
37 GP2 0.453782 0.869048
38 GMP 0.453704 0.792683
39 NGD 0.452555 0.914634
40 GPD 0.451128 0.904762
41 YGP 0.449612 0.860465
42 GPG 0.448819 0.914634
43 G5P 0.44697 0.925926
44 CAG 0.443662 0.906977
45 GKD 0.443609 0.914634
46 GTP MG 0.443548 0.835294
47 BEF GDP 0.443548 0.806818
48 ALF 5GP 0.442623 0.806818
49 FEG 0.442029 0.883721
50 DGI 0.441667 0.857143
51 GCP G 0.44 0.845238
52 6CK 0.439394 0.892857
53 G3A 0.439394 0.925926
54 GPX 0.436508 0.876543
55 GDP ALF 0.433071 0.806818
56 G G U 0.432836 0.91358
57 GH3 0.432 0.901235
58 2GP 0.431034 0.888889
59 ZGP 0.428571 0.852273
60 DGT 0.427419 0.857143
61 GDP 7MG 0.425373 0.914634
62 MD1 0.412162 0.831461
63 CG2 0.405594 0.870588
64 2MD 0.402778 0.831461
65 G G G RPC 0.402778 0.857143
66 U2G 0.401408 0.870588
67 G A A A 0.4 0.879518
68 P2G 0.4 0.841463
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 4NON; Ligand: GDP; Similar sites found: 395
This union binding pocket(no: 1) in the query (biounit: 4non.bio1) has 28 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 1GXU 2HP 0.0002353 0.52601 None
2 5GOE GDP 0.00000002343 0.68301 1.15385
3 1M7G ADX 0.0005635 0.43882 1.89573
4 1M7G ADP 0.0005474 0.43622 1.89573
5 1M7G AV2 0.00000411 0.4234 1.89573
6 4PX9 ADP 0.0001636 0.51886 1.92308
7 1P72 ADP 0.001688 0.42133 1.92308
8 2Y65 ADP 0.000001239 0.40489 1.92308
9 4ZKD GDP 0.0000001119 0.57141 2.30769
10 5IRR GSP 0.000002033 0.55675 2.30769
11 4ZNL BEF ADP 0.00009553 0.51743 2.30769
12 3EC1 GDP 0.00000003735 0.50466 2.30769
13 4QOS ADP 0.0005215 0.47628 2.30769
14 2IYL GDP 0.000004219 0.43713 2.30769
15 2J0V GDP 0.000000008925 0.51595 2.35849
16 2CBZ ATP 0.0000158 0.59405 2.53165
17 5BXV MGP 0.01424 0.43094 2.60417
18 2RCN GDP 0.0000000002283 0.551 2.69231
19 4D81 ADP 0.0002777 0.484 2.69231
20 4IEE AGS 0.001603 0.46821 2.69231
21 5L3W GDP 0.00002232 0.42914 2.69231
22 3R7F CP 0.02511 0.4128 2.69231
23 1IHU AF3 0.0003471 0.41808 2.71647
24 1IHU ADP 0.0004792 0.41808 2.71647
25 1G3Q ADP 0.00008544 0.40646 2.95359
26 3MD0 GDP 0.000000001225 0.51254 3.07692
27 5GJC ATP 0.0003988 0.49298 3.07692
28 1FNN ADP 0.001666 0.43953 3.07692
29 1V8K ANP 0.00001881 0.41539 3.07692
30 4RZ3 ADP 0.0001818 0.40986 3.07692
31 1NJF AGS 0.001156 0.40004 3.2
32 4AG5 ADP 0.00001597 0.58621 3.46154
33 1AZT GSP 0.0000001913 0.57175 3.46154
34 1G6O ADP 0.0006174 0.47279 3.46154
35 2Q2Y ADP 0.0005618 0.44953 3.46154
36 2Q2Y MKR 0.0005373 0.44911 3.46154
37 2I4I AMP 0.00407 0.42588 3.46154
38 1QF5 GDP 0.005326 0.41799 3.46154
39 5I34 GDP 0.00008085 0.40655 3.46154
40 1BG2 ADP 0.0000003776 0.40333 3.46154
41 1EK0 GNP 0.0000003357 0.5461 3.52941
42 3VX3 ADP 0.000489 0.40097 3.62903
43 1D5C GDP 0.00000003298 0.53209 3.7037
44 1NN5 ANP 0.002017 0.41688 3.72093
45 4LC1 GDP 0.00000003305 0.69636 3.84615
46 5JCP GDP ALF 0.0000000341 0.65699 3.84615
47 1SKQ GDP 0.0000000007581 0.52376 3.84615
48 4LYA ATP 0.00008889 0.51895 3.84615
49 4R43 GDP 0.0001257 0.51796 3.84615
50 5FJJ MAN 0.02565 0.42994 3.84615
51 3VM7 GLC 0.02224 0.41881 3.84615
52 3DC4 ADP 0.000003459 0.41836 3.84615
