Receptor
PDB id Resolution Class Description Source Keywords
3CBP 1.42 Å EC: 2.1.1.43 SET7/9-ER-SINEFUNGIN COMPLEX HOMO SAPIENS ESTROGEN RECEPTOR PROTEIN LYSINE METHYLATION ACTIVATOR CHREGULATOR CHROMOSOMAL PROTEIN METHYLTRANSFERASE NUCLEUSADENOSYL-L-METHIONINE TRANSCRIPTION TRANSCRIPTION REGULATTRANSFERASE DNA-BINDING LIPID-BINDING METAL-BINDING PHOSPHOPROTEIN STEROID-BINDING ZINC-FINGER TRANSFERASE- TRANSFERASE RECEPTOR COMPLEX
Ref.: REGULATION OF ESTROGEN RECEPTOR ALPHA BY THE SET7 L METHYLTRANSFERASE. MOL.CELL V. 30 336 2008
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
BME A:395;
A:396;
A:397;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
78.133 C2 H6 O S C(CS)...
GOL A:1502;
Invalid;
none;
submit data
92.094 C3 H8 O3 C(C(C...
ILE LYS ARG SER LYS LYS ASN SER LEU ALA B:299;
Valid;
none;
submit data
447.561 n/a O=C(N...
SFG A:1501;
Valid;
none;
submit data
381.387 C15 H23 N7 O5 c1nc(...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
5AYF 2.01 Å EC: 2.1.1.43 CRYSTAL STRUCTURE OF SET7/9 IN COMPLEX WITH CYPROHEPTADINE HOMO SAPIENS SET DOMAIN METHYLTRANSFERASE INHIBITOR TRANSFERASE-TRANSFINHIBITOR COMPLEX
Ref.: IDENTIFICATION OF CYPROHEPTADINE AS AN INHIBITOR OF DOMAIN CONTAINING LYSINE METHYLTRANSFERASE 7/9 (SET REGULATES ESTROGEN-DEPENDENT TRANSCRIPTION J.MED.CHEM. V. 59 3650 2016
Members (11)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 36 families.
1 3VUZ - K15 C20 H33 N7 O5 CCCCCCN(CC....
2 3VV0 - KH3 C22 H38 N8 O5 CCCCCCNCCN....
3 3CBO - ILE LYS ARG SER MLZ LYS ASN SER LEU ALA n/a n/a
4 3CBP - ILE LYS ARG SER LYS LYS ASN SER LEU ALA n/a n/a
5 5EG2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
6 3OS5 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
7 1XQH - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 1N6A - SAM C15 H22 N6 O5 S C[S@@+](CC....
9 1O9S - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 5AYF ic50 = 1 uM C7H C21 H21 N CN1CCC(=C2....
11 3CBM - ILE LYS ARG SER MLZ LYS ASN SER LEU ALA n/a n/a
70% Homology Family (13)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 26 families.
1 1MT6 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1N6C - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 3VUZ - K15 C20 H33 N7 O5 CCCCCCN(CC....
4 3VV0 - KH3 C22 H38 N8 O5 CCCCCCNCCN....
5 3CBO - ILE LYS ARG SER MLZ LYS ASN SER LEU ALA n/a n/a
6 3CBP - ILE LYS ARG SER LYS LYS ASN SER LEU ALA n/a n/a
7 5EG2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 3OS5 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
9 1XQH - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 1N6A - SAM C15 H22 N6 O5 S C[S@@+](CC....
11 1O9S - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 5AYF ic50 = 1 uM C7H C21 H21 N CN1CCC(=C2....
13 3CBM - ILE LYS ARG SER MLZ LYS ASN SER LEU ALA n/a n/a
50% Homology Family (13)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 22 families.
1 1MT6 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
2 1N6C - SAM C15 H22 N6 O5 S C[S@@+](CC....
3 3VUZ - K15 C20 H33 N7 O5 CCCCCCN(CC....
4 3VV0 - KH3 C22 H38 N8 O5 CCCCCCNCCN....
