Receptor
PDB id Resolution Class Description Source Keywords
3FUD 2.2 Å EC: 3.3.2.6 LEUKOTRIENE A4 HYDROLASE IN COMPLEX WITH N-METHYL-1-(2-THIOP YLPHENYL)METHANAMINE HOMO SAPIENS LEUKOTRIENE A4 HYDROLASE LTA4H FRAGMENT CRYSTALLOGRAPHY FOF LIFE FOL ALTERNATIVE SPLICING CYTOPLASM HYDROLASE LEUKOTRIENE BIOSYNTHESIS METAL-BINDING METALLOPROTEASE MULTIFUNCTIONAL ENZYME POLYMORPHISM PROTEASE ZINC
Ref.: DISCOVERY OF LEUKOTRIENE A4 HYDROLASE INHIBITORS US METABOLOMICS BIASED FRAGMENT CRYSTALLOGRAPHY. J.MED.CHEM. V. 52 4694 2009
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
692 A:710;
 Valid;
 none;
 ic50 > 2000 uM
203.303 C12 H13 N S CNCc1...
ACT A:801;
 Invalid;
 none;
 submit data
59.044 C2 H3 O2 CC(=O...
IMD A:802;
A:803;
 Invalid;
Invalid;
 none;
none;
 submit data
69.085 C3 H5 N2 c1c[n...
YB A:702;
 Invalid;
 none;
 submit data
173.04 Yb [Yb+3...
ZN A:701;
 Part of Protein;
 none;
 submit data
65.409 Zn [Zn+2...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
2VJ8 1.8 Å EC: 3.3.2.6 COMPLEX OF HUMAN LEUKOTRIENE A4 HYDROLASE WITH A HYDROXAMIC INHIBITOR HOMO SAPIENS HYDROXAMIC ACID LEUKOTRIENE HYDROLASE ZINC PROTEASE HYDRMETALLOPROTEASE
Ref.: CRYSTAL STRUCTURES OF LEUKOTRIENE A4 HYDROLASE IN C WITH CAPTOPRIL AND TWO COMPETITIVE TIGHT-BINDING IN FASEB J. V. 16 1648 2002
Members (48)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3FTW - 11X C12 H12 N2 c1ccc(cc1)....
2 3FUK ic50 = 966 uM 58Z C16 H20 N2 O3 c1cc2c(cc[....
3 3FU6 ic50 = 106 uM 80G C11 H11 N S c1cc(sc1)c....
4 6END ic50 = 0.133 uM BGK C13 H8 N2 O2 S c1cc2c(nc1....
5 3FUI ic50 = 0.157 uM 812 C18 H22 N2 O c1ccc(cc1)....
6 3FU5 ic50 = 75.2 uM 492 C9 H9 N S2 c1cc(sc1)c....
7 2R59 Ki = 6.5 nM PH0 C27 H31 N2 O5 P c1ccc(cc1)....
8 5N3W ic50 = 0.5 uM 8KW C15 H16 O3 COc1cc(cc(....
9 3CHP ic50 = 5400 nM 4BO C17 H18 N2 O4 c1ccc(cc1)....
10 4L2L Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
11 1HS6 - BES C16 H24 N2 O4 CC(C)C[C@@....
12 6ENB - PRO GLY PRO n/a n/a
13 3B7T - ARG ALA ARG n/a n/a
14 3B7R Ki = 20 nM BIR C21 H27 N2 O5 P C[C@@H](C(....
15 3FUN ic50 = 0.189 uM 798 C22 H21 N O2 S c1cc(ccc1c....
16 3FTX - BES C16 H24 N2 O4 CC(C)C[C@@....
17 5NI4 - DJ3 C20 H30 O3 CCCCC/C=CC....
18 3CHR ic50 = 61 nM 4BS C17 H20 N2 O2 c1ccc(cc1)....
19 3B7S - ARG SER ARG n/a n/a
20 2VJ8 Ki = 0.002 uM HA2 C22 H28 N2 O5 c1ccc(cc1)....
21 3FUH - BES C16 H24 N2 O4 CC(C)C[C@@....
22 5AEN ic50 = 0.06 uM DP8 C16 H19 N O2 CN(C)CCOc1....
23 4MS6 - 28T C13 H20 N2 O4 C1C[C@H](N....
24 3FUE ic50 = 1510 uM 11S C8 H6 Cl N c1cc2c(cc[....
25 3FH8 ic50 = 180 nM 27P C19 H23 N O c1ccc(cc1)....