53 2ZR9 DTP 0.00003742 0.40068 3.84615
54 3T5G GDP 0.000000003181 0.54178 3.8674
55 1XTQ GDP 0.00000002307 0.57325 3.9548
56 4LPS GDP 0.00000002988 0.50669 4.13223
57 3TMK T5A 0.001519 0.41883 4.16667
58 3FB4 AP5 0.007931 0.40242 4.16667
59 2OM2 GDP 0.00000007624 0.6252 4.23077
60 5KSZ GCP 0.0000008073 0.60991 4.23077
61 2WKQ GTP 0.0000001052 0.60483 4.23077
62 1FQJ GDP 0.0000001481 0.59859 4.23077
63 1BH2 GSP 0.0000005035 0.55527 4.23077
64 1ZCB GDP 0.0000004339 0.5421 4.23077
65 1Y3A GDP 0.0000001813 0.54106 4.23077
66 1FQK GDP 0.0000003114 0.53312 4.23077
67 3AB3 GDP 0.0000002297 0.52185 4.23077
68 5J1J ANP 0.0003262 0.45823 4.23077
69 2FNA ADP 0.001061 0.4404 4.23077
70 1W0J ADP 0.00004004 0.42551 4.23077
71 5I0H ADP BEF 0.0001797 0.42262 4.23077
72 2CK3 ANP 0.005607 0.416 4.23077
73 5WRI A3P 0.004871 0.41202 4.23077
74 2J5V PCA 0.04941 0.40944 4.23077
75 1FQJ ALF 0.03643 0.40351 4.23077
76 5BQ5 ADP BEF 0.0005554 0.47497 4.2328
77 4KFU ACP 0.000003707 0.40652 4.24528
78 2ODE ALF GDP 0.0000002752 0.56556 4.25532
79 4R2I ANP 0.0003956 0.50581 4.28571
80 3KJI ADP 0.00009345 0.41508 4.33071
81 5FUI APY 0.02125 0.42335 4.54545
82 4J0Q GDP 0.0000000007654 0.7911 4.61538
83 5JBQ GDP 0.000000002187 0.75513 4.61538
84 2BVN GNP 0.000000006188 0.70035 4.61538
85 2C78 GNP 0.00000004613 0.55652 4.61538
86 2C77 GNP 0.00000003054 0.5546 4.61538
87 1D2E GDP 0.00000000971 0.53911 4.61538
88 4G5G GDP 0.000000001859 0.52702 4.61538
89 1D8T GDP 0.000000001968 0.52656 4.61538
90 3U6K GDP 0.000000002438 0.52556 4.61538
91 3U6B GDP 0.0000000009423 0.52529 4.61538
92 4XGU ADP 0.00006707 0.50707 4.61538
93 5CK5 GDP 0.000000009564 0.50243 4.61538
94 5VGR GDP 0.0003093 0.47686 4.61538
95 3E70 GDP 0.000004736 0.44167 4.61538
96 1E2K TMC 0.001334 0.43415 4.61538
97 2QEN ADP 0.00007503 0.42265 4.61538
98 3FWY ADP 0.00008916 0.42119 4.61538
99 5IRN ADP 0.0001366 0.40715 4.61538
100 4GOX A3P 0.001033 0.4049 4.61538
101 1QF9 C5P 0.005579 0.40544 4.63918
102 4TTQ ATP 0.00002755 0.41005 4.65116
103 3H86 AP5 0.002077 0.42036 4.6875
104 2GCO GNP 0.00000001834 0.5415 4.97512
105 2GCN GDP 0.0000003566 0.52234 4.97512
106 4RD0 GDP 0.00000003738 0.55924 5
107 1UPT GTP 0.0000001453 0.5373 5
108 2C04 GCP 0.00004528 0.51484 5
109 5LB3 ADP 0.0003679 0.50088 5
110 4H1V GNP 0.0000004288 0.49912 5
111 4WEI GLC GAL 0.003236 0.46391 5
112 2Y8E GNP 0.0000001541 0.58499 5.02793
113 1NF3 GNP 0.0000001506 0.5854 5.12821
114 5GVR LMR 0.0001781 0.54314 5.12821
115 1OW3 GDP 0.0000002339 0.50383 5.18135
116 1A4R GNH 0.000000004899 0.55884 5.2356
117 1A4R GDP 0.00000001004 0.55856 5.2356
118 4ITR GDP 0.00000005054 0.53033 5.2356
119 2NGR GDP 0.000000004205 0.52369 5.2356
120 1GRN GDP 0.00000005562 0.52141 5.2356
121 5WDR GNP 0.0000001373 0.5678 5.26316
122 2WMO GTP 0.000000001732 0.55242 5.26316
123 5IRC GDP 0.0000003048 0.48276 5.37634
124 4PC3 GDP 0.0000000503 0.65803 5.38462
125 4WZ6 ATP 0.0001882 0.52738 5.38462
126 4XTR ADP 0.0006261 0.45848 5.38462
127 4XTR ATP 0.0007347 0.44341 5.38462
128 4XVU ATP 0.0007709 0.44254 5.38462