5 3CBO - ILE LYS ARG SER MLZ LYS ASN SER LEU ALA n/a n/a
6 3CBP - ILE LYS ARG SER LYS LYS ASN SER LEU ALA n/a n/a
7 5EG2 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
8 3OS5 - SAH C14 H20 N6 O5 S c1nc(c2c(n....
9 1XQH - SAH C14 H20 N6 O5 S c1nc(c2c(n....
10 1N6A - SAM C15 H22 N6 O5 S C[S@@+](CC....
11 1O9S - SAH C14 H20 N6 O5 S c1nc(c2c(n....
12 5AYF ic50 = 1 uM C7H C21 H21 N CN1CCC(=C2....
13 3CBM - ILE LYS ARG SER MLZ LYS ASN SER LEU ALA n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: ILE LYS ARG SER LYS LYS ASN SER LEU ALA; Similar ligands found: 83
No: Ligand ECFP6 Tc MDL keys Tc
1 ILE LYS ARG SER LYS LYS ASN SER LEU ALA 1 1
2 LYS ALA ALA ARG ALY SER ALA PRO ALA 0.632911 0.94
3 ALA ARG M3L SER 0.620253 0.75
4 ILE LYS ARG SER MLZ LYS ASN SER LEU ALA 0.617284 0.886792
5 LYS ARG LYS ARG LYS ARG LYS ARG 0.613333 0.833333
6 ACE ALA ARG THR LYS GLN 0.55814 0.938776
7 ALA ILE ARG SER 0.555556 0.86
8 ARG ARG ARG ARG ARG ARG ARG ARG 0.554054 0.8125
9 ALA ARG THR LYS GLN THR ALA ARG 0.547368 0.901961
10 ALA ARG THR LYS GLN THR ALA ARG LYS 0.547368 0.901961
11 ALA MET ARG VAL 0.530864 0.722222
12 ALA ARG THR MLY GLN THR ALA ARG LYS SER 0.528736 0.862745
13 DMG PRO ARG ARG ARG SER ARG LYS PRO 0.525773 0.712121
14 ALA ARG ALA ALA ALA ALA ALA ALA ALA 0.513158 0.816327
15 ALA TYR ARG 0.511905 0.759259
16 ALA ARG M3L SER CYS GLY GLY LYS 08P 0.508772 0.691176
17 ALA ARG THR MLY GLN THR ALA ARG MLY SER 0.505376 0.779661
18 ALA ARG LYS SEP THR GLY GLY LYS 0.490566 0.79661
19 LYS ALA ALA ARG M3L SER ALA 0.489796 0.783333
20 ARG GLU ARG SER PRO THR ARG 0.489362 0.754098
21 PRO ALA ALA LYS ARG VAL LYS LEU ASP 0.488095 0.836735
22 LYS ARG ARG LYS SEP VAL 0.483146 0.775862
23 ALA ARG THR M3L GLN THR ALA DA2 LYS 0.483051 0.741935
24 LYS ARG LYS 0.480519 0.854167
25 ALA ARG 0.478261 0.791667
26 ALA ARG THR MLY GLN THR ALA ARG LYS 0.475728 0.766667
27 ALA ARG THR LYS GLN THR ALA ARG LYS SER 0.474747 0.901961
28 ALA ARG TPO LYS 0.47191 0.758621
29 LYS ARG LYS ARG LYS ARG LYS ARG LYS ARG 0.468354 0.836735
30 ALA ARG THR 4WQ GLN THR ALA ARG LYS SER 0.467391 0.836364
31 ALA ARG LYS ILE ASP ASN LEU ASP 0.466667 0.785714
32 GLU ALY ARG 0.465116 0.823529
33 THR ALA ARG M3L SER THR 0.465116 0.75
34 VAL ALA ARG SER 0.463415 0.86
35 ALA PRO ALA LEU ARG VAL VAL LYS 0.461538 0.823529
36 SER SER ARG LYS GLU TYR TYR ALA 0.45 0.728814
37 ALA LYS ALA SER GLN ALA ALA 0.449438 0.816327
38 ALA THR ARG ASN PHE SER GLY 0.444444 0.803571