26 5BPP ic50 = 15.86 uM A4Z C12 H17 N O3 CCCCOc1ccc....
27 3FTZ - 848 C12 H12 N2 O c1ccc(c(c1....
28 5NI6 - DJ3 C20 H30 O3 CCCCC/C=CC....
29 3FTV ic50 = 1667 uM 11X C12 H12 N2 c1ccc(cc1)....
30 3CHQ ic50 = 20 nM 4BQ C18 H20 N2 O4 c1ccc(cc1)....
31 3FUL ic50 = 199 uM 52D C18 H20 N2 O2 c1cc(ccc1C....
32 3FTS ic50 = 212 uM STL C14 H12 O3 c1cc(ccc1C....
33 3FHE - 28P C20 H25 N O3 C[N@@](CCC....
34 6ENC ic50 = 0.019 uM BGW C20 H20 N2 O3 S c1ccc2c(c1....
35 3FUM ic50 = 170 uM 80A C18 H22 N2 O2 c1cc(ccc1[....
36 3B7U - KEL C14 H18 N2 O5 C[C@@H](C(....
37 3FTY ic50 = 619 uM 3IP C12 H12 N2 O c1ccc(cc1)....
38 3FTU ic50 = 247 uM RE2 C14 H14 O3 c1cc(ccc1C....
39 3FH7 Kd = 25 nM 25P C21 H23 Cl N O4 c1cc(ccc1O....
40 3FUJ ic50 = 234 uM 00G C14 H14 N2 O c1ccn(c1)C....
41 3FU0 ic50 = 5308 uM 22F C12 H8 F N O c1cc(ccc1C....
42 3FH5 ic50 = 87 nM 24P C18 H21 N O c1ccc(cc1)....
43 3CHO ic50 = 280 nM 4BG C15 H16 N2 O2 c1ccc(cc1)....
44 3FUD ic50 > 2000 uM 692 C12 H13 N S CNCc1ccccc....
45 3FU3 ic50 = 1443 uM 92G C9 H8 N2 O S c1cc(ccc1c....
46 4MKT Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
47 5NI2 - DJ3 C20 H30 O3 CCCCC/C=CC....
48 1GW6 - BES C16 H24 N2 O4 CC(C)C[C@@....
70% Homology Family (49)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 2 families.
1 3FTW - 11X C12 H12 N2 c1ccc(cc1)....
2 3FUK ic50 = 966 uM 58Z C16 H20 N2 O3 c1cc2c(cc[....
3 3FU6 ic50 = 106 uM 80G C11 H11 N S c1cc(sc1)c....
4 6END ic50 = 0.133 uM BGK C13 H8 N2 O2 S c1cc2c(nc1....
5 3FUI ic50 = 0.157 uM 812 C18 H22 N2 O c1ccc(cc1)....
6 3FU5 ic50 = 75.2 uM 492 C9 H9 N S2 c1cc(sc1)c....
7 2R59 Ki = 6.5 nM PH0 C27 H31 N2 O5 P c1ccc(cc1)....
8 5N3W ic50 = 0.5 uM 8KW C15 H16 O3 COc1cc(cc(....
9 3CHP ic50 = 5400 nM 4BO C17 H18 N2 O4 c1ccc(cc1)....
10 4L2L Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
11 1HS6 - BES C16 H24 N2 O4 CC(C)C[C@@....
12 6ENB - PRO GLY PRO n/a n/a
13 3B7T - ARG ALA ARG n/a n/a
14 3B7R Ki = 20 nM BIR C21 H27 N2 O5 P C[C@@H](C(....
15 3FUN ic50 = 0.189 uM 798 C22 H21 N O2 S c1cc(ccc1c....
16 3FTX - BES C16 H24 N2 O4 CC(C)C[C@@....
17 5NI4 - DJ3 C20 H30 O3 CCCCC/C=CC....
18 3CHR ic50 = 61 nM 4BS C17 H20 N2 O2 c1ccc(cc1)....
19 3B7S - ARG SER ARG n/a n/a
20 2VJ8 Ki = 0.002 uM HA2 C22 H28 N2 O5 c1ccc(cc1)....
21 3FUH - BES C16 H24 N2 O4 CC(C)C[C@@....
22 5AEN ic50 = 0.06 uM DP8 C16 H19 N O2 CN(C)CCOc1....
23 4MS6 - 28T C13 H20 N2 O4 C1C[C@H](N....
24 3FUE ic50 = 1510 uM 11S C8 H6 Cl N c1cc2c(cc[....