129 2WOJ ADP ALF 0.00119 0.42453 5.38462
130 3LXR GDP 0.00000002406 0.68246 5.40541
131 4D0N GDP 0.000000001987 0.52141 5.40541
132 5HPY GDP 0.0000001307 0.51056 5.40541
133 3CX8 GSP 0.0000002586 0.56661 5.41872
134 1RYH GNP 0.000000001487 0.55396 5.41872
135 1KMQ GNP 0.000000275 0.53536 5.43478
136 4YC7 GNP 0.00000003344 0.55828 5.52486
137 2G77 GDP 0.00000001121 0.67897 5.55556
138 2G77 AF3 0.001971 0.47276 5.55556
139 3IIJ ADP 0.00003713 0.40351 5.55556
140 1Z6T ADP 0.001027 0.45314 5.58376
141 4XSH GSP 0.00000003006 0.65097 5.58659
142 4U5X GNP 0.00000002938 0.5441 5.61798
143 1TX4 ALF GDP 0.0000004996 0.57642 5.64972
144 4BQS ADP 0.00002696 0.55128 5.68182
145 1E96 GTP 0.0000001598 0.55797 5.72917
146 1I4D GDP 0.0000000007898 0.52074 5.72917
147 1G7S GDP 0.00000001466 0.70301 5.76923
148 3FKQ ATP 0.0001217 0.4953 5.76923
149 1FP6 ADP 0.00007064 0.41733 5.76923
150 2B8W ALF 5GP 0.0007534 0.41652 5.76923
151 5KSP GDP 0.0000002137 0.6464 5.78947
152 3SBD GNP 0.0000002508 0.57644 5.88235
153 1MH1 GNP 0.0000002714 0.56917 5.91398
154 2W2X GSP 0.00000002733 0.55424 5.94595
155 3MJH GTP 0.00000003174 0.58434 5.95238
156 2EW1 GNP 0.0000001102 0.55036 5.97015
157 1G4U GDP 0.0000002201 0.51248 5.97826
158 1S3G AP5 0.008086 0.40208 5.99078
159 3BER AMP 0.003618 0.44522 6.0241
160 2QG6 NMN 0.002621 0.40804 6.03015
161 3TKL GTP 0.00000007772 0.56274 6.12245
162 1CS4 GSP 0.000001298 0.53698 6.13208
163 1GOJ ADP 0.000001147 0.65734 6.15385
164 4B47 GDP 0.0000000003626 0.53499 6.15385
165 4OHY ANP 0.0002139 0.46184 6.15385
166 4WZA ACP 0.0007783 0.46104 6.15385
167 4WZA ADP 0.0007783 0.46104 6.15385
168 2FJU GSP 0.00000002485 0.55478 6.17978
169 1HE1 GDP 0.0000002595 0.60197 6.25
170 2CJW GDP 0.00000000008011 0.56452 6.25
171 1HE1 AF3 0.01909 0.41736 6.25
172 4CVN ADP 0.000006862 0.40644 6.28272
173 4LHW GNP 0.00000009853 0.59285 6.32184
174 3TNF GNP 0.0000002377 0.56574 6.32184
175 2A9K GDP 0.00000004918 0.52487 6.41711
176 2FFQ GSP 0.0000002362 0.55923 6.43275
177 1ZIN AP5 0.00699 0.40467 6.45161
178 1G16 GDP 0.0000002211 0.52776 6.47059
179 4V0K GDP 0.00000003235 0.57556 6.50888
180 3Q85 GNP 0.000000001243 0.53276 6.50888
181 1Y63 ADP 0.000008805 0.42033 6.52174
182 4BAS GNP 0.00000005475 0.5518 6.53266
183 2NCD ADP 0.000007102 0.60425 6.53846
184 1YRB GDP 0.00000001815 0.53224 6.53846
185 2DPY ADP 0.0001434 0.52891 6.53846
186 5MZN ADP 0.002391 0.46484 6.53846
187 5E5U MLI 0.02104 0.42361 6.53846
188 4KVA GTP 0.0001183 0.40215 6.53846
189 1ZUI SKM 0.0004643 0.44784 6.54762
190 3X1Z GNP 0.0000003726 0.55813 6.58683
191 4HDO GNP 0.0000002974 0.55519 6.58683
192 4HDQ GNP 0.0000004285 0.5492 6.58683
193 1XEX ATP 0.002782 0.41284 6.59341
194 3SFV GDP 0.0000001118 0.53046 6.62983
195 2EFE GNH 0.00000002527 0.52832 6.62983
196 1DS6 GDP 0.000000001284 0.52547 6.66667
197 3E5H GNP 0.0000004502 0.54268 6.74157
198 1GWN GTP 0.00000005637 0.5451 6.82927
199 1GOT GDP 0.0000001608 0.53558 6.84932
200 1ZC3 GNP 0.00000004454 0.5865 6.85714
201 2A5F GTP 0.00000005477 0.56893 6.85714
202 2HT6 GDP 0.0000000005126 0.53109 6.89655