39 ALA ARG THR ALY GLN THR ALA 0.444444 0.867925
40 ALA LYS ARG HIS ARG LYS VAL LEU ARG ASP 0.442478 0.693548
41 LYS GLN THR ALA ARG M3L SER THR GLY 0.442308 0.758065
42 GLY ALA ARG 0.441558 0.77551
43 ALA ARG THR MLY GLN THR ALA 0.44 0.766667
44 ALA ARG THR M3L GLN THR ALA 2MR LYS 0.44 0.741935
45 ALA ARG THR M3L GLN THR ALA 0.44 0.741935
46 ALA ARG THR MLY GLN THR ALA ARG LYS TYR 0.44 0.766667
47 ALA ARG THR M3L GLN THR ALA ARG LYS SER 0.44 0.741935
48 ACE ARG LYS VAL ARG MET 5XU 0.436782 0.722222
49 GLU ARG GLY SER GLY ARG 0.43617 0.882353
50 ARG SER ARG 0.435897 0.897959
51 ALA ARG THR MLZ GLN THR ALA ARG LYS TYR 0.435644 0.836364
52 ALA ARG THR M3L GLN THR ALA ARG LYS 0.435644 0.741935
53 ALA THR PRK ALA ALA ARG LYS SER 0.431579 0.735849
54 VAL ARG SER ARG ARG CYS LEU ARG LEU 0.431579 0.867925
55 VAL ALA PHE ARG SER 0.43 0.826923
56 ALA GLN PHE SER ALA SER ALA SER ARG 0.427184 0.833333
57 GLN LEU ALA THR M3L ALA ALA ARG LYS SER 0.426087 0.741935
58 ALA ARG MLZ SER ALA PRO ALA THR 0.424779 0.712121
59 ALA ARG THR MLY GLN 0.42268 0.766667
60 VAL ARG SER ARG ARG ABA LEU ARG LEU 0.42268 0.867925
61 LEU GLY GLY ALA LYS GLN ARG GLY ASP VAL 0.421569 0.826923
62 SER ARG LYS ILE ASP ASN LEU ASP 0.419643 0.839286
63 ALA ARG MLZ SER THR GLY GLY ALY 0.415929 0.810345
64 ARG ALA ARG 0.4125 0.791667
65 ALA ALA LEU THR ARG ALA 0.412371 0.862745
66 ALA ARG MLY SER THR GLY GLY ALY 0.412281 0.758065
67 ALA ARG M3L SER THR GLY GLY ALY 0.412281 0.734375
68 ARG ARG ARG ARG ARG ARG ARG ARG ARG ARG 0.410256 0.816327
69 ALA LYS ALA ALA 0.410256 0.666667
70 ARG ARG ALA ALA 0.409639 0.8
71 THR ALA ARG MYK SER THR GLY 0.408696 0.839286
72 GLY ARG GLY ASP SER PRO 0.408602 0.86
73 GLN THR ALA ARG M3L SER THR GLY 0.40708 0.758065
74 ARG ARG ARG ARG SER TRP TYR 0.40708 0.714286
75 MET ARG THR GLY ASN ALA XSN 0.40625 0.732143
76 ALA ARG THR M3L GLN THR ALA ALA LYS ALA 0.405405 0.730159
77 GLU THR VAL ARG PHE GLN SER ASP 0.404959 0.803571
78 ASN ARG LEU ILE LEU THR GLY 0.40404 0.754717
79 GLY THR LEU SER ASN ARG ALA SER LYS LEU 0.402299 0.764706
80 ASN LEU LEU GLN LYS LYS 0.402174 0.673077
81 THR PRO ARG ARG SER MLZ SER ALA 0.401786 0.701493
82 HIS HIS ALA SER PRO ARG LYS 0.401575 0.71875
83 ALA ARG THR MLZ GLN THR ALA ARG LYS 0.4 0.807018
Ligand no: 2; Ligand: SFG; Similar ligands found: 218
No: Ligand ECFP6 Tc MDL keys Tc
1 SFG 1 1
2 0UM 0.689655 0.887324
3 SAI 0.654762 0.940298
4 SA8 0.642857 0.9