25 3FH8 ic50 = 180 nM 27P C19 H23 N O c1ccc(cc1)....
26 5BPP ic50 = 15.86 uM A4Z C12 H17 N O3 CCCCOc1ccc....
27 3FTZ - 848 C12 H12 N2 O c1ccc(c(c1....
28 5NI6 - DJ3 C20 H30 O3 CCCCC/C=CC....
29 3FTV ic50 = 1667 uM 11X C12 H12 N2 c1ccc(cc1)....
30 3CHQ ic50 = 20 nM 4BQ C18 H20 N2 O4 c1ccc(cc1)....
31 3FUL ic50 = 199 uM 52D C18 H20 N2 O2 c1cc(ccc1C....
32 3FTS ic50 = 212 uM STL C14 H12 O3 c1cc(ccc1C....
33 3FHE - 28P C20 H25 N O3 C[N@@](CCC....
34 6ENC ic50 = 0.019 uM BGW C20 H20 N2 O3 S c1ccc2c(c1....
35 3FUM ic50 = 170 uM 80A C18 H22 N2 O2 c1cc(ccc1[....
36 3B7U - KEL C14 H18 N2 O5 C[C@@H](C(....
37 3FTY ic50 = 619 uM 3IP C12 H12 N2 O c1ccc(cc1)....
38 3FTU ic50 = 247 uM RE2 C14 H14 O3 c1cc(ccc1C....
39 3FH7 Kd = 25 nM 25P C21 H23 Cl N O4 c1cc(ccc1O....
40 3FUJ ic50 = 234 uM 00G C14 H14 N2 O c1ccn(c1)C....
41 3FU0 ic50 = 5308 uM 22F C12 H8 F N O c1cc(ccc1C....
42 3FH5 ic50 = 87 nM 24P C18 H21 N O c1ccc(cc1)....
43 3CHO ic50 = 280 nM 4BG C15 H16 N2 O2 c1ccc(cc1)....
44 3FUD ic50 > 2000 uM 692 C12 H13 N S CNCc1ccccc....
45 3FU3 ic50 = 1443 uM 92G C9 H8 N2 O S c1cc(ccc1c....
46 4MKT Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
47 5NI2 - DJ3 C20 H30 O3 CCCCC/C=CC....
48 1GW6 - BES C16 H24 N2 O4 CC(C)C[C@@....
49 4GAA - BES C16 H24 N2 O4 CC(C)C[C@@....
50% Homology Family (50)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 1 families.
1 3FTW - 11X C12 H12 N2 c1ccc(cc1)....
2 3FUK ic50 = 966 uM 58Z C16 H20 N2 O3 c1cc2c(cc[....
3 3FU6 ic50 = 106 uM 80G C11 H11 N S c1cc(sc1)c....
4 6END ic50 = 0.133 uM BGK C13 H8 N2 O2 S c1cc2c(nc1....
5 3FUI ic50 = 0.157 uM 812 C18 H22 N2 O c1ccc(cc1)....
6 3FU5 ic50 = 75.2 uM 492 C9 H9 N S2 c1cc(sc1)c....
7 2R59 Ki = 6.5 nM PH0 C27 H31 N2 O5 P c1ccc(cc1)....
8 5N3W ic50 = 0.5 uM 8KW C15 H16 O3 COc1cc(cc(....
9 3CHP ic50 = 5400 nM 4BO C17 H18 N2 O4 c1ccc(cc1)....
10 4L2L Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
11 1HS6 - BES C16 H24 N2 O4 CC(C)C[C@@....
12 6ENB - PRO GLY PRO n/a n/a
13 3B7T - ARG ALA ARG n/a n/a
14 3B7R Ki = 20 nM BIR C21 H27 N2 O5 P C[C@@H](C(....
15 3FUN ic50 = 0.189 uM 798 C22 H21 N O2 S c1cc(ccc1c....
16 3FTX - BES C16 H24 N2 O4 CC(C)C[C@@....
17 5NI4 - DJ3 C20 H30 O3 CCCCC/C=CC....
18 3CHR ic50 = 61 nM 4BS C17 H20 N2 O2 c1ccc(cc1)....
19 3B7S - ARG SER ARG n/a n/a
20 2VJ8 Ki = 0.002 uM HA2 C22 H28 N2 O5 c1ccc(cc1)....
21 3FUH - BES C16 H24 N2 O4 CC(C)C[C@@....
22 5AEN ic50 = 0.06 uM DP8 C16 H19 N O2 CN(C)CCOc1....