203 1WDT GTP 0.000003408 0.5594 6.92308
204 4DKX GDP 0.0000000003826 0.79286 6.94444
205 1HTW ADP 0.00008738 0.40511 6.96203
206 2F9L GDP 0.0000001206 0.54685 7.03518
207 4M9Q GNP 0.000000073 0.54924 7.04846
208 3RAB GNP 0.00000004394 0.57929 7.10059
209 4KAX GTP 0.0000001539 0.53853 7.10059
210 1U8Z GDP 0.00000004257 0.56375 7.14286
211 3BC1 GNP 0.000000116 0.56372 7.17949
212 1MR3 G3D 0.000000001565 0.54354 7.18232
213 3M1I GTP 0.0000001962 0.56235 7.30594
214 3WYF GTP 0.0000002923 0.56224 7.30594
215 4IDN GNP 0.001107 0.4396 7.30769
216 3IO3 ADP 0.0006109 0.40028 7.30769
217 3N5C GDP 0.000000003734 0.74355 7.40741
218 3NKV GNP 0.00000006974 0.57162 7.42857
219 1G7C 5GP 0.00000005334 0.4891 7.44681
220 3RWO GDP 0.000000309 0.54686 7.56757
221 1M7B GTP 0.00000002818 0.64407 7.6087
222 3CPJ GDP 0.000000009573 0.5389 7.69231
223 5KUT GDP 0.00000001983 0.50981 7.69231
224 1F9V ADP 0.000004762 0.40202 7.69231
225 4KVG GTP 0.0000001199 0.563 7.7381
226 5JCZ GDP 0.00000009154 0.62941 7.82123
227 3Q72 GNP 0.0000000004073 0.53249 7.83133
228 4LX0 BEF GDP 0.0000001543 0.56611 7.9096
229 1MKY GDP 0.00000000002539 0.57602 8.07692
230 1F5N GNP 0.001086 0.42612 8.07692
231 1UAD GNP 0.0000001643 0.55776 8.08081
232 4C4P GNP 0.000000144 0.56705 8.09249
233 2HV8 GTP 0.00000006207 0.57316 8.13953
234 2D7C GTP 0.0000001055 0.56484 8.38323
235 5UWU GNP 0.0000001498 0.57942 8.43882
236 5UWW GNP 0.0000001551 0.57882 8.43882
237 5UWO GNP 0.0000001713 0.5771 8.43882
238 5DHF GNP 0.0000001743 0.5768 8.43882
239 5UWQ GNP 0.0000001827 0.57599 8.43882
240 5UWH GNP 0.0000001829 0.57598 8.43882
241 5UWJ GNP 0.0000001935 0.575 8.43882
242 5UWP GNP 0.0000002233 0.5668 8.43882
243 5UWI GNP 0.0000001679 0.56485 8.43882
244 5UWR GNP 0.0000001908 0.56278 8.43882
245 5DI9 GNP 0.0000003014 0.56172 8.43882
246 5UWS GNP 0.0000003043 0.56156 8.43882
247 3T34 GDP 0.00002395 0.50585 8.46154
248 3ZFD ANP 0.00001678 0.43104 8.46154
249 5H56 TYD 0.001613 0.41929 8.71795
250 5H56 ADP 0.001613 0.41929 8.71795
251 3WYG GTP 0.0000004343 0.55553 8.79121
252 1SVK ALF GDP 0.0000002865 0.56709 8.84615
253 3VMF GTP 0.0000002852 0.54929 8.84615
254 3BFV ADP 0.00009958 0.523 8.84615
255 3DEF GDP 0.000007022 0.45309 8.84615
256 5K5Z ANP 0.003323 0.41273 8.84615
257 4NE2 SH2 0.005856 0.40458 8.84615
258 4NE2 ADP 0.005129 0.40458 8.84615
259 3GJ0 GDP 0.000000004114 0.74146 9.04977
260 3GJ8 GDP 0.000000008093 0.71557 9.04977
261 3GJ4 GDP 0.000000003618 0.5254 9.04977
262 3GJ7 GDP 0.000000004001 0.52362 9.04977
263 3GJ5 GDP 0.000000009006 0.52295 9.04977
264 3GJ3 GDP 0.000000003944 0.52281 9.04977
265 5L3V GDP 0.000003286 0.58092 9.23077
266 5L3S GNP 0.00009561 0.47625 9.23077
267 4ZG4 VO4 ADP 0.0004902 0.4508 9.23077
268 4PJ3 ANP 0.005414 0.42396 9.23077
269 5L3S G 0.01976 0.42064 9.23077
270 2BIF SIN 0.003545 0.41987 9.23077
271 2BIF ANP 0.002502 0.41584 9.23077
272 4HAT GNP 0.000000251 0.56482 9.25926
273 1IBR GNP 0.0000001695 0.56473 9.25926
274 3GJX GTP 0.0000001881 0.56305 9.25926
275 5BXQ GDP 0.000000003109 0.53383 9.25926