5 SAH 0.635294 0.954545
6 EEM 0.62069 0.875
7 5X8 0.619048 0.924242
8 S7M 0.606742 0.875
9 RAB 0.597222 0.850746
10 XYA 0.597222 0.850746
11 ADN 0.597222 0.850746
12 5CD 0.594595 0.863636
13 5N5 0.581081 0.850746
14 62X 0.574468 0.84
15 A4D 0.573333 0.850746
16 K15 0.568421 0.863014
17 DTA 0.564103 0.84058
18 6RE 0.560976 0.833333
19 SAM 0.555556 0.875
20 EP4 0.551282 0.802817
21 KB1 0.55102 0.887324
22 M2T 0.544304 0.780822
23 SMM 0.537634 0.84
24 MTA 0.5375 0.826087
25 ZAS 0.53012 0.816901
26 A 0.53012 0.77027
27 AMP 0.53012 0.77027
28 J7C 0.529412 0.84507
29 3DH 0.52439 0.826087
30 GJV 0.523256 0.821918
31 SON 0.522727 0.813333
32 0XU 0.522222 0.938462
33 SRP 0.521277 0.813333
34 SSA 0.521277 0.697674
35 AMP MG 0.517647 0.75
36 AOC 0.517647 0.826087
37 CA0 0.516854 0.776316
38 5AL 0.516129 0.786667
39 AMO 0.515464 0.813333
40 DSZ 0.515464 0.717647
41 GSU 0.515152 0.738095
42 KH3 0.514286 0.851351
43 A2D 0.511628 0.75
44 A3N 0.511628 0.814286
45 ABM 0.511628 0.75
46 A5A 0.510638 0.682353
47 5CA 0.510417 0.697674
48 SRA 0.505882 0.730769
49 S4M 0.505747 0.792208
50 AN2 0.505618 0.74026
51 A7D 0.505618 0.882353
52 A3S 0.505618 0.895522
53 GAP 0.505376 0.776316
54 LSS 0.5 0.681818
55 VMS 0.5 0.666667
56 DSH 0.5 0.871429
57 AP2 0.5 0.766234
58 LAD 0.5 0.818182
59 ADX 0.5 0.678571
60 BA3 0.5 0.75
61 M33 0.5 0.74026
62 A12 0.5 0.766234
63 KAA 0.5 0.712644
64 54H 0.5 0.666667
65 Y3J 0.5 0.80303
66 SXZ 0.49505 0.875
67 ME8 0.49505 0.775
68 AHX 0.494949 0.759494
69 TSB 0.494845 0.674419
70 53H 0.494845 0.659091
71 G5A 0.494624 0.697674
72 50T 0.494505 0.74026
73 AP5 0.494382 0.75
74 5AS 0.494382 0.640449
75 ADP 0.494382 0.75
76 B4P 0.494382 0.75
77 8QN 0.489796 0.786667
78 GEK 0.489796 0.913043
79 5AD 0.486842 0.828125
80 PAJ 0.484848 0.728395
81 52H 0.484536 0.659091
82 AU1 0.483516 0.730769
83 ADP MG 0.483516 0.74026
84 MAO 0.483146 0.782051
85 NEC 0.482759 0.797101
86 A3G 0.482759 0.882353
87 3AM 0.482353 0.733333
88 YAP 0.480769 0.802632
89 7D7 0.480519 0.794118
90 TXA 0.480392 0.766234
91 NB8 0.480392 0.782051
92 NVA LMS 0.48 0.681818
93 DAL AMP 0.479592 0.786667
94 ATF 0.479167 0.721519
95 ATP 0.478261 0.75
96 BEF ADP 0.478261 0.721519
97 ACP 0.478261 0.753247
98 ADP BEF 0.478261 0.721519
99 A3T 0.478261 0.852941
100 7MD 0.476636 0.775
101 XAH 0.47619 0.775
102 YSA 0.47619 0.697674
103 PRX 0.473118 0.753247
104 APR 0.473118 0.773333
105 AR6 0.473118 0.773333
106 AQP 0.473118 0.75
107 APC 0.473118 0.766234