23 4MS6 - 28T C13 H20 N2 O4 C1C[C@H](N....
24 3FUE ic50 = 1510 uM 11S C8 H6 Cl N c1cc2c(cc[....
25 3FH8 ic50 = 180 nM 27P C19 H23 N O c1ccc(cc1)....
26 5BPP ic50 = 15.86 uM A4Z C12 H17 N O3 CCCCOc1ccc....
27 3FTZ - 848 C12 H12 N2 O c1ccc(c(c1....
28 5NI6 - DJ3 C20 H30 O3 CCCCC/C=CC....
29 3FTV ic50 = 1667 uM 11X C12 H12 N2 c1ccc(cc1)....
30 3CHQ ic50 = 20 nM 4BQ C18 H20 N2 O4 c1ccc(cc1)....
31 3FUL ic50 = 199 uM 52D C18 H20 N2 O2 c1cc(ccc1C....
32 3FTS ic50 = 212 uM STL C14 H12 O3 c1cc(ccc1C....
33 3FHE - 28P C20 H25 N O3 C[N@@](CCC....
34 6ENC ic50 = 0.019 uM BGW C20 H20 N2 O3 S c1ccc2c(c1....
35 3FUM ic50 = 170 uM 80A C18 H22 N2 O2 c1cc(ccc1[....
36 3B7U - KEL C14 H18 N2 O5 C[C@@H](C(....
37 3FTY ic50 = 619 uM 3IP C12 H12 N2 O c1ccc(cc1)....
38 3FTU ic50 = 247 uM RE2 C14 H14 O3 c1cc(ccc1C....
39 3FH7 Kd = 25 nM 25P C21 H23 Cl N O4 c1cc(ccc1O....
40 3FUJ ic50 = 234 uM 00G C14 H14 N2 O c1ccn(c1)C....
41 3FU0 ic50 = 5308 uM 22F C12 H8 F N O c1cc(ccc1C....
42 3FH5 ic50 = 87 nM 24P C18 H21 N O c1ccc(cc1)....
43 3CHO ic50 = 280 nM 4BG C15 H16 N2 O2 c1ccc(cc1)....
44 3FUD ic50 > 2000 uM 692 C12 H13 N S CNCc1ccccc....
45 3FU3 ic50 = 1443 uM 92G C9 H8 N2 O S c1cc(ccc1c....
46 4MKT Ki = 2.3 uM 1V6 C16 H14 N2 S c1ccc(cc1)....
47 5NI2 - DJ3 C20 H30 O3 CCCCC/C=CC....
48 1GW6 - BES C16 H24 N2 O4 CC(C)C[C@@....
49 4GAA - BES C16 H24 N2 O4 CC(C)C[C@@....
50 2XQ0 - BES C16 H24 N2 O4 CC(C)C[C@@....
Polypharmacology
Similar Ligands (2D)
Ligand no: 1; Ligand: 692; Similar ligands found: 1
No: Ligand ECFP6 Tc MDL keys Tc
1 692 1 1
Similar Ligands (3D)
Ligand no: 1; Ligand: 692; Similar ligands found: 360
No: Ligand Similarity coefficient
1 7I2 0.9499
2 1X8 0.9497
3 2D3 0.9491
4 JR2 0.9481
5 BPS 0.9461
6 XQK 0.9449
7 ZZ8 0.9424
8 BQ5 0.9409
9 PRZ 0.9402
10 60Q 0.9392
11 F69 0.9343
12 6XI 0.9320
13 BCK 0.9297
14 F12 0.9285
15 GV9 0.9285
16 X0W 0.9272
17 9AP 0.9263
18 ESI 0.9254
19 B4O 0.9253
20 1Z8 0.9236
21 VXX 0.9221
22 DNC 0.9217
23 8WZ 0.9212
24 LDR 0.9212
25 P9I 0.9203
26 M1Z 0.9197
27 878 0.9194
28 KTW 0.9184
29 2JK 0.9183
30 AY4 0.9180
31 ZME 0.9179
32 4ME 0.9179
33 49O 0.9169
34 7WR 0.9162
35 25O 0.9159
36 IPT 0.9144
37 1FF 0.9141
38 NIG 0.9138
39 C9E 0.9138
40 VNL 0.9136
41 6J9 0.9130
42 DK1 0.9124
43 0W1 0.9119
44 I6G 0.9108
45 89J 0.9107
46 A9O 0.9104
47 OKM 0.9097
48 VM1 0.9097
49 1X7 0.9094
50 55D 0.9092
51 OBP 0.9092
52 MOK 0.9091
53 61O 0.9087
54 JP2 0.9087
55 CH9 0.9080
56 BPU 0.9077