276 4XOI GTP 0.0000005862 0.53072 9.25926
277 3CH5 GDP 0.000000008649 0.52297 9.25926
278 2HF9 GSP 0.0000002687 0.61618 9.29204
279 5EE5 GTP 0.0000001598 0.53761 9.38967
280 3ZIA ATP 0.00002728 0.41778 9.42029
281 3ZIA ADP 0.00008935 0.41457 9.42029
282 1X1R GDP 0.0000006323 0.54229 9.55056
283 4P4T GDP 0.0000005436 0.59493 9.61539
284 5XDR ADP 0.0004868 0.48302 9.61539
285 5KDO GDP 0.0000001055 0.61904 10
286 1TAD GDP 0.000000358 0.56108 10
287 1TAD ALF 0.000000358 0.5494 10
288 1JWY GDP 0.0000002793 0.49822 10
289 4YS0 ADP 0.008777 0.41064 10
290 5H67 ATP 0.01518 0.41017 10
291 5ABU GTG 0.03241 0.40923 10
292 2ZTS ADP 0.001548 0.44094 10.3586
293 1IWE IMP 0.006591 0.43893 10.3846
294 4DID GDP 0.00000000262 0.52798 10.5263
295 4DSU GDP 0.0000005073 0.54603 10.582
296 5UQW GDP 0.0000003927 0.53582 10.582
297 1UJ2 ADP 0.002468 0.40477 10.7143
298 1UJ2 C5P 0.003026 0.40153 10.7143
299 1DAR GDP 0.000000002371 0.52684 10.7692
300 3TK1 GDP 0.000000002319 0.50012 10.7692
301 1H65 GDP 0.00002598 0.45847 10.7692
302 1YTM ATP 0.0005733 0.45592 10.7692
303 5TAR GDP 0.00000002073 0.67594 10.8108
304 5TB5 GDP 0.000000009931 0.52687 10.8108
305 3UIE ANP 0.00006231 0.41099 11
306 4PPF FLC 0.0000006868 0.67513 11.1538
307 3WYA GDP 0.00000000006865 0.56573 11.1538
308 1X6V ADP 0.002128 0.41309 11.1538
309 1DAK DPU 0.002332 0.42636 11.1607
310 4YDS ATP 0.0000739 0.544 11.4035
311 1WF3 GNP 0.0000002696 0.55702 11.5385
312 5N69 ADP 0.0009201 0.4598 11.5385
313 5XCO GDP 0.00000001486 0.53106 11.6959
314 5O2T GSP 0.0000002567 0.57013 11.8343
315 5UFQ GNP 0.0000002388 0.57731 12.0482
316 1KY3 GDP 0.0000000295 0.52166 12.0879
317 2C5L GTP 0.0000002592 0.55757 12.1387
318 3QBT GNP 0.0000000865 0.59514 12.1429
319 4K81 GTP 0.00000007995 0.5842 12.2807
320 2XT3 ADP 0.000001082 0.40393 12.3077
321 3PCR GTP 0.0000003731 0.58174 12.3457
322 5E95 GDP 0.00000001047 0.68033 12.5
323 1LFD GNP 0.0000001733 0.55699 12.5749
324 2KIN ADP 0.0000002983 0.40397 12.605
325 2UZI GTP 0.0000001936 0.55557 12.6506
326 1NVU GTP 0.0000002951 0.55518 12.6506
327 1NVV GNP 0.00000035 0.55248 12.6506
328 3DDC GNP 0.0000004011 0.5503 12.6506
329 1WQ1 GDP 0.0000006275 0.52052 12.6506
330 1CLU DBG 0.00000032 0.4681 12.6506
331 1GP2 GDP 0.0000002226 0.59116 12.6761
332 3B9Q MLI 0.00005427 0.55969 12.6923
333 5M04 GDP 0.000000004226 0.51354 12.6923
334 5L3R GCP 0.00003962 0.49201 12.6923
335 1RJ9 GCP 0.0005906 0.45207 12.8289
336 2QN6 GDP 0.0000000001961 0.53835 12.9032
337 2OFW ADX 0.002846 0.41957 12.9808
338 4P3Y GDP 0.0000000009579 0.52437 13.1868
339 2XTZ GSP 0.0000004449 0.54236 13.4615
340 1KK1 GNP 0.000000003946 0.51291 13.4615
341 1GUA GNP 0.0000002717 0.56915 13.5802
342 1LVG ADP 0.000008167 0.40561 13.6364
343 5FTB ANP 0.00115 0.45994 13.8462
344 5FHD ADP ALF 0.002567 0.42747 13.8462
345 3A4M ADP 0.000009977 0.40419 13.8462
346 1TU3 GNP 0.00000004456 0.57889 13.9241
347 2FH5 GTP 0.000000008061 0.5724 14.0187
348 2PEZ DAT 0.002077 0.41775 14.5251
349 4HI0 GDP 0.0000001845 0.60844 14.5669
350 3CNL GNP 0.0000000005994 0.52941 14.6154