108 5FA 0.473118 0.75
109 WAQ 0.470588 0.815789
110 4AD 0.47 0.802632
111 NSS 0.47 0.697674
112 AD9 0.468085 0.730769
113 RBY 0.468085 0.789474
114 AGS 0.468085 0.7125
115 SAP 0.468085 0.7125
116 ADV 0.468085 0.789474
117 ADP PO3 0.468085 0.77027
118 A5D 0.468085 0.84058
119 MHZ 0.467391 0.782051
120 FA5 0.466667 0.813333
121 PTJ 0.466019 0.7375
122 00A 0.465347 0.746835
123 D3Y 0.464646 0.869565
124 ATP MG 0.463158 0.74026
125 VRT 0.463158 0.871429
126 LEU LMS 0.460784 0.662921
127 OOB 0.46 0.786667
128 S8M 0.46 0.859155
129 ADP VO4 0.459184 0.74026
130 VO4 ADP 0.459184 0.74026
131 ACQ 0.458333 0.753247
132 TAT 0.458333 0.721519
133 ANP 0.458333 0.730769
134 AAT 0.453608 0.847222
135 2AM 0.453488 0.723684
136 FYA 0.451923 0.786667
137 YLC 0.451327 0.797468
138 DLL 0.45098 0.786667
139 A3P 0.450549 0.746667
140 YLP 0.45045 0.777778
141 A22 0.45 0.74026
142 ADP ALF 0.44898 0.7125
143 ALF ADP 0.44898 0.7125
144 TYR AMP 0.448598 0.789474
145 2VA 0.446809 0.828571
146 3UK 0.446602 0.776316
147 OAD 0.446602 0.776316
148 ANP MG 0.444444 0.7125
149 IOT 0.443478 0.768293
150 9SN 0.443396 0.7375
151 P5A 0.442308 0.704545
152 PR8 0.442308 0.807692
153 7D5 0.44186 0.714286
154 A1R 0.441176 0.769231
155 7C5 0.440367 0.797297
156 TT8 0.44 0.926471
157 YLA 0.439655 0.777778
158 YLB 0.438596 0.777778
159 1ZZ 0.438095 0.753086
160 3OD 0.438095 0.776316
161 BIS 0.438095 0.725
162 NVA 2AD 0.4375 0.816901
163 MAP 0.435644 0.7125
164 MYR AMP 0.433962 0.753086
165 NAI 0.433628 0.725
166 SO8 0.43299 0.816901
167 A6D 0.432692 0.74359
168 5SV 0.431373 0.7375
169 25A 0.431373 0.75
170 TYM 0.429825 0.813333
171 WSA 0.429825 0.705882
172 3NZ 0.428571 0.833333
173 ARG AMP 0.428571 0.765432
174 LAQ 0.428571 0.753086
175 ADQ 0.427184 0.753247
176 7MC 0.426087 0.756098
177 48N 0.424779 0.759494
178 LPA AMP 0.424779 0.753086
179 JB6 0.424528 0.746835
180 PPS 0.424242 0.658824
181 AYB 0.423729 0.768293
182 PAP 0.42268 0.736842
183 OVE 0.422222 0.696203
184 3AD 0.421687 0.863636
185 4YB 0.419643 0.72093
186 CMP 0.419355 0.753425
187 2BA 0.419355 0.743243
188 A2P 0.419355 0.733333
189 ADP BMA 0.419048 0.753247
190 4UV 0.418182 0.75641
191 ALF ADP 3PG 0.417391 0.75
192 LA8 ALF 3PG 0.417391 0.75
193 AHZ 0.415929 0.731707
194 QQX 0.41573 0.670886
195 A A 0.415094 0.75
196 AP0 0.413793 0.695122
197 ATP A A A 0.412844 0.76
198 RP1 0.411111 0.705128
199 QQY 0.411111 0.679487
200 SP1 0.411111 0.705128
201 ACK 0.411111 0.716216
