Receptor
PDB id Resolution Class Description Source Keywords
3G2C 2.3 Å EC: 3.1.11.2 MTH0212 IN COMPLEX WITH A SHORT SSDNA (CGTA) METHANOTHERMOBACTER THERMAUTOTROPHICUSORGANISM_TAXID: 187420 PROTEIN-DNA COMPLEX SINGLE-STRANDED DNA FLIPPED NUCLEOTIDEMG2+ HYDROLASE-DNA COMPLEX
Ref.: CRYSTAL STRUCTURE ANALYSIS OF DNA URIDINE ENDONUCLE MTH212 BOUND TO DNA J.MOL.BIOL. V. 399 604 2010
Ligand
Ligand Chain:Residue Validity Ligand Warnings Binding Data NGL Viewer Molecular Weight (Da) Formula SMILES
DC DG DT DA I:1;
Valid;
none;
submit data
1248.77 n/a [P+](...
GOL A:266;
A:267;
A:268;
A:269;
A:270;
A:274;
I:5;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
Invalid;
none;
none;
none;
none;
none;
none;
none;
submit data
92.094 C3 H8 O3 C(C(C...
MG A:271;
B:266;
Part of Protein;
Part of Protein;
none;
none;
submit data
24.305 Mg [Mg+2...
PO4 A:272;
A:273;
B:267;
Invalid;
Invalid;
Invalid;
none;
none;
none;
submit data
94.971 O4 P [O-]P...
View in 3D viewer
90% Homology Family
Leader
PDB id Resolution Class Description Source Keywords
3G2C 2.3 Å EC: 3.1.11.2 MTH0212 IN COMPLEX WITH A SHORT SSDNA (CGTA) METHANOTHERMOBACTER THERMAUTOTROPHICUSORGANISM_TAXID: 187420 PROTEIN-DNA COMPLEX SINGLE-STRANDED DNA FLIPPED NUCLEOTIDEMG2+ HYDROLASE-DNA COMPLEX
Ref.: CRYSTAL STRUCTURE ANALYSIS OF DNA URIDINE ENDONUCLE MTH212 BOUND TO DNA J.MOL.BIOL. V. 399 604 2010
Members (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 4 families.
1 3G2C - DC DG DT DA n/a n/a
70% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3G2C - DC DG DT DA n/a n/a
50% Homology Family (1)
No: PDB id Binding Data Representative ligand Formula Smiles
The Class containing this family consists of a total of 3 families.
1 3G2C - DC DG DT DA n/a n/a
Polypharmacology
Similar Ligands
Ligand no: 1; Ligand: DC DG DT DA; Similar ligands found: 42
No: Ligand ECFP6 Tc MDL keys Tc
1 DC DG DT DA 1 1
2 DT DA DC DG 0.978873 1
3 DA DC DG DA 0.824324 0.952941
4 DG DA DC DG 0.817568 0.952941
5 DC DG DA DC 0.783784 0.952381
6 DA DT DA DA 0.709459 0.917647
7 DC DG 0.646259 0.941176
8 DG DT DC 0.625806 0.965116
9 DG DC 0.608974 0.929412
10 DC DC DT DG 0.576389 0.833333
11 DU DU DU DU BRU DA DU 0.569697 0.853933
12 DU DU DU DU BRU DG DU 0.569697 0.910112
13 CGP 0.544872 0.918605
14 DT MA7 DT 0.538922 0.918605
15 DG DG 0.52381 0.917647
16 CPA 0.519231 0.883721
17 3PD UM3 0.509434 0.917647
18 PAX 0.491124 0.929412
19 DA DU DG DA 0.466258 0.906977
20 DT DC 0.4625 0.825581
21 DT DT PST 0.451613 0.784091
22 ADS THS THS THS 0.449704 0.865169
23 DT ME6 DT 0.445122 0.837209
24 U A G G 0.443787 0.870588
25 G C 0.440476 0.883721
26 G G G RPC 0.440476 0.904762
27 A G U 0.43956 0.895349
28 A G C C 0.439306 0.894118
29 4TA 0.43787 0.929412
30 U G A 0.429348 0.895349
31 DT DT DT DT DT 0.423077 0.813953
32 G A A A 0.421053 0.860465
33 DGP 0.417808 0.870588
34 DG 0.417808 0.870588
35 G G G C 0.417143 0.895349
36 APC G U 0.413793 0.870588
37 U A C C 0.413793 0.870588
38 Z5A 0.407821 0.897727
39 DT DT DT 0.406667 0.77907
40 G C C C 0.405556 0.883721
41 A U C C 0.402174 0.860465
42 DGI 0.401316 0.860465
Similar Binding Sites (Proteins are less than 50% similar to leader)
Feedback