351 3KUD GDP 0.0000001137 0.52986 14.8148
352 3REF GDP 0.00000003916 0.55647 14.9485
353 1KAO GDP 0.0000001221 0.51332 14.9701
354 5HCN GCP 0.00000001381 0.70427 15
355 2V7Q ATP 0.00002242 0.4253 15.1515
356 2W83 GTP 0.0000002029 0.54133 15.5844
357 5DIF GNP 0.0000001289 0.58201 15.7895
358 3WXM GTP 0.0000003537 0.54589 16.1538
359 3ZQ6 ADP ALF 0.0005161 0.43122 16.5385
360 1CXZ GSP 0.000000103 0.54307 17.4419
361 1PUJ GNP 0.0000000008576 0.57831 18.0769
362 2XTN GTP 0.000007354 0.48439 18.3761
363 3WY9 GDP 0.0000000002544 0.53699 18.75
364 3T12 GDP ALF 0.0000001426 0.60615 19.697
365 3T1O GDP 0.00000002151 0.52306 19.697
366 4D0G GTP 0.00000003197 0.55953 20.2899
367 3ZS9 ADP ALF 0.001578 0.41256 21.0526
368 4WOP CTP 0.001621 0.43619 21.3333
369 3DOE GTP 0.00000007918 0.55582 21.875
370 3AQ4 GDP 0.000000001051 0.54972 22.2826
371 1KSH GDP 0.00000001486 0.56359 22.5806
372 2VOH CIT 0.02958 0.41586 23.0769
373 2GJ8 ALF GDP 0.0000007445 0.55176 23.2558
374 2X77 GDP 0.0000000003296 0.56219 23.8095
375 4YLG GDP 0.000000002799 0.70641 24.2775
376 2QTV GNP 0.0000002541 0.54524 24.5509
377 5SZH GNP 0.0000001348 0.56816 24.8366
378 2J59 GTP 0.0000001645 0.54441 25.3012
379 4DCT GDP 0.000000001432 0.54248 25.3846
380 4ZI2 GNP 0.00000006035 0.62214 27.3684
381 4GOJ GNP 0.0000000585 0.55298 27.5132
382 2BME GNP 0.00000003306 0.58366 27.957
383 1SVI GDP 0.000000000446 0.5329 28.2051
384 1TQ4 GDP 0.00000003156 0.64193 28.4615
385 1FZQ GDP 0.000000001099 0.53749 28.7293
386 4TMZ GSP 0.00000008304 0.55549 28.8462
387 4NCN GTP 0.00000009747 0.55282 28.8462
388 1W7J ADP BEF 0.001088 0.45199 29.2308
389 3P13 RIP 0.03255 0.4192 30.5556
390 2ZEJ GDP 0.00000356 0.51413 32.0652
391 2HCJ GDP 0.0000000005578 0.52924 32.4324
392 5DI3 GNP 0.0000001079 0.61133 33.5135
393 5FG3 GDP 0.0000000004717 0.53174 34.6154
394 3PQC GDP 0.00000004941 0.50935 36.4103
395 5UWT GNP 0.0000002113 0.5611 39.1304
Pocket No.: 2; Query (leader) PDB : 4NON; Ligand: GDP; Similar sites found: 186
This union binding pocket(no: 2) in the query (biounit: 4non.bio2) has 16 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 3B7G ANP 0.000232 0.48044 None
2 2IL4 COA 0.005147 0.42173 None
3 1Q20 PLO 0.01068 0.42812 2.30769
4 1T8U UAP SGN IDS SGN 0.01452 0.42771 2.30769
5 1T8U A3P 0.006121 0.42406 2.30769
6 1J99 AND 0.01316 0.4235 2.30769
7 3SXN COA 0.007888 0.42048 2.30769
8 3MGB PAP 0.009138 0.4156 2.30769
9 1XVV CCQ 0.04002 0.40554 2.30769
10 3DKP ADP 0.0005865 0.45871 2.44898
11 1ION ADP 0.00006273 0.51008 2.46914
12 3IUY AMP 0.001744 0.43665 2.63158
13 5TSH ANP 0.00002102 0.5261 2.69231
14 5TSH ADP 0.000003624 0.51828 2.69231
15 1XKV ATP 0.00005459 0.51293 2.69231
16 1CR1 TTP 0.0001769 0.49867 2.69231
17 3FYH ADP 0.0003944 0.48786 2.69231
18 2OZE AGS 0.0005656 0.47207 2.69231
19 2GDJ ANP 0.0004552 0.46385 2.69231
20 4JLV ADP 0.0009642 0.44286 2.69231
21 4KBF AMP 0.001193 0.43761 2.69231
22 4JD3 PLM 0.02292 0.42183 2.69231
23 4JD3 COA 0.02126 0.42183 2.69231
24 4D42 NAP 0.04453 0.41098 2.69231
25 4D42 W0I 0.04453 0.41098 2.69231
26 3OZ2 FAD 0.04791 0.40226 2.69231