57 K3Y 0.9076
58 HQJ 0.9075
59 BZE 0.9073
60 8G6 0.9069
61 N2Z 0.9064
62 SYR 0.9063
63 463 0.9060
64 TQU 0.9058
65 L5V 0.9056
66 AIN 0.9054
67 II4 0.9049
68 LEL 0.9047
69 QPR 0.9045
70 TWO 0.9045
71 52C 0.9042
72 HLD 0.9039
73 W8G 0.9038
74 7FF 0.9037
75 F2W 0.9037
76 49N 0.9029
77 M1H 0.9028
78 8NX 0.9024
79 HNQ 0.9024
80 4MU 0.9024
81 GVG 0.9021
82 8XQ 0.9016
83 EVO 0.9013
84 X8D 0.9013
85 ONR 0.9010
86 97T 0.9009
87 DNF 0.9007
88 QSH 0.9003
89 Z5P 0.9003
90 MPK 0.8999
91 WOE 0.8999
92 512 0.8996
93 KYA 0.8996
94 N7I 0.8995
95 R20 0.8995
96 B2T 0.8994
97 BPY 0.8988
98 SQ4 0.8986
99 XM5 0.8985
100 JRB 0.8985
101 QZ8 0.8980
102 9FE 0.8976
103 GHM 0.8974
104 0GZ 0.8973
105 AM1 0.8973
106 MUR 0.8968
107 FGZ 0.8966
108 NBG 0.8964
109 EWG 0.8955
110 GDE 0.8947
111 SQ7 0.8946
112 YTX 0.8939
113 7ME 0.8938
114 6PB 0.8936
115 RME 0.8934
116 2LY 0.8934
117 M5H 0.8929
118 AJY 0.8927
119 1A7 0.8925
120 WUB 0.8923
121 5VJ 0.8920
122 N3W 0.8919
123 1WC 0.8918
124 SQP 0.8916
125 TNF 0.8916
126 CKU 0.8916
127 LFQ 0.8907
128 54X 0.8907
129 982 0.8906
130 5F8 0.8905
131 0FK 0.8901
132 AQK 0.8900
133 ACE PHE 0.8900
134 J9Q 0.8898
135 QM1 0.8898
136 SR4 0.8896
137 M0Q 0.8892
138 5TZ 0.8892
139 C2Y 0.8888
140 O2Y 0.8885
141 7ZL 0.8884
142 PJW 0.8883
143 V55 0.8882
144 TT4 0.8881
145 39O 0.8881
146 1XA 0.8881
147 UFV 0.8879
148 YO5 0.8877
149 FOT 0.8875
150 GNV 0.8873
151 BEA 0.8873
152 AX3 0.8873
153 C4L 0.8870
154 ALA LEU 0.8870
155 QBK 0.8868
156 0LO 0.8867
157 XFE 0.8865
158 E35 0.8865
159 7VS 0.8864
160 LF5 0.8862
161 8GK 0.8862
162 MXD 0.8861
163 BK9 0.8860
164 F31 0.8858
165 8HC 0.8857
166 67X 0.8857
167 92P 0.8856
168 L22 0.8855
169 EXD 0.8853
170 0F9 0.8850
171 GRX 0.8848
172 CKA 0.8848
173 091 0.8848
174 DNA 0.8846
175 T2D 0.8846
176 BN1 0.8845
177 FF2 0.8845
178 3Y7 0.8844
179 JTA 0.8844
180 90J 0.8844
181 M5N 0.8843
182 P7Y 0.8841
183 JKZ 0.8841
184 NCT 0.8839
185 PDC 0.8838
186 KW8 0.8837
187 EOL 0.8833
188 EV0 0.8831
189 U7E 0.8831
190 A9P 0.8831
191 FE DB1 0.8830
192 PH2 0.8827
193 6BL 0.8824
194 H5B 0.8823
195 0GY 0.8822
196 SRO 0.8820
197 D07 0.8820
198 AW5 0.8817
199 2HC 0.8815
200 M0W 0.8815
201 DHK 0.8812
202 LL1 0.8810
203 1QP 0.8809
204 0N7 0.8807
205 ANC 0.8806
206 V6F 0.8806
207 2D0 0.8805
208 8WT 0.8804
209 JG8 0.8803
210 4NO 0.8797
211 KFN 0.8796
212 4A5 0.8795
213 344 0.8795
214 NQH 0.8795
215 5V7 0.8793
216 8HH 0.8792
217 226 0.8790
218 FLV 0.8790
219 X11 0.8790
220 8TX 0.8787