202 AFH 0.410714 0.728395
203 4UU 0.410714 0.75641
204 DND 0.408696 0.766234
205 TXD 0.408696 0.725
206 NXX 0.408696 0.766234
207 7D3 0.408602 0.696203
208 25L 0.407407 0.74026
209 CC5 0.407407 0.876923
210 TAD 0.40708 0.75
211 AMP DBH 0.405405 0.753247
212 TXE 0.405172 0.725
213 OMR 0.405172 0.743902
214 AF3 ADP 3PG 0.405172 0.75
215 MTP 0.404762 0.72973
216 N0B 0.401575 0.777778
217 V3L 0.4 0.773333
218 YLY 0.4 0.768293
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 5AYF; Ligand: SAM; Similar sites found: 20
This union binding pocket(no: 1) in the query (biounit: 5ayf.bio1) has 39 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2BVE PH5 0.007458 0.41372 None
2 5LFV SIA GAL NAG 0.003033 0.47045 1.52091
3 4CU1 H4B 0.02241 0.42612 2.28137
4 1Z82 G3H 0.02654 0.41468 2.6616
5 1Z82 G3P 0.03229 0.41008 2.6616
6 4BGB ADP 0.02111 0.41184 3.42205
7 2H21 SAM 0.000009943 0.52429 3.80228
8 4PPF FLC 0.03158 0.41612 3.80228
9 3LRE ADP 0.03262 0.41289 4.18251
10 3N71 SFG 0.000003927 0.40619 7.98479
11 1U1J C2F 0.01074 0.4385 11.0266
12 4NOS H4B 0.04007 0.41112 11.7871
13 4NOS H2B 0.0482 0.40592 11.7871
14 4DS0 A2G GAL NAG FUC 0.02425 0.42861 12.8834
15 1JZN BGC GAL 0.01429 0.41857 15.5556
16 5T0K SAM 0.00002878 0.41022 17.4905
17 5JIY SAM 0.00001923 0.40822 17.4905
18 5M5G SAH 0.00001886 0.53362 20.9125
19 5M5G VAL MET LEU PRO GLY ARG GLY VAL PRO 0.0000004466 0.50259 20.9125
20 3KMT SAH 0.000008955 0.5678 21.8487
Pocket No.: 2; Query (leader) PDB : 5AYF; Ligand: C7H; Similar sites found: 18
This union binding pocket(no: 2) in the query (biounit: 5ayf.bio1) has 41 residues
No: Leader PDB Ligand P-value (APoc) PS_Score (APoc) Sequence Similarity
1 2BVE PH5 0.00813 0.41372 None
2 5LFV SIA GAL NAG 0.003345 0.47045 1.52091
3 4CU1 H4B 0.02447 0.42612 2.28137
4 1Z82 G3H 0.0276 0.41598 2.6616
5 1Z82 G3P 0.03337 0.4115 2.6616
6 5AHS FAD 0.01375 0.40299 3.04183
7 2H21 SAM 0.00001052 0.52667 3.80228
8 4PPF FLC 0.03432 0.41612 3.80228
9 3LRE ADP 0.03553 0.41289 4.18251
10 1U1J C2F 0.01182 0.4385 11.0266
11 4NOS H4B 0.04368 0.41112 11.7871
12 4DS0 A2G GAL NAG FUC 0.02632 0.42861 12.8834
13 1JZN BGC GAL 0.01552 0.41857 15.5556
14 5T0K SAM 0.00002349 0.404 17.4905
15 5JIY SAM 0.00001656 0.40119 17.4905
16 5M5G SAH 0.00001241 0.54524 20.9125
17 5M5G VAL MET LEU PRO GLY ARG GLY VAL PRO 0.000000594 0.5076 20.9125
18 3KMT SAH 0.00000796 0.57373 21.8487
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