27 4E03 ADP 0.0001025 0.4971 2.91262
28 5IFS ADP 0.00008831 0.50306 3.07692
29 1OS1 ATP 0.0003706 0.49623 3.07692
30 1OS1 PYR 0.000399 0.49623 3.07692
31 1R6B ADP 0.0001768 0.48598 3.07692
32 1NY5 ADP 0.0005984 0.46863 3.07692
33 1G3M PCQ 0.01062 0.43377 3.07692
34 2ZPT A3P 0.01876 0.43272 3.07692
35 5K6A NAP 0.01404 0.41966 3.07692
36 2GWH A3P 0.006407 0.41925 3.07692
37 3JQ8 NAP 0.02928 0.4034 3.07692
38 4CM9 NAP 0.02993 0.40291 3.07692
39 5EP2 AZU 0.006289 0.42349 3.125
40 1NJF ADP 0.00008534 0.51164 3.2
41 2QQ0 TMP 0.0001305 0.52385 3.26087
42 2QQ0 ANP 0.0001409 0.52215 3.26087
43 2QQ0 THM 0.0001216 0.52215 3.26087
44 3P4X ADP 0.00005968 0.49618 3.38983
45 2PL3 ADP 0.0003531 0.46113 3.38983
46 1RRC ADP 0.000001876 0.512 3.46154
47 2IS6 ADP 0.0001412 0.48754 3.46154
48 1XP8 AGS 0.00012 0.48097 3.46154
49 1QF5 RPL 0.03586 0.43955 3.46154
50 2OBM ADP 0.0002273 0.43523 3.46154
51 3BD9 A3P 0.006212 0.41334 3.46154
52 1U1I NAD 0.02994 0.40733 3.46154
53 5ITV NAI 0.03575 0.4001 3.52941
54 3QXC ATP 0.0005758 0.48334 3.71901
55 2C9O ADP 0.00004348 0.5282 3.84615
56 2QZ4 ADP 0.00007864 0.50544 3.84615
57 1QHG ATP 0.008177 0.41213 3.84615
58 1S7N COA 0.01095 0.41177 3.84615
59 1OYY AGS 0.006653 0.40949 3.84615
60 4PSW COA 0.01046 0.40701 3.84615
61 2YNC YNC 0.04066 0.40141 3.84615
62 2BEK ATP 0.002912 0.46171 3.89105
63 2JAQ DCP 0.004434 0.43445 3.90244
64 1OE0 TTP 0.005412 0.435 3.91304
65 1UKZ ADP 0.0003821 0.50168 3.94089
66 2B8T THM 0.003107 0.44023 4.03587
67 4LJ9 ACP 0.0006709 0.45599 4.12979
68 2VVG ADP 0.0000007716 0.51159 4.23077
69 4BFW ZVW 0.0003692 0.51037 4.23077
70 5WRJ A3P 0.0005763 0.47975 4.23077
71 3Q9L ATP 0.0005605 0.46999 4.23077
72 3FVQ ATP 0.0009343 0.46366 4.23077
73 1W0J ADP BEF 0.0009287 0.46169 4.23077
74 3EZ2 ADP 0.0006175 0.45024 4.23077
75 1AQU A3P 0.004328 0.42744 4.23077
76 4OI4 ATP 0.0003123 0.49089 4.34783
77 1KUV CA5 0.02268 0.41024 4.34783
78 2CE7 ADP 0.00003759 0.5206 4.61538
79 2ZPA ADP 0.000139 0.50143 4.61538
80 2AWN ADP 0.000001216 0.48274 4.61538
81 4A4Z ANP 0.002785 0.42716 4.61538
82 1VKJ A3P 0.006556 0.42261 4.61538
83 2GK6 ADP 0.001919 0.42188 4.61538
84 3E1T FAD 0.0268 0.41822 4.61538
85 4V03 ADP 0.00005666 0.51217 4.66926
86 4TMK T5A 0.01285 0.42403 4.69484
87 4ITM ATP 0.01131 0.41759 4.7619
88 2RGX AP5 0.0006912 0.49857 4.85437
89 1T5C ADP 0.0000005098 0.51745 5
90 1P9B GDP 0.0000652 0.51474 5
91 3NHB ADP 0.00003049 0.48272 5
92 4FCW ADP 0.0007234 0.45724 5
93 1KO8 6PG 0.00008979 0.51057 5.14286
94 4P32 ADP 0.0004031 0.48345 5.22088
95 2CHG ANP 0.0001254 0.50114 5.30973
96 1JJV ATP 0.00004758 0.47921 5.33981
97 5HGZ ACO 0.02447 0.40088 5.34979
98 1XMV ADP 0.00005494 0.50982 5.38462
99 1IN4 ADP 0.0000933 0.50977 5.38462
100 4GBM A3P 0.0001543 0.50588 5.38462
101 3LRE ADP 0.000001786 0.4984 5.38462
102 3DZD ADP 0.0001754 0.49162 5.38462
103 1YQT ADP 0.00001893 0.49093 5.38462
104 2IXE ATP 0.0003695 0.48529 5.38462
105 1R0X ATP 0.0004898 0.45459 5.38462
106 2FSH ANP 0.00158 0.43121 5.38462
107 2O4C NAD 0.0292 0.40462 5.38462
108 1CJW COT 0.01208 0.42039 5.42169