221 G1P 0.8786
222 HQD 0.8783
223 2ZQ 0.8780
224 GF4 0.8777
225 2AK 0.8777
226 34D 0.8776
227 APZ 0.8773
228 V1T 0.8772
229 96R 0.8770
230 KUF 0.8768
231 B21 0.8767
232 774 0.8767
233 7ZE 0.8765
234 3C5 0.8765
235 IHB 0.8765
236 D1X 0.8761
237 5VL 0.8758
238 JAA 0.8757
239 C2U 0.8757
240 IJZ 0.8756
241 8W9 0.8755
242 K2P 0.8754
243 4XV 0.8753
244 QSB 0.8752
245 ZYR 0.8751
246 61M 0.8750
247 SYA 0.8749
248 OMD 0.8749
249 KDO 0.8745
250 GNJ 0.8743
251 N8Q 0.8741
252 RD4 0.8740
253 HKK 0.8738
254 URC 0.8736
255 FDR 0.8735
256 DQU 0.8733
257 CIY 0.8733
258 NCD 0.8733
259 6DP 0.8731
260 AEH 0.8726
261 FBG 0.8726
262 CHB 0.8726
263 2AL 0.8725
264 H7Y 0.8724
265 K3Q 0.8723
266 JTH 0.8722
267 MBG 0.8722
268 0P6 0.8721
269 9TW 0.8721
270 ORO 0.8720
271 S7B 0.8717
272 GNM 0.8716
273 4KL 0.8713
274 QMS 0.8712
275 6ME 0.8711
276 FER 0.8710
277 QX4 0.8709
278 OAI 0.8708
279 6NI 0.8708
280 JND 0.8707
281 7B3 0.8707
282 5PX 0.8705
283 TR4 0.8703
284 MYI 0.8699
285 2F6 0.8697
286 GT0 0.8695
287 B62 0.8694
288 2J9 0.8692
289 MHK 0.8691
290 GJK 0.8690
291 P4L 0.8689
292 HHS 0.8686
293 6QF 0.8685
294 OSB 0.8684
295 MZM 0.8681
296 DBJ 0.8680
297 5OF 0.8680
298 SHA 0.8678
299 DOR 0.8676
300 NLA 0.8671
301 6VD 0.8668
302 HPT 0.8667
303 OXC 0.8666
304 5WY 0.8663
305 8VE 0.8662
306 M1E 0.8660
307 CKX 0.8654
308 P9P 0.8651
309 GTR 0.8651
310 OTD 0.8649
311 4XS 0.8646
312 R8Y 0.8643
313 KDM 0.8641
314 3IT 0.8641
315 64C 0.8640
316 H05 0.8640
317 MIG 0.8640
318 XZ8 0.8636
319 XH2 0.8635
320 DHB 0.8634
321 ALA GLU 0.8631
322 42C 0.8631
323 OTW 0.8629
324 44V 0.8628
325 DIU 0.8628
326 8WO 0.8625
327 HA5 0.8623
328 PLP 0.8621
329 CLZ 0.8619
330 SBK 0.8617
331 SLY 0.8615
332 BNL 0.8614
333 ALA DGL 0.8613
334 BDP 0.8611
335 UKV 0.8602
336 MPV 0.8599
337 Q24 0.8598
338 S3P 0.8596
339 AVO 0.8592
340 M6Z 0.8589
341 MJ2 0.8585
342 GLY PHE 0.8581
343 HJ8 0.8578
344 6OT 0.8577
345 STT 0.8576
346 NIR 0.8571
347 9X5 0.8568
348 UAN 0.8567
349 2KU 0.8566
350 KTA 0.8564
351 TZM 0.8562
352 J9W 0.8556
353 AKD 0.8550
354 AME 0.8549
355 GLY MET 0.8540
356 93K 0.8539
357 IBM 0.8536
358 NPL 0.8534
359 NFQ 0.8528
360 SKM 0.8517
Similar Binding Sites (Proteins are less than 50% similar to leader)
Pocket No.: 1; Query (leader) PDB : 2VJ8; Ligand: HA2; Similar sites found with APoc: 1
This union binding pocket(no: 1) in the query (biounit: 2vj8.bio1) has 40 residues
No: Leader PDB Ligand Sequence Similarity
1 6Q4R HJ5 24.5499
APoc FAQ
Feedback