109 5MVR ADP 0.00005894 0.50523 5.55556
110 1K6M AGS 0.00002943 0.54109 5.76923
111 1U0J ADP 0.0001306 0.4789 5.76923
112 2Z5F A3P 0.002776 0.44073 5.76923
113 4IOK XPO 0.006394 0.42829 5.76923
114 4IOK ADP 0.007892 0.42829 5.76923
115 2W58 ADP 0.00000669 0.47679 5.94059
116 3ORF NAD 0.02005 0.41057 5.9761
117 2PZE ATP 0.00001376 0.48139 6.11354
118 5M7P ADP 0.0002697 0.48757 6.15385
119 2VF7 ADP 0.0003004 0.47517 6.15385
120 1NST A3P 0.0007917 0.4628 6.15385
121 4HUT ATP 0.01364 0.41904 6.28272
122 4MKF AP5 0.0005831 0.50127 6.45161
123 4MKG AP5 0.000964 0.4888 6.45161
124 5HR5 ADP 0.00002442 0.53517 6.53846
125 4HSE ADP 0.00004212 0.51524 6.53846
126 2XAU ADP 0.0002035 0.48591 6.53846
127 2JLR ANP 0.0006584 0.46428 6.53846
128 3BFX A3P 0.002728 0.43913 6.53846
129 5HR5 FLC 0.01305 0.42249 6.53846
130 3KTA AP5 0.0001954 0.4894 6.59341
131 4QRH 0O2 0.0134 0.40749 6.66667
132 3EWA ANP 0.000182 0.48241 6.8323
133 2JDC CAO 0.02555 0.40397 6.84932
134 5LTJ ADP 0.0001745 0.48625 6.92308
135 4KVX ACO 0.01073 0.4202 7.05128
136 2ZE7 AMP 0.001332 0.46359 7.11462
137 2ZE7 DST 0.001439 0.46359 7.11462
138 3RC3 ANP 0.0007156 0.4465 7.30769
139 4E5N NAD 0.01204 0.42429 7.30769
140 1P31 EPU 0.01288 0.40655 7.30769
141 2D1S SLU 0.03119 0.40199 7.30769
142 5G41 AP5 0.001034 0.49264 7.62332
143 2FAH GDP 0.0001712 0.49213 7.69231
144 4PFO ADP 0.0002101 0.50322 8.07692
145 3RLF ANP 0.0007654 0.47183 8.07692
146 5MEX SZZ 0.02012 0.41835 8.07692
147 5MEX PAP 0.007915 0.41678 8.07692
148 1VHT BA3 0.0004731 0.46858 8.25688
149 1W5T ANP 0.001602 0.45231 8.46154
150 1W5T ADP 0.002565 0.43834 8.46154
151 2O0J ADP 0.001055 0.43246 8.46154
152 4M1U MBG A2G 0.01655 0.40788 8.57143
153 2VB6 ADP BEF 0.0001657 0.50436 8.72483
154 1SQ5 ADP 0.00003525 0.51887 8.84615
155 2WHX ADP 0.0001143 0.46004 8.84615
156 4IHQ ADP 0.00001797 0.51763 9.23077
157 1G41 ADP 0.0001651 0.4902 9.23077
158 1XX6 ADP 0.0005954 0.45841 9.42408
159 3BOS CDP 0.00009483 0.4956 9.61539
160 2VBQ BSJ 0.01358 0.42505 9.69697
161 1JWY ADP 0.0001499 0.48935 10
162 1F2U ATP 0.0005166 0.48568 10.0671
163 3R96 ACO 0.03314 0.40704 10.1064
164 3R96 AMP 0.03314 0.40704 10.1064
165 1B7T ADP 0.0001767 0.48881 10.2564
166 4I9B 1KA 0.02268 0.41802 10.3846
167 1KK8 BEF ADP 0.0001398 0.49888 10.3896
168 4FRZ ADP 0.000003239 0.52356 10.7692
169 3H4V DVP 0.04719 0.40429 10.7692
170 2F3R G5P 0.008125 0.43297 11.1111
171 1OFH ADP 0.000398 0.47214 11.4943
172 2OG2 MLI 0.00001532 0.41381 11.5385
173 3QF7 ANP 0.0003181 0.48411 12
174 2ORV 4TA 0.002711 0.44833 12.3932
175 2D2F ADP 0.0003257 0.4069 12.4
176 2D7D ADP 0.000518 0.46123 12.5
177 3H4S ADP 0.00000133 0.52131 12.5926
178 3V2U ATP 0.006057 0.42608 12.6923
179 1SVM ATP 0.0006385 0.50567 13.0769
180 1X9I G6Q 0.006066 0.40418 15
181 2V7Q ADP 0.0008516 0.45116 15.1515
182 1W4R TTP 0.0002553 0.50263 15.8974
183 3QKT ANP 0.0002746 0.49559 16.1538
184 4QM7 GTP 0.00004726 0.5097 17.5439
185 1BO4 COA 0.001588 0.43854 22.0238
186 3TBK ANP 0.001312 0.42877 24.6154
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